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Complexome profiling is an emerging ‘omics’ approach that systematically interrogates the composition of protein complexes (the complexome) of a sample, by combining biochemical separation of native protein complexes with mass-spectrometry based quantitation proteomics. The resulting fractionation profiles hold comprehensive information on the abundance and composition of the complexome, and have a high potential for reuse by experimental and computational researchers. However, the lack of a central resource that provides access to these data, reported with adequate descriptions and an analysis tool, has limited their reuse. Therefore, we established the ComplexomE profiling DAta Resource (CEDAR, www3.cmbi.umcn.nl/cedar/), an openly accessible database for depositing and exploring mass spectrometry data from complexome profiling studies. Compatibility and reusability of the data is ensured by a standardized data and reporting format containing the “minimum information required for a complexome profiling experiment” (MIACE). The data can be accessed through a user-friendly web interface, as well as programmatically using the REST API portal. Additionally, all complexome profiles available on CEDAR can be inspected directly on the website with the profile viewer tool that allows the detection of correlated profiles and inference of potential complexes. In conclusion, CEDAR is a unique, growing and invaluable resource for the study of protein complex composition and dynamics across biological systems.
Mapeamento de estudos da linguística contrastiva Português/Alemão : dados bibliográficos no Brasil
(2021)
Este trabalho tem como propósito relatar o desenvolvimento, a metodologia e os resultados de um Projeto de Iniciação Científica que propõe a construção de uma base de dados da bibliografia da linguística contrastiva Português/Alemão. De natureza documentalbibliográfica, a coletânea bibliográfica foi realizada em bases de dados brasileiras de publicações em português, e as referências compiladas no software Zotero. As buscas foram realizadas entre agosto e dezembro de 2019 e se utilizou as palavras-chave (Língua Alemã; Língua Portuguesa; Alemão; Português; Linguística; Linguística Contrastiva), assim como as grandes áreas da Linguística (Morfologia; Fonética; Fonologia; Semântica; Pragmática e Sintaxe). Foram identificadas ao todo 48 pesquisas, publicadas entre os anos de 1972 e 2019, classificadas entre Literatura Branca e Literatura Cinzenta. Os dados apontam uma prevalência de artigos publicados no periódico Pandaemonium Germanicum, da Universidade de São Paulo (USP), especialmente na década de 1990, assim como um grande número de pesquisas na área de semântica.
The aim of this study is to examine economic terminology using the terminology database developed in the e-learning platform Moodle. The focus is on English terms from the daily press, their current position in German and Czech, and also on different equivalence types in their translation. Using digital reference works (Duden online, Management Mania, the English-German-Czech specialist dictionary Magnus Expert), the definitions and translations were searched for and interpreted, and the selected terms subsequently categorized into groups. It is shown that the terminology database in Moodle is not a well-studied source for lexicographical, translational and general linguistic research, although it offers a wide range of different Internet-based methodological approaches.