Refine
Year of publication
Language
- English (771)
Has Fulltext
- yes (771)
Is part of the Bibliography
- no (771)
Keywords
- Heavy Ion Experiments (20)
- Hadron-Hadron scattering (experiments) (11)
- Hadron-Hadron Scattering (8)
- Heavy-ion collision (5)
- Collective Flow (4)
- Quark-Gluon Plasma (4)
- Jets (3)
- Jets and Jet Substructure (3)
- Experimental nuclear physics (2)
- Experimental particle physics (2)
- Heavy Quark Production (2)
- Lepton-Nucleon Scattering (experiments) (2)
- Particle Correlations and Fluctuations (2)
- Particle and resonance production (2)
- Particle correlations and fluctuations (2)
- nivolumab (2)
- temozolomide (2)
- ALICE detector (1)
- Angiogenesis (1)
- Anti-nuclei (1)
- Atrial fibrillation (1)
- Boosted Jets (1)
- Cancer genomics (1)
- Catheter ablation (1)
- Collective Flow, (1)
- Cryoballoon (1)
- Electron-pion identification (1)
- Electroweak interaction (1)
- Fibre/foam sandwich radiator (1)
- Follow-up (1)
- HIPPO signalling (1)
- Hadron-Hadron Scattering Heavy (1)
- Hadron-hadron interactions (1)
- Hard Scattering (1)
- Heavy Ion Experiment (1)
- Ionisation energy loss (1)
- Jet Physics (1)
- Jet Substructure (1)
- LHC (1)
- LSCC (1)
- Long non-coding RNAs (1)
- MGMT promoter (1)
- Material budget (1)
- Metabolism (1)
- Multi-Parton Interactions (1)
- Multi-wire proportional drift chamber (1)
- Neural network (1)
- PD-L1 (1)
- Particle and Resonance Production (1)
- Pb–Pb collisions (1)
- Properties of Hadrons (1)
- Proteomics (1)
- QCD (1)
- Quark Deconfinement (1)
- Quark Gluon Plasma (1)
- Quark Production (1)
- Quarkonium (1)
- Radiofrequency (1)
- Rehospitalization (1)
- Relativistic heavy-ion collisions (1)
- TOR signalling (1)
- TR (1)
- Tracking (1)
- Transcriptomics (1)
- Transition radiation detector (1)
- Trigger (1)
- Vector Boson Production (1)
- Xenon-based gas mixture (1)
- biologization (1)
- blood concentrates (1)
- bone-regeneration (1)
- dE/dx (1)
- detector (1)
- ectosomes (1)
- exosomes (1)
- experimental results (1)
- extracellular vesicles (1)
- glioblastoma (1)
- guidelines (1)
- heavy ion experiments (1)
- microparticles (1)
- microvesicles (1)
- minimal information requirements (1)
- newly diagnosed glioblastoma (1)
- platelet-rich-fibrin (1)
- quark gluon plasma (1)
- radiotherapy (1)
- regenerative therapy (1)
- reproducibility (1)
- rigor (1)
- standardization (1)
- unmethylated MGMT (1)
Institute
Vampire bats are the only mammals that feed exclusively on blood. To uncover genomic changes associated with this dietary adaptation, we generated a haplotype-resolved genome of the common vampire bat and screened 27 bat species for genes that were specifically lost in the vampire bat lineage. We found previously unknown gene losses that relate to reduced insulin secretion (FFAR1 and SLC30A8), limited glycogen stores (PPP1R3E), and a unique gastric physiology (CTSE). Other gene losses likely reflect the biased nutrient composition (ERN2 and CTRL) and distinct pathogen diversity of blood (RNASE7) and predict the complete lack of cone-based vision in these strictly nocturnal bats (PDE6H and PDE6C). Notably, REP15 loss likely helped vampire bats adapt to high dietary iron levels by enhancing iron excretion, and the loss of CYP39A1 could have contributed to their exceptional cognitive abilities. These findings enhance our understanding of vampire bat biology and the genomic underpinnings of adaptations to blood feeding.