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The dynamics of strange pseudoscalar and vector mesons in hot and dense nuclear matter is studied within a chiral unitary framework in coupled channels. Our results set up the starting point for implementations in microscopic transport approaches of heavy-ion collisions, particularly at the conditions of the forthcoming experiments at GSI/FAIR and NICA-Dubna. In the K̄ N sector we focus on the calculation of (off-shell) transition rates for the most relevant binary reactions involved in strangeness production close to threshold energies, with special attention to the excitation of sub-threshold hyperon resonances and isospin effects (e.g. K̄ p vs K̄ n). We also give an overview of recent theoretical developments regarding the dynamics of strange vector mesons (K*, K̄* and ϕ) in the nuclear medium, in connection with experimental activity from heavy-ion collisions and nuclear production reactions. We emphasize the role of hadronic decay modes and the excitation of hyperon resonances as the driving mechanisms modifying the properties of vector mesons.