Refine
Year of publication
Language
- English (604)
Has Fulltext
- yes (604) (remove)
Is part of the Bibliography
- no (604)
Keywords
- BESIII (18)
- e +-e − Experiments (14)
- Branching fraction (10)
- LHC (9)
- Particle and Resonance Production (7)
- Quarkonium (7)
- Spectroscopy (6)
- Charm Physics (5)
- Hadronic decays (5)
- Heavy-ion collisions (5)
- ALICE experiment (4)
- Branching fractions (4)
- Charmonium (4)
- Exotics (4)
- Lepton colliders (4)
- ALICE (3)
- Charmed mesons (3)
- Diffraction (3)
- Elastic scattering (3)
- Electroweak interaction (3)
- Experimental nuclear physics (3)
- Experimental particle physics (3)
- Initial state radiation (3)
- Polarization (3)
- e+-e− Experiments (3)
- pp collisions (3)
- Beam Energy Scan (2)
- Beauty production (2)
- Bhabha (2)
- Charm physics (2)
- Chiral Magnetic Effect (2)
- Collectivity (2)
- Correlation (2)
- Cross section (2)
- Electroweak Interaction (2)
- Elliptic flow (2)
- Flavour Physics (2)
- Hadronic cross section (2)
- Jets (2)
- Leptonic, semileptonic & radiative decays (2)
- Muon anomaly (2)
- Particle decays (2)
- Pb–Pb collisions (2)
- Pion form factor (2)
- QCD (2)
- Quark-Gluon Plasma (2)
- RHIC (2)
- Radiative decay (2)
- STAR (2)
- Shear viscosity (2)
- Single electrons (2)
- 900 GeV (1)
- ALICE detector (1)
- Absolute branching fraction (1)
- Angular distribution (1)
- Annihilation (1)
- Anti-nuclei (1)
- B-slope (1)
- BESIII detector (1)
- BRD4 (1)
- Beam energy scan (1)
- Born cross section (1)
- Born cross section measurement (1)
- Branching fraction measurement (1)
- CDK9 (1)
- COVID-19 (1)
- CP violation (1)
- Canonical suppression (1)
- Charged-particle multiplicity (1)
- Charm quark spatial diffusion coefficient (1)
- Charm vector (1)
- Charmonia (1)
- Charmonium (-like) (1)
- Chiral magnetic effect (1)
- Coalescence (1)
- Cold nuclear matter effects (1)
- Comparison with QCD (1)
- Covariance matrix (1)
- Critical point (1)
- Cross section measurements (1)
- D meson (1)
- D0 and D+ mesons (1)
- Dalitz decay (1)
- Dark photon (1)
- Dark sector (1)
- Data sharing (1)
- Deuteron production (1)
- Di-hadron correlations (1)
- D⁰ meson (1)
- Effective form factor (1)
- Electromagnetic amplitude (1)
- Electromagnetic form factor (1)
- Electromagnetic form factors (1)
- Electron-pion identification (1)
- Ewing sarcoma (1)
- FOS: Physical sciences (1)
- Femtoscopy (1)
- Fibre/foam sandwich radiator (1)
- Flavor changing neutral currents (1)
- Flavor symmetries (1)
- Flow (1)
- Form factors (1)
- Forward physics (1)
- Genetics (1)
- Groomed jet radius (1)
- HBT (1)
- Hadron production (1)
- Hadron-Hadron Scattering (1)
- Hadron-Hadron Scattering Heavy (1)
- Hadron-Hadron scattering (experiments) (1)
- Hadron-hadron interactions (1)
- Hadronization (1)
- Hadrons (1)
- Heavy Ion Experiment (1)
- Heavy Ion Experiments (1)
- Heavy Ions (1)
- Heavy Quark Production (1)
- Heavy flavor production (1)
- Heavy flavour production (1)
- Heavy ion collisions (1)
- Heavy-Ion Collision (1)
- Heavy-flavor decay electron (1)
- Heavy-flavour decay muons (1)
- Heavy-flavour production (1)
- Heavy-ion (1)
- Helicity amplitude analysis (1)
- High Energy Physics - Experiment (hep-ex) (1)
- Higher moments (1)
- Hyperons (1)
- Inclusive branching fraction (1)
- Inclusive spectra (1)
- Intensity interferometry (1)
- Interference fragmentation function (1)
- Invisible decays (1)
- Ionisation energy loss (1)
- J/ψ suppression (1)
- Jet substructure (1)
- Jets and Jet Substructure (1)
- K0S (1)
- Mid-rapidity (1)
- Molecular biology (1)
- Multi-strange baryons (1)
- Multi-wire proportional drift chamber (1)
- Multiple parton interactions (1)
- NMR spectroscopy (1)
- Net-charge correlations (1)
- Net-charge fluctuations (1)
- Neural network (1)
- Neutrinos (1)
- Nonflow (1)
- Nuclear modification factor (1)
- PYTHIA (1)
- Particle and resonance production (1)
- Particle phenomena (1)
- Particle production (1)
- Pb–Pb (1)
- Phase (1)
- Properties of Hadrons (1)
- Proton (1)
- Proton-proton collisions (1)
- Proton–proton (1)
- Proton–proton collisions (1)
- Quantum chromodynamics (1)
- Quark Production (1)
- Quark–gluon plasma (1)
- R value (1)
- Rare decays (1)
- Relativistic heavy-ion collisions (1)
- Resonances (1)
- SARS-CoV-2 (1)
- Semi-leptonic decays (1)
- Single muons (1)
- SoftDrop (1)
- Spin alignment (1)
- Splitting function (1)
- Strangeness enhancement (1)
- Strong amplitude (1)
- TR (1)
- Techniques Electromagnetic calorimeters (1)
- Thermal model (1)
- Threshold effect (1)
- Tracking (1)
- Transition radiation detector (1)
- Transverse momentum (1)
- Transversity (1)
- Trigger (1)
- Triple quarkonia (1)
- Vector Boson Production (1)
- W-exchange (1)
- Xenon-based gas mixture (1)
- Y (4260) (1)
- Y states (1)
- accessory proteins (1)
- alleles (1)
- autism spectrum disorder (1)
- autistic disorder (1)
- branching fractions (1)
- cell-free protein synthesis (1)
- center-of-mass energy (1)
- charmed baryon (1)
- charmonium-like states (1)
- combination therapy (1)
- copy number polymorphism (1)
- dE/dx (1)
- decay (1)
- decays (1)
- dimuon (1)
- diphoton (1)
- e+e − annihilation (1)
- e+e⁻ − Experiments (1)
- e+e− Experiments (1)
- e+e− annihilation (1)
- electron-positron collision (1)
- genes (1)
- genetics (1)
- genome (1)
- genotype (1)
- genotype determination (1)
- global change (1)
- habitat destruction (1)
- hadron spectroscopy (1)
- hadronic events (1)
- heavy-ion collisions (1)
- helicity amplitude analysis (1)
- inclusive J/ψ decays (1)
- intrinsically disordered region (1)
- land use (1)
- luminosity (1)
- nonstructural proteins (1)
- number of J/ψ events (1)
- p+p collisions (1)
- phenotype (1)
- single nucleotide polymorphism (1)
- spectra (1)
- structural proteins (1)
- tetraquark (1)
- trigger efficiency (1)
- tumor growth (1)
- Λ+c baryon (1)
- Λc⁺ (1)
- Σ hyperon (1)
- Υ suppression (1)
- ψ(3686) (1)
- √sN N = 2.76 TeV (1)
A measurement of the production of prompt +c baryons in Pb–Pb collisions at √sNN = 5.02 TeV with the ALICE detector at the LHC is reported. The +c and − c were reconstructed at midrapidity (|y| < 0.5) via the hadronic decay channel +c → pK0 S (and charge conjugate) in the transverse momentum and centrality intervals 6 < pT < 12 GeV/c and 0–80%. The +c /D0 ratio, which is sensitive to the charm quark hadronisation mechanisms in the medium, is measured and found to be larger than the ratio measured in minimum-bias pp collisions at √s = 7 TeV and in p–Pb collisions at √sNN = 5.02 TeV. In particular, the values in p–Pb and Pb–Pb collisions differ by about two standard deviations of the combined statistical and systematic uncertainties in the common pT interval covered by the measurements in the two collision systems. The + c /D0 ratio is also compared with model calculations including different implementations of charm quark hadronisation. The measured ratio is reproduced by models implementing a pure coalescence scenario, while adding a fragmentation contribution leads to an underestimation. The + c nuclear modification factor, RAA, is also presented. The measured values of the RAA of + c , D+ s and non-strange D mesons are compatible within the combined statistical and systematic uncertainties. They show, however, a hint of a hierarchy (RD0 AA < RD+ s AA < R+ c AA ), conceivable with a contribution from coalescence mechanisms to charm hadron formation in the medium.
In this letter, the production of deuterons and anti-deuterons in pp collisions at √s = 7 TeV is studied as a function of the charged-particle multiplicity density at mid-rapidity with the ALICE detector at the LHC. Production yields are measured at mid-rapidity in five multiplicity classes and as a function of the deuteron transverse momentum (pT). The measurements are discussed in the context of hadron–coalescence models. The coalescence parameter B2, extracted from the measured spectra of (anti-)deuterons and primary (anti-)protons, exhibits no significant pT-dependence for pT < 3 GeV/c, in agreement with the expectations of a simple coalescence picture. At fixed transverse momentum per nucleon, the B2 parameter is found to decrease smoothly from low multiplicity pp to Pb–Pb collisions, in qualitative agreement with more elaborate coalescence models. The measured mean transverse momentum of (anti-)deuterons in pp is not reproduced by the Blast-Wave model calculations that simultaneously describe pion, kaon and proton spectra, in contrast to central Pb–Pb collisions. The ratio between the pT-integrated yield of deuterons to protons, d/p, is found to increase with the chargedparticle multiplicity, as observed in inelastic pp collisions at different centre-of-mass energies. The d/p ratios are reported in a wide range, from the lowest to the highest multiplicity values measured in pp collisions at the LHC.
Background: Previously, we used inhibitors blocking BET bromodomain binding proteins (BRDs) in Ewing sarcoma (EwS) and observed that long term treatment resulted in the development of resistance. Here, we analyze the possible interaction of BRD4 with cyclin-dependent kinase (CDK) 9. Methods: Co-immunoprecipitation experiments (CoIP) to characterize BRD4 interaction and functional consequences of inhibiting transcriptional elongation were assessed using drugs targeting of BRD4 or CDK9, either alone or in combination. Results: CoIP revealed an interaction of BRD4 with EWS-FLI1 and CDK9 in EwS. Treatment of EwS cells with CDKI-73, a specific CDK9 inhibitor (CDK9i), induced a rapid downregulation of EWS-FLI1 expression and block of contact-dependent growth. CDKI-73 induced apoptosis in EwS, as depicted by cleavage of Caspase 7 (CASP7), PARP and increased CASP3 activity, similar to JQ1. Microarray analysis following CDKI-73 treatment uncovered a transcriptional program that was only partially comparable to BRD inhibition. Strikingly, combined treatment of EwS with BRD- and CDK9-inhibitors re-sensitized cells, and was overall more effective than individual drugs not only in vitro but also in a preclinical mouse model in vivo. Conclusion: Treatment with BRD inhibitors in combination with CDK9i offers a new treatment option that significantly blocks the pathognomonic EWS-ETS transcriptional program and malignant phenotype of EwS.
We present the first measurements of femtoscopic correlations between the K0 S and K± particles in pp collisions at √s = 7 TeV measured by the ALICE experiment. The observed femtoscopic correlations are consistent with final-state interactions proceeding solely via the a0(980) resonance. The extracted kaon source radius and correlation strength parameters for K0 SK− are found to be equal within the experimental uncertainties to those for K0 SK+. Results of the present study are compared with those from identical-kaon femtoscopic studies also performed with pp collisions at √s = 7 TeV by ALICE andwith a K0 SK± measurement in Pb–Pb collisions at √sNN = 2.76 TeV. Combined with the Pb–Pb results, our pp analysis is found to be compatible with th e interpretation of the a0(980) having a tetraquark structure instead of that of a diquark.