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Englische Fassung: Societal Constitutionalism: Alternatives to State-centred Constitutional theory? ("Storrs Lectures 2003/04" Yale Law School) In: Christian Joerges, Inge-Johanne Sand und Gunther Teubner (Hg.) Constitutionalism and Transnational Governance. Hart, Oxford 2004, 3-28. Und in: Ius et Lex 2004, S.31-50. Französische Fassung: Constitutionalisme sociétal et globalisation: Alternatives à la théorie constitutionelle centrée sur l'État. Themis 2005 (im Erscheinen) Italienische Fassung: Costituzionalismo societario: alternative alla teoria costituzionale stato-centrica. In: Gunther Teubner, Costituzionalismo societario. Armando, Roma 2005 (im Erscheinen). Spanische Fassung: Globalización y constitucionalismo social: alternativas a la teoría constitucionalista centrada en el Estado". In: Carlos Gómez-Jara Díez (Hg.), Teoría de sistemas y Derecho penal: Fundamentos y posibilidades de aplicación. Granada: Comares, 2005 (im Erscheinen) und in: Cancio Meliá und Bacigalupo Saggese (Hg.) Derecho penal y política transnacional. Barcelona: Atelier, 2005 (in Erscheinen)und in: Gunther Teubner, El Derecho como sistema autopoiético de la sociedad global, herausgegeben von Carlos Gómez-Jara Diez. Bogotá: Universidad Externado de Colombia, 2005 (im Erscheinen) und Lima: ARA Editores, 2005 (im Erscheinen) Polnische Fassung: Konstytucjonalizm spoleczny: Alternatywy dla teorii konstitucyjnej nakierowanej na panstwo. Ius et Lex 3, 2004, S.5-27.
This paper is focused on the coordination of order and production policy between buyers and suppliers in supply chains. When a buyer and a supplier of an item work independently, the buyer will place orders based on his economic order quantity (EOQ). However, the buyer s EOQ may not lead to an optimal policy for the supplier. It can be shown that a cooperative batching policy can reduce total cost significantly. Should the buyer have the more powerful position to enforce his EOQ on the supplier, then no incentive exists for him to deviate from his EOQ in order to choose a cooperative batching policy. To provide an incentive to order in quantities suitable to the supplier, the supplier could offer a side payment. One critical assumption made throughout in the literature dealing with incentive schemes to influence buyer s ordering policy is that the supplier has complete information regarding buyer s cost structure. However, this assumption is far from realistic. As a consequence, the buyer has no incentive to report truthfully on his cost structure. Moreover there is an incentive to overstate the total relevant cost in order to obtain as high a side payment as possible. This paper provides a bargaining model with asymmetric information about the buyer s cost structure assuming that the buyer has the bargaining power to enforce his EOQ on the supplier in case of a break-down in negotiations. An algorithm for the determination of an optimal set of contracts which are specifically designed for different cost structures of the buyer, assumed by the supplier, will be presented. This algorithm was implemented in a software application, that supports the supplier in determining the optimal set of contracts.
Die zunehmende Monopolisierung auf dem Markt für Informationsressourcen im akademischen Sektor führte in den vergangenen Jahren zu einer verstärkten Bildung von Bibliothekskonsortien auf der Abnehmerseite, die einen Gegenpol in Form einer Einkaufsgenossenschaft darstellen sollten [McCa02]. Diese Tendenzen lassen sich in verschiedenen Ländern wie etwa in Deutschland, England, der Schweiz und der Niederlande beobachten [Okerso]. In den USA sind Konsortien eher selten zu finden; das größte Konsortium ist hier OHIO-Link (http://www.lib.ohio-state.edu/). In Deutschland richten sich die meisten Konsortien wegen der föderalen Finanzierungsstrukturen regional aus; überregionale bzw. deutschlandweite Konsortien sind derzeit noch selten. Ein Zusammenschluss auf thematischer Grundlage findet derzeit so gut wie gar nicht statt, vielmehr werden möglichst viele Bibliotheken in Konsortien unabhängig von den an den jeweiligen Standorten betriebenen Forschungsschwerpunkten eingebunden [AnDe02]....
Introduction: This open label, multicentre study was conducted to assess the times to offset of the pharmacodynamic effects and the safety of remifentanil in patients with varying degrees of renal impairment requiring intensive care.
Methods: A total of 40 patients, who were aged 18 years or older and had normal/mildly impaired renal function (estimated creatinine clearance ≥ 50 ml/min; n = 10) or moderate/severe renal impairment (estimated creatinine clearance <50 ml/min; n = 30), were entered into the study. Remifentanil was infused for up to 72 hours (initial rate 6–9 μg/kg per hour), with propofol administered if required, to achieve a target Sedation–Agitation Scale score of 2–4, with no or mild pain.
Results: There was no evidence of increased offset time with increased duration of exposure to remifentanil in either group. The time to offset of the effects of remifentanil (at 8, 24, 48 and 72 hours during scheduled down-titrations of the infusion) were more variable and were statistically significantly longer in the moderate/severe group than in the normal/mild group at 24 hours and 72 hours. These observed differences were not clinically significant (the difference in mean offset at 72 hours was only 16.5 min). Propofol consumption was lower with the remifentanil based technique than with hypnotic based sedative techniques. There were no statistically significant differences between the renal function groups in the incidence of adverse events, and no deaths were attributable to remifentanil use.
Conclusion: Remifentanil was well tolerated, and the offset of pharmacodynamic effects was not prolonged either as a result of renal dysfunction or prolonged infusion up to 72 hours.
The study of organisms with restricted dispersal abilities and presence in the fossil record is particularly adequate to understand the impact of climate changes on the distribution and genetic structure of species. Trochoidea geyeri (Soós 1926) is a land snail restricted to a patchy, insular distribution in Germany and France. Fossil evidence suggests that current populations of T. geyeri are relicts of a much more widespread distribution during more favourable climatic periods in the Pleistocene. Results: Phylogeographic analysis of the mitochondrial 16S rDNA and nuclear ITS-1 sequence variation was used to infer the history of the remnant populations of T. geyeri. Nested clade analysis for both loci suggested that the origin of the species is in the Provence from where it expanded its range first to Southwest France and subsequently from there to Germany. Estimated divergence times predating the last glacial maximum between 25–17 ka implied that the colonization of the northern part of the current species range occurred during the Pleistocene. Conclusion: We conclude that T. geyeri could quite successfully persist in cryptic refugia during major climatic changes in the past, despite of a restricted capacity of individuals to actively avoid unfavourable conditions.
We present a method for the construction of a Krein space completion for spaces of test functions, equipped with an indefinite inner product induced by a kernel which is more singular than a distribution of finite order. This generalizes a regularization method for infrared singularities in quantum field theory, introduced by G. Morchio and F. Strocchi, to the case of singularites of infinite order. We give conditions for the possibility of this procedure in terms of local differential operators and the Gelfand-Shilov test function spaces, as well as an abstract sufficient condition. As a model case we construct a maximally positive definite state space for the Heisenberg algebra in the presence of an infinite infrared singularity. See the corresponding paper: Schmidt, Andreas U.: "Mathematical Problems of Gauge Quantum Field Theory: A Survey of the Schwinger Model" and the presentation "Infinite Infrared Regularization in Krein Spaces"