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Systematic studies of charge-dependent two- and three-particle correlations in Pb-Pb collisions at sNN−−−√= 2.76 and 5.02 TeV used to probe the Chiral Magnetic Effect (CME) are presented. These measurements are performed for charged particles in the pseudorapidity (η) and transverse momentum (pT) ranges |η|<0.8 and 0.2<pT<5 GeV/c. A significant charge-dependent signal that becomes more pronounced for peripheral collisions is reported for the CME-sensitive correlators γ1,1=⟨cos(φα+φβ−2Ψ2)⟩ and γ1,−3=⟨cos(φα−3φβ+2Ψ2)⟩. The results are used to estimate the contribution of background effects, associated with local charge conservation coupled to anisotropic flow modulations, to measurements of the CME. A blast-wave parametrisation that incorporates local charge conservation tuned to reproduce the centrality dependent background effects is not able to fully describe the measured γ1,1. Finally, the charge and centrality dependence of mixed-harmonics three-particle correlations, of the form γ1,2=⟨cos(φα+2φβ−3Ψ3)⟩, which are insensitive to the CME signal, verify again that background contributions dominate the measurement of γ1,1.
Systematic studies of charge-dependent two- and three-particle correlations in Pb-Pb collisions at sNN−−−√= 2.76 and 5.02 TeV used to probe the Chiral Magnetic Effect (CME) are presented. These measurements are performed for charged particles in the pseudorapidity (η) and transverse momentum (pT) ranges |η|<0.8 and 0.2<pT<5 GeV/c. A significant charge-dependent signal that becomes more pronounced for peripheral collisions is reported for the CME-sensitive correlators γ1,1=⟨cos(φα+φβ−2Ψ2)⟩ and γ1,−3=⟨cos(φα−3φβ+2Ψ2)⟩. The results are used to estimate the contribution of background effects, associated with local charge conservation coupled to anisotropic flow modulations, to measurements of the CME. A blast-wave parametrisation that incorporates local charge conservation tuned to reproduce the centrality dependent background effects is not able to fully describe the measured γ1,1. Finally, the charge and centrality dependence of mixed-harmonics three-particle correlations, of the form γ1,2=⟨cos(φα+2φβ−3Ψ3)⟩, which are insensitive to the CME signal, verify again that background contributions dominate the measurement of γ1,1.
Coherent photoproduction of ρ0 vector mesons in ultra-peripheral Pb–Pb collisions at √sNN = 5.02 TeV
(2020)
Cross sections for the coherent photoproduction of ρ0 vector mesons in ultra-peripheral Pb-Pb collisions at sNN−−−√=5.02 TeV are reported. The measurements, which rely on the π+π− decay channel, are presented in three regions of rapidity covering the range |y|<0.8. For each rapidity interval, cross sections are shown for different nuclear-breakup classes defined according to the presence of neutrons measured in the zero-degree calorimeters. The results are compared with predictions based on different models of nuclear shadowing. Finally, the observation of a coherently produced resonance-like structure with a mass around 1.7 GeV/c2 and a width of about 140 MeV/c2 is reported and compared with similar observations from other experiments.
Coherent photoproduction of ρ0 vector mesons in ultra-peripheral Pb–Pb collisions at √sNN = 5.02 TeV
(2020)
Cross sections for the coherent photoproduction of ρ0 vector mesons in ultra-peripheral Pb-Pb collisions at sNN−−−√=5.02 TeV are reported. The measurements, which rely on the π+π− decay channel, are presented in three regions of rapidity covering the range |y|<0.8. For each rapidity interval, cross sections are shown for different nuclear-breakup classes defined according to the presence of neutrons measured in the zero-degree calorimeters. The results are compared with predictions based on different models of nuclear shadowing. Finally, the observation of a coherently produced resonance-like structure with a mass around 1.7 GeV/c2 and a width of about 140 MeV/c2 is reported and compared with similar observations from other experiments.
This paper presents the measurements of π±, K±, p and p¯ transverse momentum (pT) spectra as a function of charged-particle multiplicity density in proton-proton (pp) collisions at s√ = 13 TeV with the ALICE detector at the LHC. Such study allows us to isolate the center-of-mass energy dependence of light-flavour particle production. The measurements reported here cover a pT range from 0.1 GeV/c to 20 GeV/c and are done in the rapidity interval |y|<0.5. The pT-differential particle ratios exhibit an evolution with multiplicity, similar to that observed in pp collisions at s√ = 7 TeV, which is qualitatively described by some of the hydrodynamical and pQCD-inspired models discussed in this paper. Furthermore, the pT-integrated hadron-to-pion yield ratios measured in pp collisions at two different center-of-mass energies are consistent when compared at similar multiplicities. This also extends to strange and multistrange hadrons, suggesting that, at LHC energies, particle hadrochemistry scales with particle multiplicity the same way under different collision energies and colliding systems.
This paper presents the measurements of π±, K±, p and p¯ transverse momentum (pT) spectra as a function of charged-particle multiplicity density in proton-proton (pp) collisions at s√ = 13 TeV with the ALICE detector at the LHC. Such study allows us to isolate the center-of-mass energy dependence of light-flavour particle production. The measurements reported here cover a pT range from 0.1 GeV/c to 20 GeV/c and are done in the rapidity interval |y|<0.5. The pT-differential particle ratios exhibit an evolution with multiplicity, similar to that observed in pp collisions at s√ = 7 TeV, which is qualitatively described by some of the hydrodynamical and pQCD-inspired models discussed in this paper. Furthermore, the pT-integrated hadron-to-pion yield ratios measured in pp collisions at two different center-of-mass energies are consistent when compared at similar multiplicities. This also extends to strange and multi-strange hadrons, suggesting that, at LHC energies, particle hadrochemistry scales with particle multiplicity the same way under different collision energies and colliding systems.
Inclusive ψ(2S) production is measured in p-Pb collisions at the centre-of-mass energy per nucleon-nucleon pair sNN−−−√=8.16 TeV, using the ALICE detector at the CERN LHC. The production of ψ(2S) is studied at forward (2.03<ycms<3.53) and backward (−4.46<ycms<−2.96) centre-of-mass rapidity and for transverse momentum pT < 12 GeV/c via the decay to muon pairs. In this paper, we report the integrated as well as the ycms- and pT-differential inclusive production cross sections. Nuclear effects on ψ(2S) production are studied via the determination of the nuclear modification factor that shows a strong suppression at both forward and backward centre-of-mass rapidities. Comparisons with corresponding results for inclusive J/ψ show a similar suppression for the two states at forward rapidity (p-going direction), but a stronger suppression for ψ(2S) at backward rapidity (Pb-going direction). As a function of pT, no clear dependence of the nuclear modification factor is found. The relative size of nuclear effects on ψ(2S) production compared to J/ψ is also studied via the double ratio of production cross sections [σψ(2S)/σJ/ψ]pPb/[σψ(2S)/σJ/ψ]pp between p-Pb and pp collisions. The results are compared with theoretical models that include various effects related to the initial and final state of the collision system and also with previous measurements at sNN−−−√ = 5.02 TeV.
This article reports measurements of the pT-differential inclusive jet cross-section in pp collisions at s√ = 5.02 TeV and the pT-differential inclusive jet yield in Pb-Pb 0-10% central collisions at sNN−−−√ = 5.02 TeV. Jets were reconstructed at mid-rapidity with the ALICE tracking detectors and electromagnetic calorimeter using the anti-kT algorithm. For pp collisions, we report jet cross-sections for jet resolution parameters R=0.1−0.6 over the range 20<pT,jet<140 GeV/c, as well as the jet cross-section ratios of different R, and comparisons to two next-to-leading-order (NLO)-based theoretical predictions. For Pb-Pb collisions, we report the R=0.2 and R=0.4 jet spectra for 40<pT,jet<140 GeV/c and 60<pT,jet<140 GeV/c, respectively. The scaled ratio of jet yields observed in Pb-Pb to pp collisions, RAA, is constructed, and exhibits strong jet quenching and a clear pT-dependence for R=0.2. No significant R-dependence of the jet RAA is observed within the uncertainties of the measurement. These results are compared to several theoretical predictions.
This article reports measurements of the pT-differential inclusive jet cross-section in pp collisions at s√ = 5.02 TeV and the pT-differential inclusive jet yield in Pb-Pb 0-10% central collisions at sNN−−−√ = 5.02 TeV. Jets were reconstructed at mid-rapidity with the ALICE tracking detectors and electromagnetic calorimeter using the anti-kT algorithm. For pp collisions, we report jet cross-sections for jet resolution parameters R=0.1−0.6 over the range 20<pT,jet<140 GeV/c, as well as the jet cross-section ratios of different R, and comparisons to two next-to-leading-order (NLO)-based theoretical predictions. For Pb-Pb collisions, we report the R=0.2 and R=0.4 jet spectra for 40<pT,jet<140 GeV/c and 60<pT,jet<140 GeV/c, respectively. The scaled ratio of jet yields observed in Pb-Pb to pp collisions, RAA, is constructed, and exhibits strong jet quenching and a clear pT-dependence for R=0.2. No significant R-dependence of the jet RAA is observed within the uncertainties of the measurement. These results are compared to several theoretical predictions.
This article reports measurements of the pT-differential inclusive jet cross-section in pp collisions at s√ = 5.02 TeV and the pT-differential inclusive jet yield in Pb-Pb 0-10% central collisions at sNN−−−√ = 5.02 TeV. Jets were reconstructed at mid-rapidity with the ALICE tracking detectors and electromagnetic calorimeter using the anti-kT algorithm. For pp collisions, we report jet cross-sections for jet resolution parameters R=0.1−0.6 over the range 20<pT,jet<140 GeV/c, as well as the jet cross-section ratios of different R, and comparisons to two next-to-leading-order (NLO)-based theoretical predictions. For Pb-Pb collisions, we report the R=0.2 and R=0.4 jet spectra for 40<pT,jet<140 GeV/c and 60<pT,jet<140 GeV/c, respectively. The scaled ratio of jet yields observed in Pb-Pb to pp collisions, RAA, is constructed, and exhibits strong jet quenching and a clear pT-dependence for R=0.2. No significant R-dependence of the jet RAA is observed within the uncertainties of the measurement. These results are compared to several theoretical predictions.
Background: Alzheimer's disease is a common debilitating dementia with known heritability, for which 20 late onset susceptibility loci have been identified, but more remain to be discovered. This study sought to identify new susceptibility genes, using an alternative gene-wide analytical approach which tests for patterns of association within genes, in the powerful genome-wide association dataset of the International Genomics of Alzheimer's Project Consortium, comprising over 7 m genotypes from 25,580 Alzheimer's cases and 48,466 controls.
Principal findings: In addition to earlier reported genes, we detected genome-wide significant loci on chromosomes 8 (TP53INP1, p = 1.4×10−6) and 14 (IGHV1-67 p = 7.9×10−8) which indexed novel susceptibility loci.
Significance: The additional genes identified in this study, have an array of functions previously implicated in Alzheimer's disease, including aspects of energy metabolism, protein degradation and the immune system and add further weight to these pathways as potential therapeutic targets in Alzheimer's disease.
Coherent photoproduction of ρ⁰ vector mesons in ultra-peripheral Pb-Pb collisions at √sNN = 5.02 TeV
(2020)
Cross sections for the coherent photoproduction of ρ0 vector mesons in ultra-peripheral Pb-Pb collisions at sNN−−−√ = 5.02 TeV are reported. The measurements, which rely on the π+π− decay channel, are presented in three regions of rapidity covering the range |y| < 0.8. For each rapidity interval, cross sections are shown for different nuclear-breakup classes defined according to the presence of neutrons measured in the zero-degree calorimeters. The results are compared with predictions based on different models of nuclear shadowing. Finally, the observation of a coherently produced resonance-like structure with a mass around 1.7 GeV/c2 and a width of about 140 MeV/c2 is reported and compared with similar observations from other experiments.