Refine
Year of publication
- 2009 (81)
- 2012 (58)
- 2018 (54)
- 2017 (51)
- 2011 (49)
- 2019 (48)
- 2016 (46)
- 2010 (45)
- 2020 (43)
- 2015 (34)
- 2013 (32)
- 2014 (32)
- 2008 (31)
- 1969 (23)
- 1967 (21)
- 2007 (19)
- 2021 (19)
- 1968 (18)
- 1976 (18)
- 1987 (18)
- 1988 (16)
- 1947 (15)
- 1970 (15)
- 2005 (15)
- 1975 (14)
- 2006 (14)
- 1971 (13)
- 1981 (13)
- 1977 (12)
- 2003 (12)
- 2004 (12)
- 1972 (11)
- 1966 (10)
- 1973 (10)
- 1963 (9)
- 1974 (9)
- 1978 (9)
- 1982 (9)
- 1994 (9)
- 1980 (8)
- 1989 (8)
- 1996 (8)
- 1960 (7)
- 1979 (7)
- 1985 (7)
- 2023 (7)
- 1964 (6)
- 1965 (6)
- 1983 (6)
- 2022 (6)
- 1984 (5)
- 1990 (5)
- 1992 (5)
- 1962 (4)
- 1991 (4)
- 1993 (4)
- 1995 (4)
- 2000 (4)
- 2002 (4)
- 1950 (3)
- 1951 (3)
- 1986 (3)
- 2024 (3)
- 1957 (2)
- 1959 (2)
- 1998 (2)
- 1999 (2)
- 1946 (1)
- 1948 (1)
- 1949 (1)
- 1952 (1)
- 1953 (1)
- 1956 (1)
- 1961 (1)
- 2001 (1)
Document Type
- Article (1110) (remove)
Has Fulltext
- yes (1110)
Is part of the Bibliography
- no (1110) (remove)
Keywords
- crystal structure (37)
- Crystal Structure (25)
- Synthesis (15)
- ESR Spectra (14)
- hydrogen bonding (11)
- IR Spectra (10)
- PE Spectra (8)
- NMR spectroscopy (7)
- Phase Diagrams (7)
- X-Ray (7)
- X-Ray Structure Analysis (7)
- structural biology (7)
- Addition Compounds (6)
- Electron Transfer (6)
- RNA (6)
- rna (6)
- Bioenergetics (5)
- Cyclic Voltammetry (5)
- ESR/ENDOR Spectra (5)
- MNDO Calculations (5)
- Membrane proteins (5)
- NMR (5)
- Optogenetics (5)
- Pyridine (5)
- Research article (5)
- Streptomyces hydrogenans (5)
- Super-resolution microscopy (5)
- X-ray crystallography (5)
- p63 (5)
- Biochemistry (4)
- Biophysical chemistry (4)
- Cell biology (4)
- Chemiluminescence (4)
- Cryoelectron microscopy (4)
- Kinases (4)
- Kinetics (4)
- MO Calculations (4)
- Phosphorylation (4)
- Silicon (4)
- Single Crystal Structure (4)
- Single Crystal Structures (4)
- Solution-state NMR (4)
- TATD (4)
- antibiotic resistance (4)
- atomic volume (4)
- biophysics (4)
- environmental tobacco smoke (4)
- inflammation (4)
- membrane proteins (4)
- mitochondria (4)
- nuclear magnetic resonance (NMR) (4)
- particulate matter (4)
- quality control (4)
- ABC Transporter (3)
- ATPases (3)
- Acridine Orange (3)
- Antigen Processing (3)
- Bacterial Chromosome (3)
- Contact Ion Pairs (3)
- Cyclic Compounds (3)
- Cyclovoltammetry (3)
- Enzyme Induction (3)
- Enzyme mechanisms (3)
- Lutidine (3)
- Membrane protein (3)
- PELDOR (3)
- Phase Diagram (3)
- Phosphorus (3)
- Photoelectron Spectra (3)
- Protein folding (3)
- Pyrazine (3)
- Quinones (3)
- Radical Complexes (3)
- Schiff bases (3)
- Substituent Effects (3)
- Tin (3)
- UV/VIS Spectra (3)
- X-ray (3)
- X-ray powder diffraction (3)
- allostery (3)
- apoptosis (3)
- base pairing (3)
- benzoxazines (3)
- co-crystalline adducts (3)
- cytotoxicity (3)
- high pressure (3)
- kinetics (3)
- membrane protein (3)
- membrane transport (3)
- packing density (3)
- phenolic resins (3)
- polymorphism (3)
- solid-state NMR (3)
- ubiquitin (3)
- 2-aminobenzimidazole (2)
- 20β-Hydroxysteroid Dehydrogenase (2)
- 5-lipoxygenase (2)
- AEC syndrome (2)
- Acetonitrile Adduct (2)
- Addition Compound (2)
- Affinity Labeling (2)
- Aluminium Chloride (2)
- Analysis (2)
- Atomic force microscopy (2)
- Biocatalysis (2)
- Biophysics and structural biology (2)
- CRISPR/Cas9 (2)
- Caenorhabditis elegans (2)
- Cell membranes (2)
- Complex Formation (2)
- Cycles (2)
- Cytochrome Oxidase (2)
- Dehydrogenases (2)
- Dimethyldichlorosilane (2)
- E. coli (2)
- EPR (2)
- ESR (2)
- Epoxides (2)
- Esters (2)
- Excess Volumes (2)
- Fluoro Compounds (2)
- G protein-coupled receptors (2)
- G-quadruplexes (2)
- Green chemistry (2)
- Heme (2)
- IAPs (2)
- Iodine (2)
- Ion Pair Formation (2)
- Ion transport (2)
- LILBID-MS (2)
- Lactate Dehydrogenase (2)
- Luciferase (2)
- Lutidines (2)
- Lysozyme (2)
- MET receptor (2)
- MHC (2)
- Membrane (2)
- Membrane biophysics (2)
- Membrane potential (2)
- Metabolic engineering (2)
- Metal Organic Derivatives (2)
- Methylchlorosilanes (2)
- Methylhalogenosilanes (2)
- Mitophagy (2)
- Molecular biology (2)
- Molecular conformation (2)
- Mycobacterium tuberculosis (2)
- NHC (2)
- NMR Spectra (2)
- Nanodisc (2)
- Nanoscale biophysics (2)
- Nitrogen (2)
- Organic electrochemistry (2)
- Organosilicon Compounds (2)
- Oxidation (2)
- Permeation and transport (2)
- Photodynamic Effect (2)
- Photoelectron (2)
- Photoreduction (2)
- Photosynthesis (2)
- Photosystem II (2)
- Pyridiniumbromide (2)
- Reaction Kinetics (2)
- Reduction (2)
- Reduction to Radical Anions (2)
- Semiempirical Calculations (2)
- Semiquinone (2)
- Silanide (2)
- Single-molecule biophysics (2)
- Singlet Oxygen (2)
- Solid-state NMR (2)
- Spectra (2)
- Spectroscopy (2)
- Stereochemistry (2)
- Supersilyl (2)
- Target validation (2)
- Tin Organic Compounds (2)
- Transport (2)
- Trifluoromethylation (2)
- Trimethylbromosilane (2)
- Virtual Screening (2)
- X-ray diffraction (2)
- XIAP (2)
- Yeast (2)
- additives (2)
- adenine (2)
- aminal structure (2)
- antibiotics (2)
- antigen presentation (2)
- autophagy (2)
- biochemistry (2)
- co-crystalline adduct (2)
- cryo-EM (2)
- deubiquitinase (DUB) (2)
- dynamics (2)
- electron cryo-microscopy (2)
- electrophysiology (2)
- guanidine analogs (2)
- halogen bonding (2)
- helix (snails) (2)
- hydrogen bond (2)
- hydrogen bonds (2)
- intrinsically disordered protein (2)
- leukotriene (2)
- macrophage (2)
- membrane protein complex (2)
- metabolism (2)
- metallic elements (2)
- microbial rhodopsin (2)
- molecular dynamics (2)
- multienzyme (2)
- nuclear magnetic resonance spectroscopy (2)
- oligonucleotides (2)
- peptide-loading complex (2)
- phage display (2)
- photopharmacology (2)
- pore-forming toxin (2)
- protein denaturation (2)
- proteins (2)
- pseudosymmetry (2)
- radiation-induced nanostructures (2)
- reactive oxygen species (2)
- secondary transport (2)
- short contacts (2)
- solvate (2)
- structure elucidation (2)
- subtomogram averaging (2)
- transcriptional regulation (2)
- tryptophan (2)
- yeast (2)
- (2-hydroxynaphthalen-1-yl)methyl (1)
- (Hydroxymethyl)diphenyl(piperidinoalkyl)silanes (1)
- (novel) brominated flame retardants ((N)BFR) (1)
- 1,1-dichloro-3,5-diphenyl-4-H-1,2,4,6-λ4-selenatriazine (1)
- 1,2,3 triazole (1)
- 1,2,3-Triazoles (1)
- 1,2,3-bis-triazoles (1)
- 1,2,3-triazole-acyclonucleosides (1)
- 1,2,4,5-Tetracyanobenzene (1)
- 1,2,4-thiadiazoles (1)
- 1,2-D ioxetanes (1)
- 1,2-Dimesitoylbenzene (1)
- 1,3-bis(2,6-di-methylphenyl)imidazol-2-ylidene (1)
- 1,3-diazinane (1)
- 1,3-dipolar cycloaddition (1)
- 1-(3-fluorophenyl)-3-(3,4,5-trimethoxybenzoyl)thiourea (1)
- 1-octanol (1)
- 1.10-Phenanthrolin-5,6-dione (1)
- 13C NMR Spectra (1)
- 14C-Labeled Terpenoids (1)
- 19F NM R Spectra (1)
- 1H NMR Spectra (1)
- 1H NMR; Conformational Properties (1)
- 1H and 13C NMR Spectroscopy (1)
- 2,5-Bis(trimethylsilyl)-p-quinone and -hydroquinone-monosodium Salt (1)
- 2-(2′-Pyridyl)indole Derivatives (1)
- 2-2-Dichloropropane (1)
- 20 β-Activity (1)
- 2H-Azirine (1)
- 3,17 β-Hydroxysteroid Dehydrogenase (1)
- 3,30′-ethane-1,2-diyl-bis-1,3,5-triazabicyclo[3.2.1]octane (1)
- 3,4-Benzopyrene (1)
- 3,4-Dimethylpyridine (1)
- 3-hydroxypropionaldehyde (1)
- 31P-NMR (1)
- 3D EM (1)
- 3D reconstruction and image processing (1)
- 3´-5´ phosphodiesterases (1)
- 4,4’-Disubstituted 2,2’-Bipyridines (1)
- 4-hydroxycyclophosphamide (1)
- 5-Hydroxyaloin A (1)
- 7,7,8,8-Tetracyano-p-quinodimethane (1)
- 7-Dehydrocholesterol (1)
- 9-aminoacridine (1)
- ABC proteins (1)
- ABC transporter (1)
- ABC transporters (1)
- ACPM (1)
- AM1 Calculations (1)
- AML – acute myeloid leukemia (1)
- APM (1)
- ATP synthase (1)
- ATP-citrate lyase (1)
- Ab-initio-Rechnungen (1)
- Acidic Amino Acids (1)
- Acinetobacter baumannii (1)
- Addition compounds (1)
- Adenocarcinoma (1)
- Adenylate Kinase (1)
- Adherens junctions (1)
- Adhesion (1)
- Affinity Chromatography (1)
- Aiolochroia crassa (1)
- Alcohols (1)
- Aldehydes (1)
- Alkali Metal Reduction (1)
- Alkaline and Alkaline Earth Metals (1)
- Alkylating Agents (1)
- Alkylating NAD-Analogs (1)
- Aloe (1)
- Aluminium Bromide (1)
- Aluminium bromide (1)
- Aluminium chloride (1)
- Aluminiumbromide (1)
- Alveolar macrophages (1)
- Aminoboranes (1)
- Ammonium Chloride (1)
- Amyloid proteins (1)
- Androst-4-en-3,17-dione (1)
- Anion Radicals (1)
- Anion and Zwitterion Transport (1)
- Anionic boranes (1)
- Anodic oxidation (1)
- Antibiotic Resistance (1)
- Antigens (1)
- Antimony Methyl Halides (1)
- Antiviral activity (1)
- Applied microbiology (1)
- Aprotic Conditions (1)
- Aprotic Solution (1)
- Aquaporin (1)
- Archaea (1)
- Archaebacterial Lipids (1)
- Archebacterial Lipids (1)
- Arduengo-type carbene (1)
- Aromatic Nitro Compounds (1)
- Arsenic (1)
- Asphodelaceae (1)
- Association (1)
- Asymmetric Catalysis (1)
- Atomic volume (1)
- Attenuated Total Reflection (1)
- Autophagy (1)
- Azidoacetonitrile Trimethylenetetrazole and Tetrazolo[1,5-a]pyridine (1)
- Azo Compounds (1)
- Azobenzene (1)
- Azodicarbonitrile (1)
- B-factor (1)
- B. subtilis (1)
- BET inhibitor (1)
- BET inhibitors (1)
- BN Addition Compounds (1)
- BPTI (1)
- Bacteria (1)
- Bacterial Protein Kinases (1)
- Bacterial Protein Phosphatases (1)
- Bacterial genomics (1)
- Bacterial structural biology (1)
- Bacteriophages (1)
- Base Catalysis (1)
- Beer (1)
- Benzoquinone Radical Anion (1)
- Biochemie (1)
- Biochemistry and chemical biology (1)
- Biofuel (1)
- Biopolymers in vivo (1)
- Biotin (1)
- Biradicals (1)
- Bis(N,N-diethyl-N′-benzoylselenoureato)lead(II) (1)
- Bis(η-cyclopentadienyl)titana(TiIV)cyclohexaselenane (1)
- Bis-azido-NAD+ Analog (1)
- Bisaboloids (1)
- Bisamidines (1)
- Bolhmann bands (1)
- Bond Order (1)
- Bradyrhizobium (1)
- Brownian dynamics simulation (1)
- Brønsted Acid (1)
- Brønsted base (1)
- C-H...Br hydrogen bond (1)
- C-H...O interactions (1)
- C-H...O interactions (1)
- C-H...[pi] interactions (1)
- C-H...[pi] interactions (1)
- C-mannosylation (1)
- C. elegans (1)
- CCR5 (1)
- CD4 binding site (1)
- CD44s (1)
- CD44v6 (1)
- CDC-42 (1)
- CEP-1 (1)
- CEP68 (1)
- CNN (1)
- CUE domain (1)
- CV9202 (1)
- CXCR4 (1)
- CaChR1 (1)
- Calycotome villosa (Poiret) Link Subsp. Intermedia (1)
- Cancer epidemiology (1)
- Caprylic acid (1)
- Carbene (1)
- Carbene Complexes (1)
- Carbene Transfer (1)
- Carbonates (1)
- Carbonyl Complexes (1)
- Carbonyl Compounds (1)
- Carboxylic acid reductase (1)
- Cas9 inhibitor (1)
- Cation Proton Antiporter (1)
- Cation/proton antiport (1)
- Cell Death Program (1)
- Cell Motility (1)
- Cell Surface Receptor (1)
- Cell signalling (1)
- Cell-free synthetic biology (1)
- Cellular Immune Response (1)
- Cesium (1)
- Cezanne (1)
- Channelrhodopsin (1)
- CheF (1)
- CheY (1)
- Chelate-Capped Hydrogen Bridges (1)
- Chelated Pentacoordinated Silicon (1)
- Chemometry (1)
- Chemotaxonomy (1)
- Chloromethylsilanes (1)
- Chlorophyll-a (1)
- Chromatin (1)
- Chromatin and Epigenetics (1)
- Chromium (1)
- Coenzyme Analogue (1)
- Coenzyme Binding (1)
- Coenzyme analogues (1)
- Cofactors (biochemistry) (1)
- Compound Database (1)
- Computation (1)
- Computational Biology (1)
- Computational biology and bioinformatics (1)
- Computational chemistry (1)
- Computational models (1)
- Conformational State (1)
- Conformational trapping (1)
- Conformers (1)
- Constrained posture (1)
- Contact Ion Pair [Ag⊕(PR3)2(R2H2C6O2·⊖)] (1)
- Contact Ion Pairs and Triples (1)
- Coordination Compounds (1)
- Coordinative Bonding (1)
- Copper(I) Chloride Adducts of Phosphoranimines (1)
- Cornea (1)
- Correlative electron and light microscopy (1)
- Coxsackievirus B3 (1)
- Cross-linking (1)
- Cryo-EM (1)
- Cryo-electron microscopy (1)
- Crystal Structure Analysis (1)
- Crystal Structure Dinuclear Ti-S and Ti-Se Complexes (1)
- Crystal Structure of [(η3-C4H7)6Pd6Se3] (1)
- Crystal Structure of [Co8Se8(PPh3)6]n (n = 0; 1+) (1)
- Crystal Structure of [Fe4Se4Br4]2--Cluster (1)
- Crystal Structures (1)
- Crystal and Molecular Structure (1)
- Cuela (1)
- Cyanine Distortion (1)
- Cyanine Distortion of C6-Rings (1)
- Cyanobacteria (1)
- Cyanogen Azide (1)
- Cyclic Organosulfides (1)
- Cyclic S-N-Compounds (1)
- Cyclic Sulfonyl Derivatives (1)
- Cyclopentadienyl Complexes (1)
- Cyclophosphamide (1)
- Cytochrome c Oxidase (1)
- Cytological techniques (1)
- Cytostatic Agents (1)
- C— H interactions (1)
- C— HCl contacts (1)
- C—H...π interactions (1)
- C—H⋯Br and C—H⋯O hydrogen bonds (1)
- C—H⋯Cl hydrogen bonds (1)
- C—H⋯O hydrogen bonds (1)
- C—H⋯π interactions (1)
- C−H···F (1)
- DEER (1)
- DFT (1)
- DIPSHIFT (1)
- DNA (1)
- DNA damage (1)
- DNA nanopores (1)
- DNA nanostructures (1)
- DNA-LNA mixmers (1)
- DNA-PAINT (1)
- DNA-ligand complexes (1)
- DNA/LNA mixmers (1)
- DSC-Curves (1)
- Data processing (1)
- Dehydrogenase (1)
- Dehydrogenase Cofactors (1)
- Delayed Light Emission (1)
- Dentist (1)
- Deoxyribonuclease Digestion (1)
- Depolarization (1)
- Dermatitis (1)
- Detergents (1)
- DgkA (1)
- Diabetes (1)
- Diabetes mellitus (1)
- Dialkylamino Substituted π Systems (1)
- Dialkylamino-substituted π-Systems (1)
- Diastereomeric Camphanoates (1)
- Dibenzophosphole (1)
- Dicer (1)
- Dictyostelium (1)
- Diels- Alder reaction (1)
- Different Forms (1)
- Differential Thermoanalysis (1)
- Differential equations (1)
- Dihydroquinolin-4-ones (1)
- Diisobutylaluminum Hydride (1)
- Dimerization (1)
- Dimethyl maleic anhydride (1)
- Dioxetanes (1)
- Direct carbon (1)
- Disease burden (1)
- Distance averaging (1)
- Disturbancies and mistakes (1)
- Donor/Acceptor-Complexes (1)
- Drift correction (1)
- Drug Resistance (1)
- Dynamic covalent chemistry (1)
- Dynamic networks (1)
- Dynamische Kernpolarisation (1)
- E. colo (1)
- E3 ligase (1)
- EDTA (1)
- EEC syndrome (1)
- EIGER detector (1)
- ENDOR (Special; General Triple) Spectra (1)
- ENDOR Couplings (1)
- ENDOR Spectra (1)
- ENDOR and Triple Spectra (1)
- EPR of Copper (II) Complexes with Membrane Proteins (1)
- EPR spectroscopy (1)
- ERAD (1)
- ESR Spectroscopy (1)
- ESR-spectra (1)
- ESR/ENDOR Measurements (1)
- EcNhaA (1)
- Echtzeit-NMR-Spektroskopie (1)
- Effect of Copper (II) (1)
- Electrochemistry (1)
- Electron Pair Interaction (1)
- Electron Paramagnetic Resonance (EPR) (1)
- Electron tomography (1)
- Electron transfer (1)
- Electronic Structure (1)
- Electronic Structures (1)
- Electrophysiology (1)
- Elektrophorese (1)
- Empfindlichkeitsverstärkung (1)
- Enantiospecific GC-Analysis (1)
- Endogene Carcinogenesis (1)
- Endogenous RNA-Polymerase (1)
- Endogenous RNA-Polymerase Activity (1)
- Endoplasmic reticulum (1)
- Ene Reaction (1)
- Entzündung (1)
- Enzymatic Behaviour (1)
- Enzymatic DNA Methylation (1)
- Enzymatic Methylation (1)
- Enzymatic decomposition (1)
- Enzyme Preparation (1)
- Enzyme-linked immunoassays (1)
- Enzymes (1)
- Eph receptors (1)
- Ephrin ligand (1)
- Escherichia coli (1)
- Ethene (1)
- Ethyne (1)
- Eukaryota (1)
- Evolution (1)
- Evolution/Protein (1)
- Exchange PAINT (1)
- Eyes (1)
- FF-ATP synthase dimer (1)
- FGFR (1)
- FIH1 (1)
- Fatty acid synthase (1)
- Fatty alcohol (1)
- Festkörper-DNP (1)
- Flavin (1)
- Flavin-binding Protein (1)
- Flavoproteins (1)
- Flightless-I (1)
- Flow chemistry (1)
- Fluorescence (1)
- Fluorescence correlation spectroscopy (1)
- Fluorine-Sulfur-Nitrogen Compounds (1)
- Fmoc solid phase peptide synthesis (1)
- Formaldehyde (1)
- Funding (1)
- G protein-coupled receptor (GPCR) (1)
- G quadruplex helicase RHAU (1)
- GCN (1)
- Gallium (1)
- Gas Phase Conformation (1)
- Gas Phase Dehydrochlorination (1)
- Gas Phase Pyrolysis (1)
- Gas Phase Thermolysis (1)
- Gasphase Pyrolyses (1)
- Gating (1)
- Gaussian Process (1)
- Gemischtvalente Verbindungen (1)
- Gene Regulation (1)
- Geranylgeranyl Pyrophosphate (1)
- Germane (1)
- Germoxane (1)
- Get Pathway (1)
- Glucose tolerance test (1)
- Glucosetoleranztest (1)
- Glyceraldehyde-3 Phosphate Dehydrogenase (1)
- Glyceraldehyde-3-phosphate Dehydrogenase (1)
- Gram‐negative (1)
- Grignard Reagents (1)
- Grignard reagent (1)
- Group II Aryls (1)
- Group III Alkyls (1)
- Guanine nucleotide exchange factors (1)
- Guanosine triphosphatase (1)
- H3 receptor (1)
- HCV (1)
- HDAC inhibitor (1)
- HGF (1)
- HIV-1 (1)
- HLA class I (1)
- HOX gene (1)
- Halbleitersilicium-Oberflächen (1)
- Half-of-the-Sites Reactivity (1)
- Halobacillus halophilus (1)
- Halogenation (1)
- Halogenobenzimidazoles (1)
- Halve-wave-potentials (1)
- Helicobacter pylori (1)
- Heterogeneous Catalysis (1)
- High Pressure Stability (1)
- High pressure (1)
- High-throughput screening (1)
- Hohes Magnetfeld (1)
- Huisgen cycloaddition (1)
- Hybrid Formation (1)
- Hydrogen Addition (1)
- Hydrolysis (1)
- Hydroquinone (1)
- Hyperconjugation (1)
- Hypersensitive Reaction (1)
- I50 Value (1)
- IN-VIVO (1)
- IR (1)
- IR-spectra (1)
- Identical Topology (1)
- Imido Complex of Tantalum (1)
- Iminophosphoranes (1)
- Immundiffusion (1)
- Immunodiffusion (1)
- Immunology (1)
- Immunoprecipitation (1)
- In vitro selection (1)
- Incidence (1)
- Induced pluripotent stem cells (1)
- Infrared Raman (1)
- Infrared Spectra (1)
- Inhibition of Photosynthetic Electron Transport (1)
- Insertion Reactions (1)
- Internal motion (1)
- Internal ribosome entry site (1)
- Intracellular Trafficking (1)
- Inverted DNA Repeats (1)
- Ion source (1)
- Ionic radii (1)
- Ionization State (1)
- Iron (1)
- Isocyanates (1)
- Isosterism (1)
- Isoxazoline Alkaloids (1)
- Kabachnik–Fields reaction (1)
- Kaurene (1)
- Ketene Imine (1)
- Kinase (1)
- Kinematic analysis (1)
- Kinetics of the Back Reaction (1)
- LAMTOR1 (1)
- LILBID (1)
- LIR interaction, (1)
- LOCKED NUCLEIC-ACID (1)
- LYR motif (1)
- LYR proteins (1)
- LYRM (1)
- Langlois reagent (1)
- Larvae (1)
- Lead Structure (1)
- Lewis Acid Base Interactions (1)
- Lewis acids (1)
- Library screening (1)
- Ligand-gated ion channel (1)
- Light (1)
- Light pulses (1)
- Lipid Organization (1)
- Liposomes (1)
- Lithium (1)
- Lithium-uranate(VI) (1)
- Lone Pair Electrons (1)
- Low Molecular Weight PTP (1)
- Luminescence (1)
- Luminescence Spectra Flash Photolysis (1)
- MAMMALIAN-CELLS (1)
- MLL1/2 (1)
- MO Interpretation (1)
- MO Models (1)
- MODIFIED OLIGONUCLEOTIDES (1)
- MYC (1)
- Major Histocompatibility Complex (MHC) (1)
- Malaria (1)
- Malate Dehydrogenases (1)
- Manganese (1)
- Manganese Binding Sites (1)
- Mannich-type bases (1)
- Mass spectrometry (1)
- Matricaria chamomilla L (1)
- Matricaria chamomilla L; (1)
- Matricine (1)
- Md simulations (1)
- MdfA (1)
- Melting Point (1)
- Melting Point Diagrams (1)
- Membrane Protein (1)
- Membrane Transport (1)
- Membrane protein complex (1)
- Membrane transport (1)
- Membrane-Phloretin Interaction (1)
- Membrane/Proteins (1)
- Mesenchymal stem cells (1)
- Met (1)
- Metabolite Transport (1)
- Metal Organic Derivates (1)
- Metal-Metal Multiple Bonds (1)
- Metallic radii (1)
- Metallic valence (1)
- Metalloenzymes (1)
- Metalloproteins (1)
- Methanogenesis (1)
- Methyleneaminoacetonitrile Monomer and Trimer (1)
- Methylmercury Containing Inactivator (1)
- Mikroelektronik-Technologie (1)
- Millisecond Luminescence of Chloroplasts (1)
- Mitochondrial and Cytoplasmic Malate Dehydrogenase (1)
- Mitochondrial proteins (1)
- Mixed Lipid Phases (1)
- Mixed Valence Nb-Se Complexes (1)
- Mixed-S tack Donor/Acceptor Complexes (1)
- MjNhaP1 (1)
- Mn(III)-Chlorin (1)
- Molecular Complexes (1)
- Molecular Conformation (1)
- Molecular Dynamics (1)
- Molecular Orbitals (1)
- Molecular Physiology of the Cell Membrane (1)
- Molecular Weight (1)
- Molecular chaperones (1)
- Molecular dynamics simulation (1)
- Molecular dynamics simulations (1)
- Molecular modelling (1)
- Molecular neuroscience (1)
- Molecular structure (1)
- Molecules with S·̱·̱̱·̱·̱·̱̱·̱N Bonds (1)
- Moleküldynamik (1)
- Molybdenum Bronce (1)
- Molybdenumnitridetrichloride-2.3.3-trichloroacrylnitrile (1)
- Monomers (1)
- Monomolecular Films (1)
- Motor neurons (1)
- MptpA (1)
- Mucopolysaccharidoses (1)
- Multidrug Transporters (1)
- Multiple Kernel (1)
- Multiple Transport Systems (1)
- Multivariate Analysis (1)
- Muscarinic Antagonists (1)
- Muscarinic Receptors (1)
- Muscle contraction (1)
- Muscle electrophysiology (1)
- Muscle fibers (1)
- Musculoskeletal disorder (1)
- Müller’s hydrocarbons (1)
- N,N'-Bis(trimethylsilyl)benzamidinato Complexes (1)
- N,O Ligands (1)
- N-Chloro-Nitrene-Molybdenum Tetrafluoride (1)
- N-Chloro-Nitrene-Tungsten Tetrachloride (1)
- N-Heterocycles (1)
- N-Sulfonylamide (1)
- N-Triflyl Phosphoramide (1)
- N-Trimethylsilyl-iminotriphenylphosphorane Copper(II) Chloride (1)
- N5 -methyl-tetrahydromethanopterin: coenzyme M methyltransferase (1)
- NACI (1)
- NAD + Analogues (1)
- NAD Analogs (1)
- NAD+-Analogs (1)
- NADP+ Analogues (1)
- NADPH oxidase (1)
- NAD⊕-Isomer (1)
- NAFLD (1)
- NASH (1)
- NBO analysis (1)
- NF-kappaB (1)
- NMR -spectra (1)
- NMR Spectroscopy (1)
- NMR crystallography (1)
- NMR spectrum (1)
- NMR structure determination (1)
- NMR-Spektroskopie (1)
- NOE (1)
- NOTCH (1)
- Na+ transport (1)
- Naja naja atra (1)
- Nanobody (1)
- Nanomedicine (1)
- Nascent RNA (1)
- Native mass spectrometry (1)
- Natural Quinones (1)
- Nerolidol (1)
- Nerve fibers (1)
- Neural pathways (1)
- Neurospora crassa (1)
- NhaA (1)
- Nitric oxide (1)
- Nitro Compounds (1)
- Nitromethane (1)
- Nitrosative Stress (1)
- Nitroso Compounds (1)
- Non-covalent mass spectrometry (1)
- Non-negative matrix factorization (1)
- Nuclear Overhauser effect (1)
- Nuclear magnetic resonance (1)
- Nucleoside Triphosphates (1)
- Nucleotide Triphosphate Analogue (1)
- N—H⋯O hydrogen bonds (1)
- O-H...[pi] interactions (1)
- OD approach (1)
- OH Radical (1)
- OTU domain-containing protein 7B (OTUD7B) (1)
- OXPHOS complexes (1)
- Octanoic acid (1)
- Olefins (1)
- Olfactoric Properties (1)
- Oligomeric State (1)
- Oligomers (1)
- One-Electron Oxidation (1)
- One-Electron Reduction of 9,9′-Bianthryl (1)
- One-Electron Reduction of Diphenoquinones (1)
- Opacity (1)
- Ophthalmology (1)
- Optical lenses (1)
- Optical tweezers (1)
- Optimally Solvated Sodium Cation (1)
- Organelle (1)
- Organoboranes (1)
- Organocatalysis (1)
- Organophosphorus Compounds (1)
- Organosulfur Radical Cations (1)
- Osmoregulation (1)
- Overhauser-Effekt (1)
- Oxidation States (1)
- Oxidoreductases (1)
- Oxo-and Alkylamino-Substituted p-Benzoquinone Derivatives (1)
- Oxocarboxylic Acids (1)
- P4 (1)
- PABP (1)
- PALM (1)
- PAR complex (1)
- PASSENGER-STRAND (1)
- PDZ domain (1)
- PE Assignment (1)
- PELDOR/DEER (1)
- PIDDosome (1)
- PPAR (Peroxisome proliferator-activated receptors) (1)
- PPARγ (1)
- PROTAC (1)
- Packing density (1)
- Pairwise Sequence Alignment (1)
- Palladium (1)
- Paracoccus denitrificans (1)
- Parasite immune evasion (1)
- Parasitic infection (1)
- Parkinson disease (1)
- Peak overlap (1)
- Peak picking (1)
- Pentafluorophenyl Derivatives (1)
- Peptides (1)
- Perfluoromethanimine (1)
- Personalisierte Medizin (1)
- Phage display (1)
- Pharmacodynamics (1)
- Phase diagrams (1)
- Phenols (1)
- Phosphonium Salts (1)
- Phosphoramide mustard (1)
- Photoaffinity Labeling (1)
- Photobiology (1)
- Photodecom position (1)
- Photoelectron Spectroscopy (1)
- Photofragmentations (1)
- Photooxidation (1)
- Photoreceptor (1)
- Phvtoene Desaturase (1)
- Phvtofluene (1)
- Phytoene (1)
- Pigment Yellow 181 (1)
- Plasmid mapping (1)
- Platelet physiology (1)
- Polarography (1)
- Polyacrylamid-Gel (1)
- Polyamides (1)
- Polyaromatic Hydrocarbons (1)
- Polycyclic Hydrocarbons (1)
- Polycyclic aromatic hydrocarbons (1)
- Polymerization (Polymers) (1)
- Polymorphs (1)
- Polypharmacology (1)
- Polyphenole (1)
- Polyunsaturated fatty acid mediators (1)
- Potassium channels (1)
- Potassium transport (1)
- Preparation (1)
- Primary hemostasis (1)
- Primary metabolites (1)
- Programme Cell Death (1)
- Proteases (1)
- Proteasome (1)
- Protein Domains (1)
- Protein Dynamics (1)
- Protein Structure (1)
- Protein Structure and Dynamics (1)
- Protein design (1)
- Protein structure (1)
- Protein translation (1)
- Protein/Sorting (1)
- Protein/Targeting (1)
- Protein/Translocation (1)
- Proteins (1)
- Proteolysis (1)
- Proteostasis (1)
- Proton Transfer (1)
- Proton Transfer Kinetics (1)
- Proton Transport (1)
- Proton pumping (1)
- Pseudo Jahn-Teller-Effect (1)
- Psoriasis (1)
- PtkA (1)
- Pulsed epr (1)
- Pyridazine (1)
- Pyridinium Bromide (1)
- Pyridinium Iodide (1)
- Pyridinium chloride (1)
- Pyruvate Kinase (1)
- Quantum Chemical Calculations (1)
- Quantum chemistry (1)
- Quinhydrone (1)
- RNA hairpin (1)
- RNA in zebrafish brain (1)
- RNA induced silencing complex (1)
- RNA jepit rambut (1)
- RNA processing (1)
- RNA recognition (1)
- RNA recognition motif (1)
- RNA sequencing (RNA-Seq) (1)
- RNA stability (1)
- RNA stem-loop structure (1)
- RNA-DNA-Hybridization (1)
- RNA-Polymerase Binding (1)
- RNA-protein complex (RNP) (1)
- RNASolution-state NMR (1)
- RNActive (1)
- RND (1)
- RNP dynamics (1)
- RRM domain (1)
- RXRα (1)
- Rab7 (1)
- Rac1 (1)
- Radical Anion Sodium Salt (1)
- Radical Anions (1)
- Radical Cation (1)
- Radical Cations (1)
- Radical Contact Ion Pairs (1)
- Radical Ions (1)
- Radicals (1)
- Ragulator complex (1)
- Raman Spectroscopy (1)
- Raman-spectra (1)
- Rap1 (1)
- Reaction products (1)
- Reassociation Kinetics (1)
- Receptor Tyrosine Kinase (1)
- Reconstitution of Membrane Transporters (1)
- Redox-linked Proton Pump (1)
- Redoxactive Ligands (1)
- Reduction by R4N®BH4e (1)
- Reduction of 1-Sila-2,5-diazacyclopentane-3,4-dithione and of Tetrakis(isopropylthio)-p-benzoquinone (1)
- Registration (1)
- Reinheit (1)
- Reinigung (1)
- Research trends (1)
- Resonance Raman spectroscopy (1)
- Resonance assignment (1)
- Reticulon (1)
- Retinal (1)
- Rhenium(VII) (1)
- RhoA (1)
- RhoGTPases (1)
- Ribonucleosides (1)
- Ribosome (1)
- Ribosome display (1)
- Rieske domains (1)
- Rpo4/7 (1)
- Rtn3 (1)
- Ruthenium Complexes (1)
- Rydberg transitions (1)
- S. Cerevisiae (1)
- SAP domain (1)
- SAXS (1)
- SEC-MALS (1)
- SF3b145 (1)
- SF3b49 (1)
- SILAC-based proteomics (1)
- SMALL INTERFERING RNA (1)
- SSR128129E (1)
- STED superresolution (1)
- STRUCTURAL BASIS (1)
- Saccharomyces cerevisiae (1)
- Salicylic Acid (1)
- Salmonella Typhimurium (1)
- Salmonella typhimurium (1)
- Salmonella-induced filaments (1)
- Scribble (1)
- Secondary metabolites (1)
- Selective autophagy (1)
- Selenium Compounds (1)
- Selenium Organic Compounds (1)
- Seleniumphosphoryl-compounds (1)
- Separation of ADP-Binding Enzymes (1)
- Shift-Reagents (1)
- Shine-Dalgarno (1)
- Short-chain fatty acids (1)
- Short-lived Intermediates (1)
- SiN Double Bond (1)
- Signal Transduction (1)
- Signal processing (1)
- Signal transduction (1)
- Sila-difenidol (1)
- Sila-pridinol (1)
- Silanimine (1)
- Silver (1)
- Silyl Amine (1)
- Silylamide (1)
- Single molecule force spectroscopy (1)
- Single-molecule localization microscopy (1)
- Single-molecule photobleaching (1)
- Sinorhizobium fredii (1)
- Small Rings (1)
- Small molecules (1)
- Soap Solutions (1)
- Sodium (1)
- Sodium -15-crown-5-pentafluoro-N-chloronitreno-tungstate(VI) (1)
- Sodium Metal Reduction (1)
- Sodium Proton Exchange (1)
- Sodium-15-crown-5-pentafluoro-N-chloronitreno-molybdate(VI) (1)
- Solid Supported Membrane (1)
- Solid supported membrane (1)
- Soluble epoxide hydrolase (1)
- Soluble gp140 Env (1)
- Soluble proteins (1)
- Solvation Effects (1)
- Solvent-Separated Radical Ion Pair (1)
- Solvents (1)
- Soybean (1)
- Specific Synthesis (1)
- Spin Trap (1)
- Spiro Compounds (1)
- Sponges (1)
- Spontaneous Reduction of Mn(IV)-chlorin (1)
- Squalene (1)
- Sr2CO4 (1)
- SseJ (1)
- Ste2p (1)
- Stem-cell differentiation (1)
- Sterically Overcrowded Organosilicon Molecules (1)
- Sterols (1)
- Stilbene (1)
- Stoffwechsel (1)
- Stress response (1)
- Structural Changes (1)
- Structural and Conformational Changes (1)
- Structural biology (1)
- Structural biology and molecular biophysics (1)
- Structure Elucidation (1)
- Störmöglichkeiten und Fehlermöglichkeiten (1)
- Subcellular Organelles (1)
- Substituents (1)
- Substitution of Ribose (1)
- Subvalent Main Group Metals (1)
- Subvalent compounds (1)
- Sulfhydryl Groups (1)
- Sulfur (1)
- Sulfur Dioxide (1)
- Sulfur-nitrogen Ring Systems (1)
- Sumoylation (1)
- Support Vector Regression (1)
- Support Vector Regression Model (1)
- Symmetry Properties (1)
- Syntheses (1)
- Synthetic methods (1)
- TATU (1)
- TBMP (1)
- TEMPO (1)
- TLS refinement (1)
- Tail-anchored Proteins (1)
- Targeted drug delivery (1)
- Tellurates (1)
- Tellurium Organic Compounds (1)
- Temperature Dependence (1)
- Testosterone (1)
- TetR family (1)
- Tetra(2'-pyridyl)pyrazine (1)
- Tetra(methylthio)thiophene (1)
- Tetrabenzoato-tetrachloro-dimolybdate (1)
- Tetraether Lipids (1)
- Tetraketone Radical Anion (1)
- Tetranuclear Ti Cluster (1)
- Tetraphenyl-p-benzoquinone Reduction (1)
- Tetraphenyl-p-quinodimethane Dianion (1)
- Tetraphenylbutatriene Radical Anion and Dianion Salts (1)
- Tetrastigma voinierianum (1)
- Thalassiosira Pseudonana (1)
- Thermal Retrotrimerization (1)
- Thermal motion (1)
- Thermodynamic Excess Functions (1)
- Thermodynamic excess functions (1)
- Thermoplasma acidophilum Membranes (1)
- Thermoplasma acidophilum Membranes; Tetraetherlipids (1)
- Thienylidene Complexes (1)
- Thiocarbonates (1)
- Thiolate Ligands (1)
- Thionitrosyl Complexes (1)
- Time-resolved Absorption Spectroscopy (1)
- Titanium (1)
- TolC (1)
- Tolbutamide-test (1)
- Tolbutamidtest (1)
- Tools and resources (1)
- Tools and ressources (1)
- Topology (1)
- Totalreflexions-Röntgenfluoreszenz-Spektrometrie (1)
- Transcriptional Control (1)
- Transcriptomics (1)
- Translation initiation (1)
- Transporter (1)
- Transporters (1)
- Triazene (1)
- Tricyanomethane Derivatives (1)
- Tridentate Ligands (1)
- Triel (1)
- Trifluoromethoxy groups (1)
- Trifluoromethyl Derivatives (1)
- Trifluoromethylazide (1)
- Trigonal Prismatic Pd-Se Cluster (1)
- Trimethylchloromethane (1)
- Trimethylchlorosilane (1)
- Trimethyltin Chloride (1)
- Triphenylmethylphosphonium Nitrite and Formate (1)
- Triphenylphosphane (1)
- Tuberculosis (1)
- U V /V IS Spectra (1)
- U2 snRNP (1)
- UBA domain (1)
- UBA5 (1)
- UFC1 (1)
- UFM1 (1)
- USP28 (1)
- USP32 (1)
- UV spectra (1)
- Ubiquitin (1)
- Ubiquitination (1)
- Ultrafast Spectroscopy (1)
- Umpolung (1)
- V3 loop (1)
- VEGF (1)
- Valence (1)
- Valence State (1)
- Ventricular tachycardia (1)
- Vesicles (1)
- Vibronic Coupling (1)
- Vinyl Azide (1)
- Viral Immunology (1)
- Virtual drug screening (1)
- Visual acuity (1)
- Visual impairments (1)
- Volmer–Weber growth (1)
- WL110547 (1)
- Wang resin (1)
- Western blot (1)
- Wnt (1)
- X-Ray Crystal Structures of Co- and Mn-Clusters (1)
- X-Ray Crystallography (1)
- X-Ray Structure (1)
- X-ray Crystallography (1)
- X-ray crystal structure determination (1)
- X-ray detectors (1)
- XRPD (1)
- X‐ray diffraction (1)
- Y10B (1)
- Yarrowia lipolytica F1Fo-ATP synthase (1)
- Zellstudien (1)
- Zinc (1)
- Zirconium (1)
- [pi]-[pi] interaction (1)
- a-proteobacteria (1)
- abnormality detection (1)
- absolute configuration (1)
- acetyl-CoA (1)
- acridine orange (1)
- actomyosin (1)
- adaptive immunity (1)
- aggregation (1)
- air pollution (1)
- airborne bacteria (1)
- alanylphenylalanyl derivative (1)
- alkali and alkaline earth metal salts (1)
- alkaloids (1)
- alkylation (1)
- all-optical electrophysiology (1)
- allergy (1)
- alpha toxin (1)
- amino acids (1)
- amoeboid (1)
- amorphous stability (1)
- amphipols (1)
- anaerobic energy metabolism (1)
- analysis (1)
- anthrone (1)
- antibacterial activities (1)
- antibiotic transporters (1)
- anticoagulants (1)
- anticonvulsant activity (1)
- antigen processing (1)
- archaellum (1)
- argonaute protein (1)
- aromatics (1)
- artificial ribonuclease (1)
- asthma (1)
- asymmetry (1)
- atopy (1)
- auto-inhibition (1)
- automatic environmental tobacco smoke emitter (1)
- automation (1)
- aza-Michael Addition (1)
- azo compounds (1)
- bacterial resistance mechanisms (1)
- beam-induced movement (1)
- benzoxazine (1)
- binding affinity (1)
- binding sites (1)
- bioenergetics (1)
- biological chemistry (1)
- biological macromolecules (1)
- biological models (1)
- biophysical investigation (1)
- biophysics and structural biology (1)
- biosenors (1)
- biotin (1)
- blood coagulation (1)
- borane (1)
- bromodomain (1)
- cGMP (1)
- cIAP1 (1)
- cIAP1 BIR (1)
- caged ATP (1)
- caged diacylglycerol (1)
- cancer (1)
- car indoor (1)
- carbenium ions (1)
- carbodiimide (1)
- carbon and proton assignments (1)
- carbon oxides (COx) (1)
- carcinogenesis (1)
- cardiolipin (1)
- caspase-2 (1)
- catabolism (1)
- cell biology (1)
- cell death (1)
- cell migration (1)
- cell proliferation (1)
- cell studies (1)
- cell-free expression (1)
- cellular rosette (1)
- cellular self-organization (1)
- centrosome (1)
- centrosome linker (1)
- channelrhodopsin (1)
- chemical bonding (1)
- chemical signaling (1)
- chemical vapor deposition (1)
- chemical vapour deposition (1)
- chemical-induced proximity (1)
- chemotaxis (1)
- chloroplast membrane proteins (1)
- chlorosilane (1)
- cholesterol-dependent cytolysin (cdc) (1)
- chromatin (1)
- chromatin remodeling (1)
- chronic myeloid leukemia (1)
- chymotrypsin inhibitor (1)
- cigaret smoke (1)
- cigarette strength (1)
- circular dichroism (1)
- cis`-Phytoene (1)
- citrate transport (1)
- clathrin heavy chains (1)
- cleavage of large RNA molecules (1)
- cleavage site selection (1)
- click azide-alkyne (1)
- co-crystal (1)
- coagulation process (1)
- cocrystalline adducts (1)
- cocrystals (1)
- cofactor recruitment (1)
- collagen VI (1)
- colorectal cancer (1)
- colorimetric signals (1)
- combinatorial biosynthesis (1)
- combined therapy (1)
- compatible solutes (1)
- complex III2 (1)
- complex structure (1)
- complexity (1)
- computational modeling (1)
- conformation analysis (1)
- conformational changes (1)
- conformational dynamics (1)
- conformational flexibility (1)
- conformational heterogeneity (1)
- conformational space (1)
- cooperativity (1)
- correlated dynamics (1)
- correlations (1)
- cortical flow (1)
- costimulation (1)
- coumarin-4-ylmethyl (1)
- cryo-electron microscopy (1)
- cryo-electron tomography (1)
- cryoEM (1)
- cryoelectron microscopy (1)
- cryoem (1)
- cryoet (1)
- crystal engineering (1)
- crystal structure determination (1)
- cupriavidus necator (1)
- cyclic compounds (1)
- cyclization (1)
- cycloaddition (1)
- cytarabin (1)
- cytochrome c oxidase (1)
- cytochromes (1)
- dNTP hydrolysis (1)
- dNTP pool sanitizing enzymes (1)
- dNTPase inhibitor (1)
- dSTORM (1)
- data-collection strategy (1)
- decachlorocyclopentasilanes (1)
- dehydrogenases (1)
- denisovite (1)
- density functional calculations (1)
- designed multitarget ligands (1)
- detection (1)
- deubiquitylation (deubiquitination) (1)
- development (1)
- devitrification (1)
- diMannich base (1)
- diagnostic radiologic examination (1)
- difference spectra (1)
- diffusion dynamics (1)
- digital twin (1)
- disorder (1)
- dispersion-corrected density functional theory (1)
- disulfide bond isomerization (1)
- dithiourea (1)
- divalent metal ions (1)
- dna (1)
- docking domains (1)
- domino reactions (1)
- drug design (1)
- drug target (1)
- dsRNA (1)
- dual BET/HDAC inhibitor (1)
- dual nucleic acid binding (1)
- dye labeling (1)
- dynein (1)
- efflux pumps (1)
- eicosanoid (1)
- electrochemical CO2 reduction (1)
- electrochromic FRET (1)
- electron cryo-microscopy (cryoem) (1)
- electron cryo-tomography (cryoet) (1)
- electron cryomicroscopy (1)
- electron cryotomography (1)
- electron crystallography (1)
- electron diffraction tomography (1)
- electron microscopy (1)
- electron tomography (1)
- electron-beam lithography (1)
- embryologic development (1)
- enamides (1)
- endocytosis (1)
- endophilin (1)
- endosomal tubulation (1)
- enhancer (1)
- entropy (1)
- envelope membrane proteome approach comparison (1)
- enzymes (1)
- eph receptor tyrosin kinase family (1)
- ephrins (1)
- epidermis (1)
- epigenetic (1)
- exact NOE (1)
- excitation transport (1)
- excited molecules (1)
- f-MLF (1)
- fatty acid synthases (1)
- fatty acid synthesis (1)
- fatty-acid synthase (1)
- fatty-acid synthesis (1)
- fertility (1)
- fibrous materials (1)
- field-effect transistor (1)
- fluorescence (1)
- fluorescence dye (1)
- fluorescent proteins (1)
- fluorinated compounds (1)
- folding (1)
- formate (1)
- formylation (1)
- framework-structured solids (1)
- fungi (1)
- fusion (1)
- gait adaptation (1)
- gastric cancer (1)
- gastrulation (1)
- gene expression regulation (1)
- genetic analysis (1)
- genetic predisposition (1)
- genome editing (1)
- glass forming ability (1)
- glutaconyl-CoA decarboxylase (1)
- glutamine synthetase (1)
- glycoproteins (1)
- gold (1)
- graphene (1)
- guanosine (1)
- halophile (1)
- heart (1)
- heterodimer (1)
- heterologous expression (1)
- heteronuclear detection (1)
- hexahydropyrimidine (1)
- hexahydropyrimidine (1)
- high molecular weight plasticizer (1)
- histamine (1)
- histone acetylation (1)
- homodimer (1)
- homogeneous time-resolved FRET (HTRF) (1)
- hotmelt extrusion (1)
- hotochromism (1)
- humectant agents (1)
- hydrate (1)
- hydrazide (1)
- hydroxylation (1)
- hydroxynaphthoquinone (1)
- hyperconjugation (1)
- hyperconjugative interaction (1)
- imadazolidine (1)
- imidazole (1)
- imidazolidine (1)
- immunity (1)
- in-cabin exposure (1)
- in-vitro Assay (1)
- inhibition (1)
- inhibitor (1)
- inhibitor design (1)
- inhibitors (1)
- inner membrane morphology (1)
- inorganic materials (1)
- inositol (1)
- insulin resistance (1)
- internalin B (1)
- intramolecular hydrogen bond (1)
- intramolecular hydrogen bond (1)
- inverse-sandwich complex (1)
- iodine (1)
- ion translocation (1)
- ion treatment (1)
- ions (1)
- iron-sulfur proteins (1)
- irradiation-promoted exchange reaction (1)
- irrigation (1)
- isilane cleavage (1)
- isocyanate (1)
- isomeric antagonists (1)
- isomerization mechanisms (1)
- isothermal titration calorimetry (ITC) (1)
- isothiocyanate (1)
- isotope labeling (1)
- jumping crystals (1)
- kinesin (1)
- kinetic resolution (1)
- kinetically trapped state (1)
- lantibiotic (1)
- large functional RNAs (1)
- layer-by-layer (LbL) (1)
- leaf patch clamp pressure (1)
- leukocyte-endothelial cell interaction (1)
- liana (1)
- ligand binding (1)
- ligands (1)
- light harvesting networks (1)
- light-gated ion channel (1)
- light–energy conversion (1)
- lipase (1)
- lipoic acid (6,8-dithio-octanoic acid) (1)
- lipoprotein (1)
- lipoproteins (1)
- lithium chloride (1)
- lithium hydride (1)
- local radiotherapy (1)
- locked nucleic acids (1)
- locomotion (1)
- lysozyme (1)
- mRNA (1)
- mRNA translation (1)
- mRNA vaccine (1)
- mTORC1 (1)
- machine learning (1)
- macromolecular complexes (1)
- macromolecular crystallography (1)
- macrophage polarization (1)
- macrophages (1)
- magic angle spinning (1)
- magic-angle spinning (1)
- magnetic measurements (1)
- magnetic properties (1)
- major facilitator superfamily (1)
- mammals (1)
- mass spectrometry (1)
- maternal tobacco smoke (1)
- matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (1)
- md simulations (1)
- mechanochemical synthesis (1)
- mechanochemistry (1)
- megasynthases (1)
- melting point (1)
- membrane curvature (1)
- membrane pore (1)
- membrane proteome (1)
- menthol (1)
- mesenchymal (1)
- mesopore (1)
- mesoporous silica (1)
- messenger (1)
- meta-stable structures (1)
- metabolic enzyme engineering (1)
- metabolic reprogramming (1)
- metal organic derivatives (1)
- metal-ion translocation (1)
- metals (1)
- metal–organic frameworks (1)
- metastases (1)
- methylene derivatives (1)
- miRNA (1)
- mice (1)
- microbial electrosynthesis (1)
- microbiology and infectious disease (1)
- microcontact printing (1)
- microenvironment (1)
- microwave-assisted synthesis (1)
- migration (1)
- minerals (1)
- mitochondrial acyl-carrier protein (1)
- mitochondrial fatty acid synthesis type II (1)
- mitogenic effects (1)
- mobile air quality study (1)
- modularity (1)
- modularity of megasynthases (1)
- molecular conformation (1)
- molecular machines (1)
- molecular motors (1)
- molecular tug-of-war (1)
- molecular co-crystal (1)
- monosilanes (1)
- morphogenesis (1)
- mouse (1)
- mouse model (1)
- multi-drug-resistant pathogens (1)
- multi-network (1)
- multidomain protein (1)
- multidrug resistance (1)
- multidrug transport (1)
- multiple sclerosis (1)
- multiplexing (1)
- muscle activity (1)
- muscular dystrophies (1)
- musculoskeletal radiographs (1)
- mycolic acid (1)
- n-Ionizations (1)
- nESI (1)
- nRNA Complexity (1)
- nanocrystalline materials (1)
- nanoparticle (1)
- nanoscience (1)
- nanostructure (1)
- negative-stain electron microscopy (1)
- neuromuscular (1)
- neuronal RNA (1)
- neuronal synapse (1)
- neurons (1)
- newly synthesized RNA (1)
- nisin binding (1)
- nitrogen oxides (NOx) (1)
- non-alcoholic steatohepatitis (1)
- non-conventional hydrogen bonds (1)
- non-ribosomal peptide synthetases (1)
- non-small cell lung cancer (1)
- non-uniform sampling 2 (1)
- noncovalent interactions (1)
- nor-N-mustard (1)
- nuclear magnetic resonance (1)
- nuclear matrix (1)
- nuclear receptor (1)
- nucleic acids (1)
- nucleotides (1)
- oligonucleotide (1)
- oligosilanes (1)
- oocyte death (1)
- oocytes (1)
- open quantum systems (1)
- open structure (1)
- open-cube cluster (1)
- optogenetic stimulation (1)
- organic pigment (1)
- organic synthesis (1)
- organic thin films (1)
- organophosphate flame retardants (OFR) (1)
- orthocarbonates (1)
- osmoregulation (1)
- overview (1)
- oxazine (1)
- oxidases (1)
- oxylipin (1)
- p-hydroxyphenacyl (1)
- p53 family (1)
- p73 (1)
- pH Indicator Dye (1)
- pH Regulation (1)
- pancreatic ductal adenocarcinoma (1)
- paramagnetic effects (1)
- particle size distribution (1)
- particulate matter (PM) (1)
- passive smoke (1)
- patterning (1)
- pearling transition (1)
- peptide editing (1)
- peptides (1)
- perlakuan ion (1)
- personalized medicine (1)
- phagocytosis (1)
- phase transitions (1)
- phase-shift (1)
- phenylsilane (1)
- phosphate homeostasis (1)
- phosphate translocation mechanism (1)
- phosphate transport regulation (1)
- phosphate transporter (1)
- phosphorus (1)
- phosphorus organic compounds; (1)
- phosphorus-fluoro compounds (1)
- phosphorylation (1)
- photoacid generator (1)
- photochromism (1)
- photodynamic effect (1)
- photoelectron spectra (1)
- photolabile protection (1)
- photolysis (1)
- photooxidation (1)
- photoswitchable organic fluorophores (1)
- photoswitches (1)
- phylogeny (1)
- planar polarity (1)
- plant proteomics (1)
- plant symbioses (1)
- plasmid copy number (1)
- plasticity (1)
- polyhydroxy (1)
- polyketide synthase (1)
- polyketide synthases (1)
- polynaphthoxazine materials (1)
- polysilane (1)
- polytypism (1)
- portable electronic nose (1)
- posttranslational modification (PTM) (1)
- precision (1)
- primary active transporters (1)
- prostacyclin (1)
- prostaglandin (1)
- prostaglandins (1)
- protein aggregation (1)
- protein assembly (1)
- protein design (1)
- protein dynamics (1)
- protein engineering (1)
- protein evolution (1)
- protein folding (1)
- protein phosphorylation (1)
- protein structure (1)
- protein structure determination 1 (1)
- protein tyrosine kinase (1)
- protein-protein interaction (1)
- protein-protein interactions (1)
- protein–protein interaction (1)
- proteomics (1)
- proton transfer (1)
- protons (1)
- pull-down (1)
- quantum transport (1)
- quinazoline ribonucleosides (1)
- quinazolinone alkylation (1)
- quorum sensing (QS) (1)
- radiation-induced nanostructure (1)
- ratiometric (1)
- real-time NMR spectroscopy (1)
- receptor tyrosine kinases (1)
- recycling pathway (1)
- reductases (1)
- reflectance spectra (1)
- regioisomers (1)
- relapsing-remitting (1)
- remote Carbenes (1)
- remote control (1)
- resistance–nodulation–cell division (RND) (1)
- resolution (1)
- respirasomes (1)
- respiratory chain (1)
- respiratory chain supercomplexes (1)
- respiratory complex I (1)
- respiratory complex IV (1)
- response regulator (1)
- retrograde transport (1)
- ribonucleases (1)
- ribosomal binding site (1)
- ribosome (1)
- ribosome quality control (1)
- riboswitches (1)
- rna recognition motif (1)
- roentgen rays (1)
- rootletin (1)
- rotary ATPase mechanism (1)
- rotator phase (1)
- rotaxane shuttling (1)
- sORF (1)
- salmonella (1)
- scaffold attachment factor proteins (1)
- second-hand smoke (1)
- secondary chemical shifts (1)
- secondary transporter (1)
- selective autophagy receptor (1)
- selective isotopic labeling (1)
- selenolates (1)
- self-assembled monolayer (1)
- self-assembled monolayers (1)
- semi-thin brain tissue sections (1)
- semiconductors (1)
- sequence alignment (1)
- short linear motifs (SLiMs) (1)
- signal transduction (1)
- silane (1)
- silica (1)
- silicon (1)
- silicon chips (1)
- silicon derivatives (1)
- silicon nanowires (1)
- silver salt (1)
- simulasi DM (1)
- single molecule (1)
- single particle (1)
- single particle analysis (1)
- single-crystal X-ray diffraction (1)
- single-molecule analyses (1)
- single-molecule förster resonance energy transfer (smFRET) spectroscopy (1)
- single-molecule localization microscopy (1)
- single-particle averaging (1)
- single-particle cryo-EM (1)
- single-particle tracking with photoactivated-localization microscopy (1)
- singlet oxygen (1)
- singlet oxygen (1Δg) chemiluminescence (1)
- single‐molecule tracking (1)
- site-directed mutagenesis (1)
- size of cigarettes (1)
- skeletal muscle (1)
- skin (1)
- small angle x-ray scattering (1)
- small gene (1)
- small protein (1)
- smoking in pregnancy (1)
- snake venom (1)
- sodium-proton exchange (1)
- solid-state NMR spectroscopy (1)
- solid-state nanopores (1)
- soluble epoxide hydrolase (1)
- solvents (1)
- specialized pro-resolving mediator (1)
- specificity of cleavage (1)
- spectroscopy (1)
- spectrum (1)
- spectrum analysis (1)
- spectrum reconstruction 3 (1)
- spermidine (1)
- spliceosome (1)
- spring-loaded activation (1)
- squamous cell carcinoma (1)
- ssFLYA (1)
- stability (1)
- stacking (1)
- stereoselective synthesis (1)
- stereoselectivity (1)
- stratified epithelial tissues (1)
- structural biolog (1)
- structural biology and molecular biophysics (1)
- structural calculation 4 (1)
- structural investigations (1)
- structure calculation (1)
- structure determination (1)
- structure ensemble (1)
- structure-property relationship (1)
- structure/function analysis (1)
- substrate-binding site (1)
- substrate-bound state (1)
- sumoylation (1)
- super-resolution (1)
- super-resolution microscopy (1)
- super-structure (1)
- superbugs (1)
- superresolution microscopy (1)
- supersaturation (1)
- support vector machine (1)
- supramolecular chain (1)
- supramolecular chemistry (1)
- surface chemistry (1)
- surface-attached metal–organic framework (1)
- surface-mounted metal–organic frameworks (SURMOFs) (1)
- syn conformation (1)
- synaptic vesicles (1)
- synthetic riboswitches (1)
- tapasin (1)
- telomerase (1)
- temperature (1)
- tetracycline (1)
- tetracycline aptamer (1)
- tetracycline transporter (1)
- tetrahydroisoquinoline (1)
- tetrahydropyrans (1)
- tetramerization (1)
- thermometers (1)
- thiolates (1)
- thiophenylazobenzene (1)
- thiostrepton (1)
- thrombin (1)
- thromboxane (1)
- tigecycline (1)
- time-resolved spectroscopy (1)
- tissue imaging (1)
- titration method (1)
- traffic emissions (1)
- trans-Hexafluoroazomethane (1)
- transacylation (1)
- transcription (1)
- transcription repressor (1)
- transcriptional activity (1)
- transfer function (1)
- translation initiation region (1)
- triaminodihydropyrimidinone (1)
- tripartite efflux pumps (1)
- triphenylmethyl ions (1)
- triptycene (1)
- tropism (1)
- tuberculosis (1)
- tumor angiogenesis (1)
- tumor hypoxia (1)
- tumor perfusion (1)
- tumour (1)
- turgor pressure (1)
- turgor pressure probe (1)
- twinning (1)
- tyrosine kinase inhibitors (1)
- tyrosine kinase inhibitors. (1)
- tyrosine kinase signaling (1)
- ubiquitin chain conformation (1)
- ubiquitination (1)
- uridine (1)
- urotropine (1)
- v-ATPase (1)
- valence (1)
- valences (1)
- vapor-liquid-solid mechanism (1)
- vapor–liquid–solid mechanism (1)
- ventilation modes (1)
- visualization of RNA (1)
- volatile organic compounds (VOC) (1)
- voltage imaging (1)
- von Willebrand factor (1)
- water solubility (1)
- wheezing (1)
- wine (1)
- x-ray crystallography (1)
- xefoampeptides (1)
- ΔNp63 (1)
- α-Aminophosphonates (1)
- α-Iminoketones (1)
- β -Diketiminate (1)
- β-Chloroethyl Azide (1)
- β-ᴅ-2′-Deoxyribosides (1)
- ζ-Carotene (1)
- μ-Nitrido Complexes of Tungsten(V) (1)
- π Conjugation (1)
- π Perturbation (1)
- π-Interactions (1)
- π-clamp (1)
- π–π stacking (1)
Institute
- Biochemie und Chemie (1110) (remove)
W2NCl7 has been prepared by the reaction of tungsten pentachloride with the bromide of Millon's base, [Hg2N]Br, in boiling CCl4. The product forms a dark brown, moisture sensitive crystal powder (μeff = 0.7 B.M. at 21 °C). With phosphoryl chloride, the complex W2NCl7·2 POCl3 is formed. The reaction with chlorine leads to the mixed-valenced W(V)/W(VI) complex W2NCl8 (μeff = 0.5 B.M. at 22 °C), which reacts with tetraphenylphosphonium chloride in CH2Cl2 to form (PPh4)2[W2NCl10] ·2CH2Cl2. The reactions of W2NCl7 with PPh4Cl in molar ratios in CH2Cl2 solution lead to several complexes; one of them was identified bv X-ray diffraction methods to be (PPh4)2[W3Cl9(μ3-N)(0)(μ2-NCl)]2 ·1,5 CH2Cl2, which forms black crystals. The compound crystallizes monoclinically in the space group P21/n with two formula units per unit cell (7318 observed, independent reflexions, R = 0.083). The lattice dimensions are (20 °C): a = 994.4; b = 2673; c = 1518.2 pm; β = 101.00°. The compound consists of PPh4⊕ cations and centrosymmetric anions [W3Cl9(μ3-N)(O)(μ2-NCl)]22⊕. The tungsten atoms form a scalene triangle with WW bond lengths of 282 and 278 pm, respectively. The hypothenuse of this triangle is a nearly linear W - N -W bridge with WN distances of 199 and 182 pm. One of the WW edges is bridged by a μ-NCI group with WN bond lengths of 196 und 189 pm. respectively.
Carbene transfer from aliphatic diazoalkanes upon coordinatively unsaturated metal centers is a general synthetic concept that provides straight-forward routes into organo-metallic hydrocarbon chemistry. A comparison focussing on several key reactions of general applicability demonstrates that mononuclear organometal substrates add carbenes that may act as bridging ligands (e.g., compound 6) if they arise from ω,ω'-bisdiazoalkanes. By way of contrast, metal-metal double bonds cleanly form dimetallacyclo-propane-type derivatives under very mild conditions (7-9). The broadest variety of structures is finally encountered with metal-metal triply bonded precursors such as the molybdenum compounds 3: here, the initial diazoalkane adducts are subject to further rearrangement processes commonly leading to metal-metal single bonds (11) or causing irreversible cleavage of the dinuclear metal systems (10).
The syntheses of the dibenzoquinolizinium-salts 3, 13, 16, 20 and 25 which are of spectroscopic interest are described. Their electronic excitation spectra will be published later by Perkampus and coworkers in this journal.
Über Reaktionen von 3-trifluormethylphenylsubstituierten silicium-und zinnorganischen Verbindungen
(1978)
Several routes were investigated for the preparation of 3-CF3C6H4N[Si(CH3)3]2 2 and 3-CF3C6H4N[Sn(CH3)3]2 3. The latter compound reacts with 3-CF3C6H4NCO to yield [3-CF3C6H4(CH3)3SnN]2CO 4. A substituted urea 5 is also formed from [(CH3)3Si]2NCH3 and 3-CF3C6H4NCO. 5 is used for the preparation of cyclic compounds, with S2Cl2 the ten-membered ring (3-CF3C6H4NCONCH3S2)2 6 is formed. 5 and HN(SO2Cl)2 yield the six-membered ring 3-CF3C6H4NCONCH3(SO2)2NH 7. SeOCl2 and 5 react under formation of a spiro compound (S-CF3C6H4NCONCH3)2Se 8. The compounds were characterized on the basis of mass and 19F NMR spectra.
Interactions of eosin with three different substrates, β-lactoglobuline, bovine serum albumin and cysteine, in aqueous solutions of pH 7 under illumination with light of wavelengths 5200—5400 Å are investigated by changes in absorption spectrum characteristics, SH-group activities and phosphorescence intensities.
Only with bovine serum albumin the major part of protein conversion, as shown by spectral changes and diminution of SH-groups due to eosin-sensitized photo-oxidation. In β-lactoglobuline an oxidizing photoreaction occurs, by which eosin is vanishing to the same degree as the protein shows loss of SH-groups and spectral alterations indicating attack on aromatic amino acid residues. There is no red shift of the eosin absorption band at 5170 Å as is observed in solutions of bovine serum albumin, where the intensity of phosphorscence is about 100 fold compared with the intensity obtained by solutions of β-lactoglobulin.
The aerobic eosin photoreaction in solutions of β-lactoglobulin is faster than aerobic photobleaching of the dye. Still faster is its bleaching photoreaction with cysteine, which is nearly independent of oxygen.
Über Natriumhexaoxometallate
(1969)
Über Lithiumhexaoxometallate
(1969)
Über Li6ReO6
(1969)
Es werden Schwingkreismodelle angegeben, deren Säkulargleichungen mit denen formal identisch sind, die sich bei der Anwendung der Methode der Moleküleigenfunktionen auf das Problem der π -Elektronenzustände in Molekülen ungesättigter und aromatischer Kohlenwasserstoffe ergeben. Damit ergibt sich die Möglichkeit, die quantenmechanischen Säkularprobleme durch Messung der Eigenfrequenzen der Modelle zu bestimmen.
The current definitions of isosterism are incomplete if excited species are considered; here any reasonable definition must include the specification of the valence state too. Implications of this are discussed. A criterion for the selection of consistent valence state energies is developed.
Die Resultate des vorstehend 1 veröffentlichten Näherungsverfahrens zur quanten-mechanischen Berechnung der Energie des π-Elektronensystems aromatischer Kohlen-wasserstoffe werden mit denen des Hückel sehen Näherungsverfahrens verglichen. Bei den 18 Molekülen, die zum Vergleich herangezogen werden konnten, ergab sich sehr gute Übereinstimmung.
Wäßrige Sephadex-Gele nehmen Vielfache der in Wasser gelösten Anteile polycyclischer, aromatischer Kohlenwasserstoffe auf, wenn diese als Suspension vorliegen. Beobachtbar ist dieser Effekt an der Erhöhung der Fluoreszenzintensität des gelösten Anteils der Aromaten bei Zugabe von Sephadex-Körnern und anschließender kräftiger Rührung. Verwertbar ist dieses Phänomen zumindest für die Ermittlung der Lage der Emissionsbanden der Kohlenwasserstoffe in Wasser, denn es bestehen nur geringe Unterschiede zwischen den Fluoreszenzsprektren in Sephadex und Wasser. Weiterhin ist beachtlich, daß die carcinogenen Kohlenwasserstoffe nach diesen ersten orientierenden Versuchen, zu einer Gruppe gehören, die eine geringe Diffusionsgeschwindigkeit in das Sephadex-Gel, bei gleichzeitigem Erreichen relativ hoher Endkonzentrationen, besitzen. Der Quotient aus beiden Größen wird daher für die Carcinogene maximal. Nach Desoxycholsäure, Detergentien, Purinen, Desoxynucleinsäuren, Adenosintriphosphat 24 und Proteinen wurde damit gefunden, daß auch Polysaccharid-artige Systeme in der Lage sind, Lösungs-vermittelnd auf Kohlenwasserstoffe in wäßriger Phase zu wirken.
Es verspricht daher, interessant zu werden, an Sephadex, als primitivem Modell von Zellbestandteilen, in der Zukunft standartisierte Kohlenwasserstoff-Suspensionen in dieser Weise zu untersuchen und gleiche Experimente mit stärker hydrophobiertem Gel durchzuführen.
In wäßrig gepufferten Mitochondrien-Suspensionen konnte ein selektives Lösungsvermögen für carcinogene Kohlenwasserstoffe mit Hilfe fluoreszenz-spektroskopischer Messungen festgestellt werden. Gleichzeitig wird eine starke Verminderung der Atmung der Mitochondrien durch die Einwirkung der gelösten, polycyclischen Aromaten beobachtet. Nicht carcinogene Kohlenwasserstoffe werden weder gelöst, noch zeigen sie einen Einfluß auf die Atmung. Sehr schwer lösliche Carcinogene und schwächer wirksame Kohlenwasserstoffe werden in den angewandten Versuchszeiten weder gelöst, noch vermindern sie die Geschwindigkeit des Sauerstoffverbrauchs.
Mitochondrien älterer, oder mit Vitamin B2-Mangel behafteter Tiere zeigen erhöhte Depression der Atmung bei Zugabe von DMBA bzw. 3.4-Benzpyren.
Es wird versucht, diese Effekte einer reinen Promotor-Aktivität der polycyclischen, aromatischen Kohlenwasserstoffe zuzuschreiben, die an den Strukturelementen der Zellatmung (Mitochondrien) einsetzt.
Kristallisierte Lactat-Dehydrogenasen aus Schweineherz, Kaninchenskelettmuskel, Rattenherz und Rattenskelettmuskel wurden mit Trypsin abgebaut und die durch Hochspannungs-Elektrophorese der Verdauungsansätze erhaltenen Peptidmuster nach Anfärbung mit Ninhydrin und diazotierter Sulfanilsäure miteinander verglichen. Es ergaben sich die in den Abb. 1-4 dargestellten Unterschiede.
Glycol causes a denaturation of the DNA double helix structure in solution. As could be shown earlier, heat denaturation of DNA leads to an increased dimerization of thymine following uvirradiation. In contrast to this, thymine dimer is not increased - but is even slightly decreased - when DNA is uv-irradiated in the presence of glycol. These results are discussed with regard to the distortion of the hydration layer and the hydrophobic stacking of bases, as influenced by glycol.
Li6UO6 has a reversible phase transformation at 680°C and decomposes above about 850°C. At high pressure the low temperature modification becomes unstable because of an invariant point in the system Li2O—Li4UO5 at approximately 13 Kb and 620°C. β-Li6UO6 has a triclinic unit cell with a = 5.203, b= 5.520, c = 5.536 Å, α = 114.7, β = 120.7 and γ = 75.5°. The close relationship between the crystal structures of Li6TeO6 and Li6UO6 is also suggested from similar infrared spectra and from partial solid solution Li6UO6—Li6TeO6.
Following treatment with the β-galactosidase inducer [methyl-3H] -thiogalactoside, an induceracceptor-complex was isolated from extracts of E. coli K 12 using DEAE cellulose chromatography. Enzymatic digestion with trypsin suggested that the inducer was bound to a protein component.
Specific radioactive peaks demonstrated acceptor activity in the inducible strains E. coli K 12 and ML 3, but different results were obtained using the non-inducible mutants ML 35, ML 308 and ML 309.
The potent inhibitor of TMG-induction, o-nitrophenylfucoside, reduced the radioactive acceptor peak and caused a similar inhibition of β-galactosidase synthesis, p-nitrophenylfucoside was ineffective.
Further evidence is presented for the in vitro formation of an inducer-acceptor-complex in cell free extracts of E. coli K 12.
The trifluoroacetylation of thymidine at room temperature was performed using trifluoroacetic acid phenylester in pyridine. A selective protection of the 5′-position was not possible: Even low molar quantities of the trifluoroacetylating agent gave rise to bis-trifluoroacetylation. The bis-trifluoroacetyl derivatives of thymidine and 5-bromo-deoxyuridine were purified by vacuum sublimation. The completely trifluoroacetylated deoxyribosides of uracil, 5-iodouracil and adenine underwent decomposition during sublimation.
Die Lichtabsorptionseigenschaften einer Reihe von Lösungen der Komplexionen des dreiwertigen Vanadins vom Typus [V A6]3+, wo A H2O, CH3OH, C2H5OH sowie iso-C4H9OH ist, wurden gemessen. Ferner wurden die Absorptionsspektren von kristallisiertem Ammonium-sowie Caesiumvanadin(III)-alaun aufgenommen.
Intensitätsverhältnisse und spektrale Lage der in allen Spektren auftretenden langwelligen Banden stehen in guter Übereinstimmung mit den Aussagen der Theorie für den Fall eines Zentralions mit zwei d-Elektronen bei Oh-Symmetrie des Komplexfeldes.
Es wurden mehrere unkonjugierte 2.4-Diaminopteridine erstmals synthetisiert. Die Wachstumshemmung verschiedener Mikroorganismen durch 2.4-Diamino-6-[1.2-dihydroxypropyl-(ʟ-erythro)] pteridin (Aminobiopterin) und anderer unkonjugierter 2.4-Diamino-pteridine läßt sich nur mit Folsäure oder Thymin, nicht dagegen mit Biopterin aufheben.
Die Ergebnisse quantentheoretischer Modellrechnungen zur Deutung der von WALDEN sowie von STRAUSS und DÜTZMANN beobachteten elektrolytischen Dissoziation organischer Chlorverbindungen in flüssigem SO2 werden mitgeteilt. Anschließend werden die Ergebnisse von Leitfähigkeitsmessungen an Tritylchlorid in SO2-Lösung dargestellt.
In order to determine the influence of OH and O2H-radicals on proteins, bovine serum albumin (BSA) in aqueous solution was treated with Fenton’s reagent [Fe(II)SO4+EDTA+H2O2] and with ultraviolet light (λ > 2800 Å) in the presence of H2O2. The action of free radicals produced in this way did not change the properties of the native protein with respect to the sedimentation in the ultracentrifuge or optical rotatory dispersion and electrophoresis under normal conditions. Ampèrometric titration indicated partial oxidation of SH-groups and of 3—5 SS-groups which are not reducible by NaBH4.
Heat aggregation investigated by means of light-scattering was suppressed at pH 7.5 and strongly accelerated at pH 4.6 (range of coagulation), the latter being a result of increased entropy of activation of coagulation velocity.
The difference spectrum against native BSA had positive values of Δε and two maxima at 2480 and 2950 Å.
Ultracentrifugation at room temperature in phosphate buffer (pH 7.3, μ=0.18) furnishes a molecular weight of 63 300. In a solution of 8 M urea and borate buffer (pH 9, μ=0.05) fragments with molecular weights between 25 000 and 37 000 were observed while in phosphate buffer (pH 7.3, without urea) at temperatures higher than 46 °C an anomalous behaviour of the concentration gradient indicated an effect which possibly depends on a dissociation equilibrium.
As a consequence oxygen radicals seem to attack not only SH- and SS-groups but at least one covalent bond of the peptide chain. Some experiments of heat aggregation with BSA treated with γ-rays (60Co) gave the same results as BSA treated with Fenton’s reagent or UV-light+H2O2.
S4N3Cl reacts with sulfonic acids and imido- bissulfonyl derivatives under HCl-evolution to the following compounds: S4N3SO3CF3, S4N3N (SO2F)2, S4NSO3CH3HSO3CH3, S4N3N (SO2CF3) SO2Cl and S4N3N (SO2CF3) SO2F, They are yellow solids which decompose when heated below the melting point. The compounds are formed in nearly quantitative yield and have been characterized by elemental analysis, nmr and electronic spectra.
Es wird gezeigt, daß man die langwelligen Absorptionsspektren der magnetisch normalen oktaedrischen Komplexionen mit den Übergangsmetallionen Ti3+, V3+, Cr3+, Mn3+ und Fe3+ verstehen kann, wenn man annimmt, daß die schwachen langwelligen Banden durch Übergänge zwischen den Aufspaltungsprodukten der jeweiligen Grundterme entstehen, wobei die Auf-spaltungen durch das elektrostatische Feld der Liganden zustande kommen.
A nucleoprotein of a vitrous consistency was extracted from the gonads of the coalfish (Gadus virens).
The preparation of deoxyribonucleic acid (DNA) from this nucleoprotein and from staphylococci is described. Both of these different kinds of DNA have been mixed with bovine serum albumin or cytochrom c respectively to produce solutions which subsequently were spread onto the Langmuir trough under defined conditions.
After transfer of aliquots from the surface monolayers to carbon support films the preparations were examined with the electron microscope. The micrographs show threads of various lengths, partly stretched, partly folded in loops, consisting of DNA molecules embedded in a protein envelope.
Measurements and calculations of 5900 particles of the complex of Gadus virens-DNA-Albumin, with relatively short threads show a distribution of discontinuous character. If length is plotted against number then it occurs that there are maxima of different lengths of threads. The abscissae of these maxima obey the ratio 1 : 2 : 4 : 8. This holds for longer threads too the maxima of which, however, have smaller ordinate values.
Über den Einfluß der Kationen auf die Kraftkonstanten der WO-Bindung in den Hexaoxowolframaten (VI)
(1970)
Über das Verhalten von silicium- und zinnorganischen Verbindungen bei der Synthese von Heterocyclen
(1977)
The isocyanates of silicon (CH3)2Si(NCO)2 and Si(NCO)4 react with CH3N[Sn(CH3)3]2 and N[Sn(CH3)3]3 to yield the cyclic derivatives 2a-2b as well as the spiro compound 3. The structures of the compounds are discussed on the basis of 1H NMR and IR data. Mass spectra are not conclusive for assigning a certain structure. SO2(NCO)2 and (CH3)3Si-S-Si(CH3)3 form a cyclic compound 4 which contains two sulfur atoms of coordination number two and four. The results of the mass spectra can be interpreted by assuming that a rearrangement occurred. 4 hydrolyses under formation of 5.
Über das dielektrische Verhalten des Diphenyläthers in Mischungen mit unpolaren Flüssigkeiten
(1949)
The reactions of N,N′ -bis(pentafluorophenyl)sulfurdiimide with [(CH3)3Sn]2NCH3, [(CH3)3Sn]3N and [(CH3)3Sn]2NC6F5 yiels the 1:1 adducts 1-3. 1H and 19 F NMR investigations show, that fluorine atoms in the ortho position of the phenyl ring coordinate to the tin atom. This causes an increase of electron density at tin. A similar interpretation is given for the adduct 4 of N,N′-bis(p-chlorophenylsulfonyl)sulfurdiimide and [(CH3)3Sn]2NCH3, where an oxygen atom of the sulfonyl group is bonded to tin.
Mit Hilfe der quantenmechanischen Theorie der aromatischen Verbindungen wird gezeigt, daß aus den neuen experimentellen Befunden von Gillet über die Addition von Maleinsäureanhydrid an 9.10-Diphenyl-anthracen und 9-Phenylanthracen auf eine Verdrehung der Phenylringe gegen das Anthracenskelett geschlossen werden kann.
Im Zuge der steigenden Bedeutung der Proteomforschung und der »Molekularisierung« der Medizin werden neue, effizientere Plattformen zur Untersuchung von Proteinen und deren Wechselwirkungen notwendig. Hier bietet die Nanotechnologie, eine Wissenschaft mit Ursprüngen in der Physik und der Halbleiterindustrie, attraktive Lösungsperspektiven. Ein Bereich der Forschung am Institut für Biochemie der Universität Frankfurt um Prof. Dr. Robert Tampé widmet sich den Aspekten der Nanotechnologie zur Entwicklung von Protein-Chips für die Proteomforschung und Erzeugung von Mustern im Kleinstformat.
The IR-spectra of BaCO3 (80% 13CO32-, 90% 13CO32-) shows small bands in the ν2-region, which are assigned to short waves of 12CO32--chains with three, five or six carbonate ions.
A theory of the luminescence lifetime of a radiation-damped classical electrical point dipole near a plane interface to a medium with different optical constants is given. The influence of the interface on the lifetime of the dipole is calculated in first approximation with the methods of molecular optics. Theoretical and experimental results for a purely dielectric interface are compared.
Das Hückelsche zweite Näherungsverfahren wird durch Mitberücksichtigung der höheren Atomzustände erweitert. Dabei ergibt sich die Erklärung für das Scheibesche Phänomen. Der Begriff „theoretische Sonderenergie (Resonanzenergie)“ wird richtiggestellt. Die bekannten Schwierigkeiten, die sich beim Vergleich spektroskopischer und kalorischer Energiewerte im Rahmen der Einelektronentheorie der π-Elektronensysteme bisher immer ergeben haben, verschwinden.
Resultate der quantenmechanischen Theorie der aromatischen Kohlenwasserstoffe werden mit experimentellen Daten über Anlagerungs-und Umlagerungsreaktionen von aromatischen Systemen verglichen. Zum Vergleich mit der Theorie werden heran-gezogen-, 1. Die Hydrierung aromatischer Kohlenwasserstoffe, 2. die Anlagerung von Maleinsäureanhydrid an aromatische Kohlenwasserstoffe, 3. die Redoxpotentiale der Chinone, 4. die Anthron-Anthranol-Umlagerung. Es zeigt sich, daß die Theorie geeignet ist, den qualitativen Zusammenhang eines großen empirischen Materials befriedigend darzustellen.