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- Bipolar disorder (1)
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In psychiatry, there has been a growing focus on identifying at-risk populations. For schizophrenia, these efforts have led to the development of early recognition and intervention measures. Despite a similar disease burden, the populations at risk of bipolar disorder have not been sufficiently characterized. Within the BipoLife consortium, we used magnetic resonance imaging (MRI) data from a multicenter study to assess structural gray matter alterations in N = 263 help-seeking individuals from seven study sites. We defined the risk using the EPIbipolar assessment tool as no-risk, low-risk, and high-risk and used a region-of-interest approach (ROI) based on the results of two large-scale multicenter studies of bipolar disorder by the ENIGMA working group. We detected significant differences in the thickness of the left pars opercularis (Cohen’s d = 0.47, p = 0.024) between groups. The cortex was significantly thinner in high-risk individuals compared to those in the no-risk group (p = 0.011). We detected no differences in the hippocampal volume. Exploratory analyses revealed no significant differences in other cortical or subcortical regions. The thinner cortex in help-seeking individuals at risk of bipolar disorder is in line with previous findings in patients with the established disorder and corresponds to the region of the highest effect size in the ENIGMA study of cortical alterations. Structural alterations in prefrontal cortex might be a trait marker of bipolar risk. This is the largest structural MRI study of help-seeking individuals at increased risk of bipolar disorder.
In critical or nearly critical heavy-ion collisions, induced as well as spontaneous energyless e-e+ pair creation result in the decay of the neutral vacuum. Induced transitions from the negative-energy continuum into a vacant molecular 1s level can occur even in the absence of diving and produce a substantial enhancement and broadening of the previously considered spontaneous positron spectrum. Total cross sections of 5 b have been calculated for U-U collisions.
We present calculations for the impact-parameter dependence of K-shell ionization rates in p¯-Cu and in p¯-Ag collisions at various projectile energies. We show that the effect of the attractive Coulomb potential on the Rutherford trajectory and the antibinding effect caused by the negative charge of the antiproton result in a considerable increase of the ionization probability. Total ionization cross sections for proton and antiproton projectiles are compared with each other and with experimental ionization cross sections for protons.
The magnetic dipole scattering of neutrinos by the electrostatic potentials of single atoms as well as crystals is investigated. It is shown that scattering by a rigid cubic lattice can amplify the neutrino-atom cross section by a factor of N1/3, N being the number of scatterers. However, comparing the results with typical weak-interaction cross sections, the effect seems to be not observable in experiment.
A new spontaneous-symmetry-breaking mechanism is formulated for SU(3), which is used to describe the formation of bags around quarks. The Higgs field is replaced by the scalar product of two colored fermion fields. This model gives mass only to one gluon (equivalent to Aμ8) when spontaneously broken. The consequences of this scheme are discussed, and it is argued that it can explain several puzzling high-energy heavy-ion experiments.
We investigate the influence of additional nonlinear terms in the Dirac Lagrangian on strongly bound electron states in heavy and superheavy atoms. Upper bounds for the coupling constants are deduced by comparison with precision spectroscopy data in QED. We demonstrate that nonlinear interactions may cause significant modifications of electron binding energies in superheavy quasiatomic systems which would not be visible in ordinary atomic-physics measurements.
We consider the contribution of nuclear polarization to the Lamb shift of K- and L-shell electrons in heavy atoms and quasiatoms. Our formal approach is based on the concept of effective photon propagators with nuclear-polarization insertions treating effects of nuclear polarization on the same footing as usual QED radiative corrections. We explicitly derive the modification of the photon propagator for various collective nuclear excitations and calculate the corresponding effective self-energy shift perturbatively. The energy shift of the 1s1/2 state in 92238U due to virtual excitation of nuclear rotational states is shown to be a considerable correction for atomic high-precision experiments. In contrast to this, nuclear-polarization effects are of minor importance for Lamb-shift studies in 82208Pb.
Phase transitions in nuclear matter A method for the description of spin-isospin phase transitions in nuclear matter is developed. It allows a complete description of the pion condensation phase transition in the framework of the Landau-Migdal Fermi liquid theory. The equation of the order parameter is derived and the condensation energy is calculated. We study the influence of pion condensation on the nuclear equation of state and the temperature dependence of pion condensation. NUCLEAR STRUCTURE Description of pion-condensed ground state by Green's function technique.
Phenomenological consequences of a hypothetical light neutral particle in heavy ion collisions
(1986)
We discuss the possibility that the line structure observed in the spectrum of the positrons produced in heavy ion collisions is due to the decay of a new neutral elementary particle. We argue that this can be ruled out unless one is willing to accept fine tuning of parameters, or to assume the dominance of nonlinear effects.