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This paper examines the development of periphrastic constructions involving auxiliary "have" and "be" with a past participle in the history of English, on the basis of parsed electronic corpora. It is argued that the two constructions represented distinct syntactic and semantic structures: while the one with have developed into a true perfect in the course of Middle English, the one with be remained a stative resultative throughout its history. In this way, it is explained why the be construction was rarely or never used in a number of contexts, including past counterfactuals, iteratives, duratives, certain kinds of infinitives and various other utterance types that cannot be characterized as perfects of result. When the construction with have became a true perfect, it was used in such contexts, regardless of the identity of the main verb, leading to the appearance of have with verbs like come which had previously only taken be. Crucially, however, have was not spreading at the expense of be, as the be perfect had never been used in such contexts, but rather at the expense of the old simple past. At least until the end of the Early Modern English period, the shift in the relative frequency of have and be perfects is to be explained in terms of the expansion of the former into new contexts, while the latter remained stable. A formal analysis is proposed, taking as its starting point a comparison with German which shows that the older English be perfect indeed behaves more like the German stative passive than its haben and sein perfects.
Meeting Abstract : 27. Deutscher Krebskongress. Berlin, 22.-26.03.2006.
Docetaxel, Adriamycin, Cyclophosphamide (TAC) is considered today as one treatment option for patients with node-positive primary breast cancer. However, treatment is associated with anaemia grade 1-4 (2-4) in up to 95% (36%) of patients. We prospectively investigated the use of a primary prophylaxis with Darbepoetin alfa once every 3 weeks in 35 patients receiving six to eight cycles of TAC as neoadjuvant treatment for breast cancer. Darbepoetin treatment started on day 1 of a TAC cycle if haemoglobin (Hb) was ≤ 14.0 g/dl. Dosage was adapted to 9 µg/kg if Hb was ≤ 13.0 g/dl on day 21 of the previous cycle, to 4.5 µg/kg if Hb was between 13.0 and 14.0 g/dl and was discontinued if Hb increased to ≥ 14 g/dl. The primary aim was to prevent Hb levels ≤ 12 g/dl before surgery. During 112 (50.2%) and 93 (41.7%) of 223 cycles, 4.5 µg/kg and 9 µg/kg Darbepoetin were given, respectively. Dosage was decreased from 9 to 4.5 µg/kg in 21 (60%) patients and 28 (12.4%) cycles. Treatment was discontinued due to Hb > 14.0 g/dl in 12 (34.3%) patients and 13 (5.4%) cycles. Hb level on day 21 of the last cycle was ≤ 12.0 g/dl in 4 (11.4%) patients. Eighteen (51.4%) patients during 36 (16.1%) cycles showed Hb levels ≤ 12 g/dl throughout treatment. No NCI-CTC grade 2 to 4 anaemia was observed. Symptoms of fatigue (FACT-AN) decreased slightly throughout treatment. Anaemia during TAC chemotherapy can be avoided by a single injection of Darbepoetin alfa every 3 weeks.
The mission of the Harvard Judaica Collection is to comprehensively document Jewish history and civilization in all places and periods. To accomplish its mission, the Judaica Collection collects materials in all languages and in all formats—books, pamphlets, periodicals, newspapers, sound recordings, and videos, posters, broadsides, and photographs. A particular focus is the Library’s Documenting Israel program, which covers all aspects of Israeli life and culture in great depth; Harvard has the largest collection of Israeli publications and Israel-related materials outside the State of Israel. The Harvard Judaica Collection also attempts to have comprehensive coverage of the publications of Jewish communities throughout the globe, including a significant collection of publications from countries across Europe. Collecting these materials requires cooperation with a wide array of institutions and individuals around the world.
The LOCKSS (Lots of Copies Keep Stuff Safe) Alliance is an international community of about 100 libraries and partners like OCLC. For almost a decade the LOCKSS open source model has been tested for its robustness against attack and for its ability to migrate formats. LOCKSS »boxes« at 150 institutions in more than 20 countries comprise a peer-to-peer system that automatically cross-checks content to ensure the accuracy and completeness of all member archives. Eighty publishers, including large publishers like Oxford University Press, are now participating in LOCKSS or actively preparing to add their journals to the program.
U. S. library resources on South Asia that were built around the limited needs of a handful of Sanskritics before World War II have made a long journey during the past half century. Since the inception of the Library of Congress Cooperative South Asia Acquisition Program (formerly called "PL-480" program), in 1962, libraries have built significant collections with financial support from governmental agencies and philanthropic foundations, to support teaching and research in all areas of social sciences and humanities. These collections have been supplemented by efforts to build retrospective collections and to microfilm rare materials in British and South Asian libraries and archives. Today, in cooperation with South Asian libraries, several projects are underway to preserve and digitize rapidly deteriorating materials so that these riches can be shared with the global scholarly community through electronic means.
To stimulate further discussion, I would like to briefly tackle the following questions: * How can one become informed about what is going on in German Studies in the US? * What kinds of American guides to German resources are available? * What kinds of German Studies resources are being produced in the US? * What do we know about how scholars are using (or not) these guides and resources?
The enhancing importance of digital documents has effected activities on how to deal with them. One line came from the more general field of "scientific publishing", which was handled in detail by DINI (Deutsche Initiative für Netzwerkinformation). But for this initiative long- time archiving was only one field of many and was not their primary focus. DINI first of all concentrated on the elaboration of effective and standardized methods and tools for publishing and related services on the basis of open access policy via the use of institutional repositories. The second line of projects came from the more general view of maintaining cultural heritage also in a digital world. Especially under the patronage of the Ministry of Education and Research important projects were being financed. Strategic solutions including archives, libraries, and museums are discussed and elaborated within NESTOR, where more technical solutions based on the term of practicability are developed within KOPAL. KOPAL brought together the industry (IBM) with a public- funded technical center (GWDG) and two libraries (DNB and SUB Göttingen). Within this project a general software implementation, which took into consideration all necessary international standards, could be finished last month and has been now for about two weeks. Based on early results within NESTOR it seemed important too, to strengthen all activities by giving them a legal basis. Therefore when the law changed concerning the German National Library from June 22nd this year (DNBG), the library was authorized with all the necessary instruments to collect digital documents in "non-physical" form as well. With this law at the moment Germany is in the rare position of being one of the few countries where the collection of network publications is part of the whole legal deposit strategy.
Background and Purpose of this Meeting With an opening reception sponsored by Thomson Scientific on the evening of Thursday, October 5, the University Library of Frankfurt and the German-North American Resources Partnership (GNARP) and will be hosting an important two-day conference this Autumn in Frankfurt, Germany: »The World According to GNARP: Prospects for Transatlantic Library Partnership in the Digital Age« Sessions at this meeting will explore the wealth of library resources - archival, print, and digital - available to students and researchers (in Germany and the United States) in five selected subject areas: North American Studies, German Studies, Judaica, Africana, and South Asia/India, highlighting both existing avenues (and obstacles) for transatlantic resource sharing along with future prospects. In addition, several other important topics will be highlighted through individual presentations and panel discussions: the future of German as a language of the sciences; existing and planned electronic journal archives in Germany and the U.S.; print and digital repositories; and a special panel on »comparative cataloging cultures« on both sides of the Atlantic. The »World According to GNARP« conference will be taking place simultaneously with the Frankfurt Book Fair, the largest book-related event in the world, attracting annually 285,000 visitors (2005), thus giving participants who arrive early the chance to combine attendance at both the Book Fair and Conference. A cultural event and dinner in Frankfurt are planned for Friday 6th October.
Bewahren und Erschließen : die deutschsprachige jüdische Presse und das Projekt Compact Memory
(2006)
Jüdische Zeitschriften stellen für die Erforschung des jüdischen Kultur-erbes eine unverzichtbare Quelle dar. Vollständige Ausgaben der Periodika sind auf Grund des schlechten Erhaltungszustandes und der Zerstörungen durch Krieg und Nationalsozialismus nur noch in wenigen Bibliotheken vorhanden, so dass ihre Nutzung schwierig ist. Compact Memory bietet als Datenbank weltweit freien Online-Zugang zu den Zeit-schriften in digitalisierter Form an und stellt ein wichtiges Hilfsmittel für die Erforschung der modernen mitteleuropäisch-jüdischen Geschichte dar. 118 verschiedene Titel mit insgesamt circa 700.000 Seiten, welche die unterschiedlichsten Strömungen des Judentums repräsentieren, sind als Grafiken bzw. als Volltext zugänglich, außerdem kann in einer Suchmaske gezielt recherchiert werden. Mit der Aufnahme in das UNESCO Archives Portal hat Compact Memory internationale Anerkennung erlangt.