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Studies investigating the prevalence, cause, and consequence of multiple sclerosis (MS) fatigue typically use single measures that implicitly assume symptom-stability over time, neglecting information about if, when, and why severity fluctuates. We aimed to examine the extent of moment-to-moment and day-to-day variability in fatigue in relapsing-remitting MS and healthy individuals, and identify daily life determinants of fluctuations. Over 4 weekdays, 76 participants (38 relapsing-remitting MS; 38 controls) recruited from multiple sites provided real-time self-reports six times daily (n = 1661 observations analyzed) measuring fatigue severity, stressors, mood, and physical exertion, and daily self-reports of sleep quality. Fatigue fluctuations were evident in both groups. Fatigue was highest in relapsing-remitting MS, typically peaking in late-afternoon. In controls, fatigue started lower and increased steadily until bedtime. Real-time stressors and negative mood were associated with increased fatigue, and positive mood with decreased fatigue in both groups. Increased fatigue was related to physical exertion in relapsing-remitting MS, and poorer sleep quality in controls. In relapsing-remitting MS, fatigue fluctuates substantially over time. Many daily life determinants of fluctuations are similar in relapsing-remitting MS and healthy individuals (stressors, mood) but physical exertion seems more relevant in relapsing-remitting MS and sleep quality most relevant in healthy individuals.
Exercise interventions in mental disorders have evidenced a mood-enhancing effect. However, the association between physical activity and affect in everyday life has not been investigated in adult individuals with ADHD, despite being important features of this disorder. As physical activity and affect are dynamic processes in nature, assessing those in everyday life with e-diaries and wearables, has become the gold standard. Thus, we used an mHealth approach to prospectively assess physical activity and affect processes in individuals with ADHD and controls aged 14–45 years. Participants wore accelerometers across a four-day period and reported their affect via e-diaries twelve times daily. We used multilevel models to identify the within-subject effects of physical activity on positive and negative affect. We split our sample into three groups: 1. individuals with ADHD who were predominantly inattentive (n = 48), 2. individuals with ADHD having a combined presentation (i.e., being inattentive and hyperactive; n = 95), and 3. controls (n = 42). Our analyses revealed a significant cross-level interaction (F(2, 135.072)=5.733, p = 0.004) of physical activity and group on positive affect. In details, all groups showed a positive association between physical activity and positive affect. Individuals with a combined presentation significantly showed the steepest slope of physical activity on positive affect (slope_inattentive=0.005, p<0.001; slope_combined=0.009, p<0.001; slope_controls=0.004, p = 0.008). Our analyses on negative affect revealed a negative association only in the individuals with a combined presentation (slope=-0.003; p = 0.001). Whether this specifically pronounced association in individuals being more hyperactive might be a mechanism reinforcing hyperactivity needs to be empirically clarified in future studies.
Volker Woltersdorff's essay 'Sexual Ghosts and the Whole of History: Queer Historiography, Post-Slavery Subjectivities, and Sadomasochism in Isaac Julien's "The Attendant"' discusses the controversial concept of wholeness in historiography with regard to the fascination with past horrors and the desire to do justice to their victims who retain a ghostly presence. The essay retraces how this commitment produces a dilemma, as it can result either in the aspiration to historical wholeness as full memoralization or alternatively in the radical rejection of wholeness as an impossible healing. Employing Elizabeth Freeman's notion of 'erotohistoriography', Woltersdorff introduces affect into the work of historiography in order to find an escape from the dilemmatic impasse between history's wholeness as pacified reconciliation and as ongoing catastrophe along the lines of Walter Benjamin. Sadomasochism is presented as a practice that may correspond most adequately to the paradoxical affect caused by traumatic history that continues to haunt the present. Indeed, re-enactments of historical oppression and violence occur frequently within the BDSM community. However, what distinguishes them from 'living history' re-enactments is their potential to modify affective attachments to history by altering the historical script. The essay elaborates this potential through Isaac Julien's 1993 short film "The Attendant", which, in a kind of queer re-enactment, overwrites the memory of colonial chattel slavery by a sadomasochistic encounter of a black guardian and a white visitor in a museum dedicated to the history of slavery. The film raises the ethical and political question of how to relate affectively to the legacy and ongoing presence of racism. Against this backdrop, the author argues that, through the BDSM scenario and its changes to the historical script, Julien's film represents and promotes a paradoxical way to perform both the memorialization and the forgetting of past horrors and pleasures. Here, historical wholeness acquires a conflicting double meaning of both achieving completeness and restoring integrity. Woltersdorff concludes by interpreting "The Attendant" as urging a utopian perspective, produced by the tension between the impossibility of history's wholeness and the necessary, reparative desire for it. The article concludes by highlighting the paradox that Julien's film shows wholeness 'to be impossible and yet necessary' and 'expresses a necessary desire made impossible'. While the essay explicitly engages with the figure of haunting, one could perhaps speak here also of plasticity insofar as the contradictory conjunction of remembering and forgetting seems to rely on a malleability of affects and on producing an affective economy that sustains the fantasmatic remembrance of a painful past through paradoxical pleasure but breaks with any pleasure derived from real inequality, injustice, or suffering imparted non-consensually.
Repetition
(2019)
This article explores the creative value of the notion of 'repetition' in Michel Foucault's texts from the 1960s and early 1970s. Re-enacting Gilles Deleuze's philosophy, Foucault implicitly refers to the Freudian repetition mechanisms in order to distort and reverse them. Foucault's repetition is de-psychologized, affectively de-individualizing, and temporally erratic, using the power of a senseless repetition to create new possibilities for the future.
Recherche II : anamnesis
(2019)
The temporal loop of Proust's "Recherche" complicates the unidirectional understanding of anamnesis in psychoanalysis, which, in turn, allows for a renewed reading of the temporality of the "Recherche", highlighting the intrinsic link between artistic 'research' and unconscious affect - at the same time origin, motif, and destination.
This essay approaches the problem of untying the mother tongue using Philippe Lacoue-Labarthe's critique of onto-typology, along with the concept of the 'outre-mère' (the 'beyond-mother'), a limit-figure he and Jean-Luc Nancy devised in their critical assessments of psychoanalysis and its relationship to politics and the problem of mimesis. The essay argues that it will not be possible to deconstruct the figure of the mother tongue, or to untie ourselves from it, as long as we leave unquestioned both the theoretical dependence on figuration and our affective tie ('Gefühlsbindung') to theory.