Refine
Year of publication
Document Type
- Preprint (864)
- Article (559)
- Working Paper (1)
Language
- English (1424)
Has Fulltext
- yes (1424)
Is part of the Bibliography
- no (1424)
Keywords
- Heavy Ion Experiments (21)
- BESIII (19)
- e +-e − Experiments (16)
- Branching fraction (12)
- Hadron-Hadron scattering (experiments) (12)
- Hadron-Hadron Scattering (11)
- Particle and Resonance Production (9)
- Quarkonium (8)
- Charm Physics (6)
- Heavy-ion collision (6)
- Spectroscopy (6)
- Hadronic decays (5)
- QCD (5)
- Branching fractions (4)
- Charm physics (4)
- Charmonium (4)
- Collective Flow (4)
- Electroweak interaction (4)
- Exotics (4)
- Heavy-ion collisions (4)
- Lepton colliders (4)
- Quark-Gluon Plasma (4)
- Charmed mesons (3)
- Diffraction (3)
- Experimental nuclear physics (3)
- Experimental particle physics (3)
- Heavy Quark Production (3)
- Initial state radiation (3)
- Jets (3)
- Jets and Jet Substructure (3)
- Particle and resonance production (3)
- e+-e− Experiments (3)
- Absolute branching fraction (2)
- Beam Energy Scan (2)
- Bhabha (2)
- Chiral Magnetic Effect (2)
- Collectivity (2)
- Correlation (2)
- Cross section (2)
- Elastic scattering (2)
- Electroweak Interaction (2)
- Flavour Physics (2)
- Hadronic cross section (2)
- Heavy Ions (2)
- LHC (2)
- Lepton-Nucleon Scattering (experiments) (2)
- Leptonic, semileptonic & radiative decays (2)
- Muon anomaly (2)
- Particle Correlations and Fluctuations (2)
- Particle correlations and fluctuations (2)
- Particle decays (2)
- Pion form factor (2)
- Radiative decay (2)
- Shear viscosity (2)
- decays (2)
- 900 GeV (1)
- ALICE (1)
- ALICE detector (1)
- Alleles (1)
- Angular distribution (1)
- Annihilation (1)
- Anti-nuclei (1)
- Aortic valve (1)
- Apoptosis (1)
- Atmospheric science (1)
- B-slope (1)
- BESIII detector (1)
- Beam energy scan (1)
- Boosted Jets (1)
- Born cross section (1)
- Born cross section measurement (1)
- Branching fraction measurement (1)
- CP violation (1)
- Canonical suppression (1)
- Cell proliferation (1)
- Centrality Class (1)
- Centrality Selection (1)
- Charged-particle multiplicity (1)
- Charm quark spatial diffusion coefficient (1)
- Charm vector (1)
- Charmed baryon (1)
- Charmonium (-like) (1)
- Chiral magnetic effect (1)
- Climate change (1)
- Coalescence (1)
- Cold nuclear matter effects (1)
- Collective Flow, (1)
- Covariance matrix (1)
- Critical point (1)
- Cross section measurements (1)
- D meson (1)
- D0 and D+ mesons (1)
- Dalitz decay (1)
- Danxia landform (1)
- Dark photon (1)
- Dark sector (1)
- Deuteron production (1)
- Di-hadron correlations (1)
- D⁰ meson (1)
- Effective form factor (1)
- Electromagnetic amplitude (1)
- Electromagnetic form factor (1)
- Electromagnetic form factors (1)
- Electron-pion identification (1)
- Elliptic flow (1)
- Endothelial cells (1)
- FOS: Physical sciences (1)
- Fibre/foam sandwich radiator (1)
- Flavor changing neutral currents (1)
- Flavor symmetries (1)
- Form factors (1)
- Forward physics (1)
- Groomed jet radius (1)
- Hadron-Hadron Scattering Heavy (1)
- Hadron-hadron interactions (1)
- Hadrons (1)
- Hard Scattering (1)
- Heart (1)
- Heavy Ion Experiment (1)
- Heavy ion storage ring (1)
- Heavy ions (1)
- Heavy-Ion Collision (1)
- Heavy-flavor decay electron (1)
- Helicity amplitude analysis (1)
- High Energy Physics - Experiment (hep-ex) (1)
- Higher moments (1)
- Homeostasis (1)
- Hyperons (1)
- Immunostaining (1)
- Inclusive branching fraction (1)
- Interference fragmentation function (1)
- Invariant Mass Distribution (1)
- Invasive plants and animals (1)
- Invisible decays (1)
- Ionisation energy loss (1)
- J/ψ suppression (1)
- Jet Physics (1)
- Jet Substructure (1)
- Jet substructure (1)
- K0S (1)
- Material budget (1)
- Minimum Bias (1)
- Monte Carlo (1)
- Multi-Parton Interactions (1)
- Multi-wire proportional drift chamber (1)
- Multiple parton interactions (1)
- Neural network (1)
- Neutrinos (1)
- Orbital electron capture (1)
- PYTHIA (1)
- Particle phenomena (1)
- Particle production (1)
- Pb–Pb collisions (1)
- Phase (1)
- Polarization (1)
- Production Cross Section (1)
- Properties of Hadrons (1)
- Proton (1)
- Proton-proton collisions (1)
- Proton–proton collisions (1)
- Quantum chromodynamics (1)
- Quark Deconfinement (1)
- Quark Gluon Plasma (1)
- Quark Production (1)
- Quark gluon plasma (1)
- Quark–gluon plasma (1)
- R value (1)
- RHIC (1)
- Rapidity Range (1)
- Rare decays (1)
- Relativistic heavy ion physics (1)
- Relativistic heavy-ion collisions (1)
- Resolution Parameter (1)
- Resonances (1)
- STAR (1)
- Semi-leptonic decays (1)
- Single particle decay spectroscopy (1)
- SoftDrop (1)
- Splitting function (1)
- Strangeness enhancement (1)
- Strong amplitude (1)
- Systematic Uncertainty (1)
- TR (1)
- Techniques Electromagnetic calorimeters (1)
- Thermal model (1)
- Threshold effect (1)
- Time Projection Chamber (1)
- Tracking (1)
- Transition radiation detector (1)
- Transverse momentum (1)
- Transversity (1)
- Trigger (1)
- Triple quarkonia (1)
- Two body weak decay (1)
- Vector Boson Production (1)
- W-exchange (1)
- Xenon-based gas mixture (1)
- Y (4260) (1)
- Y states (1)
- branching fractions (1)
- cave (1)
- center-of-mass energy (1)
- charmed baryon (1)
- charmonium-like states (1)
- cryptic species (1)
- dE/dx (1)
- decay (1)
- detector (1)
- dimuon (1)
- diphoton (1)
- distribution (1)
- e+e − annihilation (1)
- e+e⁻ − Experiments (1)
- e+e− Experiments (1)
- e+e− annihilation (1)
- electron-positron collision (1)
- experimental results (1)
- hadron spectroscopy (1)
- hadronic events (1)
- heavy ion experiments (1)
- heavy-ion collisions (1)
- helicity amplitude analysis (1)
- inclusive J/ψ decays (1)
- luminosity (1)
- number of J/ψ events (1)
- origin (1)
- p+p collisions (1)
- pathway (1)
- quark gluon plasma (1)
- rate of introduction (1)
- southern China (1)
- tetraquark (1)
- trigger efficiency (1)
- Λ+c baryon (1)
- Λc⁺ (1)
- Σ hyperon (1)
- Υ suppression (1)
- ψ(3686) (1)
Institute
- Physik (1306)
- Frankfurt Institute for Advanced Studies (FIAS) (963)
- Informatik (830)
- Biowissenschaften (5)
- Buchmann Institut für Molekulare Lebenswissenschaften (BMLS) (5)
- Informatik und Mathematik (3)
- Center for Financial Studies (CFS) (1)
- ELEMENTS (1)
- Geowissenschaften (1)
- Geowissenschaften / Geographie (1)
The epitranscriptome embodies many new and largely unexplored functions of RNA. A major roadblock in the epitranscriptomics field is the lack of transcriptome-wide methods to detect more than a single RNA modification type at a time, identify RNA modifications in individual molecules, and estimate modification stoichiometry accurately. We address these issues with CHEUI (CH3 (methylation) Estimation Using Ionic current), a new method that concurrently detects N6-methyladenosine (m6A) and 5-methylcytidine (m5C) in individual RNA molecules from the same sample, as well as differential methylation between any two conditions. CHEUI processes observed and expected nanopore direct RNA sequencing signals with convolutional neural networks to achieve high single-molecule accuracy and outperforms other methods in detecting m6A and m5C sites and quantifying their stoichiometry. CHEUI’s unique capability to identify two modification types in the same sample reveals a non-random co-occurrence of m6A and m5C in mRNA transcripts in cell lines and tissues. CHEUI unlocks an unprecedented potential to study RNA modification configurations and discover new epitranscriptome functions.
The epitranscriptome embodies many new and largely unexplored functions of RNA. A major roadblock in the epitranscriptomics field is the lack of transcriptome-wide methods to detect more than a single RNA modification type at a time, identify RNA modifications in individual molecules, and estimate modification stoichiometry accurately. We address these issues with CHEUI (CH3 (methylation) Estimation Using Ionic current), a new method that concurrently detects N6-methyladenosine (m6A) and 5-methylcytidine (m5C) in individual RNA molecules from the same sample, as well as differential methylation between any two conditions. CHEUI processes observed and expected nanopore direct RNA sequencing signals with convolutional neural networks to achieve high single-molecule accuracy and outperforms other methods in detecting m6A and m5C sites and quantifying their stoichiometry. CHEUI’s unique capability to identify two modification types in the same sample reveals a non-random co-occurrence of m6A and m5C in mRNA transcripts in cell lines and tissues. CHEUI unlocks an unprecedented potential to study RNA modification configurations and discover new epitranscriptome functions.
The epitranscriptome embodies many new and largely unexplored functions of RNA. A major roadblock in the epitranscriptomics field is the lack of transcriptome-wide methods to detect more than a single RNA modification type at a time, identify RNA modifications in individual molecules, and estimate modification stoichiometry accurately. We address these issues with CHEUI (CH3 (methylation) Estimation Using Ionic current), a new method that concurrently detects N6-methyladenosine (m6A) and 5-methylcytidine (m5C) in individual RNA molecules from the same sample, as well as differential methylation between any two conditions. CHEUI processes observed and expected nanopore direct RNA sequencing signals with convolutional neural networks to achieve high single-molecule accuracy and outperforms other methods in detecting m6A and m5C sites and quantifying their stoichiometry. CHEUI’s unique capability to identify two modification types in the same sample reveals a non-random co-occurrence of m6A and m5C in mRNA transcripts in cell lines and tissues. CHEUI unlocks an unprecedented potential to study RNA modification configurations and discover new epitranscriptome functions.
The epitranscriptome embodies many new and largely unexplored functions of RNA. A major roadblock in the epitranscriptomics field is the lack of transcriptome-wide methods to detect more than a single RNA modification type at a time, identify RNA modifications in individual molecules, and estimate modification stoichiometry accurately. We address these issues with CHEUI (CH3 (methylation) Estimation Using Ionic current), a new method that concurrently detects N6-methyladenosine (m6A) and 5-methylcytidine (m5C) in individual RNA molecules from the same sample, as well as differential methylation between any two conditions. CHEUI processes observed and expected nanopore direct RNA sequencing signals with convolutional neural networks to achieve high single-molecule accuracy and outperforms other methods in detecting m6A and m5C sites and quantifying their stoichiometry. CHEUI’s unique capability to identify two modification types in the same sample reveals a non-random co-occurrence of m6A and m5C in mRNA transcripts in cell lines and tissues. CHEUI unlocks an unprecedented potential to study RNA modification configurations and discover new epitranscriptome functions.