Lange nicht-codierende RNAs in der Angiogenese
- More than 97 percent of the transcribed RNA in mammalian cells is not coding for proteins. Among these are micro RNAs (miRs), transfer RNAs (tRNA) as well as ribosomal RNAs (rRNA) but also long non-coding RNAs (lncRNAs). This RNA class is only defined by its sequence length of more than 200 nucleotides and its lack of protein coding potential. The human genome encodes for more than 18.000 lncRNAs which contribute to gene expression control. Here, we discuss the function of these lncRNAs and how they modulate the angiogenic process of vessel growth.
Author: | Ralf BrandesORCiDGND, Matthias LeisegangORCiDGND |
---|---|
URN: | urn:nbn:de:hebis:30:3-637982 |
DOI: | https://doi.org/10.1007/s12268-021-1546-z |
ISSN: | 1868-6249 |
Parent Title (German): | Biospektrum |
Publisher: | Spektrum |
Place of publication: | Heidelberg |
Document Type: | Article |
Language: | German |
Date of Publication (online): | 2021/03/23 |
Date of first Publication: | 2021/03/23 |
Publishing Institution: | Universitätsbibliothek Johann Christian Senckenberg |
Release Date: | 2022/08/22 |
Volume: | 27.2021 |
Issue: | 2 |
Page Number: | 3 |
First Page: | 146 |
Last Page: | 148 |
Note: | Open Access funding enabled and organized by Projekt DEAL. |
HeBIS-PPN: | 502534427 |
Institutes: | Medizin |
Dewey Decimal Classification: | 5 Naturwissenschaften und Mathematik / 57 Biowissenschaften; Biologie / 570 Biowissenschaften; Biologie |
6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit | |
Sammlungen: | Universitätspublikationen |
Licence (German): | Creative Commons - Namensnennung 4.0 |