Refine
Year of publication
Document Type
- Article (107)
- Preprint (37)
- Report (1)
- Working Paper (1)
Has Fulltext
- yes (146)
Is part of the Bibliography
- no (146)
Keywords
- LHC (7)
- Mammakarzinom (6)
- breast cancer (6)
- Behandlung (4)
- Studien (4)
- trials (4)
- ALICE (3)
- ALICE experiment (3)
- Hadron-Hadron Scattering (3)
- pp collisions (3)
- Beauty production (2)
- CDK4/6 (2)
- Diagnostik (2)
- Früherkennung (2)
- Galaktografie (2)
- Galaktomosynthese (2)
- HNSCC (2)
- Inflammation (2)
- Lokalrezidiv (2)
- MRI (2)
- MRT (2)
- Mamma (2)
- Metastasen (2)
- Nachsorge (2)
- PD1/PDL1 (2)
- Prognosefaktoren (2)
- Prädiktivfaktoren (2)
- Prävention (2)
- Richtlinie (2)
- Risiko (2)
- Single electrons (2)
- Tomosynthese (2)
- Ultraschall (2)
- breast (2)
- diagnosis (2)
- follow‑up (2)
- galactography (2)
- galactomosynthesis (2)
- guideline (2)
- local recurrence (2)
- predictive factors (2)
- prevention (2)
- prognostic factors (2)
- prostate cancer (2)
- risk (2)
- screening (2)
- tomosynthesis (2)
- treatment (2)
- treatment/therapy (2)
- ultrasound (2)
- 900 GeV (1)
- Active middle ear implants (1)
- Advanced breast cancer (1)
- Aeroplysinin-1 (1)
- Anandamide (1)
- Angiogenesis (1)
- Animal models (1)
- Anti-seizure medication (1)
- Antihormone therapy (1)
- Artificial Intelligence (1)
- Auditory system (1)
- Bezeichnungen (1)
- Biocatalysis (1)
- Biodiversity (1)
- Biodiversity Data (1)
- Biomonitoring (1)
- Bone conduction devices (1)
- Botanical Collections (1)
- Brain tumors (1)
- CCL2 (1)
- COVID (1)
- COVID-19 (1)
- CRISPR/Cas (1)
- Cancer (1)
- Capecitabine (1)
- Charm physics (1)
- Children and adolescents (1)
- Chocó rainforest (1)
- Compact astrophysical objects (1)
- Comparison with QCD (1)
- Computerspielstörung (1)
- Consensus statement (1)
- Conservation (1)
- Conservation biogeography (1)
- Digitization (1)
- D’Amico classification (1)
- EGFR (1)
- Ecosystem services (1)
- Ecuador (1)
- Endothelial cells (1)
- Energy modelling (1)
- Enzyme mechanisms (1)
- Epilepsy (1)
- Epithelioma Cells (1)
- Everolimus (1)
- FDG-PET/CT (1)
- FDM (1)
- Femtoscopy (1)
- Forschungsdatenmanagement (1)
- Galaxies and clusters (1)
- Gaussian Process (1)
- Gene regulation (1)
- Genetic wildlife monitoring (1)
- Genome editing (1)
- Geschichtsunterricht (1)
- Gleason score (1)
- Glücksspielstörung (1)
- HBT (1)
- HDAC4 (1)
- HER2 c-erbB2 (1)
- HER2/neu (1)
- HPV-positive OPSCC (1)
- Hadron production (1)
- Hair sampling (1)
- Head neck cancer (1)
- Health policy (1)
- Heavy Ions (1)
- Heavy flavor production (1)
- Heavy flavour production (1)
- Heavy ions (1)
- Heavy-flavour production (1)
- Heavy-ion collisions (1)
- Herbaria (1)
- Heregulin (1)
- High-energy astrophysics (1)
- Human well-being (1)
- ICD-11 (1)
- Immunology (1)
- Immunotherapy (1)
- Inclusive spectra (1)
- Induction therapy (1)
- Intensity interferometry (1)
- Jets (1)
- Judenvernichtung (1)
- KCNQ4 (1)
- Landesinitiative (1)
- Landesinitiative für Forschungsdatenmanagement (1)
- Lee-type (1)
- Leukemia (1)
- Lure sticks (1)
- Lymphoma Cells (1)
- MM-121 (1)
- Mediation (1)
- Metastatic (1)
- Metastatic breast cancer (1)
- Mid-rapidity (1)
- Mixed hearing loss (1)
- Multi-stakeholder approach (1)
- Multi-strange baryons (1)
- Multiple Kernel (1)
- NCoR1 (1)
- NFDI (1)
- Nationale Forschungsdateninfrastruktur (1)
- Nationalsozialismus (1)
- Natural product (1)
- Nature (1)
- Noninvasive genetic sampling (1)
- Nuclear modification factor (1)
- Nucleolar protein 14 (1)
- Oncology (1)
- Open data (1)
- Open source (1)
- PELICAN (1)
- PROM (1)
- PYTHIA (1)
- Patient reported outcomes (1)
- Pb–Pb (1)
- Pegylated liposomal doxorubicin (1)
- Protein synthesis (1)
- Proton–proton (1)
- Public health (1)
- QOL (1)
- RBC (1)
- RDM (1)
- Red blood cell transfusion (1)
- Rehabilitation (1)
- Relativistic heavy ion physics (1)
- Research Data Management (1)
- Research Infrastructure (1)
- Rhabdomyoma (1)
- SARS-CoV-2 (1)
- Sarcomas (1)
- Seizure (1)
- Semantics (1)
- Seribantumab (1)
- Single muons (1)
- Social participation (1)
- Support Vector Regression (1)
- Support Vector Regression Model (1)
- Surgery (1)
- T-DM1 (1)
- TKI (1)
- Taxonomy (1)
- Technical data (1)
- Transcriptional regulatory elements (1)
- Transverse momentum (1)
- Unterrichtsmethode (1)
- Verhaltenssucht (1)
- Vioprolide A (1)
- Virtual Screening (1)
- X-ray crystallography (1)
- aboveground biomass (1)
- accident (1)
- acute coronary syndrome (1)
- acute myeloid leukaemia (1)
- advanced breast cancer (1)
- anaemia (1)
- antihormone therapy (1)
- apex (1)
- behavioral addiction (1)
- biodiversity (1)
- buccal mucosal graft urethroplasty (1)
- cancer (1)
- cetuximab (1)
- chemotherapy (1)
- chloroplast membrane proteins (1)
- chronosequence (1)
- cochlea (1)
- combined modality therapy (1)
- copeptin (1)
- double immune checkpoint inhibition (1)
- elderly patients (1)
- envelope membrane proteome approach comparison (1)
- functional outcome (1)
- gambling disorder (1)
- gaming disorder (1)
- head and neck cancer (1)
- head and neck neoplasms (1)
- immune-checkpoint inhibition (1)
- immunotherapy (1)
- induction chemotherapy (1)
- induction therapy (1)
- injury (1)
- inverse stage migration (1)
- lapatinib (1)
- lockdown (1)
- mTOR (1)
- mTOR inhibitor (1)
- mass spectrometry (1)
- membrane proteome (1)
- membranous urethra (1)
- metastases (1)
- metastasis (1)
- metastatic (1)
- mid-term urinary continence (1)
- mortality (1)
- myocardial infarction (1)
- neutralizing antibodies (1)
- organ preservation (1)
- pancreatic cancer (1)
- patient-reported outcome measure (1)
- pediatric intensive care (1)
- pertuzumab (1)
- plant proteomics (1)
- radical prostatecomy (1)
- radical prostatectomy (1)
- re-irradiation (1)
- reassembly (1)
- registry (1)
- resilience (1)
- resistance (1)
- spectra (1)
- spike protein (1)
- surgery (1)
- targeted therapy (1)
- terminology (1)
- transfusion (1)
- trastuzumab (1)
- trauma (1)
- trees (1)
- troponin (1)
- urethral stricture (1)
- urethroplasty (1)
- variants of concern (1)
- √sN N = 2.76 TeV (1)
Institute
- Physik (80)
- Frankfurt Institute for Advanced Studies (FIAS) (70)
- Informatik (68)
- Medizin (47)
- Senckenbergische Naturforschende Gesellschaft (5)
- Biochemie und Chemie (4)
- Biowissenschaften (4)
- Institut für Ökologie, Evolution und Diversität (3)
- Biodiversität und Klima Forschungszentrum (BiK-F) (2)
- Biochemie, Chemie und Pharmazie (1)
Ziele: Das Ziel dieser offiziellen Leitlinie, die von der Deutschen Gesellschaft für Gynäkologie und Geburtshilfe (DGGG) und der Deutschen Krebsgesellschaft (DKG) publiziert und koordiniert wurde, ist es, die Früherkennung, Diagnostik, Therapie und Nachsorge des Mammakarzinoms zu optimieren.
Methoden: Der Aktualisierungsprozess der S3-Leitlinie aus 2012 basierte zum einen auf der Adaptation identifizierter Quellleitlinien und zum anderen auf Evidenzübersichten, die nach Entwicklung von PICO-(Patients/Interventions/Control/Outcome-)Fragen, systematischer Recherche in Literaturdatenbanken sowie Selektion und Bewertung der gefundenen Literatur angefertigt wurden. In den interdisziplinären Arbeitsgruppen wurden auf dieser Grundlage Vorschläge für Empfehlungen und Statements erarbeitet, die im Rahmen von strukturierten Konsensusverfahren modifiziert und graduiert wurden.
Empfehlungen: Der Teil 1 dieser Kurzversion der Leitlinie zeigt Empfehlungen zur Früherkennung, Diagnostik und Nachsorge des Mammakarzinoms: Der Stellenwert des Mammografie-Screenings wird in der aktualisierten Leitlinienversion bestätigt und bildet damit die Grundlage der Früherkennung. Neben den konventionellen Methoden der Karzinomdiagnostik wird die Computertomografie (CT) zum Staging bei höherem Rückfallrisiko empfohlen. Die Nachsorgekonzepte beinhalten Untersuchungsintervalle für die körperliche Untersuchung, Ultraschall und Mammografie, während weiterführende Gerätediagnostik und Tumormarkerbestimmungen bei der metastasierten Erkrankung Anwendung finden.
Purpose: The aim of this official guideline coordinated and published by the German Society for Gynecology and Obstetrics (DGGG) and the German Cancer Society (DKG) was to optimize the screening, diagnosis, therapy and follow-up care of breast cancer.
Methods: The process of updating the S3 guideline dating from 2012 was based on the adaptation of identified source guidelines which were combined with reviews of evidence compiled using PICO (Patients/Interventions/Control/Outcome) questions and the results of a systematic search of literature databases and the selection and evaluation of the identified literature. The interdisciplinary working groups took the identified materials as their starting point to develop recommendations and statements which were modified and graded in a structured consensus procedure.
Recommendations: Part 1 of this short version of the guideline presents recommendations for the screening, diagnosis and follow-up care of breast cancer. The importance of mammography for screening is confirmed in this updated version of the guideline and forms the basis for all screening. In addition to the conventional methods used to diagnose breast cancer, computed tomography (CT) is recommended for staging in women with a higher risk of recurrence. The follow-up concept includes suggested intervals between physical, ultrasound and mammography examinations, additional high-tech diagnostic procedures, and the determination of tumor markers for the evaluation of metastatic disease.
Long-range angular correlations on the near and away side in p–Pb collisions at √sNN=5.02 TeV
(2013)
Angular correlations between charged trigger and associated particles are measured by the ALICE detector in p–Pb collisions at a nucleon–nucleon centre-of-mass energy of 5.02 TeV for transverse momentum ranges within 0.5<pT,assoc<pT,trig<4 GeV/c. The correlations are measured over two units of pseudorapidity and full azimuthal angle in different intervals of event multiplicity, and expressed as associated yield per trigger particle. Two long-range ridge-like structures, one on the near side and one on the away side, are observed when the per-trigger yield obtained in low-multiplicity events is subtracted from the one in high-multiplicity events. The excess on the near-side is qualitatively similar to that recently reported by the CMS Collaboration, while the excess on the away-side is reported for the first time. The two-ridge structure projected onto azimuthal angle is quantified with the second and third Fourier coefficients as well as by near-side and away-side yields and widths. The yields on the near side and on the away side are equal within the uncertainties for all studied event multiplicity and pT bins, and the widths show no significant evolution with event multiplicity or pT. These findings suggest that the near-side ridge is accompanied by an essentially identical away-side ridge.
A measurement of the transverse momentum spectra of jets in Pb-Pb collisions at sNN−−−√=2.76 TeV is reported. Jets are reconstructed from charged particles using the anti-kT jet algorithm with jet resolution parameters R of 0.2 and 0.3 in pseudo-rapidity |η|<0.5. The transverse momentum pT of charged particles is measured down to 0.15 GeV/c which gives access to the low pT fragments of the jet. Jets found in heavy-ion collisions are corrected event-by-event for average background density and on an inclusive basis (via unfolding) for residual background fluctuations and detector effects. A strong suppression of jet production in central events with respect to peripheral events is observed. The suppression is found to be similar to the suppression of charged hadrons, which suggests that substantial energy is radiated at angles larger than the jet resolution parameter R=0.3 considered in the analysis. The fragmentation bias introduced by selecting jets with a high pT leading particle, which rejects jets with a soft fragmentation pattern, has a similar effect on the jet yield for central and peripheral events. The ratio of jet spectra with R=0.2 and R=0.3 is found to be similar in Pb-Pb and simulated PYTHIA pp events, indicating no strong broadening of the radial jet structure in the reconstructed jets with R<0.3.
The transverse momentum (pT) spectrum and nuclear modification factor (RAA) of reconstructed jets in 0–10% and 10–30% central Pb–Pb collisions at √sNN = 2.76 TeV were measured. Jets were reconstructed using the anti-kT jet algorithm with a resolution parameter of R = 0.2 from charged and neutral particles, utilizing the ALICE tracking detectors and Electromagnetic Calorimeter (EMCal). The jet pT spectra are reported in the pseudorapidity interval of |ηjet| < 0.5 for 40 < pT, jet < 120 GeV/c in 0–10% and for 30 < pT, jet < 100 GeV/c in 10–30% collisions. Reconstructed jets were required to contain a leading charged particle with pT > 5 GeV/c to suppress jets constructed from the combinatorial background in Pb–Pb collisions. The leading charged particle requirement applied to jet spectra both in pp and Pb–Pb collisions had a negligible effect on the RAA. The nuclear modification factor RAA was found to be 0.28 ± 0.04 in 0–10% and 0.35 ± 0.04 in 10–30% collisions, independent of pT, jet within the uncertainties of the measurement. The observed suppression is in fair agreement with expectations from two model calculations with different approaches to jet quenching.
We have performed the first measurement of the coherent ψ(2S) photo production cross section in ultraperipheral Pb–Pb collisions at the LHC. This charmonium excited state is reconstructed via the ψ(2S) → l +l − and ψ(2S) → J/ψπ+π− decays, where the J/ψ decays into two leptons. The analysis is based on an event sample corresponding to an integrated luminosity of about 22 μb−1. The cross section for coherent ψ(2S) production in the rapidity interval −0.9 < y < 0.9 is dσcoh ψ(2S)/dy = 0.83±0.19 stat+syst mb. The ψ(2S) to J/ψ coherent cross section ratio is 0.34+0.08 −0.07(stat + syst). The obtained results are compared to predictions from theoretical models.
A measurement of dijet correlations in p–Pb collisions at √sNN = 5.02 TeV with the ALICE detector is presented. Jets are reconstructed from charged particles measured in the central tracking detectors and neutral energy deposited in the electromagnetic calorimeter. The transverse momentum of the full jet (clustered from charged and neutral constituents) and charged jet (clustered from charged particles only) is corrected event-by-event for the contribution of the underlying event, while corrections for underlying event fluctuations and finite detector resolution are applied on an inclusive basis. A projection of the dijet transverse momentum, kTy = pch+ne T,jet sin(ϕdijet) with ϕdijet the azimuthal angle between a full and charged jet and pch+ne T,jet the transverse momentum of the full jet, is used to study nuclear matter effects in p–Pb collisions. This observable is sensitive to the acoplanarity of dijet production and its potential modification in p–Pb collisions with respect to pp collisions. Measurements of the dijet kTy as a function of the transverse momentum of the full and recoil charged jet, and the event multiplicity are presented. No significant modification of kTy due to nuclear matter effects in p–Pb collisions with respect to the event multiplicity or a PYTHIA8 reference is observed.
The measurement of the mass differences for systems bound by the strong force has reached a very high precision with protons and anti-protons1,2. The extension of such measurement from (anti-)baryons to (anti-)nuclei allows one to probe any difference in the interactions between nucleons and anti-nucleons encoded in the (anti-)nuclei masses. This force is a remnant of the underlying strong interaction among quarks and gluons and can be described by effective theories3, but cannot yet be directly derived from quantum chromodynamics. Here we report a measurement of the difference between the ratios of the mass and charge of deuterons (d) and anti-deuterons (), and 3He and nuclei carried out with the ALICE (A Large Ion Collider Experiment)4 detector in Pb–Pb collisions at a centre-of-mass energy per nucleon pair of 2.76 TeV. Our direct measurement of the mass-over-charge differences confirms CPT invariance to an unprecedented precision in the sector of light nuclei5,6. This fundamental symmetry of nature, which exchanges particles with anti-particles, implies that all physics laws are the same under the simultaneous reversal of charge(s) (charge conjugation C), reflection of spatial coordinates (parity transformation P) and time inversion (T).
The ALICE Collaboration at the LHC reports measurement of the inclusive production cross section of electrons from semi-leptonic decays of beauty hadrons with rapidity |y| < 0.8 and transverse momentum 1 < pT < 10 GeV/c, in pp collisions at √s = 2.76 TeV. Electrons not originating from semi-electronic decay of beauty hadrons are suppressed using the impact parameter of the corresponding tracks. The production cross section of beauty decay electrons is compared to the result obtained with an alternative method which uses the distribution of the azimuthal angle between heavy-flavour decay electrons and charged hadrons. Perturbative QCD predictions agree with the measured cross section within the experimental and theoretical uncertainties. The integrated visible cross section, σb→e = 3.47 ± 0.40(stat) +1.12 −1.33(sys) ± 0.07(norm) μb, was extrapolated to full phase space using Fixed Order plus Next-to-Leading Log (FONLL) calculations to obtain the total bb production ¯ cross section, σbb¯ = 130 ± 15.1(stat) +42.1 −49.8(sys) +3.4 −3.1(extr) ± 2.5(norm) ± 4.4(BR) μb.
Transverse momentum spectra of π±, K± and p(p¯) up to pT = 20 GeV/c at mid-rapidity in pp, peripheral (60–80%) and central (0–5%) Pb–Pb collisions at √sNN = 2.76 TeV have been measured using the ALICE detector at the Large Hadron Collider. The proton-to-pion and the kaon-to-pion ratios both show a distinct peak at pT ≈ 3 GeV/c in central Pb–Pb collisions. Below the peak, pT < 3 GeV/c, both ratios are in good agreement with hydrodynamical calculations, suggesting that the peak itself is dominantly the result of radial flow rather than anomalous hadronization processes. For pT > 10 GeV/c particle ratios in pp and Pb–Pb collisions are in agreement and the nuclear modification factors for π±, K± and p(p¯) indicate that, within the systematic and statistical uncertainties, the suppression is the same. This suggests that the chemical composition of leading particles from jets in the medium is similar to that of vacuum jets.