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Introduction: Acute kidney injury (AKI) can evolve quickly and clinical measures of function often fail to detect AKI at a time when interventions are likely to provide benefit. Identifying early markers of kidney damage has been difficult due to the complex nature of human AKI, in which multiple etiologies exist. The objective of this study was to identify and validate novel biomarkers of AKI.
Methods: We performed two multicenter observational studies in critically ill patients at risk for AKI - discovery and validation. The top two markers from discovery were validated in a second study (Sapphire) and compared to a number of previously described biomarkers. In the discovery phase, we enrolled 522 adults in three distinct cohorts including patients with sepsis, shock, major surgery, and trauma and examined over 300 markers. In the Sapphire validation study, we enrolled 744 adult subjects with critical illness and without evidence of AKI at enrollment; the final analysis cohort was a heterogeneous sample of 728 critically ill patients. The primary endpoint was moderate to severe AKI (KDIGO stage 2 to 3) within 12 hours of sample collection.
Results: Moderate to severe AKI occurred in 14% of Sapphire subjects. The two top biomarkers from discovery were validated. Urine insulin-like growth factor-binding protein 7 (IGFBP7) and tissue inhibitor of metalloproteinases-2 (TIMP-2), both inducers of G1 cell cycle arrest, a key mechanism implicated in AKI, together demonstrated an AUC of 0.80 (0.76 and 0.79 alone). Urine [TIMP-2].[IGFBP7] was significantly superior to all previously described markers of AKI (P <0.002), none of which achieved an AUC >0.72. Furthermore, [TIMP-2].[IGFBP7] significantly improved risk stratification when added to a nine-variable clinical model when analyzed using Cox proportional hazards model, generalized estimating equation, integrated discrimination improvement or net reclassification improvement. Finally, in sensitivity analyses [TIMP-2].[IGFBP7] remained significant and superior to all other markers regardless of changes in reference creatinine method.
Conclusions: Two novel markers for AKI have been identified and validated in independent multicenter cohorts. Both markers are superior to existing markers, provide additional information over clinical variables and add mechanistic insight into AKI. Trial registration: ClinicalTrials.gov number NCT01209169.
A(syn)-U/T and G(syn)-C+ Hoogsteen (HG) base pairs (bps) are energetically more disfavored relative to Watson–Crick (WC) bps in A-RNA as compared to B-DNA by >1 kcal/mol for reasons that are not fully understood. Here, we used NMR spectroscopy, optical melting experiments, molecular dynamics simulations and modified nucleotides to identify factors that contribute to this destabilization of HG bps in A-RNA. Removing the 2′-hydroxyl at single purine nucleotides in A-RNA duplexes did not stabilize HG bps relative to WC. In contrast, loosening the A-form geometry using a bulge in A-RNA reduced the energy cost of forming HG bps at the flanking sites to B-DNA levels. A structural and thermodynamic analysis of purine-purine HG mismatches reveals that compared to B-DNA, the A-form geometry disfavors syn purines by 1.5–4 kcal/mol due to sugar-backbone rearrangements needed to sterically accommodate the syn base. Based on MD simulations, an additional penalty of 3–4 kcal/mol applies for purine-pyrimidine HG bps due to the higher energetic cost associated with moving the bases to form hydrogen bonds in A-RNA versus B-DNA. These results provide insights into a fundamental difference between A-RNA and B-DNA duplexes with important implications for how they respond to damage and post-transcriptional modifications.
Azimuthally-differential femtoscopic measurements, being sensitive to spatio-temporal characteristics of the source as well as to the collective velocity fields at freeze out, provide very important information on the nature and dynamics of the system evolution. While the HBT radii oscillations relative to the second harmonic event plane measured recently reflect mostly the spatial geometry of the source, model studies have shown that the HBT radii oscillations relative to the third harmonic event plane are predominantly defined by the velocity fields. In this Letter, we present the first results on azimuthally-differential pion femtoscopy relative to the third harmonic event plane as a function of the pion pair transverse momentum kT for different collision centralities in Pb–Pb collisions at √sNN = 2.76 TeV. We find that the Rside and Rout radii, which characterize the pion source size in the directions perpendicular and parallel to the pion transverse momentum, oscillate in phase relative to the third harmonic event plane, similar to the results from 3+1D hydrodynamical calculations. The observed radii oscillations unambiguously signal a collective expansion and anisotropy in the velocity fields. A comparison of the measured radii scillations with the Blast-Wave model calculations indicate that the initial state triangularity is washedout at freeze out.
The first measurements of anisotropic flow coefficients vn for mid-rapidity charged particles in Xe–Xe collisions at √sNN = 5.44 TeV are presented. Comparing these measurements to those from Pb–Pb collisions at √sNN = 5.02 TeV, v2 is found to be suppressed for mid-central collisions at the same centrality, and enhanced for central collisions. The values of v3 are generally larger in Xe–Xe than in Pb–Pb at a given centrality. These observations are consistent with expectations from hydrodynamic predictions. When both v2 and v3 are divided by their corresponding eccentricities for a variety of initial state models, they generally scale with transverse density when comparing Xe–Xe and Pb–Pb, with some deviations observed in central Xe–Xe and Pb–Pb collisions. These results assist in placing strong constraints on both the initial state geometry and medium response for relativistic heavy-ion collisions.
The production of the charm-strange baryon Ξc0 is measured for the first time at the LHC via its semileptonic decay into eΞ−+νe in pp collisions at s=7 TeV with the ALICE detector. The transverse momentum (pT) differential cross section multiplied by the branching ratio is presented in the interval 1<pT<8 GeV/c at mid-rapidity, |y|<0.5. The transverse momentum dependence of the Ξc0 baryon production relative to the D0 meson production is compared to predictions of event generators with various tunes of the hadronisation mechanism, which are found to underestimate the measured cross-section ratio.
We present a measurement of azimuthal correlations between inclusive J/ψ and charged hadrons in p–Pb collisions recorded with the ALICE detector at the CERN LHC. The J/ψ are reconstructed at forward (p-going, 2.03<y<3.53) and backward (Pb-going, −4.46<y<−2.96) rapidity via their μ+μ− decay channel, while the charged hadrons are reconstructed at mid-rapidity (|η|<1.8). The correlations are expressed in terms of associated charged-hadron yields per J/ψ trigger. A rapidity gap of at least 1.5 units is required between the trigger J/ψ and the associated charged hadrons. Possible correlations due to collective effects are assessed by subtracting the associated per-trigger yields in the low-multiplicity collisions from those in the high-multiplicity collisions. After the subtraction, we observe a strong indication of remaining symmetric structures at Δφ≈0 and Δφ≈π, similar to those previously found in two-particle correlations at middle and forward rapidity. The corresponding second-order Fourier coefficient (v2) in the transverse momentum interval between 3 and 6 GeV/c is found to be positive with a significance of about 5σ. The obtained results are similar to the J/ψ v2 coefficients measured in Pb–Pb collisions at sNN=5.02 TeV, suggesting a common mechanism at the origin of the J/ψ v2.
This paper presents the measurements of π±, K±, p and p¯¯¯ transverse momentum (pT) spectra as a function of charged-particle multiplicity density in proton–proton (pp) collisions at s√ = 13 TeV with the ALICE detector at the LHC. Such study allows us to isolate the center-of-mass energy dependence of light-flavour particle production. The measurements reported here cover a pT range from 0.1 to 20 GeV/c and are done in the rapidity interval |y|<0.5. The pT-differential particle ratios exhibit an evolution with multiplicity, similar to that observed in pp collisions at s√ = 7 TeV, which is qualitatively described by some of the hydrodynamical and pQCD-inspired models discussed in this paper. Furthermore, the pT-integrated hadron-to-pion yield ratios measured in pp collisions at two different center-of-mass energies are consistent when compared at similar multiplicities. This also extends to strange and multi-strange hadrons, suggesting that, at LHC energies, particle hadrochemistry scales with particle multiplicity the same way under different collision energies and colliding systems.
The measurement of the azimuthal-correlation function of prompt D mesons with charged particles in pp collisions at s√=5.02 TeV and p–Pb collisions at sNN−−−√=5.02 TeV with the ALICE detector at the LHC is reported. The D0, D+, and D∗+ mesons, together with their charge conjugates, were reconstructed at midrapidity in the transverse momentum interval 3<pT<24 GeV/c and correlated with charged particles having pT>0.3 GeV/c and pseudorapidity |η|<0.8. The properties of the correlation peaks appearing in the near- and away-side regions (for Δφ≈0 and Δφ≈π, respectively) were extracted via a fit to the azimuthal correlation functions. The shape of the correlation functions and the near- and away-side peak features are found to be consistent in pp and p–Pb collisions, showing no modifications due to nuclear effects within uncertainties. The results are compared with predictions from Monte Carlo simulations performed with the PYTHIA, POWHEG+PYTHIA, HERWIG, and EPOS 3 event generators.
The pseudorapidity density of charged particles, dNch/dη, in p–Pb collisions has been measured at a centre-of-mass energy per nucleon–nucleon pair of sNN−−−√ = 8.16 TeV at mid-pseudorapidity for non-single-diffractive events. The results cover 3.6 units of pseudorapidity, |η|<1.8. The dNch/dη value is 19.1±0.7 at |η|<0.5. This quantity divided by ⟨Npart⟩ / 2 is 4.73±0.20, where ⟨Npart⟩is the average number of participating nucleons, is 9.5% higher than the corresponding value for p–Pb collisions at sNN−−−√ = 5.02 TeV. Measurements are compared with models based on different mechanisms for particle production. All models agree within uncertainties with data in the Pb-going side, while HIJING overestimates, showing a symmetric behaviour, and EPOS underestimates the p-going side of the dNch/dη distribution. Saturation-based models reproduce the distributions well for η>−1.3. The dNch/dη is also measured for different centrality estimators, based both on the charged-particle multiplicity and on the energy deposited in the Zero-Degree Calorimeters. A study of the implications of the large multiplicity fluctuations due to the small number of participants for systems like p–Pb in the centrality calculation for multiplicity-based estimators is discussed, demonstrating the advantages of determining the centrality with energy deposited near beam rapidity.
Measurement of the inclusive isolated photon production cross section in pp collisions at √s = 7 TeV
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The production cross section of inclusive isolated photons has been measured by the ALICE experiment at the CERN LHC in pp collisions at a centre-of-momentum energy of s√= 7 TeV. The measurement is performed with the electromagnetic calorimeter EMCal and the central tracking detectors, covering a range of |η|<0.27 in pseudorapidity and a transverse momentum range of 10<pγT<60 GeV/c. The result extends the pT coverage of previously published results of the ATLAS and CMS experiments at the same collision energy to smaller pT. The measurement is compared to next-to-leading order perturbative QCD calculations and to the results from the ATLAS and CMS experiments. All measurements and theory predictions are in agreement with each other.
We present a study of the inclusive charged-particle transverse momentum (pT) spectra as a function of charged-particle multiplicity density at mid-pseudorapidity, dNch/dη, in pp collisions at s√=5.02 and 13 TeV covering the kinematic range |η|<0.8 and 0.15<pT<20 GeV/c. The results are presented for events with at least one charged particle in |η|<1 (INEL>0). The pT spectra are reported for two multiplicity estimators covering different pseudorapidity regions. The pT spectra normalized to that for INEL>0 show little energy dependence. Moreover, the high-pT yields of charged particles increase faster than the charged-particle multiplicity density. The average pT as a function of multiplicity and transverse spherocity is reported for pp collisions at s√=13 TeV. For low- (high-) spherocity events, corresponding to jet-like (isotropic) events, the average pT is higher (smaller) than that measured in INEL>0 pp collisions. Within uncertainties, the functional form of ⟨pT⟩(Nch) is not affected by the spherocity selection. While EPOS LHC gives a good description of many features of data, PYTHIA overestimates the average pT in jet-like events.
The production of charm jets in proton-proton collisions at a center-of-mass energy of s√=7 TeV was measured with the ALICE detector at the CERN Large Hadron Collider. The measurement is based on a data sample corresponding to a total integrated luminosity of 6.23 nb−1, collected using a minimum-bias trigger. Charm jets are identified by the presence of a D0 meson among their constituents. The D0 mesons are reconstructed from their hadronic decay D0 →K−π+. The D0-meson tagged jets are reconstructed using tracks of charged particles (track-based jets) with the anti-kT algorithm in the jet transverse momentum range 5<pchT,jet< 30 GeV/c and pseudorapidity |ηjet| < 0.5. The fraction of charged jets containing a D0-meson increases with pchT,jet from 0.042 ± 0.004 (stat) ± 0.006 (syst) to 0.080 ± 0.009 (stat) ± 0.008 (syst). The distribution of D0-meson tagged jets as a function of the jet momentum fraction carried by the D0 meson in the direction of the jet axis (zch∥) is reported for two ranges of jet transverse momenta, 5<pchT,jet< 15 GeV/c and 15<pchT,jet< 30 GeV/c in the intervals 0.2<zch∥∥<1.0 and 0.4<zch∥∥<1.0, respectively. The data are compared with results from Monte Carlo event generators (PYTHIA 6, PYTHIA 8 and Herwig 7) and with a Next-to-Leading-Order perturbative Quantum Chromodynamics calculation, obtained with the POWHEG method and interfaced with PYTHIA 6 for the generation of the parton shower, fragmentation, hadronisation and underlying event.
A measurement of beauty hadron production at mid-rapidity in proton-lead collisions at a nucleon-nucleon centre-of-mass energy sNN−−−√=5.02 TeV is presented. The semi-inclusive decay channel of beauty hadrons into J/ψ is considered, where the J/ψ mesons are reconstructed in the dielectron decay channel at mid-rapidity down to transverse momenta of 1.3 GeV/c. The bb¯¯¯ production cross section at mid-rapidity, dσbb¯¯¯/dy, and the total cross section extrapolated over full phase space, σbb¯¯¯, are obtained. This measurement is combined with results on inclusive J/ψ production to determine the prompt J/ψ cross sections. The results in p-Pb collisions are then scaled to expectations from pp collisions at the same centre-of-mass energy to derive the nuclear modification factor RpPb, and compared to models to study possible nuclear modifications of the production induced by cold nuclear matter effects. RpPb is found to be smaller than unity at low pT for both J/ψ coming from beauty hadron decays and prompt J/ψ.
Neutral pion and η meson invariant differential yields were measured in non-single diffractive p-Pb collisions at sNN−−−√=5.02 TeV with the ALICE experiment at the CERN LHC. The analysis combines results from three complementary photon measurements, utilizing the PHOS and EMCal calorimeters and the Photon Conversion Method. The invariant differential yields of π0 and η meson inclusive production are measured near mid-rapidity in a broad transverse momentum range of 0.3<pT<20 GeV/c and 0.7<pT<20 GeV/c, respectively. The measured η/π0 ratio increases with pT and saturates for pT>4 GeV/c at 0.483±0.015stat±0.015sys. A deviation from mT scaling is observed for pT<2 GeV/c. The measured η/π0 ratio is consistent with previous measurements from proton-nucleus and pp collisions over the full pT range. The measured η/π0 ratio at high pT also agrees within uncertainties with measurements from nucleus-nucleus collisions. The π0 and η yields in p-Pb relative to the scaled pp interpolated reference, RpPb, are presented for 0.3<pT<20 GeV/c and 0.7<pT<20 GeV/c, respectively. The results are compared with theoretical model calculations. The values of RpPb are consistent with unity for transverse momenta above 2 GeV/c. These results support the interpretation that the suppressed yield of neutral mesons measured in Pb-Pb collisions at LHC energies is due to parton energy loss in the hot QCD medium.
Neutral pion and η meson invariant differential yields were measured in non-single diffractive p-Pb collisions at sNN−−−√=5.02 TeV with the ALICE experiment at the CERN LHC. The analysis combines results from three complementary photon measurements, utilizing the PHOS and EMCal calorimeters and the Photon Conversion Method. The invariant differential yields of π0 and η meson inclusive production are measured near mid-rapidity in a broad transverse momentum range of 0.3<pT<20 GeV/c and 0.7<pT<20 GeV/c, respectively. The measured η/π0 ratio increases with pT and saturates for pT>4 GeV/c at 0.483±0.015stat±0.015sys. A deviation from mT scaling is observed for pT<2 GeV/c. The measured η/π0 ratio is consistent with previous measurements from proton-nucleus and pp collisions over the full pT range. The measured η/π0 ratio at high pT also agrees within uncertainties with measurements from nucleus-nucleus collisions. The π0 and η yields in p-Pb relative to the scaled pp interpolated reference, RpPb, are presented for 0.3<pT<20 GeV/c and 0.7<pT<20 GeV/c, respectively. The results are compared with theoretical model calculations. The values of RpPb are consistent with unity for transverse momenta above 2 GeV/c. These results support the interpretation that the suppressed yield of neutral mesons measured in Pb-Pb collisions at LHC energies is due to parton energy loss in the hot QCD medium.
Neutral pion and η meson production in the transverse momentum range 1 < pT < 20 GeV/c have been measured at mid-rapidity by the ALICE experiment at the Large Hadron Collider (LHC) in central and semi-central Pb-Pb collisions at sNN−−−−√ = 2.76 TeV. These results were obtained using the photon conversion method as well as the PHOS and EMCal detectors. The results extend the upper pT reach of the previous ALICE π0 measurements from 12 GeV/c to 20 GeV/c and present the first measurement of η meson production in heavy-ion collisions at the LHC. The η/π0 ratio is similar for the two centralities and reaches at high pT a plateau value of 0.457 ± 0.013stat ± 0.018syst. A suppression of similar magnitude for π0 and η meson production is observed in Pb-Pb collisions with respect to their production in pp collisions scaled by the number of binary nucleon-nucleon collisions. We discuss the results in terms of NLO pQCD predictions and hydrodynamic models. The measurements show a stronger suppression with respect to what was observed at lower center-of-mass energies in the pT range 6 < pT < 10 GeV/c. At pT < 3 GeV/c, hadronization models describe the π0 results while for the η some tension is observed.
Neutral pion and η meson production in the transverse momentum range 1 < pT < 20 GeV/c have been measured at mid-rapidity by the ALICE experiment at the Large Hadron Collider (LHC) in central and semi-central Pb-Pb collisions at sNN−−−−√ = 2.76 TeV. These results were obtained using the photon conversion method as well as the PHOS and EMCal detectors. The results extend the upper pT reach of the previous ALICE π0 measurements from 12 GeV/c to 20 GeV/c and present the first measurement of η meson production in heavy-ion collisions at the LHC. The η/π0 ratio is similar for the two centralities and reaches at high pT a plateau value of 0.457 ± 0.013stat ± 0.018syst. A suppression of similar magnitude for π0 and η meson production is observed in Pb-Pb collisions with respect to their production in pp collisions scaled by the number of binary nucleon-nucleon collisions. We discuss the results in terms of NLO pQCD predictions and hydrodynamic models. The measurements show a stronger suppression with respect to what was observed at lower center-of-mass energies in the pT range 6 < pT < 10 GeV/c. At pT < 3 GeV/c, hadronization models describe the π0 results while for the η some tension is observed.
Neutral pion and η meson production in the transverse momentum range 1 < pT < 20 GeV/c have been measured at mid-rapidity by the ALICE experiment at the Large Hadron Collider (LHC) in central and semi-central Pb-Pb collisions at sNN−−−−√ = 2.76 TeV. These results were obtained using the photon conversion method as well as the PHOS and EMCal detectors. The results extend the upper pT reach of the previous ALICE π0 measurements from 12 GeV/c to 20 GeV/c and present the first measurement of η meson production in heavy-ion collisions at the LHC. The η/π0 ratio is similar for the two centralities and reaches at high pT a plateau value of 0.457 ± 0.013stat ± 0.018syst. A suppression of similar magnitude for π0 and η meson production is observed in Pb-Pb collisions with respect to their production in pp collisions scaled by the number of binary nucleon-nucleon collisions. We discuss the results in terms of NLO pQCD predictions and hydrodynamic models. The measurements show a stronger suppression with respect to what was observed at lower center-of-mass energies in the pT range 6 < pT < 10 GeV/c. At pT < 3 GeV/c, hadronization models describe the π0 results while for the η some tension is observed.
Measurements of inclusive and direct photon production at mid-rapidity in pp collisions at s√=2.76 and 8 TeV are presented by the ALICE experiment at the LHC. The results are reported in transverse momentum ranges of 0.4<pT<10 GeV/c and 0.3<pT<16 GeV/c, respectively. Photons are detected with the electromagnetic calorimeter~(EMCal) and via reconstruction of e+e− pairs from conversions in the ALICE detector material using the central tracking system. For the final measurement of the inclusive photon spectra the results are combined in the overlapping pT interval of both methods. Direct photon spectra, or their upper limits at 90% C.L. are extracted using the direct photon excess ratio Rγ, which quantifies the ratio of inclusive photons over decay photons generated with a decay-photon simulation. An additional hybrid method, combining photons reconstructed from conversions with those identified in the EMCal, is used for the combination of the direct photon excess ratio Rγ, as well as the extraction of direct photon spectra or their upper limits. While no significant signal of direct photons is seen over the full pT range, Rγ for pT>7 GeV/c is at least one σ above unity and consistent with expectations from next-to-leading order pQCD calculations.
Measurements of inclusive and direct photon production at mid-rapidity in pp collisions at s√=2.76 and 8 TeV are presented by the ALICE experiment at the LHC. The results are reported in transverse momentum ranges of 0.4<pT<10 GeV/c and 0.3<pT<16 GeV/c, respectively. Photons are detected with the electromagnetic calorimeter~(EMCal) and via reconstruction of e+e− pairs from conversions in the ALICE detector material using the central tracking system. For the final measurement of the inclusive photon spectra the results are combined in the overlapping pT interval of both methods. Direct photon spectra, or their upper limits at 90% C.L. are extracted using the direct photon excess ratio Rγ, which quantifies the ratio of inclusive photons over decay photons generated with a decay-photon simulation. An additional hybrid method, combining photons reconstructed from conversions with those identified in the EMCal, is used for the combination of the direct photon excess ratio Rγ, as well as the extraction of direct photon spectra or their upper limits. While no significant signal of direct photons is seen over the full pT range, Rγ for pT>7 GeV/c is at least one σ above unity and consistent with expectations from next-to-leading order pQCD calculations.
Measurements of inclusive and direct photon production at mid-rapidity in pp collisions at s√=2.76 and 8 TeV are presented by the ALICE experiment at the LHC. The results are reported in transverse momentum ranges of 0.4<pT<10 GeV/c and 0.3<pT<16 GeV/c, respectively. Photons are detected with the electromagnetic calorimeter~(EMCal) and via reconstruction of e+e− pairs from conversions in the ALICE detector material using the central tracking system. For the final measurement of the inclusive photon spectra the results are combined in the overlapping pT interval of both methods. Direct photon spectra, or their upper limits at 90% C.L. are extracted using the direct photon excess ratio Rγ, which quantifies the ratio of inclusive photons over decay photons generated with a decay-photon simulation. An additional hybrid method, combining photons reconstructed from conversions with those identified in the EMCal, is used for the combination of the direct photon excess ratio Rγ, as well as the extraction of direct photon spectra or their upper limits. While no significant signal of direct photons is seen over the full pT range, Rγ for pT>7 GeV/c is at least one σ above unity and consistent with expectations from next-to-leading order pQCD calculations.
Transverse-momentum (pT) differential yields of electrons from semileptonic heavy-flavour hadron decays have been measured in the most central (0-10%) and in semi-central (20-40%) Pb-Pb collisions at sNN−−−√=2.76 TeV. The corresponding production cross section in pp collisions has been measured at the same energy with substantially reduced systematic uncertainties with respect to previously published results. The modification of the yield in Pb-Pb collisions with respect to the expectation from an incoherent superposition of nucleon-nucleon collisions is quantified at mid-rapidity (|y| < 0.8) in the pT interval 0.5-3 GeV/c via the nuclear modification factor, RAA. This paper extends the pT reach of the RAA measurement towards significantly lower values with respect to a previous publication. In Pb-Pb collisions the pT-differential measurements of yields at low pT are essential to investigate the scaling of heavy-flavour production with the number of binary nucleon-nucleon collisions. Heavy-quark hadronization, a collective expansion and even initial-state effects, such as the nuclear modification of the Parton Distribution Functions, are also expected to have a significant effect on the measured distribution.
Transverse-momentum (pT) differential yields of electrons from semileptonic heavy-flavour hadron decays have been measured in the most central (0-10%) and in semi-central (20-40%) Pb-Pb collisions at sNN−−−√=2.76 TeV. The corresponding production cross section in pp collisions has been measured at the same energy with substantially reduced systematic uncertainties with respect to previously published results. The modification of the yield in Pb-Pb collisions with respect to the expectation from an incoherent superposition of nucleon-nucleon collisions is quantified at mid-rapidity (|y| < 0.8) in the pT interval 0.5-3 GeV/c via the nuclear modification factor, RAA. This paper extends the pT reach of the RAA measurement towards significantly lower values with respect to a previous publication. In Pb-Pb collisions the pT-differential measurements of yields at low pT are essential to investigate the scaling of heavy-flavour production with the number of binary nucleon-nucleon collisions. Heavy-quark hadronization, a collective expansion and even initial-state effects, such as the nuclear modification of the Parton Distribution Functions, are also expected to have a significant effect on the measured distribution.
Inclusive J/ψ production is studied in p-Pb interactions at a centre-of-mass energy per nucleon-nucleon collision sNN−−−√=8.16 TeV, using the ALICE detector at the CERN LHC. The J/ψ meson is reconstructed, via its decay to a muon pair, in the centre-of-mass rapidity intervals 2.03<ycms<3.53 and −4.46<ycms<−2.96, where positive and negative ycms refer to the p-going and Pb-going direction, respectively. The transverse momentum coverage is pT<20 GeV/c. In this paper, ycms- and pT-differential cross sections for inclusive J/ψ production are presented, and the corresponding nuclear modification factors RpPb are shown. Forward results show a suppression of the J/ψ yield with respect to pp collisions, concentrated in the region pT≲5 GeV/c. At backward rapidity no significant suppression is observed. The results are compared to previous measurements by ALICE in p-Pb collisions at sNN−−−√=5.02 TeV and to theoretical calculations. Finally, the ratios RFB between forward- and backward-ycms RpPb values are shown and discussed.
Inclusive J/ψ production is studied in p-Pb interactions at a centre-of-mass energy per nucleon-nucleon collision sNN−−−√=8.16 TeV, using the ALICE detector at the CERN LHC. The J/ψ meson is reconstructed, via its decay to a muon pair, in the centre-of-mass rapidity intervals 2.03<ycms<3.53 and −4.46<ycms<−2.96, where positive and negative ycms refer to the p-going and Pb-going direction, respectively. The transverse momentum coverage is pT<20 GeV/c. In this paper, ycms- and pT-differential cross sections for inclusive J/ψ production are presented, and the corresponding nuclear modification factors RpPb are shown. Forward results show a suppression of the J/ψ yield with respect to pp collisions, concentrated in the region pT≲5 GeV/c. At backward rapidity no significant suppression is observed. The results are compared to previous measurements by ALICE in p-Pb collisions at sNN−−−√=5.02 TeV and to theoretical calculations. Finally, the ratios RFB between forward- and backward-ycms RpPb values are shown and discussed.
The first measurement of e+e− pair production at mid-rapidity (|ηe| < 0.8) in pp collisions at s√=7 TeV with ALICE at the LHC is presented. The dielectron production is studied as a function of the invariant mass (mee < 3.3 GeV/c2), the pair transverse momentum (pT,ee < 8 GeV/c), and the pair transverse impact parameter (DCAee), i.e., the average distance of closest approach of the reconstructed electron and positron tracks to the collision vertex, normalised to its resolution. The results are compared with the expectations from a cocktail of known hadronic sources and are well described when PYTHIA is used to generate the heavy-flavour contributions. In the low-mass region (0.14 < mee < 1.1 GeV/c2), prompt and non-prompt e+e− sources can be separated via the DCAee. In the intermediate-mass region (1.1 < mee < 2.7 GeV/c2), a double-differential fit to the data in mee and pT,ee and a fit of the DCAee distribution allow the total cc¯¯ and bb¯¯¯ cross sections to be extracted. Two different event generators, PYTHIA and POWHEG, can reproduce the shape of the two-dimensional mee and pT,ee spectra, as well as the shape of the DCAee distribution, reasonably well. However, differences in the cc¯¯ and bb¯¯¯ cross sections are observed when using the generators to extrapolate to full phase space. Finally, the ratio of inclusive to decay photons is studied via the measurement of virtual direct photons in the transverse-momentum range 1 < pT < 8 GeV/c. This is found to be unity within the statistical and systematic uncertainties and consistent with expectations from next-to-leading order perturbative quantum chromodynamic calculations.
The production of the ρ(770)0 meson has been measured at mid-rapidity (|y|<0.5) in pp and centrality differential Pb-Pb collisions at sNN−−−√ = 2.76 TeV with the ALICE detector at the Large Hadron Collider. The particles have been reconstructed in the ρ(770)→π+π− decay channel in the transverse momentum (pT) range 0.5−11 GeV/c. A centrality dependent suppression of the ratio of the integrated yields 2ρ(770)0/(π++π−) is observed. The ratio decreases by ∼40% from pp to central Pb-Pb collisions. A study of the pT-differential 2ρ(770)0/(π++π−) ratio reveals that the suppression occurs at low transverse momenta, pT<2 GeV/c. At higher momentum, particle ratios measured in heavy-ion and pp collisions are consistent. The observed suppression is very similar to that previously measured for the K∗(892)0/K ratio and is consistent with EPOS3 predictions that may imply that rescattering in the hadronic phase is a dominant mechanism for the observed suppression.
The production of the ρ(770)0 meson has been measured at mid-rapidity (|y|<0.5) in pp and centrality differential Pb-Pb collisions at sNN−−−√ = 2.76 TeV with the ALICE detector at the Large Hadron Collider. The particles have been reconstructed in the ρ(770)→π+π− decay channel in the transverse momentum (pT) range 0.5−11 GeV/c. A centrality dependent suppression of the ratio of the integrated yields 2ρ(770)0/(π++π−) is observed. The ratio decreases by ∼40% from pp to central Pb-Pb collisions. A study of the pT-differential 2ρ(770)0/(π++π−) ratio reveals that the suppression occurs at low transverse momenta, pT<2 GeV/c. At higher momentum, particle ratios measured in heavy-ion and pp collisions are consistent. The observed suppression is very similar to that previously measured for the K∗(892)0/K ratio and is consistent with EPOS3 predictions that may imply that rescattering in the hadronic phase is a dominant mechanism for the observed suppression.
The production of the ρ(770)0 meson has been measured at mid-rapidity (|y|<0.5) in pp and centrality differential Pb-Pb collisions at sNN−−−√ = 2.76 TeV with the ALICE detector at the Large Hadron Collider. The particles have been reconstructed in the ρ(770)→π+π− decay channel in the transverse momentum (pT) range 0.5−11 GeV/c. A centrality dependent suppression of the ratio of the integrated yields 2ρ(770)0/(π++π−) is observed. The ratio decreases by ∼40% from pp to central Pb-Pb collisions. A study of the pT-differential 2ρ(770)0/(π++π−) ratio reveals that the suppression occurs at low transverse momenta, pT<2 GeV/c. At higher momentum, particle ratios measured in heavy-ion and pp collisions are consistent. The observed suppression is very similar to that previously measured for the K∗(892)0/K ratio and is consistent with EPOS3 predictions that may imply that rescattering in the hadronic phase is a dominant mechanism for the observed suppression.
Inclusive J/ψ production is studied in Xe-Xe interactions at a centre-of-mass energy per nucleon pair of sNN−−−√=5.44 TeV, using the ALICE detector at the CERN LHC. The J/ψ meson is reconstructed via its decay into a muon pair, in the centre-of-mass rapidity interval 2.5<y<4 and down to zero transverse momentum. In this Letter, the nuclear modification factors RAA for inclusive J/ψ, measured in the centrality range 0-90% as well as in the centrality intervals 0-20% and 20-90% are presented. The RAA values are compared to previously published results for Pb-Pb collisions at sNN−−−√=5.02 TeV and to the calculation of a transport model. A good agreement is found between Xe-Xe and Pb-Pb results as well as between data and the model.
Inclusive J/ψ production is studied in Xe-Xe interactions at a centre-of-mass energy per nucleon pair of sNN−−−√=5.44 TeV, using the ALICE detector at the CERN LHC. The J/ψ meson is reconstructed via its decay into a muon pair, in the centre-of-mass rapidity interval 2.5<y<4 and down to zero transverse momentum. In this Letter, the nuclear modification factors RAA for inclusive J/ψ, measured in the centrality range 0-90% as well as in the centrality intervals 0-20% and 20-90% are presented. The RAA values are compared to previously published results for Pb-Pb collisions at sNN−−−√=5.02 TeV and to the calculation of a transport model. A good agreement is found between Xe-Xe and Pb-Pb results as well as between data and the model.
Transverse momentum (pT) spectra of charged particles at mid-pseudorapidity in Xe-Xe collisions at sNN−−−√ = 5.44 TeV measured with the ALICE apparatus at the Large Hadron Collider are reported. The kinematic range 0.15<pT<50 GeV/c and |η|<0.8 is covered. Results are presented in nine classes of collision centrality in the 0-80% range. For comparison, a pp reference at the collision energy of s√ = 5.44 TeV is obtained by interpolating between existing \pp measurements at s√ = 5.02 and 7 TeV. The nuclear modification factors in central Xe-Xe collisions and Pb-Pb collisions at a similar center-of-mass energy of sNN−−−√ = 5.02 TeV, and in addition at 2.76 TeV, at analogous ranges of charged particle multiplicity density ⟨dNch/dη⟩ show a remarkable similarity at pT>10 GeV/c. The comparison of the measured RAA values in the two colliding systems could provide insight on the path length dependence of medium-induced parton energy loss. The centrality dependence of the ratio of the average transverse momentum ⟨pT⟩ in Xe-Xe collisions over Pb-Pb collision at s√ = 5.02 TeV is compared to hydrodynamical model calculations.
Inclusive Υ(1S) and Υ(2S) production have been measured in Pb-Pb collisions at the centre-of-mass energy per nucleon-nucleon pair sNN−−−√=5.02 TeV, using the ALICE detector at the CERN LHC. The Υ mesons are reconstructed in the centre-of-mass rapidity interval 2.5<y<4 and in the transverse-momentum range pT<15 GeV/c, via their decays to muon pairs. In this Letter, we present results on the inclusive Υ(1S) nuclear modification factor RAA as a function of collision centrality, transverse momentum and rapidity. The Υ(1S) and Υ(2S) RAA, integrated over the centrality range 0-90%, are 0.37±0.02(stat)±0.03(syst) and 0.10±0.04(stat)±0.02(syst), respectively, leading to a ratio RΥ(2S)AA/RΥ(1S)AA of 0.28±0.12(stat)±0.06(syst). The observed Υ(1S) suppression increases with the centrality of the collision and no significant variation is observed as a function of transverse momentum and rapidity.
Transverse momentum (pT) spectra of charged particles at mid-pseudorapidity in Xe-Xe collisions at sNN−−−√ = 5.44 TeV measured with the ALICE apparatus at the Large Hadron Collider are reported. The kinematic range 0.15<pT<50 GeV/c and |η|<0.8 is covered. Results are presented in nine classes of collision centrality in the 0-80% range. For comparison, a pp reference at the collision energy of s√ = 5.44 TeV is obtained by interpolating between existing \pp measurements at s√ = 5.02 and 7 TeV. The nuclear modification factors in central Xe-Xe collisions and Pb-Pb collisions at a similar center-of-mass energy of sNN−−−√ = 5.02 TeV, and in addition at 2.76 TeV, at analogous ranges of charged particle multiplicity density ⟨dNch/dη⟩ show a remarkable similarity at pT>10 GeV/c. The centrality dependence of the ratio of the average transverse momentum ⟨pT⟩ in Xe-Xe collisions over Pb-Pb collision at s√ = 5.02 TeV is compared to hydrodynamical model calculations.
Inclusive Υ(1S) and Υ(2S) production have been measured in Pb-Pb collisions at the centre-of-mass energy per nucleon-nucleon pair sNN−−−√=5.02 TeV, using the ALICE detector at the CERN LHC. The Υ mesons are reconstructed in the centre-of-mass rapidity interval 2.5<y<4 and in the transverse-momentum range pT<15 GeV/c, via their decays to muon pairs. In this Letter, we present results on the inclusive Υ(1S) nuclear modification factor RAA as a function of collision centrality, transverse momentum and rapidity. The Υ(1S) and Υ(2S) RAA, integrated over the centrality range 0-90%, are 0.37±0.02(stat)±0.03(syst) and 0.10±0.04(stat)±0.02(syst), respectively, leading to a ratio RΥ(2S)AA/RΥ(1S)AA of 0.28±0.12(stat)±0.06(syst). The observed Υ(1S) suppression increases with the centrality of the collision and no significant variation is observed as a function of transverse momentum and rapidity.
Charged-particle spectra at midrapidity are measured in Pb-Pb collisions at the centre-of-mass energy per nucleon-nucleon pair sNN−−−√ = 5.02 TeV and presented in centrality classes ranging from most central (0-5%) to most peripheral (95-100%) collisions. Possible medium effects are quantified using the nuclear modification factor (RAA) by comparing the measured spectra with those from proton-proton collisions, scaled by the number of independent nucleon-nucleon collisions obtained from a Glauber model. At large transverse momenta (8<pT<20 GeV/c), the average RAA is found to increase from about 0.15 in 0-5% central to a maximum value of about 0.8 in 75-85% peripheral collisions, beyond which it falls off strongly to below 0.2 for the most peripheral collisions. Furthermore, RAA initially exhibits a positive slope as a function of pT in the 8-20 GeV/c interval, while for collisions beyond the 80% class the slope is negative. To reduce uncertainties related to event selection and normalization, we also provide the ratio of RAA in adjacent centrality intervals. Our results in peripheral collisions are consistent with a PYTHIA-based model without nuclear modification, demonstrating that biases caused by the event selection and collision geometry can lead to the apparent suppression in peripheral collisions. This explains the unintuitive observation that RAA is below unity in peripheral Pb-Pb, but equal to unity in minimum-bias p-Pb collisions despite similar charged-particle multiplicities.
Charged-particle spectra at midrapidity are measured in Pb-Pb collisions at the centre-of-mass energy per nucleon-nucleon pair sNN−−−√ = 5.02 TeV and presented in centrality classes ranging from most central (0-5%) to most peripheral (95-100%) collisions. Possible medium effects are quantified using the nuclear modification factor (RAA) by comparing the measured spectra with those from proton-proton collisions, scaled by the number of independent nucleon-nucleon collisions obtained from a Glauber model. At large transverse momenta (8<pT<20 GeV/c), the average RAA is found to increase from about 0.15 in 0-5% central to a maximum value of about 0.8 in 75-85% peripheral collisions, beyond which it falls off strongly to below 0.2 for the most peripheral collisions. Furthermore, RAA initially exhibits a positive slope as a function of pT in the 8-20 GeV/c interval, while for collisions beyond the 80% class the slope is negative. To reduce uncertainties related to event selection and normalization, we also provide the ratio of RAA in adjacent centrality intervals. Our results in peripheral collisions are consistent with a PYTHIA-based model without nuclear modification, demonstrating that biases caused by the event selection and collision geometry can lead to the apparent suppression in peripheral collisions. This explains the unintuitive observation that RAA is below unity in peripheral Pb-Pb, but equal to unity in minimum-bias p-Pb collisions despite similar charged-particle multiplicities.
The production yield of the Λ(1520) baryon resonance is measured at mid-rapidity in Pb-Pb collisions at sNN−−−√ = 2.76 TeV with the ALICE detector at the LHC. The measurement is performed in the Λ(1520)→pK− (and charge conjugate) hadronic decay channel as a function of the transverse momentum (pT) and collision centrality. The pT-integrated production rate of Λ(1520) relative to Λ in central collisions is suppressed by about a factor of 2 with respect to peripheral collisions. This is the first observation of the suppression of a baryonic resonance at LHC and the first evidence of Λ(1520) suppression in heavy-ion collisions. The measured Λ(1520)/Λ ratio in central collisions is smaller than the value predicted by the statistical hadronisation model calculations. The shape of the measured pT distribution and the centrality dependence of the suppression are reproduced by the EPOS3 Monte Carlo event generator. The measurement adds further support to the formation of a dense hadronic phase in the final stages of the evolution of the fireball created in heavy-ion collisions, lasting long enough to cause a significant reduction in the observable yield of short-lived resonances.
The production yield of the Λ(1520) baryon resonance is measured at mid-rapidity in Pb-Pb collisions at sNN−−−√ = 2.76 TeV with the ALICE detector at the LHC. The measurement is performed in the Λ(1520)→pK− (and charge conjugate) hadronic decay channel as a function of the transverse momentum (pT) and collision centrality. The pT-integrated production rate of Λ(1520) relative to Λ in central collisions is suppressed by about a factor of 2 with respect to peripheral collisions. This is the first observation of the suppression of a baryonic resonance at the LHC and the first 3σ evidence of Λ(1520) suppression within a single collision system. The measured Λ(1520)/Λ ratio in central collisions is smaller than the value predicted by the statistical hadronisation model calculations. The shape of the measured pT distribution and the centrality dependence of the suppression are reproduced by the EPOS3 Monte Carlo event generator. The measurement adds further support to the formation of a dense hadronic phase in the final stages of the evolution of the fireball created in heavy-ion collisions, lasting long enough to cause a significant reduction in the observable yield of short-lived resonances.
The production yield of the Λ(1520) baryon resonance is measured at mid-rapidity in Pb-Pb collisions at sNN−−−√ = 2.76 TeV with the ALICE detector at the LHC. The measurement is performed in the Λ(1520)→pK− (and charge conjugate) hadronic decay channel as a function of the transverse momentum (pT) and collision centrality. The pT-integrated production rate of Λ(1520) relative to Λ in central collisions is suppressed by about a factor of 2 with respect to peripheral collisions. This is the first observation of the suppression of a baryonic resonance at the LHC and the first 3σ evidence of Λ(1520) suppression within a single collision system. The measured Λ(1520)/Λ ratio in central collisions is smaller than the value predicted by the statistical hadronisation model calculations. The shape of the measured pT distribution and the centrality dependence of the suppression are reproduced by the EPOS3 Monte Carlo event generator. The measurement adds further support to the formation of a dense hadronic phase in the final stages of the evolution of the fireball created in heavy-ion collisions, lasting long enough to cause a significant reduction in the observable yield of short-lived resonances.
The elliptic flow of inclusive and direct photons was measured at mid-rapidity in two centrality classes 0-20% and 20-40% in Pb-Pb collisions at sNN−−−√ = 2.76 TeV by ALICE. Photons were detected with the highly segmented electromagnetic calorimeter PHOS and via conversions in the detector material with the e+e− pairs reconstructed in the central tracking system. The results of the two methods were combined and the direct photon elliptic flow was extracted in the transverse momentum range 0.9<pT<6.2 GeV/c. A comparison to RHIC data shows a similar magnitude of the measured direct-photon elliptic flow. Hydrodynamic and transport model calculations are systematically lower than the data, but are found to be compatible.
The elliptic flow of inclusive and direct photons was measured at mid-rapidity in two centrality classes 0-20% and 20-40% in Pb-Pb collisions at sNN−−−√ =2.76 TeV by ALICE. Photons were detected with the highly segmented electromagnetic calorimeter PHOS and via conversions in the detector material with the e+e− pairs reconstructed in the central tracking system. The results of the two methods were combined and the direct photon elliptic flow was extracted in the transverse momentum range 0.9<pT<6.2 GeV/c. We test the hypothesis vγ,dir2≡0 for 0.9<pT<2.1 GeV/c and obtain a significance of 1.4σ for the 0-20% class and 1.0σ for the 20-40% class. A comparison to RHIC data shows a similar magnitude of the measured elliptic flow, while hydrodynamic and transport model calculations predict a smaller flow than observed.
We present measurements of two-particle differential number correlation functions R2 and transverse momentum correlation functions P2, obtained from p-Pb collisions at 5.02 TeV and Pb-Pb collisions at 2.76 TeV. The results are obtained using charged particles in the pseudorapidity range |η|< 1.0, and transverse momentum range 0.2<pT<2.0 GeV/c as a function of pair separation in pseudorapidity, |Δη|, azimuthal angle, Δφ, and for several charged-particle multiplicity classes. Measurements are carried out for like-sign and unlike-sign charged-particle pairs separately and combined to obtain charge-independent and charge-dependent correlation functions. We study the evolution of the width of the near-side peak of these correlation functions with collision centrality. Additionally, we study Fourier decompositions of the correlators in Δφ as a function of the pair separation |Δη|. Significant differences in the dependence of their harmonic coefficients on multiplicity classes are found. These differences can be exploited, in theoretical models, to obtain further insight into charged-particle production and transport in heavy-ion collisions. Moreover, an upper limit of non-flow contributions to flow coefficients vn measured in Pb-Pb collisions based on the relative strength of Fourier coefficients measured in p-Pb interactions is estimated.
Measurements of charged-particle production in pp, p−Pb, and Pb−Pb collisions in the toward, away, and transverse regions with the ALICE detector are discussed. These regions are defined event-by-event relative to the azimuthal direction of the charged trigger particle, which is the reconstructed particle with the largest transverse momentum (ptrigT) in the range 8<ptrigT<15 GeV/c. The toward and away regions contain the primary and recoil jets, respectively; both regions are accompanied by the underlying event (UE). In contrast, the transverse region perpendicular to the direction of the trigger particle is dominated by the so-called UE dynamics, and includes also contributions from initial- and final-state radiation. The relative transverse activity classifier, RT=NTch/⟨NTch⟩, is used to group events according to their UE activity, where NTch is the charged-particle multiplicity per event in the transverse region and ⟨NTch⟩ is the mean value over the whole analysed sample. The energy dependence of the RT distributions in pp collisions at s√=2.76, 5.02, 7, and 13 TeV is reported, exploring the Koba-Nielsen-Olesen (KNO) scaling properties of the multiplicity distributions. The first measurements of charged-particle pT spectra as a function of RT in the three azimuthal regions in pp, p−Pb, and Pb−Pb collisions at sNN−−−√=5.02 TeV are also reported. Data are compared with predictions obtained from the event generators PYTHIA 8 and EPOS LHC. This set of measurements is expected to contribute to the understanding of the origin of collective-like effects in small collision systems (pp and p−Pb).
Measurements of charged-particle production in pp, p−Pb, and Pb−Pb collisions in the toward, away, and transverse regions with the ALICE detector are discussed. These regions are defined event-by-event relative to the azimuthal direction of the charged trigger particle, which is the reconstructed particle with the largest transverse momentum (ptrigT) in the range 8<ptrigT<15 GeV/c. The toward and away regions contain the primary and recoil jets, respectively; both regions are accompanied by the underlying event (UE). In contrast, the transverse region perpendicular to the direction of the trigger particle is dominated by the so-called UE dynamics, and includes also contributions from initial- and final-state radiation. The relative transverse activity classifier, RT=NTch/⟨NTch⟩, is used to group events according to their UE activity, where NTch is the charged-particle multiplicity per event in the transverse region and ⟨NTch⟩ is the mean value over the whole analysed sample. The energy dependence of the RT distributions in pp collisions at s√=2.76, 5.02, 7, and 13 TeV is reported, exploring the Koba-Nielsen-Olesen (KNO) scaling properties of the multiplicity distributions. The first measurements of charged-particle pT spectra as a function of RT in the three azimuthal regions in pp, p−Pb, and Pb−Pb collisions at sNN−−−√=5.02 TeV are also reported. Data are compared with predictions obtained from the event generators PYTHIA 8 and EPOS LHC. This set of measurements is expected to contribute to the understanding of the origin of collective-like effects in small collision systems (pp and p−Pb).
The Chiral Magnetic Wave (CMW) phenomenon is essential to provide insights into the strong interaction in QCD, the properties of the quark-gluon plasma, and the topological characteristics of the early universe, offering a deeper understanding of fundamental physics in high-energy collisions. Measurements of the charge-dependent anisotropic flow coefficients are studied in Pb-Pb collisions at center-of-mass energy per nucleon-nucleon collision sNN−−−√= 5.02 TeV to probe the CMW. In particular, the slope of the normalized difference in elliptic (v2) and triangular (v3) flow coefficients of positively and negatively charged particles as a function of their event-wise normalized number difference, is reported for inclusive and identified particles. The slope rNorm3 is found to be larger than zero and to have a magnitude similar to rNorm2, thus pointing to a large background contribution for these measurements. Furthermore, rNorm2 can be described by a blast wave model calculation that incorporates local charge conservation. In addition, using the event shape engineering technique yields a fraction of CMW (fCMW) contribution to this measurement which is compatible with zero. This measurement provides the very first upper limit for fCMW, and in the 10-60% centrality interval it is found to be 26% (38%) at 95% (99.7%) confidence level.
The Chiral Magnetic Wave (CMW) phenomenon is essential to provide insights into the strong interaction in QCD, the properties of the quark-gluon plasma, and the topological characteristics of the early universe, offering a deeper understanding of fundamental physics in high-energy collisions. Measurements of the charge-dependent anisotropic flow coefficients are studied in Pb-Pb collisions at center-of-mass energy per nucleon-nucleon collision sNN−−−√= 5.02 TeV to probe the CMW. In particular, the slope of the normalized difference in elliptic (v2) and triangular (v3) flow coefficients of positively and negatively charged particles as a function of their event-wise normalized number difference, is reported for inclusive and identified particles. The slope rNorm3 is found to be larger than zero and to have a magnitude similar to rNorm2, thus pointing to a large background contribution for these measurements. Furthermore, rNorm2 can be described by a blast wave model calculation that incorporates local charge conservation. In addition, using the event shape engineering technique yields a fraction of CMW (fCMW) contribution to this measurement which is compatible with zero. This measurement provides the very first upper limit for fCMW, and in the 10-60% centrality interval it is found to be 26% (38%) at 95% (99.7%) confidence level.
Long- and short-range correlations for pairs of charged particles are studied via two-particle angular correlations in pp collisions at s√=13 TeV and p−Pb collisions at sNN−−−√=5.02 TeV. The correlation functions are measured as a function of relative azimuthal angle Δφ and pseudorapidity separation Δη for pairs of primary charged particles within the pseudorapidity interval |η|<0.9 and the transverse-momentum interval 1<pT<4 GeV/c. Flow coefficients are extracted for the long-range correlations (1.6<|Δη|<1.8) in various high-multiplicity event classes using the low-multiplicity template fit method. The method is used to subtract the enhanced yield of away-side jet fragments in high-multiplicity events. These results show decreasing flow signals toward lower multiplicity events. Furthermore, the flow coefficients for events with hard probes, such as jets or leading particles, do not exhibit any significant changes compared to those obtained from high-multiplicity events without any specific event selection criteria. The results are compared with hydrodynamic-model calculations, and it is found that a better understanding of the initial conditions is necessary to describe the results, particularly for low-multiplicity events.
Long- and short-range correlations for pairs of charged particles are studied via two-particle angular correlations in pp collisions at √sNN = 13 TeV and p–Pb collisions at √s = 5.02 TeV. The correlation functions are measured as a function of relative azimuthal angle ∆φ and pseudorapidity separation ∆η for pairs of primary charged particles within the pseudorapidity interval |η| < 0.9 and the transverse-momentum interval 1 < pT < 4 GeV/c. Flow coefficients are extracted for the long-range correlations (1.6 < |∆η| < 1.8) in various high-multiplicity event classes using the low-multiplicity template fit method. The method is used to subtract the enhanced yield of away-side jet fragments in high-multiplicity events. These results show decreasing flow signals toward lower multiplicity events. Furthermore, the flow coefficients for events with hard probes, such as jets or leading particles, do not exhibit any significant changes compared to those obtained from high-multiplicity events without any specific event selection criteria. The results are compared with hydrodynamic-model calculations, and it is found that a better understanding of the initial conditions is necessary to describe the results, particularly for low-multiplicity events.