Refine
Year of publication
Language
- English (231)
Has Fulltext
- yes (231)
Is part of the Bibliography
- no (231)
Keywords
- BESIII (16)
- e +-e − Experiments (10)
- Branching fraction (8)
- Hadronic decays (5)
- Branching fractions (4)
- Lepton colliders (4)
- Particle and Resonance Production (4)
- Quarkonium (4)
- Charm Physics (3)
- Charmed mesons (3)
- Electroweak interaction (3)
- Exotics (3)
- Initial state radiation (3)
- Spectroscopy (3)
- e+-e− Experiments (3)
- Bhabha (2)
- Biosynthetic mesh (2)
- Charm physics (2)
- Charmonium (2)
- Cross section (2)
- Electroweak Interaction (2)
- Hadronic cross section (2)
- Incisional hernia (2)
- Leptonic, semileptonic & radiative decays (2)
- Muon anomaly (2)
- Particle decays (2)
- Pion form factor (2)
- QCD (2)
- Absolute branching fraction (1)
- Angular distribution (1)
- Annihilation (1)
- BESIII detector (1)
- Born cross section measurement (1)
- CP violation (1)
- Charmonium (-like) (1)
- Complex hernia (1)
- Complications (1)
- Covariance matrix (1)
- Cross section measurements (1)
- D meson (1)
- D0 and D+ mesons (1)
- Dalitz decay (1)
- Dark photon (1)
- Dark sector (1)
- D⁰ meson (1)
- Electromagnetic amplitude (1)
- Electromagnetic form factor (1)
- Electromagnetic form factors (1)
- Experimental nuclear physics (1)
- Experimental particle physics (1)
- FOS: Physical sciences (1)
- Flavor changing neutral currents (1)
- Flavor symmetries (1)
- Flavour Physics (1)
- Form factors (1)
- Hadronization (1)
- Hadrons (1)
- Heavy ion collisions (1)
- Hernia recurrence (1)
- Hernia surgery (1)
- High Energy Physics - Experiment (hep-ex) (1)
- Hyperons (1)
- Inclusive branching fraction (1)
- Invisible decays (1)
- K0S (1)
- Mesh repair (1)
- Midline laparotomy (1)
- Net-charge correlations (1)
- Net-charge fluctuations (1)
- Neutrinos (1)
- Particle and resonance production (1)
- Particle phenomena (1)
- Phase (1)
- Polarization (1)
- Proton (1)
- Quantum chromodynamics (1)
- R value (1)
- Rare decays (1)
- Semi-leptonic decays (1)
- Strong amplitude (1)
- Surgical site occurrence (1)
- Techniques Electromagnetic calorimeters (1)
- Triple quarkonia (1)
- W-exchange (1)
- Y (4260) (1)
- Y states (1)
- branching fractions (1)
- center-of-mass energy (1)
- charmed baryon (1)
- charmonium-like states (1)
- decay (1)
- decays (1)
- dimuon (1)
- diphoton (1)
- e+e − annihilation (1)
- e+e⁻ − Experiments (1)
- e+e− annihilation (1)
- electron-positron collision (1)
- hadron spectroscopy (1)
- hadronic events (1)
- helicity amplitude analysis (1)
- inclusive J/ψ decays (1)
- luminosity (1)
- number of J/ψ events (1)
- tetraquark (1)
- trigger efficiency (1)
- Λ+c baryon (1)
- Λc⁺ (1)
- Σ hyperon (1)
- ψ(3686) (1)
Institute
- Physik (225)
- Medizin (3)
- Frankfurt Institute for Advanced Studies (FIAS) (2)
Introduction: Information on the long-term performance of biosynthetic meshes is scarce. This study analyses the performance of biosynthetic mesh (Phasix™) over 24 months.
Methods: A prospective, international European multi-center trial is described. Adult patients with a Ventral Hernia Working Group (VHWG) grade 3 incisional hernia larger than 10 cm2, scheduled for elective repair, were included. Biosynthetic mesh was placed in sublay position. Short-term outcomes included 3-month surgical site occurrences (SSO), and long-term outcomes comprised hernia recurrence, reoperation, and quality of life assessments until 24 months.
Results: Eighty-four patients were treated with biosynthetic mesh. Twenty-two patients (26.2%) developed 34 SSOs, of which 32 occurred within 3 months (primary endpoint). Eight patients (11.0%) developed a hernia recurrence. In 13 patients (15.5%), 14 reoperations took place, of which 6 were performed for hernia recurrence (42.9%), 3 for mesh infection (21.4%), and in 7 of which the mesh was explanted (50%). Compared to baseline, quality of life outcomes showed no significant difference after 24 months. Despite theoretical resorption, 10.7% of patients reported presence of mesh sensation in daily life 24 months after surgery.
Conclusion: After 2 years of follow-up, hernia repair with biosynthetic mesh shows manageable SSO rates and favorable recurrence rates in VHWG grade 3 patients. No statistically significant improvement in quality of life or reduction of pain was observed. Few patients report lasting presence of mesh sensation. Results of biosynthetic mesh after longer periods of follow-up on recurrences and remodeling will provide further valuable information to make clear recommendations.
Trial registration: Registered on clinicaltrials.gov (NCT02720042), March 25, 2016.