Refine
Year of publication
Language
- English (634)
Has Fulltext
- yes (634) (remove)
Is part of the Bibliography
- no (634)
Keywords
- BESIII (19)
- e +-e − Experiments (15)
- Branching fraction (11)
- LHC (9)
- Particle and Resonance Production (8)
- Quarkonium (7)
- Charm Physics (6)
- Spectroscopy (6)
- Hadronic decays (5)
- Heavy-ion collisions (5)
- ALICE experiment (4)
- Branching fractions (4)
- Charmonium (4)
- Exotics (4)
- Lepton colliders (4)
- ALICE (3)
- Charmed mesons (3)
- Diffraction (3)
- Elastic scattering (3)
- Electroweak interaction (3)
- Experimental nuclear physics (3)
- Experimental particle physics (3)
- Initial state radiation (3)
- Polarization (3)
- e+-e− Experiments (3)
- pp collisions (3)
- Absolute branching fraction (2)
- Beam Energy Scan (2)
- Beauty production (2)
- Bhabha (2)
- Charm physics (2)
- Chiral Magnetic Effect (2)
- Collectivity (2)
- Correlation (2)
- Cross section (2)
- Electroweak Interaction (2)
- Elliptic flow (2)
- Flavour Physics (2)
- Hadronic cross section (2)
- Jets (2)
- Leptonic, semileptonic & radiative decays (2)
- Muon anomaly (2)
- Particle decays (2)
- Pb–Pb collisions (2)
- Pion form factor (2)
- QCD (2)
- Quark-Gluon Plasma (2)
- RHIC (2)
- Radiative decay (2)
- STAR (2)
- Shear viscosity (2)
- Single electrons (2)
- decays (2)
- 900 GeV (1)
- ALICE detector (1)
- Angular distribution (1)
- Annihilation (1)
- Anti-nuclei (1)
- B-slope (1)
- BESIII detector (1)
- BRD4 (1)
- Beam energy scan (1)
- Born cross section (1)
- Born cross section measurement (1)
- Branching fraction measurement (1)
- CDK9 (1)
- COVID-19 (1)
- CP violation (1)
- Canonical suppression (1)
- Charged-particle multiplicity (1)
- Charm quark spatial diffusion coefficient (1)
- Charm vector (1)
- Charmed baryon (1)
- Charmonia (1)
- Charmonium (-like) (1)
- Chiral magnetic effect (1)
- Coalescence (1)
- Cold nuclear matter effects (1)
- Comparison with QCD (1)
- Covariance matrix (1)
- Critical point (1)
- Cross section measurements (1)
- D meson (1)
- D0 and D+ mesons (1)
- Dalitz decay (1)
- Dark photon (1)
- Dark sector (1)
- Data sharing (1)
- Deuteron production (1)
- Di-hadron correlations (1)
- D⁰ meson (1)
- Effective form factor (1)
- Electromagnetic amplitude (1)
- Electromagnetic form factor (1)
- Electromagnetic form factors (1)
- Electron-pion identification (1)
- Ewing sarcoma (1)
- FOS: Physical sciences (1)
- Femtoscopy (1)
- Fibre/foam sandwich radiator (1)
- Flavor changing neutral currents (1)
- Flavor symmetries (1)
- Flow (1)
- Form factors (1)
- Forward physics (1)
- Genetics (1)
- Groomed jet radius (1)
- HBT (1)
- Hadron production (1)
- Hadron-Hadron Scattering (1)
- Hadron-Hadron Scattering Heavy (1)
- Hadron-Hadron scattering (experiments) (1)
- Hadron-hadron interactions (1)
- Hadronization (1)
- Hadrons (1)
- Heavy Ion Experiment (1)
- Heavy Ion Experiments (1)
- Heavy Ions (1)
- Heavy Quark Production (1)
- Heavy flavor production (1)
- Heavy flavour production (1)
- Heavy ion collisions (1)
- Heavy-Ion Collision (1)
- Heavy-flavor decay electron (1)
- Heavy-flavour decay muons (1)
- Heavy-flavour production (1)
- Heavy-ion (1)
- Helicity amplitude analysis (1)
- High Energy Physics - Experiment (hep-ex) (1)
- Higher moments (1)
- Hyperons (1)
- Inclusive branching fraction (1)
- Inclusive spectra (1)
- Intensity interferometry (1)
- Interference fragmentation function (1)
- Invisible decays (1)
- Ionisation energy loss (1)
- J/ψ suppression (1)
- Jet substructure (1)
- Jets and Jet Substructure (1)
- K0S (1)
- Mid-rapidity (1)
- Molecular biology (1)
- Multi-strange baryons (1)
- Multi-wire proportional drift chamber (1)
- Multiple parton interactions (1)
- NMR spectroscopy (1)
- Net-charge correlations (1)
- Net-charge fluctuations (1)
- Neural network (1)
- Neutrinos (1)
- Nonflow (1)
- Nuclear modification factor (1)
- PYTHIA (1)
- Particle and resonance production (1)
- Particle phenomena (1)
- Particle production (1)
- Pb–Pb (1)
- Phase (1)
- Properties of Hadrons (1)
- Proton (1)
- Proton-proton collisions (1)
- Proton–proton (1)
- Proton–proton collisions (1)
- Quantum chromodynamics (1)
- Quark Production (1)
- Quark–gluon plasma (1)
- R value (1)
- Rare decays (1)
- Relativistic heavy-ion collisions (1)
- Resonances (1)
- SARS-CoV-2 (1)
- Semi-leptonic decays (1)
- Single muons (1)
- SoftDrop (1)
- Spin alignment (1)
- Splitting function (1)
- Strangeness enhancement (1)
- Strong amplitude (1)
- TR (1)
- Techniques Electromagnetic calorimeters (1)
- Thermal model (1)
- Threshold effect (1)
- Tracking (1)
- Transition radiation detector (1)
- Transverse momentum (1)
- Transversity (1)
- Trigger (1)
- Triple quarkonia (1)
- Vector Boson Production (1)
- W-exchange (1)
- Xenon-based gas mixture (1)
- Y (4260) (1)
- Y states (1)
- accessory proteins (1)
- alleles (1)
- autism spectrum disorder (1)
- autistic disorder (1)
- branching fractions (1)
- cell-free protein synthesis (1)
- center-of-mass energy (1)
- charmed baryon (1)
- charmonium-like states (1)
- combination therapy (1)
- copy number polymorphism (1)
- dE/dx (1)
- decay (1)
- dimuon (1)
- diphoton (1)
- e+e − annihilation (1)
- e+e⁻ − Experiments (1)
- e+e− Experiments (1)
- e+e− annihilation (1)
- electron-positron collision (1)
- genes (1)
- genetics (1)
- genome (1)
- genotype (1)
- genotype determination (1)
- global change (1)
- habitat destruction (1)
- hadron spectroscopy (1)
- hadronic events (1)
- heavy-ion collisions (1)
- helicity amplitude analysis (1)
- inclusive J/ψ decays (1)
- intrinsically disordered region (1)
- land use (1)
- luminosity (1)
- nonstructural proteins (1)
- number of J/ψ events (1)
- p+p collisions (1)
- phenotype (1)
- single nucleotide polymorphism (1)
- spectra (1)
- structural proteins (1)
- tetraquark (1)
- trigger efficiency (1)
- tumor growth (1)
- Λ+c baryon (1)
- Λc⁺ (1)
- Σ hyperon (1)
- Υ suppression (1)
- ψ(3686) (1)
- √sN N = 2.76 TeV (1)
The procedure for the energy calibration of the high granularity electromagnetic calorimeter PHOS of the ALICE experiment is presented. The methods used to perform the relative gain calibration, to evaluate the geometrical alignment and the corresponding correction of the absolute energy scale, to obtain the nonlinearity correction coefficients and finally, to calculate the time-dependent calibration corrections, are discussed and illustrated by the PHOS performance in proton-proton (pp) collisions at s√=13 TeV. After applying all corrections, the achieved mass resolution of π0 and η mesons for pT>1.7 GeV/c is σπ0m=4.56±0.03 MeV/c2 and σηm=15.3±1.0 MeV/c2.
The procedure for the energy calibration of the high granularity electromagnetic calorimeter PHOS of the ALICE experiment is presented. The methods used to perform the relative gain calibration, to evaluate the geometrical alignment and the corresponding correction of the absolute energy scale, to obtain the nonlinearity correction coefficients and finally, to calculate the time-dependent calibration corrections, are discussed and illustrated by the PHOS performance in proton-proton (pp) collisions at s√ = 13 TeV. After applying all corrections, the achieved mass resolutions for π0 and η mesons for pT>1.7 GeV/c are σπ0m=4.56±0.03 MeV/c2 and σηm=15.3±1.0 MeV/c2, respectively.
The production of Z0 bosons at large rapidities in Pb–Pb collisions at √sNN = 5.02 TeV is reported. Z0 candidates are reconstructed in the dimuon decay channel (Z0 → μ+ μ−), based on muons selected with pseudo-rapidity −4.0 < η < −2.5 and pT > 20 GeV/c. The invariant yield and the nuclear modification factor, RAA, are presented as a function of rapidity and collision centrality. The value of RAA for the 0–20% central Pb–Pb collisions is 0.67 ± 0.11 (stat.) ± 0.03 (syst.) ± 0.06 (corr. syst.), exhibiting a deviation of 2.6σ from unity. The results are well-described by calculations that include nuclear modifications of the parton distribution functions, while the predictions using vacuum PDFs deviate from data by 2.3σ in the 0–90% centrality class and by 3σ in the 0–20% central collisions.
The Transition Radiation Detector (TRD) was designed and built to enhance the capabilities of the ALICE detector at the Large Hadron Collider (LHC). While aimed at providing electron identification and triggering, the TRD also contributes significantly to the track reconstruction and calibration in the central barrel of ALICE. In this paper the design, construction, operation, and performance of this detector are discussed. A pion rejection factor of up to 410 is achieved at a momentum of 1 GeV/c in p-Pb collisions and the resolution at high transverse momentum improves by about 40% when including the TRD information in track reconstruction. The triggering capability is demonstrated both for jet, light nuclei, and electron selection.
The Transition Radiation Detector (TRD) was designed and built to enhance the capabilities of the ALICE detector at the Large Hadron Collider (LHC). While aimed at providing electron identification and triggering, the TRD also contributes significantly to the track reconstruction and calibration in the central barrel of ALICE. In this paper the design, construction, operation, and performance of this detector are discussed. A pion rejection factor of up to 410 is achieved at a momentum of 1 GeV/c in p-Pb collisions and the resolution at high transverse momentum improves by about 40% when including the TRD information in track reconstruction. The triggering capability is demonstrated both for jet, light nuclei, and electron selection.
The Transition Radiation Detector (TRD) was designed and built to enhance the capabilities of the ALICE detector at the Large Hadron Collider (LHC). While aimed at providing electron identification and triggering, the TRD also contributes significantly to the track reconstruction and calibration in the central barrel of ALICE. In this paper the design, construction, operation, and performance of this detector are discussed. A pion rejection factor of up to 410 is achieved at a momentum of 1 GeV/c in p–Pb collisions and the resolution at high transverse momentum improves by about 40% when including the TRD information in track reconstruction. The triggering capability is demonstrated both for jet, light nuclei, and electron selection.
Autism spectrum disorder (ASD) is a highly heritable disorder of complex and heterogeneous aetiology. It is primarily characterized by altered cognitive ability including impaired language and communication skills and fundamental deficits in social reciprocity. Despite some notable successes in neuropsychiatric genetics, overall, the high heritability of ASD (~90%) remains poorly explained by common genetic risk variants. However, recent studies suggest that rare genomic variation, in particular copy number variation, may account for a significant proportion of the genetic basis of ASD. We present a large scale analysis to identify candidate genes which may contain low-frequency recessive variation contributing to ASD while taking into account the potential contribution of population differences to the genetic heterogeneity of ASD. Our strategy, homozygous haplotype (HH) mapping, aims to detect homozygous segments of identical haplotype structure that are shared at a higher frequency amongst ASD patients compared to parental controls. The analysis was performed on 1,402 Autism Genome Project trios genotyped for 1 million single nucleotide polymorphisms (SNPs). We identified 25 known and 1,218 novel ASD candidate genes in the discovery analysis including CADM2, ABHD14A, CHRFAM7A, GRIK2, GRM3, EPHA3, FGF10, KCND2, PDZK1, IMMP2L and FOXP2. Furthermore, 10 of the previously reported ASD genes and 300 of the novel candidates identified in the discovery analysis were replicated in an independent sample of 1,182 trios. Our results demonstrate that regions of HH are significantly enriched for previously reported ASD candidate genes and the observed association is independent of gene size (odds ratio 2.10). Our findings highlight the applicability of HH mapping in complex disorders such as ASD and offer an alternative approach to the analysis of genome-wide association data.
Background: Alzheimer's disease is a common debilitating dementia with known heritability, for which 20 late onset susceptibility loci have been identified, but more remain to be discovered. This study sought to identify new susceptibility genes, using an alternative gene-wide analytical approach which tests for patterns of association within genes, in the powerful genome-wide association dataset of the International Genomics of Alzheimer's Project Consortium, comprising over 7 m genotypes from 25,580 Alzheimer's cases and 48,466 controls.
Principal findings: In addition to earlier reported genes, we detected genome-wide significant loci on chromosomes 8 (TP53INP1, p = 1.4×10−6) and 14 (IGHV1-67 p = 7.9×10−8) which indexed novel susceptibility loci.
Significance: The additional genes identified in this study, have an array of functions previously implicated in Alzheimer's disease, including aspects of energy metabolism, protein degradation and the immune system and add further weight to these pathways as potential therapeutic targets in Alzheimer's disease.
The highly infectious disease COVID-19 caused by the Betacoronavirus SARS-CoV-2 poses a severe threat to humanity and demands the redirection of scientific efforts and criteria to organized research projects. The international COVID19-NMR consortium seeks to provide such new approaches by gathering scientific expertise worldwide. In particular, making available viral proteins and RNAs will pave the way to understanding the SARS-CoV-2 molecular components in detail. The research in COVID19-NMR and the resources provided through the consortium are fully disclosed to accelerate access and exploitation. NMR investigations of the viral molecular components are designated to provide the essential basis for further work, including macromolecular interaction studies and high-throughput drug screening. Here, we present the extensive catalog of a holistic SARS-CoV-2 protein preparation approach based on the consortium’s collective efforts. We provide protocols for the large-scale production of more than 80% of all SARS-CoV-2 proteins or essential parts of them. Several of the proteins were produced in more than one laboratory, demonstrating the high interoperability between NMR groups worldwide. For the majority of proteins, we can produce isotope-labeled samples of HSQC-grade. Together with several NMR chemical shift assignments made publicly available on covid19-nmr.com, we here provide highly valuable resources for the production of SARS-CoV-2 proteins in isotope-labeled form.
Rare copy-number variation (CNV) is an important source of risk for autism spectrum disorders (ASDs). We analyzed 2,446 ASD-affected families and confirmed an excess of genic deletions and duplications in affected versus control groups (1.41-fold, p = 1.0 × 10(-5)) and an increase in affected subjects carrying exonic pathogenic CNVs overlapping known loci associated with dominant or X-linked ASD and intellectual disability (odds ratio = 12.62, p = 2.7 × 10(-15), ∼3% of ASD subjects). Pathogenic CNVs, often showing variable expressivity, included rare de novo and inherited events at 36 loci, implicating ASD-associated genes (CHD2, HDAC4, and GDI1) previously linked to other neurodevelopmental disorders, as well as other genes such as SETD5, MIR137, and HDAC9. Consistent with hypothesized gender-specific modulators, females with ASD were more likely to have highly penetrant CNVs (p = 0.017) and were also overrepresented among subjects with fragile X syndrome protein targets (p = 0.02). Genes affected by de novo CNVs and/or loss-of-function single-nucleotide variants converged on networks related to neuronal signaling and development, synapse function, and chromatin regulation.