Refine
Document Type
- Working Paper (2)
- Article (1)
Language
- English (3)
Has Fulltext
- yes (3)
Is part of the Bibliography
- no (3)
Keywords
- 3D printed cell-free scaffold (1)
- Conflict Factors (1)
- Conflict Prevention (1)
- Conflict Prolonging Factors (1)
- Côte d’Ivoire (1)
- Escalation Patterns (1)
- Ghana (1)
- Peace Order (1)
- Root causes (1)
- Sub-Saharan Africa (1)
Institute
- Medizin (1)
Football coverage in newspapers is both an arena for and a mirror of political discourse within a society. The paper argues that discourses within football coverage referring to political issues reflect dominant – and, possibly, contesting – “truths”, which themselves are linked to power relations and political struggles within a given society. The comparison of Côte d’Ivoire and Ghana, two neighbouring countries in very different conditions (particularly with regard to their historical trajectories and the degree of societal consensus), and more particularly, the comparison of dominant discourses on the topics of patriotism, peace and good governance related to the World Cup qualification of both national teams supports the hypothesis of a strong context-relatedness of a politically loaded “football language”. For instance, whereas in Ghana patriotism is, when football comes in, quickly merged with pan-africanism, the Ivorian team renewed the heated political debate about “Ivorianess” by putting forward a notion of inclusive patriotism.
Current thinking on African conflicts suffers from misinterpretations oversimplification, lack of focus, lack of conceptual clarity, state-centrism and lack of vision). The paper analyses a variety of the dominant explanations of major international actors and donors, showing how these frequently do not distinguish with sufficient clarity between the ‘root causes’ of a conflict, its aggravating factors and its triggers. Specifically, a correct assessment of conflict prolonging (or sustaining) factors is of vital importance in Africa’s lingering confrontations. Broader approaches (e.g. “structural stability”) offer a better analytical framework than familiar one-dimensional explanations. Moreover, for explaining and dealing with violent conflicts a shift of attention from the nation-state towards the local and sub-regional level is needed.
Biofabrication of SDF-1 functionalized 3D-printed cell-free scaffolds for bone tissue regeneration
(2020)
Large segmental bone defects occurring after trauma, bone tumors, infections or revision surgeries are a challenge for surgeons. The aim of our study was to develop a new biomaterial utilizing simple and cheap 3D-printing techniques. A porous polylactide (PLA) cylinder was printed and functionalized with stromal-derived factor 1 (SDF-1) or bone morphogenetic protein 7 (BMP-7) immobilized in collagen type I. Biomechanical testing proved biomechanical stability and the scaffolds were implanted into a 6 mm critical size defect in rat femur. Bone growth was observed via x-ray and after 8 weeks, bone regeneration was analyzed with µCT and histological staining methods. Development of non-unions was detected in the control group with no implant. Implantation of PLA cylinder alone resulted in a slight but not significant osteoconductive effect, which was more pronounced in the group where the PLA cylinder was loaded with collagen type I. Addition of SDF-1 resulted in an osteoinductive effect, with stronger new bone formation. BMP-7 treatment showed the most distinct effect on bone regeneration. However, histological analyses revealed that newly formed bone in the BMP-7 group displayed a holey structure. Our results confirm the osteoinductive character of this 3D-biofabricated cell-free new biomaterial and raise new options for its application in bone tissue regeneration.