Refine
Year of publication
Document Type
- Preprint (579)
- Article (370)
- Working Paper (3)
- Conference Proceeding (2)
- Part of a Book (1)
Language
- English (955) (remove)
Has Fulltext
- yes (955) (remove)
Is part of the Bibliography
- no (955)
Keywords
- Heavy Ion Experiments (18)
- Hadron-Hadron scattering (experiments) (11)
- Heavy-ion collision (6)
- LHC (6)
- Kollisionen schwerer Ionen (5)
- Hadron-Hadron Scattering (4)
- Quark-Gluon Plasma (4)
- heavy ion collisions (4)
- ALICE experiment (3)
- Heavy Ions (3)
- Jets and Jet Substructure (3)
- Quark Gluon Plasma (3)
- Accelerators & Beams (2)
- Atomic, Molecular & Optical (2)
- Beauty production (2)
- Charm physics (2)
- Experimental nuclear physics (2)
- Experimental particle physics (2)
- Fragmentation (2)
- Jets (2)
- Lepton-Nucleon Scattering (experiments) (2)
- Particle and resonance production (2)
- Particle correlations and fluctuations (2)
- Pb–Pb collisions (2)
- Psychiatric disorders (2)
- QGP (2)
- Quark-Gluon-Plasma (2)
- RNA interference (RNAi) (2)
- Single electrons (2)
- UrQMD Modell (2)
- peptide aptamer (PA) (2)
- pp collisions (2)
- quark-gluon-plasma (2)
- signal transducer and activator of transcription 5 (Stat5) (2)
- 16S rRNA sequencing (1)
- ADAMTS-13 (1)
- ADHD (1)
- ALICE (1)
- ALICE detector (1)
- AO-PCCF (1)
- ATR-FTIR (1)
- Abundance (1)
- Accelerators & storage rings (1)
- Acute coronary syndrome (1)
- Anemia (1)
- Anonymity (1)
- Anti-kaon–nucleon physics (1)
- Anti-nuclei (1)
- Anticoagulation (1)
- Aortic valve (1)
- Aortic valve replacement (1)
- Atomic & molecular beams (1)
- Atomic and Molecular Physics (1)
- Atrial fibrillation (1)
- Autecology (1)
- Bcr-Abl (1)
- Beam loss (1)
- Biofuel (1)
- Bleeding (1)
- Blood loss (1)
- Blood transfusion (1)
- Breast cancer (1)
- Butanol (1)
- COVID-19 (1)
- Cardiac troponin (1)
- Centrality Class (1)
- Centrality Selection (1)
- Charge-transfer collisions (1)
- Circular accelerators (1)
- Clinical Trials and Observations (1)
- Clinical genetics (1)
- Collective Flow (1)
- Competition (1)
- DTI (1)
- Dark Trading (1)
- Difficult Airway Management (1)
- Ehrlich pathway (1)
- Electron-pion identification (1)
- Electronic transitions (1)
- Electroweak interaction (1)
- Elliptic flow (1)
- Energie (1)
- Epilepsy (1)
- Equation of state (1)
- Exosomes (1)
- Experimental autoimmune encephalomyelitis (1)
- Feeding types (1)
- Fermentation (1)
- Fibre/foam sandwich radiator (1)
- Freshwater (1)
- Genetic engineering (1)
- HER2-positive (1)
- Hadron-Hadron Scattering Heavy (1)
- Hadron-hadron interactions (1)
- Heavy Ion Experiment (1)
- Heavy Quark Production (1)
- Heavy flavor production (1)
- Heavy ion collisions (1)
- Heavy ion storage ring (1)
- Heavy ions (1)
- Heavy-flavour decay muons (1)
- Heavy-flavour production (1)
- Hemostasis (1)
- Human behaviour (1)
- INR (1)
- Immediacy (1)
- In-Hospital Emergencies (1)
- Inflammation (1)
- International normalized ratio (1)
- Invariant Mass Distribution (1)
- Ionisation energy loss (1)
- Isobutanol (1)
- J/ϕ (1)
- Jak2(V617F) (1)
- Kaonic nuclei (1)
- Laryngeal Tube (1)
- Liquidity (1)
- Local thermodynamical equilibrium (1)
- Low & intermediate-energy accelerators (1)
- Low energy QCD (1)
- Lymphoid Neoplasia (1)
- Market Quality (1)
- Market Structure (1)
- Mice (1)
- MicroRNAs (1)
- Microplastic-biota interaction (1)
- Mid-rapidity (1)
- Minimum Bias (1)
- Molecular neuroscience (1)
- Monte Carlo (1)
- Monte-Carlo model for relativistic heavy ion collisions (1)
- Multi-strange baryons (1)
- Multi-wire proportional drift chamber (1)
- Myocardial infarction (1)
- NMR spectroscopy (1)
- Neoadjuvant therapy (1)
- Neonatal brain damage (1)
- Neural circuits (1)
- Neural network (1)
- Nichtgleichgewicht (1)
- Non-equilibrium effects (1)
- Orbital electron capture (1)
- Partial wave analysis (1)
- Particle Correlations and Fluctuations (1)
- Pathological complete response (1)
- Patient blood management (1)
- Personalized medicine (1)
- Photon counting (1)
- Plastic polymers (1)
- Point-of-care testing (1)
- Polarization (1)
- Polymers (1)
- Predictive markers (1)
- Preference for early resolution of uncertainty (1)
- Production Cross Section (1)
- Properties of Hadrons (1)
- Proton–proton (1)
- Pyrolysis GC–MS (1)
- QCD (1)
- QGP signals (1)
- QMD Modell (1)
- QMD model (1)
- Quark Production (1)
- Quark gluon plasma (1)
- Radiation detectors (1)
- Rapidity Range (1)
- Relativistic heavy ion physics (1)
- Relativistic heavy-ion collisions (1)
- Resolution Parameter (1)
- SARS-CoV-2 (1)
- SPS (1)
- Saccharomyces (1)
- Single particle decay spectroscopy (1)
- Statistical model (1)
- Supraglottic Airway Devices (1)
- Suspended solids (1)
- Systematic Uncertainty (1)
- TBSS (1)
- TR (1)
- Time Projection Chamber (1)
- Tracking (1)
- Transcatheter based aortic valve implantation (1)
- Transition radiation detector (1)
- Trigger (1)
- Triple negative (1)
- Two body weak decay (1)
- URQMD (1)
- Ultra-relativistic Quantum Molecular Dynamics model (1)
- Ultrarelativistic Quantum Molecular Dynamics (1)
- Ultrarelativistic Quantum Molecular Model (1)
- Ultrarelativistisches Quant Molekulares Modell (1)
- UrQMD model (1)
- Valine biosynthesis (1)
- Vector (1)
- Vector Boson Production (1)
- Visual analysis (1)
- Xenon-based gas mixture (1)
- Yeast (1)
- Zustandsgleichung (1)
- accessory proteins (1)
- antibodies (1)
- asparaginyl endopepdidase (AEP) (1)
- asset pricing (1)
- attention (1)
- b-cell lymphomas (1)
- bendamustine (1)
- canonical/non-canonical (1)
- cardiac surgery (1)
- cardiovascular pharmacology (1)
- cell-free protein synthesis (1)
- chemokines (1)
- chemotherapy regimen (1)
- chimeric antigen receptor t-cell therapy (1)
- chimeric antigen receptors (1)
- chronic hypoxia (1)
- chronic myeloid leukemia (CML) (1)
- cross-section of expected stock returns (1)
- dE/dx (1)
- development (1)
- dileptons (1)
- ectosomes (1)
- energy (1)
- equation of state (1)
- exosomes (1)
- extracellular vesicles (1)
- flow (1)
- functional magnetic resonance imaging (fMRI) (1)
- glycolysis (1)
- guidelines (1)
- hadron hadron Kollision (1)
- hadron hadron collision (1)
- heart failure (1)
- heavy ion experiments (1)
- heavy ions (1)
- hematopoietic stem cell transplantation (1)
- hemispherotomy (1)
- human erythroid leukemia (HEL) (1)
- humoral factors (1)
- hyperactivity (1)
- hypoparathyroidism (1)
- implied volatility (1)
- impulsivity (1)
- indication (1)
- inhibition of DNA-binding (1)
- interleukin-6 (1)
- intrinsically disordered region (1)
- juvenile brain lesion (1)
- legumain (1)
- leukapheresis (1)
- lokales thermodynamisches Gleichgewicht (1)
- lower leg fracture (1)
- lymphoma (1)
- microbiome (1)
- microparticles (1)
- microvesicles (1)
- minimal information requirements (1)
- molecular mechanisms (1)
- multiple myeloma (1)
- multiple sclerosis (1)
- nonstructural proteins (1)
- object tracking (1)
- pancreatic cancer (1)
- pancreatic surgery (1)
- particle ratios (1)
- plasticity (1)
- polygenic risk score (1)
- postoperative complications (1)
- ppK − (1)
- propofol anesthesia (1)
- prostate and breast cancer cell lines (1)
- protein transduction (1)
- protein/lentiviral transduction (1)
- quark gluon plasma (1)
- recurrent laryngeal nerve palsy (1)
- registry (1)
- relativistic (1)
- relativistische (1)
- remodelling (1)
- remote ischemic preconditioning (1)
- reproducibility (1)
- rigor (1)
- rituximab (1)
- schwere Ione (1)
- selective attention (1)
- spectra (1)
- standardization (1)
- strangeness (1)
- structural proteins (1)
- substance abuse disorder (1)
- therapy (1)
- thermalization (1)
- thrombotic microangiopathy (1)
- thrombotic thrombocytopenic purpura (1)
- thyroid resection (1)
- tibial fracture (1)
- toddler’s fracture (1)
- vascular surgery (1)
- venturesomeness (1)
- visuo-spatial attention (1)
- von Willebrand factor (1)
- x-ray techniques (1)
- yeast-two-hybrid (Y2H) (1)
Institute
- Physik (909)
- Frankfurt Institute for Advanced Studies (FIAS) (811)
- Informatik (775)
- Medizin (33)
- Center for Financial Studies (CFS) (3)
- ELEMENTS (3)
- Hochschulrechenzentrum (3)
- Informatik und Mathematik (3)
- Wirtschaftswissenschaften (3)
- Biowissenschaften (2)
The radiative electron capture (REC) into the K shell of bare Xe ions colliding with a hydrogen gas target has been investigated. In this study, the degree of linear polarization of the K-REC radiation was measured and compared with rigorous relativistic calculations as well as with the previous results recorded for U92+. Owing to the improved detector technology, a significant gain in precision of the present polarization measurement is achieved compared to the previously published results. The obtained data confirms that for medium-Z ions such as Xe, the REC process is a source of highly polarized x rays which can easily be tuned with respect to the degree of linear polarization and the photon energy. We argue, in particular, that for relatively low energies the photons emitted under large angles are almost fully linear polarized.
A wide variety of enzymatic pathways that produce specialized metabolites in bacteria, fungi and plants are known to be encoded in biosynthetic gene clusters. Information about these clusters, pathways and metabolites is currently dispersed throughout the literature, making it difficult to exploit. To facilitate consistent and systematic deposition and retrieval of data on biosynthetic gene clusters, we propose the Minimum Information about a Biosynthetic Gene cluster (MIBiG) data standard.
A central motivation for the development of x-ray free-electron lasers has been the prospect of time-resolved single-molecule imaging with atomic resolution. Here, we show that x-ray photoelectron diffraction—where a photoelectron emitted after x-ray absorption illuminates the molecular structure from within—can be used to image the increase of the internuclear distance during the x-ray-induced fragmentation of an O2 molecule. By measuring the molecular-frame photoelectron emission patterns for a two-photon sequential K-shell ionization in coincidence with the fragment ions, and by sorting the data as a function of the measured kinetic energy release, we can resolve the elongation of the molecular bond by approximately 1.2 a.u. within the duration of the x-ray pulse. The experiment paves the road toward time-resolved pump-probe photoelectron diffraction imaging at high-repetition-rate x-ray free-electron lasers.
The electron-capture process was studied for Xe54+ colliding with H2 molecules at the internal gas target of the Experimental Storage Ring (ESR) at GSI, Darmstadt. Cross-section values for electron capture into excited projectile states were deduced from the observed emission cross section of Lyman radiation, being emitted by the hydrogenlike ions subsequent to the capture of a target electron. The ion beam energy range was varied between 5.5 and 30.9 MeV/u by applying the deceleration mode of the ESR. Thus, electron-capture data were recorded at the intermediate and, in particular, the low-collision-energy regime, well below the beam energy necessary to produce bare xenon ions. The obtained data are found to be in reasonable qualitative agreement with theoretical approaches, while a commonly applied empirical formula significantly overestimates the experimental findings.
Background and Objectives: Proteins of the coagulation system contribute to autoimmune inflammation in patients with multiple sclerosis (MS). On blood-brain barrier (BBB) disruption, fibrinogen enters the CNS and is rapidly converted to fibrin, unfolding pleiotropic autoimmune mechanisms. Fibrin accumulation leads to subsequent proteolytic degradation that results in D-dimer generation. The primary objective of this study was to determine intrathecal levels of D-dimer in CSF as a measure of intrathecal coagulation cascade activation and to evaluate its diagnostic utility in patients with MS in contrast to healthy subjects. Key secondary objectives included analysis of CSF D-dimer in differential diagnoses of MS and its relation to routine clinical markers of disease activity.
Methods: Patients admitted for the assessment of suspected MS were prospectively recruited from October 2017 to December 2020. Blood plasma and citrated CSF samples were analyzed using a highly sensitive luminescent oxygen channeling immunoassay. Intrathecal generation of D-dimer was analyzed by adjusting for CSF/serum albumin (Qalb) and CSF/plasma D-dimer quotients (QD-dimer), and corresponding CSF fibrinogen levels were determined. Final diagnoses after full evaluation and clinical data were recorded.
Results: Of 187 patients, 113 patients received a diagnosis of MS or clinically/radiologically isolated syndrome. We found increased intrathecal CSF D-dimer generation levels (QD-dimer/Qalb-index) for patients with relapsing-remitting MS (RRMS; n = 71, median 4.7, interquartile range [IQR] 2.5–8.0) when compared with those for disease controls (n = 22, median 2.6, IQR 2.1–4.8, p = 0.031). Absolute CSF D-dimer values correlated with CSF fibrinogen levels (r = 0.463; p < 0 .001) and CSF leukocytes (r = 0.273; p = 0.003) and were elevated in MS patients with contrast enhancement (CE) compared with MS patients without CE on MRI (n = 48, median 6 ng/mL, and IQR 3–15.25 vs n = 41, median 4 ng/mL, and IQR 2–7; p = 0.026). Exploratory subgroup analyses indicated a correlation of intrathecal inflammatory activity and CSF D-dimer levels.
Discussion: D-dimer in CSF can be reliably determined and correlates with markers of CNS inflammation and CSF fibrinogen levels. Adjusted for BBB dysfunction, CSF D-dimer may allow the identification of intrathecal coagulation cascade activation in patients with MS.
Classification of Evidence: This study provides Class I evidence that CSF D-dimer levels are elevated in patients with RRMS.