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A remarkable feature of the collapse of the British Empire is that the British departed from almost every single one of their colonial territories invariably leaving behind a messy situation and an agenda of serious problems that in most cases still haunt those territories to this day. One such territory is the Southern British Cameroons. There, the British Government took the official view that the territory and its people were 'expendable'. It opposed, for selfish economic reasons, sovereign statehood for the territory, in clear violation of the UN Charter and the norm of self-determination. It transferred the Southern Cameroons to a new colonial overlord and hurriedly left the territory. The British Government's bad faith, duplicity, deception, wheeling and dealing, and betrayal of the people of the Southern Cameroons is incredible and defies good sense. Ample evidence of this is provided by the declassified documents in this book. Among the material are treaties concluded by Britain with Southern Cameroons coastal Kings and Chiefs; and the boundary treaties of the Southern Cameroons, treaties defining the frontiers with Nigeria to the west and the frontier with Cameroun Republic to the east. The book contains documents that attest to the Southern Cameroons as a fully self-governing country, ready for sovereign statehood. These include debates in the Southern Cameroons House of Assembly; and the various Constitutions of the Southern Cameroons. The book also reproduces British declassified documents on the Southern Cameroons covering the three critical years from 1959 to 1961, documents which speak to the inglorious stewardship of Great Britain in the Southern Cameroons. This book removes lingering doubts in some quarters that the people of the Southern Cameroons were cheated of independence. Its contents are further evidence of their inalienable right and sacred duty to assert their independence. No one who reads this book can possibly be indifferent to the just struggle of the Southern Cameroons for sovereign statehood.
Learner autonomy has been discussed since the 70th in the last century. It was argued, that learners should be familiar with foreign language learning, because language learning will get more and more important in a society of the future. So even after school time people should be able to develop foreign language skills without any formal teaching. In recent time a new concept has been added: teacher autonomy. Learner autonomy and teacher autonomy are interdependent. In other words: We can not develop learner autonomy without developing teacher autonomy. Our discussion starts with some simple facts. Gordon Wells observed in his famous Bristol Project several children for more than ten years and compared their language development and learning behaviour in two contexts: school and families. Interesting differences have been found. On the one hand children are more initiative and more curious in the family context. On the other hand they loose more and more initiatives through school experiences. The concepts of learner autonomy and teacher autonomy and consequences for teacher training will be discussed in the context of these findings.
Cream wurde bereits zu ihrer Gründung Mitte der 1960er Jahre von der Musikwelt als die erste "Supergroup" der Rockmusikgeschichte verstanden. Jack Bruce (Bass), Eric Clapton (Gitarre) und Ginger Baker (Schlagzeug), drei renommierte Musiker, die auf langjährige Erfahrungen in anderen Jazz-, Blues- und Rock-Bands zurückblicken konnten, spielten zwischen 1966 und 1968 eine starke Mischung aus Blues, Rock und Psychedelia, die ihnen Anerkennung seitens der Kritiker und hohe Verkaufszahlen sicherte. Trotz wachsender Erfolge fand die Band neben ihrem rapiden Aufstieg jedoch ein sehr schnelles Ende. 1968, das letzte Jahr der Bandexistenz, war stark von Spannungen zwischen ihren Mitgliedern geprägt, vor allem zwischen Bruce und Baker. Nach einer letzten Tournee durch Amerika sollten die Konzerte in der Londoner Royal Albert Hall den längst geplanten Abschied der Band dokumentieren.
Im Mai 1969 veröffentlichten The Who ihr Album Tommy. Zum ersten Mal in der Rockgeschichte erzählten die 24 Lieder auf vier Plattenseiten eine einzige Geschichte über ein taubes, stummes und blindes Kind, das zum spirituellen Guru wurde. Sofort bekam das Werk, das mit einem "Libretto" verkauft wurde, den pompösen Namen Rock Opera (auch wenn es eher die Bezeichnung Kantate und nicht Oper verdient hätte); kurz nach seiner Veröffentlichung begann die Band, die Lieder des "Tommy" gerufenen Kindes live in den Vereinigten Staaten und England zu präsentieren. Die ersten Aufnahmen von Teilen von Tommy auf einer Bühne datieren aus diesem Sommer, als The Who die Chance hatten, ihre Show auf dem Woodstock-Festival vorzustellen. Ein Jahr später, zum Zeitpunkt der Aufzeichnung des Konzerts auf der Isle of Wight, war die Band somit bereits fast anderthalb Jahre unterwegs auf Tour und hatte sich zu einer der überzeugendsten Live-Acts der Rockgeschichte entwickelt. 1969 hatte die Band schon einmal auf dem Isle-of-Wight-Festival vor damals 100.000 Zuschauern gespielt. Als The Who die Bühne am 30. August 1970 um zwei Uhr morgens betraten, wartete eine 600.000-köpfige Menschenmenge auf sie.
Einleitung: Die allgemeine Häufigkeit der Hernien liegt bei 2 bis 4% der Bevölkerung, wobei etwa 75% Leistenhernien sind. Ziel dieser Studie war die Beschreibung der Morbidität nach standardisierter modifizierter Operation nach Lichtenstein mit Verwendung eines selbsthaftenden Netzes. Der Vergleich dieses Kollektivs mit Daten aus der Literatur, in welchen zur Behandlung einer Leistenhernie die herkömmliche Technik nach Lichtenstein angewandt wurde, stellte das sekundäre Studienziel dar. Material und Methoden: Ein von Juli 2007 bis Dezember 2007 therapiertes Patientengut aus 100 Männern und 11 Frauen des Herz-Jesu-Krankenhauses in Fulda wurde detailliert retrospektiv aufgearbeitet und mit den Ergebnissen anderer Arbeitsgruppen verglichen. Die Patienten wurden einmal nach sechs sowie ein weiteres Mal nach 12 Monaten einbestellt, untersucht und mittels standardisiertem Fragebogen zu ihrem postoperativen Verlauf befragt. Die Altersgrenzen zum Zeitpunkt der operativen Versorgung lagen bei 20 und 91 Jahren, der Altersmedian betrug 59. Die Operation nach Lichtenstein ist eines der bevorzugten Verfahren in der Leistenhernienchirurgie. Ergebnisse: Intraoperativ wurde bei 88 Patienten (79,3 %) der Nervus genitofemoralis geschont, bei 23 Patienten (20,7 %) wurde er durchtrennt. Die postoperativen Komplikationen wurden im eigenen Kollektiv unterteilt nach perioperativen (in den ersten 7 Tagen postoperativ), frühen (7. bis 28. Tag postoperativ) und späten Komplikationen (28. Tag bis 12. Monat postoperativ) erfasst. Nur bei einem Patienten kam es auf Grund eines behandlungspflichtigen Hämatoms zu einer unmittelbaren Komplikation. Kein Patient beklagte eine frühe Komplikation, jedoch kam es bei fünf Patienten zu späten Komplikationen. Vier Patienten klagten über ein Rezidiv. Die Diagnose Nervenkompressionssyndrom wurde bei insgesamt drei Patienten gestellt. Die Verbindung zu einer Durchtrennung des Nervus genitofemoralis konnte bei einem Patienten hergestellt werden. Der Median der Operationsdauer lag bei 35 Minuten. Durchschnitt (Mittelwert) betrug die Krankenhausverweildauer 2,2 Tage. Kein Patient verstarb im postoperativen Verlauf. Schlussfolgerung: Die in dieser Arbeit beschriebene modifizierte Lichtenstein-Technik ist eine Innovation der Hernienchirurgie. Der Einsatz eines teilresorbierbaren und selbstfixierenden Zweikomponenten-Maschengewebe aus monofilem Polypropylen und Polylaktatsäure stellt eine kleine Revolution der operativen Versorgung von Leistenhernien dar. Die ersten Ergebnisse zeigen im Vergleich mit Literaturangaben, dass insgesamt mit einer ähnlichen perioperativen Komplikationsrate zu rechnen ist. Momentan liegen erst Einjahreszahlen vor, daher muss auf eine abschließende Beurteilung, vor allem der postoperativen Schmerzsymptomatik sowie Rezidivrate, zum jetzigen Zeitpunkt verzichtet werden. Erfreulich ist das Fehlen von intraoperativen Komplikationen im eigenen Krankengut. Auch erscheint eine deutliche Reduktion der Operationsdauer bei mit der Technik vertrauten Operateuren möglich zu sein. Eine statistisch signifikante Reduktion der Rezidivhäufigkeit nach Lichtenstein-Eingriff konnte durch die neue Technik noch nicht beobachtet werden. Zur Zeit sind die in der Literatur beschriebenen Rezidivraten noch auf einem ähnlichen Niveau. Abschließend zeigt die Beurteilung der selbst erhobenen Daten und ihr Vergleich mit den angeführten Studien, dass der Einsatz eines selbsthaftenden Netzes bedenkenlos als Alternative zur Fixierung mittels Fibrinkleber, Naht- oder Klammermaterial empfohlen werden kann.
This article discusses the function of tension in autobiographies written by eighteenth-century doctors George Cheyne, Francis Fuller, Claude Revillon, and the Viscount de Puysegur. It studies how their rhetorical strategies stir tensions in readers through the narration of their own periods of infirmity and search for a remedy. The descriptions of their recoveries offer resolution, legitimate their medical practices, and help diffuse their works. Through the staging of these reversals, the authors suggest a shift in the way the role of medical doctors was perceived as well as a fundamental change in their relationship to illness.
Die fragmentierte Verrechtlichung des internationalen Raums, die Proliferation von Regelungsarrangements jenseits des Staates und die Diffusion globaler Normen sowie die daraus resultierenden Geltungs-, Kompetenz- und Autoritätskonflikte sind seit geraumer Zeit ein in der sozialwissenschaftlichen Literatur viel diskutiertes Phänomen. Überlappungen von nationalen Regierungssystemen und von im Völkerrecht verankerten klassischen internationalen Regimen existieren seit der Schaffung des Westfälischen Staatensystems.In jüngerer Zeit verstärkte sich der Pluralismus normativer Ordnungen jedoch global durch neuartige Typen von Regelungsarrangements jenseits des Staates. Auch unter den zwischenstaatlich geschaffenen internationalen Institutionen finden sich solche, die autonome Handlungs- und Entscheidungskompetenzen zugesprochen bekommen haben und diese als Akteure mit eigener Subjektivität ausüben. Hinzu kommt eine immer stärkere Aufnahme von „behind the border issues“ in den Aufgabenkatalog dieser Regime und Organisationen (Zürn 2004). Diese Entwicklungen führen zu einem neuen Grad an Kontestation und Umstrittenheit globaler normativer Ordnungen. Weder die Herstellung einer einheitlichen globalen normativen Ordnung noch eine Re-Nationalisierung des Rechts erscheinen heute als realistische Zukunftsprognosen. Umso wichtiger ist es daher, sich mit den Auswirkungen dieses Pluralismus’ normativer Ordnungen zu beschäftigen.
[Jahresbericht 2010] Katholische Theologie der Johann Wolfgang Goethe-Universität Frankfurt am Main
(2010)
The paper focuses on experience gained at the university of Hildesheim (Germany) where a modular course programme has been introduced which concentrates on less frequently learnt European languages, such as Dutch, Danish, Portuguese and Italian, putting into practice relevant results of research in the field of Contrastive Linguistics. The paper ends with a presentation of the outline of a Turkish reading course for German learners, raising the question to what extent experience gained by comparing and teaching Indo-European languages can be applied to fundamentally different languages like German and Turkish.
Top-down and bottom-up approaches are the general methods used to analyse proteomic samples today, however, the bottom-up approach has been dominant in the last decade. Establishing a bottom-up method involves not only the choice of adequate instruments and the optimisation of the experimental parameters, but also choosing the right experimental conditions and sample preparation steps. LC-ESI MS/MS has widely been used in this field due to its advanced automation. The primary objective of the present study was to establish a sensitive high-throughput nLC-MALDI MS/MS method for the identification and characterisation of proteins in biological samples. The method establishment included optimisation and validation of parameters such as the capillaries in the HPLC systems, gradient slopes, column temperature, spotting frequencies or the MS and MS/MS acquisition methods. The optimisation was performed using two HPLC-systems (Agilent 1100 series and Proxeon Easy nLC system), three spotters and the 4800 MALDI-TOF/TOF analyzer. Furthermore, samples preparation protocols were modified to fit to the established nLCMALDI- TOF/TOF-platform. The potentials of this method was demonstrated by the successful analysis of complex protein samples isolated from lipid particles, pre-adipocytes/adipocytes tissues, membrane proteins and proteins pulled-down from protein-proteins interaction studies. Despite the small amount of proteins in the lipid particles or oil bodies, and the challenges encountered in studying such proteins, 41(6 novel + 14 mammal specific + 21 visceral specific) proteins were added to the already existing proteins of the secretome of human subcutaneous (pre)adipocytes and 6 novel proteins localised in the yeast lipid particles. Protein-protein interaction studies present another area of application. Here the analytical challenges are mostly due to the loss of binding partner upon sample clean-up and to differentiate from non-specific background. Novel interaction partners for AF4•MLL and AF4 protein complex were identified. Furthermore, a novel sample protocol for the analysis of membrane proteins, based on the less specific protease, elastase, was established. Compared to trypsin, a higher sequence coverage and higher coverage of the transmembrane domains were achieved. The use of this enzyme in proteomics has been limited because of its non specific cleavage. However, from the results obtained in these studies, elastase was found to cleave preferentially at the C-terminal site of the amino acids AVLIST. The advantage of the established protocol over conventional protocols is that the same enzyme can be used for shaving of the soluble dormains of intact proteins in membranes and the digestion of the hydrophobic domain after solubilisation. Furthermore, the solvents used are compatible with the nLC-MALDI method setup. In addition, it was also shown that for less specific enzymes, a higher mass accuracy is required to reduce the rate of false positive identifications, since current search engines are not perfectly adapted for these types of enzymes. A brief statistical analysis of the MS/MS data obtained from the LC-MALDI TOF/TOF system showed that for less specific enzymes, under high-energy collision conditions, approximately 43 % of the fragment ions could not be matched to the known y- b type ions and their resultant internal fragments. This limitation greatly influenced the search results. However, this limitation can be overcome by modifying the N-terminal amino acids with basic moieties such as TMT. The use of elastase as a digestion enzyme in proteomic workflow further increased the complexity of the sample. Therefore, orthogonal multidimensional separation was necessary. Offgel-IEF was used as the separation technique for the first dimension. Here peptides are separated according to the pI. However, the acquired samples could not be loaded to the nLC due to the high viscosity of the concentrated samples when using the standard protocol. In order to achieve compatibility of the Offgel-IEF to the nLC-MALDI-TOF/TOF-platform, the separation protocol of the Offgel-IEF was modified by omitting the glycerol, which was the cause of the viscous solution. The novel glycerol free protocol is advantageous over the conventional method because the samples could directly be picked-up and loaded onto the pre-column without resulting in an increase in back pressure or a subsequent pre-column clogging. The glycerol free protocol was then assessed using purple membrane and membrane fraction of C. glutamicum. The results obtained were comparable to those applied in published reports. Therefore, the absence of glycerol did not affect the separation efficiency of the Offgel-IEF. In addition the applicability of elastase and the glycerol free Offgel-IEF for quantitation of membrane proteins was assessed. Most of the unique peptides identified were in the acidic region and 85 % were focused only into one fraction and approximately 95 % in only two fractions. These results are in accordance with previously published results (Lengqvist et al., 2007). When compared with theoretical digests of the proteins identified in this study, it can be concluded that basic moiety (TMT) on the peptide backbone, did not affect the separation efficiency of the Offgel-IEF. In an applied study, changes in the protein content of yeast strain grown in two different media were relatively quantified. For example, prominent proteins, such as the hexose tranporter proteins responsible for transporting glucose accross the membrane, were successfully quantified. Last but not least, the nLC-MALDI-TOF/TOF platform also served as a basis for the development of a high-throughput method for the identification of protein phosphorylation. The establishment of such a method using MALDI has been challenging due to the lack of sensitive matrices, such as CHCA for non-modified peptides, which exhibit a homogenous crystallisation and thus yield stable signal intensity over a long period of time in an automated setup. The first step of this method was the establishment of a matrix/matrix mixture with better crystal morphology and higher analyte signal intensity than the matrix of choice, i.e. DHB. From MS and MS/MS measurements of standard phosphopeptides, a combination of FCCA and CHAC in a 3:1 ratio and 3 mM NH4H2PO4 facilitated high analyte signal intensities and good fragmentation behaviour. Combining a custom-packed biphasic column for the enrichment of phosphopeptides, the applicability of the matrix mixture was assessed in anautomated phosphopeptide analysis using standard phosphopeptides spiked to a 20-fold excess BSA digest. These analyses showed that this method is reproducibile and both flow throughs can be analysed. Applying the method to the analysis of 2 standard phosphoproteins, alpha/beta-casein, and a leukemia related protein, ENL, 13 phosphopeptides from both alpha/beta-Casein and 13 phosphopeptides with 6 phosphorylation sites from the ENL were identified. As a general conclusion, it can be stated that the nLC-MALDI-TOF/TOF method established here in various modifications for different analytical purposes is a robust platform for proteomic analyses.
Das Verhältnis zwischen Gott und Mensch wird sowohl im katholischen Christentum als auch im Islam durch das fehlerhafte Verhalten des Menschen beeinträchtigt und verletzt. Basierend auf das jeweilige Schuldverständnis wurde in beiden Religionen der Weg der (Wieder-) Versöhnung mit Gott theologisch aufbereitet und dargestellt. Diese Theologien führen auf ihre jeweils eigene Art wieder zu Gott und ermöglichen seine Freundschaft, was für den sündhaften Gläubigen Hoffnung und Zuversicht beinhaltet und seine existentielle Sorge um seine Seele nimmt. Auf diese Weise bietet der jeweilige Glaube sowohl dem Katholiken als auch dem Muslim seelsorgerlichen Halt und Trost und lässt ihn auf ein glückliches Ende hoffen.
In the olden days, after a day's work in the farms, children and parents returned home feeling worn out. As a sort of evening entertainment, children of the same family, compound or village then gathered round a story-teller to listen to folk tales and riddles. This was common in every African home. The listeners participate with joy by joining in the songs and choruses. Sometimes the children were given the opportunity to tell stories that they had known while the adult story-teller listened attentively in order to add more details where necessary. In telling these stories and riddles, children were expected to learn something through all those activities connected with the customs, environment, language and religious practices of their people. This book provides children with stories, riddles and some proverbs that parents ought to have told their children at home but have failed because of their present day busy schedules. Teachers will fill that vacuum at school as they guide the children in reading the stories, riddles and proverbs in their second language-English. As an instructional tool, this collection will foster literacy, promote cultural awareness and create situations where learners share with one another their personal experiences and traditions.
A Basket of Flaming Ashes
(2010)
Ashuntantang is an extraordinary weaver of words who showcases vivid pictures that compete with 3D simulation. Her greatest asset is her use of the beautiful traditional Cameroonian anchor that evokes folk tales with its moonlight romance and glory. You feel, laugh, weep, shiver, wonder, and hail the triumphant spirit of the persona as it navigates African postcolonial and global experiences with the melancholy of an exile who is purposeful, strategic, and a lot of fun.
The personality of the highly charismatic foremost African Nationalist, Kwame Nkrumah as featured once in a while in Ghanaian fiction. For example, the celebrated Ghanaian novelist, Ayi Kwei Armah draws attention to the corrupt nature of the Nkrumah regime in his famous novel, The Beautyful Ones Are Not Yet Born. But this is by far the very first time that Kwame Nkrumah and his era have been made the main subject of a full-length novel.
Chopchair
(2010)
The extremely irritable and quick-tempered chieftain, Akendong II has 14 children, all girls, and is saddened by the fact that he has no chopchair, a male heir to his throne. Then news comes to him that his favourite wife has given birth to a pair of twins, boys. He is even more angered by the fact that he has two heirs, a source of trouble for his kingdom. To avoid his wrath, his councillors change the story, sending away one of the boys to grow in hiding. Learning of the truth about his birth 15 years afterwards, the prince in hiding returns, kidnaps the palace prince and demands his full share of the kingdom. His will is done, but at a very great cost to the chief's peace of mind and relationship with his people. This is by far the shortest of Asong's novels and the least complicated by comparison. But the conflicts, the hallmarks of his art are still there, so also is his breathtaking suspense.
Stranger in his Homeland
(2010)
Stranger in His Homeland completes the long-awaited trilogy of Linus Asong's fictitious village of Nkokonoko Small Monje, separately treated in The Crown of Thorns and its sequel A Legend of the Dead. However, it leads us back not to events after A Legend of the Dead, but to the crisis that created the passionately exciting The Crown of Thorns. Honest, enthusiastic, arrogant and self-righteous, Antony Nkoaleck, the first graduate of his tribe means well. But his society, entrenched in corruption, sees things differently and therefore judges him according to its own norms. Just one or two errors on Antony's part are enough to cost him his job with the government, the coveted throne of Nkokonoko Small Monje, and finally his life. It is a sad story, strongly reminiscent of Myshkin's fate in Dostoevysky's novel The Idiot, a story in which the Russian novelist vividly shows the inability of any man to bear the burden of moral perfection in an imperfect world.
Doctor Frederick Ngenito
(2010)
Dr. Frederick Ngenito shocks his entire ethnic community by finally marrying a girl whose rejection of him had cost him an enviable job. But this is nothing compared to the ire of the ancestors when he hides the facts surrounding his irate father's suicide and he is buried without the traditional cleansing, and which reduces him to a wreck. Harrowing but thoroughly enjoyable, this spellbinder of a novel is a brash standoff between filia and eros, science and fetish fears. Bloodcurdling premonitions and raspy raw effects make of this novel of many parts a story of dogged intolerance and catastrophe of half measures and falsification as quick solutions. Here is an unputdownable teeming with vivid true blood characters you cannot forget: Fred, brilliant, handsome, nai͏̈vely supercilious, the dream of every beautiful young girl; Beatrice, his wife, beautiful, proud, sensitive but unforgiving; Chief Mutare, Fred's father, the very incarnation of brute force, raw, untouched either by surface culture or inner human feelings. Upon the fatalistic relationship between these three characters, Asong builds this grim tale of great passions, of a love that is doomed. In this book stamped with an incomparable aura of authenticity, we see why Asong's novels are sometimes mistaken for case histories.
The Crabs of Bangui
(2010)
Every man lives for himself, using his freedoms to attain his personal aims, and feels with his whole being that he can at any moment perform or not perform this or that action. The higher a man stands in the social scale, the more connections he has with others and the more power he has over them, the more conspicuous is the predestination and inevitability of every act he commits. Upon this philosophy, a former banker, Hansel Bolingo, suddenly finds [or makes] himself the regional representative of a Chinese firm that deals in crabs in Bangui. This catapults him into a position of instant wealth. His mouth-watering affluence draws immediate attention while his hypnotic powers cause hundreds of [not-so-honest]citizens to clamour for shares from which he builds up a huge fortune. But he soon discovers that he cannot deceive everybody all the time.
Laughing Store is just what we need in times of troubles and uncertainties such as these. A book of humour from an acclaimed master of laughter, it lifts our hearts and raises our spirits. Jokes that touch about every domain of existence - from sex to religion, from births to deaths, from politics to the beer parlour, from the courtroom to the hospital. And most important of all, conceived in the supremely original Cameroonian flavour of jokes.
Child of earth
(2010)
Child of Earth is the story of Achu, a young African boy who loses his mother when he is still a baby. He is raised by his father in a household teeming with wives and children. Then the father dies and the task of raising Achu devolves on his aunt, his father's sister, who is married to one of the richest and most powerful men in the country. But the aunt is jealous because Achu is doing better in school than her own children . . .