Novel insights into the synergistic interaction of Bortezomib and TRAIL: tBid provides the link
- The proteasome inhibitor Bortezomib has been identified as a potent enhancer of TRAIL-induced apoptosis in several human cancers. However, the identification of the underlying molecular mechanisms of this synergistic cell death induction has been ongoing over the last years. A recent study identifies a new mechanism of action for the synergism of TRAIL and Bortezomib.
Author: | Simone FuldaORCiDGND |
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URN: | urn:nbn:de:hebis:30-102383 |
URL: | http://www.impactjournals.com/oncotarget/index.php?journal=oncotarget&page=article&op=view&path[]=277&path[]=421 |
DOI: | https://doi.org/10.18632/oncotarget.277 |
ISSN: | 1949-2553 |
Parent Title (English): | Oncotarget |
Publisher: | Impact Journals LLC |
Place of publication: | [S.l.] |
Document Type: | Article |
Language: | English |
Date of Publication (online): | 2011/05/16 |
Date of first Publication: | 2011/05/16 |
Publishing Institution: | Universitätsbibliothek Johann Christian Senckenberg |
Release Date: | 2011/08/08 |
Tag: | TRAIL; apoptosis; cancer; chemotherapy; proteasome inhibitor |
Volume: | 2 |
Issue: | 5 |
Page Number: | 4 |
First Page: | 418 |
Last Page: | 421 |
Note: | Copyright: © Fulda. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
HeBIS-PPN: | 272535168 |
Institutes: | Medizin / Medizin |
Dewey Decimal Classification: | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
Sammlungen: | Universitätspublikationen |
Licence (German): | Creative Commons - Namensnennung 3.0 |