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Master of science in international economics and economic policy : guidelines winter term 2017/2018
(2017)
One striking observation in Parkinson’s disease (PD) is the remarkable gender difference in incidence and prevalence of the disease. Data on gender differences with regard to disease onset, motor and non-motor symptoms, and dopaminergic medication are limited. Furthermore, whether estrogen status affects disease onset and progression of PD is controversially discussed. In this retrospective single center study, we extracted clinical data of 226 ambulatory PD patients and compared age of disease onset, disease stage, motor impairment, non-motor symptoms, and dopaminergic medication between genders. We applied a matched-pairs design to adjust for age and disease duration. To determine the effect of estrogen-related reproductive factors including number of children, age at menarche, and menopause on the age of onset, we applied a standardized questionnaire and performed a regression analysis. The male to female ratio in the present PD cohort was 1.9:1 (147 men vs. 79 women). Male patients showed increased motor impairment than female patients. The levodopa equivalent daily dose was increased by 18.9% in male patients compared to female patients. Matched-pairs analysis confirmed the increased dose of dopaminergic medication in male patients. No differences were observed in age of onset, type of medication, and non-motor symptoms between both groups. Female reproductive factors including number of children, age at menarche, and age at menopause were positively associated with a delay of disease onset up to 30 months. The disease-modifying role of estrogen-related outcome measures warrants further clinical and experimental studies targeting gender differences, specifically hormone-dependent pathways in PD.
Nach den Ereignissen in Gaggenau liest und hört man allenthalben von den "rechtlichen Schwierigkeiten", die hinsichtlich Verboten von Redeauftritten ausländischer Politiker bestünden. In Gaggenau hat man originär sicherheitsrechtlich argumentiert: viel zu viele Leute, viel zu kleiner Parkplatz, Chaos vorprogrammiert. Ähnliches nun in Köln: zu großer Aufwand, zu kurzfristig, Chaos vorprogrammiert. Nehmen wir einmal an, es seien im Einzelfall tragfähige Begründungen gewesen. Dann stellt sich zugleich die Frage: Was kann man tun, wenn man den Auftritt eines ausländischen Vertreters untersagen will, obwohl der Parkplatz groß genug und die Polizei ausreichend gegen Ausschreitungen gewappnet ist? ...
Risk culture during the last 2000 years - from an aleatory society to the illusion of risk control
(2017)
The culture of risk is 2000 years old, although the term “risk” developed much later. The culture of merchants making decisions under uncertainty and taking the individual responsibility for the uncertain future started with the Roman “Aleatory Society”, continued with medieval sea merchants, who made business “ad risicum et fortunam”, and sustained to the culture of entrepreneurs in times of industrialisation and dynamic economic changes in the 18th and 19th century. For all long-term commercial relationships, the culture of honourable merchants with personal decision-making and individual responsibility worked well. The successful development of sciences, statistics and engineering within the last 100 years led to the conjecture that men can “construct” an economical system with a pre-defined “clockwork” behaviour. Since probability distributions could be calculated ex-post, an illusion to control risk ex-ante became a pattern in business and banking. Based on the recent experiences with the financial crisis, a “risk culture” should understand that human “Strength of Knowledge” is limited and the “unknown unknown” can materialise. As all decisions and all commercial agreements are made under uncertainty, the culture of honourable merchants is key to achieve trust in long-term economic relations with individual responsibility, flexibility to adapt and resilience against the unknown.
WiWi news [2/2017]
(2017)
Why MREL won’t help much
(2017)
Missed opportunity
(2017)
Expectations on others
(2017)
SME funding without banks?
(2017)
Litmus test Monte Paschi
(2017)
The euro is not at risk
(2017)
Banks must save even more
(2017)
Vergebene Chance
(2017)
Stimmzettel als Denkzettel
(2017)
Lackmustest Monte Paschi
(2017)
Euro nicht gefährdet
(2017)
Jan Pieter Krahnen empfiehlt in Börsenzeitung eine zentrale europäische Aufsicht.
Würde der Zusammenbruch einiger Clearinghäuser die Stabilität des Finanzsystems gefährden? Und wie lässt sich Europas fragmentierter Clearingmarkt regulieren? Diese Fragen werden in Politik und Wissenschaft kontrovers diskutiert.
Jan Pieter Krahnen, Direktor des Forschungszentrums SAFE und Professor für Finanzen an der Goethe-Universität Frankfurt, fordert in der Börsenzeitung vom 1. Februar eine zentrale europäische Aufsicht für den fragmentierten europäischen Clearingmarkt. Eine gemeinsame Überwachungsinstanz könne die Gesamtmarktlage überblicken und eingreifen, wenn die Systemstabilität gefährdet sei...