Universitätspublikationen
Refine
Year of publication
Document Type
- Article (10986)
- Preprint (1708)
- Doctoral Thesis (1575)
- Working Paper (1441)
- Part of Periodical (570)
- Conference Proceeding (513)
- Report (299)
- Part of a Book (107)
- Review (92)
- Book (60)
Language
- English (17455) (remove)
Keywords
- inflammation (95)
- COVID-19 (91)
- SARS-CoV-2 (63)
- Financial Institutions (48)
- climate change (46)
- Germany (45)
- ECB (43)
- aging (43)
- apoptosis (42)
- cancer (42)
Institute
- Medizin (5153)
- Physik (3127)
- Frankfurt Institute for Advanced Studies (FIAS) (1665)
- Wirtschaftswissenschaften (1654)
- Biowissenschaften (1412)
- Informatik (1262)
- Center for Financial Studies (CFS) (1139)
- Sustainable Architecture for Finance in Europe (SAFE) (1068)
- Biochemie und Chemie (858)
- House of Finance (HoF) (704)
- Gesellschaftswissenschaften (618)
- Geowissenschaften (580)
- Biochemie, Chemie und Pharmazie (520)
- Senckenbergische Naturforschende Gesellschaft (386)
- Institut für Ökologie, Evolution und Diversität (383)
- E-Finance Lab e.V. (347)
- Psychologie (334)
- Rechtswissenschaft (288)
- Biodiversität und Klima Forschungszentrum (BiK-F) (278)
- Exzellenzcluster Die Herausbildung normativer Ordnungen (205)
- Pharmazie (197)
- Institute for Monetary and Financial Stability (IMFS) (170)
- Exzellenzcluster Makromolekulare Komplexe (166)
- Informatik und Mathematik (166)
- Psychologie und Sportwissenschaften (166)
- Geowissenschaften / Geographie (162)
- Neuere Philologien (152)
- MPI für Hirnforschung (129)
- MPI für Biophysik (122)
- Mathematik (122)
- Georg-Speyer-Haus (111)
- Buchmann Institut für Molekulare Lebenswissenschaften (BMLS) (105)
- Sportwissenschaften (104)
- Zentrum für Biomolekulare Magnetische Resonanz (BMRZ) (103)
- Sonderforschungsbereiche / Forschungskollegs (102)
- Ernst Strüngmann Institut (95)
- Zentrum für Arzneimittelforschung, Entwicklung und Sicherheit (ZAFES) (90)
- Sprach- und Kulturwissenschaften (87)
- Philosophie (80)
- Präsidium (76)
- Evangelische Theologie (59)
- Kulturwissenschaften (58)
- Erziehungswissenschaften (53)
- Geographie (53)
- Foundation of Law and Finance (50)
- Deutsches Institut für Internationale Pädagogische Forschung (DIPF) (49)
- Geschichtswissenschaften (47)
- MPI für empirische Ästhetik (44)
- Institut für Sozialforschung (IFS) (41)
- Universitätsbibliothek (38)
- ELEMENTS (37)
- Institut für sozial-ökologische Forschung (ISOE) (37)
- Institute for Law and Finance (ILF) (28)
- Philosophie und Geschichtswissenschaften (24)
- Center for Membrane Proteomics (CMP) (17)
- Extern (16)
- Exzellenzcluster Herz-Lungen-System (16)
- Starker Start ins Studium: Qualitätspakt Lehre (14)
- Cornelia Goethe Centrum für Frauenstudien und die Erforschung der Geschlechterverhältnisse (CGC) (13)
- Zentrum für Interdisziplinäre Afrikaforschung (ZIAF) (12)
- Interdisziplinäres Zentrum für Ostasienstudien (IZO) (11)
- Hessische Stiftung für Friedens- und Konfliktforschung (HSFK) (10)
- LOEWE-Schwerpunkt Außergerichtliche und gerichtliche Konfliktlösung (10)
- Sprachwissenschaften (10)
- Interdisziplinäres Zentrum für Neurowissenschaften Frankfurt (IZNF) (9)
- Center for Scientific Computing (CSC) (8)
- LOEWE-Schwerpunkt für Integrative Pilzforschung (8)
- Helmholtz International Center for FAIR (7)
- DFG-Forschergruppen (6)
- Frobenius Institut (6)
- Goethe-Zentrum für Wissenschaftliches Rechnen (G-CSC) (6)
- Zentrum für Weiterbildung (6)
- Institut für Wirtschaft, Arbeit, und Kultur (IWAK) (5)
- Katholische Theologie (5)
- Hochschulrechenzentrum (4)
- Zentrum für Nordamerika-Forschung (ZENAF) (4)
- Frankfurt MathFinance Institute (FMFI) (3)
- Gleichstellungsbüro (3)
- Universität des 3. Lebensalters e.V. (3)
- Sigmund-Freud Institut – Forschungsinstitut fur Psychoanalyse und ihre Anwendungen (2)
- keine Angabe Institut (2)
- (1)
- Akademie für Bildungsforschung und Lehrerbildung (bisher: Zentrum für Lehrerbildung und Schul- und Unterrichtsforschung) (1)
- Diagnostic Center of Acute Leukemia (1)
- Europäische Akademie der Arbeit in der Universität Frankfurt am Main (1)
- Exzellenzcluster (1)
- Fachübergreifend (1)
- Fachübergreifende Einrichtungen (1)
- Forschungscluster (1)
- Institut für Bienenkunde (1)
- Wilhelm-Merton-Zentrum (1)
- keine Angabe Fachbereich (1)
- studiumdigitale (1)
Based on a data sample of 10 billion J/ψ events collected with the BESIII detector, improved measurements of the Dalitz decays η/η′→γe+e− are performed, where the η and η′ are produced through the radiative decays J/ψ→γη/η′. The branching fractions of η→γe+e− and η′→γe+e− are measured to be (7.07±0.05±0.23)×10−3 and (4.83±0.07±0.14)×10−4, respectively. Within the single pole model, the parameter of electromagnetic transition form factor for η→γe+e− is determined to be Λη=(0.749±0.027±0.007) GeV/c2. Within the multi-pole model, we extract the electromagnetic transition form factors for η′→γe+e− to be Λη′=(0.802±0.007±0.008) GeV/c2 and γη′=(0.113±0.010±0.002) GeV/c2. The results are consistent with both theoretical predictions and previous measurements. The characteristic sizes of the interaction regions for the η and η′ are calculated to be (0.645±0.023±0.007) fm and (0.596±0.005±0.006) fm, respectively. In addition, we search for the dark photon in η/η′→γe+e−, and the upper limits of the branching fractions as a function of the dark photon are given at 90\% confidence level.
Based on 4.5 fb−1 of e+e− collision data accumulated at center-of-mass energies between 4599.53 MeV and 4698.82 MeV with the BESIII detector, the decay Λ+c→nK0Sπ+π0 is observed for the first time with a significance of 9.2σ. The branching fraction is measured to be (0.85±0.13±0.03)%, where the first uncertainty is statistical and the second systematic, which differs from the theoretical prediction based on isospin by 4.4σ. This indicates that there may be resonant contributions or some unknown dynamics in this decay.
Using (27.12±0.14)×108 ψ(3686) events collected with the BESIII detector at BEPCII, the decay of ψ(3686)→Ω−K+Ξ¯0+c.c. is observed for the first time. The branching fraction of this decay is measured to be Bψ(3686)→Ω−K+Ξ¯0+c.c.=(2.78±0.40±0.18)×10−6, where the first uncertainty is statistical and the second is systematic. Possible baryon excited states are searched for in this decay, but no evident intermediate state is observed with the current sample size.
The Born cross section of the process e+e−→ΛΛ¯ is measured at 33 center-of-mass energies between 3.51 and 4.60 GeV using data corresponding to the total integrated luminosity of 20.0 fb−1 collected with the BESIII detector at the BEPCII collider. Describing the energy dependence of the cross section requires a contribution from the ψ(3770)→ΛΛ¯ decay, which is fitted with a significance of 4.6-4.9σ including the systematic uncertainty. The lower bound on its branching fraction is 2.4×10−6 at the 90% confidence level (C.L.), at least an order of magnitude larger than expected from predictions using a scaling based on observed electronic widths. This result indicates the importance of effects from vector charmonium(-like) states when interpreting data in terms of e.g., electromagnetic structure observables. The data do not allow for definite conclusions on the interplay with other vector charmonium(-like) states, and we set 90% C.L.upper limits for the products of their electronic widths and the branching fractions.
The Born cross section of the process e+e−→ΛΛ¯ is measured at 33 center-of-mass energies between 3.51 and 4.60 GeV using data corresponding to the total integrated luminosity of 20.0 fb−1 collected with the BESIII detector at the BEPCII collider. Describing the energy dependence of the cross section requires a justification from the ψ(3770)→ΛΛ¯ decay, which is fitted with a significance of 4.9σ with the systematic uncertainty included. The lower bound on its branching fraction is 2.4×10−6 at the 90\% confidence level (C.L.), at least five times larger than expected from predictions using a simple scaling approach. This result indicates the importance of effects from vector charmonium(-like) when interpreting data in terms of {\it e.g.}, electromagnetic structure observables. There are no definite conclusions about the interplay with other vector charmonium(-like), and we set 90\% C.L.upper limits for the products of the electronic widths and the branching fractions.
Using (448.1±2.9)×106 ψ(3686) events collected with the BESIII detector and a single-baryon tagging technique, we present the first observation of the decays ψ(3686)→Ξ(1530)0Ξ¯(1530)0 and Ξ(1530)0Ξ¯0. The branching fractions are measured to be B(ψ(3686)→Ξ(1530)0Ξ¯(1530)0)=(6.77±0.14±0.39)×10−5 and B(ψ(3686)→Ξ(1530)0Ξ¯0)=(0.53±0.04±0.03)×10−5. Here, the first and second uncertainties are statistical and systematic, respectively. In addition, the parameter associated with the angular distribution for the decay ψ(3686)→Ξ(1530)0Ξ¯(1530)0 is determined to be α=0.32±0.19±0.07, in agreement with theoretical predictions within one standard deviation.
Using J/ψ radiative decays from 9.0 billion J/ψ events collected by the BESIII detector, we search for di-muon decays of a CP-odd light Higgs boson (A0), predicted by many new physics models beyond the Standard Model, including the Next-to-Minimal Supersymmetric Standard Model. No evidence for the CP-odd light Higgs production is found, and we set 90% confidence level upper limits on the product branching fraction B(J/ψ→γA0)×B(A0→μ+μ−) in the range of (1.2−778.0)×10−9 for 0.212≤mA0≤3.0 GeV/c2. The new measurement is a 6-7 times improvement over our previous measurement, and is also slightly better than the BaBar measurement in the low-mass region for tanβ=1.
Using J/ψ radiative decays from 9.0 billion J/ψ events collected by the BESIII detector, we search for di-muon decays of a CP-odd light Higgs boson (A0), predicted by many new physics models beyond the Standard Model, including the Next-to-Minimal Supersymmetric Standard Model. No evidence for the CP-odd light Higgs production is found, and we set 90% confidence level upper limits on the product branching fraction B(J/ψ→γA0)×B(A0→μ+μ−) in the range of (1.2−778.0)×10−9 for 0.212≤mA0≤3.0 GeV/c2. The new measurement is a 6-7 times improvement over our previous measurement, and is also slightly better than the BaBar measurement in the low-mass region for tanβ=1.
Using J/ψ radiative decays from 9.0 billion J/ψ events collected by the BESIII detector, we search for di-muon decays of a CP-odd light Higgs boson (A0), predicted by many new physics models beyond the Standard Model, including the Next-to-Minimal Supersymmetric Standard Model. No evidence for the CP-odd light Higgs production is found, and we set 90% confidence level upper limits on the product branching fraction B(J/ψ→γA0)×B(A0→μ+μ−) in the range of (1.2−778.0)×10−9 for 0.212≤mA0≤3.0 GeV/c2. The new measurement is a 6-7 times improvement over our previous measurement, and is also slightly better than the BaBar measurement in the low-mass region for tanβ=1.
Based on 3.19 fb−1 of e+e− collision data accumulated at the center-of-mass energy 4.178 GeV with the BESIII detector operating at the BEPCII collider, the electromagnetic Dalitz decay D∗0→D0e+e− is observed for the first time with a statistical significance of 13.2σ. The ratio of the branching fraction of D∗0→D0e+e− to that of D∗0→D0γ is measured to be (11.08±0.76±0.49)×10−3. By using the world average value of the branching fraction of D∗0→D0γ, the branching fraction of D∗0→D0e+e− is determined to be (3.91±0.27±0.17±0.10)×10−3, where the first uncertainty is statistical, the second systematic and the third external branching fractions.
Based on a data sample of (1.0087±0.0044)×1010 𝐽/𝜓 events collected by the BESIII detector at the BEPCII accelerator, the absolute branching fraction (BF) of the decay 𝐽/𝜓→𝛾𝜂 is measured with high precision using events in which the radiative photon converts to 𝑒+𝑒−. Using the measured absolute BF of 𝐽/𝜓→𝛾𝜂, the absolute BFs of four dominant 𝜂 decay modes are measured for the first time. The results are ℬ(𝐽/𝜓→𝛾𝜂)=(1.067±0.005±0.023)×10−3, ℬ(𝜂→𝛾𝛾)=(39.86±0.04±0.99)%, ℬ(𝜂→𝜋0𝜋0𝜋0)=(31.96±0.07±0.84)%, ℬ(𝜂→𝜋+𝜋−𝜋0)=(23.04±0.03±0.54)%, and ℬ(𝜂→𝜋+𝜋−𝛾)=(4.38±0.02±0.10)%, where the first and second uncertainties are statistical and systematic, respectively. The results are consistent with the world average values within two standard deviations.
Based on a data sample of (1.0087+-0.0044)x10^10 Jpsi events collected by the BESIII detector at the BEPCII accelerator, the absolute branching fraction (BF) of the decay Jpsi->gamma eta is measured with high precision using events in which the radiative photon converts to e+e-. Using the measured absolute BF of Jpsi->gamma eta, the absolute BFs of four dominant eta decay modes are measured for the first time. The results are B(Jpsi->gamma eta) = (1.067+-0.005+-0.023)x10^-3, B(eta->gamma gamma) = (39.86+-0.04+-0.99)%, B(eta->pi0pi0pi0) = (31.96+-0.07+-0.84)%, B(eta->pi+pi-pi0) = (23.04+-0.03+-0.54)%, and B(eta->pi+pi-gamma) = (4.38+-0.02+-0.10)%, where the first and second uncertainties are statistical and systematic, respectively. The results are consistent with the world average values within two standard deviations.
Using e+e− annihilation data corresponding to a total integrated luminosity of 6.32 fb−1 collected at center-of-mass energies between 4.178 and 4.226 GeV with the BESIII detector, we perform an amplitude analysis of the decay D+s→K0SK0Sπ+ for the first time. An enhancement is observed in the K0SK0S mass spectrum near 1.7 GeV/c2, which was not seen in D+s→K+K−π+ in an earlier work, implying the existence of an isospin one partner of the f0(1710). The branching fraction of the decay D+s→K0SK0Sπ+ is determined to be B(D+s→K0SK0Sπ+)=(0.68±0.04stat±0.01syst)%.
Two different experimental approaches were combined to study the electric dipole strength in the doubly-magic nucleus 48Ca below the neutron threshold. Real-photon scattering experiments using bremsstrahlung up to 9.9 MeV and nearly mono-energetic linearly polarized photons with energies between 6.6 and 9.51 MeV provided strength distribution and parities, and an (α,α' γ) experiment at Eα = 136 MeV gave cross sections for an isoscalar probe. The unexpected difference observed in the dipole response is compared to calculations using the first-order random-phase approximation and points to an energy-dependent isospin character. A strong isoscalar state at 7.6 MeV was identified for the first time supporting a recent theoretical prediction.
Neutron star binaries and their associated gravitational wave signal facilitate precision tests of General Relativity. Any deviation of the detected gravitational waveform from General Relativity would therefore be a smoking gun signature of new physics, in the form of additional forces, dark matter particles, or extra gravitational degrees of freedom. To be able to probe new theories, precise knowledge of the expected waveform is required. In our work, we consider a generic setup by augmenting General Relativity with an additional, massive scalar field. We then compute the inspiral dynamics of a binary system by employing an effective field theoretical approach, while giving a detailed introduction to the computational framework. Finally, we derive the modified gravitational waveform at next-to-leading order. As a consequence of our model-agnostic approach, our results are readily adaptable to a plethora of new physics scenarios, including modified gravity theories and scalar dark matter models.
Tidal deformability of fermion-boson stars: neutron stars admixed with ultralight dark matter
(2023)
In this work we investigate the tidal deformability of a neutron star admixed with dark matter, modeled as a massive, self-interacting, complex scalar field. We derive the equations to compute the tidal deformability of the full Einstein-Hilbert-Klein-Gordon system self-consistently, and probe the influence of the scalar field mass and self-interaction strength on the total mass and tidal properties of the combined system. We find that dark matter core-like configurations lead to more compact objects with smaller tidal deformability, and dark matter cloud-like configurations lead to larger tidal deformability. Electromagnetic observations of certain cloud-like configurations would appear to violate the Buchdahl limit. The self-interaction strength is found to have a significant effect on both mass and tidal deformability. We discuss observational constraints and the connection to anomalous detections. We also investigate how this model compares to those with an effective bosonic equation of state and find the interaction strength where they converge sufficiently.
Tidal deformability of fermion-boson stars: neutron stars admixed with ultralight dark matter
(2023)
In this work we investigate the tidal deformability of a neutron star admixed with dark matter, modeled as a massive, self-interacting, complex scalar field. We derive the equations to compute the tidal deformability of the full Einstein-Hilbert-Klein-Gordon system self-consistently, and probe the influence of the scalar field mass and self-interaction strength on the total mass and tidal properties of the combined system. We find that dark matter core-like configurations lead to more compact objects with smaller tidal deformability, and dark matter cloud-like configurations lead to larger tidal deformability. Electromagnetic observations of certain cloud-like configurations would appear to violate the Buchdahl limit. The self-interaction strength is found to have a significant effect on both mass and tidal deformability. We discuss observational constraints and the connection to anomalous detections. We also investigate how this model compares to those with an effective bosonic equation of state and find the interaction strength where they converge sufficiently.
We investigate the impact of non-Hermiticity on the thermodynamic properties of interacting fermions by examining bilinear extensions to the 3+1 dimensional SU(2)-symmetric Nambu--Jona-Lasinio (NJL) model of quantum chromodynamics at finite temperature and chemical potential. The system is modified through the anti-PT-symmetric pseudoscalar bilinear ψ¯γ5ψ and the PT-symmetric pseudovector bilinear iBνψ¯γ5γνψ, introduced with a coupling g. Beyond the possibility of dynamical fermion mass generation at finite temperature and chemical potential, our findings establish model-dependent changes in the position of the chiral phase transition and the critical end-point. These are tunable with respect to g in the former case, and both g and |B|/B0 in the latter case, for both lightlike and spacelike fields. Moreover, the behavior of the quark number, entropy, pressure, and energy densities signal a potential fermion or antifermion excess compared to the standard NJL model, due to the pseudoscalar and pseudovector extension respectively. In both cases regions with negative interaction measure I=ϵ−3p are found. Future indications of such behaviors in strongly interacting fermion systems, for example in the context of neutron star physics, may point toward the presence of non-Hermitian contributions. These trends provide a first indication of curious potential mechanisms for producing non-Hermitian baryon asymmetry. In addition, the formalism described in this study is expected to apply more generally to other Hamiltonians with four-fermion interactions and thus the effects of the non-Hermitian bilinears are likely to be generic.
We investigate the impact of non-Hermiticity on the thermodynamic properties of interacting fermions by examining bilinear extensions to the 3+1 dimensional SU(2)-symmetric Nambu--Jona-Lasinio (NJL) model of quantum chromodynamics at finite temperature and chemical potential. The system is modified through the anti-PT-symmetric pseudoscalar bilinear ψ¯γ5ψ and the PT-symmetric pseudovector bilinear iBνψ¯γ5γνψ, introduced with a coupling g. Beyond the possibility of dynamical fermion mass generation at finite temperature and chemical potential, our findings establish model-dependent changes in the position of the chiral phase transition and the critical end-point. These are tunable with respect to g in the former case, and both g and |B|/B0 in the latter case, for both lightlike and spacelike fields. Moreover, the behavior of the quark number, entropy, pressure and energy densities signal a potential fermion or antifermion excess compared to the standard NJL model, due to the pseudoscalar and pseudovector extension respectively. In both cases regions with negative interaction measure I=ϵ−3p are found. Future indications of such behaviors in strongly interacting fermion systems, for example in the context of neutron star physics, may point toward the presence of non-Hermitian contributions. These trends provide a first indication of curious potential mechanisms for producing non-Hermitian baryon asymmetry. In addition, the formalism described in this study is expected to apply more generally to other Hamiltonians with four-fermion interactions and thus the effects of the non-Hermitian bilinears are likely to be generic.
We investigate the impact of non-Hermiticity on the thermodynamic properties of interacting fermions by examining bilinear extensions to the 3+1 dimensional SU(2)-symmetric Nambu--Jona-Lasinio (NJL) model of quantum chromodynamics at finite temperature and chemical potential. The system is modified through the anti-PT-symmetric pseudoscalar bilinear ψ¯γ5ψ and the PT-symmetric pseudovector bilinear iBνψ¯γ5γνψ, introduced with a coupling g. Beyond the possibility of dynamical fermion mass generation at finite temperature and chemical potential, our findings establish model-dependent changes in the position of the chiral phase transition and the critical end-point. These are tunable with respect to g in the former case, and both g and |B|/B0 in the latter case, for both lightlike and spacelike fields. Moreover, the behavior of the quark number, entropy, pressure, and energy densities signal a potential fermion or antifermion excess compared to the standard NJL model, due to the pseudoscalar and pseudovector extension respectively. In both cases regions with negative interaction measure I=ϵ−3p are found. Future indications of such behaviors in strongly interacting fermion systems, for example in the context of neutron star physics, may point toward the presence of non-Hermitian contributions. These trends provide a first indication of curious potential mechanisms for producing non-Hermitian baryon asymmetry. In addition, the formalism described in this study is expected to apply more generally to other Hamiltonians with four-fermion interactions and thus the effects of the non-Hermitian bilinears are likely to be generic.
Based on electron-positron collision data collected with the BESIII detector operating at the Beijing Electron Positron Collider II storage rings, the value of R≡σ(e+e−→hadrons)/σ(e+e−→μ+μ−) is measured at 14 center-of-mass energies from 2.2324 to 3.6710 GeV. The resulting uncertainties are less than 3.0%, and are dominated by systematic uncertainties.
Based on electron-positron collision data collected with the BESIII detector operating at the Beijing Electron Positron Collider II storage rings, the value of R≡σ(e+e−→hadrons)/σ(e+e−→μ+μ−) is measured at 14 center-of-mass energies from 2.2324 to 3.6710 GeV. The resulting uncertainties are less than 3.0%, and are dominated by systematic uncertainties.
Based on electron-positron collision data collected with the BESIII detector operating at the BEPCII storage rings, the value of R≡σ(e+e−→hadrons)/σ(e+e−→μ+μ−) is measured at 14 center-of-mass energies from 2.2324 to 3.6710 GeV. The resulting uncertainties are less than 3.0%, and are dominated by systematic uncertainties.
Acute brain injuries such as intracerebral hemorrhage (ICH) and ischemic stroke have been reported in critically ill COVID-19 patients as well as in patients treated with veno-venous (VV)-ECMO independently of their COVID-19 status. The purpose of this study was to compare critically ill COVID-19 patients with and without VV-ECMO treatment with regard to acute neurological symptoms, pathological neuroimaging findings (PNIF) and long-term deficits. The single center study was conducted in critically ill COVID-19 patients between February 1, 2020 and June 30, 2021. Demographic, clinical and laboratory parameters were extracted from the hospital’s databases. Retrospective imaging modalities included head computed tomography (CT) and magnetic resonance imaging (MRI). Follow-up MRI and neurological examinations were performed on survivors > 6 months after the primary occurrence. Of the 440 patients, 67 patients received VV-ECMO treatment (15%). Sixty-four patients (24 with VV-ECMO) developed acute neurological symptoms (pathological levels of arousal/brain stem function/motor responses) during their ICU stay and underwent neuroimaging with brain CT as the primary modality. Critically ill COVID-19 patients who received VV-ECMO treatment had a significantly lower survival during their hospital stay compared to those without (p < 0.001). Among patients treated with VV-ECMO, 10% showed acute PNIF in one of the imaging modalities during their ICU stay (vs. 4% of patients in the overall COVID-19 ICU cohort). Furthermore, 9% showed primary or secondary ICH of any severity (vs. 3% overall), 6% exhibited severe ICH (vs. 1% overall) and 1.5% were found to have non-hemorrhagic cerebral infarctions (vs. < 1% overall). There was a weak, positive correlation between patients treated with VV-ECMO and the development of acute neurological symptoms. However, the association between the VV-ECMO treatment and acute PNIF was negligible. Two survivors (one with VV-ECMO-treatment/one without) showed innumerable microhemorrhages, predominantly involving the juxtacortical white matter. None of the survivors exhibited diffuse leukoencephalopathy. Every seventh COVID-19 patient developed acute neurological symptoms during their ICU stay, but only every twenty-fifth patient had PNIF which were mostly ICH. VV-ECMO was found to be a weak risk factor for neurological complications (resulting in a higher imaging rate), but not for PNIF. Although logistically complex, repeated neuroimaging should, thus, be considered in all critically ill COVID-19 patients since ICH may have an impact on the treatment decisions and outcomes.
Sex differences in psychiatric comorbidity and clinical presentation in youths with conduct disorder
(2021)
Background: Conduct disorder (CD) rarely occurs alone but is typically accompanied by comorbid psychiatric disorders, which complicates the clinical presentation and treatment of affected youths. The aim of this study was to investigate sex differences in comorbidity pattern in CD and to systematically explore the ‘gender paradox’ and ‘delayed-onset pathway’ hypotheses of female CD.
Methods: As part of the FemNAT-CD multisite study, semistructured clinical interviews and rating scales were used to perform a comprehensive phenotypic characterization of 454 girls and 295 boys with CD (9–18 years), compared to 864 sex- and age-matched typically developing controls.
Results: Girls with CD exhibited higher rates of current major depression, anxiety disorders, post-traumatic stress disorder and borderline personality disorder, whereas boys with CD had higher rates of current attention-deficit/hyperactivity disorder. In line with the ‘gender paradox’ hypothesis, relative to boys, girls with CD showed significantly more lifetime psychiatric comorbidities (incl. Alcohol Use Disorder), which were accompanied by more severe CD symptoms. Female and male youths with CD also differed significantly in their CD symptom profiles and distribution of age-of-onset subtypes of CD (i.e. fewer girls with childhood-onset CD). In line with the ‘delayed-onset pathway’ hypothesis, girls with adolescent-onset CD showed similar levels of dimensional psychopathology like boys with childhood-onset CD, while boys with adolescent-onset CD had the lowest levels of internalizing psychopathology.
Conclusions: Within the largest study of CD in girls performed to date, we found compelling evidence for sex differences in comorbidity patterns and clinical presentation of CD. Our findings further support aspects of the ‘gender paradox’ and ‘delayed-onset pathway’ hypotheses by showing that girls with CD had higher rates of comorbid lifetime mental disorders and functional impairments, and they usually developed CD during adolescence. These novel data on sex-specific clinical profiles of CD will be critical in informing intervention and prevention programmes.
Non-forest ecosystems, dominated by shrubs, grasses and herbaceous plants, provide ecosystem services including carbon sequestration and forage for grazing, yet are highly sensitive to climatic changes. Yet these ecosystems are poorly represented in remotely-sensed biomass products and are undersampled by in-situ monitoring. Current global change threats emphasise the need for new tools to capture biomass change in non-forest ecosystems at appropriate scales. Here we assess whether canopy height inferred from drone photogrammetry allows the estimation of aboveground biomass (AGB) across low-stature plant species sampled through a global site network. We found mean canopy height is strongly predictive of AGB across species, demonstrating standardised photogrammetric approaches are generalisable across growth forms and environmental settings. Biomass per-unit-of-height was similar within, but different among, plant functional types. We find drone-based photogrammetry allows for monitoring of AGB across large spatial extents and can advance understanding of understudied and vulnerable non-forested ecosystems across the globe.
The more difficult it is to access a research field, the more substantial the need to develop creative methodological models. Investigating the psychosocial impact of migration-related carceral spaces constitutes one such research field. To shed light on these spaces and counter the challenges of opacity, harm, and power asymmetries, we propose a psycho-geographical counter-mapping as a mixed methods approach based on grounded theory (MM-GT). Applying it to immigration detention and refugee confinement sites in Mexico and Samos, our analysis proposes a fully integrated and sequential design that can be adapted to a range of carceral spaces and subjectivation in transdisciplinary research.
Analyzing (448.1±2.9)×106 ψ(3686) events collected with the BESIII detector at the BEPCII collider, the ψ(3686)→ωK0SK0S decay is observed for the first time. The branching fraction for this decay is determined to be Bψ(3686)→ωK0SK0S=(7.04±0.39±0.36)×10−5, where the first uncertainty is statistical and the second is systematic.
Intermediate Mass Ratio Inspirals (IMRIs) will be observable with space-based gravitational wave detectors such as the Laser Interferometer Space Antenna (LISA). To this end, the environmental effects in such systems have to be modeled and understood. These effects can include (baryonic) accretion disks and dark matter (DM) overdensities, so called spikes. For the first time, we model an IMRI system with both an accretion disk and a DM spike present and compare their effects on the inspiral and the emitted gravitational wave signal. We study the eccentricity evolution, employ the braking index and derive the dephasing index, which turn out to be complementary observational signatures. They allow us to disentangle the accretion disk and DM spike effects in the IMRI system.
Intermediate Mass Ratio Inspirals (IMRIs) will be observable with space-based gravitational wave detectors such as the Laser Interferometer Space Antenna (LISA). To this end, the environmental effects in such systems have to be modeled and understood. These effects can include (baryonic) accretion disks and dark matter (DM) overdensities, so called spikes. For the first time, we model an IMRI system with both an accretion disk and a DM spike present and compare their effects on the inspiral and the emitted gravitational wave signal. We study the eccentricity evolution, employ the braking index and derive the dephasing index, which turn out to be complementary observational signatures. They allow us to disentangle the accretion disk and DM spike effects in the IMRI system.
Schülerlabor Künstliche Intelligenz – Verhaltensforschung im Biologieunterricht mit neuen Methoden
(2023)
Die Verhaltensbiologie ist ein wichtiger Inhalt im Biologieunterricht. Das zielgerichtete, forschende Beobachten bereitet den Schüler/-innen jedoch häufg Schwierigkeiten und sollte vor allem praktisch eingeübt werden. Das Schülerlabor KILab bietet dafür eine innovative Möglichkeit.
Manipulation of neuronal or muscular activity by optogenetics or other stimuli can be directly linked to the analysis of Caenorhabditis elegans (C. elegans) body length. Thus, WormRuler was developed as an open-source video analysis toolbox that offers video processing and data analysis in one application. Utilizing this novel tool, the super red-shifted channelrhodopsin variant, ChrimsonSA, was characterized in C. elegans. Expression and activation of ChrimsonSA in GABAergic motor neurons results in their depolarization and therefore elongation of body length, the extent of which providing information about the strength of neuronal transmission.
The relationship between external and internal load parameters in 3 × 3 basketball tournaments
(2022)
Purpose: 3 × 3 basketball games are characterized by high-intensity accelerations and decelerations, and a high number of changes of direction and jumps. It is played in tournament form with multiple games per day. Therefore, optimal regeneration is crucial for maintaining a high performance level over the course of the tournament. To elucidate how load of a match affects the athletes' bodies (i.e., internal load), muscular responses to the load of 3 × 3 games were analyzed. We aimed to investigate changes in contractility of the m. rectus femoris (RF) and m. gastrocnemius medialis (GC) in response to the load of single 3 × 3 games and a 3 × 3 tournament.
Methods: Inertial movement analysis was conducted to capture game load in 3 × 3. Changes in contractility were measured using tensiomyography (TMG). During a two-day tournament, TMG measurements were conducted in the morning and after each game. Additionally, off-game performance analysis consisting of jump and change-of-direction (COD) tests was conducted the day before the tournament.
Results: Significant changes of the muscle contractility were found for GC with TMG values being higher in the baseline than in the post-game measurements. In contrast to athletes of the GC group, athletes of the RF group responded with either decreased or increased muscle contractility after a single 3 × 3 game. A significant correlation between external and internal load parameters could not be shown. Concerning off-game performance, significant correlations can be reported for COD test duration, CMJ height and ∆Vc as well as COD test duration and ∆Dm. No systematic changes in muscle contractility were found over the course of the tournament in RF and GC.
Conclusion: The athletes' external 3 × 3 game load and their performance level did not seem to affect muscular contractility after a single 3 × 3 game or a complete 3 × 3 tournament within this investigation. This might indicate that elite athletes can resist external load without relevant local muscular fatigue. With respect to the course of the tournament, it can therefore be concluded that the breaks between games seem to be sufficient to return to the initial level of muscle contractility.
Significant progress has been made in the management of Wilms tumor (WT) in recent years, mostly as a result of collaborative efforts and the implementation of protocol-driven, multimodal therapy. This article offers a comprehensive overview of current multidisciplinary treatment strategies for WT, whilst also addressing recent technical innovations including nephron-sparing surgery (NSS) and minimally invasive approaches. In addition, surgical concepts for the treatment of metastatic disease, advances in tumor imaging technology and potentially prognostic biomarkers will be discussed. Current evidence suggests that, in experienced hands and selected cases, laparoscopic radical nephrectomy and laparoscopic-assisted partial nephrectomy for WT may offer the same outcome as the traditional open approach. While NSS is the standard procedure for bilateral WT, NSS has evolved as an alternative technique in patients with smaller unilateral WT and in cases with imminent renal failure. Metastatic disease of the lung or liver that is associated with WT is preferably treated with a three-drug chemotherapy and local radiation therapy. However, surgical sampling of lung nodules may be advisable in persistent nodules before whole lung irradiation is commenced. Several tumor markers such as loss of heterozygosity of chromosomes 1p/16q, 11p15 and gain of function at 1q are associated with an increased risk of recurrence or a decreased risk of overall survival in patients with WT. In summary, complete resection with tumor-free margins remains the primary surgical aim in WT, while NSS and minimally invasive approaches are only suitable in a subset of patients with smaller WT and low-risk disease. In the future, advances in tumor imaging technology may assist the surgeon in defining surgical resection margins and additional biomarkers may emerge as targets for development of new diagnostic tests and potential therapies.
Objectiv:e To explore the association of physical activity (PA) with musculoskeletal pain (MSK pain).
Design: Cross-sectional study
Setting: 14 countries (Argentina, Australia, Austria, Brazil, Chile, France, Germany, Italy, the Netherlands, Singapore, South Africa, Spain, Switzerland and the USA).
Participants: Individuals aged 18 or older.
Primary and secondary outcome measures: PA volumes were assessed with an adapted version of the Nordic Physical Activity Questionnaire-short. Prevalence of MSK pain was captured by means of a 20-item checklist of body locations. Based on the WHO recommendation on PA, participants were classified as non-compliers (0–150 min/week), compliers (150–300 min/week), double compliers (300–450 min/week), triple compliers (450–600 min/week), quadruple compliers (600–750 min/week), quintuple compliers (750–900 min/week) and top compliers (more than 900 min/week). Multivariate logistic regression was used to obtain adjusted ORs of the association between PA and MSK pain for each body location, correcting for age, sex, employment status and depression risk.
Results: A total of 13 741 participants completed the survey. Compared with non-compliers, compliers had smaller odds of MSK pain in one location (thoracic pain, OR 0.77, 95% CI 0.64 to 0.93). Double compliance was associated with reduced pain occurrence in six locations (elbow, OR 0.70, 95% CI 0.50 to 0.98; forearm, OR 0.63, 95% CI 0.40 to 0.99; wrist, OR 0.74, 95% CI 0.57 to 0.98; hand, OR 0.57, 95% CI 0.40 to 0.79; fingers, OR 0.72, 95% CI 0.52 to 0.99; abdomen, OR 0.61, 95% CI 0.41 to 0.91). Triple to top compliance was also linked with lower odds of MSK pain (five locations in triple compliance, three in quadruple compliance, two in quintuple compliance, three in top compliance), but, at the same time, presented increased odds of MSK pain in some of the other locations.
Conclusion: A dose of 300–450 min WHO-equivalent PA/week was associated with lower odds of MSK pain in six body locations. On the other hand, excessive doses of PA were associated with higher odds of pain in certain body locations.
The international system of states displays an inherent drive to territorialize the global commons. But territorialization is not a continuous process—it occurs in episodes. In this article, I use one case from ocean governance, the expansion of territory into near‐shore areas of the seas, to advance a twofold argument about the nature of these episodes. First, I argue that the root causes of this drive to territorialize “empty space” are located in global politics, norms, and economics. Second, a territorializing episode occurs when there are impelling economic incentives, and when great powers are unable or unwilling to oppose territorialization. However, this can lead to different outcomes: sovereign territories, functional territories, or internationalized territories. Oceanic space has seen a series of these territorializing episodes since the end of the Second World War and functional territorialization has become more prevalent over time.
Social identification is health-beneficial as social groups provide social support (i.e., the social cure effect). We study this social cure effect in diabetes patients by focusing on two relevant sources of social support, namely medical practitioners (MP) and fellow patients. As both groups have diabetes-specific knowledge, we predict that sharing an identity with them provides access to specific support, which, in turn, optimizes individuals’ diabetes management and reduces diabetes-related stress. We further predict that identifying with their MP or fellow patients will be more strongly related to perceived social support among individuals with lower diabetes-specific resilience because they pay more attention to supportive cues. We tested this moderated mediation model in a two-wave study with n = 200 diabetes patients. Identification with the MP related to more support, which, in turn, was related to better diabetes management and less diabetes-specific stress. Identification with fellow patients related to more support; however, social support was unrelated to diabetes management and stress. Resilience only moderated the relationship between MP identification and support, as people with lower resilience levels reported more support from their MP. This study shows the importance of social identification with the MP and other diabetes patients, especially for people with lower resilience levels.
Based on (10087±44)×106 J/ψ events collected with the BESIII detector, the process J/ψ→γπ+π−η′ is studied using two dominant decay channels of the η′ meson, η′→γπ+π− and η′→ηπ+π−,η→γγ. The X(2600) is observed with a statistical significance larger than 20σ in the π+π−η′ invariant mass spectrum, and it has a strong correlation to a structure around 1.5 GeV/{\it c}2 in the π+π− invariant mass spectrum. A simultaneous fit on the π+π−η′ and π+π− invariant mass spectra with the two η′ decay modes indicates that the mass and width of the X(2600) state are 2617.8±2.1+18.2−1.9 MeV/{\it c}2 and 200±8+20−17 MeV, respectively. The corresponding branching fractions are measured to be B(J/ψ→γX(2600))⋅B(X(2600)→f0(1500)η′)⋅B(f0(1500)→π+π−) = (3.39±0.18+0.91−0.66)×10−5 and B(J/ψ→γX(2600))⋅B(X(2600)→f′2(1525)η′)⋅B(f′2(1525)→π+π−) = (2.43±0.13+0.31−1.11)×10−5, where the first uncertainties are statistical, and the second systematic.
Based on a sample of (10.09±0.04)×109 J/ψ events collected with the BESIII detector operating at the BEPCII storage ring, a partial wave analysis of the decay J/ψ→γηη′ is performed. An isoscalar state with exotic quantum numbers JPC=1−+, denoted as η1(1855), has been observed for the first time with statistical significance larger than 19σ. Its mass and width are measured to be (1855±9+6−1)~MeV/c2 and (188±18+3−8)~MeV, respectively. The product branching fraction B(J/ψ→γη1(1855)→γηη′) is measured to be (2.70±0.41+0.16−0.35)×10−6. The first uncertainties are statistical and the second are systematic. In addition, an upper limit on the branching ratio B(f0(1710)→ηη′)/B(f0(1710)→ππ) is determined to be 1.61×10−3 at 90\% confidence level, which lends support to the hypothesis that the f0(1710) has a large glueball component.
Study of ψ(3686) → ΛΛ¯ω
(2022)
Based on a data sample of (448.1±2.9)×106 ψ(3686) events collected with the BESIII detector at the BEPCII collider, the branching fraction of ψ(3686)→ΛΛ¯ω is measured to be (3.30±0.34(stat.)±0.29(syst.))×10−5 for the first time. In addition, the Λω (or Λ¯ω) invariant mass spectra is studied and the potential presence of excited Λ states has been investigated.
The study of the Cabibbo-favored semileptonic decay Λ+𝑐→Λ𝑒+𝜈𝑒 is reported using a 4.5 fb−1 data sample of 𝑒+𝑒− annihilations collected at center-of-mass energies ranging from 4.600 GeV to 4.699 GeV with the BESIII detector at the BEPCII collider. The branching fraction of the decay is measured to be ℬ(Λ+𝑐→Λ𝑒+𝜈𝑒)=(3.56±0.11stat±0.07syst)%, which is the most precise measurement to date. Furthermore, we perform an investigation of the internal dynamics in Λ+𝑐→Λ𝑒+𝜈𝑒. We provide the first direct comparisons of the differential decay rate and form factors with those predicted from lattice quantum chromodynamics (LQCD) calculations. Combining the measured branching fraction with a 𝑞2-integrated rate predicted by LQCD, we determine 𝑉𝑐𝑠|=0.936±0.017ℬ±0.024LQCD±0.007𝜏Λ𝑐.
Based on a sample of 4.4 fb−1 of e+e− annihilation data collected in the energy region between 4.6 GeV and 4.7 GeV with the BESIII detector at BEPCII, two singly Cabibbo-suppressed decays Λ+c→Σ0K+ and Λ+c→Σ+K0S are studied. The ratio of the branching fraction B(Λ+c→Σ0K+) relative to B(Λ+c→Σ0π+) is measured to be 0.0361±0.0073(stat.)±0.0005(syst.), and the ratio of B(Λ+c→Σ+K0S) relative to B(Λ+c→Σ+π+π−) is measured to be 0.0106±0.0031(stat.)±0.0004(syst.). After taking the world-average branching fractions of the reference decay channels, the branching fractions B(Λ+c→Σ0K+) and B(Λ+c→Σ+K0S) are determined to be (4.7±0.9(stat.)±0.1(syst.)±0.3(ref.))×10−4 and (4.8±1.4(stat.)±0.2(syst.)±0.3(ref.))×10−4, respectively. The branching fraction of the Λ+c→Σ+K0S decay is measured for the first time.
Using 4.5 fb−1 of e+e− annihilation data samples collected at the center-of-mass energies ranging from 4.600~GeV to 4.699~GeV with the BESIII detector at the BEPCII collider, a first study of the semileptonic decays Λ+c→pK−e+νe, Λ+c→Λ(1520)e+νe and Λ+c→Λ(1405)e+νe is performed. The Λ+c→pK−e+νe decay is observed with a significance of 8.2σ and the branching fraction is measured to be B(Λ+c→pK−e+νe)=(0.88±0.17stat.±0.07syst.)×10−3. We also report evidence of Λ+c→Λ(1520)e+νe and Λ+c→Λ(1405)e+νe with significances of 3.3σ and 3.2σ, respectively, and measure B(Λ+c→Λ(1520)e+νe)=(1.02±0.52stat.±0.11syst.)×10−3 and B(Λ+c→Λ(1405)[→pK−]e+νe)=(0.42±0.19stat.±0.04syst.)×10−3. Combining these with the inclusive semileptonic Λ+c branching fraction measured by BESIII, the relative fraction is determined to be [B(Λ+c→pK−e+νe)/B(Λ+c→Xe+νe)]=(2.1±0.4stat.±0.2syst.)%, which provides a clear confirmation that semileptonic Λ+c decays are not saturated by the Λℓ+νℓ final state.
Using (448.1±2.9)×106 ψ(3686) events collected with the BESIII detector, we perform the first search for the weak baryonic decay ψ(3686)→Λ+cΣ¯−+c.c.. The analysis procedure is optimized using a blinded method. No significant signal is observed, and the upper limit on the branching fraction (B) of ψ(3686)→Λ+cΣ¯−+c.c. is set to be 1.4×10−5 at the 90\% confidence level.
Using (448.1±2.9)×106 ψ(3686) events collected with the BESIII detector, we perform the first search for the weak baryonic decay ψ(3686)→Λ+cΣ¯−+c.c.. The analysis procedure is optimized using a blinded method. No significant signal is observed, and the upper limit on the branching fraction (B) of ψ(3686)→Λ+cΣ¯−+c.c. is set to be 1.4×10−5 at the 90\% confidence level.
Using (448.1±2.9)×106 ψ(3686) events collected with the BESIII detector, we perform the first search for the weak baryonic decay ψ(3686)→Λ+cΣ¯−+c.c.. The analysis procedure is optimized using a blinded method. No significant signal is observed, and the upper limit on the branching fraction (B) of ψ(3686)→Λ+cΣ¯−+c.c. is set to be 1.4×10−5 at the 90\% confidence level.
Based on 7.33 fb−1 of e+e− collision data taken at center-of-mass energies between 4.128 and 4.226 GeV with the BESIII detector, we measure the branching fraction of D∗+s→D+sπ0 relative to that of D∗+s→D+sγ to be (6.16±0.43±0.19)%. The first uncertainty is statistical and the second one is systematic. By using the world average value of the branching fraction of D∗+s→D+se+e−, we determine the branching fractions of D∗+s→D+sγ and D∗+s→D+sπ0 to be (93.57±0.44±0.19)% and (5.76±0.44±0.19)%, respectively.
Based on 7.33 fb−1 of e+e− collision data taken at center-of-mass energies between 4.128 and 4.226 GeV with the BESIII detector, we measure the branching fraction of D∗+s→D+sπ0 relative to that of D∗+s→D+sγ to be (6.16±0.43±0.19)%. The first uncertainty is statistical and the second one is systematic. By using the world average value of the branching fraction of D∗+s→D+se+e−, we determine the branching fractions of D∗+s→D+sγ and D∗+s→D+sπ0 to be (93.57±0.44±0.19)% and (5.76±0.44±0.19)%, respectively.