Refine
Year of publication
Document Type
- Article (1108)
- Book (639)
- Part of a Book (421)
- Part of Periodical (133)
- Report (94)
- Preprint (82)
- Conference Proceeding (71)
- Other (59)
- Review (57)
- Working Paper (46)
Language
Has Fulltext
- yes (2738) (remove)
Keywords
- Mosambik (121)
- Mozambique (121)
- Moçambique (120)
- Rezension (87)
- Bibel (66)
- Christentum (63)
- bible (63)
- christianity (63)
- Literatur (57)
- Aufsatzsammlung (54)
Institute
- Extern (2738) (remove)
I add new collection and phenological data on the North American earwigfly, Merope tuber Newman, and new county records for the red scorpionfly, Panorpa rufa Gray, and veined scorpionfly, Panorpa venosa Westwood, in Florida. Additionally, I report on a new Georgia county record for the extralimital species, Panorpa ferruginea Byers, the ferruginous scorpionfly, and speculate on its potential occurrence in Florida.
In 1947, 20 species of Staphylinidae were reported from the Cayman Islands as a result of an Oxford University expedition there in 1938 which made extensive use of a light trap. The list is here expanded to 62 species based on collections by R. R. Askew, G. E. Ball, E. A. Dilbert, B. K. Dozier, E. J. Gerberg, P. J. Fitzgerald, M. C. Thomas, and R. H. Turnbow since 1970, all of whom also used light traps except for a collection or two by flight intercept trap.
Neoma, a new genus of Cerambycidae (Coleoptera: Cerambycidae: Prioninae: Macrotomini) is described for Mallodonopsis corrosus Bates, 1879, compared to related genera (Aplagiognathus Thomson, 1861; Archodontes Lameere, 1903; and Mallodonopsis Thomson, 1861), and its tribal position discussed. A lectotype for Mallodonopsis corrosus is here designated with the species redescribed and figured.
The monotypic aesaline genus Lucanobium Howden and Lawrence (Coleoptera: Lucanidae) was previously known only from Venezuela. A second species is here described as new from French Guiana, extending the range of the genus approximately 1800 km to the southeast. The generic description of Lucanobium is updated with respect to the discovery of a second species.
Studierende und Lehrende des Faches Allgemeine und Vergleichende Literaturwissenschaft, die in den Beständen ihrer Bibliothek nicht fündig geworden sind, werden sich vielleicht fragen, warum viele ihrer Fernleihen von der Universitätsbibliothek Frankfurt am Main stammen. Dass sich ausgerechnet dort das Sondersammelgebiet für Allgemeine und Vergleichende Literaturwissenschaft befindet, mag überraschen, denn schließlich wurde an der Goethe-Universität ein eigenes Institut für Komparatistik erst im Sommersemester 2001 gegründet. [...] Die bedeutenden Bestände der Rothschildschen Bibliothek, die durch rechtzeitige Auslagerung ohne größere Verluste den Zweiten Weltkrieg überstanden haben, waren u. a. ausschlaggebend dafür, dass 1949 der damaligen Stadt- und Universitätsbibliothek Frankfurt von der Deutschen Forschungsgemeinschaft die Sondersammelgebiete »Allgemeine und Vergleichende Sprachwissenschaft« (SSG 7.11), »Germanistik« (SSG 7.20) sowie »Allgemeine und Vergleichende Literaturwissenschaft« (SSG 7.12) zugewiesen wurden. [...] So sehr es auch Utopie bleiben wird, gerade im Blick auf eine per se fachübergreifende Disziplin, so besteht doch der Anspruch, die wissenschaftliche Literatur eines Faches (auch und gerade die im Ausland erscheinende) möglichst umfassend und vollständig zu sammeln […]. Publikationen in digitaler Form sind solchen in konventioneller Gestalt gleichgestellt. Jede wissenschaftliche Publikation ist damit im Idealfall zumindest einmal in Deutschland vorhanden.
Der Übersetzungsprozess der Technischen Dokumentation wird zunehmend mit Maschineller Übersetzung (MÜ) unterstützt. Wir blicken zunächst auf die Ausgangstexte und erstellen automatisch prüfbare Regeln, mit denen diese Texte so editiert werden können, dass sie optimale Ergebnisse in der MÜ liefern. Diese Regeln basieren auf Forschungsergebnissen zur Übersetzbarkeit, auf Forschungsergebnissen zu Translation Mismatches in der MÜ und auf Experimenten.
Standardisierung ist der bedeutendste Ansatz zu Qualitätssteigerung und Kostensenkung in der Technischen Dokumentation. Es gibt eine Reihe von Standardisierungsansätzen: Modularisierung, Informationsstrukturen, Terminologie, Sprachstrukturen. Dennoch werden diese Ebenen meist getrennt voneinander beschrieben. Wir untersuchen, wie Standardisierungen im Informationsmodell, in der Terminologie und in den sprachlichen Strukturen verknüpft werden und miteinander interagieren.
Cephaloleia consanguinea Baly, Cephaloleia fulvolimbata Baly, Cephaloleia ruficollis Baly, Chalepus amabilis Baly, Chalepus brevicornis (Baly), Chalepus pici Descarpentries and Villiers, Microrhopala erebus (Newman), Octhispa bimaculata Uhmann, Octotoma championi Baly, Pseudispa tuberculata Staines, Sceloenopla erudita (Baly), Stenispa guatemalensis Uhmann, Sumitrosis gestroi (Weise), and Sumitrosis terminatus (Baly) (Coleoptera: Chrysomelidae: Cassidinae) are new country records of hispine chrysomelids for Belize, based on collections cited herein. These collections also document new host records for Calyptocephala gerstaeckeri Boheman (Chamaedorea tepejilote Liebm., Arecaceae), Cephaloleia consanguinea (Heliconia bourgaeana Petersen, H. collinsiana Griggs, H. latispatha Benth., H. wagneriana Petersen; Heliconiaceae), and Cephaloleia perplexa Baly (Heliconia bourgaeana, H. latispatha; Heliconiaceae).
El objetivo de este trabajo fue determinar las especies de cocoideos (Hemiptera: Sternorrhyncha: Coccoidea) presentes en Sierra del Rosario y Sierra de los Órganos, Cordillera de Guaniguanico, provincia de Pinar del Río; así como, obtener la relación de sus plantas hospedantes. Se revisaron las Colecciones Zoológicas del Instituto de Ecología y Sistemática (CZACC), Cuba, las publicaciones cubanas sobre cocoideos y ScaleNet, que es una base de datos de los cocoideos del mundo. Se realizó una representación cartográfica de las localidades de recolección sobre un mapa a escala de 1:250000, utilizando el programa MapInfo Professional Versión 4.5. Se hallaron 53 especies de cocoideos, agrupados en 42 géneros y seis familias, de las cuales 11 especies se registraron por primera vez para el área de estudio: Coccus longulus (Douglas, 1887), Kilifia acuminata (Signoret, 1873), Parasaissetia nigra (Nietner, 1861), Protopulvinaria pyriformis (Cockerell, 1894), Pseudokermes vitreus (Cockerell, 1894), Aspidiella sacchari (Cockerell, 1893), Duplaspidiotus tesseratus (Grandpré & Charmoy, 1899), Pinnaspis aspidistrae (Signoret, 1869), Pinnaspis strachani (Cooley, 1899), Pseudoparlatoria parlatorioides (Comstock, 1883), y Eriococcus sp. Se relacionaron 54 especies de cocoideos y 36 familias de plantas hospedantes con nuevos registros de éstas. Palabras clave. Coccoidea, Sternorrhyncha, Hemiptera, plantas hospedantes, nuevos registros, Cuba.
Neolecanium amazonensis Foldi is redescribed and illustrated and is transferred to the new genus Foldilecanium Kondo as Foldilecanium amazonensis (Foldi) comb. nov. A new species, Foldilecanium multisetosus Kondo, is described and illustrated based on specimens collected in Cali, Colombia, on Cananga odorata (Lam.) Hook.f. and Thomson (Annonaceae). An updated taxonomic key to New World Myzolecaniinae and a key to separate the two species of Foldilecanium are provided.
Background: The treatment of high-risk neuroblastoma patients consists of multimodal induction therapy to achieve remission followed by consolidation therapy to prevent relapses. However, the type of consolidation therapy is still discussed controversial. We applied metronomic chemotherapy in the prospective NB90 trial and monoclonal anti-GD2-antibody (MAB) ch14.18 in the NB97 trial. Here, we present the long term outcome data of the patient cohort. Methods: A total of 334 stage 4 neuroblastoma patients one year or older were included. All patients successfully completed the induction therapy. In the NB90 trial, 99 patients received at least one cycle of the oral maintenance chemotherapy (NB90 MT, 12 alternating cycles of oral melphalan/etoposide and vincristine/cyclophosphamide). In the NB97 trial, 166 patients commenced the MAB ch14.18 consolidation therapy (six cycles over 12 months). Patients who received no maintenance therapy according to the NB90 protocol or by refusal in NB97 (n = 69) served as controls. Results: The median observation time was 11.11 years. The nine-year event-free survival rates were 41 ± 4%, 31 ± 5%, and 32 ± 6% for MAB ch14.18, NB90 MT, and no consolidation, respectively (p = 0.098). In contrast to earlier reports, MAB ch14.18 treatment improved the long-term outcome compared to no additional therapy (p = 0.038). The overall survival was better in the MAB ch14.18-treated group (9-y-OS 46 ± 4%) compared to NB90 MT (34 ± 5%, p = 0.026) and to no consolidation (35 ± 6%, p = 0.019). Multivariable Cox regression analysis revealed ch14.18 consolidation to improve outcome compared to no consolidation, however, no difference between NB90 MT and MAB ch14.18-treated patients was found. Conclusions: Follow-up analysis of the patient cohort indicated that immunotherapy with MAB ch14.18 may prevent late relapses. Finally, metronomic oral maintenance chemotherapy also appeared effective.
A catalogue of aphidiine parasitoids (Hymenoptera: Braconidae: Aphidiinae) associated with various aphids species occurring in India was compiled. The present catalogue with 125 species under 22 genera has been further reinforced with not only all the latest taxonomic changes but also host names, host plants, distribution in India etc.
Ein Dorfrichter missbraucht seine Amtsautorität, nötigt eine junge Frau sexuell, indem er ihr droht, dafür zu sorgen, dass ihr Verlobter als Soldat in einem Kolonialkrieg verheizt wird, sollte sie ihm nicht zu Willen sein. Bei seiner […] Flucht vom Tatort zerschlägt er einen Krug. Dieser […] bezeichnet die mutmaßlich geraubte Unschuld der jungen Frau. Sex and Crime also – von Kleist indes als Komödie präsentiert. Angesichts der körperlichen Schändung […] erscheint diese Gattungsentscheidung gewagt; zumal Kleists Darstellung auf den ersten Blick keine allzu große Empathie für die geschädigte Seite dokumentiert. Wie so oft bleibt nämlich die Paraderolle dem Bösewicht vorbehalten: dem Dorfrichter Adam. Frau Marthe Rull hingegen, die Mutter des vergewaltigten Mädchens und Eigentümerin des zerbrochnen Krugs, gilt nicht gerade als Sympathieträgerin […]. Ihre insistierende Klage vor Gericht, in der sie den Krug mit aller Einlässlichkeit beschreibt, weist sie in den Augen der amerikanischen Kleistexpertin Ilse Graham als überaus »schlichte Person« aus, ja lässt sie gar zu einem Musterbeispiel »törichter Besessenheit« werden. Man kann solchen Furor gegenüber einer literarischen Figur befremdlich finden, Fakt ist allerdings, dass Frau Marthe auch für den heutigen Theaterzuschauer zunächst einmal eine Nervensäge ist. Ihre langatmige Beschreibung des Krugs bringt den sonst besonnenen Gerichtsrat Walter dazu, sie ein ums andere Mal mit Einwürfen wie »weiter, weiter« zu mehr Stringenz anzutreiben.
Deutsch im Kreis Schanfigg
(2012)
In dieser Arbeit wird unter Schanfigg nach Kessler "Schanfigg im weitern Sinne" verstanden, d.h. die Dörfer des politischen Kreises Schanfigg [...]. Da Dialekte im Gegensatz zu Hochsprachen nicht-normierte Sprachvarietäten darstellen, zeichnen sich die Ortsgrammatiken durch eine jeweils enorme Formenvielfalt in lautlicher und in morphologischer Hinsicht aus. Dies war denn auch eines der Ziele der Untersuchung: Mit Hilfe der Prager Phonologie und der auf ihr beruhenden Morphologie sollte aufgezeigt werden, wie groß die allophonische und allomorphische Bandbreite ist, derer sich die Sprecher im Gespräch unbewußt bedienen. Sehr schön läßt sich dies anhand der Verbalmorphologie bei den unregelmäßigen Verben (Kurzverben) aufzeigen. Ein weiteres Ziel der Untersuchung war es, die Stellung der Ortsdialekte des Schanfiggs und ihres Gesamts, also das Schanfigger Diasystem, innerhalb der dem Schanfigg benachbarten Mundarten darzustellen. Idealerweise hätten das Prättigau, das Churwaldner Tal und die Churer bzw. Churerrheintaler Mundarten herangezogen werden müssen. Da aber leider keine Untersuchungen zu den Verhältnissen im Prättigau und im Churwaldner Tal vorhanden sind, wurden die Schanfigger Verhältnisse mit denjenigen der Stadt Chur (vgl. Eckhardt 1991) und des Deutschen im Bezirk Imboden (vgl. Toth und Ebneter 1996) verglichen.
Eine der primären Aufgaben nicht nur der Komparatistik, sondern der Literaturwissenschaft im Allgemeinen sollte es sein, Literatur als ein globales Phänomen zu erfassen und zu beschreiben. Manifestiert sich der globale Charakter von Literatur auch am augenscheinlichsten im Rahmen einer Poetik der imitatio in motivischer, thematischer und gattungsgeschichtlicher Hinsicht, so besteht er dennoch auch dann, wenn bestimmte Techniken eine internationale Präsenz besitzen. Dies gilt beispielsweise für die Konkrete Poesie, deren Funktion als einer der Katalysatoren der Globalität von Literatur im Folgenden erläutert wird.
Konkrete Poesie ist per se ein internationales Phänomen, oder wie Eugen Gomringer es formuliert hat: „die konkrete poesie […] ist einer der konsequentesten versuche, poesie inter- und übernational zu begründen.“ Zunächst müssen wir – im Sinne wissenschaftlicher Eindeutigkeit – zwischen einem engeren und einem weiteren Begriff der Konkreten Poesie unterscheiden. Die Konkrete Poesie im engeren Sinne meint eine seit den 1970er Jahren historisch gewordene Dichtung. Ihre ‘Geburtsstunde’ lässt sich zu Recht als „transatlantic baptism“ , nämlich durch Eugen Gomringer und Décio Pignatari in der Hochschule für Gestaltung im Jahre 1955 in Ulm, bezeichnen. In den frühen 1950er Jahren sowohl in Deutschland als auch Brasilien entstanden, findet sie Aufnahme in fast allen europäischen Ländern, Nordamerika und Japan. Im Folgenden soll der Begriff der Konkreten Poesie jedoch nicht in diesem unnötig eingeschränkten historischen Sinn gebraucht werden, sondern in einem sehr viel umfassenderen Sinn: Er ist all jenen Gedichten vorbehalten, in denen eine Transpa-renz des Zeichengebrauchs nicht gegeben ist, sondern stattdessen die Materialität der jeweils eingesetzten Zeichen im Vordergrund steht, wie dies auf ähnliche Weise schon im Futurismus und Dadaismus betrieben wurde, bevor der Surrealismus diesen Experimenten ein jähes Ende bereitet hat. Gilt dies auch für die Bereiche der Lautdichtung, der Gedichtobjekte u. ä., so beschränken sich die folgenden Ausführungen auf den visuellen Bereich, und zwar auf visuelle Konkrete Poesie nach 1945, zumal in der Dichtung aus dieser Zeit eine starke Tendenz zu konkretistischen Verfahrensweisen herrscht.
Aufgabe dieser Magisterarbeit ist die digitale Visualisierung von literarischen Strukturen digitalisierter Literatur. Textgrundlage bilden ausgewählte Loreley-Gedichte. Nach einer theoretischen Einordnung dieser Arbeit sowie zweier Digitalisierungsprojekte der Literaturwissenschaft (Heinrich-Heine-Portal und Projekt Loreley) sollen im Hauptteil die Möglichkeiten einer grafischen Illustration mit digitalen Mitteln formaler und semantischer Strukturen erörtert und exemplarisch demonstriert werden. Als Auszeichnungssprache zur digitalen Erfassung sowie zur Kodierung der Interpretationen wird die XML-Applikation TEI-Lite verwendet. Die Visualisierung erfolgt mittels XSLT als XHTML und SVG.
Recent fieldwork on North Andros Island by the authors resulted in the collection of six species of Pterophoridae
(Lepidoptera), five of which were previously unrecorded for the Bahamas in published accounts. Three
additional species are noted for the Bahamian fauna based on specimens collected in the 1980s on other islands.
Representative specimens are illustrated from North Andros along with genitalic images for species where these
are not readily available in other publications. In addition, images of the larva and pupa are provided for a reared
species for which the life history was previously unknown.
Snoqualmia, new genus, is described for two species of polydesmid millipeds from the northwestern
United States: Snoqualmia snoqualmie, new species, from Washington State, and S. idaho, new species,
from Idaho. Males of S. idaho possess unusually complex gonopods, perhaps the most complex to be found in the Order
Polydesmida. Snoqualmia is placed in context with other polydesmid genera known from North America. The
polydesmid fauna of North America is discussed, as well as characters of the gonopods of the family.
Studia Austriaca ; 13.2005
(2012)
Grazie all’accordo concluso con il Console Mario Erschen nel 1994, e rinnovato con la Dr. Stella Avallone nel 2003, anche questo nuovo volume di Studia austriaca esce per iniziativa congiunta del Forum Austriaco di Cultura (già Istituto Austriaco di Cultura) a Milano e della Sezione di Germanistica (già Istituto di Germanistica) del Dipartimento di Studi Linguistici, Letterari e Filologici (DI.LI.LE.FI) dell’Università degli Studi di Milano.
La Reserva de la Biosfera de Chamela-Cuixmala se localiza en la costa del Pacífico del estado mexicano de Jalisco. La Reserva fue fundada en 1993 y se extiende por 13142 hectáreas. Es una de las pocas reservas en México creada para la protección de la selva tropical caducifolia (seca) y sistemas asociados. Cinco especies de ciempiés han sido registradas previamente para la Reserva: Cormocephalus impressus Porat, 1876; Dendrothereua linceci (Wood, 1867); Ectonocryptoides quadrimeropus Shelley y Mercurio, 2005; Scolopendra polymorpha (Wood, 1861) y Scolopendra viridis Say, 1821. A partir de julio de 2010 se inició con el primer estudio formal de la fauna de ciempiés en la Reserva. Después de un año de muestreos, ocho morfoespecies de ciempiés se han determinado para la Reserva: Cryptops (Haplocryptops) cf. acapulcensis Verhoeff, 1934; Cryptops sp.; Rhysida immarginata (Porat, 1876); Scolopendra morsitans Linnaeus, 1758; Polycricus sp.; Sogona sp.; Orphnaeus sp.; y Straberax sp. Esta es la primera vez que Cryptops (Haplocryptops) cf. acapulcensis es encontrada en otra localidad distinta de su localidad tipo. Estudios previos han determinado el papel de los ciempiés como parte de la dieta de mamíferos y componente de la fauna del suelo.
The taxonomic position of Onthophagus (Palaeonthophagus) lemuroides d’Orbigny, 1898 and Onthophagus
(Palaeonthophagus) fortigibber Reitter, 1909 is discussed (Coleoptera: Scarabaeidae: Scarabaeinae: Onthophagini).
A key to the species is given. Photos of type specimens of the two taxa and significant chromatic varieties, and
drawings of aedeagi are presented.
Extreme economic effects globally of various populations of the whitefly Bemisia tabaci (Gennadius)
(Hemiptera: Aleyrodidae) led to an in depth study of the morphology of that species as well as that of
numerous other species of whiteflies in the genus Bemisia Quaintance and Baker and other similar appearing
species. The data collected are presented here as illustrations of the puparia (fourth instar nymphal stages)
and discussions of morphology as it relates to species and generic separations within this closely knit group
of insects. A brief history of the pest outbreaks of B. tabaci is given and an overview of the important
morphological characteristics of aleyrodine whiteflies is provided. Each of the eighty illustrations is
accompanied by a discussion of the more important aspects of morphology.
A taxonomic review of the ancora species group of Graphipterus Latreille (Coleoptera: Carabidae)
(2012)
The taxonomy of the ancora species group of Graphipterus Latreille (Coleoptera: Carabidae) is reviewed and seven species are recognized, all from southern Africa: Graphipterus ancora Dejean, Graphipterus cordiger Dejean, Graphipterus distinctus Péringuey (new status), Graphipterus fasciatus Chaudoir, Graphipterus fritschi Chaudoir, Graphipterus wahlbergi Boheman (new status), and Graphipterus westwoodi Brême (new status).
Diagnostic features are provided for each species and adult specimens of each species are illustrated.
Two new species of the genus Pahamunaya Schmid (Trichoptera: Polycentropodidae), P. talon sp. n. and P. spinifera sp. n., from Vietnam are described and illustrated. Examination of the holotype male of P. khoii Oláh and Johanson, in combination with an additional specimen of the same species, revealed new characters. New illustrations for this species are provided.
Significant new host and distribution records are presented for Hylesinus mexicanus (Wood) (Coleoptera: Curculionidae: Scolytinae), including its pest potential on cultivated olives. Hylesinus mexicanus is similar to H. fasciatus LeConte and information presented here suggests that the distinctiveness of these two species needs to be re-examined.
Currently, the genus Chimarra Stephens (Trichoptera: Philopotamidae) is represented in the Oriental Region by 259 species. Of these, 61 species have been described or recorded from Vietnam. In this paper, 9 new species from Vietnam are described and illustrated (Chimarra aculeata, C. carinata, C. corneola, C. insolita, C. mina, C. prominens, C. rostrata, C. undulata, and C. ungula). In addition, 3 new country records are noted (Chimarra areli Malicky and Mey, Chimarra pipake Malicky and Chantaramongkol, and Chimarra suthepensis Chantaramongkol and Malicky), and 1 new species group (minuta Group) is proposed and populated. An additional species group (georgensis “Group”), with 1 new species from Vietnam, but otherwise only known from Africa, is discussed, but not formally defined. A table listing all known Vietnamese species of Chimarra is included, along with discussion of variability in the anal veins of the forewing found within this genus, and its relevance for defining subgenera and species groups.
The diplopod orders Callipodida and Polydesmida, and their respective families Abacionidae and
Xystodesmidae, are initially recorded from South Dakota as is Polydesmidae from North Dakota. Other new records of
indigenous taxa include Abacion Rafinesque, 1820/A. texense (Loomis, 1937) and Pleuroloma/P. flavipes, both by
Rafinesque, 1820, from South Dakota, and Pseudopolydesmus Attems, 1898/P. serratus (Say, 1821) from Alabama,
Connecticut, Delaware, New Hampshire, North Dakota, South Carolina, and the District of Columbia. New records of
Aniulus garius Chamberlin, 1912, A. (Hakiulus) d. diversifrons (Wood, 1867), and Oriulus venustus (Wood, 1864)
(Julida: Parajulidae) are provided for western Minnesota and/or eastern North Dakota. Published records from these
states are summarized, and the introduced taxa, Julidae/Cylindroiulus Verhoeff, 1894/C. caeruleocinctus (Wood, 1864)
and Paradoxosomatidae/Oxidus Cook, 1911/O. gracilis (C. L. Koch, 1847), are newly recorded from the Dakotas. The
distribution of P. serratus, which extends from Maine to South Carolina and the Florida panhandle, west to Texas, and
north to Fargo, North Dakota is described and discussed. This distribution exhibits a prominent southeastern lacuna
which we hypothesize suggests replacement by younger, more successful species, as postulated for a similar distributional
gap in Scytonotus granulatus (Say, 1821).
The milliped genus Euryurus Koch, 1847, and the species, E. leachii (Gray, 1832) (Polydesmida: Euryuridae), are recorded from three sites on the northern part of Crowley’s Ridge (Cross, Lee, and Poinsett counties), Arkansas, where the only prior familial records are of Auturus evides (Bollman, 1887). Coupled with the published locality of E. leachii in Phillips Co., at the southern extremity of the Ridge, the only known occurrences of both the genus and species in Arkansas and west of the Mississippi River are in this physiographic feature. The Arkansas population is geographically peripheral but anatomically intermediate between the two recognized subspecies, E. l. leachii and E. l. fraternus Hoffman, 1978, and we do not assign it to a race. Molecular investigations seem necessary to resolve relationships in the “E. leachii complex.”
With the discovery of Mitocybe auriportae Cook and Loomis, 1928 (Platydesmida: Andrognathidae) in Alameda County (Co.), east of San Francisco Bay, a potential overall distribution in coastal California is projected based on those of partly congruent diplopods. The area extends from northern Mendocino to central Monterey cos. and inland to central Lake, Yolo, and Santa Clara cos.
Evidence is presented that the subspecies Chrysobothris thoracica guadeloupensis Descarpentries, 1981
(Coleoptera: Buprestidae) should be recognized at the species level. Character evidence is provided to separate C.
guadeloupensis, new status, from C. thoracica Fabricius, 1798. Both species are illustrated with habitus photographs
and images of the male genitalia.
Die "Jedermann-Lizenzen" von Creative Commons (CC) geben Menschen die Möglichkeit, ihre kreativen Werke unter bestimmten Bedingungen zur Nutzung freizugeben. Weil Urheber unterschiedliche Motive und Interessen haben, gibt es sechs verschiedene Lizenzvarianten. Die beliebteste ist die Einschränkung, dass Werke nur nicht-kommerziell verwendet werden können. Das hat aber weitreichende Folgen für die Verbreitung der Inhalte. Gleichzeitig erreichen viele Creative-Commons-Nutzer dadurch gar nicht die gewünschten Ziele. Diese Broschüre informiert über Folgen, Risiken und Nebenwirkungen einer Beschränkung der CC-Lizenz auf nicht-kommerzielle Nutzung.
Chalcosicya maya, new species, (Coleoptera: Chrysomelidae: Eumolpinae) is described and the species
key of Blake (1951) is modified to accommodate it. This is the first known mainland species of this previously
Antillean genus. Sclerotized rods in the apical segment of the ovipositor of Chalcosicya Blake and related genera
are shown to be useful systematic characters within the eumolpine tribe Adoxini. Relationships with other genera
suggest that Chalcosicya belongs to a clade derived from ancestors with a western Tethyian distribution.
[D]ieser Veranstaltungstyp [wurde] 1996 etabliert […] und die komparatistisch angelegte Konferenz der Abteilung 2012 [wird] nunmehr zum 17. Mal in Folge ausgerichtet […]. Über den Kreis der 15 Referenten hinaus war sie mit etwa 120 aktiv mitdiskutierenden Teilnehmern gut besucht. Thematisch orientiert sich die Konferenz jeweils an einem Semesterkurs, den die Studierenden der am Department angebotenen Master‐Studiengänge (Deutsch, Französisch, Spanisch, Italienisch) durchlaufen.
During the 1930s through the 1940s and into the 1950s, Spanish and German presentations in opposition to ardent nationalism share strikingly common aesthetic and ideological strategies supporting claims to a transnational, international space. Specific examples of common geography, identity and language in German and Spanish presentations (theater, short stories, reports, essays, speeches and poetry) in Spain and Latin America by German (Regler, Renn, Uhse), Spanish (J. Bergamin, R. Alberti, M. Aub) and Latin American (D. Rivera, P. Neruda, C. Vallejo) intellectuals, artists and activists during the 1930s through the 1950s will be explored. For example, German-speaking audiences and artists in Spain and Mexico shared a common lived and aesthetic space as Spanish-speaking audiences and artists. Further, many German presentations were translated into Spanish and visa versa. Here, presentations in “Das Wort” and “El Mono Azul” in Spain as well as “Freies Deutschland/Alemania libre” in Mexico will be referenced in developing a sense of re-definition of the concept of ‘foreign’ and ‘commonness’ beyond simply nationality (tradition, history and geography) and language. The impetus for an alternative, international and even revolutionary ‘space’ (as defined by Henri Lefebvre in The Production of Space) was produced in and through common Spanish and German strategies and realizations in their presentations. This Spanish-German example from the early/mid-part of the 20th century is a significant contribution to contemporary interdisciplinary discussions in the 21st century.
The Caribbean Islands (or the West Indies) are recognized as one of the leading global biodiversity hot
spots. This is based on data on species, genus, and family diversity for vascular plants and non-marine vertebrates. This
paper presents data on genus level endemicity for the most speciose (but less well publicised) group of terrestrial
animals: the beetles, with 205 genera (in 25 families) now recognized as being endemic (restricted) to the West Indies.
The predominant families with endemic genera are Cerambycidae (41), Chrysomelidae (28), Curculionidae (26), and
Staphylinidae (25). This high level of beetle generic endemicity can be extrapolated to suggest that a total of about
700 genera of all insects could be endemic to the West Indies. This far surpasses the total of 269 endemic genera of all
plants and non-marine vertebrates, and reinforces the biodiversity richness of the insect fauna of the West Indies.
We provide the first records of six species of biting midges (Diptera: Ceratopogonidae) in the genus
Culicoides Latreille from Mexico: C. baueri Hoffman, C. castillae Fox, C. debilipalpis Lutz, C. iriartei Fox, C. leoni
Barbosa and C. pusilloides Wirth and Blanton. In addition, C. leopoldoi Ortiz is confirmed from Mexico, and new
records are included for 25 other species previously recorded in Mexico: C. arubae Fox and Hoffman, C. blantoni Vargas
and Wirth, C. crepuscularis Malloch, C. daedalus Macfie, C. diabolicus Hoffman, C. foxi Ortiz, C. furens (Poey), C.
gabaldoni Ortiz, C. haematopotus Malloch, C. hylas Macfie, C. insignis Lutz, C. jamaicensis Edwards, C. luteovenus
Root and Hoffman, C. neopulicaris Wirth, C. nigrigenus Wirth and Blanton, C. pampoikilus Macfie, C. panamensis
Barbosa, C. paraensis (Goeldi), C. phlebotomus (Williston), C. poikilonotus Macfie, C. pusillus Lutz, C. stigmalis Wirth,
and all three species in the C. (Monoculicoides) variipennis complex, C. variipennis (Coquillett), C. occidentalis Wirth
and Jones, and C. sonorensis Wirth and Jones.
The mirine plant bug Tropidosteptes forestierae, new species (Hemiptera: Miridae) is described from
Collier County, Florida, where it was found causing serious injury to an extensive ornamental hedge of Florida swampprivet, Forestiera segregata (Jacq.) Krug and Urb. (Oleaceae). Adult male and female, fifth instar, and egg are described. Color images of the adults, nymph, egg, and injury; scanning photomicrographs of selected adult structures; and illustrations of male genitalia are provided. A key to help distinguish the 16 species of Tropidosteptes known to occur in the southeastern United States is given.
Among the four oriental genera of the tribe Helluonini, Omphra Dejean (Coleoptera: Carabidae), is unique for its endemism to the Indian subcontinent and aptery. High intraspecies variability in morphological characters and limited diagnostic information makes species differentiation of the genus Omphra a complicated task. The present study provides a description of a new species, Omphra drumonti n. sp. from the Western Ghats, redescriptions and a key to the species of Omphra, details of intraspecies variation, discussion of relationships between taxa and distributional patterns of the genus. Based on the distributional patterns in the Indian subcontinent and flightlessness of the genus, inability to cross the physical barrier of the Ganges–Brahmaputra delta between north and peninsular India is indicated as the reason for its absence in the northeastern Indian subcontinent and endemism to the lower Indian subcontinent.
„Die Lose ähneln sich, die Odysseen“. Dieser Vers Ingeborg Bachmanns aus ihrem Gedicht Von einem Land, einem Fluss und den Seen behauptet, die Irrfahrten und Schicksale der vielen Odysseus-Gestalten seien einander ähnlich. Wenn sich aber die Schicksale und Heimkehrreisen der Umherwandernden ähneln, dann könnten sich auch ihre literarischen Werke ähnlich sein. Ausgehend von dieser Vermutung sollen im folgenden Beitrag zwei große Lyriker des 20. Jahrhunderts gegenübergestellt werden, die sich mit der Frage des Exils und seiner Überwindung beschäftigt haben: die Österreicherin Ingeborg Bachmann und der Iraker Sa'dī Yūsuf. Zwar gehören beide unterschiedlichen Sprachräumen und Literaturtraditionen an. Zugleich sind sie aber aus diesen Räumen ausgebrochen, um neue geografische, sprachliche und gedankliche (W)orte zu erkunden, die keine fest umrissenen Grenzen mehr kennen. Darüber hinaus haben sie in ihren Texten auf ähnliche Weise Untergänge und Auferstehungen inszeniert, die meines Erachtens den Erfahrungen ihres Exils entspringen. Ihre Sichtweisen auf das Eigene und Fremde fordern uns auf, unseren eigenen Blick in einer Zeit zunehmenden und zugleich konfliktreicheren Zusammenlebens zu öffnen und zu hinterfragen.
Around 1800, aesthetic debate suddenly places music at the very top in the hierarchy of the arts, even superseding poetry: This has become a commonplace not only in scholarly discourse. The protagonists of this re-arrangement of the artistic disciplines are Wilhelm Heinrich Wackenroder, E.T.A. Hoffmann and Ludwig Tieck. In their programmatic texts, they state that music is to be free and absolute and stress its metaphysical quality and its close relation to the supernatural. Furthermore, music is supposed to be no longer dependent on the other arts, and music releases the listener or the musician from prosaic everyday life. As Wackenroder writes in Die Wunder der Tonkunst, […] [a]ll sickening thoughts which, according to Wackenroder, are the illness of mankind vanish with a piece of music, making our mind sane again. Literary romanticism here recurs to a long tradition that reaches back to the classical ages in Greece and Arabia: Music is used as a remedy for curing illnesses of various kinds. In classical antiquity, Apollo is the god of music, poetry and dancing as well as the god of healing. He was also named “Iatros” (physician) or Apollo Medicus. […] Orpheus as a bard and demigod was also said to be capable of curing diseases by means of his music. […] Thus, music in history is part of treating physical illness on the one hand, but on the other hand is more and more considered to provide a remedy especially for mental deficiencies. Music is meant to improve nervous disorders and sometimes it is even prescribed as a regular medicine. As we will see in Hoffmann’s text Die Genesung, there is a connection between the ritual healing processes in the temples of Aesculapius and the setting of the forest in which the old man regains his health.
A new genus and species of armored scale insect (Hemiptera: Diaspididae), Protomorgania koebelei.
Dooley and Evans, is described and illustrated from specimens collected by Albert Koebele on Pittosporum sp.
(Pittosporaceae) in Australia around the year 1900. A key to the genera of armored scale insects similar to Protomorgania
and known to occur in Australia is provided.
A biodiversity inventory of the Lepidoptera of Pico Bonito National Park and vicinity, in the Department of Atlantida of northern Honduras, was initiated in 2009 to obtain baseline data. We present a revised checklist of Honduran butterfly species (updated from the initial 1967 lists), as well as the first comprehensive list of Honduran moths. Our updated list includes 550 species of Papilionoidea, 311 Hesperioidea, and 1,441 moth species.
Two species of the genus Sisyra Burmeister (Neuroptera: Sisyridae), S. cameroonensis, n. sp., and S. gruwelli, n. sp., are described from the African Republic of Cameroon. Sisyra pallida Meinander is synonymized with Sisyra delicata Smithers, new synonymy, after comparison of the types of the former with topotypic paratypes of the latter. Type material of Sisyra nilotica Tjeder appears to be lost. Examples of Sisyra are recorded from Nigeria, Ethiopia and Uganda. A second species of the endemic African genus, Sisyborina, Monserrat, S. scitula, n. sp., is described from Cameroon, Guinea, and Zambia.
Zürich, 22. März 1937 - im ersten Stock des renommierten Herrenausstatters "London House" probiert Thomas Mann gerade einen neuen Anzug an, als ihn ein Verkäufer informiert, dass im Erdgeschoss Gerhart Hauptmann eingetroffen sei. "Möchten Sie ihn sehen?" Nach kurzem Zögern lehnt Thomas Mann ab - mit den Worten: "Ach, da wollen wir vielleicht doch andere Zeiten abwarten." Replik des Verkäufers: "Genau das hat Herr Hauptmann auch gesagt." Die Zürcher Nicht-Begegnung der beiden Nobelpreisträger ist in verschiedener Hinsicht bemerkenswert. Schließlich handelte es sich nicht nur um die international bekanntesten deutschen Schriftsteller, sondern auch um alte Bekannte. Und jeder von beiden hatte dem anderen manches zu verdanken. Warum also wollten die beiden einander nicht begegnen?
Um die literaturgeschichtliche Bedeutung der Situation im Zürcher Herrengeschäft einschätzen zu können, muss man die gesamte Beziehung zwischen beiden in den Blick fassen. Sie könnte wechselvoller kaum sein. Nach dreißig Jahren kollegialer, phasenweise nahezu freundschaftlicher Verbundenheit brach der Kontakt abrupt ab und wurde bis zu Hauptmanns Tod 1946 nicht mehr aufgenommen. Nach dem Ableben des älteren Kollegen ändert sich Thomas Manns Sicht auf Gerhart Hauptmann jedoch wieder. Und – soviel vorweg – dabei spielten Jubiläumsgeburtstage stets eine wichtige Rolle. Ich gehe zunächst auf die Phase der engen Bekanntschaft ein; im zweiten Teil dann auf die Umstände des Abbruchs der Beziehungen. Dabei soll vor allem der letzte Kontaktversuch genauer analysiert werden. Ein resümierender Blick auf die dritte Phase steht am Ende dieser Überlegungen. ...
Das hethitische Phonem /xw/
(2014)
In the Hittite phonological system there was a labialized velar fricative /xw/ beside the plain velar fricative /x/ parallel to the opposition between the velar stops /kw/ and /k/. The frequent syllable /xwa/ was spelled either hu-(u) or hu-wa. Evidence from the frequency of words with initial hu in the lexicon, from spelling variations and from ablaut alternations is presented to demonstrate the existence of /xw/. It is suggested that Hittite /xw/ regularly corresponds to the reflexes of *w in the non-Anatolian Indo-European languages.
Die Bedeutung des philosophischen Programms John McDowells, das schon in der theoretischen Philosophie eine revolutionäre Neuausrichtung vornimmt, kann erst voll erkannt werden, wenn man auch seine Konsequenzen für die praktische Philosophie in den Blick nimmt. Zwar geht Geist und Welt primär von Dilemmata der Erkenntnistheorie aus. Aus McDowells Vorschlag, die Gleichsetzung der äußeren Natur mit dem bedeutungsfreien Raum der Naturgesetze zugunsten einer Konzeption von Gründen in der Welt aufzugeben, ergibt sich aber die Möglichkeit einer so neuartigen Perspektive auf die Natur moralischer Urteile, dass es fast so scheint, als sei McDowells theoretisches Programm auf diesen Gewinn für die praktische Philosophie hin angelegt worden.
FRAUEN.SCHREIBEN. So hieß das Thema des Symposiums, in dessen Zusammenhang dieser Text entstand. Die Frage, wie "Frau" in Texten von Schriftstellerinnen aus Österreich und China "geschrieben" wird, sollte dabei in den Blick genommen werden - Elfriede Jelinek stand dabei mit im Fokus der Analysen und ist auch meine Wahl im nachfolgenden Text. Diese Frage, nach dem "Wie-Frauen-Schreiben", die zunächst scheinbar recht simpel und unproblematisch gestellt werden kann, evoziert eine komplexe Auseinandersetzung mit Themen und Problemen, die der Literaturwissenschaft und Literaturtheorie konstitutiv zugrunde liegen - Fragen etwa nach einer potentiellen ('weiblichen') Autorschaft, einer 'weiblichen' Ästhetik, Fragen der Repräsentation 'von Frauen', hier im Besonderen 'in Texten von Frauen'.
A three-dimensional gridded climatology of carbon monoxide (CO) has been developed by trajectory mapping of global MOZAIC-IAGOS in situ measurements from commercial aircraft data. CO measurements made during aircraft ascent and descent, comprising nearly 41 200 profiles at 148 airports worldwide from December 2001 to December 2012 are used. Forward and backward trajectories are calculated from meteorological reanalysis data in order to map the CO measurements to other locations, and so to fill in the spatial domain. This domain-filling technique employs 15 800 000 calculated trajectories to map otherwise sparse MOZAIC-IAGOS data into a quasi-global field. The resulting trajectory-mapped CO dataset is archived monthly from 2001–2012 on a grid of 5° longitude × 5° latitude × 1 km altitude, from the surface to 14 km altitude.
The mapping product has been carefully evaluated, by comparing maps constructed using only forward trajectories and using only backward trajectories. The two methods show similar global CO distribution patterns. The magnitude of their differences is most commonly 10 % or less, and found to be less than 30 % for almost all cases. The trajectory-mapped CO dataset has also been validated by comparison profiles for individual airports with those produced by the mapping method when data from that site are excluded. While there are larger differences below 2 km, the two methods agree very well between 2 and 10 km with the magnitude of biases within 20 %.
Maps are also compared with Version 6 data from the Measurements Of Pollution In The Troposphere (MOPITT) satellite instrument. While agreement is good in the lowermost troposphere, the MOPITT CO profile shows negative biases of ∼ 20 % between 500 and 300 hPa. These upper troposphere biases are not related to the
mapping procedure, as almost identical differences are found with the original in situ MOZAIC-IAGOS data. The total CO trajectory-mapped MOZAIC-IAGOS climatology column agrees with the MOPITT CO total column within ±5 %, which is consistent with previous reports.
The maps clearly show major regional CO sources such as biomass burning in the central and southern Africa and anthropogenic emissions in eastern China. The dataset shows the seasonal CO cycle over different latitude bands and altitude ranges that are representative of the regions as well as long-term trends over latitude bands. We observe a decline in CO over the Northern Hemisphere extratropics and the tropics consistent with that reported by previous studies.
Similar maps have been made using the concurrent O3 measurements by MOZAICIAGOS, as the global variation of O3–CO correlations can be a useful tool for the evaluation of ozone sources and transport in chemical transport models. We anticipate use of the trajectory-mapped MOZAIC-IAGOS CO dataset as an a priori climatology for satellite retrieval, and for air quality model validation and initialization.
Tibnīn was an important small Crusader fief and a fortified castle. It was vital for the Kingdom of Jerusalem, because it included fertile agricultural lands, was a tax collection centre, and because it controlled the Damascus-to-Tyre commercial route. Additionally, its castle played defensive and offensive role in the north of the Kingdom of Jerusalem and upper Galilee, and its rulers of Tibnīn played a major role in forming the history of the Latin East. When the Crusaders invaded the Levant at the end of the eleventh century, it was given rise to new demographic, cultural, socio-economic, and architectural features. The present Paper aims at removing some of the mystery concerning the fief of Tibnīn and its castle in the Latin East. This paper thus is a study of the demographic structure of Tibnīn and discusses the socio-economic role of Tibnīn in the Latin east. Moreover, the role of Tibnīn in influencing the relations between Muslims and the Crusaders in the Levant and the architecture of the castle of Tibnīn and its importance in the age of the Crusade will be examined.
El libro pretende brindar un recorrido inicial a través de la fauna de arañas de la Argentina. Está organizado en veintiún capítulos. En el primero de ellos se presentan características generales de las arañas. Cada uno de los capítulos siguientes corresponde a una familia distinta. Se exponen aspectos morfológicos, fisiológicos y etológicos, entre otros. Las arañas de interés sanitario presentes en el país se encuentran incluidas. El libro cuenta con más de 120 fotografías, todas fueron realizadas por el autor, y hasta ahora no habían sido publicadas. La obra está dirigida a todos los que se interesan por el mundo de las arañas, en particular a estudiantes y profesionales de ciencias biológicas, médicas y afines.
Repertorium
(2015)
Register
(2015)
Nach dem zweiten Weltkrieg war das Stadtzentrum Frankfurt am Main fast vollkommen zerstört worden. In den Nachkriegsjahren war nun fraglich, wie die Stadt von den Trümmermassen befreit werden sollte. Der Straßenraum musste von Schutt geräumt werden, Krankenhäuser und Versorgungseinrichtungen mussten wiederhergestellt werden und es musste neuer Wohnraum geschaffen werden. Es herrschte großer Baumaterialmangel, dass damals als großes Problem galt. Über eine Wiederverwertung des Trümmerschutts und die Verarbeitung zu neuen Baustoffen machte sich der damals amtierende Bürgermeister Kurt Blaum im Sommer 1945 die ersten Gedanken. Am 18. Oktober 1945 beschloss man in einer geheimen Sitzung die Gründung der Trümmerverwertungsgesellschaft. Die Aufgaben der Trümmerverwertungsgesellschaft wurde klar festgehalten: 1) Abbruch von Gefahrenstellen, Leitung der Trümmergewinnung und Transport zur Verwertungsanlage 2) Forschung zur Verwertung von Trümmerschutt 3) Errichtung und Betrieb der Aufbereitungsanlage sowie das Betonwerks.
Auf einem 10 Hektar großen Baugelände im Frankfurter Riederwald wurde die Trümmerverwertungsanlage gebaut. Zunächst wurde eine provisorische Aufbereitungsanlage gebaut, die 1947 in Betrieb war. Nach der Fertigstellung der Aufbereitungs- und Sinteranlage sowie das Betonwerk im Jahr 1950, wurde die provisorische Anlage zurückgebaut.
Die Philipp Holzmann AG war einer ihrer Gründer und trug ihren Teil zum Wiederaufbau der Stadt bei.
A three-dimensional gridded climatology of carbon monoxide (CO) has been developed by trajectory mapping of global MOZAIC-IAGOS in situ measurements from commercial aircraft data. CO measurements made during aircraft ascent and descent, comprising nearly 41 200 profiles at 148 airports worldwide from December 2001 to December 2012, are used. Forward and backward trajectories are calculated from meteorological reanalysis data in order to map the CO measurements to other locations and so to fill in the spatial domain. This domain-filling technique employs 15 800 000 calculated trajectories to map otherwise sparse MOZAIC-IAGOS data into a quasi-global field. The resulting trajectory-mapped CO data set is archived monthly from 2001 to 2012 on a grid of 5° longitude × 5° latitude × 1 km altitude, from the surface to 14 km altitude.
The mapping product has been carefully evaluated, firstly by comparing maps constructed using only forward trajectories and using only backward trajectories. The two methods show similar global CO distribution patterns. The magnitude of their differences is most commonly 10 % or less and found to be less than 30 % for almost all cases. Secondly, the method has been validated by comparing profiles for individual airports with those produced by the mapping method when data from that site are excluded. While there are larger differences below 2 km, the two methods agree very well between 2 and 10 km with the magnitude of biases within 20 %. Finally, the mapping product is compared with global MOZAIC-IAGOS cruise-level data, which were not included in the trajectory-mapped data set, and with independent data from the NOAA aircraft flask sampling program. The trajectory-mapped MOZAIC-IAGOS CO values show generally good agreement with both independent data sets.
Maps are also compared with version 6 data from the Measurements Of Pollution In The Troposphere (MOPITT) satellite instrument. Both data sets clearly show major regional CO sources such as biomass burning in Central and southern Africa and anthropogenic emissions in eastern China. While the maps show similar features and patterns, and relative biases are small in the lowermost troposphere, we find differences of ∼ 20 % in CO volume mixing ratios between 500 and 300 hPa. These upper-tropospheric biases are not related to the mapping procedure, as almost identical differences are found with the original in situ MOZAIC-IAGOS data. The total CO trajectory-mapped MOZAIC-IAGOS column is also higher than the MOPITT CO total column by 12–16 %.
The data set shows the seasonal CO cycle over different latitude bands and altitude ranges as well as long-term trends over different latitude bands. We observe a decline in CO over the northern hemispheric extratropics and the tropics consistent with that reported by previous studies using other data sources.
We anticipate use of the trajectory-mapped MOZAIC-IAGOS CO data set as an a priori climatology for satellite retrieval and for air quality model validation and initialization.
Unequivocal international guidelines regarding the diagnosis and management of patients with acute appendicitis are lacking. The aim of the consensus meeting 2015 of the EAES was to generate a European guideline based on best available evidence and expert opinions of a panel of EAES members. After a systematic review of the literature by an international group of surgical research fellows, an expert panel with extensive clinical experience in the management of appendicitis discussed statements and recommendations. Statements and recommendations with more than 70 % agreement by the experts were selected for a web survey and the consensus meeting of the EAES in Bucharest in June 2015. EAES members and attendees at the EAES meeting in Bucharest could vote on these statements and recommendations. In the case of more than 70 % agreement, the statement or recommendation was defined as supported by the scientific community. Results from both the web survey and the consensus meeting in Bucharest are presented as percentages. In total, 46 statements and recommendations were selected for the web survey and consensus meeting. More than 232 members and attendees voted on them. In 41 of 46 statements and recommendations, more than 70 % agreement was reached. All 46 statements and recommendations are presented in this paper. They comprise topics regarding the diagnostic work-up, treatment indications, procedural aspects and post-operative care. The consensus meeting produced 46 statements and recommendations on the diagnostic work-up and management of appendicitis. The majority of the EAES members supported these statements. These consensus proceedings provide additional guidance to surgeons and surgical residents providing care to patients with appendicitis.
Neural responses to heartbeats in the default network encode the self in spontaneous thoughts
(2016)
The default network (DN) has been consistently associated with self-related cognition, but alsoto bodily state monitoring and autonomic regulation. We hypothesized that these two seemingly disparate functional roles of the DN are functionally coupled, in line with theories proposing that selfhood is grounded in the neural monitoring of internal organs, such as the heart. We measured with magnetoencephalograhy neural responses evoked by heartbeats while human participants freely mind-wandered. When interrupted by a visual stimulus at random intervals, participants scored the self-relatedness of the interrupted thought. They evaluated their involvement as the firstperson perspective subject or agent inthethought (“I”), and on another scaleto what degreethey werethinking aboutthemselves (“Me”). During the interrupted thought, neural responses to heartbeats in two regions of the DN, the ventral precuneus and the ventromedial prefrontal cortex, covaried, respectively, with the “I” and the “Me” dimensions of the self, even at the single-trial level. No covariation between self-relatedness and peripheral autonomic measures (heart rate, heart rate variability, pupil diameter, electrodermal activity, respiration rate, and phase) or alpha power was observed. Our results reveal a direct link between selfhood and neural responses to heartbeats in the DN and thus directly support theories grounding selfhood in the neural monitoring of visceral inputs. More generally, the tight functional coupling between self-related processing and cardiac monitoring observed here implies that, even in the absence of measured changes in peripheral bodily measures, physiological and cognitive functions have to be considered jointly in the DN.
The article consists in a comparative reading of three novels: Um rio chamado tempo by Mia Couto, Le pain des corbeaux by Lhoussain Azergui and Paw królowej by Dorota Masłowska. In spite of the difference of the historical circumstances of Mozambique, Morocco and Poland, these three books meet at an intersecting point: the emergence of an intelligentsia that uses literacy and writing as an instrument to deconstruct the post-colonial concept of nation and to operate a trans-colonial renegotiation of identity. By the notion of trans-colonial, I understand the opposition against new kinds of symbolic violence that emerged after the end of the colonial period; here this new form of oppression is related to the concept of national unity – an artificial construct that leaves no place for a dualism or pluralism of cultural reality (two shores of the Zambezi river, Arab and Berber dualism in Morocco, "small homelands" in Poland).
The young heroes of the novels grasp the pen in order to break through the falseness or the taboos created by the fathers, establishing, at the same time, the relation of solidarity with the world of the grandfathers. The act of writing becomes an actualization of the ancestral universe of magic. The settlement of accounts with the parental generation concerns the vision of nation built upon the resistance against the colonizer (it also refers to the Polish cultural formation, based on the tradition of uprisings and resistance against the Russians).
The early acquisition of Greek compounds by two monolingual Greek girls aged between 1;8 and 3;0 years is studied in a usage-based theoretical framework. Special importance is attached to the morphological structure of Greek compound types occurring in child speech and child-directed speech. Greek nominal compound formation does not consist in the mere juxtaposition of words or roots, but involves stems as well as a compound marker. Major questions addressed are the transparency of compounds and productive nominal compound formation. Evidence for productivity of nominal compound formation has been found with only one of the two girls. In contrast to other languages, neoclassical nominal compounds by far exceed endocentric subordinative ones tokenwise in Greek child speech and child-directed speech providing evidence of entrenchment rather than productivity.
In a cross-linguistic comparison it is shown that, in spite of the fact that both Standard Modern Greek and German are rich in nominal compounds, their number is much more limited in Greek than in German child speech. An explanation for this apparent paradox is provided by an onomasiological approach to lexical typology based on a sample list of nominal compounds occurring in German child language and their Greek translational equivalents. It has been found that while use of nominal compounds is common in colloquial German including child-centered situations, it is more typical of Greek formal than colloquial registers.
"Ja, Goethe über alles und immer!" : Benns "Doppelleben" in den Briefen an F. W. Oelze (1932-1956)
(2016)
"Goethe über alles"! Das will heißen, mit einer kaum versteckten Anspielung auf die deutsche Nationalhymne: Goethe vor allem über Deutschland! Diese emphatische Parole Gottfried Benns findet sich in seinem Brief vom 8. November 1950 an Friedrich Wilhelm Oelze.1 Zu dieser Zeit stand der Briefwechsel zwischen den beiden Männern schon in seinem achtzehnten Jahr, ausgelöst durch das Goethe-Jahr 1932, zu dem Benn seinen Essay "Goethe und die Naturwissenschaften" beigesteuert hatte. Er erschien in der "Neuen Rundschau" in einem "Sonderheft zum hundertsten Todestag Goethes" und enthielt u. a. Beiträge von Gerhart Hauptmann, Thomas Mann, Hermann Hesse, André Gide und Ortega y Gasset. Benn war zeitlebens stolz auf diese Leistung und ihre illustre Autoren-Nachbarschaft.
The first step in methanol metabolism in methylotrophic yeasts, the oxidation of methanol and higher alcohols with molecular oxygen to formaldehyde and hydrogen peroxide, is catalysed by alcohol oxidase (AOX), a 600-kDa homo-octamer containing eight FAD cofactors. When these yeasts are grown with methanol as the carbon source, AOX forms large crystalline arrays in peroxisomes. We determined the structure of AOX by cryo-electron microscopy at a resolution of 3.4 Å. All residues of the 662-amino acid polypeptide as well as the FAD are well resolved. AOX shows high structural homology to other members of the GMC family of oxidoreductases, which share a conserved FAD binding domain, but have different substrate specificities. The preference of AOX for small alcohols is explained by the presence of conserved bulky aromatic residues near the active site. Compared to the other GMC enzymes, AOX contains a large number of amino acid inserts, the longest being 75 residues. These segments are found at the periphery of the monomer and make extensive inter-subunit contacts which are responsible for the very stable octamer. A short surface helix forms contacts between two octamers, explaining the tendency of AOX to form crystals in the peroxisomes.
Sprachen, Epochen und Gattungen stellt die Literaturwissenschaften immer wieder vor die Frage, wie sie diese Entwicklung mitgestalten und zu ihrem Vorteil nutzen können. Dabei ist digital nicht gleich digital, sondern es existiert eine Vielzahl sehr unterschiedlicher, digitaler Repräsentationsformen von Text. Nur wenige dieser Repräsentationsformen werden literaturwissenschaftlichen Anforderungen tatsächlich gerecht, darunter diejenige, die den Richtlinien der Text Encoding Initiative folgt. Der vorliegende Beitrag vergleicht zunächst einige derzeit gängige digitale Repräsentationsformen von Text. Für literaturwissenschaftliche Forschung besonders geeignet erweist sich hierbei eine Repräsentationsform, die den Richtlinien der Text Encoding Initiative folgt. Daher informiert der Beitrag anschließend über deren Nutzen für die literaturwissenschaftliche Arbeit, sowohl im Bereich der wissenschaftlichen Textedition als auch im Bereich der Analyse und Interpretation von Texten. Nur wenn die Literaturwissenschaften in ihrer Breite den Nutzen von offenen, expressiven, flexiblen und standardisierten, langfristig nutzbaren Formaten für die Forschung erkennen, können sie sich mit dem erforderlichen Nachdruck für deren Verbreitung einsetzen und durch die zunehmende Verfügbarkeit von Texten in solchen Formaten für die eigene Forschung und Lehre davon profitieren.
Decreased STARD10 expression is associated with defective insulin secretion in humans and mice
(2017)
Genetic variants near ARAP1 (CENTD2) and STARD10 influence type 2 diabetes (T2D) risk. The risk alleles impair glucose-induced insulin secretion and, paradoxically but characteristically, are associated with decreased proinsulin:insulin ratios, indicating improved proinsulin conversion. Neither the identity of the causal variants nor the gene(s) through which risk is conferred have been firmly established. Whereas ARAP1 encodes a GTPase activating protein, STARD10 is a member of the steroidogenic acute regulatory protein (StAR)-related lipid transfer protein family. By integrating genetic fine-mapping and epigenomic annotation data and performing promoter-reporter and chromatin conformational capture (3C) studies in β cell lines, we localize the causal variant(s) at this locus to a 5 kb region that overlaps a stretch-enhancer active in islets. This region contains several highly correlated T2D-risk variants, including the rs140130268 indel. Expression QTL analysis of islet transcriptomes from three independent subject groups demonstrated that T2D-risk allele carriers displayed reduced levels of STARD10 mRNA, with no concomitant change in ARAP1 mRNA levels. Correspondingly, β-cell-selective deletion of StarD10 in mice led to impaired glucose-stimulated Ca2+ dynamics and insulin secretion and recapitulated the pattern of improved proinsulin processing observed at the human GWAS signal. Conversely, overexpression of StarD10 in the adult β cell improved glucose tolerance in high fat-fed animals. In contrast, manipulation of Arap1 in β cells had no impact on insulin secretion or proinsulin conversion in mice. This convergence of human and murine data provides compelling evidence that the T2D risk associated with variation at this locus is mediated through reduction in STARD10 expression in the β cell.
Body image dissatisfaction is a serious, global problem that negatively affects life satisfaction. Several claims have been made about the possible psychological benefits of naturist activities, but very little empirical research has investigated these benefits or any plausible explanations for them. In three studies—one large-scale, cross-sectional study (n = 849), and 2 prospective studies (n = 24, n = 100) this research developed and applied knowledge about the possible benefits of naturist activities. It was found that more participation in naturist activities predicted greater life satisfaction—a relationship that was mediated by more positive body image, and higher self-esteem (Study 1). Applying these findings, it was found that participation in actual naturist activities led to an increase in life satisfaction, an effect that was also mediated by improvements in body image and self-esteem (Studies 2 and 3). The potential benefits of naturism are discussed, as well as possible future research, and implications for the use of naturist activities.
In evidence-based weight-loss programs weight regain is common after an initial weight reduction. Eating slowly significantly lowers meal energy intake and hunger ratings. Despite this knowledge, obese individuals do not implement this behaviour. We, thus tested the hypothesis of changing eating behaviour with an intra-oral medical device leading to constant weight reduction in overweight and obesity.
Six obese patients (6 men, age 56 ± 14, BMI 29 ± 2 kg / m2) with increased CVRF profile were included in this prospective study. All patients had been treated for obesity during the last 10 years in a single centre and had at least 3 frustrate evidence-based diets. Patients received a novel non-invasive intra-oral medical device to slow eating time. Further advice included not to count calories, to avoid any other form of diet, to take their time with their meals, and to eat whatever they liked.
This device was used only during meals for the first 4 to 8 weeks for a total of 88 [20–160] hours. Follow-up period was 23 [15–38] months. During this period, patients lost 11% [5–20%] (p<0.001) of their initial weight. At 12 months, all patients had lost >5%, and 67% (4/6) achieved a >10% bodyweight loss. In the course of the study, altered eating patterns were observed. There were no complications with the medical device. Of note, all patients continued to lose weight after the initial intervention period (p<0.001) and none of them had weight regain.
With this medical device, overweight and obese patients with a history of previously frustrating attempts to lose weight achieved a significant and sustained weight loss over two years. These results warrant the ongoing prospective randomised controlled trial to prove concept and mechanism of action.
Background: Only few authors have analyzed the impact of workplace conflicts and the resulting stress on the risk of developing cardiovascular disorders. The goal of this study was to analyze the association between workplace conflicts and cardiovascular disorders in patients treated by German general practitioners.
Methods: Patients with an initial documentation of a workplace conflict experience between 2005 and 2014 were identified in 699 general practitioner practices (index date). We included only those who were between the ages of 18 and 65 years, had a follow-up time of at least 180 days after the index date, and had not been diagnosed with angina pectoris, myocardial infarction, coronary heart diseases, or stroke prior to the documentation of the workplace mobbing. In total, the study population consisted of 7,374 patients who experienced conflicts and 7,374 controls for analysis. The main outcome measure was the incidence of angina pectoris, myocardial infarction, and stroke correlated with workplace conflict experiences.
Results: After a maximum of five years of follow-up, 2.9% of individuals who experienced workplace conflict were affected by cardiovascular diseases, while only 1.4% were affected in the control group (p-value <0.001). Workplace conflict was associated with a 1.63-fold increase in the risk of developing cardiovascular diseases. Finally, the impact of workplace conflict was higher for myocardial infarction (OR=2.03) than for angina pectoris (OR=1.79) and stroke (OR=1.56).
Conclusions: Overall, we found a significant association between workplace conflicts and cardiovascular disorders.
Expression of surfactant protein B is dependent on cell density in H441 lung epithelial cells
(2017)
Background: Expression of surfactant protein (SP)-B, which assures the structural stability of the pulmonary surfactant film, is influenced by various stimuli, including glucocorticoids; however, the role that cell-cell contact plays in SP-B transcription remains unknown. The aim of the current study was to investigate the impact of cell-cell contact on SP-B mRNA and mature SP-B expression in the lung epithelial cell line H441.
Methods: Different quantities of H441 cells per growth area were either left untreated or incubated with dexamethasone. The expression of SP-B, SP-B transcription factors, and tight junction proteins were determined by qPCR and immunoblotting. The influence of cell density on SP-B mRNA stability was investigated using the transcription inhibitor actinomycin D.
Results: SP-B mRNA and mature SP-B expression levels were significantly elevated in untreated and dexamethasone-treated H441 cells with increasing cell density. High cell density as a sole stimulus was found to barely have an impact on SP-B transcription factor and tight junction mRNA levels, while its stimulatory ability on SP-B mRNA expression could be mimicked using SP-B-negative cells. SP-B mRNA stability was significantly increased in high-density cells, but not by dexamethasone alone.
Conclusion: SP-B expression in H441 cells is dependent on cell-cell contact, which increases mRNA stability and thereby potentiates the glucocorticoid-mediated induction of transcription. Loss of cell integrity might contribute to reduced SP-B secretion in damaged lung cells via downregulation of SP-B transcription. Cell density-mediated effects should thus receive greater attention in future cell culture-based research.
In 1983, Brian Henderson published an article that examined various types of narrative structure in film, including flashbacks and flashforwards. After analyzing a whole spectrum of techniques capable of effecting a transition between past and present – blurs, fades, dissolves, and so on – he concluded: "Our discussions indicate that cinema has not (yet) developed the complexity of tense structures found in literary works". His "yet" (in parentheses) was an instance of laudable caution, as very soon – in some ten–fifteen years – the situation would change drastically, and temporal twists would become a trademark of a new genre that has not (yet) acquired a standardized name: "modular narratives", "puzzle films", and "complex films" are among the labels used.
Der Artikel stellt aktuelle stilometrische Studien im Delta-Kontext vor. Diskutiert wird, warum die Verwendung des Kosinus-Abstands zu einer Verbesserung der Erfolgsquote führt; durch Experimente zur Vektornormalisierung gelingt es, die Funktionsweise von Delta besser zu verstehen. Anhand von mittelhochdeutschen Texten wird gezeigt, dass auch metrische Eigenschaften zur Autorschaftsattribution eingesetzt werden können. Zudem wird untersucht, inwieweit die mittelalterliche, nicht-normierte Schreibung die Erfolgsquote von Delta beeinflusst. Am Beispiel von arabisch-lateinischen Übersetzungen wird geprüft, inwieweit eine selektive Merkmalseliminierung dazu beitragen kann, das Übersetzersignal vom Genresignal zu isolieren.
Earliest expansion of animal husbandry beyond the Mediterranean zone in the sixth millennium BC
(2017)
Since their domestication in the Mediterranean zone of Southwest Asia in the eighth millennium BC, sheep, goats, pigs and cattle have been remarkably successful in colonizing a broad variety of environments. The initial steps in this process can be traced back to the dispersal of farming groups into the interior of the Balkans in the early sixth millennium BC, who were the first to introduce Mediterranean livestock beyond its natural climatic range. Here, we combine analysis of biomolecular and isotopic compositions of lipids preserved in prehistoric pottery with faunal analyses of taxonomic composition from the earliest farming sites in southeast Europe to reconstruct this pivotal event in the early history of animal husbandry. We observe a marked divergence between the (sub)Mediterranean and temperate regions of Southeast Europe, and in particular a significant increase of dairying in the biochemical record coupled with a shift to cattle and wild fauna at most sites north of the Balkan mountain range. The findings strongly suggest that dairying was crucial for the expansion of the earliest farming system beyond its native bioclimatic zone.
In dem folgenden werkgenetischen und forschungskritischen Beitrag geht es um das sonderbare und revisionsbedürftige Schicksal, das eine von Mozart nach dessen Rückkehr aus Mannheim in Salzburg ohne Auftrag begonnene und bis Sommer 1780 fast vollendete Oper durch ihre Rezeption bei der Nachwelt bis heute erlitten hat. Für meine Hypothese, bei Mozarts Zaïde handele es sich um eine ernste (nicht-komische), höchstwahrscheinlich einaktig konzipierte Kurzoper ("Operette", W. A. M.) ohne glücklichen Ausgang, ist es ebenso unmöglich, einen "Nachweis" zu erbringen, wie für die bisher geltende, als einzig denkbare Wahrheit auftretende These, sie sei ein stark fragmentarisches, höchstwahrscheinlich dreiaktiges Singspiel, dem nicht nur die Ouvertüre und die meisten Dialoge fehlten, sondern auch die entweder in mehreren fehlenden Schlussnummern eines zweiten oder in einem dritten Akt sich vollziehen sollende glückliche Wende. Darum wird hier nicht versucht, gegen eine bestehende beanspruchte "Deutungshoheit" eine andere zu setzen, sondern lediglich angezeigt und begründet, warum es ratsam ist, eine andere Interpretationsmöglichkeit bekannter Quellen, von denen einige bisher berücksichtigt, andere vernachlässigt wurden, ins Auge zu fassen. Es kann lediglich anhand von Indizien, welche die Quellen und Teile der bisherigen Forschung aufweisen, eine neue, bisher verworfene Möglichkeit von dem über sie verhängten Verdikt befreit werden. ...
Schiller and Goethe have very different conceptions of tragedy. In his play Don Carlos, Schiller, especially in the character of Philip II, shows us the conflict between blood and positive law. In Goethe´s novel Elective Affinities, the individual will is ignorant of fate and helpless against it. So to speak, Schiller applies the "Antigone´s Model" and Goethe applies the "Oedipus Model". In his dramatic vision of the conflict, Schiller is inspired by Shakespeare´s plays. However, Goethe´s point of view is based on his reflections on Natural Philosophy.
Background: Kyrgyzstan, where HIV is concentrated in prisons and driven by injection drug use, provides a prison-based methadone maintenance therapy program as well as abstinence-oriented therapeutic community based on the 12-step model called the “Clean Zone.” We aimed to qualitatively assess how prisoners navigate between these treatment options to understand the persistence of the Clean Zone despite a lack of evidence to support its effectiveness in treating opioid use disorders.
Methods: We conducted an analysis of policy documents and over 60 h of participant observation in February 2016, which included focus groups with a convenience sample of 20 therapeutic community staff members, 110 prisoners across three male and one female prisons, and qualitative interviews with two former Clean Zone participants. Field notes containing verbatim quotes from participants were analyzed through iterative reading and discussion to understand how participants generally perceive the program, barriers to entry and retention, and implications for future treatment within prisons.
Results: Our analyses discerned three themes: pride in the mission of the Clean Zone, idealism regarding addiction treatment outcomes against all odds, and the demonization of methadone.
Conclusion: Despite low enrollment and lack of an evidence base, the therapeutic community is buttressed by the strong support of the prison administration and its clients as an “ordered” alternative to what is seen as chaotic life outside of the Clean Zone. The lack of services for Clean Zone patients after release likely contributes to high rates of relapse to drug use. The Clean Zone would benefit from integration of stabilized methadone patients combined with a post-release program.
Testing for liver-related autoantibodies should be included in the workup of patients with hepatitis or cholestasis of unknown origin. Although most of these autoantibodies are not disease specific, their determination is a prerequisite to diagnose autoimmune hepatitis (AIH) and primary biliary cholangitis (PBC), and they are components of the diagnostic scoring system in these diseases. In primary sclerosing cholangitis (PSC), on the other hand, autoantibodies are frequently present but play a minor role in establishing the diagnosis. In PSC, however, data on antibodies suggest a link between disease pathogenesis and the intestinal microbiota. This review will focus on practical aspects of antibody testing in the three major autoimmune liver diseases AIH, PBC, and PSC.
In AD 79 the town of Herculaneum was suddenly hit and overwhelmed by volcanic ash-avalanches that killed all its remaining residents, as also occurred in Pompeii and other settlements as far as 20 kilometers from Vesuvius. New investigations on the victims' skeletons unearthed from the ash deposit filling 12 waterfront chambers have now revealed widespread preservation of atypical red and black mineral residues encrusting the bones, which also impregnate the ash filling the intracranial cavity and the ash-bed encasing the skeletons. Here we show the unique detection of large amounts of iron and iron oxides from such residues, as revealed by inductively coupled plasma mass spectrometry and Raman microspectroscopy, thought to be the final products of heme iron upon thermal decomposition. The extraordinarily rare preservation of significant putative evidence of hemoprotein thermal degradation from the eruption victims strongly suggests the rapid vaporization of body fluids and soft tissues of people at death due to exposure to extreme heat.
Background: Bacterial meningitis is associated with high mortality and long-term neurological sequelae. Increasing the phagocytic activity of microglia could improve the resistance of the CNS against infections. We studied the influence of activin A, a member of the TGF-β family with known immunoregulatory and neuroprotective effects, on the functions of microglial cells in vitro.
Methods: Primary murine microglial cells were treated with activin A (0.13 ng/ml–13 μg/ml) alone or in combination with agonists of TLR2, 4, and 9. Phagocytosis of Escherichia coli K1 as well as release of TNF-α, IL-6, CXCL1, and NO was assessed.
Results: Activin A dose-dependently enhanced the phagocytosis of Escherichia coli K1 by microglial cells activated by agonists of TLR2, 4, and 9 without further increasing NO and proinflammatory cytokine release. Cell viability of microglial cells was not affected by activin A.
Conclusions: Priming of microglial cells with activin A could increase the elimination of bacteria in bacterial CNS infections. This preventive strategy could improve the resistance of the brain to infections, particularly in elderly and immunocompromised patients.
Lymphangioleiomyomatosis (LAM) is a rare disease that generally affects young women and involves the abnormal proliferation of smooth muscle-like cells (LAM cells) in the lungs (pulmonary LAM) and extrapulmonary sites (extrapulmonary LAM). This disease is rare in males. It is hard to distinguish between lung cancer and pulmonary LAM, especially during early stages. Herein, we present a case of a 66-year-old man with a small nodule in the right upper lobe that was first diagnosed as a lung malignancy using a chest CT scan. After a wedge dissection, a pathologist performed a histologic and immunohistochemical examination, and a diagnosis of pulmonary LAM was made. We further performed a 518-gene panel analysis using next-generation sequencing, and only three genes, BARD1, BLM, and BRCA2, were found to have mutations. We also provide a summary of the diagnosis and treatment of this disease.
Die Bewertung der Nitrataustragsgefährdung (NAG) landwirtschaftlich genutzter Flächen in Wasserschutzgebieten (WSG) erfolgte bislang auf Basis bodenkundlicher Kartierungen und wurde seit 1996 nach einem im Staatsanzeiger für das Land Hessen veröffentlichten Merkblatt des ehemaligen Hessischen Landesamtes für Bodenforschung im Rahmen der Muster-Wasserschutzgebietsverordnung geregelt (HLfB 1996, HMUJFG 1996). Infolge der Verfügbarkeit hochauflösender Bodendaten in Form der „Bodenflächendaten 1: 5.000, landwirtschaftliche Nutzfläche“ (BFD5L) wird die Ermittlung der Nitrataustragsgefährdung landwirtschaftlich genutzter Flächen neu geregelt. Die BFD5L liefert Auswertungen der Bodenschätzungsdaten zur Feldkapazität des Wurzelraums sowie weiterer relevanter Parameter, die zur Bewertung der Nitrataustragsgefährdung herangezogen werden können.
Um die Eignung der BFD5L-Daten zur Ermittlung der Nitrataustragsgefährdung zu überprüfen, wurden in den Jahren 2009 bis 2012 bodenkundliche Vergleichskartierungen im Rahmen eines Pilotvorhabens im Wasserschutzgebiet Eschollbrücken/Pfungstadt in Südhessen, im Wassereinzugsgebiet der Quelle Meineringhausen bei Korbach, im Wasserschutzgebiet des Tiefbrunnens Spieß der Gemeinde Bad Emstal sowie im WSG Quelle Ohmes der Stadt Kirtorf durchgeführt. Ziel war es, die Umsetzungsmöglichkeiten bei der Nutzung der BFD5LDaten in organisatorischer und technischer Hinsicht zu erproben und das bisherige Verfahren zu überarbeiten (PETER & MILLER 2009, PETER & MILLER 2010a und 2010b, PETER & MILLER 2012).
Die Ergebnisse der Vergleichskartierungen zeigen, dass sich die Daten der BFD5L grundsätzlich für die Ermittlung der Nitrataustragsgefährdung in Wasserschutzgebieten eignen. Lediglich für Flächen, für die nach den bislang im System BFD5L enthaltenen Methoden keine Kennwerte abgeleitet werden können sowie für Sonderstandorte, muss die Nitrataustragsgefährdung durch bodenkundliche Geländearbeiten ermittelt werden.
Ḥoveret taḳtsirim : kenes ha-Ḥevrah ha-Geologit 2018 : Yiśraʿel-Ḳafrisin 25.03.2018 - 29.03.2018
(2018)
Purpose: DINO and DACOTA were prospective, noninterventional studies assessing the health status and quality of life of patients with COPD newly treated with roflumilast 500 µg once-daily add-on therapy.
Patients and methods: Patients were evaluated over 6 months. Clinical COPD questionnaire (CCQ) and COPD assessment test (CAT) scores were recorded at baseline and after 3 and 6 months. In DACOTA, post-bronchodilator FEV1 was recorded at each time point.
Results: Of 5,462 and 3,645 patients recruited into DINO and DACOTA, respectively, 3,274 patients in DINO and 916 patients in DACOTA completed the 6-month visit. Almost all patients had severe or very severe airway obstruction; mean baseline CCQ total score was 3.9 in DINO and 3.7 in DACOTA. Overall, 33.8% of patients in DACOTA and 30.6% in DINO discontinued treatment prematurely. Significant and clinically relevant improvements in CCQ total scores were observed in both studies (mean change from baseline of 1.36 in DINO and 0.91 in DACOTA at Month 6 [all P<0.001]). Changes in CAT total score from baseline to Month 6 indicated that the average clinical impact of COPD was reduced from a severe (score: 21–30) to a moderate (score: 11–20) impairment. In DACOTA, mean change in post-bronchodilator FEV1 was 202 mL (P<0.001). Diarrhea, nausea, and weight decrease were the most frequently reported adverse drug reactions.
Conclusion: In real-life clinical practice, roflumilast treatment as an add-on therapy is associated with clinically relevant improvements in health status and quality of life.
"Politische Korrektheit" ist als deskriptive wie als normative Kategorie in Bezug auf unterschiedlichste Kommunikations-, mediale und institutionelle Kontexte seit einigen Jahren allgegenwärtig. Zunehmend wird sie nun selbst zum Gegenstand der Debatte. Ursprünglich Ausdruck des Bemühens, ein Bewusstsein für sprachliche Diskriminierungen zu schaffen und auf eine diskriminierungsfreie Sprache hinzuwirken, befindet sich die politische Korrektheit mittlerweile im Spannungsfeld zwischen nahezu obsessiv betriebenen Versuchen einer Beschränkung des Sagbaren einerseits und ebenso programmatisch unternommenen Überschreitungen der Grenzen des Sagbaren andererseits. Verbot und Provokation grundieren nicht zuletzt das politische/ administrative Sprechen bzw. Schreiben sowie erhebliche Anteile von Äußerungsformen im Rahmen der Social Media. In einer historischen Perspektive verbindet die Forderung nach einer mehr oder weniger strikten Reglementierung des Sagbaren die politische Korrektheit mit der staatlichen oder kirchlichen Zensur vor- bzw. nicht-demokratischer Systeme. Während gegenwärtig in der Mehrzahl der westlichen Gesellschaften eine derart institutionalisierte Steuerung des Sagbaren nicht mehr stattfindet, also scheinbar nichts mehr "unsagbar" ist, lassen sich in verschiedenen sozialen Segmenten und Communities sehr wohl selbstauferlegte Sprach- und Verhaltenskodices beobachten, die nach wie vor oder wieder Grenzen des Sagbaren definieren. Als Sprachkodex in diesem Sinn fungiert bisweilen auch die politische Korrektheit. So fragwürdig eine zum Selbstzweck gewordene politisch korrekte Sprache allerdings auch sein mag, so besorgniserregend sind programmatische Verstöße gegen die politische Korrektheit, wo sie offensichtlich auf Diffamierung zielen und in letzter Konsequenz Prozesse der Entsolidarisierung befördern wollen. ...