Refine
Year of publication
- 1967 (1)
Document Type
- Article (1)
Language
- German (1) (remove)
Has Fulltext
- yes (1)
Is part of the Bibliography
- no (1) (remove)
Institute
- Biochemie und Chemie (1) (remove)
The trifluoroacetylation of thymidine at room temperature was performed using trifluoroacetic acid phenylester in pyridine. A selective protection of the 5′-position was not possible: Even low molar quantities of the trifluoroacetylating agent gave rise to bis-trifluoroacetylation. The bis-trifluoroacetyl derivatives of thymidine and 5-bromo-deoxyuridine were purified by vacuum sublimation. The completely trifluoroacetylated deoxyribosides of uracil, 5-iodouracil and adenine underwent decomposition during sublimation.