Martin Obermeier, Thomas Berg, Nadine Sichtig, Patrick Braun, Martin P. Däumer, Hauke Walter, Christian Noah, Eva Wolf, Harm Müller, Martin Stürmer, Alexander Thielen, Rolf Kaiser
- Poster presentation: Background Maraviroc is a new drug used to treat HIV infection from the new class of drugs called CCR5 entry inhibitors. As the active principle of these drugs is to block the CCR5-receptor on the surface of the target cells, it has to be known if the virus in the patient is using only CCR5 as co-receptor or if there are populations that can also use CXCR4. Therefore, an assay to determine the tropism has to be performed before starting a therapy. Besides phenotypic assays like the TROFILE® assay by Monogram, used in the approval studies, there exist several genotyping systems like geno2pheno-coreceptor, Wetcat (providing five different genotypic tropism schemes) and WebPSSM. ...
MetadatenAuthor: | Martin Obermeier, Thomas BergORCiDGND, Nadine Sichtig, Patrick Braun, Martin P. Däumer, Hauke Walter, Christian Noah, Eva Wolf, Harm Müller, Martin StürmerORCiDGND, Alexander Thielen, Rolf Kaiser |
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URN: | urn:nbn:de:hebis:30-70719 |
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DOI: | https://doi.org/10.1186/1758-2652-11-S1-P201 |
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Parent Title (German): | Journal of the International AIDS Society ; from Ninth International Congress on Drug Therapy in HIV Infection Glasgow, UK. 9–13 November 2008 |
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Document Type: | Article |
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Language: | English |
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Date of Publication (online): | 2009/09/20 |
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Year of first Publication: | 2008 |
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Publishing Institution: | Universitätsbibliothek Johann Christian Senckenberg |
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Release Date: | 2009/09/20 |
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Volume: | 11 |
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Issue: | (Suppl 1):P201 |
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Note: | © 2008 Obermeier et al; licensee BioMed Central Ltd. |
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Source: | Journal of the International AIDS Society 2008, 11(Suppl 1):P201 ; doi:10.1186/1758-2652-11-S1-P201 ; from Ninth International Congress on Drug Therapy in HIV Infection Glasgow, UK. 9–13 November 2008 |
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HeBIS-PPN: | 218882068 |
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Institutes: | Medizin / Medizin |
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Dewey Decimal Classification: | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
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Licence (German): | Deutsches Urheberrecht |
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