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Aeration in higher plants
(1979)
A sketch of Houailou grammar
(1978)
Houailou is an Oceanic language spoken by approximately 7,000 people in central New Caledonia. Haudricourt, in his classification of the New Caledonia Languages, assigns Houailou to his Southern Group (Haudricourt, 1971). The following grammatical description of Houailou is based primarily on J. de La Fontinelle's La langue de Houailou (La Fontinelle 1976). Since La Fontinellels grammar uses a Pramework that makes comparison of Houailou to other Oceanic-languages rather difficult, it was felt that it might be a worth-while undertaking to rewrite it in a more traditional framework. The main differences between La Fontinelle's treatment of Houailou and its present reinterpretation can be briefly characterized as follows: La Fontinelle begins her description by isolating minimal gramaatical categories and then determitles their cooccurrence privileges in larger constructions. ...
In order to elucidate what species among so many kind of marine organisms are likely to be consmed Iargely by the balaenopterid whales, the existing evidence on the food habits of baleen whales is reviewed. To meet with this primary purpose the report was mainly focussed on to describe qualitative aspects of food species having been known to date from the notable whaling grounds over the world rather than documenting quantitative subjects. One of interesting facts noticed throughout the contribution was that there exists fairly intense diversity in the assembly of food species composition by regions such as; northern hemisphere vs. southern hemisphere, Pacific region vs. Atlantic region, inshore waters vs. offshore waters, embayed waters vs. open waters, where the former usually shows more diversed complexity than the latter. The fact however suggests that although the composition of food species locally varies over the various whaling grounds, the food organisms as taxonomical groups are very similar one another even in locally isolated whaIing grounds when the food organisms and their assemblies are considered by the family or genus basis. In this connection many evidences given in the text may suggest that the balaenopterid whales as a whole may substantially live on quite simply compositioned forage assembly in comparison with tremendous variety of organisms existing in the marine ecosystems. One of important aspects of the baleen whales food must be found in their characteristics of forming dense swarms, schools, and/or aggregations in the shallower enough layers to be fed by the whales. The present and past status of larger baleen whales as the mighty monarch through their evolutional pathways may entirely depend upon the spatial distribution pattern of possible food organisms, i.e. the animal aggregations.
There is an inexhaustible stream of theoretical work on aspect. More than 20 major books of a gelteral nature have come out during the past few years, not to mention the vast amount of shorter articles. The theoretical proposals found in these works are often radically different. What is the state of the art in this highly controversial area? To what extent can the "ordinary working linguist" profit from the flood of theoretical proposals? This paper started out as a review article on five recent books on aspect. These reviews are incorporated here into a general assessment of contemporary aspect theories. We will classify different approaches to aspect and try to sort out their theoretical primitives. The paper concludes wich a brief summary pointing out the most urgent desiderata for a typologically adequate approach to aspect.
A systematic revision of the genus Dichaeu (Orchidaceae) in Costa Rica is presented. The taxonomic history of the genus and its phylogenetic position are discussed, with emphasis on infragenenc grouping. Characters of vegetative and floral morphology are treated, and their taxonoiilic significance is discussed. Twenty-nine Dichnea taxa are recognized for the flora of Costa Rica, and a key to species is provided. Each taxon is described on the basis of Costa Rican material, illustrated in a composite plate, and its distribution in the country is assessed. Distribution maps for all the taxa are given. Overall distribution, derivation of name, notes on species ecology, and diagnostic features are presented for each taxon. Lectotypes are selectcd for D. acostae Schltr., D. acroblephara Schltr., D. amparoana Schltr., D. costaricensis Schltr., D. dammeriana Kraenzl., D. lycopodioides Rchb. f. ex Kraenzl., D. poicillantha Schltr., D. selaginella Schltr., D. tuercklheimii Schltr., Epidendrum echinocarpon Sw., and E. trichocarpon Sw. A new species, D. gomez-lauritoi, is described and illustrated from the wet Caribbean plains of central Costa Rica.
If the Bosnian crisis of 1908-9 may properly be described as the dress rehearsal for 1914, the Austrian project, announced early in 1908, to construct a railway from the Bosnian border through the Sandjalc of Novibazar helped to set the stage. Part of the original program to link up the Ottoman realm with central Europc by iron highways, this line had been overlooked for decades as finance, engineering, and diplomacy spent themselves on the great trunk line, the Orientbahn, running like a backbone down the Balkans to Constantinople, with a branch connecting Nish with Salonica via Uskub. From Uskub a spur penetrated northward to Mitrovitza; another linked Salonica with Monastir. Though small in itself, the reappearance of the Novibazar scheme heralded the revival of the perennial Austro-Russian rivalry over the Near East in an acute form, sharpened international animosities generally, strengthened latent dreads of Teutonic hegemony over the Balkans, and gave an impetus to a plethora of competing railway projects. In spite of Austria's renunciation of her rights in the Sandjak as part of the settlement attendant upon the annexation of Bosnia-Herzegovina, the railway plan was not abandoned, and until well along in 1909 hopes were cherished that the Sandjak road - even today unconstructed - would be built.
The present paper introduces a new dataset, the Rand American Life Panel (ALP), which offers several appealing features for an analysis of financial literacy and retirement planning. It allows us to evaluate financial knowledge during workers’ prime earning years when they are making key financial decisions, and it offers detailed financial literacy and retirement planning questions, permitting a finer assessment of respondents’ financial literacy than heretofore feasible. We can also compare respondents’ self-assessed financial knowledge levels with objective measures of financial literacy, and most valuably, we can investigate prior financial training which permits us to identify key causal links. By every measure, and in every sample we examine, financial literacy proves to be a key determinant of retirement planning. We also find that respondent literacy is higher when they were exposed to economics in school and to company-based financial education programs. JEL Classification: D91
A taxonomic revision of the genus Syntrichia Brid. (Pottiaceae, Musci) in the Mediterranean Region and Macaronesia has been carried out, thus contributing to knowledge of its distinguisliing morphological characters, geographic distribution and nomenclature. Some 3000 specimens, including the most of type material, were studied. An identification key, morphological descriptions, photographs and numerous observations on taxonomic and nomenclatural problems of the 23 taxa accepted in the study area, are provided. New records for some countries of the Mediterranean basin and Macaronesia are given. Five new Synonyms are proposed. The designations of 11 new lectotypes are included and the name Syntrichia aciphylla var. calva J.J. Amann is excluded from the genus Syntrichia.
This review study updates the Mediterranean fish species inventory (Agnatha, Gnathostoma). Comments upon regional particularities, endemicities, immigrations, emigrations and the recent movements of Mediterranean fauna are made. A comparafive analysis between the fish communities of the Mediterranean und those of neighbouring seas is sketched out.
A new experimental system has been set up with the ability to investigate catalytic processes and charge transfer of acrylonitrile on copper. For this purpose a new Time of Flight Mass Spectrometer to measure both the reaction outcome and electron energy distributions has been designed and tested. First experiments have been carried out, in which the width of the two-photon photoelectron energy distribution can be varied by changing the wavelength of the incident laser beam. This method allows high precision measurements of the work function and will be useful in the study with adsorbates, physi- or chemisorbed. In first adsorption measurements the excitation of vibrational modes of acrylonitrile has been seen to be consistent with earlier gas-phase experiments. Electron energy spectra taken with the electron analyzer with high resolution showed a clear defect in the electron yield at energies around the energy of one vibrational mode, indicating the possibility of resonant vibrational excitation by electron impact. More indications to that process were found i first electron spectra from the new TOF-MS, since a threshold for the capture probability is found at energies close to vibrational excitation. The threshold vanishes when the exposure is amplified significantly, indicating that electrons are scattered multiple and no resonance are be observed anymore. The experiments carried out were just the starting point in understanding the mechanism of the reaction. A new femtosecond laser system which is currently set up will give not only a time-resolved information on the reaction pathways but also give the possibility to create non-thermal electrons and to study intermediate states of the photoemission and the influence of the adsorbate on them. In addition the rotation of the electron analyzer will permit angle-resolved measurements of the scattering process of the electrons and the vibrational excitation via this pathway. With the new cooling system applied it will also be interesting to study the excitation process at lower temperatures. Below -160° C there are different geometries of the molecule predicted to be present at the surface. At these temperatures the thermal effects should play a major role, so that a thermal decoupling of the electrons is very desirable.
This paper deals with the anthomyiid-flies from Korea. A total of 81 species belonging to 22 genera are represented in Korean fauna as the result, among them the following 9 species are proposed here new to science as: Anthomyia koreana sp. nov., Botanophila seungrnoi sp. nov., Acklandia koreacola sp. nov., Lasiomma monticola sp nov., Egle podulparia sp. nov., Delia expansa sp. nov., Phorbia soyosana sp. nov., P. dissimiiis sp. nov., P. taeguensis sp. nov., and 2 genera, Acklandia Hennig, 1976, Egle Robineau-Desvoidy, 1830, with the below 12 species are newly recorded from Korea as: Parapegomyia schineri, Nupedia debilis, Botanophila striolata, Egle muscaria, E. longipalpis, E. parvaeformis, E. panta, E. korpokkur, Paregle vetula, Delia tenuiventris, D. coronariae, Phorbia longipilis. Keys are given for all the taxa respectively, some illustrations of various characters for identification are provided. Arranged are host plants and domestic localities for each species.
The present work deals with the problem of the essential factor regulating the wing-stroke frequency in some insects in wing mutilation and loading experiments and in subatmospheric air pressure experiments. The diverse opinions concerning this factor, appearing in the literature, are reviewed. As appears in this review, one of two factors, the inertia of the wings or the resistance of the gas medium, is claimed to be the main regulator of the wingstroke frequency. Therefore two series of experiments have been performed. In the first series the correlation between the moment oi inertia of the wings and the wing-stroke frequency is examined. The wings are mutilated by cutting them transversely, longitudinally or obliquely or loaded with a drop of collodion. It is found that (1) the wing-stroke frequency is proportional to the -0.35th power of the moment of inertia of the wings, that (2) this applies to both mutilation and loading experiments, that (3) it makes no difference whether the procedures are equal or unequal on both sides or only one-sided, and that (4) the frequency tends not to rise above a certain lirnit in mutilation experiments. In the second series of experiments the correlation between the pressure of the gas medium and the wing-stroke frequency is examined. It is found that the effect of pressure varies greatly in different insects and may even be totally absent. The wing-stroke frequency is proportional to (pressure) exp 0 to (pressure) exp -0.25. The degree of the effect is found to depend on the size and the wing-stroke frequency of the insect; the effect is absent in big insects with a medium or high frequency, and more or less present in insects with a small size or with a low frequency. The results are discussed. A theory is constructed using well established physical concepts by considering the wings as acting simultaneously as bodies performing simple harmonic rotary motion and as paddles working against the air. It is assumed that the kinetic energy is destroyed after each single stroke. By making this assumption, the frequency in the energy equation is found to be, within a constant rate of energy output, proportional to the -0.33rd power of the moment of inertia of the wings, and thus agrees very well with the correlation between these factors found experimentally. Further it is found that the aerodynamic work of the wings is in most cases very much smaller than the work done in overcoming the effect of the inertia of the wings. It is negligible in big insects with, a medium or high frequency, but more or less significant in insects with a small size or a low frequency. The magnitude of this effect thus depends, in theory, on the size and the wing-stroke frequency, which entirely agrees with the effect of atmospheric pressure found experirnentally. The inferences drawn from this theory show that (1) the energy economy in a big insect is very wasteful, that (2) the rate of energy output is not greatly varied, that (3) it is profitable for the insect to vary the aerodynamic work of the wings by altering the amplitude rather than the frequency of the stroke, that (4) the distribution of energy in flight is delicately balanced, and that (5) the frequency must be low and the amplitude large in insects of great size and weight, and that a very high frequency and a small amplitude can be afforded only by small insects. Many such observations as have been made in nature agree with these inferences. Furthermore, (6) attempts are made to calculate the muscle efficiency in some insects on the basis of the theory. In Appendix I, the technique used to check and eliminate some sources of error in the methods is described, in Appendix II, an application of tlie theory to derive a law between the wing-stroke frequency and the morphological properties of insects is attempted, and in Appendix III, some laws relating different morphological properties of the wings of insects are described.
Background: Chronic congestive heart failure (CHF) is a complex disease with rising prevalence, compromised quality of life (QoL), unplanned hospital admissions, high mortality and therefore high burden of illness. The delivery of care for these patients has been criticized and new strategies addressing crucial domains of care have been shown to be effective on patients' health outcomes, although these trials were conducted in secondary care or in highly organised Health Maintenance Organisations. It remains unclear whether a comprehensive primary care-based case management for the treating general practitioner (GP) can improve patients' QoL. Methods/Design: HICMan is a randomised controlled trial with patients as the unit of randomisation. Aim is to evaluate a structured, standardized and comprehensive complex intervention for patients with CHF in a 12-months follow-up trial. Patients from intervention group receive specific patient leaflets and documentation booklets as well as regular monitoring and screening by a prior trained practice nurse, who gives feedback to the GP upon urgency. Monitoring and screening address aspects of disease-specific selfmanagement, (non)pharmacological adherence and psychosomatic and geriatric comorbidity. GPs are invited to provide a tailored structured counselling 4 times during the trial and receive an additional feedback on pharmacotherapy relevant to prognosis (data of baseline documentation). Patients from control group receive usual care by their GPs, who were introduced to guidelineoriented management and a tailored health counselling concept. Main outcome measurement for patients' QoL is the scale physical functioning of the SF-36 health questionnaire in a 12-month follow-up. Secondary outcomes are the disease specific QoL measured by the Kansas City Cardiomyopathy questionnaire (KCCQ), depression and anxiety disorders (PHQ-9, GAD-7), adherence (EHFScBS and SANA), quality of care measured by an adapted version of the Patient Chronic Illness Assessment of Care questionnaire (PACIC) and NTproBNP. In addition, comprehensive clinical data are collected about health status, comorbidity, medication and health care utilisation. Discussion: As the targeted patient group is mostly cared for and treated by GPs, a comprehensive primary care-based guideline implementation including somatic, psychosomatic and organisational aspects of the delivery of care (HICMAn) is a promising intervention applying proven strategies for optimal care. Trial registration: Current Controlled Trials ISRCTN30822978.
Background Objects in our environment are often partly occluded, yet we effortlessly perceive them as whole and complete. This phenomenon is called visual amodal completion. Psychophysical investigations suggest that the process of completion starts from a representation of the (visible) physical features of the stimulus and ends with a completed representation of the stimulus. The goal of our study was to investigate both stages of the completion process by localizing both brain regions involved in processing the physical features of the stimulus as well as brain regions representing the completed stimulus. Results Using fMRI adaptation we reveal clearly distinct regions in the visual cortex of humans involved in processing of amodal completion: early visual cortex - presumably V1 - processes the local contour information of the stimulus whereas regions in the inferior temporal cortex represent the completed shape. Furthermore, our data suggest that at the level of inferior temporal cortex information regarding the original local contour information is not preserved but replaced by the representation of the amodally completed percept. Conclusion These findings provide neuroimaging evidence for a multiple step theory of amodal completion and further insights into the neuronal correlates of visual perception.
When one considers the results of social scientific surveys, secularisation in Germany seems to be a more or less linear process of erosion of what is traditionally named religiosity. The percentage of citizens who affirm that they are “religious”, believe in God or otherworldly beings, hope for life after death or participate regularly in the praxis of a religious community has been – by and large – steadily declining for decades. This decline has occurred over the succeeding generations: The younger the generation, the fewer “religious” people in it. But the process of secularisation is apparent not only in this persistent quantitative shrinkage from generation to generation. Above all it also manifests itself – this is the thesis of the article – in the transformation of the habitus formations and contents of faith of the generations. The essence of ongoing secularisation naturally is reflected most clearly in its contemporary state of development which is represented in the youngest adult generation. Therefore the analysis of this generation is particularly interesting for the sociology of religion. But the article does not confine to analyze this generation. After indicating some basic premises of the sociology of generations and the notion of secularisation presupposed in this paper, the succession of generations in Germany is outlined hypothetically, from the so-called generation of ´68 to the youngest adult generation, concluding with some remarks about the progress of secularisation.
The retinoic acid related orphan receptor alpha (RORalpha) regulates the expression of various target genes by binding to specific response elements in their promoter region. RORalpha is an interesting pharmaceutical target since it positively affects several pathophysiological processes of clinical relevance. RORalpha enhances the expression of Apo-AI protein, the major constituent of HDL, which is responsible for the cholesterol transportation. RORalpha notably contributes to the bone mineralization and generation of the extracellular bone matrix, demonstrating its involvement in osteoporosis, and by up-regulating the gene for IKBalpha, RORalpha has anti-inflammatory effects. Moreover, RORalpha is necessary for cerebellar development and the maintenance of the mammalian day-night periodicity governed by the core-clock within the suprachiasmatic nuclei. RORalpha receptors have been reported to bind cholesterol, melatonin, or to function ligand-independent. By monomeric binding to the recognition motif AGGTCA preceded by an A/T-rich sequence (ROR response element, RORE), RORalpha constitutively activates gene transcription. However, RORalpha activity is passively suppressed by its opponents RevErbalpha and RevErbbeta, which both bind to the same target sequence. ...
Many environmental chemicals are suspected of disturbing the human and animal endocrine system. These so-called endocrine disruptors can operate in many ways. The interaction of endocrine disruptive effects that eventually endanger human health is still unclear. However, one of the basic mecha-nisms of endocrine disruption is the inhibition of key enzymes in the hormone metabolism. In this study, we focused on the inhibitory potency of suspected endocrine disrupting compounds on aromatase (P450arom) and 5alpha-reductase (5alpha-Re) activities in human tissue and human cancer cells. Both enzymes are essential for the human sex steroid hormone metabolism. We were able to demonstrate that the organotin compounds tributyltin (TBT) and triphenyltin (TPT) are potent unspecific inhibitors of P450arom and 5alpha-Re activity. Prochloraz and fenarimol inhibited P450arom activity at low concentrations (IC50<2 µM), while 5alpha-Re activity was only impaired at higher concentrations (IC50>10 µM). While the human tissue assay proved to be more practical and sensitive as a screening tool for putative endocrine disruptors, the cell assay reflected partly the situation in vivo. In another experimental series, we investigated the inhibitory effect of TPT on P450arom, 5alpha-Re, 3beta-HSD type 2, 17beta-HSD type 1 and type 3 alone and in combination with the strong antioxidant dithioerythrithol (DTE). TPT inhibited unspecifically all enzymes that were tested. The experiments also showed that DTE is able to compensate the adverse effects of TPT, and that the effectiveness of the compensatory activity of DTE differs among the enzymes investigated. The suppressed 5alpha-Re activity could not be reactivated with DTE. Conceivably, cysteine residues that are responsible for the tertiary and quarternary structure of the enzyme are critical targets for TPT. A human sampling study was undertaken with the COMPRENDO partner in Gdansk. 60 Polish and 15 German blood samples were investigated for chemical residues and sex hormone concentrations. In addition, 15 placenta samples from Poland and Germany, respectively, were tested for chemical residues, P450arom activities and CYP19 mRNA contents. The chemical analysis was performed by the COMPRENDO partners in Milan (p,p´DDE), Orleans (TBT and TPT) and Ioannina (diuron, fenarimol, linuron und vinclozolin). The results showed that individual sex hormone concentrations in blood were not correlated with chemical body burden. The detected differences in sex hormone concentrations, specific aromatase activity and relative CYP19 mRNA content of Polish and German donors were presumably the result of other factors than the ones determined in this study. Another task of the EU-project was the investigation of the effects of chemical exposure of the aquatic model organisms Pimephales promelas, Rutilus rutilus and Xenopus laevis. We investigated the specific P450arom and 5alpha-Re activities in brain and gonads of the animals. During the qualitative investigation of the androgen metabolism in Xenopus laevis brain, 5alpha-reductase activity was discovered for the first time. In contrast to the inhibitory potency of TPT discovered in our enzyme assays, TPT exposure of aquatic model organisms had no observed effect on enzyme activity in the organs investigated, except for P450arom activities in female gonads of Pimephales promelas at 320 ng TPT/L. In this group, mean P450arom activities were elevated, possibly as a result of an overshooting upregulation due to the inhibition of P450arom by TPT. The exposure of Rutilus rutilus and Xenopus laevis to the effector substances methyltestosterone and letrozole resulted in slightly different mean enzyme activities compared to the control group. In conclusion, many of the tested pesticides are able to inhibit P450arom and 5alpha-Re, and thus might be of clinical relevance. However, results are not always coherent, and possible risks for human and wildlife health are therefore difficult to predict. Risk assessment will require large studies with an additional number of short and long term in vitro and in vivo assays. Any extrapolation to humans should be very meticulously performed.
The following thesis is concerned with the elucidation of structural changes of RNA molecules during the time course of dynamic processes that are commonly denoted as folding reactions. In contrast to the field of protein folding, the concept of RNA folding comprises not only folding reactions itself but also refolding- or conformational switching- and assembly processes (see chapter III). The method in this thesis to monitor these diverse processes is high resolution liquid-state NMR spectroscopy. To understand the reactions is of considerable interest, because most biological active RNA molecules function by changing their conformation. This can be either an intrinsic property of their respective sequence or may happen in response to a cellular signal such as small molecular ligand binding (like in the aptamer and riboswitch case), protein or metal binding. The first part of the thesis (chapters II & III) provides a general overview over the field of RNA structure and RNA folding. The two chapters aim at introducing the reader into the current status of research in the field. Chapters II is structured such that primary structure is first described then secondary and tertiary structure elements of RNA structure. A special emphasis is given to bistable RNA systems that are functionally important and represent models to understand fundamental questions of RNA conformational switching. RNA folding in vitro as well as in vivo situations is discussed in Chapter III. The following chapters IV and V also belong to the introduction part and review critically the NMR methods that were used to understand the nature and the dynamics of the conformational/structural transitions in RNA. A general overview of NMR methods quantifying dynamics of biomolecules is provided in chapter IV. A detailed discussion of solvent exchange rates and time-resolved NMR, as the two major techniques used, follows. In the final chapter V of the first part the NMR parameters used in structure calculation and structure calculation itself are conferred. The second part of the thesis, which is the cumulative part, encompasses the conducted original work. Chapter VI reviews the general NMR techniques applied and explains their applicability in the field of RNA structural and biochemical studies in several model cases. Chapter VII describes the achievement of a complete resonance assignment of an RNA model molecule (14mer cUUCGg tetral-loop RNA) and introduces a new technique to assign quaternary carbon resonances of the nucleobases. Furthermore, it reports on a conformational analysis of the sugar backbone in this RNA hairpin molecule in conjunction with a parameterization of 1J scalar couplings. Achievements: • Establishment of two new NMR pulse-sequences facilitating the assignment of quaternary carbons in RNA nucleobases • First complete (99.5%) NMR resonance assignment of an RNA molecule (14mer) including 1H, 13C, 15N, 31P resonances • Description of RNA backbone conformation by a complete set of NMR parameters • Description of the backbone conformational dependence in RNA of new NMR parameters (1J scalar couplings) Chapters VII & VIII summarize the real-NMR studies that were conducted to elucidate the conformational switching events of several RNA systems. Chapter VIII gives an overview on the experiments that were accomplished on three different bistable RNAs. These molecules where chosen to be good model systems for RNA refolding reactions and so consequently served as reporters of conformational switching events of RNA secondary structure elements. Achievements: • First kinetic studies of RNA refolding reactions with atomic resolution by NMR • Application of [new] RT-NMR techniques either regarding the photolytic initiation of the reaction or regarding the readout of the reaction • Discovery of different RNA refolding mechanisms for different RNA molecules Deciphering of a general rule for RNA refolding methodology to conformational switching processes of RNA tertiary structure elements. The models for these processes were a) the guanine-dependent riboswitch RNA and b) the minimal hammerhead ribozyme. Achievements: • NMR spectroscopic assignment of imino-resonances of the hypoxanthine bound guanine-dependent riboswitch RNA • Application of RT-NMR techniques to monitor the ligand induced conformational switch of the aptamer domain of the guanine-dependent riboswitch RNA at atomic resolution • Translation of kinetic information into structural information • Deciphering a folding mechanism for the guanine riboswitch aptamer domain • Application of RT-NMR techniques to monitor the reaction of the catalytically active mHHR RNA at atomic resolution In the appendices the new NMR pulse-sequences and the experimental parameters are described, which are not explicitly treated in the respective manuscripts.
All living organisms exhibit daily fluctuations in biochemical, physiological and behavioural parameters driven by endogenous oscillators, residing in the organism itself. In mammals, the core circadian oscillator is located in the paired suprachiasmatic nuclei (SCN) of the hypothalamus. Circadian rhythm generation in the SCN depends upon the expression of clock genes interacting in positive and negative transcriptional/translational feedback loops. The SCN governs the timing of peripheral circadian oscillators by neuronal pathways and by neuroendocrine mechanisms. An important neuroendocrine hand of the core circadian oscillator is melatonin, which is produced in and secreted from the pineal gland night by night. The adenohypophysis represents a peripheral circadian oscillator and the secretion of one of its hormones, prolactin, is known to be regulated by melatonin. The aim of the present study was to analyze a putative influence of melatonin on the activity state and diurnal variations of identified cell types in the hypophysis. Particular attention was paid to lactotroph, gonadotroph and pars intermedia cells. Experiments were performed with young male mice of different strains: melatonin-proficient C3H, melatonin-deficient C57BL, melatonin-proficient C3H with targeted deletions of the Mel1a receptor (MelaaBB), Mel1b receptor (MelAAbb) or both receptors (Melaabb). Cells producing prolactin (PRL), follicle stimulating hormone (FSH) were immunocytochemically identified and the presence of phosphorylated CREB protein (pCREB) and clock gene protein PER1 was demonstrated by double immunolabeling at different time points during the light/dark cycle in melatonin deficient, melatonin proficient and melatonin receptor knockout mice. Melatonin influence on Prl mRNA levels was investigated by means of in situ hybridization. At night the percentage of lactotroph cells showing a positive nuclear pCREB- and PER1-immunoreaction is significantly smaller in C57BL than in C3H mice. In both mouse strains, the percentage of pCREB –immunoreactive cells is minimal in the early morning and gradually increases to reach a maximum in the late night. PER1 levels show a parallel temporal variation in C3H, but in C57BL, they are drastically reduced in the early afternoon. The percentage of FSH-immunoreactive cells showing pCREB immunoreaction was significantly lower in the melatonin-deficient C57Bl mice than in the melatonin-proficient C3H mice during the second part of the day and during the night. In each strain, the percentage of FSH-immunoreactive cells was lowest at the early morning and gradually increases until the maximum at late night. In wild type (MelAABB) and MelAAbb mice the percentage of lactotroph cells with nuclear pCREB immunoreactions varied significantly over 24 h period, whereas in MelaaBB and Melaabb mice no significant differences were found between the five time points analyzed. The number of Prl mRNA expressing cells was significantly higher in MelaaBB and MelAAbb than in their wild type (MelAABB) littermates. pCREB levels in the pars intermedia did not show rhythmic variation in wild type or Melaabb animals, but wild type mice had higher pCREB levels than Melaabb. The observation that, during darkness, the percentage of lactotroph cells with nuclear pCREB immunoreaction is significantly higher in C3H than in C57BL mice suggests the existence of a distinct cell population that is under the control of melatonin-dependent intrapituitary signaling. Results with melatonin receptor knockout mice indicate that Mel1a and Mel1b melatonin receptors are involved in the control of the activity state of lactotroph cells, but to a differing degree. Analysis of cells expressing Prl mRNA showed that inhibitory action on the Prl expression is mostly mediated through the Mel1a receptor. The significant difference between pCREB immunoreaction in gonadotroph cells of C3H and C57BL mice might suggest that, like lactotrophes, FSH cells represent a heterogeneous population and only a subpopulation is under control of melatonin signaling. The present study is first to show that melatonin signaling also affects pCREB levels in pars intermedia of mice.
To determine the effects of inhaled IL-10 at different doses and different time points on the pulmonary and systemic inflammatory response during endotoxemia, 48 ventilated, anaesthetized rats (mean body weight ± standard deviation, 500 ± 33g) were randomly assigned to six groups (n = 8, each). Interleukin-10 was nebulised either prior to or following the intravenous injection of LPS (5mg/kg) at two doses (5.0 mycro-g or 0.5 mycro-g) in our groups. Eight rats received the same insult with no further treatment (LPS-only group). Another eight rats served as controls without endotoxemia but with aerosolized phosphate-buffered saline, the solvent of IL-10 (Sham group). Concentrations of TNF-alpha, IL-1beta, IL-6, and IFN-gamma were analyzed in plasma and bronchoalveolar lavage fluid (BALF). In addition, the nitrite release from ex-vivo cultured alveolar macrophages was determined. As compared to the LPS-only group, the concentrations of the proinflammatory cytokines TNF-alpha, IL-1beta, IL-6, and IFN-gamma in plasma were significantly reduced in the group, which inhaled 5 mycro-g IL-10 before LPS injection (p< 0.0125). Spontaneous nitrite release from exvivo cultured alveolar macrophages was suppressed in this group (p< 0.0125). Inhalation of 0.5 mycro-g IL-10 before LPS injection and both dosages of IL-10 inhalation (5 mycro-g or 0.5 mycro-g) after LPS injection did not significantly influence either inflammatory cytokine concentrations in BALF, in plasma or the nitrite release from ex-vivo cultured alveolar macrophages. In this study, inhaled IL-10 only demonstrated anti-inflammatory effects when it was administered at 5 mycro-g prior to the induction of experimental endotoxemia. Interleukin-10 aerosol had no effect when it was given either following induction of endotoxemia or given at a lower dosage (which here was 0.5 mycro-g) either before or following injection of lipopolysaccharide.
In several academic fields (most notably: physics, mathematics, economics, astronomy, and computer science), most current research papers are freely accessible on the Internet in both pre- and post-publication formats. For these disciplines, open-access dissemination of publications and data has created a robust and useful information environment that is highly valued by researchers. While the acceptance of open-access dissemination has been disruptive to traditional scholarly publishing, the status and economic value of the elite journals has remained largely intact. Indeed, publication in the most prestigious journals (e.g., Science, Nature, Cell, BMJ, etc.) may have more influence than ever in determining the advancement of academic careers. Traditional publishing and open access will continue to coexist uncomfortably for years to come, but the next wave of digital publishing systems (empowered social networking applications) will establish open access repositories as indispensable infrastructure for the sciences and social sciences.
University 2.0
(2007)
The major challenge facing universities in the next decade is to reinvent themselves as information organizations. Universities are, at their core, organizations that cultivate knowledge, seeking both to create new knowledge and to preserve and convey existing knowledge, but they are remarkably inefficient and therefore ineffective in the way that they leverage their own information resources to advance that core activity. This talk will explore ways that the university could learn from what is now widely called "Web 2.0" -- a term that is meant to identify a shift in emphasis from the computer as platform to the network as platform, from hardware to data, from the wisdom of the expert to the wisdom of crowds, and from fixity to remixability.
Universities of the 21st century heavily depend on an efficient IT infrastructure for teaching, research and administration. E-Learning environments, blended learning and all sorts of multimedia and cooperative environments are important requirements for teaching at universities and for further education. Many of the organizational structures such as continuous examinations, interdisciplinary studies, ECTS system and many more require efficient examination administration systems as well as room and personnel management. Research is based on Internet inquiries, eScience, eLibrary and other IT supported media. Research results must be documented and archived in a digital way and results must be distributed and marketed through the Internet. The efficient administration of all kinds of resources of the university must be planned using management support systems. Decisions of university heads must be prepared from well documented statistics and analysis software. In the past, many of the applications named above for teaching, research and administration have been performed by separate software applications and run in distributed environments of universities. Powerful server structures and networking features as well as new software technology like service-oriented architectures make it necessary to recentralize the IT services of the university after a long period of decentralization. Based on metadirectories and unified access procedures, all of the software components must be integrated into a seamless IT infrastructure. To guarantee consistency, data must not be stored in a redundant way. Project IntegraTUM of Technische Universität München started in 2003 and is an umbrella project to define such a seamless IT infrastructure for a university with 22.000 students and approximately 10.000 staff. The talk describes the project, which besides the definition of new technology is based on a fundamental process analysis of the university and many changes in the organizational structure.
Working closely with teaching and research staff is critical to the success of libraries and information services. Indeed, the degree of integration with a University's academic work is one of the factors that distinguish a successful service from a poor one. This paper will consider the relationship between information services and how universities operate. Using the challenges facing institutions as a starting point - including the move towards a single European higher education market - the impact of information provision on institutional strategies will be explored. Information resources underpin all learning, teaching and research activities and the presentation will consider the professional practice which ensures that libraries and computing services are fully exploited. The focus on the experience of students is leading some institutions to integrate information services with a wide range of other activities and the paper will consider the opportunities and challenges which this brings, including the need to build working relationships with a broader range of professional groups.
Trends for distributed, open, and increasingly collaborative models of information delivery challenge the library's classic roles. In addition, trends within the research community for more interdisciplinary and collaborative scholarship create an opportunity for more enabling information infrastructure. In an age of Amazon, Google, and "social" tools, how should the library respond? My presentation will focus on strategies for bringing the library's "assets" into the flow of researchers' work. How can the library integrate its resources into the scholar's workflow? What are the emerging challenges of this integration?
Information supply is the genuine task of academic institutions as well as of publishers. Publishers profit from copyright provisions which give them exclusive rights in their products. The same copyright provisions are often the limiting factor when academic institutions try to improve their service to the academic community. This is the case in particular when it comes to digital access to information. In a so-called "Second Basket", the German copyright act has just been revised, introducing explicit legal exemptions for document deliveries and on the spot consultation of works contained in public libraries' collections. At the same time, unresolved issues remain with respect to existing legal exemptions as well as the new ones. What will the legal parameters look like for academic institutions once the "Second basket" has been put into force? How can libraries work with these provisions in practice?
Information Supply in the era of mass digitization Drawing on his experience at the Bodleian Library and now at the British Library, Ronald Milne will share his first-hand impressions of 'boutique' and mass digitization programmes, such as those being undertaken by Google and Microsoft, and their effect on information supply. Collections define libraries. What does this mean in the 21st Century? Will all libraries become equal as the digital revolution progresses? What might the digitization and indexing of millions of works mean for university researchers and the intellectually curious more generally? What are the benefits and what are the strategic issues that we are bound to consider?
We survey contributions to the analysis of household liabilities, highlighting relevant theoretical aspects and outlining how data sources may support empirical testing and measurement efforts. Specifically, we classify aspects of household debt, discussing the theoretical and policy relevance of heterogeneity across individual and country dimensions. Aiming to illustrate conceptual and measurement issues, we refer to the approaches and results of some recent relevant country-specific work on administrative and survey data, and we argue that research in this area would greatly benefit from availability of appropriately classified household liabilities data and of cross-country institutional information. JEL Classification: G1, E21
It is theoretically clear and may be verified empirically that efficient financial markets can make it less necessary for policy to try and offset the welfare effects of labour income risk and unequal consumption dynamics. The literature has also pointed out that, since international competition exposes workers to new sources of risk at the same time as it makes it easier for individual choices to undermine collective policies, international economic integration makes insurance-oriented government policies more beneficial as well as more difficult to implement. This paper reviews the economic mechanisms underlying these insights and assesses their empirical relevance in cross-country panel data sets. Interactions between indicators of international economic integration, of government economic involvement, and of financial development are consistent with the idea that financial market development can substitute public schemes when economic integration calls for more effective household consumption smoothing. The paper’s theoretical perspective and empirical evidence suggest that to the extent that governments can foster financial market development by appropriate regulation and supervision, they should do so more urgently at times of intense and increasing internationalization of economic relationships. JEL Classification: G1, E21
We review savings trends in Italy, summarizing available empirical evidence on Italians’ motives to save, relying on macroeconomic indicators as well as on data drawn from the Bank of Italy’s Survey of Household Income and Wealth from 1984 to 2004. The macroeconomic data indicate that households’ saving has dropped significantly, although Italy continues to rank above most other countries in terms of saving. We then examine with microeconomic data four indicators of household financial conditions: the propensity to save, the proportion of households with negative savings, the proportion of households with debt, and the proportion of households that lack access to formal credit markets. By international comparison, the level of debt of Italian households and default risk are relatively low. But in light of the deep changes undergone by the Italian pension system, the fall in saving is a concern, particularly for individuals who entered the labor market after the 1995 reform and who have experienced the largest decline in pension wealth. JEL Classification: D91
Household saving behavior : the role of literacy, information and financial education programs
(2007)
Individuals are increasingly in charge of their own financial security after retirement. But how well-equipped are individuals to make saving decisions; do they possess adequate financial literacy, are they informed about the most important components of saving plans, do they even plan for retirement? This paper shows that financial illiteracy is widespread among the US population and particularly acute among specific demographic groups, such as those with low education, women, African-Americans and Hispanics. Moreover, close to half of older workers do not know which type of pensions they have and the large majority of workers know little about the rules governing Social Security benefits. Lack of literacy and lack of information can affect the ability to save and to secure a comfortable retirement; few individuals rely on the help of financial advisors and ignorance about basic financial concepts can be linked to lack of retirement planning and lack of wealth. Financial education programs can help improve saving and financial decision-making, but much more can be done to improve the effectiveness of these programs. JEL Classification: D91
Recent models with liquidity constraints and impatience emphasize that consumers use savings to buffer income fluctuations. When wealth is below an optimal target, consumers try to increase their buffer stock of wealth by saving more. When it is above target, they increase consumption. This important implication of the buffer stock model of saving has not been subject to direct empirical testing. We derive from the model an appropriate theoretical restriction and test it using data on working-age individuals drawn from the 2002 and 2004 Italian Surveys of Household Income and Wealth. One of the most appealing features of the survey is that it has data on the amount of wealth held for precautionary purposes, which we interpret as target wealth in a buffer stock model. The test results do not support buffer stock behavior, even among population groups that are more likely, a priori, to display such behavior. The saving behavior of young households is instead consistent with models in which impatience, relative to prudence, is not as high as in buffer stock models. JEL Classification: D91
Individuals are increasingly put in charge of their financial security after retirement. Moreover, the supply of complex financial products has increased considerably over the years. However, we still have little or no information about whether individuals have the financial knowledge and skills to navigate this new financial environment. To better understand financial literacy and its relation to financial decision-making, we have devised two special modules for the DNB Household Survey. We have designed questions to measure numeracy and basic knowledge related to the working of inflation and interest rates, as well as questions to measure more advanced financial knowledge related to financial market instruments (stocks, bonds, and mutual funds). We evaluate the importance of financial literacy by studying its relation to the stock market: Are more financially knowledgeable individuals more likely to hold stocks? To assess the direction of causality, we make use of questions measuring financial knowledge before investing in the stock market. We find that, while the understanding of basic economic concepts related to inflation and interest rate compounding is far from perfect, it outperforms the limited knowledge of stocks and bonds, the concept of risk diversification, and the working of financial markets. We also find that the measurement of financial literacy is very sensitive to the wording of survey questions. This provides additional evidence for limited financial knowledge. Finally, we report evidence of an independent effect of financial literacy on stock market participation: Those who have low financial literacy are significantly less likely to invest in stocks. JEL Classification: D91, G11, D80
We consider the advantages and disadvantages of stakeholder-oriented firms that are concerned with employees and suppliers as well as shareholders compared to shareholder-oriented firms. Societies with stakeholder-oriented firms have higher prices, lower output, and can have greater firm value than shareholder-oriented societies. In some circumstances, firms may voluntarily choose to be stakeholder-oriented because this increases their value. Consumers that prefer to buy from stakeholder firms can also enforce a stakeholder society. With globalization entry by stakeholder firms is relatively more attractive than entry by shareholder firms for all societies. JEL Classification: D02, D21, G34, L13, L21
We introduce a multivariate multiplicative error model which is driven by componentspecific observation driven dynamics as well as a common latent autoregressive factor. The model is designed to explicitly account for (information driven) common factor dynamics as well as idiosyncratic effects in the processes of high-frequency return volatilities, trade sizes and trading intensities. The model is estimated by simulated maximum likelihood using efficient importance sampling. Analyzing five minutes data from four liquid stocks traded at the New York Stock Exchange, we find that volatilities, volumes and intensities are driven by idiosyncratic dynamics as well as a highly persistent common factor capturing most causal relations and cross-dependencies between the individual variables. This confirms economic theory and suggests more parsimonious specifications of high-dimensional trading processes. It turns out that common shocks affect the return volatility and the trading volume rather than the trading intensity. JEL Classification: C15, C32, C52
Gastropod molluscs were collected by the author between May and September 1962 from a variety of freshwater habitats in Ethiopia. Twenty-eight forms are represented in the collection of which a total of eleven have not been previously recorded from Ethiopia or have been recorded with doubt by previous authors. Two forms in each of the genera Bulinus and Ancylus appear to be new. It is considered that seven of the forms recorded from Ethiopia for the first time belong to the African component in the fauna, whereas only three are possibly of palaearctic origin. It is concluded that the wide distribution and diversity of some of the palaearctic forms justify the importance attached by Bacci (1951) to the palaearctic element in the molluscan fauna of the Ethiopian Plateau.
Acquiring foreign firms far away might be hazardous to your share price: evidence from Germany
(2007)
This paper examines shareholder wealth effects of cross-border acquisitions. In a sample of 155 large acquisitions by German corporations from 1985–2006 international transactions in total do not lead to significant announcement returns. Geography, however, makes a difference: Shareholders of acquiring firms gain 6.5% in cross-border transactions into countries that have a common border with Germany but lose 4.4% in other international transactions. We find proximity to be one of the most important success factors in cross-border mergers and acquisitions, even when we control for firm, deal and country characteristics.
We analyze the effect of committee formation on how corporate boards perform two main functions: setting CEO pay and overseeing the financial reporting process. The use of performance-based pay schemes induces the CEO to manipulate earnings, which leads to an increased need for board oversight. If the whole board is responsible for both functions, it is inclined to provide the CEO with a compensation scheme that is relatively insensitive to performance in order to reduce the burden of subsequent monitoring. When the functions are separated through the formation of committees, the compensation committee is willing to choose a higher pay-performance sensitivity as the increased cost of oversight is borne by the audit committee. Our model generates predictions relating the board committee structure to the pay-performance sensitivity of CEO compensation, the quality of board oversight, and the level of earnings management.
Mutual insurance companies and stock insurance companies are different forms of organized risk sharing: policyholders and owners are two distinct groups in a stock insurer, while they are one and the same in a mutual. This distinction is relevant to raising capital, selling policies, and sharing risk in the presence of financial distress. Up-front capital is necessary for a stock insurer to offer insurance at a fair premium, but not for a mutual. In the presence of an owner-manager conflict, holding capital is costly. Free-rider and commitment problems limit the degree of capitalization that a stock insurer can obtain. The mutual form, by tying sales of policies to the provision of capital, can overcome these problems at the potential cost of less diversified owners.
The Hindu Buddha according to the theology of the Bengali Vaishnava Acharya Bhaktivedanta Swami
(1999)
In the broad Indian religious culture we find two basic concepts of the inner structure of the Holy. The Advaita religion believes in the 'not-two' will say absolute 'oneness' of the ultimate reality. The Dvaita religion yet believes in 'two' will say the dual structure of the whole. Nevertheless, the latter one is no radical dualism because it recognises nothing to be outside the last reality. It is a kind of 'dualist monism' and insofar fundamentally different to West Asian and European moderate or radical dualism. The Dvaita religion experiences the inner structure of the Holy as everlasting dynamic relation of the whole and its parts. As a rule, the representation of the whole is the personal God, mostly called Bhagavan. The representations of the parts are the soul or jivas. Mostly following the idea the whole being a personal God the Dvaita religion is something like theism; yet, it is an Indian or Hindu theism teaching that the Godhead comprises within herself souls and matter, too. By the way, many of the jivas aren't conscious of their role within the Holy. They erroneously take themselves for empty monads and believe that they would get their realisation only by implementing themselves with 'matter'. Experiencing in this concern the uselessness of matter, the maya energy of the Godhead, they can get the true consciousness of their role as divine co-players in the inner divine play or lila. ...
Castes still determine the social reality of India in many fields and affect politics more and more by functioning as vote banks which are decisive in elections. Thus it is small wonder that there is an ongoing discussion about this social phe-nomenon. The controversies in the course of this discussion not only relate to academic theories concerning the origin, the evolution and the mode of opera-tion of the caste system but also determine the discussion about reform models for the Indian society. Such models either strive for the complete abolition of the caste system or at least call for a comprehensive reform of it. Especially the Dalit movement blames the caste system for the oppression and discrimination of the Dalits in society and tries to withdraw them from this system.[1] Yet the Dalit movement does not develop any alternative social draft. The Hindutva movement makes a strong effort to establish a modern (Hindu) nation which is only possible by overcoming the caste system that totally divides the society. Thus Hindutva is against the caste system though the antagonists of this move-ment usually maintain the contrary.[2] Swami Vivekananda holds that the only way to overcome the caste system is the Brahmanization of the whole society. For this he gives a religious explanation as he announces the end of the Kali-Yuga.[3] The Hare Krishna movement wants to turn away from a hereditary caste system towards a system where every individual is classified according to his skills and performance. Such a system should be based on Vedic traditions and especially on the fourfold varna system which is described in the ancient Rigveda.[4] Gandhi’s social draft and above all its attitude towards the caste system are often part of the current discussion but the interpretations differ according to the inter-preter’s ideological direction. Thus some charge Gandhi with having defended the caste system unconditionally, while others consider him a sharp critic of the system. This large spectrum is hardly surprising, since Gandhi’s comments are very reserved and can only become understandable by a comparative analysis of different statements on the caste system made by him during his political career. This article intends to provide such an analysis without neglecting the historical context which is vital to make Gandhi’s ideas clear. ...
The people of Braj1 are attracted by the Holy in many ways. But nowhere is its attraction per-ceived as strongly as in the public performances of the lilas of Krisna – the lilanukaranas. Although by their aesthetic constitution these dramatic performances are a mixture of song, theater and dance, they do not belong to the genre of folkloric entertainment, for in their very essence they are revelations of the Holy. Thus in Braj the Holy is not at all considered a nirguna entity concealing itself from the world. On the contrary, it reveals itself plainly and unmistakably. This revelation is fully authentic because in its essence the Holy is saguna, i.e. possessed of form. This, however, further means that the lilanukarana do not present something mundane as sacred, nor do they present a 'substitute religion' – for they offer the experience of the Holy moving among and with the lilanukarana, as their equal, freely and naturally, without fear of touch by the creature. And this unconcern for possible worldly contamination allows the Brajbasis to meet the Holy without fear, and in intimate friendship.
The popularity of St. Francis (1182/3-1226) in our days is overwhelming. He has become a modern hero - not only of Catholics but also of Protestants, non-Christians and even atheists. Nevertheless, the question may be raised whether the modern portrayals of St. Francis do justice to the historical person. In order to get a more solid answer we will analyze various documents which were ap-proximately known to and approved by St. Francis himself, particularly his Tes-timony, his Song of Brother Sun, the Unapproved Rule, the Approved Rule, the Admonitions, and the Letter to the Faithful Ones I.[1] We will not even use the legendary reports of his disciples. From the very beginning the devotees of St. Francis made of him a typical convert. This biographic mutilation has remained en vogue until today.[2] - In his Testimony he tells his real story in a few brief words: "While I was in sins it appeared to me extremely bitter to look at the lep-ers. And the Lord himself brought me among them and I gave alms to them. When I was leaving them that what appeared bitter to me was to me exchanged for (converted into) sweetness of the soul and the body. And afterwards I stopped for a moment and then I left the world."[3] Therefore, his life can be divided into three periods: 1) the life in 'sin' or the 'world'; 2) the short period of the conversion, of a short stopping and of the leaving the 'world'; and 3) his exis-tence outside the 'world'. ...
Well before, even centuries before the II Vatican Council there were a lot of theological ac-tivities in India in the context of the different religions, particularly in the context of Hindu-ism. But the Council’s articulations on the Church’s relation with the non-Christian religions gave a tremendous boost to the theological movement in India. Almost all theological reflec-tions in India began to situate themselves in the context of non-Christian religions, especially Hinduism. These theological reflections did not remain solely in the theological circles. They began to trickle down, perhaps hesitantly, into the official ecclesiastical circles. These ele-ments may be considered in the near future by the magisterium of the Church. The reflections in this article are mainly based on: 1. The II Vatican council’s and the post-consiliar magisterium’s teachings on the Church’s relation with the non-Christian religions. 2. "Instrumentum Laboris" which was prepared taking into consideration the theological ac-tivities in Asia, and of course in India, and was published on Feb. 1998, in preparation for the Special Assembly for Asia of the Synod of Bishops. 3. Some of the interventions of the Bishops, especially from India, on the floor of the special assembly held on 19th April to 14th May 1998.
When Lord Caitanya Mahaprabhu was touring South India, He spent the four months during the rainy season called Caturmasya in Shri Rangam at the house of Vyenkata Bhatta, the chief priest of the Ranganatha Temple. His son, Shri Gopala Bhatta, was then able to serve the Lord to his heart's con-tent. Being pleased by his devotion, Shri Caitanya gave him initiation and ordered him to go to Vrin-davana after the disappearance of his parents. There he should remain with Rupa and Sanatana doing bhajana and writing books. - At the age of thirty, after the death of his parents, Gopala Bhatta, left for Vrindavana. When Lord Caitanya heard that Gopala Bhatta Goswami had arrived in Vrindavana and had met Shri Rupa and Sanatana Goswami, He was very pleased. At that time Mahaprabhu had already visited Vrindavana. Although Rupa and Sanatana had gone to visit him in Puri, Gopala Bhatta never received any invitation to go. ...
0. Introduction and theses. 1. Bhaktivedanta Swami's view of Christianity. 1.1. The Bible; 1.2. Jesus; 1.3. History of the church. 2. Bhaktivedanta Swami's religious socialization. 2.1. Childhood; 2.2 College; 2.3. Vaishnava-teachers. 3. Final summary and appendix (with glossary) 0. The Bengal Vaishnava Swami Abhay Caranaravinda Bhaktivedanta, briefly called Bhaktivedanta Swami, lived from 1896 to 1977. Eleven years before his death he founded the International Society for Krishna Consciousness in New York, abbreviated: ISKCON, for the most of you better known as the "Hare-Krishna movement". One may not consider Bhaktivedanta Swami as the founder of a sectarian group, today described as a "new religious movement"; his religion rather is based on a century old, genuine Hindu faith tradition. ...
The word pada-yatra literally means to walk on foot. In early India people used to travel by chariot, horseback, elephant, bullock-cart, or palanquin. But saintly persons, having renounced such worldly comforts, would travel by foot. Their main concern was to teach the glories of God to the conditioned living entities and thereby deliver them from their miserable materialistic lives. Walking was the best means of contacting the common people and accomplishing that goal. When Lord Chaitanya took sannyas - the renounced order of life - He travelled throughout India on foot. First He went from Bengal to Jagannatha Puri in Orissa and then He toured South India on foot of course. At that South India was seriously influenced by impersonalism, and the people in general had deviated from the path of devotion to the Lord. Love of God is the source of real happiness, and when one abandons that loving relationship with God, he suffers. Lord Chaitanya wanted to deliver the conditioned souls plunged in the absolute misery of that impersonalism. In order to reinstate them as devotees of the Lord, Sri Chaitanya went personally to South India. Sri Chaitanya Mahaprabhu is none other than the Supreme Personality of God-head who appeared as a devotee to teach the science of devotion - the only means of deliverance from material bondage. When the Lord performs any ac-tion, its effects are wonderful; similarly, when He directs His devotees to do anything, their result will also be wonderful. Lord Chaitanya's deliverance of South India stands as a proof that He is the Supreme Personality of Godhead in the guise of a devotee. ...
1. Introduction and intentions. 2. Aspects of Christianity. 2.1. Jesus Christ. 2.1.1. Titles; 2.1.2. Character and mission 2.2. The Bible. 2.3. Criticism. 2.4. Bhaktivedanta Swami. 2.4.1. Comparison with Jesus; 2.4.2. Devia-tions. 3. Final summary. 4. Sources 1. Introduction and intentions The Vaishnava News Network (VNN; Internet-address: http://www.vnn.org/) is a "network of collaborating Vaishnavas worldwide providing the world Vaishnava community with news and forums of communication", offering its news service free of charge. Founded in 1997 by an international group of Vaishnavas it calls itself an "independent, comprehensive and universal informa-tion source and communication center". Anyone can participate, i.e. write arti-cles for the VNN which does not censor any news "as long as it conforms with the VNN Standards of Publication." VNN tells the virtual community about the theological background that, "al-though primarily founded by students of A.C.Bhaktivedanta Swami, (it) holds no partiality whatsoever towards any group or divisions of any Vaishnava school" and "is not affiliated, dominated, funded or controlled by any particular Vaishnava organization or group other than its correspondents, senior editors and staff". It is aligned with the philosophical path delineated by their spiritual preceptors in line with the teachings of Sri Chaitanya Mahaprabhu, known as Gaudiya Vaishnavism." In this essay different views of Christianity of several correspondents, senior editors and other staff members of VNN shall be treated. The text sources of the investigation were confined in time to one calendary year (1998). All relevant writings published by VNN can be looked up by means of the VNN internal search engine, concentrating on the key words "Jesus Christ", "Christianity" and "Bible". The results in this piece of work will be compared steadily to the scriptures of the Bengal Swami Abhay Caranaravinda Bhaktivedanta (1896-1977), briefly called "Bhaktivedanta Swami" or with the honorary title "Srila Prabhupada", mainly because of his predominant and fundamental influence on the modern Vaishnava community, not only in the western world of this outgoing 20th cen-tury. Especially Bhaktivedanta Swami's conception of an inter-religious dia-logue with the Christian faith will be taken into consideration. With that the author wants to examine the execution of his plans, the extent of possible changes and the seriousness performed by Bhaktivedanta Swami's pu-pils resp. by ISKCON devotees introduced after his death.
The origin of the religious experience, says Vivekananda, is man's instinctive urge to transcend the sensual world. He believes that man is a compound of two fundamental ele-ments: sense arid mind. While through the senses he receives impressions of the objective world, he cannot remain satisfied with his senses, simply because he wants to go beyond them. Therefore, through his mind, at certain moments he transcends the limitations of the senses. But he also transcends the power of reasoning. He then comes face to face with the facts which he could never have sensed, could never have reasoned out. According to Vivekananda, this fact is the main basis of all the religions of the world. ...
This study is obliged to the "Marburg School of the Science of Religions" (R. Otto, H. Frick, K. Goldammer, E. Benz). The methodological concept follows the comparison of religions, as it is classically demonstrated by R. Otto in his work about "West-östliche Mystik"[1] concern-ing the contrasting of Shankara and Meister Eckhart. That the comparison of the figures of the masters which is practised in this school may yield good results is also proved by G. Mensching, Otto's disciple in Bonn, in his book on "Buddha und Christus - ein Vergleich"[2] and H. Frick, Otto's successor on the Marburg chair in Systematic Theology, in his early trea-tise upon "Ghazalis Selbstbiographie. Ein Vergleich mit Augustins Konfessionen"[3][4]. Spe-cial emphasis should be given to the attempt of F. Heiler who as early as in 1918 contrasts Buddha as a "master of contemplation" to Jesus as a "master of prayer" in his work "Die bud-dhistische Versenkung"[5]. All the mentioned attempts are based on the eminent enquiries in the field of the common history of religions and the psychology of religion as R. Otto's "Das Heilige" [6] and F. Heiler's "Das Gebet"[7]. Worth mentioning is also the comprehensive study of the Marburg church historian and distinguished authority of the Asian religious world, E. Benz, about "Die Vision"[8]. Benz, also a disciple of R. Otto, was a famous re-searcher of mysticism and spiritualism as well (Joachim of Floris, J. Böhme, E. Swedenborg). ...
Martin Luther (1483 - 1546) and Vishvambhara Mishra (1486 - 1533), known as Shri Krishna Caitanya, have been the outstanding representatives of the great west-eastern religious revolution which shattered the hearts of their societies in the 16th century. They were the spiritual revolutionaries of the modern times. The question may very well be raised if and how these two religious reformers on the edge of modern age share theological commonness, even though they lived wide apart and certainly did not know of each other. We will see: Both Martin Luther and Shri Krishna Caitanya have taught the un-conditioned, Free Love viz. Bhakti. Even if they did it in the tradition of the theological context they were born in they produced a new common setting of religion: the destruction of meritoricly bound religion and its substitution by free religion. The worship of God or charity were no more a mean for but the final state of salvation. Their interpretation of this revolutionary religion has lost nothing of its existen-tial meaning, even though having been twisted often enough to indiscernibility or even to the complete opposite - up to the present day. ...
Among the World religions Sikh religion comparatively is young. Numerically also the followers of Sikh religions are not large. According to the Census of India in the grand total of India's population i.e. 6659, 2879, 8491, the total number of Sikhs is 13,078. 146 out of which 8,937.210 are living in the Panjab province of India and the remaining 4,1409936 are scattered in the rest of the country.[1] These figures do not include the Sikhs living in other countries like the U.K., Canada, USA and other Western and Eastern countries. As these fig-ures show percentwise Sikhs are less than 2%, but they are having a special place among their country people an account of their special characteristics i.e. very hard workers, technicalminded, adventurous nature and willing to embrace all kinds of work. Because of their adventurous and enthusiastic nature, today they are found almost all over the world. On account, of visible insignia given by Sikhs' tenth Guru which includes uncut hair (and use of turban) makes the Sikhs' presence felt in any place. - In this brief study of Sikh religion I will be limiting myself only with one area. I will be looking from the historical perspectives how the Sikh religion came into existence and its growth during the period of 1469 AD - 1703 AD. This period is the most important, because - all the development of Sikh religion belongs to this era only. ...
The Indian Neo Buddhism has aroused a movement since the 50s, which propa-gates Buddhism as the top form of the Indo-genous dharma. - The vast majority of that new religious movement belongs to the Dalits [1], people whose en-dogamous communities have been excluded from the varna system [2a] since centuries. The varna system is the traditional hierarchic structure of the relation-ships of those Indian communities who mutually acknowledge themselves as constituent members of their society. These varna jatis established a social class of people devoid of any basic social right. Declared as 'Untouchables' these peo-ple lost all human substance in the eyes of the varna jatis. Yet, that social degra-dation didn't primarily spring from racial, religious or even cultural reasons but from economic ones. When the old Indian agrarian production became a little more productive the division of labour was established as basic structure of the society; but in India the productivity remained on a low level during centuries so that the new non-productive jatis had to keep down the costs of the material pro-duction and the necessary services; they needed cheapest labour.
Weekly "VIVEK" recently conducted a survey of the opinions of its readers. One of the readers wrote, 'I am a devotee of Shri Ram; I belong to a certain caste; the concept of Hindutva may be all right for you; but how is this Hindutva beneficial to my caste?" This question may be regarded as either very basic or childish. It is basic because its answer devolves on the proper concept of Hin-dutva and it is childish because it displays the ignorance of the reader of the fact that Hindutva encompasses the well-being of all the different section of people. A person like me, having imbibed the concept of Hindutva in its totality, would be quick to answer that different casts cannot have any special consideration for them. Hindutva is a casteless concept. In fact the removal of caste consciousness and caste identities is the raison d'etre of Hindutva. Since Hindutva incorporates the well-being of every single Hindu the question of any special consideration of any particular caste does not arise. Of course this is simple for a person like me who is steeped in the Hindutva concept. It may not be so simple for someone who has come up in the present political environment. Serious consideration must be given to Hindutva against the background of pre-sent atmosphere of caste consciousness. This would narrow and finally eliminate the chasm between ideals and practice. Such a chasm would be a great impedi-ment to the general acceptance of true nationalism.
Psoriasis vulgaris is a common and chronic inflammatory skin disease which has the potential to significantly reduce the quality of life in severely affected patients. The incidence of psoriasis in Western industrialized countries ranges from 1.5 to 2%. Despite the large variety of treatment options available, patient surveys have revealed insufficient satisfaction with the efficacy of available treatments and a high rate of medication non-compliance. To optimize the treatment of psoriasis in Germany, the Deutsche Dermatologische Gesellschaft and the Berufsverband Deutscher Dermatologen (BVDD) have initiated a project to develop evidence-based guidelines for the management of psoriasis. The guidelines focus on induction therapy in cases of mild, moderate, and severe plaque-type psoriasis in adults. The short version of the guidelines reported here consist of a series of therapeutic recommendations that are based on a systematic literature search and subsequent discussion with experts in the field; they have been approved by a team of dermatology experts. In addition to the therapeutic recommendations provided in this short version, the full version of the guidelines includes information on contraindications, adverse events, drug interactions, practicality, and costs as well as detailed information on how best to apply the treatments described (for full version, please see Nast et al., JDDG, Suppl 2:S1–S126, 2006; or http://www.psoriasis-leitlinie.de).
Adverse events triggered by non-steroidal anti-inflammatory drugs (NSAIDs) are among the most common drug-related intolerance reactions in medicine; they are possibly related to inhibition of cyclooxygenase-1. Coxibs, preferentially inhibiting cyclooxygenase-2, may therefore represent safe alternatives in patients with NSAID intolerance. We reviewed the literature in a systematic and structured manner to identify and evaluate studies on the tolerance of coxibs in patients with NSAID intolerance. We searched MEDLINE (1966–2006), the COCHRANE LIBRARY (4th Issue 2006) and EMBASE (1966–2006) up to December 9, 2006, and analysed all publications included using a predefined evaluation sheet. Symptoms and severity of adverse events to coxibs were analysed based on all articles comprising such information. Subsequently, the probability for adverse events triggered by coxibs was determined on analyses of double-blind prospective trials only. Among 3,304 patients with NSAID intolerance, 119 adverse events occurred under coxib medication. All adverse events, except two, have been allergic/urticarial in nature; none was lethal, but two were graded as life-threatening (grade 4). The two non-allergic adverse events were described as a grade 1 upper respiratory tract haemorrhage, and a grade 1 gastrointestinal symptom, respectively. In 13 double-blind prospective studies comprising a total of 591 patients with NSAID intolerance, only 13 adverse reactions to coxib provocations were observed. The triggering coxibs were rofecoxib (2/286), celecoxib (6/208), etoricoxib (4/56), and valdecoxib (1/41). This review documents the good tolerability of coxibs in patients with NSAID intolerance, for whom access to this class of drugs for short-term treatment of pain and inflammation is advantageous.
Rather than introducing a new system for global identity management, the University of Freiburg decided to continue with the existing software systems (esp. from HIS), to identify the leading system for each set of data and to mirror the data between the various systems. A clearly defined workflow ensures that changes to data are made only on the relevant "leading" system and then propagated to the other systems. User authentication for systems managed by the computer center is done via LDAP. Consequently, while access rights are granted by the LDAP system, the decision of whether or not the person is a member of the University is left to the administration. As a consequence the implementation of a portal called mylogin to get the necessary tickets for shibboleth is a straightforward process as it only remains to check the data against LDAP before issueing the corresponding tickets.
The historian has to safeguard the strangeness of the past. Therefore, religio-historical research has to scrutinise the reconstruction of the real history of religions by religious ideologies of the present. Very often religious ideologies fall back to the past in order to get an alleged legitimacy for their actual am-bitions; however, for that purpose they have to model or falsify the past according to their present ideo-logical needs. One of the outstanding examples of such an ideologisation of history of religion is the modern view of Buddhism. Developed by the Western colonialist Indology this ideology portrayed and still is portray-ing Buddhism as an rationalist-atheistic, anti-brahmanical, anti-caste and egalitarian religion - in con-trast to Hinduism which is caricatured as idolatrous, casteistic and brahmanised. The aim of such an ideological interpretation is to demonstrate the alleged Western modernity of Buddhism and the alleged obscurantism of Hinduism. The target of that ideological aggression was the Hinduism. In order to exploit the wealth of India the Western colonialists needed the weakening of the Hindu self-consciousness; therefore they favoured an Indology which produced an not existing Indian Buddhism as an alleged modern alternative to the alleged primitive religion of the 'Hindoos'. Playing the Buddhism against the 'Hindoos' the colonialist attempt to defame the vast majority of the Indian people was very successful. Even Indian religious intellectuals and leaders (i.e. the secularists or the Neo-Buddhists1) are sharing and supporting that colonialist view still today. We want to dispute these asserted positions by empirico-historical reasons. First we will discuss the early Buddhism, than Ashoka's reform program of the dharma and at last the historio-graphical dilemmata of scholars sharing the colonialist ideology of Buddhism. ....
First, why I have avoided to use in this paper the expression ‘the Composite Culture’, which even is used in our Constitution of India to describe unified one culture of our country.1 It is because such a demand is not only against one of the basic realities of our Indian way of life, it also goes against the divine will, which was and is behind this created world with different shades and colours. In this regard the following observation made by Dr. Ram Singh is also noteworthy: It is debatable issue whether there is a separate entity called “composite culture” of India, or it is merely the interaction of various cultures which, instead of resulting into an integrated culture, are still in a position to maintain their separate identities. Beside what Dr. Ram Singh says, the reality is that multi or pluralism is part of our Indian or even Asian way of life. It is quite a different thing, if some of us are not willing to accept this truth. But it is still there, in the form of multi-cultures, multi-languages, multireligions and multiethnicities. Therefore the question of ‘composite culture’ is not only debatable, but also a doubtful principle, unless we are willing to take it as an eschatology reality. I do not intend to deal with this point in detail here, because of the time factor. But we may be able to come back to this question of ‘composite culture, in our discussion if you will wish to do so. ...
I would like to begin my presentation with the quotation of the first sentence of Shafii’s Trea-tise er-Risala, the first work which has been reached us until now, concerning foundation of Islamic jurisprudence. “Praise be to God gratitude for one of His favors can only be paid through another favor of him. And this favor generates favor to be bestowed, wherefore, one should feel obliged continuously to pay gratitude to God for each favor.” It is possible to conceive that Mercy (al-Rahma), the common expression of all favors granted by the Almighty Creature of human beings, has two salient characteristics: one is vertical that is with regard to the Creator and creatures, and the other is horizontal that is concerning hu-man relations among themselves as well as with other creatures. When the concept of Mercy is evaluated in perspective of God-human being relations in the existing world, it indicates that God’s favors, without discrimination, are granted to all human beings. ...
As for the relation between Islam and pluralism, it seems a little bit complicated. There are some verses in The Koran for pluralism and at the same time we have some verses against. Among the sayings of Prophet Muhammad like the some Koranic verses, we came across with something good and bad for non-Muslims in special contexts. By another saying, we find both positive and negative statements for Jews and Christians in different circumstances. Muslim scholars the complexity still exists. We find both positive and negative stances. So it is difficult to see a standard or official view on this issue. However, we should point out that Islam recognizes all the sacred (Semitic) books and their messages. It accepts all prophets of that traditions. It defines itself as the last and perfect religion of Semitic tradition and states that no other religion will be accepted from anybody else other then itself. It criticizes both the Jews and Christians especially about their failure to uphold the Oneness of God, tawhid, and to preserve the authenticity of their scripture from interventions. This exclusivist aspect of Islam as many conservative scholars formed with putting together some evidences from the Koran is generally accepted by Muslims.
Religious Anthropology studies the origins, evolution and functions of religions. The discipline researching religious beliefs and rituals comparatively with cross-cultural perspectives tries to enlighten the belief world of the mankind. Religion, as a term, can be defined as "believing as well as worshipping to the supernatural powers and/or beings by the individual who are emotionally or consciously devoted to them" (Örnek 1988: 127). There have been a number of theories so far which try to bring an explanation to the origins and the evolution of religion. In these theories, Fetishism, cults of nature, animism, Totemism, dynamism, Manism, magic, polytheism, monotheism as well as certain physiological phenomena have been particularized as evolutionary stages and forms of belief (Evans-Pritchard 1998: 124). All of these theories have the perspective of so called "progressive" and / or "unilinear" that maintain a religion which has reached ongoing stages and that communities which have developed from primitiveness to civilization. They argue that there has only been one single line of progress, and all of the communities are bound to go through the same evolutionary stages.
Untouchability and inter-caste relations in rural India : the case of southern Tamil villages
(2004)
Justice and equality are the two subjects often talked about by most of the nationalists and leaders of various political and ideological streams across the world including India. India was at the fore-front in condemning racial discrimination particularly apartheid and also the influence of super powers) on the internal affairs of independent nations. Her commitment to secure its citizens' freedom, justice, equality and fraternity is reflected in the very preamble of the Indian Constitution. Towards achieving these challenging goals, special provisions have also been made in the Constitution to protect and promote the interests of the most oppressed section of Indian society - traditionally known as Untouchables and Constitutionally as the Scheduled Castes. These provisions are expected to alter the given unjust distribution of power (political and economic) and status (social) among different sections of people and thereby transform India into an egalitarian society. Given India's unequivocal commitment to secure its citizens these noble ideals - particularly the most exploited and pilloried section of India -, we shall attempt here to understand Indian villages, which host over 80 per cent of the Indian population, from the point of view of whether or not these villages patronise the institution of caste which is in contravention of these ideals or whether there are these little republics ideal for realising the said goals and thus to be preserved as they are as claimed by many social reformers including Mahatma Gandhi. In the process, we shall also address the question of how caste has remained unchanged, how it controls social interaction between higher and lower caste groups and accordingly perpetuates unequal control over power and status. And most importantly we shall also understand whether all the Scheduled Castes (lower castes) treat their members as equals or there is hierarchy, discrimination and practice of untouchability even among them.
Dialogue has become a fashionable word in the theological circles for quite some time now. However, there is a need to review what has been achieved so far. If it is significant, we should then review how much religious tension has been reduced so far. If it is not much, why has there been no progress. In this note I will deal with the issues relating to Hindu-Christian dialogue. I am using Christianity only as a reference point, and the issues raised do have a wider context as well. As far as Hindu-Christian dialogue is concerned, I am of the opinion that there has been hardly any progress all these years. Many academics and theologians have been involved in the exercise so far. The whole literature, over a long period of time, seems to follow a familiar pattern – a discussion on the theory of the dialogue, what should be included in a dialogue, who should and should not be involved in a dialogue, and ends with a lament that there is so very little progress. The problem, according to me, is that the dialogue does not even consider a need to discuss what is the basic difference between Hinduism and Christianity, and an inquiry into whether these come in the way of communal harmony. A dialogue is really not necessary if we are to discuss only what is similar between the two systems. ...
The Dalai Lama, in exile since 1959 in Hindu majority India, has continuously been taking a firm stand on giving importance to an inter-religious dialogue and interaction. He has made it absolutely clear that Buddhism represents just one of the many religious ways open for mankind. Nonetheless, he has always referred to the bond shared between Buddhism and Hinduism as a very special one and has experienced it as a religious tie. Both these religious streams belong to what is known as Bharatiya or Indo-genous Dharma. The Dalai Lama does not restrict his care for nurturing this common bond to a mere academic talk. In fact he has been taking active part in promoting this kind of inter-religious dialogue and has been showing a fiery political commitment as well. He thus took active part in the second World Hindu Congress organized by the Vishwa Hindu Parishad held in Prayag-Allahabad in the year 1979. According to official reports, the organizers in their welcome speech for the Dalai Lama were frank enough to admit that 2500 years ago, the Kashi Pandits (Kashi also known as Varanasi) had stopped Siddharta Gautama Buddha from entering the Vishwanath temple. It was also mentioned that for all these years, there has never been any letup in the conflict between Sanatani Hindus and Bauddhas, despite the fact that later on Shakya Muni was rewarded the status of avatara by Hindus. The fact that these very Kashi Pandits had invite one of the highest religious authorities of Buddhism - the Dalai Lama- to this congress should be seen as "a positive step towards reconciliation." The Dalai Lama was thus pleasantly surprised to see that the highest rung of the religious body of Hindus publicly acknowledged the divine status of Siddharta Gautama Buddha and recognized the presence of the Dalai Lama as a valuable contribution towards the reconciliation between the two religious streams. ...
A fresh look at the understanding of charity : with special reference to the present Indian practice
(2005)
The discussion of this paper is divided in two parts: Present understanding of Charity and a fresh look at the understanding of Charity particularly with a reference to the present Indian practice. As the major religious and theological perspectives specially from the Christian and the Islamic point of views are being dealt by other presentations in this seminar, therefore, the discussion here is limited only first, to the dictionary based linguistic meaning of Charity as understood in three main English speaking contexts and then (second), the Charity as practised in the Indian context. The new and revised deluxe edition of the Webster’s Encyclopaedic Unbridged Dictionary of the English Language has given the following meanings of Charity: 1)charitable actions, as almsgiving or performing other benevolent actions of any sort for the needy with no expectation of material reward: to devote ones life to charity, 2)something given to a person or persons in need; aims: she asked for work not charity, 3) a charitable act or work 4) a charitable fund, foundation, or institution: He left his estate to one of his charities, 5) benevolent feeling, esp. towards those in need or in disfavour: she looked so poor that we fed her out of charity, and 6) Christian love; agape 1 Cor. 13. The Chamber English Dictionary, the meanings of Charity gives as: universal love (N.T.): the disposition to think favourably of others, and do them good almsgiving: a usu. non profit-making foundation, institution, or cause, devoted to caring for those in need of help etc. According to Concise Oxford Dictionary Charity means: an organisation set up to provide help and raise money for those in need, the voluntary giving of money those in need, tolerance in judging others and love of humankind, typically in Christian context. These three set of meanings of Charity, represent the three English regions or contexts: American (Webster), Scottish (Chamber) and English (Oxford). The common important element in all for these three is, the Christian understanding of Charity, because all the three directly have referred to the Biblical usages of Charity in some forms. Here for the discussion of this paper, one can also add that even these usages are limited to the contextual understanding of the English world. Because language is also considered as an vehicle of a culture. But it is true that even the English speaking persons from the non-English world particularly of the Southern countries, (where English rulers have ruled in the past), understand the meaning of Charity more or less in the above sense only. ...
Islam, the Muslim traditions and the ulama in Central Asian societies are becoming increasingly important for assessing the situation in and around the region. To understand of the post Soviet Muslim republics it is nec-essary to know the Islamic heritage of the Soviet Union, i.e. the Islamic understanding and interpretation of Soviet official ulama which still influence the mind of the people and the contemporary Central Asian ulama. The official ulama were endeavouring to reconcile Islam with science and progress and to guarantee its survival in a modern environment, they served by an extremely energetic effort to preserve Islam at least in purity and integrity as religion and national sentiment and to prevent it from relapsing into deprivation and ignorance. The most important official Muslim religious figure, the Mufti of Tashkent Z. Babakhan interpreted Islam as a bulwark of progress, disseminator of knowledge, the religion of peace and friendship; portrayed the Prophet Muhammad as a “democrat, reformer and revolutionary, even a socialist”; reconciliation with socialism and communism.
In this article we dealt with the relations between the state and religion / Islam and its interpreters i.e., the ulama, their needs each other. As a case, with an original source, we focused on the time of the Mahmud II (1808-1839) The Ottoman reforms of the nineteenth century is reconciliation between Islam and Western civili-sation. In this process the ulama played key role by commenting Islam accordance with the need of the age or of the Ottoman Empire. The reformers, chiefly the Sultan and his close friends needed the support of the ulama to legitimate their reform programmes In this crucial stage the head of the ulama the Shaykhulislam, used his own religious knowledge and influence, derived from his office by writing a treatise to persuade the masses to accept the reforms. Applying the traditional virtue literature on the Ottoman dynasty he presented in this pamphlet one of the Western-minded Ottoman sultans as an ideal caliph-sultan. This attitude helped to transform the middle-aged Ottoman political structure and society into modern ages in Western line.
This paper is conceived from a secular perspective, and designed to address three elements identified in the call for papers: “Pluralistic tendencies”, their counterpart of “exclusivist attitudes”, and “creating an ethos of inter-religious harmony”. I choose to tackle these aspects by (a) exploring the meaning of religion, (b) addressing a specific attitude often corresponding to religion, namely religious fervour, and (c) assessing the validity and instrumentality of facilitating a universalist education as a tool to defuse “mistrust and hatred among various faith-communities”. The following paper is intended to serve only as a preliminary discussion guidance paper.
After years and years of persecution, we can say that the continuing and all-embracing revival of church life of the Russian Orthodox Church is going on and the general tendency to the development of all aspects of her diocese, parish and social activities is becoming more and more vivid. There have been some most important events – landmarks of starting the new epoch of Russian Orthodox Church: 1988 – Celebration of the Festival of Thousand Years of Baptizing Rus. 2000 – The Archpriests Council: Canonization of the Tsarist Family of Nicolas II; Attitude to the other Christian Confessions; Social Doctrine of the Russian Orthodox Church. There are 128 dioceses now (instead of 67 ones in 1989) and 19000 parishes (instead of 689 ones in 1989) in the canonical territory of the Russian Orthodox Church. ...
Almost two thousand years ago the question was asked, "And who is my neighbor?", and Jesus answered it with the parable of the Good Samaritan (Luke 10. 29-37), and so the idea of charity was inseparably linked with Christianity. However, it is almost a common opinion that Western Christianity and Russian Orthodoxy have quite different approaches to this item. According to that opinion, the Catholic Church had more concern about one's bodily needs and explicit welfare, while the Russian Orthodoxy paid less attention to the ''explicit man" and took more care of "the inner man". The Russian Orthodox tradition - though it has its own method in ascetism, apotheosis, general and private prayer - pays too little attention to the needy and deprived members of society. To raise the question about mollification of the deprived people's torments and to see it as a way towards the Kingdom of God seems alien to the very essence of Russian Orthodoxy. Did the Russian Orthodox Church ever refuse to help beggars and cripples? Or do the facts still show another picture? Since when did Russian Orthodox Church start to neglect that task? Which reasons have proved that charity has been unable to flourish in the Orthodox Church and especially Russian Orthodox Church as flourished her spirituality and arts: icon painting, choral singing, and church architecture? Let us have a brief outlook on the history of the Russian Orthodox Church and find out if there are any reasons to explain the reason.
This article examines the narratives with regard to lifting the boycott decisions imposed upon the Prophet Muhammad and his companions. There are basically two narratives about this event. While the first one relies on more accurate knowledge, the other contains a speculative scenario. However, since these two narratives were mixed with each other in time, some contradictory information was narrated, especially information based on a speculative scenario became most popular among the people. At the end, it is understood that the document that included the decisions of boycott was not destroyed in a mysterious way, but torn by a group of people.
Our earth, which is a tiny in the infinity of the universe, is getting to be a difficult place to live in. Environmental problems such as pollution and global warming on one side and various disagreements and wars in every corner of the world on the other side, make most of the people unhappy and cause suffering. Everybody living in this world regardless of his or her ethnicity or religion has got share of responsibility to make this earth a place to live in peace and tranquillity. Within this framework, the most important thing in the world is that people with different languages and religious denominations should understand each other better to achieve the goal of creating more secure and peaceful environment for humanity. To make a contribution to this endeavour the Qur’anic guidelines which appear to open a sound way and strengthen the ground of a dialogue between celestial religions should be elucidated.
Living in India, which is not yet linked into the electronic autobahn at quite the screaming pace of the rest of the world, I received my information about this conference in two barely legible faxes, which arrived more than three weeks apart and presented me with two different titles for my paper. The first was "Aspects and Values of Buddhism That Are Attractive to Peoples in the West" and the second was that printed in the conference program, "Aspects and Values of Buddhism for Women in the West." These are rather different topics, but in another way they are not so different. ...
The primary aim in establishing Dolma Ling Institute is to raise the education standard and improve the opportunity for nuns to study advanced Buddhist philosophy and doctrine. During the Tibetan Women's Association fourth working committee meeting in Dharamsala in October, 1992, His Holiness the Dalai Lama said, " In our society , we have as a legacy from the past the notion that nuns engage in ritual only and do not study Buddhist texts. This should be changed." His Holiness has in this way been urging the nuns to study higher Buddhist philosophy, in order to gain a deeper knowledge of Buddhism. Whenever His Holiness visits the Tibetan nunneries, he takes the opportunity to ecourage them to study. Dolma Ling Institute is specifically non sectarian and intented to provide nuns from all lineages with the opportunity to study to develop their full academic and spiritual potential. The crucial purpose of the overall project is to allow scholastically gifted nuns to attain the highest level of religious studies, that is the Geshe degree. This much respected degree has up until now only been attained by monks. Enabling women to participate in the study course leading to this goal will give them the confidence to take on roles as teachers and leaders within the communities. ...
Jetsun Lochen Rinpoche was presumably born in 1865 and died in 1951 and was one of the most famous female religious masters in traditional Tibet. Among her various religious roles were those of pilgrim, professional singer of manis (mani pa), healer, a messenger from the land of the dead (‘das log), yogini, nun, lineage-holder, visionary, performer of miracles (siddha), emanation, treasure-finder, religious teacher and head of a nunnery. In short, she had all the signs and charisma of a holy person. She was popularly known as Jetsun or Ani Lochen (A ne Lo chen), and among her several other names Rigdzin Chönyi Sangmo (Rig ’dzin chos nyid bzang mo) was frequently used. The main textual source regarding Jetsun Lochen Rinpoche’s life is her autobiography (271 folios). Lochen was repeatedly requested by her disciples to tell her life-story, but only in 1937, when she was requested by Drubchen Dawa Dorje Rinpoche (Grub chen Zla ba rdo rje rin po che), whom she recognized as the reincarnation of her root-lama Pema Gyatso (Padma rgya mtsho, 1829-1889/90), did she consent. Although she started telling her life-story in 1937, she abandoned the project and apparently did not take it up again until about twelve years later, in 1949, when she again was requested by Drubchen Dawa Dorje and four named diciples. Lochen told the story of her life up to the 25th day of the 11th month of 1949. The nun-teacher Thinlay (rGan ‘Phrin las) wrote the draft and it was completed by Dawa Dorje Rinpoche. ...
There is no question about charity in Islam: Allah himself has ordered almsgiv-ing: "Narrated Anas bin Malik: … The man further said, 'I ask you by Allah. Has Allah ordered you to take zakat from our rich people and distribute it amongst our poor people?' The Prophet replied, 'By Allah, yes'." The fundamental relevance of Islamic charity, zakat and sadaqa3, roots in the Muslim understanding of God. According to the proper message of Mohammed the first and primary name and quality of God is rahman and rahim4. Allah is - so to speak – rahman, the life giving uterus, rahim. Like the uterus he gives life to the men without any pre-condition. Life is a gift free of charge not a reward for something. ...
Nicotinic acid has been used in the clinical treatment of elevated blood lipid levels for over 50 years. Although it has a beneficial effect on myocardial infarction and blood lipid profiles, its widespread use has been hampered by side effects such as skin rashes and a burning sensation on the upper body. Since elevated blood lipid levels, especially ones of VLDL and LDL cholesterol are a frequent indication and high risk factor for coronary and cardiac diseases, finding a compound with an enhanced pharmacological profile, still holding the desired effects, but without inconvenient side effects, is a very appealing aim to many pharmaceutical companies. These efforts have already produced two marketed drugs, Acipimox and Acifran, but they have not been able to overcome the restrictions already imposed on the treatment by nicotinic acid. Although proposed long before, in the year 2000 the gene for the nicotinic acid receptor in mouse PUMA-G was cloned, and in 2003 the discovery of the genes HM74 and HM74A followed, which comprise the homologous low and high affinity receptors for nicotinic acid in humans. The discovery of this G Protein-coupled receptor target allowed a more directed approach for the search of alternative compounds. This work is the first report of the heterologous overexpression of the high affinity GPCR gene HM74A in the methylotrophic yeast Pichia pastoris. The protein product, NAR1, was pharmacologically characterized, and displayed a binding affinity of 224.8 nM to its ligand nicotinic acid, showing a similar activity profile compared to those displayed in human tissue, which were determined to be 60 nM to 90 nM. Additionally, inhibitory constants (Ki) for Acifran and Acipimox were determined to be 4.5 µM and 50.5 µM, respectively. Furthermore, the total yield of NAR1 reached 42 pmol/mg membrane protein, which corresponds to 0.4 mg of receptor produced per liter yeast culture, opening up the perspective of large scale protein production to facilitate high throughput screening drug discovery efforts and structural studies. In addition, NAR1 could be solubilized in n-decyl-β-D-maltopyranoside and purified to homogeneity after immobilized metal affinity chromatography and a second affinity chromatography step on immobilized monomeric avidin, yielding a single peak on gel filtration, while the purified receptor was able to bind ligand, as shown in NMR Saturation Transfer Difference (STD) measurements. It could be shown that NAR1 is desensitized by β-arrestin 1 in vivo in confocal microscopy studies on HEK and BHK cells. This finding provides a native binding partner for the stabilization of the receptor upon solubilization and purification. Finally human β-arrestin 1 could be produced as a constitutively active variant, comprising residues 1-382 in Pichia pastoris and Escherichia coli. The purified protein was used for in vitro binding experiments and shown to be capable of interacting with NAR1. Although the interaction and formation of the complex was only possible to a limited extent, it leaves open the perspective of crystallizing NAR1 in its active conformation, bound to nicotinic acid and β-arrestin 1.
The goal of this report is to prove correctness of a considerable subset of transformations w.r.t. contextual equivalence in a an extended lambda-calculus with case, constructors, seq, let, and choice, with a simple set of reduction rules. Unfortunately, a direct proof appears to be impossible. The correctness proof is by defining another calculus comprising the complex variants of copy, case-reduction and seq-reductions that use variablebinding chains. This complex calculus has well-behaved diagrams and allows a proof that of correctness of transformations, and also that the simple calculus defines an equivalent contextual order.
Poster presentation Background Single nucleotide polymorphisms (SNPs) of the TNF gene at positions -238 and -308 have earlier been associated with psoriasis vulgaris and psoriatic arthritis (PsA). However, a strong linkage disequilibrium at the chromosomal region 6p21 renders the interpretation of these findings difficult since also other risk factors for psoriasis (PSORS1) than SNPs of the TNF gene have bee mapped to that particular region. Therefore, in this study several SNPs of the TNF gene and of its neighbouring lymphotoxin alpha (LTA) gene were analysed independently and dependently on carrying the PSORS1 risk allele. Methods SNPs in the promoter of the TNF gene (-238G/A, -308G/A, -857C/T, -1031T/C), and one SNP of the LTA gene (+252A/G), of the TNLFRSF1A gene (+36A/G) and of the TNLFRSF1B gene (+676T/G), respectively, were genotyped in 375 psoriasis patients, 375 PsA patients, and 376 controls. The tryptophan–tryptophan–cysteine–cysteine haplotype of the CCHCR1 gene (CCHCR1*WWCC) was used to estimate the genetic impact of the PSORS1 risk allele. Results Whereas an earlier-described association of allele TNF*-238A with psoriasis could be confirmed, our study revealed that this association was completely dependent on concomitant carriage of the PSORS1 risk allele. For PsA, but not psoriasis vulgaris without joint manifestations, strong association with the allele TNF*-857T was detected (OR = 1.956; P value corrected for multiple testing, Pcorr = 0.0025) also in patients negative for the PSORS1 risk allele. Conclusion Our results indicate genetic differences between psoriasis vulgaris patients with and without joint manifestation. While the previously reported association between TNF*-238A and psoriasis seems to primarily reflect linkage disequilibrium with PSORS1, TNF*-857T may represent a risk factor for PsA independent of PSORS1. A potential pathophysiologic relevance of the elucidated genetic association is further suggested by previously reported experimental evidence for a functional impact of the respective TNF polymorphism on TNFalpha expression levels.