Motor control stabilisation exercise for non-specific low back pain patients : a prospective meta-analysis with multilevel meta-regressions on intervention effects
- Low-to-moderate quality meta-analytic evidence shows that motor control stabilisation exercise (MCE) is an effective treatment of non-specific low back pain. A possible approach to overcome the weaknesses of traditional meta-analyses would be that of a prospective meta-analyses. The aim of the present analysis was to generate high-quality evidence to support the view that motor control stabilisation exercises (MCE) lead to a reduction in pain intensity and disability in non-specific low back pain patients when compared to a control group. In this prospective meta-analysis and sensitivity multilevel meta-regression within the MiSpEx-Network, 18 randomized controlled study arms were included. Participants with non-specific low back pain were allocated to an intervention (individualized MCE, 12 weeks) or a control group (no additive exercise intervention). From each study site/arm, outcomes at baseline, 3 weeks, 12 weeks, and 6 months were pooled. The outcomes were current pain (NRS or VAS, 11 points scale), characteristic pain intensity, and subjective disability. A random effects meta-analysis model for continuous outcomes to display standardized mean differences between intervention and control was performed, followed by sensitivity multilevel meta-regressions. Overall, 2391 patients were randomized; 1976 (3 weeks, short-term), 1740 (12 weeks, intermediate), and 1560 (6 months, sustainability) participants were included in the meta-analyses. In the short-term, intermediate and sustainability, moderate-to-high quality evidence indicated that MCE has a larger effect on current pain (SMD = −0.15, −0.15, −0.19), pain intensity (SMD = −0.19, −0.26, −0.26) and disability (SMD = −0.15, −0.27, −0.25) compared with no exercise intervention. Low-quality evidence suggested that those patients with comparably intermediate current pain and older patients may profit the most from MCE. Motor control stabilisation exercise is an effective treatment for non-specific low back pain. Sub-clinical intermediate pain and middle-aged patients may profit the most from this intervention.
Author: | Daniel NiedererORCiDGND, Tilman EngelORCiDGND, Lutz VogtGND, Adamantios ArampatzisORCiDGND, Winfried BanzerGND, Heidrun BeckORCiDGND, María Moreno Catalá, Michael Brenner-Fliesser, Claas Güthoff, Thore Haag, Alexander Hönning, Ann-Christin Pfeifer, Petra Platen, Marcus SchiltenwolfORCiDGND, Christian Schneider, Katharina Trompeter, Pia-Maria WippertORCiDGND, Frank Mayer |
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URN: | urn:nbn:de:hebis:30:3-562210 |
DOI: | https://doi.org/10.3390/jcm9093058 |
ISSN: | 2077-0383 |
Parent Title (English): | Journal of Clinical Medicine |
Publisher: | MDPI |
Place of publication: | Basel |
Document Type: | Article |
Language: | English |
Date of Publication (online): | 2020/09/22 |
Date of first Publication: | 2020/09/22 |
Publishing Institution: | Universitätsbibliothek Johann Christian Senckenberg |
Release Date: | 2020/10/08 |
Tag: | LBP; chronic low back pain; exercise; lumbago; lumbalgia; meta-analysis; nonspecific; sensorimotor; stabilization; unspecific low back pain motor control exercise |
Volume: | 9 |
Issue: | 9, art. 3058 |
Page Number: | 19 |
First Page: | 1 |
Last Page: | 19 |
Note: | This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited |
HeBIS-PPN: | 473120070 |
Institutes: | Psychologie und Sportwissenschaften |
Dewey Decimal Classification: | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
Sammlungen: | Universitätspublikationen |
Open-Access-Publikationsfonds: | Psychologie und Sportwissenschaften |
Licence (German): | Creative Commons - Namensnennung 4.0 |