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Selbst dort, wo Land und Wasser ineinander übergehen, gedeihen bei uns Wälder - die feuchten Sumpfwälder, Bruchwälder und Auwälder. Die naturnahen Feucht- und Nasswälder sind unersetzliche Rückzugsgebiete für Tier- und Pflanzenwelt. Kaum ein anderer Waldlebensraum in unseren gemäßigten Breiten ist so arten- und strukturreich wie diese amphibische Überschneidungszone - und sogleich so bedroht. Diese Broschüre informiert über die Biologe und den Schutz dieser Biotope. Desweiteren gibt sie Aufschluß über Biozönosen und weiterführende Literatur.
Hereditary angioedema (HAE) in children and adolescents : a consensus on therapeutic strategies
(2012)
Hereditary angioedema due to C1 inhibitor (C1 esterase inhibitor) deficiency (types I and II HAE-C1-INH) is a rare disease that usually presents during childhood or adolescence with intermittent episodes of potentially life-threatening angioedema. Diagnosis as early as possible is important to avoid ineffective therapies and to properly treat swelling attacks. At a consensus meeting in June 2011, pediatricians and dermatologists from Germany, Austria, and Switzerland reviewed the currently available literature, including published international consensus recommendations for HAE therapy across all age groups. Published recommendations cannot be unconditionally adopted for pediatric patients in German-speaking countries given the current approval status of HAE drugs. This article provides an overview and discusses drugs available for HAE therapy, their approval status, and study results obtained in adult and pediatric patients. Recommendations for developing appropriate treatment strategies in the management of HAE in pediatric patients in German-speaking countries are provided.Conclusion Currently, plasma-derived C1 inhibitor concentrate is considered the best available option for the treatment of acute HAE-C1-INH attacks in pediatric patients in German-speaking countries, as well as for short-term and long-term prophylaxis.