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Ḥoveret taḳtsirim : kenes ha-Ḥevrah ha-Geologit 2018 : Yiśraʿel-Ḳafrisin 25.03.2018 - 29.03.2018
(2018)
This lecture is about the history of the "Naier idisher teater" in Riga, the construction process of the building since 1913, the people and organisations that were involved, the theatre opening, playing schedules, companies, cooperation and actors as well as about the intercultural, economic and social environments and activities around the theatre until it was closed forcibly by the German troupes in 1941.
Von der Gruppenarbeit zum Community Building - der "Digital Creative Space" der SUB Göttingen
(2018)
Die Förderung der digitalen Kompetenzen von Studierenden und die Entwicklung adaptiver, interaktiver und multimedialer (digitaler), diversitätsorientierter Lernumgebungen sind Schwerpunkte der Digitalen Hochschulbildung. Dies hat auch erheblichen Einfluss auf die konzeptionelle Planung und Gestaltung von physischen Lernraumangeboten wissenschaftlicher Bibliotheken. Ein deutliches Desiderat ist dabei die Bereitstellung niedrigschwelliger, kollaborativ nutzbarer Lernumgebungen, in denen Studierende (und auch Lehrende) gemeinsam digitale Kenntnisse erwerben, explorativ erproben und stärken können, um den Anforderungen sowohl im Studium als auch im späteren Berufsleben gerecht werden zu können. Gemeinsam mit dem Service für Digitales Lernen und Lehren und der Abteilung IT der Universität Göttingen hat die Benutzungsabteilung der SUB Göttingen ein Raumkonzept für ein "Digital Creative Space" erarbeitet, das in gemeinsamen Workshops mit Studierenden und Lehrenden des Göttinger Campus weiterentwickelt wurde. Sein Start in der hochfrequentierten Zentralbibliothek ist für 2018 geplant. Das Ergebnis dieses Prozesses ist eine Bündelung interdisziplinärer Labs verschiedenster technischer Ausstattung und interdisziplinärer Gruppenarbeit - das "Digital Creative Space". Ziel ist, den Nutzenden das eigenständige Entwickeln digitaler Kompetenzen zu ermöglichen und kreative Prozesse zu unterstützen - und dabei "communities of practice" zu initiieren oder zu befördern. Das Konzept, seine Entwicklungs- und weiteren Umsetzungsschritte einschließlich der Darstellung des partizipativen Prozesses sind Inhalt dieses Vortrags.
We report on the status of ongoing investigations aiming at locating the deconfinement critical point with standard Wilson fermions and Nf = 2 flavors towards the continuum limit (standard Columbia plot); locating the tricritical masses at imaginary chemical potential with unimproved staggered fermions at Nf = 2 (extended Columbia plot); identifying the order of the chiral phase transition at μ = 0 for Nf = 2 via extrapolation from non integer Nf (alternative Columbia plot).
We study the properties of the survival probability of an unstable quantum state described by a Lee Hamiltonian. This theoretical approach resembles closely Quantum Field Theory (QFT): one can introduce in a rather simple framework the concept of propagator and Feynman rules, Within this context, we re-derive (in a detailed and didactical way) the well-known result according to which the amplitude of the survival probability is the Fourier transform of the energy distribution (or spectral function) of the unstable state (in turn, the energy distribution is proportional to the imaginary part of the propagator of the unstable state). Typically, the survival probability amplitude is the starting point of many studies of non-exponential decays. This work represents a further step toward the evaluation of the survival probability amplitude in genuine relativistic QFT. However, although many similarities exist, QFT presents some differences w.r.t. the Lee Hamiltonian which should be studied in the future.
Introduction: Ferroptosis has recently been identified as a form of programmed cell death caused by an accumulation of lipid reactive oxygen species (ROS). However, little is yet known about the role in hepatocellular carcinoma (HCC) and its signalling mechanism as well the modulation of ROS.
Material and methods: Human HCC cell lines were treated with different concentrations of ROS modulators (Auranofin, Erastin, BSO). Cell death was determined by analysis of PI-stained nuclei using flow cytometry. ROS production and lipid peroxidation were analysed at early time points before cell death starts. For mechanistic studies we performed Western Blot and a Proteome array. Different inhibitors of cell death target proteins, ROS-scavengers as well as lipoxygenase inhibitors were used. To investigate the functional relevance of NAPDH oxidases (NOX) 1 and 4 for ROS modulation and ferroptosis we genetically silenced its genes using three distinct siRNAs and we used the NOX1/4-inhibitor GKT137831.
Results and discussions: Compared to the single treatment, Auranofin/BSO-cotreatment as well as Erastin/BSO-cotreatment acted in concert to trigger cell death and to reduce cell viability of HCC cells in a dose- and time-dependent manner. Furthermore, both cotreatments induce ROS production, lipid peroxidation and ferroptotic cell death, which could be inhibited by the use of Ferrostatin-1 (inhibitor of lipid peroxidation) and Liproxstatin-1 (specific inhibitor of ferroptosis). The broad-range caspase inhibitor zVAD.fmk failed to rescue cells from Auranofin/BSO- or Erastin/BSO-cotreatment induced cell death. No activation of caspases-3 could be seen in the proteome profiler apoptosis assay. Importantly, the selective lipoxygenase (LOX) inhibitor Baicalain and the pan-LOX inhibitor NDGA protect HCC cells from Auranofin/BSO- and Erastin/BSO-cotreatment stimulated lipid peroxidation, ROS generation and cell death, indication that the induction of ferroptosis may bypass apoptosis resistance of HCC cells. Mechanistic studies showed that Auranofin/BSO-cotreatment decreased TrxR-activity, led to Nrf2 accumulation and promoted the activation of HO-1. In contrast, NOX 1 and 4 were involved in Erastin/BSO-mediated cell death and the use of the NOX1/4-inhibitor GKT137831 rescued HCC cells from the Erastin/BSO-induced cell death.
Conclusion: By providing new insights into the molecular regulation of ROS and ferroptosis, our study contributes to the development of novel treatment strategies to reactivate programmed cell death in HCC cells.
We study tetraquark resonances with lattice QCD potentials computed for two static quarks and two dynamical quarks, the Born-Oppenheimer approximation and the emergent wave method of scattering theory. As a proof of concept we focus on systems with isospin I = 0, but consider different relative angular momenta l of the heavy b quarks. We compute the phase shifts and search for S and T matrix poles in the second Riemann sheet. We predict a new tetraquark resonance for l = 1, decaying into two B mesons, with quantum numbers I(JP) = 0(1−), mass MeV and decay width MeV.
n this contribution we lay down a lattice setup that allows for the nonperturbative study of a field theoretical model where a SU(2) fermion doublet, subjected to non-Abelian gauge interactions, is also coupled to a complex scalar field doublet via a Yukawa and an “irrelevant” Wilson-like term. Using naive fermions in quenched approximation and based on the renormalizedWard identities induced by purely fermionic chiral transformations, lattice observables are discussed that enable: a) in theWigner phase, the determinations of the critical Yukawa coupling value where the purely fermionic chiral transformation become a symmetry up to lattice artifacts; b) in the Nambu-Goldstone phase of the resulting critical theory, a stringent test of the actual generation of a fermion mass term of non-perturbative origin. A soft twisted fermion mass term is introduced to circumvent the problem of exceptional configurations, and observables are then calculated in the limit of vanishing twisted mass.
This paper traces the military role of Tibnīn and its rulers in the Latin East against the Muslims until 1187/ 583. Tibnīn played a key role in overcoming the Muslims in Tyre and controlled it in 1124. It also played a vital role in the conflict between Damascus and the Kingdom of Jerusalem. Tibnīn participated in defending Antioch, Banyas, Hebron and Transjordan several times. Furthermore, its soldiers and Knights joined the army of the Kingdom of Jerusalem to capture Ascalon in 1153, and joined the campaigns of Amaury I, King of Jerusalem, against Egypt from 1164 to1169. The military situation of Tibnīn under the rule of the royal house until its fall to the Muslims in 1187/ 583 will be studied as well
Im Zeitraum vom 7. bis zum 9. Dezember 2017 fand an der Universität Breslau (Wrocław) in Kooperation mit der Ruhr-Universität Bochum die Winterschool "Europa: Poetik und Politik" statt. Die gut zwanzig Teilnehmerinnen und Teilnehmer – darunter Professor*innen, wissenschaftliche Mitarbeiter*innen und Studierende beider Universitäten – diskutierten die neuere Geschichte von Europa-Diskursen von der Romantik bis in die Gegenwart. Ausgangspunkt der Tagung war die gegenwärtige Krise der Europäischen Union, die – so zeigte sich im Verlauf der Tagung – als Fortführung der leitmotivischen 'Schwellensituationen' zu verstehen ist, die als das Gemeinsame der diskutierten Texte und somit in gewisser Weise als konstitutiv für den Europa-Diskurs erkannt wurden.
The High-Acceptance DiElectron Spectrometer (HADES) operates in the 1 - 2A GeV energy regime in fixed target experiments to explore baryon-rich strongly interacting matter in heavy-ion collisions at moderate temperatures with rare and penetrating probes. We present results on the production of strange hadrons below their respective NN threshold energy in Au+Au collisions at 1.23A GeV ( = 2.4 GeV). Special emphasis is put on the enhanced feed-down contribution of ϕ mesons to the inclusive yield of K- and its implication on the measured spectral shape of K-. Furthermore, we investigate global properties of the system, confronting the measured hadron yields and transverse mass spectra with a Statistical Hadronization Model (SHM) and a blastwave parameterization, respectively. These supplement the world data of the chemical and kinetic freeze-out temperatures.
The standard implementation of the HRG model has been shown to be unable to describe all the available data on QCD matter. Here we show the balance of repulsive and attractive hadronic interactions on QCD thermodynamics through observables both calculated by lattice simulations and measured in experiment. Attractive interactions are mediated by resonance formation, which are here implemented through extra states predicted by the Quark Model, while repulsive interactions are modelled by means of Excluded Volume (EV) effects. Informations on flavour dependent effective sizes are extracted. It is found that EV effects are present in lattice QCD thermodynamics, and are essential for a comprehensive description of higher order fluctuations of conserved charges.
We investigate the properties of QCD at finite isospin chemical potential at zero and non-zero temperatures. This theory is not affected by the sign problem and can be simulated using Monte-Carlo techniques. With increasing isospin chemical potential and temperatures below the deconfinement transition the system changes into a phase where charged pions condense, accompanied by an accumulation of low modes of the Dirac operator. The simulations are enabled by the introduction of a pionic source into the action, acting as an infrared regulator for the theory, and physical results are obtained by removing the regulator via an extrapolation. We present an update of our study concerning the associated phase diagram using 2+1 flavours of staggered fermions with physical quark masses and the comparison to Taylor expansion. We also present first results for our determination of the equation of state at finite isospin chemical potential and give an example for a cosmological application. The results can also be used to gain information about QCD at small baryon chemical potentials using reweighting with respect to the pionic source parameter and the chemical potential and we present first steps in this direction.
We discuss the current developments by the European Twisted Mass Collaboration in extracting parton distribution functions from the quasi-PDF approach. We concentrate on the non-perturbative renormalization prescription recently developed by us, using the RI′ scheme. We show results for the renormalization functions of matrix elements needed for the computation of quasi-PDFs, including the conversion to the MS scheme, and for renormalized matrix elements. We discuss the systematic effects present in the Z-factors and the possible ways of addressing them in the future.
We investigate privacy concerns and the privacy behavior of users of the AR smartphone game Pokémon Go. Pokémon Go accesses several functionalities of the smartphone and, in turn, collects a plethora of data of its users. For assessing the privacy concerns, we conduct an online study in Germany with 683 users of the game. The results indicate that the majority of the active players are concerned about the privacy practices of companies. This result hints towards the existence of a cognitive dissonance, i.e. the privacy paradox. Since this result is common in the privacy literature, we complement the first study with a second one with 199 users, which aims to assess the behavior of users with regard to which measures they undertake for protecting their privacy. The results are highly mixed and dependent on the measure, i.e. relatively many participants use privacy-preserving measures when interacting with their smartphone. This implies that many users know about risks and might take actions to protect their privacy, but deliberately trade-off their information privacy for the utility generated by playing the game.
Targeting for rare observables, the CBM experiment will operate at high interaction rates of up to 10 MHz, which is unprecedented in heavy-ion experiments so far. It requires a novel free-streaming readout system and a new concept of data processing. The huge data rates of the CBM experiment will be reduced online to the recordable rate before saving the data to the mass storage. Full collision reconstruction and selection will be performed online in a dedicated processor farm. In order to make an efficient event selection online a clean sample of particles has to be provided by the reconstruction package called First Level Event Selection (FLES).
The FLES reconstruction and selection package consists of several modules: track finding, track fitting, event building, short-lived particles finding, and event selection. Since detector measurements contain also time information, the event building is done at all stages of the reconstruction process. The input data are distributed within the FLES farm in a form of time-slices. A time-slice is reconstructed in parallel between processor cores. After all tracks of the whole time-slice are found and fitted, they are collected into clusters of tracks originated from common primary vertices, which then are fitted, thus identifying the interaction points. Secondary tracks are associated with primary vertices according to their estimated production time. After that short-lived particles are found and the full event building process is finished. The last stage of the FLES package is a selection of events according to the requested trigger signatures. The event reconstruction procedure and the results of its application to simulated collisions in the CBM detector setup are presented and discussed in detail.
Einstein’s theory of general relativity is often regarded as the best theory of gravity that we know. Yet, this theory often manifests itself under conditions where no symmetry is present and nonlinear dynamics dominates. I will discuss how these conditions are systematically accompanied by the restoration of some degree of symmetry. Hence, despite gravity appearing often under conditions devoid of symmetry, asymptotic solutions tend to restore symmetry.
A 3d regional density-driven flow model of a heterogeneous aquifer system at the German North Sea Coast is set up within the joint project NAWAK (“Development of sustainable adaption strategies for the water supply and distribution infrastructure on condition of climatic and demographic change”). The development of the freshwater-saltwater interface is simulated for three climate and demographic scenarios.
Groundwater flow simulations are performed with the finite volume code d3f++ (distributed density driven flow) that has been developed with a view to the modelling of large, complex, strongly density-influenced aquifer systems over long time periods.