Refine
Year of publication
Document Type
- Article (4960)
- Preprint (173)
- Doctoral Thesis (127)
- Conference Proceeding (81)
- Part of Periodical (12)
- Part of a Book (8)
- Book (7)
- Review (4)
- Working Paper (3)
- Report (1)
Language
- English (5376) (remove)
Keywords
- inflammation (80)
- COVID-19 (57)
- SARS-CoV-2 (48)
- glioblastoma (38)
- apoptosis (37)
- cancer (37)
- Inflammation (35)
- prostate cancer (30)
- autophagy (29)
- breast cancer (27)
- Cancer (26)
- biomarker (24)
- immunotherapy (23)
- macrophage (23)
- ADHD (22)
- Apoptosis (22)
- Depression (21)
- Video (20)
- chemotherapy (19)
- epilepsy (19)
- hypoxia (19)
- mitochondria (19)
- pain (19)
- Breast cancer (18)
- aging (18)
- data science (18)
- reactive oxygen species (18)
- Epilepsy (17)
- angiogenesis (17)
- microRNA (17)
- Biomarker (16)
- Quality of life (16)
- Treatment (16)
- children (16)
- depression (16)
- fMRI (16)
- glioma (16)
- Cirrhosis (15)
- Genetics (15)
- Germany (15)
- Neuroscience (15)
- Stroke (15)
- Surgery (15)
- endothelial cells (15)
- proliferation (15)
- radical prostatectomy (15)
- tumor microenvironment (15)
- HIV (14)
- MRI (14)
- Magnetic resonance imaging (14)
- cirrhosis (14)
- cytokines (14)
- obesity (14)
- schizophrenia (14)
- stroke (14)
- Biomarkers (13)
- Capsule endoscopy (13)
- Human behaviour (13)
- Mortality (13)
- NADPH oxidase (13)
- Oncology (13)
- Outcome (13)
- Radiotherapy (13)
- attention (13)
- bladder cancer (13)
- mTOR (13)
- macrophages (13)
- multiple sclerosis (13)
- quality of life (13)
- Angiogenesis (12)
- EEG (12)
- Gene expression (12)
- Immunotherapy (12)
- Machine learning (12)
- Mitochondria (12)
- ROS (12)
- diagnosis (12)
- lung cancer (12)
- prevention (12)
- psoriasis (12)
- survival (12)
- targeted therapy (12)
- Chemotherapy (11)
- Endoscopy (11)
- Heart failure (11)
- Immunology (11)
- cell death (11)
- child (11)
- cognition (11)
- epidemiology (11)
- hepatitis C virus (11)
- integrins (11)
- invasion (11)
- macrophage polarization (11)
- miRNA (11)
- mortality (11)
- outcome (11)
- radiotherapy (11)
- Atrial fibrillation (10)
- COPD (10)
- Diagnostic markers (10)
- Epidemiology (10)
- Hepatocellular carcinoma (10)
- Macrophages (10)
- Parkinson’s disease (10)
- Primary care (10)
- Research article (10)
- Small bowel (10)
- Survival (10)
- colorectal cancer (10)
- coronavirus (10)
- epigenetics (10)
- extracellular matrix (10)
- gene therapy (10)
- infection (10)
- leukemia (10)
- metastasis (10)
- migration (10)
- neuroblastoma (10)
- oxidative stress (10)
- prevalence (10)
- proteomics (10)
- risk factors (10)
- surgery (10)
- treatment (10)
- Autophagy (9)
- Bipolar disorder (9)
- Blood (9)
- Children (9)
- General practice (9)
- Hemorrhage (9)
- PCR (9)
- Pain (9)
- Prostate cancer (9)
- Proteomics (9)
- Schizophrenia (9)
- Suicide (9)
- VEGF (9)
- artificial intelligence (9)
- brain metastases (9)
- complications (9)
- development (9)
- elderly (9)
- human (9)
- innate immunity (9)
- liver (9)
- machine learning (9)
- metabolism (9)
- neurodegeneration (9)
- osteoarthritis (9)
- portal hypertension (9)
- sphingosine-1-phosphate (9)
- vaccination (9)
- ACLF (8)
- Acute myeloid leukemia (8)
- Cardiovascular magnetic resonance (8)
- Diagnosis (8)
- Drug therapy (8)
- Europe (8)
- Hepatitis C virus (8)
- Liver diseases (8)
- Molecular biology (8)
- Multimorbidity (8)
- NASH (8)
- Osteoporosis (8)
- Prognosis (8)
- Seizure (8)
- TAVI (8)
- Trauma (8)
- adhesion (8)
- aortic stenosis (8)
- curcumin (8)
- differentiation (8)
- drug resistance (8)
- fibrosis (8)
- hepatocellular carcinoma (8)
- hereditary angioedema (8)
- magnetic resonance imaging (8)
- monocytes (8)
- p53 (8)
- periodontitis (8)
- physical activity (8)
- polypharmacy (8)
- polytrauma (8)
- therapy (8)
- trauma (8)
- ubiquitin (8)
- Autism spectrum disorder (7)
- Borrelia (7)
- Cell biology (7)
- DNA methylation (7)
- EGFR (7)
- Endothelial cells (7)
- Forensic entomology (7)
- HCV (7)
- HDAC (7)
- Herb induced liver injury (7)
- Hypoxia (7)
- Immunohistochemistry (7)
- Medical research (7)
- Mental health and psychiatry (7)
- NK cells (7)
- Obesity (7)
- PD-L1 (7)
- Patients (7)
- Postural control (7)
- Rheumatoid arthritis (7)
- TRAIL (7)
- antiviral therapy (7)
- atherosclerosis (7)
- biomarkers (7)
- bipolar disorder (7)
- chronic kidney disease (7)
- efficacy (7)
- gender (7)
- gene expression (7)
- heart failure (7)
- hematopoietic stem cell transplantation (7)
- hippocampus (7)
- iron (7)
- liver cirrhosis (7)
- liver transplantation (7)
- machine-learning (7)
- microbiome (7)
- mouse (7)
- multimorbidity (7)
- natural killer cells (7)
- neuropathic pain (7)
- pregnancy (7)
- primary care (7)
- prognosis (7)
- qualitative research (7)
- renal cell carcinoma (7)
- seizure (7)
- sepsis (7)
- sphingolipids (7)
- thrombosis (7)
- toxicity (7)
- working memory (7)
- ATM (6)
- Adenocarcinoma (6)
- Antiviral therapy (6)
- Balloon enteroscopy (6)
- Calliphoridae (6)
- Cancer treatment (6)
- Clinical trial (6)
- Colorectal cancer (6)
- Comorbidity (6)
- Complications (6)
- Crohn’s disease (6)
- Data science (6)
- Death rates (6)
- Diabetes mellitus (6)
- Elderly (6)
- Enteroscopy (6)
- Glioblastoma (6)
- HBV (6)
- Histology (6)
- Hypertension (6)
- Incidence (6)
- Liver transplantation (6)
- Malaria (6)
- Mammakarzinom (6)
- Morbidity (6)
- Multiple sclerosis (6)
- Multivariate analysis (6)
- Neurology (6)
- Non-small cell lung cancer (6)
- Oral anticoagulation (6)
- Outcomes (6)
- PI3K (6)
- Patient blood management (6)
- Pneumonia (6)
- Portal hypertension (6)
- Pregnancy (6)
- Prevalence (6)
- Rare diseases (6)
- Reactive oxygen species (6)
- Rectal cancer (6)
- Risk factors (6)
- Surgical and invasive medical procedures (6)
- T cell (6)
- T cells (6)
- Transfusion (6)
- Translational research (6)
- Viral load (6)
- acute myeloid leukemia (6)
- acute-on-chronic liver failure (6)
- asthma (6)
- atrial fibrillation (6)
- bevacizumab (6)
- cochlear implant (6)
- conduct disorder (6)
- cytotoxicity (6)
- dentate gyrus (6)
- diabetes (6)
- diffusion tensor imaging (6)
- environmental tobacco smoke (6)
- exercise (6)
- exosomes (6)
- fibroblasts (6)
- flow cytometry (6)
- growth (6)
- immunity (6)
- immunohistochemistry (6)
- information theory (6)
- integrin (6)
- iron deficiency (6)
- melanoma (6)
- mesenchymal stromal/stem cells (6)
- microglia (6)
- ovarian cancer (6)
- particulate matter (6)
- platelets (6)
- prophylaxis (6)
- radiation (6)
- resistance (6)
- safety (6)
- signal transduction (6)
- sphingosine 1-phosphate (6)
- stress (6)
- tumor-associated macrophages (6)
- vitamin D (6)
- AML (5)
- Aging (5)
- Anemia (5)
- Anticoagulation (5)
- Aortic stenosis (5)
- Artificial intelligence (5)
- Aspergillus (5)
- Atherosclerosis (5)
- Attention (5)
- Attitude (5)
- Autopsy (5)
- B cells (5)
- Biochemistry (5)
- C-reactive protein (5)
- Cardiovascular diseases (5)
- Cell signalling (5)
- Clinical trials (5)
- Cognition (5)
- Consensus (5)
- Critical care (5)
- Cytokines (5)
- DMEK (5)
- Dopamine (5)
- Drug induced liver injury (5)
- Epigenetics (5)
- Ewing sarcoma (5)
- Exercise (5)
- Experimental models of disease (5)
- Gastric cancer (5)
- Gender (5)
- Gene regulation (5)
- Glioma (5)
- HIV-1 (5)
- HNSCC (5)
- Heart (5)
- Hepatotoxicity (5)
- Herbal hepatotoxicity (5)
- Hippocampus (5)
- Hodgkin lymphoma (5)
- IL-6 (5)
- MEG (5)
- Machine-learning (5)
- Melanoma (5)
- MicroRNAs (5)
- Molecular neuroscience (5)
- Mouse models (5)
- Musculoskeletal system (5)
- NF-κB (5)
- NK cell (5)
- NK-92 (5)
- NKG2D (5)
- Omicron (5)
- Parkinson's disease (5)
- Physical activity (5)
- Physiology (5)
- Platelet-rich fibrin (5)
- Polypharmacy (5)
- Predictive markers (5)
- Prevention (5)
- Prävention (5)
- Psychiatric disorders (5)
- RUCAM (5)
- Radiomics (5)
- Randomized controlled trial (5)
- Rhabdomyosarcoma (5)
- Safety (5)
- Sepsis (5)
- Signaling (5)
- Smac (5)
- Surgical oncology (5)
- Targeted therapy (5)
- Training (5)
- Tumor microenvironment (5)
- Ubiquitination (5)
- Ultrasound (5)
- Vaccination (5)
- Validation (5)
- XIAP (5)
- acute coronary syndrome (5)
- acute lymphoblastic leukemia (5)
- adaptation (5)
- adolescents (5)
- ataxia telangiectasia (5)
- cardiac surgery (5)
- cell therapy (5)
- ceramides (5)
- chimeric antigen receptor (5)
- clinical trial (5)
- colon cancer (5)
- complement (5)
- critical care (5)
- dendritic cells (5)
- dental implant (5)
- dental implants (5)
- diabetes mellitus (5)
- digital medicine (5)
- everolimus (5)
- forensic entomology (5)
- functional magnetic resonance imaging (5)
- graph theory (5)
- guideline (5)
- histology (5)
- hyperglycemia (5)
- influenza (5)
- lipocalin-2 (5)
- liver fibrosis (5)
- lncRNA (5)
- long non-coding RNA (5)
- mTORC1 (5)
- medical students (5)
- meningioma (5)
- metabolomics (5)
- metastases (5)
- mice (5)
- mutual information (5)
- natural killer cell (5)
- outcomes (5)
- overall survival (5)
- patient blood management (5)
- patients (5)
- phosphorylation (5)
- plasticity (5)
- precision medicine (5)
- predictive coding (5)
- preeclampsia (5)
- prostaglandins (5)
- public health (5)
- quantitative MRI (5)
- regeneration (5)
- rhabdomyosarcoma (5)
- rheumatoid arthritis (5)
- sulforaphane (5)
- synaptic plasticity (5)
- systematic review (5)
- transcranial magnetic stimulation (5)
- ubiquitination (5)
- valproic acid (5)
- vector (5)
- 177Lu-PSMA-617 (4)
- 3D printing (4)
- ABCB1 (4)
- ARDS (4)
- Acute inflammation (4)
- Acute lymphoblastic leukemia (4)
- Adhesion (4)
- Age groups (4)
- Alcohol (4)
- Alzheimer's disease (4)
- Alzheimer’s disease (4)
- Angiography (4)
- Animal models (4)
- Aortic valve (4)
- Ascites (4)
- Aspergillus fumigatus (4)
- Ataxia telangiectasia (4)
- Autism (4)
- Bacterial infection (4)
- Behandlung (4)
- Biopsy (4)
- Bladder cancer (4)
- Blood pressure (4)
- Bone density (4)
- Bone marrow (4)
- Brain (4)
- Brain metastasis (4)
- CIK cells (4)
- CRISPR/Cas9 (4)
- CT (4)
- CXCR4 (4)
- Cardiology (4)
- Cardiovascular disease (4)
- Cell staining (4)
- Cell therapy (4)
- Cesarean section (4)
- Chemoradiotherapy (4)
- Chronic kidney disease (4)
- Classification (4)
- Clinical genetics (4)
- Cochlear implant (4)
- Cohort studies (4)
- Computed tomography (4)
- DILI (4)
- DNA damage (4)
- Data processing (4)
- Decision making (4)
- Decorin (4)
- Denosumab (4)
- Density equalizing mapping (4)
- Developmental biology (4)
- Diagnostic medicine (4)
- Dravet syndrome (4)
- ER stress (4)
- Education (4)
- Emotion regulation (4)
- Emotions (4)
- Endoscopic retrograde cholangiopancreatography (4)
- Evaluation (4)
- Everolimus (4)
- Evidence-based medicine (4)
- Extracellular matrix (4)
- Extracellular vesicles (4)
- Fibrosis (4)
- Flow cytometry (4)
- Genetics research (4)
- Guidelines (4)
- HAE (4)
- HCC (4)
- Health care (4)
- Healthcare worker (4)
- Heart transplantation (4)
- Hematology (4)
- Hereditary angioedema (4)
- Homeostasis (4)
- IAP proteins (4)
- In vitro (4)
- Infection (4)
- Innate immunity (4)
- IntelliCage (4)
- Intensive care (4)
- Intensive care units (4)
- Interleukin-6 (4)
- Kinematic analysis (4)
- Knees (4)
- Labor and delivery (4)
- Legs (4)
- Liver cirrhosis (4)
- Liver fibrosis (4)
- Long non-coding RNAs (4)
- Lung failure (4)
- MRSA (4)
- MSD (4)
- Mechanisms of disease (4)
- Medical education (4)
- Medical risk factors (4)
- Metastasen (4)
- Molecular medicine (4)
- Mouse (4)
- Multidetector computed tomography (4)
- Myocardial infarction (4)
- NAFLD (4)
- Neonates (4)
- Neutropenia (4)
- Next-generation sequencing (4)
- Nox4 (4)
- NoxO1 (4)
- Nrf2 (4)
- OSCE (4)
- PSMA (4)
- Patient safety (4)
- Pediatric (4)
- Personalized medicine (4)
- Physicians (4)
- Prediction (4)
- Proliferation (4)
- Prophylaxis (4)
- Psychology (4)
- Pulmonary embolism (4)
- Quantitative MRI (4)
- Registry (4)
- Roussel Uclaf Causality Assessment Method (4)
- STAT3 (4)
- Sex (4)
- Sex differences (4)
- Status epilepticus (4)
- Stem cell (4)
- Stem cells (4)
- Systematic review (4)
- Thrombosis (4)
- Tissue engineering (4)
- acetaminophen (4)
- acute kidney injury (4)
- adverse events (4)
- age (4)
- aggression (4)
- alirocumab (4)
- anaemia (4)
- anemia (4)
- animal model (4)
- antibodies (4)
- antioxidants (4)
- augmentation (4)
- bibliometrics (4)
- bibliometry (4)
- bioinformatics (4)
- brachytherapy (4)
- cGMP (4)
- cancer stem cells (4)
- cardiovascular disease (4)
- cell biology (4)
- cell migration (4)
- cerebrospinal fluid (4)
- cervical cancer (4)
- chemoradiotherapy (4)
- chemoresistance (4)
- cholesterol (4)
- climate change (4)
- clinical study (4)
- combination therapy (4)
- computed tomography (4)
- connectivity (4)
- cortex (4)
- cystic fibrosis (4)
- cytomegalovirus (4)
- dementia (4)
- dentist (4)
- direct-acting antivirals (4)
- doxorubicin (4)
- electroencephalography (4)
- electrolytic cleaning (4)
- entropy (4)
- ergonomics (4)
- external beam radiotherapy (4)
- extracellular vesicles (4)
- fatigue (4)
- general practice (4)
- haemophilia treatment (4)
- health-related quality of life (4)
- heart (4)
- hemodialysis (4)
- hemorrhage (4)
- hepatitis C (4)
- imaging (4)
- immune evasion (4)
- immune response (4)
- impulsivity (4)
- in vitro (4)
- inflammasome (4)
- inflammatory bowel disease (4)
- kidney (4)
- leukocytes (4)
- levetiracetam (4)
- lipoxygenase (4)
- management (4)
- mass spectrometry (4)
- mesenchymal stromal cells (4)
- metabolic syndrome (4)
- metastatic prostate cancer (4)
- motility (4)
- musculoskeletal disorders (4)
- neural oscillations (4)
- nitric oxide (4)
- nociception (4)
- p21 (4)
- pancreatic cancer (4)
- pandemic (4)
- pediatric (4)
- perception (4)
- periimplantitis (4)
- peripheral artery disease (4)
- phagocytosis (4)
- primary cilium (4)
- primary immunodeficiency (4)
- proteome (4)
- psoriatic arthritis (4)
- questionnaire (4)
- rapamycin (4)
- registry (4)
- simulation training (4)
- smoking (4)
- spirochetes (4)
- status epilepticus (4)
- temozolomide (4)
- temporal lobe epilepsy (4)
- thrombolysis (4)
- thymus (4)
- tissue engineering (4)
- tooth loss (4)
- transfusion (4)
- transplantation (4)
- traumatic brain injury (4)
- treatment centres (4)
- tumor growth (4)
- tumor progression (4)
- vaccine (4)
- wound healing (4)
- (surface) partial differential equations (3)
- 3D rapid prototyping (3)
- ADAM15 (3)
- Acute kidney injury (3)
- Adults (3)
- Adverse events (3)
- Amblyopia (3)
- Antibiotics (3)
- Antibodies (3)
- Antiretroviral therapy (3)
- Anxiety (3)
- Aortic valve replacement (3)
- Ataxia-telangiectasia (3)
- B-cell lymphoma (3)
- BAG3 (3)
- BCR/ABL (3)
- BMC (3)
- BMI (3)
- BRAF (3)
- BRD4 (3)
- Behavior (3)
- Bibliometrics (3)
- Blood-brain barrier (3)
- Bone defect (3)
- Bone regeneration (3)
- Bone tissue engineering (3)
- Brain tumor (3)
- Burden of illness (3)
- C. elegans (3)
- C1 inhibitor (3)
- CAD/CAM (3)
- CAR (3)
- CD36 (3)
- CDK4/6 (3)
- COMP (3)
- CRM (3)
- CRP (3)
- CTGF (3)
- CXCL12 (3)
- CXCR3 (3)
- Calcium (3)
- Cancer chemotherapy (3)
- Cancer detection and diagnosis (3)
- Cancer genetics (3)
- Cancer genomics (3)
- Candida (3)
- Cannabis (3)
- Cardiac surgery (3)
- Case report (3)
- Catheter ablation (3)
- Cell proliferation (3)
- Cerebellum (3)
- Cerebrospinal fluid (3)
- Chaperone (3)
- Child (3)
- Chromatin accessibility (3)
- Chronic hepatitis C (3)
- Citation analysis (3)
- Clinical Trials and Observations (3)
- Clinical decision support systems (3)
- Cognitive impairment (3)
- Cognitive neuroscience (3)
- Collagen (3)
- Complex I (3)
- Computer software (3)
- Computer-assisted diagnosis (3)
- Conduct disorder (3)
- Connective tissue (3)
- Coronary heart disease (3)
- Costs (3)
- Cytoskeleton (3)
- DAA (3)
- DNA mismatch repair (3)
- DNase1-seq (3)
- DTI (3)
- Deep brain stimulation (3)
- Dental implant (3)
- Dental students (3)
- Dose response (3)
- Drug hepatotoxicity (3)
- Drug resistance (3)
- ECMO (3)
- EEG microstates (3)
- Eccentric fixation (3)
- Edema (3)
- Efficiency (3)
- Ejection fraction (3)
- Endocrinology (3)
- Endothelium (3)
- European Union (3)
- Exosomes (3)
- Eyes (3)
- FFLU (3)
- FTY720 (3)
- Fasting (3)
- Feedback (3)
- Fibronectin (3)
- Fingolimod (3)
- Finite Volumes (3)
- Fistula (3)
- Functional clustering (3)
- G-CSF (3)
- GPCR (3)
- Gene Regulation (3)
- Gene fusion (3)
- Gene therapy (3)
- Genome-wide association studies (3)
- Global health (3)
- HER2 (3)
- HER2/neu (3)
- HPV (3)
- HSCT (3)
- Head and neck cancer (3)
- Healthcare costs (3)
- Healthy adults (3)
- Hepatitis C (3)
- HoLEP (3)
- Hospitals (3)
- Human genetics (3)
- IAPs (3)
- IBD (3)
- IL-1β (3)
- Immune cells (3)
- Induction chemotherapy (3)
- Infections (3)
- Inflammatory bowel disease (3)
- Inflammatory diseases (3)
- Interleukin (3)
- Interleukin-22 (3)
- Ischemia (3)
- Kidney transplantation (3)
- Knowledge (3)
- LCMV (3)
- LPS (3)
- Langerhans cell histiocytosis (3)
- Language (3)
- Lesions (3)
- Liver Transplantation (3)
- LncRNA (3)
- Lumbar spine (3)
- Lyme disease (3)
- MCAK (3)
- MLL (3)
- MYC (3)
- Macrophage polarization (3)
- Major depressive disorder (3)
- Masquelet technique (3)
- Mass spectrometry (3)
- Memory (3)
- Mental health (3)
- Mesenchymal stem cells (3)
- Messenger RNA (3)
- Metabolic diseases (3)
- Metabolomics (3)
- Microbiology (3)
- Microbiome (3)
- Microwave ablation (3)
- Migration (3)
- Mitochondrial dysfunction (3)
- Mitosis (3)
- Morphogenesis (3)
- Motor control (3)
- Multianalyte detection (3)
- Musculoskeletal disorder (3)
- NADH dehydrogenase (3)
- NSCLC (3)
- Neurodegeneration (3)
- Neuroinflammation (3)
- Neurotransmitter (3)
- Nitric oxide (3)
- Nivolumab (3)
- Non-coding RNA (3)
- Nox (3)
- OXA-48 (3)
- Observational study (3)
- Occlusion treatment (3)
- PARK2 (3)
- PD1/PDL1 (3)
- PDGFRβ (3)
- Pandemic (3)
- Pathogenesis (3)
- Pediatric patients (3)
- Penile carcinomas (3)
- Peri-implantitis (3)
- Phagocytosis (3)
- Pharmacology (3)
- Phosphorylation (3)
- Platelets (3)
- Podospora anserina (3)
- Portal veins (3)
- Pre-analytics (3)
- Preclinical research (3)
- Preterm birth (3)
- Primary health care (3)
- Prognostic markers (3)
- Progranulin (3)
- Protease inhibitor therapy (3)
- Psoriasis (3)
- Public health (3)
- Pulmonary hypertension (3)
- Questionnaire (3)
- RCT (3)
- RITA (3)
- RNA (3)
- RNA therapeutics (3)
- Reaction time (3)
- Registries (3)
- Regression analysis (3)
- Rehabilitation (3)
- Renal cell carcinoma (3)
- Research Article (3)
- Resistenz (3)
- Respiration (3)
- S1P (3)
- SARS (3)
- SUMO (3)
- Sarcoma (3)
- Screening (3)
- Senescence (3)
- Sensitivity (3)
- Simulated patients (3)
- Sleep (3)
- Spine (3)
- Sport (3)
- Sports and exercise medicine (3)
- Squamous cell carcinoma (3)
- Statistical data (3)
- Stereotactic body radiation therapy (3)
- Studien (3)
- Sudden cardiac death (3)
- Surgeons (3)
- Surveillance (3)
- TGF-β (3)
- TIPS (3)
- TKI (3)
- Tacrolimus (3)
- Telemedicine (3)
- Temozolomide (3)
- Therapy (3)
- Thoracic trauma (3)
- Torque (3)
- Toxicity (3)
- Transarterial chemoembolization (3)
- Transcription factors (3)
- Treatment outcome (3)
- Type 2 diabetes (3)
- Undergraduate medical education (3)
- Upper body posture (3)
- Variant histology (3)
- Wound healing (3)
- Zika virus (3)
- Zoonosis (3)
- acute coronary syndromes (3)
- acute decompensation (3)
- adenosine (3)
- adjuvant chemotherapy (3)
- aged (3)
- ageing (3)
- albumin (3)
- alcohol (3)
- alcohol use disorder (3)
- allogeneic stem cell transplantation (3)
- alveolar ridge augmentation (3)
- anal cancer (3)
- animal (3)
- animal models (3)
- anti-angiogenic therapy (3)
- antiviral (3)
- arteriogenesis (3)
- ascites (3)
- astrocytes (3)
- autism spectrum disorder (3)
- bacteria (3)
- behavior (3)
- bioenergetics (3)
- bleeding (3)
- blood (3)
- blood transfusion (3)
- body mass index (3)
- bone (3)
- bone regeneration (3)
- bortezomib (3)
- brain imaging (3)
- brain metastasis (3)
- burden of illness (3)
- cAMP (3)
- calretinin (3)
- cancer immunotherapy (3)
- cancer specific survival (3)
- carbapenemases (3)
- cardiac (3)
- caregivers (3)
- cartilage (3)
- caspase-2 (3)
- caspase-8 (3)
- catheter ablation (3)
- cell cycle (3)
- cerebellum (3)
- chemokines (3)
- chronic myeloid leukemia (3)
- cisplatin (3)
- classical Hodgkin lymphoma (3)
- clinical research (3)
- clinical trials (3)
- clock genes (3)
- co-infection (3)
- collagen (3)
- comorbidity (3)
- complexome profiling (3)
- computational virology (3)
- confinement (3)
- cortisol (3)
- cytokine-induced killer cells (3)
- dental education (3)
- dental profession (3)
- dexamethasone (3)
- diabetic nephropathy (3)
- diagnostic algorithm (3)
- dopamine (3)
- drug discovery (3)
- drug induced liver injury (3)
- echocardiography (3)
- electrophysiology (3)
- endocannabinoids (3)
- endoplasmic reticulum (3)
- epidermal growth factor receptor (3)
- event-related potentials (3)
- executive function (3)
- fenfluramine (3)
- focal adhesion (3)
- follow-up (3)
- functional connectivity (3)
- functional outcome (3)
- gamma (3)
- gastric cancer (3)
- gene regulation (3)
- glycolysis (3)
- growth inhibition (3)
- haemophilia care (3)
- head and neck cancer (3)
- healthcare worker (3)
- heart rate (3)
- hematopoietic stem and progenitor cells (3)
- hepatitis B (3)
- hepatitis C virus (HCV) (3)
- herb induced liver injury (3)
- histone acetylation (3)
- hyperactivity (3)
- immune cells (3)
- immune checkpoint inhibitors (3)
- immune escape (3)
- immune reconstitution (3)
- immunology (3)
- inertial motion capture (3)
- insulin resistance (3)
- interleukin-22 (3)
- invasive fungal disease (3)
- invasive fungal infection (3)
- iron metabolism (3)
- irradiation (3)
- kidney transplantation (3)
- leptin (3)
- lipids (3)
- liver injury (3)
- lockdown (3)
- long-term prophylaxis (3)
- lung function (3)
- lyme disease (3)
- lymphoma (3)
- mRNA (3)
- magnetoencephalography (3)
- massively parallel multigrid solvers (3)
- mathematical modeling (3)
- memory (3)
- metformin (3)
- miRNAs (3)
- microwave ablation (3)
- mild cognitive impairment (3)
- mitochondrial disease (3)
- mitophagy (3)
- mitosis (3)
- modeling (3)
- molecular mechanisms (3)
- monitoring (3)
- mouse model (3)
- multidrug resistance (3)
- multiple myeloma (3)
- mycophenolic acid (3)
- necroptosis (3)
- neoadjuvant therapy (3)
- neonate (3)
- neoplasms (3)
- neurocritical care (3)
- neuroimaging (3)
- neutralization (3)
- neutralizing antibodies (3)
- next-generation sequencing (3)
- non-coding RNA (3)
- observational study (3)
- oncology (3)
- osteoporosis (3)
- overweight (3)
- oxidative phosphorylation (3)
- p47phox (3)
- patient safety (3)
- pediatric patients (3)
- pentose phosphate pathway (3)
- perforant path transection (3)
- perfusion (3)
- peri-implantitis (3)
- pharmacodynamics (3)
- plasmid (3)
- pneumonia (3)
- prefrontal cortex (3)
- primary health care (3)
- primary prostate cancer (3)
- prostaglandin (3)
- proteoglycan (3)
- pulmonary hypertension (3)
- radical prostatecomy (3)
- rat (3)
- realistic geometries (3)
- receptor (3)
- remodelling (3)
- renal cell cancer (3)
- renal function (3)
- reproducibility (3)
- resting state (3)
- review (3)
- rituximab (3)
- salvage therapy (3)
- screening (3)
- seizures (3)
- senescence (3)
- serum (3)
- severe acute respiratory syndrome coronavirus 2 (3)
- sex (3)
- sex differences (3)
- signaling (3)
- skeletal muscle (3)
- sleep (3)
- soft tissue sarcoma (3)
- sphingolipid (3)
- spinal cord (3)
- stem cell transplantation (3)
- strength training (3)
- stress response (3)
- supportive periodontal therapy (3)
- surgical procedures (3)
- systematic biopsy (3)
- systemic antibiotics (3)
- therapeutics (3)
- tobacco prevention (3)
- toll-like receptor (3)
- transcription factor (3)
- transcriptome (3)
- transient elastography (3)
- tyrosine kinase inhibitor (3)
- tyrosine kinase inhibitors (3)
- ultrasound (3)
- vemurafenib (3)
- viral dynamics (3)
- working conditions (3)
- yeast (3)
- 3D spatio-temporal resolved mathematical models (2)
- 5-lipoxygenase (2)
- A/D transition (2)
- ABCC1 (2)
- ABCG2 (2)
- ACL (2)
- AIDS (2)
- AKI (2)
- ALK (2)
- ALL (2)
- AMPK (2)
- ATP (2)
- ATP-citrate lyase (2)
- Abort (2)
- Academic medicine (2)
- Access (2)
- Accidental reaction (2)
- Acinetobacter baumannii (2)
- Acoustics (2)
- Activities of daily living (2)
- Acuris (2)
- Acute Myeloid Leukemia (AML) (2)
- Acute decompensation (2)
- Acute lymphocytic leukaemia (2)
- Acute myeloid leukaemia (2)
- Acute-on-chronic liver failure (2)
- Addiction (2)
- Addison’s disease (2)
- Adherence (2)
- Adipose tissue (2)
- Adipose-derived mesenchymal stem cells (2)
- Adolescents (2)
- Adult neurogenesis (2)
- Adverse drug reaction (2)
- Aedes aegypti (2)
- Aedes albopictus (2)
- Age estimation (2)
- Akaike information criterion (AIC) (2)
- Alcohol consumption (2)
- Alcoholic liver disease (2)
- Algorithms (2)
- Alleles (2)
- Allergen avoidance (2)
- Allergic asthma (2)
- Allergy (2)
- Allosteric inhibition (2)
- Alzheimer (2)
- Anaemia (2)
- Anal cancer (2)
- Analgesia (2)
- Anandamide (2)
- Anatomy (2)
- Animal model (2)
- Anti-IgE (2)
- Anticoagulant therapy (2)
- Antimicrobial treatment (2)
- Antiretrovirals (2)
- Aortic dissection (2)
- Apheresis (2)
- Apixaban (2)
- Arrhythmia (2)
- Asphyxia (2)
- Assessment (2)
- Ataxia (2)
- Attention-deficit/hyperactivity disorder (2)
- Auditory system (2)
- Aurora A (2)
- Austria (2)
- Autoimmunity (2)
- Autologous biomaterial (2)
- BA.1 (2)
- BCL2 (2)
- BCL6 (2)
- BCOR (2)
- BCX7353 (2)
- BDNF (2)
- BMNC (2)
- BNT162b2 (2)
- BPH (2)
- BRCA1 (2)
- BRCA2 (2)
- Babesia divergens (2)
- Babesia microti (2)
- Benefit (2)
- Bevacizumab (2)
- Big Five (2)
- Biglycan (2)
- Bile duct stone (2)
- Biofilm (2)
- Bioinformatics (2)
- Biomedical informatics (2)
- Biophysical models (2)
- Biorecognition strategies (2)
- Biosynthetic mesh (2)
- Birth weight (2)
- Bleeding (2)
- Blood groups (2)
- Blood loss (2)
- Blood loss estimation (2)
- Blood plasma (2)
- Bloodstream infections (2)
- Blow flies (2)
- Body mass index (2)
- Body modification (2)
- Bone marrow aspiration (2)
- Bone marrow-derived mesenchymal stem cells (2)
- Borrelia burgdorferi (2)
- Breast neoplasms (2)
- Breast tumors (2)
- Burden of disease (2)
- CAM (2)
- CBA (2)
- CC16 (2)
- CCL2 (2)
- CD14 (2)
- CD16 (2)
- CD19 (2)
- CD44 (2)
- CDK9 (2)
- CDKN1A (2)
- CIOMS (2)
- CLP (2)
- CMR (2)
- COVID 19 (2)
- COVID-19 surveillance (2)
- CPE (2)
- CRISPR/Cas (2)
- CSM (2)
- CTLA-4 (2)
- CUELA (2)
- CV9202 (2)
- Callous-unemotional traits (2)
- Calpain (2)
- Cancer epidemiology (2)
- Cancer models (2)
- Cancer therapy (2)
- Cancer-specific mortality (2)
- Cannabidiol (2)
- Capecitabine (2)
- Cardiac arrest (2)
- Cardiac hypertrophy (2)
- Cardiac magnetic resonance (2)
- Cardioprotection (2)
- Cardiovascular biology (2)
- Case management (2)
- Cats (2)
- Causality assessment (2)
- Celiac disease (2)
- Cell binding (2)
- Cell culture (2)
- Cell death (2)
- Cell death and immune response (2)
- Cell differentiation (2)
- Cell division (2)
- Cell salvage (2)
- Checkpoint inhibitor (2)
- Chemical biology (2)
- Chemokines (2)
- Cholangiography (2)
- Cholangiopancreatography (2)
- Chondrocytes (2)
- Chronic disease (2)
- Chronic hepatitis (2)
- Chronic inflammation (2)
- Chronic obstructive pulmonary disease (2)
- Clinical Global Impression of Change (2)
- Clinical presentation (2)
- Clinical studies (2)
- Clinical study (2)
- Cocaine (2)
- Cochlear implantation (2)
- Cognitive behavioral therapy (2)
- Colloids (2)
- Colonoscopy (2)
- Communication (2)
- Community based intervention (2)
- Community health services (2)
- Comorbidities (2)
- Comparative analysis (2)
- Compliance (2)
- Complication management (2)
- Computational models (2)
- Computed Tomography (2)
- Computer hardware (2)
- Computer science (2)
- Connectivity (2)
- Corona (2)
- Coronary artery disease (2)
- Cortex (2)
- Cost-effectiveness (2)
- Covid-19 (2)
- Cre-recombinase (2)
- Croatia (2)
- Crohn's disease (2)
- Cryoelectron microscopy (2)
- Crystal structure (2)
- CspZ (2)
- Cuela (2)
- CyberKnife robotic radiosurgery (2)
- CysLTR1 (2)
- Cystic fibrosis (2)
- Cytogenetics (2)
- Cytologie (2)
- Cytoskeletal proteins (2)
- DMARDs (biologic) (2)
- DNA damage response (2)
- DSM (2)
- Daptomycin (2)
- Data visualization (2)
- Decision (2)
- Decision trees (2)
- Degradation (2)
- Dengue (2)
- Density-equalizing mapping (2)
- Dental implants (2)
- Dentist (2)
- Dentistry (2)
- Deutschland (2)
- Development (2)
- Diabetes (2)
- Diagnose (2)
- Diagnostic algorithm (2)
- Diagnostic imaging (2)
- Diagnostic test (2)
- Differential diagnosis (2)
- Differentiation (2)
- Digestive system procedures (2)
- Direct current electrical stimulation (2)
- Directly acting antiviral agent (2)
- Disease Activity (2)
- Diseases (2)
- Disintegration (2)
- Distance to water (2)
- Docetaxel (2)
- Double-balloon enteroscopy (2)
- Drug development (2)
- Drugs (2)
- Dynamic MRI (2)
- E3 ligase (2)
- EEG-fMRI (2)
- EET (2)
- ELISA (2)
- EMT (2)
- ENCODE-DREAM in vivo Transcription Factor binding site prediction challenge (2)
- EQ-5D (2)
- ERP (2)
- ESBL (2)
- EWSR1 (2)
- Ears (2)
- Edoxaban (2)
- Efficacy (2)
- Electrical stimulation (2)
- Electroencephalography (2)
- Electrophysiology (2)
- Elevation (2)
- Empathy (2)
- Encephalopathy (2)
- EndMT (2)
- Endocannabinoid (2)
- Endocannabinoids (2)
- Endoscopic retrograde (2)
- Endoscopic ultrasound (2)
- Endothelial permeability (2)
- Ensemble learning (2)
- Enterobacteriaceae (2)
- Enterscopy (2)
- Entscheidungsassistenz (2)
- Entzündung (2)
- Environmental support (2)
- Enzyme-linked immunoassays (2)
- EphB4 (2)
- Epicutaneous immunotherapy (2)
- Epidemiology and End Results (2)
- Epidermal growth factor receptor (2)
- Epileptic seizures (2)
- Epileptische Anfälle (2)
- Epstein-Barr virus (2)
- Equity (2)
- Ergonomics (2)
- Etiology (2)
- Evidence-based dentistry (2)
- Extended donor criteria (2)
- Extracellular matrix proteins (2)
- Eye movements (2)
- FEV1 (2)
- FFPE (2)
- FGFR (2)
- FHIR (2)
- Face (2)
- Family practice (2)
- Fatty liver (2)
- Feasibility (2)
- Fibroblasts (2)
- Flaps (2)
- Forensic medicine (2)
- Frailty (2)
- Frühgeburt (2)
- Fuchs endothelial dystrophy (2)
- Function (2)
- Functional characterization (2)
- Functional connectivity (2)
- Functional electrical stimulation (2)
- Functional magnetic resonance imaging (2)
- G2A (2)
- GEMs (2)
- GFAP (2)
- GWAS (2)
- Gadobutrol (2)
- Gait analysis (2)
- Gastritis (2)
- Gastrointestinal bleeding (2)
- Gene ontology (2)
- General practitioners (2)
- Genetic testing (2)
- Geographic variation (2)
- Geographically weighted regression (GWR) (2)
- Geriatric patients (2)
- German people (2)
- Glaucoma (2)
- Gleason score (2)
- Glucose (2)
- Glucose metabolism (2)
- Glycolysis (2)
- Grafts (2)
- Growth factors (2)
- Guideline (2)
- H1N1 (2)
- HCMV (2)
- HDACi (2)
- HIF (2)
- HIV protease inhibitors (2)
- HL7 FHIR (2)
- HOD (2)
- HSV (2)
- HSV-1 (2)
- Health care workers (2)
- Health economics (2)
- Health policy (2)
- Health services (2)
- Health services research (2)
- Healthcare resource utilization (2)
- Hematologic malignancies (2)
- Hemodynamics (2)
- HepG2 (2)
- Hepatitis (2)
- Hepatocytes (2)
- Heterogeneity (2)
- High oblique sagittal osteotomy (2)
- High-density lipoprotein (2)
- Histologie (2)
- Holmes tremor (2)
- Hospital (2)
- ICD (2)
- ICU (2)
- IDH mutation (2)
- IHC (2)
- IL-10 (2)
- IL-12 (2)
- IL-33 (2)
- IR-A (2)
- ISR (2)
- Identification (2)
- Image analysis (2)
- Image processing (2)
- Immunchemie (2)
- Immune suppression (2)
- Immune system (2)
- Immunity (2)
- Immunogenicity (2)
- Immunologie (2)
- Immunosuppression (2)
- Immunsystem (2)
- Implementation (2)
- In vivo (2)
- Incidence rate (2)
- Incisional hernia (2)
- Indirect-binding (2)
- Indonesia (2)
- Infection control (2)
- Infectious diseases (2)
- Influenza (2)
- Information theory (2)
- Injuries (2)
- Injury (2)
- Innate Immunity (2)
- Insulin (2)
- Insulin signalling (2)
- Integration (2)
- Integrin (2)
- Intensive care treatment (2)
- Interferon (2)
- Interleukin-1 (2)
- Internet (2)
- Iron (2)
- Iron deficiency (2)
- Iron deficiency anemia (2)
- Ischemia/reperfusion injury (2)
- Ixodes ricinus (2)
- Jaw (2)
- Joint loading (2)
- KGF (2)
- Kardiovaskuläre Krankheit (2)
- Ketogenic diet (2)
- Ki-67 (2)
- Klebsiella pneumoniae (2)
- Knee joint (2)
- L-DOPA (2)
- L2 (2)
- LSCC (2)
- LVAD (2)
- Learning and memory (2)
- Left hemisphere (2)
- Leptin (2)
- Leukemia (2)
- Leukemias (2)
- Leukozyt (2)
- Linear regression analysis (2)
- Lipid signalling (2)
- Lipidomics (2)
- Liver (2)
- Liver cancer (2)
- Liver injury (2)
- Livestock (2)
- Local climate (2)
- Local therapy (2)
- Long-term potentiation (2)
- Longitudinal (2)
- Low back pain (2)
- Low-molecular-weight heparin (2)
- Low-virulent infection (2)
- Luciferase (2)
- Lucilia sericata (2)
- Lung cancer (2)
- Lyme borreliosis (2)
- Lymph nodes (2)
- Lymphectasia (2)
- Lymphocytes (2)
- Lymphoma (2)
- Lymphozyt (2)
- Lysophosphatidic acids (2)
- Lysosome (2)
- MALAT1 (2)
- MCAO (2)
- MCI (2)
- MICA (2)
- MLH1 (2)
- MLKL (2)
- MMP9 (2)
- MR spectroscopy (2)
- MTT assay (2)
- Macroautophagy (2)
- Magnetic resonance (2)
- Malaria prevalence (2)
- Marburg virus (2)
- Markovianity (2)
- Maxillary sinus (2)
- Medical consultation (2)
- Medical diagnostics (2)
- Medication Appropriateness Index (2)
- Medicine (2)
- Medizinstudenten (2)
- Meldepflicht (2)
- Membrane potential (2)
- Membrane proteins (2)
- Mesh (2)
- Meta-analysis (2)
- Metabolic syndrome (2)
- Metabolism (2)
- Metastasis (2)
- Metastatic (2)
- Metastatic breast cancer (2)
- Metastatic castration-resistant prostate cancer (2)
- Methicillin-resistant Staphylococcus aureus (2)
- Microglia (2)
- Microsurgery (2)
- Migrants (2)
- Minimal residual disease (2)
- Mitochondrial ROS (2)
- Mitochondrial complex I (2)
- MitraClip (2)
- Mixed methods (2)
- Mobilization (2)
- Model (2)
- Molecular autopsy (2)
- Molecular profiling (2)
- Molecular subtypes (2)
- Monitoring (2)
- Monocytes (2)
- Morphology (2)
- Morphometry (2)
- Mountain (2)
- Multidrug resistance (2)
- Multiple chronic conditions (2)
- Multivariable analysis (2)
- Mutation (2)
- Mutations (2)
- Myalgia (2)
- Myeloid Neoplasia (2)
- Myocardial perfusion (2)
- Myocarditis (2)
- NADH:ubiquinone oxidoreductase (2)
- NCCN (2)
- NCoR1 (2)
- NF-κB pathway (2)
- NFκB (2)
- NIRS (2)
- NK cells (2)
- NO (2)
- NOTCH1 (2)
- NS5A (2)
- Necrotizing enterocolitis (2)
- Neoplasms (2)
- Nepal (2)
- Nephrectomy (2)
- Nerve fibers (2)
- Nerve regeneration (2)
- Neural circuits (2)
- Neural stem cells (2)
- Neuroimaging (2)
- Neuron (2)
- Neuronal morphology (2)
- Neurons (2)
- Neurotoxicity (2)
- Nevirapine (2)
- Nicotine (2)
- Non-REM sleep (2)
- Non-interventional study (2)
- Normal distribution (2)
- Nox1 (2)
- Nucleic acid biomarkers (2)
- Nutrition (2)
- OCT (2)
- Observational (2)
- Obstetrics and gynecology (2)
- Occupational health (2)
- Olfactory system (2)
- Ophthalmology (2)
- Opioids (2)
- Opportunistic infections (2)
- Optical phenomena (2)
- Optogenetics (2)
- Oral immunotherapy (2)
- Oral surgery (2)
- Ordinary least squares (OLS) (2)
- Organ dysfunction (2)
- Organ dysfunctions (2)
- Organ preservation (2)
- Oroantral (2)
- Orthognathic surgery (2)
- Osteoarthritis (2)
- Osteogenic differentiation (2)
- Osteoporotic fractures (2)
- Outcome assessment (2)
- Outcomes research (2)
- Outpatients (2)
- Ovarian cancer (2)
- Oxidative stress (2)
- OxyELITE Pro (2)
- P2X7 receptor (2)
- P600 (2)
- PD-1 (2)
- PET (2)
- PINK1 (2)
- PML (2)
- PRNT (2)
- PROTAC (2)
- PSA (2)
- PTEN (2)
- Pacemaker (2)
- Pain management (2)
- Palliative care (2)
- Palliative care [MeSH] (2)
- Parenteral nutrition (2)
- Parkin (2)
- Parkinson disease (2)
- Particulate matter (2)
- Pathologic complete response (2)
- Pathology (2)
- Patient manikins (2)
- Patient needs (2)
- Patient preference (2)
- Patientenbedürfnisse (2)
- Patterns of care (2)
- Pediatric infections (2)
- Pelargonium sidoides (2)
- Penile cancer (2)
- Percutaneous coronary intervention (2)
- Periodontal treatment (2)
- Periodontitis (2)
- Peritonitis (2)
- Persistence (2)
- Person-Umwelt-Passung (2)
- Person-environment fit (2)
- Petri net (2)
- Philadelphia chromosome (2)
- Phylogenetic analysis (2)
- Physical environment (2)
- Plasma (2)
- Plasmodium (2)
- Plasticity (2)
- Plerixafor (2)
- Plk1 inhibitors (2)
- Pneumocystis jirovecii (2)
- Point-of-care testing (2)
- Polytrauma (2)
- Positron emission tomography (2)
- Post-mortem interval (2)
- Post-translational modifications (2)
- Postoperative radiochemotherapy (2)
- Posttraumatic stress disorder (2)
- Posture analysis (2)
- Poverty (2)
- Practical skills (2)
- Predictive coding (2)
- Predominant polarity (2)
- Preeclampsia (2)
- Preventive medicine (2)
- Primary cilium (2)
- Prisoners (2)
- Prisons (2)
- Probability density (2)
- Probability distribution (2)
- Prognostic (2)
- Prognostic tool (2)
- Prostatic neoplasms (2)
- Proteasome (2)
- Protein Translocation (2)
- Protein biomarkers (2)
- Protein translation (2)
- Protein-Protein Interactions (2)
- Pseudomonas aeruginosa (2)
- Psychedelics (2)
- Pulmonary veins (2)
- Qualitative research (2)
- Quality of care (2)
- Questionnaires (2)
- RDoC (2)
- RIPK3 (2)
- RMS (2)
- RNA binding proteins (2)
- RNA interference (2)
- RNA interference (RNAi) (2)
- RNA isolation (2)
- RNA therapy (2)
- RNA-sequencing (2)
- RNAseq (2)
- RNF4 (2)
- ROS1 (2)
- Rab7 (2)
- Radiation (2)
- Radical prostatectomy (2)
- Radiochemotherapy (2)
- Rainfall (2)
- Random forest (2)
- Randomized controlled trials (2)
- Recurrence (2)
- Red blood cell transfusion (2)
- Redoxin (2)
- Refractory ALL (2)
- Regeneration (2)
- Relaxometry (2)
- Reliability (2)
- Remission (2)
- Renal system (2)
- Reproducibility (2)
- Rescue medication (2)
- Research architecture (2)
- Respiratory chain (2)
- Respiratory distress syndrome (2)
- Respiratory infections (2)
- Restenosis (2)
- Resting-state (2)
- Reward (2)
- Rheumatoid Arthritis (2)
- Ribavirin (2)
- Risiko (2)
- Risk assessment (2)
- Risk factor (2)
- Risk stratification (2)
- Rivaroxaban (2)
- Roussel Uclaf Causality Assessment Method (RUCAM) (2)
- Rural area (2)
- S1P lyase (2)
- S1P receptors (2)
- SAMHD1 (2)
- SARS coronavirus (2)
- SARS-CoV-2 monitoring (2)
- SARS-CoV-2 testing (2)
- SARS‐CoV‐2 (2)
- SCC (2)
- SCCHN (2)
- SD-OCT (2)
- SENP (2)
- SF-36 (2)
- SIRT1 (2)
- SKAP1 (2)
- SOD (2)
- SPM (2)
- SPTAN1 (2)
- STAT1 (2)
- STING (2)
- SV2A (2)
- SVR (2)
- Scheimpflug imaging (2)
- Scientists (2)
- Self-renewal (2)
- Sensory processing (2)
- Serum (2)
- Sestrin 2 (2)
- Short bowel syndrome (2)
- Simulation training (2)
- Skills (2)
- Smoking habits (2)
- Social epidemiology (2)
- Social health determinants (2)
- Social participation (2)
- Socio-economic analysis (2)
- Socioeconomic status (2)
- Sonication (2)
- Sorafenib (2)
- Specificity (2)
- Speech (2)
- Sphingolipids (2)
- Spinal cord (2)
- Spirochetes (2)
- Standard endoscopy (2)
- Standard value (2)
- Standardization (2)
- Stem-cell therapies (2)
- Strength training (2)
- Streptococcus pneumoniae (2)
- Stress (2)
- Striatum (2)
- Structural plasticity (2)
- Study protocol (2)
- Subarachnoid hemorrhage (2)
- Sudden death (2)
- Sumatra (2)
- Sunitinib (2)
- Superficial vein thrombosis (2)
- Superoxide (2)
- Supported decision making (2)
- Survival analysis (2)
- Survivin (2)
- Sweden (2)
- Synaptic plasticity (2)
- Synaptic transmission (2)
- Synovial sarcoma (2)
- Systematic reviews (2)
- Systemic inflammation (2)
- Systemic therapy (2)
- T-cell (2)
- T-cell receptor (2)
- T-cells (2)
- TACE (2)
- TBK1 (2)
- TBSS (2)
- TF-complexes (2)
- TGF-β1 (2)
- TGFβ (2)
- TMT (2)
- TRPA1 (2)
- TSC (2)
- Target identification (2)
- Targeted therapies (2)
- Teaching (2)
- Teeth (2)
- Tenofovir (2)
- Thailand (2)
- Theft (2)
- Thermoregulation (2)
- Thromboembolism (2)
- Thrombolysis (2)
- Thrombotic thrombocytopenic purpura (2)
- Thyroid (2)
- Tick (2)
- Tight junctions (2)
- Toll-like receptor (2)
- Tomography (2)
- Tomography (x-ray computed) (2)
- Tooth loss (2)
- Transcription (2)
- Transcription Factors (2)
- Transmission (2)
- Traumatic brain injury (2)
- Traumatic injury (2)
- Treg cell (2)
- Troponin (2)
- Tumour immunology (2)
- UGCG (2)
- Ubiquitin Ligase (2)
- Ubiquitylation (2)
- Ulcerative colitis (2)
- Ultrasonography (2)
- Unterstützung der Umwelt (2)
- Urethral cancer (2)
- Urology (2)
- Usability (2)
- Uteroglobin (2)
- V4 (2)
- VDR (2)
- VEGF receptors (2)
- VIGALL (2)
- VRE (2)
- Vaccine (2)
- Vaccine uptake rate (2)
- Validity (2)
- Vascular endothelial growth factor (VEGF) (2)
- Vascularization (2)
- Vasculitis (2)
- Veins (2)
- Viral infection (2)
- Vision (2)
- Visual acuity (2)
- Visual estimation (2)
- Visual quality (2)
- Vitamin D (2)
- Vitamin D deficiency (2)
- Vmem (2)
- Volume therapy (2)
- Warburg effect (2)
- Wearable cardioverter-defibrillator (2)
- White blood cells (2)
- Wnt (2)
- Women (2)
- Working memory (2)
- Wounds (2)
- X-ray crystallography (2)
- Zebrafish (2)
- Zika fever (2)
- Zoopotentation (2)
- Zooprophylaxis (2)
- ablation (2)
- abuse (2)
- accident (2)
- acetyl-CoA (2)
- acute lung injury (2)
- acute myeloid leukaemia (2)
- acute respiratory distress syndrome (2)
- adalimumab (2)
- additives (2)
- adenovirus (2)
- adherence (2)
- adipocytes (2)
- adipose-derived mesenchymal stem cells (2)
- adipose-derived stromal/stem cells (2)
- adjuvant therapy (2)
- adjuvante Therapie (2)
- adolescence (2)
- adoptive cancer immunotherapy (2)
- adult (2)
- adult neurogenesis (2)
- advanced care planning (2)
- adverse reaction (2)
- age-related macular degeneration (2)
- air flow (2)
- alcoholic liver disease (2)
- algorithm (2)
- allogeneic hematopoietic stem cell transplantation (2)
- alpha band (2)
- alpha power (2)
- alpha-synuclein (2)
- amino acids (2)
- amphiregulin (2)
- amyotrophic lateral sclerosis (ALS) (2)
- analgesics (2)
- anaplastic large cell lymphoma (2)
- angiography (2)
- animal experiment (2)
- animal experiments (2)
- anorexia nervosa (2)
- antibacterial activity (2)
- antibiotic resistance (2)
- antibiotic therapy (2)
- anticoagulation (2)
- anticonvulsants (2)
- antiepileptic drug (2)
- antiepileptic drugs (2)
- antifungal therapy (2)
- antioxidant (2)
- antiseizure medication (2)
- antisocial behavior (2)
- antiviral drugs (2)
- anxiety (2)
- aortic valve stenosis (2)
- aptamer (2)
- arachidonic acid (2)
- arousal (2)
- arthritis (2)
- aspirin (2)
- astrocytoma (2)
- atezolizumab (2)
- attachment loss (2)
- audiovisual (2)
- auditory cortex (2)
- autism (2)
- autoantibodies (2)
- autoimmune diabetes (2)
- autoimmune disease (2)
- autoimmunity (2)
- autologous stem cell transplantation (2)
- automation (2)
- betulinic acid (2)
- bibliometric analysis (2)
- biliary stricture (2)
- bio imaging (2)
- biocompatibility (2)
- biofilm (2)
- biologics (2)
- bioluminescence (2)
- biopsy (2)
- biopsy cores (2)
- blood flow restriction (2)
- blood pressure (2)
- blood-brain barrier (2)
- body plethysmography (2)
- bone healing (2)
- bone marrow microenvironment (2)
- bone metabolism (2)
- bone metastasis (2)
- borrelia (2)
- brain cancer (2)
- brain function (2)
- brain networks (2)
- brain states (2)
- brain tumor (2)
- brain-derived neurotrophic factor (2)
- brainstem (2)
- bulimia nervosa (2)
- cART (2)
- cabozantinib (2)
- calcitriol (2)
- callous-unemotional traits (2)
- calprotectin (2)
- campesterol (2)
- cancer cell metabolism (2)
- cancer therapy (2)
- cancer treatment (2)
- cancer-associated fibroblasts (2)
- cancer-specific mortality (2)
- cancer-specific survival (2)
- cannabis (2)
- capsaicin (2)
- carbapenem resistance (2)
- carbapenemase (2)
- cardiolipin (2)
- cardiovascular (2)
- case-referent study (2)
- caspase-1 (2)
- cataract surgery (2)
- cell motility (2)
- cell proliferation (2)
- cells (2)
- central nervous system (2)
- ceramide (2)
- cerebral hemorrhage (2)
- cerebral venous thrombosis (2)
- cerebrovascular disease (2)
- cesarean section (2)
- chemotaxis (2)
- chemotherapy resistance (2)
- chest trauma (2)
- childhood acute myeloid leukemia (2)
- childhood cancer (2)
- children and adolescents (2)
- cholangiocarcinoma (2)
- cholestanol (2)
- cholesterol absorption (2)
- cholesterol synthesis (2)
- chronic granulomatous disease (2)
- chronic hepatitis C (2)
- chronic inflammation (2)
- chronic thromboembolic pulmonary hypertension (2)
- cigarette (2)
- circadian (2)
- circadian rhythm (2)
- circadian rhythms (2)
- circular RNA (2)
- cisplatin resistance (2)
- citation (2)
- cleaning (2)
- clinical benefit (2)
- clinical immunology (2)
- clinical isolates (2)
- clinical studies (2)
- clinically important restrictions and symptoms (2)
- coagulopathy (2)
- cochlea (2)
- colon (2)
- colon carcinoma cells (2)
- colorectal cancer (CRC) (2)
- colorectal carcinoma (2)
- comorbidities (2)
- complementary and alternative medicine (2)
- complementary medicine (2)
- complex I (2)
- complex systems (2)
- compliance (2)
- complication (2)
- computational neuroscience (2)
- computer-assisted (2)
- concordance (2)
- congenital diaphragmatic hernia (2)
- connective tissue (2)
- consensus (2)
- constipation (2)
- contemporary (2)
- continuous performance test (2)
- convulsive seizures (2)
- coping (2)
- corneal edema (2)
- corneal transplantation (2)
- corona virus (2)
- coronary artery bypass graft surgery (2)
- coronary artery disease (2)
- corpus callosum (2)
- cost-effective (2)
- critical size defect (2)
- criticality (2)
- critically ill patients (2)
- cryoballoon (2)
- cryopreservation (2)
- cyclooxygenase (2)
- cyclosporin A (2)
- cytochrome P450 2E1 (2)
- cytokine (2)
- cytotoxic T cells (2)
- dabrafenib (2)
- dance (2)
- deafness (2)
- decision making (2)
- decompensated liver cirrhosis (2)
- delay (2)
- delirium (2)
- dental assistant (2)
- dental assistants (2)
- dentists (2)
- dentoalveolar surgery (2)
- desensitization (2)
- detoxification (2)
- deubiquitinase (DUB) (2)
- diagnostics (2)
- diet (2)
- dietary supplements (2)
- dihydroceramide (2)
- disease burden (2)
- disease models (2)
- disease progression (2)
- disintegration (2)
- dislocation (2)
- distress (2)
- docetaxel (2)
- doxycycline (2)
- drug release (2)
- drug-induced liver injury (2)
- dual task (2)
- dysphagia (2)
- early breast cancer (2)
- eating disorders (2)
- economic burden (2)
- education (2)
- eicosanoids (2)
- elderly patients (2)
- electrocardiography (2)
- electron transport chain (2)
- emergency care (2)
- encoding (2)
- endoscopic retrograde cholangiopancreatography (2)
- endothelial (2)
- endothelial cell (2)
- endovascular treatment (2)
- entorhinal cortex lesion (2)
- ephrinB2 (2)
- epidemics (2)
- epidermal growth factor (2)
- epigenetic (2)
- epileptic encephalopathy (2)
- epileptogenesis (2)
- epithelial to mesenchymal transition (2)
- erastin (2)
- erectile dysfunction (2)
- esophageal cancer (2)
- euthymic (2)
- evaluation (2)
- evolution (2)
- expertise (2)
- extraversion (2)
- factor H (2)
- faculty development (2)
- fall (2)
- fasting (2)
- feedback (2)
- female subjects (2)
- femoral artery ligation (2)
- ferric carboxymaltose (2)
- ferroptosis (2)
- fibrinolysis (2)
- focal therapy (2)
- fracture (2)
- frühes Mammakarzinom (2)
- functional genetics (2)
- functional genomics (2)
- furcation involvement class III (2)
- fusion (2)
- fusion biopsy (2)
- gait analysis (2)
- gene signature (2)
- genetic diversity (2)
- genetics (2)
- genome (2)
- glecaprevir (2)
- glucose metabolism (2)
- growth factor (2)
- guided bone regeneration (2)
- guidelines (2)
- haemophilia (2)
- haemophilia A (2)
- head and neck neoplasms (2)
- head and neck squamous cell carcinoma (2)
- health (2)
- health care (2)
- health information exchange (2)
- healthcare personnel (2)
- healthcare workers (2)
- hearing loss (2)
- hedgehog signaling (2)
- hematopoiesis (2)
- hematopoietic stem cells (2)
- hemolysis (2)
- hemorrhagic transformation (2)
- hepatic encephalopathy (2)
- hepatitis B virus (2)
- hepatotoxicity (2)
- herbal hepatotoxicity (2)
- hippocampal sclerosis (2)
- histamine (2)
- histological validation (2)
- histone deacetylase (2)
- histone deacetylase inhibitor (2)
- homeostatic plasticity (2)
- human biology and medicine (2)
- human cytomegalovirus (2)
- human genomics (2)
- human immunodeficiency virus (2)
- humans (2)
- hyperalgesia (2)
- hyperhomocysteinemia (2)
- iCBT (2)
- iDILI (2)
- iPS (2)
- idiopathic pulmonary fibrosis (2)
- immune system (2)
- immune therapy (2)
- immunocytochemistry (2)
- immunosuppression (2)
- induced membrane (2)
- induction chemotherapy (2)
- infections (2)
- infectious disease (2)
- infectivity (2)
- infiltration (2)
- inhibitors (2)
- injury (2)
- inner ear (2)
- insulin (2)
- integrated stress response (2)
- integration (2)
- integrative medicine (2)
- interferon (2)
- interferon gamma (2)
- interleukin-18 (2)
- interleukin-4 (2)
- interleukins (2)
- intermediate risk (2)
- internet (2)
- intracranial hemorrhage (2)
- irritable bowel syndrome (2)
- job-exposure matrix (2)
- joint contact forces (2)
- keratinized mucosa (2)
- kidney cancer (2)
- kidney function (2)
- kinase inhibitor (2)
- kinase regulation (2)
- kinematic analysis (2)
- kinematics (2)
- knowledge discovery (2)
- lapatinib (2)
- lathosterol (2)
- layer-specificity (2)
- lenalidomide (2)
- leukodystrophy (2)
- leukopenia (2)
- leukotriene (2)
- lifestyle intervention (2)
- lipidomics (2)
- liver damage (2)
- liver disease (2)
- liver metastases (2)
- local control (2)
- local information dynamics (2)
- local recurrence (2)
- localized prostate cancer (2)
- long-term outcome (2)
- long-term potentiation (2)
- long-term success (2)
- long-term survival (2)
- long-term tooth survival (2)
- longevity (2)
- low molecular weight heparin (2)
- low-glycaemic meal replacement (2)
- lung development (2)
- lymph node dissection (2)
- lymphocytes (2)
- mRNA stability (2)
- mTOR inhibitor (2)
- maintenance (2)
- malignancy (2)
- mammary carcinoma (2)
- mandatory reporting (2)
- marginal bone loss (2)
- mast cells (2)
- mathematical models of viral RNA cycle (2)
- matrix (2)
- medical education (2)
- medication management (2)
- medication review (2)
- medulloblastoma (2)
- melatonin (2)
- membrane protein complex (2)
- mental health (2)
- mesenchymal stromal cell (2)
- meta-analysis (2)
- metastatic (2)
- metastatic castration-resistant prostate cancer (2)
- methylprednisolone (2)
- miR (2)
- miR-181 (2)
- miR-21 (2)
- microdosing (2)
- microenvironment (2)
- microsurgery (2)
- modularity (2)
- molecular dynamics (2)
- molecular marker (2)
- molecular mimicry (2)
- molecular typing (2)
- monoclonal antibody (2)
- morbidity (2)
- morphogenesis (2)
- morphometry (2)
- mouse models (2)
- mucormycetes (2)
- multicentre study (2)
- multidetector computed tomography (2)
- multinucleated giant cells (2)
- multisensory integration (2)
- musculoskeletal (2)
- musculoskeletal modeling (2)
- music (2)
- myelodysplastic syndrome (2)
- nanoparticles (2)
- natural product (2)
- ncRNA (2)
- neoadjuvant chemotherapy (2)
- network analysis (2)
- neural network (2)
- neurocognition (2)
- neurocognitive (2)
- neurodegenerative diseases (2)
- neuroendocrine (2)
- neurogenesis (2)
- neuromodulation (2)
- neurooncology (2)
- neuropathy (2)
- neurophysiology (2)
- neuroprotection (2)
- neuroticism (2)
- neutropenia (2)
- neutrophils (2)
- newborn (2)
- next generation sequencing (2)
- next generation sequencing (NGS) (2)
- niche (2)
- nivolumab (2)
- non-small cell lung cancer (2)
- non-small-cell lung cancer (2)
- nursery schools (2)
- nutlin-3 (2)
- occupational exposure (2)
- occupational health (2)
- occupational infections (2)
- olfaction (2)
- oligomerisation (2)
- omega-3 fatty acids (2)
- oncogene (2)
- oncomodulation (2)
- online survey (2)
- oral and maxillofacial surgery (2)
- oscillations (2)
- osteogenesis (2)
- other-cause mortality (2)
- out-patient paediatrics (2)
- p16 (2)
- paclitaxel (2)
- pain management (2)
- paired associative stimulation (2)
- palatal tremor (2)
- partial information decomposition (2)
- passive smoke (2)
- pathology (2)
- patient (2)
- patient centered care (2)
- patient preferences (2)
- patient triage (2)
- patient-reported outcomes (2)
- pediatric surgery (2)
- pelvic packing (2)
- penile cancer (2)
- peptide aptamer (PA) (2)
- peri-implant diseases (2)
- pericytes (2)
- periodontal diseases (2)
- periodontitis stage III and IV (2)
- peri‐implantitis (2)
- pertussis (2)
- phagocytes (2)
- pharmacogenetics (2)
- pharmacokinetics (2)
- pharmacoresistance (2)
- pharmacovigilance (2)
- phosphate (2)
- photodynamic therapy (2)
- physiotherapy (2)
- pibrentasvir (2)
- platelet-rich fibrin (2)
- polo-like kinase 1 (2)
- poly(lactic-co-glycolic acid) (PLGA) (2)
- polygenic risk score (2)
- polymerase chain reaction (2)
- polymorphism (2)
- population dynamics (2)
- post-translational modifications (2)
- postoperative complications (2)
- postoperative pain (2)
- posttraumatic stress disorder (2)
- preclinical (2)
- prediction (2)
- predictive (2)
- predictor (2)
- preterm birth (2)
- primary sclerosing cholangitis (2)
- process evaluation (2)
- prognostic (2)
- prognostic factors (2)
- prognostic value (2)
- progranulin (2)
- prostaglandin E (2)
- prostate carcinoma cells (2)
- proteasome (2)
- proteasome inhibitor (2)
- protein kinase (2)
- protein phosphorylation (2)
- protein quality control (2)
- protein-protein interaction (2)
- protein-rich (2)
- proteostasis (2)
- proximal tubule (2)
- psychiatric disorders (2)
- psychiatry (2)
- psychosis (2)
- pulmonary embolism (2)
- pulmonary vein isolation (2)
- pulse wave velocity (2)
- qRT-PCR (2)
- quality (2)
- quality assurance (2)
- quantum biology (2)
- radical cystectomy (2)
- radioimmunotherapy (2)
- randomized (2)
- randomized controlled trial (2)
- rare disease (2)
- rare diseases (2)
- rat model (2)
- re-osseointegration (2)
- real-world (2)
- real-world data (2)
- recommendations (2)
- reference values (2)
- refractory (2)
- regenerative medicine (2)
- regulatory T cell (2)
- relapse (2)
- relaxometry (2)
- reliability (2)
- renal failure (2)
- renal tubular epithelial cells (2)
- research (2)
- residual myometrial thickness (2)
- resistance mutation (2)
- resistant cell lines (2)
- resolution (2)
- resolution of inflammation (2)
- respiratory chain (2)
- respiratory failure (2)
- respiratory tract infection (2)
- resting-state (2)
- resveratrol (2)
- revision surgery (2)
- ribavirin (2)
- risk (2)
- risk assessment (2)
- risk group (2)
- risk prediction (2)
- saliva (2)
- salvage radical prostatectomy (2)
- sarcoma (2)
- scaffold (2)
- school-based prevention (2)
- scientometrics (2)
- scientometry (2)
- second-hand smoke (2)
- second-line (2)
- secondary data analysis (2)
- secretion (2)
- secretome (2)
- secukinumab (2)
- selection (2)
- sensory neuropathy (2)
- serine protease (NS3-4A) (2)
- shunt (2)
- siRNA (2)
- signal transducer and activator of transcription 5 (Stat5) (2)
- signature (2)
- simulation (2)
- single-sided deafness (2)
- sitosterol (2)
- skin (2)
- smoking cessation (2)
- smooth muscle cells (2)
- soft tissue (2)
- soluble MICA (2)
- sound-induced flash illusion (2)
- speech perception (2)
- sphingosine 1-phosphate receptor (2)
- sphingosine kinase (2)
- spiking neural networks (2)
- spinal dural leaks (2)
- spine head (2)
- sport (2)
- spreadsheet (2)
- squamous cell carcinoma (2)
- stability (2)
- stage (2)
- stakeholder analysis (2)
- standard value (2)
- starvation (2)
- stationarity (2)
- steatosis (2)
- stem cells (2)
- stereotactic radiosurgery (2)
- stress granules (2)
- study protocol (2)
- sub-lineage (2)
- subchondral bone (2)
- superficial siderosis (2)
- survival rate (2)
- survivin (2)
- sympathetic nervous system (2)
- symptoms (2)
- synaptopodin (2)
- synchronization (2)
- synchrony (2)
- synergy (2)
- synovium (2)
- tDCS (2)
- telemedicine (2)
- temperature (2)
- temsirolimus (2)
- testosterone (2)
- tetracycline (2)
- tetrahydrobiopterin (2)
- tetrahydrocannabinol (2)
- therapy monitoring (2)
- therapy resistance (2)
- tissue Doppler imaging (2)
- tobacco (2)
- tobacco smoke (2)
- tolerability (2)
- tolerance (2)
- tooth transplantation (2)
- total hip replacement (2)
- tracking (2)
- trafficking (2)
- training (2)
- transcription factors (2)
- transcriptomics (2)
- transforming growth factor-β (2)
- translation (2)
- trastuzumab (2)
- trials (2)
- triple-negative breast cancer (2)
- trophoblast (2)
- trophoblasts (2)
- tuberous sclerosis complex (2)
- tumor (2)
- tumor angiogenesis (2)
- tumor infiltrating lymphocytes (2)
- tumor necrosis factor (2)
- tumor stroma (2)
- tumor suppressor (2)
- tumor-infiltrating lymphocytes (2)
- type 1 diabetes (2)
- unilateral hip osteoarthritis (2)
- upgrading (2)
- urethral stricture (2)
- urethroplasty (2)
- urinary incontinence (2)
- urological cancer (2)
- ursodeoxycholic acid (2)
- ustekinumab (2)
- uteroglobin (2)
- vaccination rates (2)
- vascular biology (2)
- vascular disease (2)
- vasodilation (2)
- ventral striatum (2)
- very high risk (2)
- virus (2)
- viruses (2)
- visual cortex (2)
- vitamin B deficiency (2)
- von Willebrand disease (2)
- von Willebrand factor (2)
- waiting time (2)
- walking (2)
- weight loss (2)
- weight reduction (2)
- white matter hyperintensity (2)
- within-host viral modelling (2)
- women (2)
- workflow (2)
- zebrafish (2)
- zinc (2)
- Ärztliche Aufklärung (2)
- (cardiac) surgery (1)
- (lyso)phospholipids (1)
- (novel) brominated flame retardants ((N)BFR) (1)
- (sub-) luxation (1)
- 1,2-dichloroethane (1)
- 1,25-Dihydroxyvitamin D (1)
- 1-propanol (1)
- 14-3-3 gene family (1)
- 15-PGDH (1)
- 16 segment AHA model (1)
- 16S rRNA sequencing (1)
- 16p11.2 (1)
- 17-AAG (1)
- 17‐OH itraconazole (1)
- 19F MR spectroscopy (1)
- 1H MR spectroscopy (1)
- 1H NMR; Conformational Properties (1)
- 1α,25(OH)2D3 (1)
- 2-AG (1)
- 2-Arachidonoyl glycerol (1)
- 2-deoxy-d-glucose (1)
- 2-deoxyglucose (2-DG) (1)
- 2-hydroxyglutarate (1)
- 2019-nCoV (1)
- 223Radium-dichloride (1)
- 26 LncRNA (1)
- 2‑methoxyestradiol (1)
- 2′,3′-cGAMP (1)
- 3 mm RAS instruments (1)
- 3 mm instruments (1)
- 3-hydroxyanthranilic acid (1)
- 3-hydroxyisovaleryl carnitine (1)
- 3-year survival (1)
- 32D progenitor cells (1)
- 3Cs technology (1)
- 3D culture (1)
- 3D gait analysis (1)
- 3D laparoscopy (1)
- 3D printed cell-free scaffold (1)
- 3D printing using composite resin (1)
- 3D printing using zirconia (1)
- 3D spatiotemporal resolved mathematical models (1)
- 3D tissue models (1)
- 3D-models (1)
- 3D-printing (1)
- 3T3-L1 mouse fibroblasts (1)
- 3years (1)
- 4-1BB (1)
- 4-FA (1)
- 4-fluoroamphetamine (1)
- 5 lipoxygenase (1)
- 5' UTR (1)
- 6-Schritt-Methode (1)
- 8 weeks (1)
- 9-aminoacridine (1)
- 90% or more improvement in baseline Psoriasis Area and Severity Index (1)
- 99mTc-MIBI (1)
- 99mTc-pertechnetate (1)
- A-FFIP (1)
- A-PRF+ (1)
- A2BP1 (1)
- A375 human melanoma cell line (1)
- A375 human melanoma cells (1)
- A498 cells (1)
- A549 (1)
- AA-amylodosis (1)
- AAA (1)
- AAA+ disaggregase (1)
- AB-serum (1)
- ABC transporter (1)
- ABCB5 (1)
- ABS (1)
- ABT-737 (1)
- ACE inhibitor (1)
- ACE-inhibitor (1)
- ACKR (1)
- ACT-777991 (1)
- ACTH (1)
- ACURATE neo (1)
- ADAM-17 (1)
- ADAM10 (1)
- ADAMTS-13 (1)
- ADAMTS13 (1)
- ADCC (1)
- ADGRE1 (1)
- ADHD differential diagnosis (1)
- ADHS (1)
- AGC kinase (1)
- AGMO (1)
- AICAR (1)
- AIH immunopathogenesis (1)
- AIS (1)
- AJAP1 (1)
- AKT (1)
- AKT signaling (1)
- AKT-mTOR pathway (1)
- ALD (1)
- ALDH2 (1)
- ALF (1)
- ALK gene (1)
- ALK-rearranged NSCLC (1)
- AMD3100 (1)
- AML – acute myeloid leukemia (1)
- AMP-activated kinase (1)
- AMP-activated kinase (AMPK) (1)
- AO-PCCF (1)
- AOSpine (1)
- AOSpine injury score (1)
- APMPPE - acute posterior multifocal placoid pigment epitheliopathy (1)
- APP (1)
- APP processing (1)
- APRI (1)
- APT-CEST (1)
- ARA (1)
- ARID5B (1)
- ASA404 (1)
- ASAP (1)
- ASCT (1)
- ASD-specific (1)
- ASO (1)
- ASPECTS (1)
- AT-101 (1)
- AT1 receptor antagonist (1)
- ATG3 (1)
- ATG4 (1)
- ATG8 (1)
- ATO (1)
- ATXN2 (1)
- AU-rich element (1)
- AVM hemorrhage (1)
- AZD7762 (1)
- Abatacept (1)
- Abdominal infections (1)
- Abdominal surgery (1)
- Abdominal trauma (1)
- Abductor pollicis longus (1)
- Abiraterone acetate (1)
- Abl kinase inhibitors (1)
- Ablation (1)
- Ablation Techniques (1)
- Abrasion (1)
- Abronia graminea (1)
- Abronia lythrochila (1)
- Absenteeism (1)
- Absolute quantification (1)
- Abusive head trauma (AHT) (1)
- Academic health centres (1)
- Academics (1)
- Accelerometry (1)
- Accessibility (1)
- Accidents (1)
- Accumulated degree days (1)
- Acellular dermis (1)
- Acer platanoides (1)
- Acid ceramiase (1)
- Acidic Amino Acids (1)
- Acquired drug resistance (1)
- Acquired resistance (1)
- Actaea cimicifuga (1)
- Actin (1)
- Actinomycin D (1)
- Action potential (1)
- Activated partial thromboplastin time (1)
- Active middle ear implants (1)
- Activity control (1)
- Acute (1)
- Acute HIV infection (1)
- Acute Hemiparesis (1)
- Acute Myeloid Leukemia (1)
- Acute appendicitis (1)
- Acute bronchitis (1)
- Acute calcolous cholecystitis (1)
- Acute coronary syndrome (1)
- Acute cough (1)
- Acute elbow dislocation (1)
- Acute heart failure (1)
- Acute hospital (1)
- Acute kidney failure (1)
- Acute leukemia (1)
- Acute respiratory distress syndrom (1)
- Acute-on-chronic subdural hematoma (1)
- Adeno associated virus (1)
- Adenylyl cyclase (1)
- Adherence junctions (1)
- Adhesins (1)
- Adipose tissue-derived mesenchymal stem cells (1)
- Adiposity (1)
- Adjustment of dosage at steady state (1)
- Adjuvant therapies (1)
- Administrative claims data (1)
- Adolescence (1)
- Adult (1)
- Adult T-cell acute lymphoblastic leukemia (1)
- Adult-onset ADHD (1)
- Advanced biliary tract cancer (1)
- Advanced breast cancer (1)
- Advanced glycation endproducts (1)
- Advanced stage (1)
- Adverse effects (1)
- Aeroplysinin-1 (1)
- Affect (1)
- Affective Misattribution Procedure (1)
- Affective disorders (1)
- Affinity Chromatography (1)
- Affinity Labeling (1)
- Africa (1)
- Ag-RDT (1)
- Aganglionosis (1)
- Age (1)
- Age determination (1)
- Age determination by skeleton (1)
- Ageing (1)
- Aggression (1)
- Aggressive periodontitis (1)
- Agoraphobia (1)
- Agreement (1)
- Air traffic (1)
- Airport-related emissions (1)
- Airways (1)
- Akt-mTOR pathway (1)
- Akt-mTOR signaling (1)
- Aktivierte partielle Thromboplastinzeit (1)
- Akute lymphatische Leukämie (1)
- Akutes Koronarsyndrom (1)
- Albumin (1)
- Albumin ratio (1)
- Aliphatic halogenated hydrocarbons (1)
- Alisertib (1)
- All oral (1)
- All-oral therapy (1)
- All-trans retinoic acid (1)
- Allergen immunotherapy (1)
- Allergic rhinitis (1)
- Allergoid (1)
- Allgemeinmedizin (1)
- Allochromatium vinosum (1)
- Allogeneic (1)
- Allogeneic Stem Cell Transplantation (SCT) (1)
- Allogeneic hematopoietic stem (1)
- Allogeneic stem cell transplantation (1)
- Allograft bone block (1)
- Alpelisib (1)
- Alpha oscillations (1)
- Alpha power (1)
- Alpha-fetoprotein (AFP) (1)
- Alpha-synuclein (1)
- Alpha-synuclein deficiency (1)
- Alternative oxidase (1)
- Alveolar ridge augmentation (1)
- Alzheimer’s dementia (1)
- Ambient air (1)
- Ambroxol (1)
- Ambulatory Assessment (1)
- Ameloblastoma (1)
- Amino acid analysis (1)
- Amino acids (1)
- Aminosäuremetabolismus (1)
- Aminosäuren (1)
- Aminotransferases (1)
- Amisulpride (1)
- Amitriptyline (1)
- Amizon (1)
- Amniotic fluid (1)
- Amphetamine (1)
- Amygdala (1)
- Amyloid precursor protein (1)
- Amyloid-beta 42 (1)
- Amyotrophic lateral sclerosis (1)
- Anaesthesia (1)
- Anahuasca (1)
- Anakinra (1)
- Analgesie (1)
- Analogue modelling (1)
- Analysis tool (1)
- Anaplastic astrocytoma (1)
- Anatomic competence (1)
- Andersen-Tawil syndrome (1)
- Anderson–Fabry (1)
- Andexanet alpha (1)
- Andropogon virginicus (1)
- Anemia management (1)
- Anesthesia, Intravenous (1)
- Aneurysm (1)
- Aneurysmal subarachnoid hemorrhage (1)
- Aneurysms (1)
- Angiectasia (1)
- Angiodysplasia (1)
- Angioedema (1)
- Angiogenèse (1)
- Angiomyolipoma (1)
- Angioplasty (1)
- Angststörungen (1)
- Animal disease models (1)
- Animal experiment (1)
- Animal wings (1)
- Anion and Zwitterion Transport (1)
- Aniridia (1)
- Ankle arthrometer (1)
- Anomalous venous atrial connections (1)
- Anopheles (1)
- Anorexia Nervosa (1)
- Anosmia (1)
- Anschlussheilbehandlung (1)
- Antagonist (1)
- Antarctic marine sponges (1)
- Anterior cingulate cortex (1)
- Anterior cruciate ligament (1)
- Anterior cruciate ligament reconstruction (1)
- Anti platelet therapy (1)
- Anti-CMV IgG (1)
- Anti-TNF (1)
- Anti-inflammatory (1)
- Anti-rheumatic agents (1)
- Anti-seizure medication (1)
- Anti-tumor immunity (1)
- Antiangiogenesis (1)
- Antibiotic (1)
- Antibiotic generic drugs (1)
- Antibiotic steward-ship (1)
- Antibiotic stewardship (1)
- Antibiotic therapy (1)
- Antibody avidity (1)
- Antibody isotypes (1)
- Antibody therapy (1)
- Antibody-mediated rejection (1)
- Anticholinergic (1)
- Anticoagulant (1)
- Anticoagulants (1)
- Anticoagulants [MeSH] (1)
- Anticonvulsant (1)
- Anticonvulsants (1)
- Antidepressant (1)
- Antifungal agents (1)
- Antigen test (1)
- Antigen-presenting cells (1)
- Antigennachweis (1)
- Antigens (1)
- Antihormone therapy (1)
- Antimicrobial resistance (1)
- Antineoplastic agents (1)
- Antioxidant (1)
- Antioxidants (1)
- Antiplatelet therapy (1)
- Antiproliferative (1)
- Antireflux surgery (1)
- Antirheumatic agents (1)
- Antithrombotic therapy (1)
- Antivenom (1)
- Antiviral agents (1)
- Antiviral immune response (1)
- Antiviral response (1)
- Anura (1)
- Anwendbarkeit (1)
- Anxiolytic pharmacological therapy (1)
- Aortic Valve Replacement (1)
- Aortic aneurysm (1)
- Aortic arch replacement (1)
- Aortic debranching (1)
- Aortic input function (1)
- Aortic stiffness (1)
- Aortic valve sparing (1)
- Aperiodic (1)
- Apes (1)
- Aphakia (1)
- Aphantasia (1)
- Apoptotic cell death (1)
- Appendectomy (1)
- Aquaporins (1)
- Ara h2-specific IgE (1)
- Arabin pessary (1)
- Arabin-Pessar (1)
- Arbeitsgedächtnis (1)
- ArchT (1)
- Archaebacterial Lipids (1)
- Area deprivation (1)
- Arms (1)
- Aromatase Inhibitors (1)
- Aromatase inhibitors (1)
- Arrhythmia syndromes (1)
- Arrhythmia/all (1)
- Artemether-lumefantrine (1)
- Artemisinin-combination-therapy (1)
- Arteria ophthalmica (1)
- Arteriogenesis (1)
- Arteriosklerose (1)
- Arteriovenous malformation (1)
- Artesunate (1)
- Arthroplasty (1)
- Arthroscopy (1)
- Artificial feeding bioassays (1)
- Artificial iris (1)
- Arzneimittelmarkt (1)
- Arzneimittelrecht (1)
- Asian bush mosquito (1)
- Asparaginase (1)
- Aspergillosis (1)
- Aspergillus species (1)
- Aspirin (1)
- Assay variation (1)
- Assessment of care (1)
- Asthma (1)
- Asthma and allergic disorders (1)
- Astrocytoma (1)
- Astrocytoma grades (1)
- Ataxia score (1)
- Atazanavir (1)
- Atelopus carbonerensis (1)
- Atelopus mucubajiensis (1)
- Atelopus tamaense (1)
- Atezolizumab (1)
- Athlete (1)
- Atm (1)
- Atomoxetine (1)
- Atrial Fibrillation (1)
- Atrial appendage occlusion (1)
- Atrial fibrillation classification (1)
- Atrial function (1)
- Attack (1)
- Attention Deficit Hyperactivity Disorder (1)
- Attention Deficit Hyperactivity Disorder (ADHD) (1)
- Attention deficit (1)
- Attention-Deficit/Hyperactivity Disorder (ADHD) (1)
- Attention-deficit / hyperactivity disorder (1)
- Attentional bias (1)
- Atxn2 (1)
- Audio equipment (1)
- Audio signal processing (1)
- Audiology (1)
- Audition (1)
- Auditory (1)
- Auditory cortex (1)
- Auditory rehabilitation (1)
- Auric nanoparticles (1)
- Aurora (1)
- Aurora Ax (1)
- Aurora kinase (1)
- Aurora kinase inhibitor (1)
- Australia (1)
- Autism Spectrum disorder (1)
- Autism spectrum disorders (1)
- Autistic Behavior (1)
- Autistic disorder (1)
- Auto transfusion (1)
- Auto-ML (1)
- Autogenous bone block (1)
- Autoimmune encephalomyelitis (1)
- Autoimmune response (1)
- Autoimmune vasculopathy (1)
- Autologous stem cell transplantation (1)
- Automated Tube Potential Selection (1)
- Automated sRNA analysis (1)
- Automatic Environmental Tobacco Smoke Emitter (1)
- Automation (1)
- Autonomic nervous system (1)
- Autosomal recessive cutis laxa type 1C (1)
- Awareness (1)
- Axiography (1)
- Axon (1)
- Axons (1)
- Ayahuasca (1)
- Ayurveda (1)
- Ayurvedic herbal products (1)
- Azacitidine (1)
- Azan (1)
- Azan trichrome stain (1)
- Azathioprine (1)
- Azidothymidine (1)
- B cell cancer (1)
- B cell differentiation (1)
- B cell malignancies (1)
- B cell precursor acute lymphoblastic leukemia (1)
- B cell receptor (1)
- B cell subpopulations (1)
- B-cell (1)
- B-cell antigen receptor (1)
- B-cell immunology (1)
- B-cell non-Hodgkin lymphoma (1)
- B-cell receptor (1)
- B-cell transcription factors (1)
- B.1.1.529 (1)
- B.1.1.7 (1)
- B.1.617.1 (1)
- B.1.617.2 (1)
- B16 cells (1)
- B3GNT2 (1)
- BA.4 (1)
- BA.5 (1)
- BATF3 (1)
- BBB (1)
- BCL-2 (1)
- BCL11b (1)
- BCORL1 (1)
- BCR signaling (1)
- BCR-ABL (1)
- BEACOPP (1)
- BET proteins (1)
- BEZ235 (1)
- BFIS (1)
- BG-index (1)
- BH3 mimetics (1)
- BI1361849 (1)
- BIAM switch assay (1)
- BIAM-switch (1)
- BIRC5 (1)
- BK channel (1)
- BMAC (1)
- BMP4 (1)
- BMSC (1)
- BNC2 (1)
- BNT2b2 (1)
- BPD (1)
- BPDCN (1)
- BPO (1)
- BPTF (1)
- BRAF V600E (1)
- BRAF inhibitors (1)
- BRAF mutation (1)
- BRD4-NUT (1)
- BRUCE (1)
- BRVO (1)
- BTC (1)
- BTK (1)
- BV6 (1)
- Babesia venatorum (1)
- Bacillus subtilis (1)
- Back pain (1)
- Back scan (1)
- Backpropagating action potential (1)
- Bacteraemia (1)
- Bacteria (1)
- Bacteria-host interaction (1)
- Bacterial abundance (1)
- Bacterial adhesion (1)
- Bacterial leakage (1)
- Bacterial meningitis (1)
- Bacterial pathogenesis (1)
- Bacterial pathogens (1)
- BadA, (1)
- Bag6 (1)
- Balance (1)
- Ballet (1)
- Ballon-assisted enteroscopy (1)
- Balloon-expandable TAVI (1)
- Bamlanivimab (1)
- Bariatric surgery (1)
- Barlow disease (1)
- Barrier (1)
- Bartonella (1)
- Bartonella adhesin A (1)
- Bartonella grahamii (1)
- Bartonella henselae (1)
- Bartonella schoenbuchensis (1)
- Basal Ganglia (1)
- Basal ganglia (1)
- Bathyergidae (1)
- Batten disease (1)
- Bayesian (1)
- Bayesian inference (1)
- Bayesian model (1)
- Bcl-2 (1)
- Bcr-Abl (1)
- Beck Depression Inventory (1)
- Beckwith–Wiedemann syndrome (1)
- Becton Dickinson (1)
- Bee venom allergy (1)
- Beginners (1)
- Behandlungspfad (1)
- Behavioral analysis (1)
- Behavioral tests (1)
- Behavioural ecology (1)
- Benchmarks (1)
- Benign disorder (1)
- Benign enlargement of the subarachnoid spaces (BESS) (1)
- Benign prostatic hyperplasia (1)
- Bentall operation (1)
- Berci needle (1)
- Berotralstat (1)
- Best practice (1)
- Best-practice model (1)
- Bias (1)
- Bibliometric analysis (1)
- Biceps brachii (1)
- Bidirectional genes (1)
- Big Data (1)
- Big five (1)
- Bilateral cochlear implant (1)
- Bilateral sagittal split osteotomy (1)
- Biliary physiology (1)
- Biliary tree (1)
- Biliary tree stones (1)
- Bilirubin (1)
- Billroth II gastroenterostomy (1)
- Billroth papillotome (1)
- Billroth’s operation-II (1)
- Bio safety (1)
- Bioactivity-guided fractionation (1)
- Bioavailability prediction (1)
- Bioenergetics (1)
- Biofluids (1)
- Biological (1)
- Biological Activity (1)
- Biological heart valves (1)
- Biological invasion (1)
- Biological markers (1)
- Biological profile (1)
- Biological sciences (1)
- Biomarker Discovery Study (1)
- Biomarkers & Diagnostic Imaging (1)
- Biomechanical analysis (1)
- Biophysics (1)
- Bioprosthesis (1)
- Biotechnology (1)
- Bipolar (1)
- Birth (1)
- Bis-azido-NAD+ Analog (1)
- Bisphosphonates (1)
- Black cohosh (1)
- Black cohosh induced liver injury (1)
- Bleeding Risk (1)
- Blindness (1)
- Blocked occlusion (1)
- Blog (1)
- Blood cells (1)
- Blood coagulation disorder (1)
- Blood loss calculator (1)
- Blood loss formula (1)
- Blood management (1)
- Blood sample handling (1)
- Blood sampling (1)
- Blood transfusion (1)
- Bloodstream infection (1)
- Blow fly (1)
- Blowflies (1)
- BluePrint (1)
- Blurred vision (1)
- Blutspenderscreening (1)
- Blutung (1)
- Blutungskontrolle (1)
- Blutübertragbare Virusinfektionen (1)
- Body limbs (1)
- Body sway (1)
- Body-contouring surgery (1)
- Bone and joint mechanics (1)
- Bone cancer (1)
- Bone cement implantation syndrome (1)
- Bone conduction devices (1)
- Bone disease (1)
- Bone diseases (1)
- Bone diseases, Metabolic (1)
- Bone dust (1)
- Bone marrow aspirate concentrate (1)
- Bone marrow cells (1)
- Bone marrow fibrosis (1)
- Bone marrow mononuclear cells (1)
- Bone metastases (1)
- Bone metastasis (1)
- Bone remodelling (1)
- Bone strength assessment (1)
- Bone substitute (1)
- Bone tumor (1)
- Borrelia Garinii (1)
- Borrelia miyamotoi (1)
- Bortezomib (1)
- Bottom-up (1)
- Bowel obstruction (1)
- Brachial artery (1)
- Brachytherapy (1)
- Bradycardia (1)
- Bradykinin (1)
- Brain DNA methylation (1)
- Brain anatomy (1)
- Brain asymmetry (1)
- Brain damage (1)
- Brain development (1)
- Brain injuries (1)
- Brain injury (1)
- Brain ischemia (1)
- Brain repair (1)
- Brain tumor surgery (1)
- Brain tumors (1)
- BrainNet Europe consortium (1)
- Brasilien (1)
- Breast cancer survivers (1)
- Breast conserving surgery (1)
- Breast neoplasm (1)
- Breast reconstruction (1)
- Breathing (1)
- Breech delivery (1)
- Bright light therapy (1)
- Brij 35 (1)
- BrijL23 (1)
- Brms (1)
- Brodalumab (1)
- Bronchial inflammation (1)
- Bronchitis severity scale (1)
- Bronchodilator agents (1)
- Bronchopulmonary dysplasia (1)
- Browsertool (1)
- Brustkrebs (1)
- Bufonidae (1)
- Bungarus niger (1)
- Burkholderia arboris (1)
- Burkitt’s lymphoma (1)
- Burns (1)
- Burst (1)
- Bypass liner (1)
- C-clamp (1)
- C-reactive proteins (1)
- C1 esterase inhibitor (human) (1)
- C1-INH (C1 inhibitor, C1-esterase inhibitor) (1)
- C1-esterase inhibitor protein (1)
- C1-inhibitor (1)
- C1-inhibitor deficiency (1)
- C2 domain (1)
- C3M (1)
- C4M (1)
- C5 acylcarnitine (1)
- C57BL/6J mice (1)
- C57BL/6N mice (1)
- C6 ceramide (1)
- CA (1)
- CA1 (1)
- CAC-DRS Score (1)
- CAD-CAM (1)
- CAD/ CAM crown (1)
- CAD/CAM crown (1)
- CAKUT (1)
- CAPON (1)
- CAR-NK cell (1)
- CAR-T cell (1)
- CAT (1)
- CBC (1)
- CCC-2 (1)
- CCN2 (1)
- CD137 (1)
- CD23 (1)
- CD271 (1)
- CD3 (1)
- CD3/19 depletion (1)
- CD3/CD19 depletion (1)
- CD34 (1)
- CD34 selection (1)
- CD34+ cell enumeration (1)
- CD34 + cells (1)
- CD4 binding site (1)
- CD4+ T cells (1)
- CD40 (1)
- CD41 (1)
- CD45RA Depletion (1)
- CD45RA naïve lymphocytes (1)
- CD47 (1)
- CD49d (1)
- CD56 (1)
- CD62L (1)
- CD62P (1)
- CD62p+Exosomes (1)
- CD74 (1)
- CD8 (1)
- CD8+ T cell (1)
- CD8+ T cells (1)
- CD8+ T lymphocytes (1)
- CD8+ T-cell mediated tumor suppression (1)
- CD8+ tumor infiltrating lymphocytes (1)
- CD95/Fas receptor (1)
- CDH13 (1)
- CDI (1)
- CDK inhibitor (1)
- CDK-cyclin axis (1)
- CDK2 (1)
- CDK4/6 inhibitor (1)
- CDK4/6 inhibitors (1)
- CDK4/CDK6 (1)
- CDKN2A (1)
- CEBPD (1)
- CEBPE (1)
- CEST EPI (1)
- CGD (1)
- CGN codon (1)
- CHA2DS2-VASc-score (1)
- CHEPs (1)
- CHIP (1)
- CHRDL1 (1)
- CHRNA10 (1)
- CHRNA7 (1)
- CHRNA9 (1)
- CIK cell (1)
- CIM (1)
- CIRS (1)
- CK2α (1)
- CLEC-2 (1)
- CLIF-C ACLF score (1)
- CLIF-C ACLF-R score (1)
- CLOCC (1)
- CMS (1)
- CMVepidemiology (1)
- CNDAC (1)
- CNS (1)
- CNS cancer (1)
- CNS toxicity (1)
- CNS tumor (1)
- CNVs (1)
- CO2-induced forced ventilation (1)
- COBAS Taqman (1)
- COI (1)
- COII (1)
- COMT (1)
- COPD course and therapy (1)
- COVID (1)
- COVID 19 pandemic (1)
- COVID-19 epitope signatures (1)
- COVID-19 pandemic (1)
- COVID-19 vaccination (1)
- COVID-19, Primary care (1)
- COVID‐19 (1)
- CPT1A (1)
- CQL (1)
- CRBN (1)
- CRE-dependent transcription (1)
- CRE-luciferase (1)
- CREB inhibitor (1)
- CRISPR screen (1)
- CRISPR/dCas9 (1)
- CRM1 (1)
- CRPC (1)
- CRT (1)
- CRT-D (1)
- CRVO (1)
- CSC marker (1)
- CT dual-energy computed tomography (1)
- CT pulmonary angiography (1)
- CT radiation exposure (1)
- CT-guidance (1)
- CT-guided interventions (1)
- CTX (1)
- CUELA system (1)
- CUP (1)
- CVD biomarker (1)
- CVID (1)
- CWS Studiengruppe (1)
- CXCL10 (1)
- CXCL13 (1)
- CXCL16 (1)
- CXCR3 antagonism (1)
- CY-503 (1)
- CYBA/p22phox (1)
- CYP1A1 (1)
- CYP450 (1)
- Ca2+ imaging (1)
- CaMPARI (1)
- Cabozantinib (1)
- Caco 2 cells/metabolism (1)
- Caco-2 cells (1)
- Caco‐2 cells (1)
- Caenorhabditis elegans (1)
- Caffeine (1)
- Calcium calmodulin kinase (1)
- Calcium gluconate (1)
- Calcium signalling (1)
- Calciumphosphatprodukt (1)
- Calnexin (1)
- Calprotectin (1)
- Canada (1)
- Cancer Staging (1)
- Cancer detection (1)
- Cancer development (1)
- Cancer epigenetics (1)
- Cancer of unknown primary (1)
- Cancer progression (1)
- Cancer risk factors (1)
- Cancer staging (1)
- Cancer stem cells (1)
- Cancer survivors (1)
- Cancer therapeutic resistance (1)
- Cancer-specific survival (1)
- Candida spp (1)
- Capnography (1)
- Capsaicin (1)
- Capsule endoscopy, video (1)
- Carbapenem-resistente Gram-negative Bakterien (CRGN) (1)
- Carbapenemase (1)
- Carbapenemasen (1)
- Carbohydrates (1)
- Carbon tetrachloride (1)
- Carcinogenese (1)
- Carcinoma, Ductal, Breast (1)
- Cardiac (1)
- Cardiac Fibrosis (1)
- Cardiac acoustic biomarkers (1)
- Cardiac biomarkers (1)
- Cardiac device therapy (1)
- Cardiac fibroblast (1)
- Cardiac function (1)
- Cardiac implantable electronic devices (1)
- Cardiac infarction (1)
- Cardiac masses (1)
- Cardiac monitoring (1)
- Cardiac necroenzymes (1)
- Cardiac output (1)
- Cardiac rehabilitation (1)
- Cardiac remodeling (1)
- Cardiac remodelling (1)
- Cardiac resynchronization therapy (1)
- Cardiac surgery patients (1)
- Cardiac troponin (1)
- Cardio-oncology (1)
- CardioMEMS™ HF system (1)
- Cardiogenic shock (1)
- Cardiomyocyte signaling pathways (1)
- Cardiomyopathy (1)
- Cardiopulmonary bypass (1)
- Cardiotoxicity (1)
- Cardiovascular Magnetic Resonance (CMR) (1)
- Cardiovascular disease risk (1)
- Cardiovascular epidemiology (1)
- Cardiovascular genetics (1)
- Cardiovascular mortality (1)
- Cardiovaskuläre Erkrankungen (1)
- Care home (1)
- Career promotion (1)
- Careers (1)
- Carotid injury (1)
- Carrier-bound fibrin sealant (1)
- Cartilage (1)
- Cartilage Biology (1)
- Cas9 inhibitor (1)
- Case management [MeSH] (1)
- Casirivimab (1)
- Caspase-8 (1)
- Castleman’s disease (1)
- Catch-up validation study (1)
- Catheters (1)
- Catumaxomab (1)
- Causality (1)
- Causality assessment. (1)
- Cause of death (1)
- Cdk1/cyclin B1 (1)
- Cell Adhesion (1)
- Cell Biology (1)
- Cell Death (1)
- Cell Metabolism (1)
- Cell Migration (1)
- Cell Signaling (1)
- Cell Surface Receptor (1)
- Cell adhesion (1)
- Cell cortex (1)
- Cell cultures (1)
- Cell cycle (1)
- Cell distribution (1)
- Cell membranes (1)
- Cell metabolism (1)
- Cell motility (1)
- Cell plasticity (1)
- Cell processing (1)
- Cell surface proteoglycans (1)
- Cell-assisted lipotransfer (1)
- Cell-based Assays (1)
- Cell-based therapies (1)
- Cell-to-Cell Spread (1)
- Cellular (1)
- Cellular Immune Response (1)
- Cellular energy metabolism (1)
- Cellular imaging (1)
- Cellular inflammatory response (1)
- Cellular network formation (1)
- Cellular neuroscience (1)
- Cellular stress (1)
- Cellular stress responses (1)
- Cement gap (1)
- Cementation (1)
- Center-specific time in therapeutic range (cTTR) (1)
- Centers for Disease Control and Prevention (1)
- Central Europe (1)
- Central nervous system (1)
- Central nervous system metastases (1)
- Centrifugation (1)
- Ceramic (1)
- Ceramides (1)
- Cerasorb (1)
- Cerclage (1)
- Cerebellar ataxia (1)
- Cerebral Vasospasm (1)
- Cerebral cortex (1)
- Cerebral hypoperfusion (1)
- Cerebral ischemia (1)
- Cerebral oxygen saturation (1)
- Cerebral toxoplasmosis HIV (1)
- Cerebral vasospasm (1)
- Cerebrospinal Fluid (1)
- Cerebrovascular (1)
- Cerebrovascular disorders (1)
- Certification (1)
- Cervical (1)
- Cesarean delivery (1)
- Cezanne (1)
- ChAdOx1-S (1)
- Checkpoint Inhibitor (1)
- Checkpoint kinase (1)
- Checkpoints (1)
- Chemical company (1)
- Chemical ecology (1)
- Chemical labeling (1)
- Chemical modification (1)
- Chemiluminescence (1)
- Chemobrain (1)
- Chemoembolization (1)
- Chemokine CCL2 (1)
- Chemoprevention (1)
- Chemoradiation (1)
- Chemorefractory advanced gastric cancer (1)
- Chemosensitivity (1)
- Chest pain unit (1)
- Chikungunya (1)
- Chikungunya virus (1)
- Child abuse (1)
- Child adiposity (1)
- Child and adolescent psychotherapy (1)
- Children and adolescents (1)
- Chimeric Antigen Receptor (CAR) (1)
- Chimerism (1)
- Chinese crocodile lizard (1)
- Chlorides (1)
- Chloroform (1)
- Cholecystectomy (1)
- Cholesterin (1)
- Cholesterol (1)
- Cholinergic (1)
- Chondral Lesion (1)
- Chondrocyte (1)
- Chondrocyte signalling (1)
- Chorion (1)
- Chrna7 knockout (1)
- Chromatin and Epigenetics (1)
- Chromatin conformation (1)
- Chromodomains (1)
- Chromoendoscopy (1)
- Chromosom (1)
- Chromosomal deletion (1)
- Chronic Hepatitis C (1)
- Chronic ankle instability (1)
- Chronic care model (1)
- Chronic conditions (1)
- Chronic depression (1)
- Chronic disease [MeSH] (1)
- Chronic diseases (1)
- Chronic health condition (1)
- Chronic heart failure (1)
- Chronic hepatitis C virus (1)
- Chronic illness (1)
- Chronic infection (1)
- Chronic intestinal failure (1)
- Chronic lymphocytic leukemia (1)
- Chronic medical conditions (1)
- Chronic obstructive airway disease (1)
- Chronic pancreatitis (1)
- Chronic periodontiti (1)
- Chronification (1)
- Chronisch-myeloische Leukämie (1)
- Chronische Niereninsuffizienz (1)
- Chronology of disease (1)
- Cigarettes (1)
- Cine (1)
- Cinnarizine (1)
- Cinryze® (1)
- Circadian (1)
- Circadian rhythms and sleep (1)
- Circulating MiRNA (1)
- Circulation (1)
- Cirugía (1)
- Citation (1)
- Citationrate (1)
- Cities (1)
- Claudin 5 (1)
- Clavien–Dindo classification (1)
- Cleanliness level (1)
- Cleft palate (1)
- Click chemistry (1)
- Climate inequity (1)
- Clincial pharmacology (1)
- CliniMACS (1)
- Clinical (1)
- Clinical Skills (1)
- Clinical competence (1)
- Clinical effectiveness (1)
- Clinical efficacy (1)
- Clinical frailty scale (1)
- Clinical management (1)
- Clinical outcome (1)
- Clinical pathway (1)
- Clinical pathways (1)
- Clinical pharmacology (1)
- Clinical phenotype (1)
- Clinical practice guidelines (1)
- Clinical psychometry (1)
- Clinical skills (1)
- Clinical variation (1)
- Clip (1)
- Cln3 (1)
- Clonidine (1)
- Clostridioides difficile (1)
- Clostridium (1)
- Closure (1)
- ClpB (1)
- Cluster (1)
- Cluster randomization (1)
- Clustering (1)
- Co-culture (1)
- Co-morbidity (1)
- Coagulation (1)
- Coagulopathy management (1)
- Cochleaimplantation (1)
- Cochlear Implant (1)
- Coenzyme Analogue (1)
- Coenzyme Binding (1)
- Coeval folding and boudinage (1)
- Coexistence (1)
- Cofilin (1)
- Cognitive (1)
- Cognitive behavioural therapy (1)
- Cognitive dysfunction (1)
- Cognitive enhancers of exposure therapy (1)
- Cognitive neurology (1)
- Cognitive psychology (1)
- Coherent infomax (1)
- Cohort Analysis (1)
- Cohort study (1)
- Colchicum (1)
- Cold hardiness (1)
- Cold pain (1)
- Cold tolerance (1)
- Collagen Maps (1)
- Collagen antibody-induced arthritis (1)
- Collagen hemostat (1)
- Collagen type I (1)
- Collagen type III (1)
- Collagen-based biomaterial (1)
- Collagens (1)
- Colon cancer (1)
- Colon capsule endoscopy (1)
- Colonic neoplasms (1)
- Colonisation (1)
- Colony stimulating factor 1 receptor (1)
- Colorimetric blood loss estimation (1)
- Combined immune checkpoint blockade (1)
- Combined surgical therapy (1)
- Combo® DTS (1)
- Combustion (1)
- Communicable diseases (1)
- Comparative effectiveness research (1)
- Comparative study (1)
- Comparators (1)
- Compartmental modeling (1)
- Competencies (1)
- Complement Regulator (1)
- Complement cascade (1)
- Complement system (1)
- Complementary medicine (1)
- Complementation rate (1)
- Complete heart block (1)
- Complete response (1)
- Completed suicide (1)
- Complex Formation (1)
- Complex II (1)
- Complex Systems (1)
- Complex decongestive therapy (1)
- Complex elbow fractures (1)
- Complex hernia (1)
- Complex networks (1)
- Complexin 1 (1)
- Complexin-1 (1)
- Complexome profiling (1)
- Complicated stage (1)
- Complication (1)
- Comprehensive cancer centers (1)
- Comprehensive complication index (1)
- Compression stocking (1)
- Computational biology and bioinformatics (1)
- Computational biophysics (1)
- Computational model (1)
- Computational neuroscience (1)
- Computational sRNA analysis (1)
- Computational science (1)
- Computed axial tomography (1)
- Computed tomography imaging (1)
- Computed tomography pulmonary angiography (CTPA) (1)
- Computed tomography, X-ray (1)
- Computer simulation (1)
- Computer-Assisted (1)
- Computer-aided drug design (1)
- Computer-unterstützte (1)
- Computers (1)
- Concurrent CNS diseases (1)
- Concurrent chemoradiotherapy (1)
- Conditional gene trap (1)
- Conduct problems (1)
- Conduit function (1)
- Cone-beam computed tomography (1)
- Confinement (1)
- Confocal endomicroscopy (1)
- Conformational change (1)
- Congenital (1)
- Congenital CMVinfection (1)
- Congenital anomalies (1)
- Congenital diaphragmatic hernia (1)
- Congenital duodenal obstruction (1)
- Congenital ocular motor apraxia (1)
- Coniosporium corticale (1)
- Connectomics (1)
- Conometric connection (1)
- Consciousness (1)
- Consensus document (1)
- Consensus methods (1)
- Consensus statement (1)
- Conservative (1)
- Conservative treatment (1)
- Consortia (1)
- Constipation (1)
- Constitution (1)
- Constrained posture (1)
- Constriction (1)
- Contact precautions (1)
- Contingent Negative Variation, CNV (1)
- Continuous Performance Test, CPT (1)
- Continuous renal replacement therapy (1)
- Contractile function (1)
- Contrast agent (1)
- Contrast-Enhancing Lesions (1)
- Contrast-enhanced (1)
- Contrast-medium, injection rate, iodine concentration, hepatic malignancy, multiphasic CT (1)
- Control (1)
- Conventional Chemotherapeutic (1)
- Conventional and unconventional ubiquitination (1)
- Conventional dendritic cells (1)
- Conventional synthetic disease-modifying antirheumatic drug (1)
- Convolutional Neural Networks (1)
- Cooperation (1)
- Coping (1)
- Copy number (1)
- Copy number variation (1)
- Cord blood transplantation (1)
- Core needle biopsy (1)
- Cornea (1)
- Corneal tomography (1)
- Corona pandemic (1)
- Corona virus (1)
- Coronary CT (1)
- Coronary Heart Disease (1)
- Coronary Plaque Burden (1)
- Coronary artery disease (CAD) (1)
- Coronary calcification (1)
- Coronary intervention (1)
- Coronavirus (1)
- Coronaviruses (1)
- Cortical degeneration (1)
- Cortical thickness (1)
- Corucia zebrata (1)
- Cost-effectiveness analysis (1)
- Couch tracking (1)
- Council for International Organizations of Medical Sciences (1)
- Course (1)
- CoxVa (1)
- Coxibs (1)
- Craniomaxillofacial injuries (1)
- Credentialing (1)
- Crisis (1)
- Crispr/Cas (1)
- Critical Online Reasoning Assessment (1)
- Critical bleeding (1)
- Critical care and emergency medicine (1)
- Critical haematocrit (1)
- Critical pathway (1)
- Critical size (1)
- Cross-contamination (1)
- Cross-frequency coupling (1)
- Cross-sectional (1)
- Cross-sectional study (1)
- Crosscorrelation (1)
- Crossmodal (1)
- Cryo-electron microscopy (1)
- Cryoablation (1)
- Cryoballoon (1)
- Cryptococcus (1)
- Cryptostroma corticale (1)
- CspA (1)
- Cue-P3 (1)
- Culex pipiens (1)
- Culex pipiens biotypes pipiens/molestus (1)
- Culicidae (1)
- Culture positive (1)
- Cumulative dose (1)
- Curcumis sativus (1)
- Cure (1)
- Curvilinear dose response (1)
- Custom-made mouthguard (1)
- Cuticular hydrocarbons (1)
- Cyanoacrylate (1)
- CyberKnife (1)
- Cyclin T1 (1)
- Cyclosporin A (1)
- Cyp46a1 (1)
- Cystatin C (1)
- Cysteine‐Rich Domain (CRD) (1)
- Cytochrome P450 (1)
- Cytochrome P450 enzymes (1)
- Cytokine (1)
- Cytokines Induction (1)
- Cytology (1)
- Cytomegalovirus (CMV) (1)
- Cytoplasm (1)
- Cytoplasmic staining (1)
- Cytoreductive nephrectomy (1)
- Cytotoxic CD8+ T cell (1)
- Cytotoxicity (1)
- C‐reactive protein (1)
- D-amino acid oxidase (1)
- D-dimer (1)
- D2-autoreceptor (1)
- DAMP (1)
- DAMPs (1)
- DBH genotype (1)
- DBS (1)
- DC-NK cell interaction (1)
- DCK (1)
- DCM (1)
- DDA (1)
- DDIT4 (1)
- DECT (1)
- DEE (1)
- DFNB9 (1)
- DHA (1)
- DILI database case quality (1)
- DKK1 (1)
- DKTK-ROG (1)
- DLBCL (1)
- DMARDs (synthetic) (1)
- DME (1)
- DMXAA (1)
- DNA (1)
- DNA Adducts (1)
- DNA Damage (1)
- DNA double-strand break repair (1)
- DNA integrity (1)
- DNA repair (1)
- DNA replication (1)
- DNA sequence analysis (1)
- DNA sequencing (1)
- DNA-PK (1)
- DNA-based identification (1)
- DNA-binding proteins (1)
- DNA-protein crosslinks (1)
- DOK1 (1)
- DOMS (1)
- DPPIV (1)
- DR5 (1)
- DSAEK (1)
- DSS /AOM (1)
- DST (1)
- DTHR (1)
- DUBs (1)
- DVI (1)
- DWI (1)
- DYRK1A (1)
- DYT1 (1)
- Dabigatran (1)
- Dancer (1)
- Dark triad (1)
- Darunavir (1)
- Data Analysis (1)
- Data acquisition (1)
- Data mining (1)
- Data monitoring (1)
- Data preprocessing (1)
- Data reduction (1)
- Data structure detection (1)
- Data validation (1)
- Database (1)
- Database searching (1)
- Databases (1)
- Dataset bias (1)
- Daubert criteria (1)
- David technique (1)
- De-isolation (1)
- Dead space (1)
- Decision Confidence (1)
- Decision impact (1)
- Decision support (1)
- Decision-making (1)
- Decolonization (1)
- Decontamination (1)
- Deep learning (1)
- Deep neural network (1)
- Deep vein thrombosis (1)
- Defibrillation (1)
- Deficient Inhibition (1)
- Deformation (1)
- Deformation oblique layer (1)
- Degrader design (1)
- Dehydrogenase (1)
- Dehydrogenases (1)
- Delayed Cerebral Ischemia (1)
- Delayed union (1)
- Deletion mutation (1)
- Delivery mode (1)
- Delivery quality assurance (1)
- Delphi Survey (1)
- Delphi consensus (1)
- Dementia (1)
- Dendritic Cells (1)
- Dendritic cell (1)
- Dendritic cell population (1)
- Dendritic cells (1)
- Dendritic spines (1)
- Dendritische Zelle (1)
- Denervation (1)
- Dengue fever (1)
- Dengue virus (1)
- Density equalizing (1)
- Dental Tissues (1)
- Dental air (1)
- Dental casts (1)
- Dental education (1)
- Dental phobia (1)
- Dental practice (1)
- Dental training (1)
- Dentists (1)
- Dentition (1)
- Depolarization (1)
- Depression stigma (1)
- Dermal fat (1)
- Dermatitis (1)
- Dermatomyositis (1)
- Desinfektion von Flugzeugen (1)
- Desmin (1)
- Detection (1)
- Detection workflow (1)
- Developmental Biology (1)
- Developmental disorders (1)
- Developmental programming (1)
- Developmental trajectory (1)
- Developmentally adapted cognitive processing therapy (1)
- Devic disease (1)
- Devic syndrome (1)
- Device (1)
- Dexamethasone (1)
- Dexterity (1)
- Diabetic nephropathy (1)
- Diagnostic accuracy (1)
- Diagnostic differentiation (1)
- Diagnostic dye (1)
- Diagnostic error (1)
- Diagnostic techniques and procedures (1)
- Diagnostic tests (1)
- Diagnostics (1)
- Diagnostik (1)
- Diary Data (1)
- Dicer (1)
- Dichloromethane (1)
- Diesel (1)
- Diet (1)
- Dietary HDAC inhibitor (1)
- Dietary intake (1)
- Dietary supplements (1)
- Dieulafoy’s lesion (1)
- Differential Thermoanalysis (1)
- Differential expression (1)
- Difficult Airway Management (1)
- Diffuse astrocytoma (1)
- Diffuse large B cell lymphoma (1)
- Diffusion MRI (1)
- Diffusion magnetic resonance imaging (1)
- Digenic model (1)
- Digestive system (1)
- Digital (1)
- Digital breast tomosynthesis (DBT) (1)
- Digital hybrid visualization (1)
- Digital mammography (1)
- Digital pathology (1)
- Digital rectal examination (1)
- Digital subtraction angiography (1)
- Digital workshops (1)
- Dilated cardiomyopathy (1)
- Dimer (1)
- Dimers (Chemical physics) (1)
- Dimethyltryptamine (1)
- Dipeptide (1)
- Diphosphonates (1)
- Diphtheria (1)
- Diptera (1)
- Direct Acting Antivirals (DAA) (1)
- Direct acting antiviral therapies (1)
- Direct measurement (1)
- Direct oral anticoagulation (1)
- Direct-acting antiviral agents (DAAs) (1)
- Direct-acting antivirals (1)
- Disabilities (1)
- Disabling back pain (1)
- Disaster victim identification (1)
- Disc herniation (1)
- Discitis (1)
- Discovery (1)
- Discs large (1)
- Disease burden (1)
- Disease management (1)
- Disease progression (1)
- Disinfection of aircraft (1)
- Dislocations of the knee (1)
- Dissemination (1)
- Dissociative seizures (1)
- Distress (1)
- Distress screening (1)
- Distribution (1)
- Distribution limits (1)
- Dizygotic ectopic (1)
- Dog (1)
- Dogs (1)
- Dome-and-basin structure (1)
- Domestic (1)
- Donor Selection (1)
- Donor screening (1)
- Dorsal root ganglia (1)
- Dorsolateral prefrontal cortex (1)
- Dose optimization (1)
- Dot-probe task (1)
- Double balloon enteroscopy (1)
- Double-blind placebo-controlled trial (1)
- Doubling time (1)
- Down's syndrome (1)
- Downgrading (1)
- Doxorubicin (1)
- Dravet (1)
- Droplets (1)
- Drospirenon (1)
- Drug (1)
- Drug Discovery (1)
- Drug Therapy (1)
- Drug addiction (1)
- Drug discovery (1)
- Drug interactions (1)
- Drug permeability (1)
- Drug resistance/synergy (1)
- Drug screens (1)
- Drug susceptibility testing (1)
- Drug targeting (1)
- Drug targets (1)
- Dual energy CT (1)
- Dual therapy (1)
- Dual-Source CT (1)
- Dual-energy computed tomography (1)
- Duchenne’s muscular dystrophy (1)
- Dumon stents (1)
- Duodenal atresia (1)
- Duodenal stenosis (1)
- Duodenum (1)
- Dural onlays (1)
- Dvc1 (1)
- Dysfibrinogenämia (1)
- Dysfunctional social assumptions (1)
- Dysphagia (1)
- D’Amico classification (1)
- E protein structure (1)
- E-Learning (1)
- E-cadherin (1)
- E-cadhérine (1)
- E-health (1)
- E-learning (1)
- E. coli (1)
- E/I-Balance (1)
- E3-Ligases (1)
- EBM (1)
- EBRT (1)
- ECLS (1)
- ECM (1)
- EDB (1)
- EDOF (1)
- EDTA-plasma (1)
- EEG reference choices (1)
- EFP1 (1)
- EGF (1)
- EGFL7 (1)
- EGFP (1)
- EGFR inhibitor (1)
- EGFR pathway (1)
- EGFRvIII mutation (1)
- EGR1-dependent transcription (1)
- EHL concentrates (1)
- EIIIB (1)
- ELISPOT (1)
- ELSID-Diabetes (1)
- EMD 55900 (1)
- EMD 72000 (1)
- EMR1 (1)
- ENIGMA (1)
- EP300 (1)
- EPA (1)
- EQ (1)
- EQ5D5L (1)
- EQA scheme (1)
- EQIP (1)
- ER-phagy (1)
- ERAL1 (1)
- ERBB2 (1)
- ERBB2 (HER2/neu) (1)
- ERK inhibitor (1)
- ERK1/2 signaling (1)
- ERK3/MAPK6 (1)
- ERM (1)
- ERMS (1)
- ERSCongress (1)
- ES (1)
- ES cells (1)
- ESMO-MCBS (1)
- ESR Spectroscopy (1)
- ESR and Infrared Studies (1)
- ET (1)
- ETP-ALL (1)
- ETS (1)
- EVAR (1)
- EWS/Fli1 (1)
- EZ-IO® needle driver (1)
- Early (prenatal and postnatal) life experiences (1)
- Early Rheumatoid Arthritis (1)
- Early diagnosis (1)
- Early goal-directed therapy (1)
- Early intervention (1)
- Early recurrence (1)
- Early setting (1)
- Ebola (1)
- Ebola virus (1)
- Echocardiography (1)
- Echovirus-30 (1)
- Eclampsia (1)
- Ecological Momentary Assessment (EMA) (1)
- Ecological momentary assessment (1)
- Economic analysis (1)
- Economic benchmarks (1)
- Economic evaluation (1)
- Economic impact (1)
- Economics (1)
- Ectopic bone formation (1)
- Ectopic pregnancy (1)
- Ectopic varices (1)
- Edentulous jaw (1)
- Educación médica (1)
- Efavirenz (1)
- Effective connectivity (1)
- Effective half-life (1)
- Effectivity (1)
- Ego dissolution (1)
- Eicosanoids (1)
- Einreibetechnik (1)
- Elastogenesis (1)
- Elderly patients (1)
- Elderly trauma patient (1)
- Elective caesarean section (1)
- Electric stimulation (1)
- Electrical accident (1)
- Electrical instability (1)
- Electroconvulsive Therapy (1)
- Electroencephalography – EEG (1)
- Electrolytes (1)
- Electron transport chain (1)
- Electronic cigarettes (1)
- Electrotonic analysis (1)
- Elektroencephalographie (1)
- Elimination (1)
- Ellipsoids (1)
- Ellipticine (1)
- Elternurteil (1)
- Embolization (1)
- Embryos (1)
- Emergency (1)
- Emergency medicine (1)
- Emergency room (1)
- Emergency treatment (1)
- Emotion (1)
- Emotion processing (1)
- Emotional intelligence (1)
- Emotional recognition (1)
- Empfehlungen (1)
- Emphysema (1)
- Employment (1)
- Employment effect (1)
- Empty puparia (1)
- Ena/VASP proteins (1)
- Encephalitis Viruses (1)
- End-of-life decisions (1)
- Endocrine cancer (1)
- Endocrine system and metabolic diseases (1)
- Endocrine therapy (1)
- Endogenous retroviruses (ERV) (1)
- Endoluminal (1)
- Endometrial cancer (1)
- Endometrial carcinoma (1)
- Endometriosis (1)
- Endomicroscopy (1)
- Endoplasmic reticulum (1)
- Endorectal (1)
- Endoscopic papillotomy (1)
- Endoscopic retrograde Cholangiopancreatography (ERCP) (1)
- Endoscopic retrograde cholangiography (1)
- Endoscopic sphincterotomy (1)
- Endoscopic treatment (1)
- Endosomes (1)
- Endothelial (1)
- Endothelial cell (EC) (1)
- Endothelial nitric oxide synthase (1)
- Endothelial progenitor cells (1)
- Endothelial protein C receptor (1)
- Endothelial-to-mesenchymal transition (1)
- Endotoxins (1)
- Endovascular aortic repair (1)
- Endpoints (1)
- Energy (1)
- Energy metabolism (1)
- Energy-efficiency (1)
- England (1)
- Engraftment (1)
- Enteral nutrition (1)
- Enteric nervous system (1)
- Enterobacterales (1)
- Enterostomy (1)
- Enterostomy closure (1)
- Enterostomy formation (1)
- Entfernung (1)
- Entorhinal cortex lesion (1)
- Entrenamiento práctico (1)
- EnvZ signalling (1)
- Envenomation (1)
- Environmental biotechnology (1)
- Environmental chemistry (1)
- Environmental enrichment (1)
- Environmental impacts (1)
- Environmental sciences (1)
- Enzyme kinetics (1)
- Enzyme mechanisms (1)
- Enzyme regulation (1)
- Eosinophils (1)
- EpCAM positive tumor (1)
- Ephrin-B2–EphB4 (1)
- Epidemiological data (1)
- Epidermolysis bullosa simplex with muscular dystrophy (1)
- Epidural abscess (1)
- Epidural block (1)
- Epilepsiezentren (1)
- Epilepsy center (1)
- Epilepsy centers (1)
- Epileptischer Anfall (1)
- Epithelial cells (1)
- Epithelialization (1)
- Epithelioma Cells (1)
- Epsilon (1)
- Epstein–Barr virus (1)
- Equipment (1)
- Eradication (1)
- ErbB-signaling (1)
- Erythema migrans (1)
- Erythrocytes (1)
- Erythrophagocytosis (1)
- Erythropoiesis (1)
- Esophageal adenocarcinoma (1)
- Esophageal adenocarcinoma (EAC) (1)
- Esophagectomy (1)
- Esophagogastric (1)
- Estimated glomerular filtration rate (1)
- Estradiol (1)
- Estrogen Receptor Modulators (1)
- Etanercept (1)
- Ethnicity (1)
- Eukaryotic sRNA (1)
- European Society for Immunodeficiencies (ESID) (1)
- European babesiosis (1)
- European registry for idiopathic pulmonary fibrosis (eurIPFreg) (1)
- Europäische Integration (1)
- Europäische Union (1)
- Euthanasie (1)
- Euthymic phase (1)
- Evaluation in microsurgery (1)
- Event related potentials (1)
- Event-related potential (1)
- Everolimus resistance (1)
- Evidence based medicine (1)
- Evidence-based (1)
- Evidence-based drug discovery (1)
- Evidence-based guidelines (1)
- Evidenz (1)
- Evidenzbasiert (1)
- Evolutionary biology (1)
- Ewing-like (1)
- Exacerbations (1)
- Examination questions (1)
- Excitability (1)
- Exemestane (1)
- Exercise challenge (1)
- Exercise challenge at an ambient temperature (1)
- Exercise challenge in a cold chamber (1)
- Exercise testing (1)
- Exercise therapy (1)
- Exercise training (1)
- Exercise-induced asthma (1)
- Exercise-induced bronchoconstriction (1)
- Exertional angina and myocardial perfusion (1)
- Exhaled nitric oxide (1)
- Exoscope (1)
- Exosomal cytokines (1)
- Expansion (1)
- Expectation violation (1)
- Experimental autoimmune encephalomyelitis (1)
- Expert Systems (1)
- Expertensysteme (1)
- Experts (1)
- Explicit (1)
- Expression (1)
- Extended Glasgow outcome scale (eGOS) (1)
- Extension study (1)
- External beam radiotherapy (1)
- External-/self-assessment (1)
- Extinction (1)
- Extracellular RNA (1)
- Extracellular RNA (eRNA) (1)
- Extracellular signal-regulated kinase 1/2 (1)
- Extracorporeal circulation (1)
- Extracorporeal devices (1)
- Extracorporeal life support (1)
- Extracorporeal membrane oxygenation (1)
- Extracorporeal purification (1)
- Extraprostatic (1)
- Extreme hypo-fractionation (1)
- Exudates and transudates (1)
- F4/80 (1)
- F508del homozygous (1)
- FAAM (1)
- FABP (1)
- FAIR (1)
- FAK (1)
- FAM134 (1)
- FAM134B (1)
- FAP (1)
- FAPI PET (1)
- FAV00A (1)
- FBK-R23 (1)
- FDG-PET/CT (1)
- FF-ATP synthase dimer (1)
- FFP3 respirator (1)
- FHIR Search (1)
- FIB-4 (1)
- FIH1 (1)
- FLT3 (1)
- FOLFIRI (1)
- FOXO1 (1)
- FOXO3 (1)
- FOXO3a (1)
- FPR (1)
- FREEDOM (1)
- FSME-Virus (1)
- FSS (1)
- FTMT (1)
- FX06 (1)
- FXR (1)
- Face masks (1)
- Facet joint osteoarthritis (1)
- Facial nerve (1)
- Factor H (1)
- Factor analysis (1)
- FactorXIII Val34Leu polymorphism (1)
- Faktor V Leiden Mutation (1)
- Faktor XIII Val34Leu Polymorphismus (1)
- Falciparum (1)
- Fall (1)
- Falls (1)
- Family Physician (1)
- Famines (1)
- Fascia (1)
- Fast Healthcare Interoperability Resources (1)
- Fast-track (1)
- Fat layer (1)
- Fatty acids (1)
- Fbw7 (1)
- Fc receptor (1)
- Fear conditioning (1)
- Feasibility studies (1)
- Feature tracking (1)
- Feedback loop (1)
- Fehlerberichtssystem (1)
- Feline bartonellosis (1)
- FemNAT-CD (1)
- Female (1)
- Female adolescents (1)
- Female subjects (1)
- Females (1)
- Femoral neck (1)
- Fendrr (1)
- Ferritinophagy (1)
- Ferroptosis (1)
- Fertility counseling (1)
- Fetal bovine serum (1)
- Fetal heart (1)
- Fever (1)
- Fevers (1)
- Fibrinolytic (1)
- Fibroblast (1)
- Fibroblast growth factor (1)
- Fibrotest (1)
- Fibrous dysplasia (1)
- Fibulin-4 (1)
- Fibulin-5 (1)
- Field study (1)
- Filariasis (1)
- Filariosis (1)
- Filgrastim (1)
- Filler (1)
- Filovirus cell entry; attachment factors redundancy; SH-SY5Y cell line; host–pathogen interactions (1)
- Finevo (1)
- Finite Element Method (1)
- First experience with patients (1)
- First site of metastatic disease (1)
- First-line combination antiretroviral therapy (1)
- First-line regimen (1)
- Five-Konzept (1)
- Flavin mononucleotide (1)
- Fleas (1)
- FlexTouch (1)
- Flexibility (1)
- Flexible Endoscopic Evaluation of Swallowing (1)
- Fluid overload (1)
- Fluid therapy (1)
- Fluorescence (1)
- Fluorescence imaging (1)
- Fluorescence-in-situ-hybridization (FISH) (1)
- Fluorescent Probes (1)
- Foam rolling (1)
- Focal Adhesion Kinase (1)
- Focal onset seizure (1)
- Folic acid (1)
- Follicular lymphoma (1)
- Follow-up (1)
- Follow-up treatment (1)
- Follow-ups (1)
- Fondaparinux (1)
- Food and Drug Administration (1)
- Food effects (1)
- Foramen ovale (1)
- Forced expiratory volume in 1 s (1)
- Forensic examination (1)
- Forensic experts (1)
- Forensic pathology (1)
- Forensics (1)
- Forkhead box (1)
- Formation dance (1)
- Foxp1 (1)
- Fracture (1)
- Fracture models (1)
- Fracture risk (1)
- Fracture type (1)
- Frameshift (1)
- Francisella tularensis (1)
- Francisella tularensis subspecies holarctica (1)
- Frankfurt microsurgery course (1)
- Fresh frozen plasma (1)
- Frontobasal (1)
- Frontotemporal dementia (1)
- Fruit fly (1)
- Früherkennung (1)
- Frühgeborenes (1)
- Frühsommermeningoenzephalitis (1)
- Fuctional connectivity (1)
- Fukushima (1)
- Functional ankle instability (1)
- Functional capacity (1)
- Functional mitral regurgitation (1)
- Functional outcome (1)
- Functional outcomes (1)
- Functionally-impaired elderly (1)
- Funding (1)
- FungiScope® registry (1)
- Funktionelle Bildgebung (1)
- Funktionelle NMR-Tomographie (1)
- Fusarium (1)
- Fusion Proteins, BCR-ABL (1)
- G-protein (1)
- G-protein-coupled receptors (1)
- G/P (1)
- G207 (1)
- G3BP (1)
- G3BP1 (1)
- G9a/EHMT2/KMT1C (1)
- GABA (1)
- GABAergic interneurons (1)
- GC–MS (1)
- GD2 (1)
- GDF11 (1)
- GFR (1)
- GHQ-28 (1)
- GIIb/IIIa-receptor (1)
- GLA deficiency (1)
- GLI inhibitors (1)
- GLUT1 (1)
- GM-CSF (1)
- GMP (1)
- GPR4 (1)
- GPVI (1)
- GRADE (1)
- GRAND-SLAM (1)
- GRK2 (1)
- GRX1-roGFP2 (1)
- GSH (1)
- GSK2334470 (1)
- GSK3α (1)
- GSK3β (1)
- GTP cyclohydrolase (1)
- GVHD (1)
- GVL (1)
- Gaba (1)
- Gadopentate dimeglumine (1)
- Gads (1)
- Galaktografie (1)
- Galaktomosynthese (1)
- Gallbladder percutaneous drainage (1)
- Galleria mellonella (1)
- Games (1)
- Gamma-Band Activity (1)
- Gamma-aminobutyric acid (1)
- Ganglionic (1)
- Ganzheitsmedizin (1)
- Gan–Dou–Fu–Mu decoction (GDFMD) (1)
- Gap junctions (1)
- Gas gangrene (1)
- Gastric adenoma (1)
- Gastric motility (1)
- Gastroenterology (1)
- Gastroesophageal reflux disease (1)
- Gastroesophageal reflux disease symptoms (1)
- Gastrointestinal (1)
- Gastrointestinal cancer (1)
- Gastrointestinal neoplasm (1)
- Gastrointestinal tract (1)
- Gastroschisis (1)
- Gaucher disease type III (1)
- Gaucher’s disease (1)
- Gaussian graphical models (1)
- Gemcitabine (1)
- Gender analysis (1)
- Gender equality (1)
- Gender gap (1)
- Gender reassigning surgery (1)
- Gene (1)
- Gene engineering (1)
- Gene expression prediction (1)
- Gene microarray analysis (1)
- Gene polymorphism (1)
- Gene prediction (1)
- Gene sequencing (1)
- Gene set analysis (1)
- Gene-protein assay (1)
- Gene/Regulation (1)
- GeneMANIA (1)
- General Practitioner (1)
- General clinical cardiology (1)
- General dental practice (1)
- General practice/family medicine (1)
- General practitioner (1)
- Generalized procrustes analysis (1)
- Generation Y (1)
- Generation time (1)
- Generic drugs (1)
- Genetic causes of cancer (1)
- Genetic heart disease (1)
- Genetic loci (1)
- Genetic networks (1)
- Genetic syndromes (1)
- Genetic techniques (1)
- Genetik (1)
- Genfamilie (1)
- Genome annotation (1)
- Genome editing (1)
- Genome-wide association study (1)
- Genomic instability (1)
- Genomic medicine (1)
- Geographical disparities (1)
- Gerinnungsfaktor XIII (1)
- German (1)
- German PID-NET registry (1)
- Geschlecht (1)
- Gestagen-Monopräparate (1)
- Gestational age (1)
- Gestational diabetes (1)
- Gesundheitsamt (1)
- Gesundheitspolitische Zuständigkeit (1)
- Gesundheitswesen (1)
- Gezielte Therapie (1)
- Giant lymph node hyperplasia (1)
- Gimbaled tracking (1)
- Glabella (1)
- Gleason Grade Group (1)
- Gleason Grade group (1)
- Gleason Score (1)
- Gleason grade group (1)
- Gleason upgrading (1)
- Glioblastoma survival (1)
- Glivec® (1)
- Global networking (1)
- Global protein synthesis rates (1)
- Global warming (1)
- Glomerular Filtration Rate (1)
- Glomerular diseases (1)
- Glomerulonephritis (1)
- Glomerulosclerosis (1)
- Glucocorticoids (1)
- Glucose Transporter Type 1 (1)
- Glycogen synthase kinase 3 beta (1)
- Glycosphingolipids (1)
- Glyoxalase I (1)
- Goal-oriented care (1)
- Gold (1)
- Goserelin (1)
- Gradient boosting (1)
- Grading (1)
- Grado en medicina (1)
- Graft (1)
- Graft function (1)
- Graft quality (1)
- Graft survival (1)
- Gram negative bacteria (1)
- Gram-negative bacteria (1)
- Gram-positive infection (1)
- Granule cell (1)
- Granulocytes (1)
- Graph Machine Learning (1)
- Graph Neural Networks (1)
- Graph theory (1)
- Graphical LASSO (1)
- Grass pollen (1)
- Graves’ disease (1)
- Gravimetric method (1)
- Greater tuberosity fractures (1)
- Green arboreal alligator lizard (1)
- Greenhouse effect (1)
- Groin pain (1)
- Gross tumor volume optimization (1)
- Growth cone (1)
- Growth factor (1)
- Growth factor signalling (1)
- Großhirnrinde (1)
- Guidance (1)
- Guide profession (1)
- Guided bone regeneration (GBR) (1)
- Guided surgery (1)
- Guided tissue regeneration (1)
- Guided tissue regeneration (GTR) (1)
- Guideline adherence (1)
- Gut (1)
- Gut bacteria (1)
- Gut-liver-axis (1)
- GvHD (1)
- GvL (1)
- Gαq/11 (1)
- H-Index (1)
- H3 receptor (1)
- H5N1 (1)
- HACA (1)
- HADS (1)
- HAEGARDA (1)
- HAI‐1 (1)
- HARS2 (1)
- HBV filaments (1)
- HBV genotypes (1)
- HBV reactivation (1)
- HBV surface protein (1)
- HBsAg (1)
- HCC marker (1)
- HCC recurrence (1)
- HCV treatment (1)
- HDAC and BET inhibitor (1)
- HDAC-inhibition (1)
- HDAC4 (1)
- HDR-brachytherapy (1)
- HEOR (1)
- HER2 c-erbB2 (1)
- HER2-positive (1)
- HER2/neu (ERBB2) (1)
- HES (1)
- HEV (1)
- HFrEF (1)
- HGF (1)
- HH (1)
- HIBCPP cells (1)
- HIF-1α (1)
- HIF-2 (1)
- HIF-2α (1)
- HIF-2α, erythropoietin (1)
- HIF1α (1)
- HIFU (1)
- HILI (1)
- HIPPO signalling (1)
- HIV serodiagnosis (1)
- HIV therapy (1)
- HIV-1 escape restriction (1)
- HIV-RNA (1)
- HLA DQ haplotypes (1)
- HLA antibodies (1)
- HLA class I loss (1)
- HLA class II (1)
- HLA peptidome (1)
- HLHS (1)
- HMA (1)
- HMGB1 (1)
- HNPCC (1)
- HODE (1)
- HOLEP (1)
- HOSO (1)
- HOTAIR (1)
- HPO (1)
- HPV infection (1)
- HPV-positive OPSCC (1)
- HRCT (1)
- HRas (1)
- HSC (1)
- HSP (hereditary spastic paraplegia) (1)
- HSPC (1)
- HSV type specific antibodies (1)
- HSV-2 (1)
- HSV-typenspezifische Antikörper (1)
- HT22 neurons (1)
- HUVEC (1)
- HVPG (1)
- Haematocrit (1)
- Haematologic diseases (1)
- Haematoma expansion (1)
- Haematopoietic stem cells (1)
- Haemodialysis (1)
- Haemodynamic monitoring (1)
- Haemophilia (1)
- Haemophilie A (1)
- Haemostatics (1)
- Halogenobenzimidazoles (1)
- Hand-foot syndrome (1)
- Haploidentical stem cell transplantation (1)
- Haplotypes (1)
- Hard-tissue trauma (1)
- Hard-to-reach population (1)
- Hardware erosion (1)
- Hashimoto’s thyroiditis (1)
- Hawaii Department of Health (1)
- HbA1c (1)
- HeLa cells (1)
- Head and neck Cancer (1)
- Head bandage (1)
- Head injury (1)
- Head neck cancer (1)
- Health Policy (1)
- Health Systems (1)
- Health care access (1)
- Health care resource utilization (1)
- Health care sector (1)
- Health education and awareness (1)
- Health information (1)
- Health literacy (1)
- Health risk analysis (1)
- Health sciences (1)
- Health services research [MeSH] (1)
- Health surveys (1)
- Health technology assessment (1)
- Health-related quality of life (1)
- Health-seeking behaviour (1)
- Healthcare (1)
- Healthcare personnel (1)
- Healthcare resource utilisation (1)
- Healthcare structure (1)
- Healthy Living Index (HLI) (1)
- Healthy men (1)
- Healthy stem cell donors (1)
- Health‐related quality of life (1)
- Heart defects (1)
- Heart rate (1)
- Heart regeneration (1)
- Heartrate (1)
- Heat Shock Protein (HSP) (1)
- Heat dissipation (1)
- Heat pain (1)
- Heat shock protein 27 (1)
- Hebbian plasticity (1)
- Hedgehog (1)
- Hedgehog pathway (1)
- Helpline (1)
- Hemagglutination inhibition assay (1)
- Hematocrit value (1)
- Hematologic adverse events (1)
- Hematoma (1)
- Hematopoietic stem and progenitor cells (HSPCs) (1)
- Hematopoietic stem cell (1)
- Hematopoietic stem cell transplant (1)
- Hematopoietic stem cell transplantation (1)
- Hematopoietic stem cells (1)
- Hematotoxicity (1)
- Hematoxylin staining (1)
- Hemispheric specialization (1)
- Hemobilia (1)
- Hemodialyse (1)
- Hemodilution (1)
- Hemodynamic management (1)
- Hemoglobin (1)
- Hemophilia A (1)
- Hemorrhagic shock (1)
- Hemosiderin (1)
- Hemostasis (1)
- Hemostatics (1)
- HepaRG cells (1)
- Heparan Sulfate (1)
- Heparinsensitivität (1)
- Hepatic encephalopathy (1)
- Hepatic stellate cell (1)
- Hepatitis B (1)
- Hepatitis B infection (1)
- Hepatitis B vaccination (1)
- Hepatitis B virus (1)
- Hepatitis C antibodies (1)
- Hepatitis C antigens (1)
- Hepatitis C, Chronic (1)
- Hepatitis c (1)
- Hepatocellular carcinoma (HCC) (1)
- Herbal medicine (1)
- Herbalife (1)
- Herbalife products (1)
- Herbs (1)
- Herbs induced liver injury (1)
- Herd immunity (1)
- Hereditary breast and ovarian cancer (1)
- Hereditary breast cancer (1)
- Hereditary ovarian cancer (1)
- Heregulin (1)
- Hernia recurrence (1)
- Hernia surgery (1)
- Herniated disk (1)
- Herpes Zoster Infektion (1)
- Heterologous prime-boost (1)
- Heterotopic pregnancy (1)
- Hexavalent vaccine (1)
- HhAntag (1)
- HiC (1)
- HiChIP (1)
- Hierarchical drift-diffusion modeling (1)
- Hif-1 alpha (1)
- Hif1α (1)
- Hig1 (1)
- High altitude (1)
- High-dose chemotherapy (1)
- High-income countries (1)
- High-intensity interval endurance training (1)
- High-risk cardiac surgery (1)
- High-risk patient (1)
- High-risk prostate cancer (1)
- High-throughput screening (1)
- Highly infectious diseases (1)
- Highwire (1)
- Himalayas (1)
- Hindu Kush Himalayas (1)
- Hip (1)
- Hip hemiarthroplasty (1)
- Hip revision (1)
- Hippo signaling (1)
- Hippocampal excitability (1)
- Hippocampal volume (1)
- Hirnforschung (1)
- Hirschsprung disease (1)
- Hispanic people (1)
- Hispanic–Latino race/ethnicity (1)
- Histological analysis (1)
- Histone post-translational modifications (1)
- Histoplasma qPCR (1)
- Hmox1 (1)
- Hochansteckende Krankheiten (1)
- Hodgkin’s lymphoma (1)
- Holmium laser enucleation (1)
- Home Care Services [MeSH] (1)
- Homeostatic plasticity (1)
- Homicide (1)
- Homocysteine (1)
- Honolulu Queen’s Medical Center (1)
- Hormonal (1)
- Hormone receptor positive breast cancer (1)
- Horner's syndrome (1)
- Horses (1)
- Hospitalization (1)
- Hospitalizations (1)
- Host-directed therapies (1)
- Host-targeting agents (HTAs) (1)
- House dust mite allergy (1)
- Household contacts (1)
- Hrvaška (1)
- Hsp70 (1)
- Hsp90 inhibitor (1)
- HuR (1)
- Huh7 (1)
- Human (1)
- Human chorionic villi mesenchymal stromal cells (1)
- Human experimental pain models (1)
- Human immunodeficiency virus (HIV) (1)
- Human olfaction (1)
- Human pancreas (1)
- Human physiology (1)
- Human primary proximal tubular cells (1)
- Human prostate (1)
- Human retroelements (1)
- Human visual cortex (1)
- Humans (1)
- Humeral fractures (1)
- Humerus (1)
- Hungary (1)
- Hyaluronan (1)
- Hydrocephalus (1)
- Hydrofluoric acid (1)
- Hydromineral (1)
- Hydroxyapatite (1)
- Hydroxychloroquine (1)
- Hydroxycut (1)
- Hydroxyethyl starch (1)
- Hydroxyurea (1)
- Hymenoptera venom allergy (1)
- Hymenoptera venom immunotherapy (1)
- Hyperactivity (1)
- Hyperammonemic encephalopathy (1)
- Hyperscanning (1)
- Hypertensive disorders in pregnancy (1)
- Hypofractionated radiotherapy (1)
- Hyponatremia (1)
- Hypoxia inducible factor (1)
- Hypoxia inducible factor 1 alphal (1)
- Hypoxia-inducible factor-1α (HIF-1α) (1)
- Hypoxic responses (1)
- Hörrehabilitation (1)
- Hörrinde (1)
- I-FABP (1)
- I-PRF (1)
- IAP (1)
- IAP Proteins (1)
- IAP-IAP (1)
- ICAM-1 (1)
- ICG (1)
- ICH M13A draft guideline (1)
- ICL (1)
- ICL V4c (1)
- IDH1 inhibitor (1)
- IDO1 (1)
- IFA (1)
- IFN (1)
- IFN-β (1)
- IFN-γ expression (1)
- IFT (1)
- IGF (1)
- IGF-1 (1)
- IGF1 (1)
- IGRA (1)
- IKKε (1)
- IKZF1 (1)
- IL -17 (1)
- IL -23 (1)
- IL 23p19 knockout mouse (1)
- IL-11 (1)
- IL-13 (1)
- IL-15 (1)
- IL-17 (1)
- IL-17A (1)
- IL-18 binding protein (1)
- IL-18BP (1)
- IL-1b (1)
- IL-21 (1)
- IL-22 (1)
- IL-23 (1)
- IL-27 cytokine (1)
- IL-38 (1)
- IL10R (1)
- ILUVIEN (1)
- IMiD® (1)
- INR (1)
- IOL scleral Fixation (1)
- IPEX (1)
- IPS e.max system (1)
- IPSS (1)
- IR (1)
- IRES translation (1)
- IRF-3 (1)
- ISS (1)
- ITGA7 (1)
- IUIS classification 2017 (1)
- IV iron (1)
- IVA interference tandem mass spectrometry (1)
- IVD degeneration (IVDD) (1)
- IVDU (1)
- IVUS (1)
- Iceland (1)
- Idarucizumab (1)
- Idelalisib (1)
- Identifier (1)
- Identifikation (1)
- Identifizierung von Katastrophenopfern (1)
- Identity (1)
- Idiopathic pulmonary fibrosis (IPF) (1)
- IgA deficiency (1)
- IgE (1)
- IgG (1)
- IgG substitution therapy (1)
- IgG4-related disease (1)
- IgGAM (1)
- Ileostomy (1)
- Ileus (1)
- Illumina (1)
- Image processing (computer-assisted) (1)
- Imagery (1)
- Imaging (1)
- Imaging genetics (1)
- Imaging in LGG (1)
- Imaging, three-dimensional (1)
- Imatinib mesilat (1)
- Imdevimab (1)
- Immediate loading (1)
- Immediate placement (1)
- Immobilization (1)
- Immunbiology (1)
- Immune Response (1)
- Immune checkpoint inhibitors (1)
- Immune complex vasculitis (1)
- Immune paralysis (1)
- Immune receptor signaling (1)
- Immune response (1)
- Immune status (1)
- Immunität (Medizin) (1)
- Immunität <Medizin> (1)
- Immunoassay (1)
- Immunoassays (1)
- Immunocompromised (1)
- Immunodeficiency (1)
- Immunogenetics (1)
- Immunoglobulin Therapy (1)
- Immunoglobulins (1)
- Immunohistochemistry techniques (1)
- Immunological techniques (1)
- Immunology and Microbiology Section (1)
- Immunomodulatory agents (1)
- Immunomonitoring (1)
- Immunophenotyping (1)
- Immunosenescence (1)
- Immunostaining (1)
- Immunosuppressive Agents (1)
- Immunosuppressive agents (1)
- Immunosuppressive therapy (1)
- Immuno‑histochemistry (1)
- Impella (1)
- Impfraten (1)
- Impfstoff (1)
- Impfung (1)
- Implant osseointegration (1)
- Implant-supported bars (1)
- Implantable cardioverter-defibrillator (1)
- Implementación (1)
- Implicit (1)
- Implicit Processing (1)
- Implicit Association Test (1)
- Implicit motives (1)
- Impoverishment (1)
- Impulse control (1)
- Impulse generator (1)
- Imrt (1)
- In vivo electrophysiology (1)
- In-Hospital Emergencies (1)
- In-TIPS thrombosis (1)
- In-hospital cardiac arrest (1)
- In-line filtration (1)
- In-vivo (1)
- Inactivation (1)
- IncL (1)
- IncX (1)
- Incident reporting system (1)
- Incidental prostate cancer (1)
- Incomplete colonoscopy (1)
- Incontinence (1)
- Independent component analysis (1)
- Independent laboratories (1)
- Indeterminate biliary stricture (1)
- Index (1)
- Indication (1)
- Indication for fertility preservation (1)
- Indirect treatment comparison (ITC) (1)
- Individual differences (1)
- Individualized intervention (1)
- Individualized therapy (1)
- Indocyanine green (1)
- Indoor air pollution (1)
- Induced membrane technique (1)
- Induced pluripotent stem cells (1)
- Induced sputum (1)
- Inducible nitric oxide synthase (iNOS) (1)
- Induction therapy (1)
- Inequality (1)
- Infant (1)
- Infant leukemia (1)
- Infants (1)
- Infarction (1)
- Infectious disease (1)
- Infectious disease epidemiology (1)
- Infektionsserologie (1)
- Inferior vena cava thrombus (1)
- Inflammasome (1)
- Inflammatory fibroid polyp (1)
- Inflammatory pattern (1)
- Infliximab (1)
- Inflow obstruction (1)
- Influenza vaccination (1)
- Information transfer (1)
- Infrared Raman (1)
- Infusion management (1)
- Inguinal hernia (1)
- Inguinal pain (1)
- Inherited arrhythmic syndrome (1)
- Injury Severity Score (ISS) (1)
- Inner ear therapy (1)
- Inpatient hospital cases (1)
- Inpatients (1)
- Inside-out Signaling (1)
- Insula (1)
- Insulin resistance (1)
- Insulin secretion (1)
- Insulin therapy (1)
- Integrated Pulmonary Index (1)
- Integrated multimodal training (1)
- Integrative Network Analysis (1)
- Integrins (1)
- Intelligence (1)
- Intelligence tests (1)
- Intensive care outcome (1)
- Intensive care unit (1)
- Intention attribution (1)
- Inter-study reproducibility (1)
- Interaction (1)
- Interdisciplinarity (1)
- Interferon-free HCV treatment (1)
- Interferon-α (1)
- Interferon-λ, (1)
- Interferons (1)
- Interleukin-10 (1)
- Interleukin-17A (1)
- Interleukin-18 (1)
- Interleukin-18 binding protein (1)
- Interleukin-22 binding protein (1)
- Interleukin-36 (1)
- Intermediate filaments (1)
- Intermediate-risk (1)
- International body passport (1)
- International normalized ratio (1)
- Internationaler Vergleich (1)
- Internet citation (1)
- Internet-based therapy (1)
- Interoperability (1)
- Interposition (1)
- Interpretation Bias (1)
- Intersectoral care (1)
- Interspecific competition (1)
- Interstitial lung diseases (ILD) (1)
- Interstitial pneumonia (1)
- Intervention (1)
- Intervention development (1)
- Interventional Trials (1)
- Interventional cardiology (1)
- Interventional oncological treatment (1)
- Intervertebral disc degeneration (1)
- Intervertebral disc displacement (1)
- Interview (1)
- Interviews (1)
- Intestinal failure-associated liver disease (1)
- Intestinal fistula (1)
- Intestinal metaplasia (1)
- Intestinal neoplasms (1)
- Intimal-medial thickness (1)
- Intolerance (1)
- Intra-abdominal infection (1)
- Intracellular pathogens (1)
- Intracerebral haemorrhage (1)
- Intracranial embolism (1)
- Intracranial haemorrhage (1)
- Intracranial hemorrhage (1)
- Intragastric balloon (1)
- Intraoperative blood salvage (1)
- Intraoperative procedure (1)
- Intraoperative test (1)
- Intraoral scanners (1)
- Intraosseous access (1)
- Intratumoral (1)
- Intratympanic drug delivery (1)
- Intravenous Drug User (1)
- Intravenous antibiotic therapy (1)
- Intravenous injections (1)
- Intravenous iron (1)
- Intrinsic Disorder (1)
- Intrinsic resistance (1)
- Intubation (1)
- Invasive candidiasis (1)
- Invasive fungal infection (1)
- Invasive fungal infections (1)
- Ionization State (1)
- Ipilimumab (1)
- Ireb2 (1)
- Ireland (1)
- Iron Overload (1)
- Iron chelation (1)
- Irregular vaccination (1)
- Ischemia-reperfusion injury (1)
- Ischemia–reperfusion injury (1)
- Isocitrate dehydrogenase (1)
- Isoflurane (1)
- Isoforms (1)
- Isoproterenol (1)
- Isothermal amplification (1)
- Isotope labeling (1)
- Issue 96 (1)
- Italy (1)
- Itpr1 (1)
- Ivor Lewis esophagectomy (1)
- Ixodes (1)
- JAK inhibition (1)
- JAK2V617F (1)
- JNK (1)
- JNK3 (1)
- Jak2(V617F) (1)
- Jaw surgery (1)
- JawsII (1)
- Joint actions (1)
- Joint destruction (1)
- Joubert syndrome (1)
- Jumping (1)
- Jurkat (1)
- Juvenile myoclonic epilepsy (1)
- K-homology RNA-binding domain (1)
- K3EDTA plasma sampling (1)
- KAP (1)
- KCCQ (1)
- KCGS (1)
- KCNH2 (1)
- KCNJ2 mutation (1)
- KCNQ1 (1)
- KCNQ4 (1)
- KDIGO (1)
- KIF (1)
- KIF11 (1)
- KIR (1)
- KLHL11 (1)
- KLK5 (1)
- KOOS IV (1)
- KPS (1)
- KRAS (1)
- Kaisidis plate (1)
- Kallikrein inhibitor (1)
- Kappa (1)
- Karyotypes (1)
- Katherine (1)
- Kava (1)
- Kava hepatotoxicity (1)
- Keap1-Nrf2 (1)
- Keratinocytes (1)
- Ketogenic Diet (1)
- Ki-67/MIB1 (1)
- Ki67 transgenic c‐myc/TGFα mice (1)
- Kidney Transplantation (1)
- Kidney disease (1)
- Kidney diseases (1)
- Kidney neoplasm (1)
- Kidney transplant recipients (1)
- Kidneys (1)
- Kim-1 (1)
- Kinases (1)
- Kinder (1)
- Kindes- und Jugendalter (1)
- Kindheit (1)
- Kinematic posture analysis (1)
- Kinematics (1)
- Kinetochore (1)
- Knee joint sound (1)
- Knee osteoarthritis (1)
- Knee surgery (1)
- Knockout (1)
- Kolorektales Karzinom (1)
- Komorbidität (1)
- Kongress <Wandlitz, 1997> (1)
- Kontrazeption (1)
- Krait (1)
- Krankenversicherung (1)
- Krankheit (1)
- Krebsforschung (1)
- Kupffer cells (1)
- Kurzzeitgedächtnis (1)
- Kutner, Luis (1)
- Kynurenine (1)
- Körpermodifizierung (1)
- L1 cell-adhesion molecule (L1-CAM) (1)
- L1-norm SVM (1)
- LABAs (1)
- LAMP3 (1)
- LAMTOR1 (1)
- LAMTOR2 (1)
- LARS2 (1)
- LASS (1)
- LAT (1)
- LC-MS-Based Clinical Research (1)
- LC-MS-based lipid mediator analysis (1)
- LC-NE system (1)
- LC3 I/II (1)
- LC3B (1)
- LCD-Array (1)
- LCH (1)
- LC–MS/MS (1)
- LDHB (1)
- LDL (1)
- LDL-cholesterol (1)
- LEOSS (1)
- LFA-1 (1)
- LFP (1)
- LHRH receptor (1)
- LIR interaction, (1)
- LIVIN (1)
- LM11A 31 (1)
- LN229 (1)
- LNS (1)
- LOS (1)
- LPP (1)
- LQTS (1)
- LRBA (1)
- LSD1 (1)
- LSEC (1)
- LTB4 (1)
- LTBI (1)
- LUBAC (1)
- LUT (1)
- Label-free (1)
- Laboratory techniques and procedures (1)
- Laborpersonal (1)
- Lack of immunity (1)
- Lactate Dehydrogenase (1)
- Lactation (1)
- Lactic acidosis (1)
- Lactobacillus (1)
- Lafora disease (1)
- Laminin (1)
- Lamivudine (1)
- LanCL2 (1)
- Landmark (1)
- Language delay (1)
- Laparoscopic fundoplication (1)
- Laparostomy (1)
- Laparotomy. Joel-Cohen (1)
- Large vessel occlusion (1)
- Laryngeal Tube (1)
- Laser interstitial thermal therapy (1)
- Laser navigation system (1)
- Lasers (1)
- Late Gadolinium Enhancement (LGE) (1)
- Late gadolinium enhancement (1)
- Late presentation (1)
- Latent transforming growth factor β-binding protein 4 (1)
- Lateral flow antigen testing (1)
- Lateral flow immunoassay (1)
- Lateral recess stenosis (1)
- Laterality (1)
- Le carcinome épidermoïde oral (1)
- Leadership (1)
- Learning algorithms (1)
- Learning outcomes (1)
- Lebensbedingungen (1)
- Leber congenital amaurosis (1)
- Lectin affinity plasmapheresis (1)
- Lecture (1)
- Lee type, functional outcome (1)
- Lee-type (1)
- Leflunomide (1)
- Left Ventricular Mass (1)
- Left atrial appendage closure (1)
- Left ventricular assist device (1)
- Left ventricular function (1)
- Left ventricular mass (1)
- Left ventricular non-compaction, (1)
- Leg alignment (1)
- Legal medicine (1)
- Legionella pneumophila (1)
- Leigh syndrome (1)
- Leishmaniasis (1)
- Lemperle (1)
- Lenalidomide (1)
- Length of stay (1)
- Lennox-Gastaut syndrome (1)
- Lentiviral vectors (1)
- Les macrophages associés aux tumeurs (1)
- Lesion (1)
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive (1)
- Leukocyte depletion filter (1)
- Leukocyte elastase (1)
- Leukocytes (1)
- Leukodystrophy (1)
- Leukotriene (1)
- Lice (1)
- Lifestyle (1)
- Ligand post-insertion (1)
- Light sheet fluorescence microscopy (1)
- Lineage (1)
- Lineage tracing (1)
- Linkage (1)
- Lipedema (1)
- Lipid Transition Temperature (1)
- Lipid metabolism (1)
- Lipid peroxidation (1)
- Lipid signaling (1)
- Lipid solution (1)
- Lipid trafficking (1)
- Lipidol (1)
- Lipiodol (1)
- Lipodystrophy (1)
- Lipopolysaccharide-binding protein (1)
- Liposuction (1)
- Liquid filled MicroLion ion chamber array (1)
- Liquor cerebrospinalis (1)
- Lithium (1)
- Liver Fibrosis (1)
- Liver biopsy (1)
- Liver enzymes (1)
- Liver histology (1)
- Liver metastases (1)
- Liver resection (1)
- Liver transplant (1)
- Liver-Related Complications (1)
- Liver-related complications (1)
- LiverTox (1)
- LncRNA - long noncoding RNA (1)
- Loa loa (1)
- Local IgE (1)
- Local allergic rhinitis (1)
- Local control (1)
- Local field potential (1)
- Localized prostate cancer (1)
- Locally advanced (1)
- Lockdown (1)
- Loco-regional control (1)
- Locomotor circuit (1)
- Lokalrezidiv (1)
- Lomentospora prolificans (1)
- Long QT syndrome (1)
- Long interspersed nuclear elements (LINE) (1)
- Long non-coding RNA (1)
- Long noncoding RNA (1)
- Long term output (1)
- Long term result (1)
- Long-COVID (1)
- Long-term (1)
- Long-term care (1)
- Long-term continence (1)
- Long-term follow up (1)
- Long-term follow-up (1)
- Long-term results (1)
- Long-term-measurements (1)
- Longchain polyunsaturated fatty acids (1)
- Longitudinal analysis (1)
- Low birth weight infant (1)
- Low grade glioma (1)
- Low volume prep (1)
- Low-dose X-irradiation (1)
- Low-dose ionizing radiation (1)
- Low-dose radiation therapy (1)
- Low-grade glioma (1)
- Lower back pain (1)
- Lpar2 (1)
- Ltbp-4 (1)
- Ltbp-4L (1)
- Ltbp-4S (1)
- Ltbp4 (1)
- Lucigenin (1)
- Luftverkehr (1)
- Lumbar Disk Degeneration (1)
- Lumbar spinal canal stenosis (1)
- Lumbar stenosis (1)
- Lumican (1)
- Lung (1)
- Lung Cancer (1)
- Lung adenocarcinoma (1)
- Lung development (1)
- Lung function (1)
- Lung neoplasms (1)
- Lung ultrasound (1)
- Lyme Borreliosis (1)
- Lyme Disease (1)
- Lyme disease - Borreliosis (1)
- Lyme-Borreliose (1)
- Lymph node (1)
- Lymphadenopathy (1)
- Lymphangiectasia (1)
- Lymphangiogenesis (1)
- Lymphangioleiomyomatosis (1)
- Lymphedema (1)
- Lymphocyte (1)
- Lymphocyte subpopulations (1)
- Lymphoepithelioma (1)
- Lymphoid Neoplasia (1)
- Lymphoid tissues (1)
- Lymphom (1)
- Lymphoma Cells (1)
- Lymphomas (1)
- Lymphopenia Mortality (1)
- Lysosomal storage disease (1)
- M. Intracellulare (1)
- M. avium (1)
- M. avium complex (1)
- M. chimaera (1)
- M2-PK (1)
- MACE (1)
- MAGGIC score (1)
- MAIT cell (1)
- MAP Kinases (MAPKs) (1)
- MAP kinase (1)
- MCP (1)
- MCP-1 (1)
- MDD (1)
- MDM2 (1)
- MDR1 (1)
- MEDIC (1)
- MEIS (1)
- MEIS homeodomain protein (1)
- MEIS2 (1)
- MEK inhibitor (1)
- MELD (1)
- MEN1 (1)
- MET (1)
- MGMT (1)
- MGMT promoter (1)
- MID task (1)
- MK-0457 (1)
- MKP1 (1)
- ML-IAP (1)
- MLC tracking (1)
- MLL-rearranged leukemia (1)
- MLN8237 (1)
- MLV (1)
- MM-121 (1)
- MMF (1)
- MMP14 (1)
- MMP2 (1)
- MMPs (1)
- MN1 (1)
- MOLLI (1)
- MPA (1)
- MPM (1)
- MPN (1)
- MPN-U (1)
- MR-based histology (1)
- MR-proADM (1)
- MR-spectroscopy (1)
- MRI patterns of gliomas (1)
- MRI-negative epilepsy (1)
- MRP4 (1)
- MRT (1)
- MS (1)
- MSC-subsets (1)
- MSM (1)
- MT: Non-coding RNAs (1)
- MTCL (1)
- MTHFR-Mutation (1)
- MTHFR-mutation (1)
- MTOR inhibitor (1)
- MTRNR1 (1)
- MTRasym (1)
- MTT (1)
- MUTARS® RS Cup System (1)
- MUTARS® RS cup system (1)
- MVPA (1)
- MYCBP2 (1)
- MYCN amplification (1)
- Machine Learning (1)
- Machine learning algorithms (1)
- Machine teaching (1)
- Macrophage (1)
- Macrophage Transdifferentiation (1)
- Macular neovascularization (1)
- Magnet dislocation (1)
- Magnetencephalography (1)
- Magnetic resonance Imaging (1)
- Magnetic resonance imaging (MRI) (1)
- Magnetoencephalographie (1)
- Magnetoencephalography (1)
- Maintenance therapy (1)
- Maintenance treatment (1)
- Major Depressive Disorder (1)
- Major bleeding (1)
- Major infection after cardiac surgery (1)
- Makrophage (1)
- Makrophagen (1)
- Malariae (1)
- Malate Dehydrogenases (1)
- Male (1)
- Male Population (1)
- Malignancy (1)
- Malignant meningioma (1)
- Malnutrition (1)
- Mamma (1)
- MammaPrint (1)
- Mammalian target of rapamycin (1)
- Mammaplasty (1)
- Mammary gland (1)
- Management (1)
- Manatee invariant (1)
- Manchester scar scale (1)
- Mandatory Vaccinations (1)
- Mandible (1)
- Mandibular gland (1)
- Mandibular gland proteomics (1)
- Mania (1)
- Manner of death (1)
- Manufacturing (1)
- Maple bark disease (1)
- Maple bark strippers’ lung (1)
- Mapping (1)
- Marginal grafts (1)
- Marginal integrity (1)
- Marker genes (1)
- Markov model (1)
- Masking effect (1)
- Mass disaster (1)
- Massenkatastrophe (1)
- Massive Online Open Course (1)
- Mastectomy (1)
- Mastoiditis (1)
- Matching-adjusted indirect comparison (MAIC) (1)
- Materials science (1)
- Maternal morbidity (1)
- Maternal separation (1)
- Mathematical biosciences (1)
- Mathematical functions (1)
- Mathematical methods (1)
- Mathematical model (1)
- Mathematical models (1)
- Maxillofacial reconstruction (1)
- Maxillofacial surgery (1)
- Maxillofacial trauma (1)
- Mcl-1 (1)
- MdM2 (1)
- Mean erythrocyte volume (1)
- Measles (1)
- Measurement equipment (1)
- Mechanical ankle instability (1)
- Mechanical ventilation (1)
- Meckel’s diverticulum (1)
- Median nerve (1)
- Medical (1)
- Medical Oncology (1)
- Medical Physics: Diagnostic (1)
- Medical communication (1)
- Medical ethics (1)
- Medical history (1)
- Medical hypoxia (1)
- Medical imaging (1)
- Medical implants (1)
- Medical management (1)
- Medical school (1)
- Medical staff (1)
- Medical student (1)
- Medical study (1)
- Medical traineeship (1)
- Medication changes (1)
- Medicine and health sciences (1)
- Meersseman test (1)
- Membrane Attack Complex (1)
- Membrane Trafficking (1)
- Membrane assays (1)
- Membrane staining (1)
- Membrane-Phloretin Interaction (1)
- Mena/VASP (1)
- Meningioma (1)
- Mental disorder (1)
- Mental health disorders (1)
- Mental health problems (1)
- Mental health therapies (1)
- Menthol (1)
- Mesangial cells (1)
- Mesenchymal stem cell (1)
- Mesenchymal stem/stromal cells (1)
- Mesenchymal stromal cells (1)
- Mesenchymal stromal cells (MSC) (1)
- Mesh repair (1)
- Metaanalysis (1)
- Metabolic (1)
- Metabolic dysfunction (1)
- Metabolic labeling (1)
- Metabolic models (1)
- Metabolic vulnerabilities (1)
- Metabolism, Inborn Errors (1)
- Metabolomic profile (1)
- Metacognition (1)
- Metal clip (1)
- Metalloproteases (1)
- Metalloproteinases (1)
- Metastasis-directed therapy (1)
- Metastatic renal cell carcinoma (1)
- Metastatic tumors (1)
- Metformin (1)
- Methacholine challenge test (1)
- Methanol (1)
- Methicillin resistance (1)
- Methionine (1)
- Method validation (1)
- Methods (1)
- Methotrexate (1)
- Methylation (1)
- Methylmercury Containing Inactivator (1)
- Methylphenidate (1)
- Mexican alligator lizards (1)
- Mgm1p (1)
- MiR-29 (1)
- MiSpEx Network (1)
- MiSpEx-network (1)
- Mice (1)
- Michael acceptor (1)
- Micro RNAs (1)
- Micro computed tomography (1)
- Micro-CT (1)
- MicroRNA-181a (1)
- MicroRNAs (miRNAs) (1)
- Microalgae (1)
- Microarray (1)
- Microbial mutation (1)
- Microbiology and Infectious Disease (1)
- Microbiology, Virology & Host Pathogen Interaction (1)
- Microenvironment (1)
- Microfilaremia (1)
- Microfluidics (1)
- Microgap (1)
- Microglial cells (1)
- Micrognathia (1)
- Microparticles (1)
- Microphones (1)
- Microphysiological models (1)
- Microplastic (1)
- Microsatellite instability (1)
- Microstates (1)
- Microstructural impairment (1)
- Microtubule (1)
- Mid-intestinal bleeding (1)
- Midbrain/brainstem expression changes (1)
- Middle East respiratory syndrome coronavirus (1)
- Midkine (1)
- Midline laparotomy (1)
- Midwifery (1)
- Migrant health (1)
- Mild chronic inflammation (1)
- Mild cognitive impairment (1)
- Mild hypoxia (1)
- Mindfulness (1)
- Mineralization (1)
- Mini-monovision (1)
- Minimal core of imaging (1)
- Minimal invasive (1)
- Minimal invasive dentistry (1)
- Minimally invasive surgical procedures (1)
- Minimally invasive transforaminal interbody fusion (1)
- Mislocalised proteins (1)
- Mitochondrial Apoptosis (1)
- Mitochondrial Metabolism (1)
- Mitochondrial Permeability Transition (1)
- Mitochondrial Transport (1)
- Mitochondrial amino acid tRNA synthetases (1)
- Mitochondrial disease (1)
- Mitochondrial disorder (1)
- Mitochondrial function (1)
- Mitochondrial proteins (1)
- Mitochondrial respiration (1)
- Mitochondrial shuttles (1)
- Mitomycin C (1)
- Mitoxantrone (1)
- Mixed Lipid Phases (1)
- Mixed hearing loss (1)
- Mmp12 (1)
- Model Organism (1)
- Model organisms (1)
- Moderating factors (1)
- Modified FDI criteria (1)
- Molar tooth sign (1)
- Mole-rat (1)
- Molecular Biology (1)
- Molecular Chaperone (1)
- Molecular diagnosis (1)
- Molecular diagnostic testing (1)
- Molecular diagnostics (1)
- Molecular genetics (1)
- Molecular glue (1)
- Molecular imaging (1)
- Molecular marker (1)
- Molecular matched therapy (1)
- Molecular mimicry (1)
- Molecular signatures (1)
- Molecular subtype (1)
- Molecular therapy (1)
- Molecularly targeted therapy (1)
- Monacolin K (1)
- Monetary incentive delay (1)
- Mongolian spot (1)
- Monoacylglycerol lipase (1)
- Monoclonal antibodies (1)
- Monoclonal antibody (mAb) (1)
- Monocyte gene expression (1)
- Monocytes and macrophages (1)
- Monolithic crown (1)
- Monosaccharide Transport Proteins (1)
- Monte Carlo method (1)
- Monte Carlo simulation (1)
- Mood (1)
- Morphological modeling (1)
- Morphologie (1)
- Mosquito (1)
- Mosquito crop (1)
- Mosquito-plant interaction (1)
- Motility (1)
- Motility disorder (1)
- Motivating factor (1)
- Motivation (1)
- Motor neuron disease (1)
- Motor skills (1)
- Motor-cognitive (1)
- Mouse model (1)
- Moviprep (1)
- Mu-opioid receptor (1)
- Mucomaix® matrix (1)
- Mucopolysaccharidoses (1)
- Multi-Omics (1)
- Multi-center (1)
- Multi-modal feedback (1)
- Multi-motive grid (1)
- Multi-nucleated cardiomyocytes (1)
- Multi-resistant pathogens (1)
- Multi-stakeholder approach (1)
- Multi-syndrome classification (1)
- Multidetector Computed Tomography (1)
- Multidisciplinary management (1)
- Multidrug-resistance (1)
- Multidrug-resistant bacteria (1)
- Multidrug-resistant organisms (1)
- Multidrug-resistant tuberculosis (1)
- Multilevel two-part modelling (1)
- Multiligament instability (1)
- Multimedication (1)
- Multimodal Modeling (1)
- Multimodal imaging (1)
- Multimorbid patients (1)
- Multinomial logistic regression (1)
- Multinucleated giant cells (1)
- Multiomics (1)
- Multiparametric MRI (1)
- Multiplate (1)
- Multiple Sclerosis (1)
- Multiple Transport Systems (1)
- Multiple myeloma (1)
- Multiple trauma (1)
- Multiple-indication review (1)
- Multiplex immunoassay (1)
- Multisensory (1)
- Multiset independent component analysis (1)
- Muscarinic acetylcholine receptor (1)
- Muscle (1)
- Muscle analysis (1)
- Muscle atrophy (1)
- Muscle damage (1)
- Muscle pain (1)
- Muscle tissue (1)
- Muscular diseases (1)
- Musculoskeletal (1)
- Musculoskeletal abnormalities (1)
- Musculoskeletal diseases (1)
- Musculoskeletal mechanics (1)
- Musculoskeletal problems (1)
- Musculoskeletal ultrasound (1)
- Music (1)
- Music chair concepts (1)
- Musical rhythm (1)
- Musician (1)
- Musician-specific seating position (1)
- Mutation databases (1)
- Mycobacteria (1)
- Mycobacterium avium complex (1)
- Mycoses (1)
- Myelin or myeloarchitecture (1)
- Myelodysplastic syndrome (1)
- Myelofibrosis (1)
- Myeloperoxidase (1)
- Myeloproliferative disease (1)
- Myiasis (1)
- Myocardial infarction (MI) (1)
- Myocardial injury (1)
- Myocardial remodeling (1)
- Myocardial revascularization (1)
- Myocardial segmentation (1)
- Myonecrosis (1)
- Myopia (1)
- Myotonic dystrophy (1)
- Mφs (1)
- N-Acetylaspartate (1)
- N-acetyl-L-cysteine (1)
- N-acetylcysteine (1)
- N-cadherin (1)
- N-cadhérine (1)
- N-glycosylation (1)
- N-hydroxysuccinimide (1)
- N-methyl-D-aspartate receptor (1)
- N-myc (1)
- N2 (1)
- N471D strumpellin knock-in mice (1)
- N501Y (1)
- NAD + Analogues (1)
- NAD+-Analogs (1)
- NADP+ Analogues (1)
- NADPH oxidase 4 (1)
- NAD⊕-Isomer (1)
- NAFL (1)
- NCAM (1)
- NCH93 (1)
- NCOA4 (1)
- NDBI (1)
- NDNF interneurons (1)
- NDR1 (1)
- NDUFA6 (1)
- NDUFAF8 (1)
- NEAT1 (1)
- NEAT2 (1)
- NET (1)
- NETs (1)
- NF-kB (1)
- NF-ĸB (1)
- NF-кB (1)
- NFAT (1)
- NFkB (1)
- NGS (1)
- NGS sequencing (1)
- NHE (1)
- NHEJ (1)
- NIS (1)
- NK Receptor (1)
- NK cell subset (1)
- NK cell subsets (1)
- NK receptors (1)
- NKG2A blocking (1)
- NKT cell (1)
- NLPHL (1)
- NLRP3 inflammasomes (1)
- NMDA IgA/IgM antibodies (1)
- NMDA antibody (1)
- NMDAR subunit GluN2B (1)
- NMO-IgG (1)
- NOD2 (1)
- NOS-I (1)
- NOS1AP (1)
- NOXA (1)
- NPC disease (1)
- NPH insulin (1)
- NPSR1 (1)
- NR4A2 (1)
- NR4A3 (1)
- NRAS (1)
- NS1608 (1)
- NS3 protease inhibitor (1)
- NS3-4A protease inhibitor (1)
- NS3/4A protease inhibitors (PI) (1)
- NS5A inhibitors (1)
- NS5B polymerase inhibitor (1)
- NSAIDs (1)
- NSBB (1)
- NSC350625 (1)
- NSE (1)
- NSF (1)
- NSG mice (1)
- NSTEMI (1)
- NTDs (1)
- NTM (1)
- NURF (1)
- NVBP (1)
- NXF1 (1)
- Nachsorge (1)
- Nachweisverfahren (1)
- Nadelstichverletzungen (1)
- NanoBone (1)
- Nanocrystalline (1)
- Nanoparticles (1)
- Nanoplastic (1)
- Nanopore (1)
- National catalogue of competence-based learning objectives in dentistry (1)
- Native T1 (1)
- Native T1 mapping (1)
- Natriuretic peptide (1)
- Natural Killer (NK) Cell (1)
- Natural killer cells (1)
- Nav channel activity (1)
- Nav1.7 (1)
- Nd:YAG laser capsulotomy (1)
- Necroptosis (1)
- Necrosis (1)
- Necrosis (Necrotic Death) (1)
- Necrotic area (1)
- Necrotizing fasciitis (1)
- Needs Assessment [MeSH] (1)
- Needs assessment [MeSH] (1)
- Negative appendectomy rate (1)
- Negative staining (1)
- Neglected tropical diseases (1)
- Negligence (1)
- Nek1 (1)
- Neoadjuvant radiochemotherapy (1)
- Neoadjuvant systemic therapy (1)
- Neoadjuvant therapy (1)
- Neoadjuvant treatment (1)
- Neonatal (1)
- Neonatal brain damage (1)
- Neonatal intensive care unit (1)
- Neonatal morbidity (1)
- Neonatal outcome (1)
- Neonatal surgery outcome (1)
- Neonatal urea cycle disorders (1)
- Neoplasm staging (1)
- Neosexualitäten (1)
- Nephrons (1)
- Nerves (1)
- Nervous system diseases (1)
- Nesplora Aquarium (1)
- Network Neuroscience (1)
- Network analysis (1)
- Network model (1)
- Neugeborenes (1)
- Neural coding (1)
- Neural function (1)
- Neural goal function (1)
- Neural networks (1)
- Neuro-ophthalmology (1)
- NeuroSAFE (1)
- Neurobiology of disease and regeneration (1)
- Neuroblastoma (1)
- Neurochemistry (1)
- Neurodegenerative diseases (1)
- Neurodegenerative syndromes (1)
- Neurodevelopment (1)
- Neurodevelopmental disorder (1)
- Neurodevelopmental disorders (1)
- Neuroendocrine cancer (1)
- Neuroendocrine tumor (1)
- Neuroepithelial (1)
- Neuroepithelial tumor (1)
- Neurofeedback (1)
- Neurofilament light chain (1)
- Neurogenesis (1)
- Neuroligins (1)
- Neuromuscular exercise (1)
- Neuromyelitis optica (1)
- Neuronal dendrites (1)
- Neuronal homeostasis (1)
- Neuronal networks (1)
- Neuronal nitric oxide synthase (1)
- Neuronal plasticity (1)
- Neurooncology (1)
- Neuropathic pain (1)
- Neurophysiologie (1)
- Neurophysiology (1)
- Neuropilin (1)
- Neuropsychiatric disorders (1)
- Neuropsychological testing (1)
- Neuropsychologie (1)
- Neuropsychology (1)
- Neurosurgery (1)
- Neurovascular damage (1)
- Neurovascular lesion (1)
- Neutrophils (1)
- Nevus of Ito (1)
- Nevus of Ota (1)
- New Developments (1)
- New E3-ligase ligands (1)
- Next generation sequencing (1)
- NfL (1)
- Nfe2l2 (1)
- Niche (1)
- Niche differentiation (1)
- Nicolaides-Baraitser syndrome (1)
- Nimotuzumab (1)
- Nkx2-5 (1)
- Nociception (1)
- Nodular lymphocyte predominant Hodgkin lymphoma (1)
- Non-Hodgkin lymphoma (1)
- Non-RCT (1)
- Non-abusive head trauma (NAHT) (1)
- Non-alcoholic fatty liver disease (1)
- Non-allergic-rhinitis (1)
- Non-aneurysmal (1)
- Non-apoptotic functions (1)
- Non-clear cell renal cell cancer (1)
- Non-coding RNAs (1)
- Non-cylindrical folds (1)
- Non-diffractive EDOF-IOL (1)
- Non-expert MRI (1)
- Non-falciparum (1)
- Non-invasive brain stimulation (1)
- Non-neuronal cholinergic system (1)
- Non-nucleoside polymerase inhibitors (NNI) (1)
- Non-operative (1)
- Non-perimesencephalic (1)
- Non-responder (1)
- Non-small-cell lung cancer (1)
- Non-steroidal anti-inflammatory drugs (1)
- Non-trauma (1)
- Non-tuberculous mycobacteria (1)
- Non-urothelial (1)
- Non-vitamin K antagonist oral anticoagulants (1)
- Nonaerosolizing treatment (1)
- Noncoding RNA (1)
- Noninferiority (1)
- Nonoperative management (1)
- Nonpenetrating (1)
- Nonsteroidal anti-inflammatory drugs (1)
- Nontuberculous mycobacteria (1)
- Nonunion (1)
- Non–small-cell lung cancer (1)
- Noradrenergic (1)
- Nordic questionnaire (1)
- Norepinephrine (1)
- Normative modeling (1)
- Notch (1)
- Notch signaling (1)
- Novel treatment target (1)
- Nox inhibition (1)
- NoxA1 (1)
- Nrf-2 (1)
- Nucleolus (1)
- Nucleophosmin-1 (1)
- Nucleus pulposus cells (1)
- Nukleinsäureamplifikationstest (NAT) (1)
- Null responder (1)
- Number of platelets (1)
- Numerical simulation (1)
- Nurses (1)
- Nutrition risk stratification (1)
- Nymphs (1)
- O-GlcNAcylation (1)
- OA (1)
- OECD performance standards (1)
- OGR1 (1)
- OGTT (1)
- OHIP-G14 (1)
- OHRQoL (1)
- ONC201 (1)
- OPRM1 methylation (1)
- OPS (1)
- OR time (1)
- ORP (1)
- OSA (1)
- OSPE (1)
- OTU domain-containing protein 7B (OTUD7B) (1)
- OXA-23 (1)
- OXA-484 (1)
- OXA-58 (1)
- OXPHOS (1)
- Oberflächenantigen-Mutante (1)
- Object perception (1)
- Object vision (1)
- Objectives (1)
- Observational studies (1)
- Obsessive-compulsive disorder (1)
- Obstetric care (1)
- Obstetrics (1)
- Occlusion (1)
- Occupational Accidents (1)
- Occupational disease (1)
- Occupational exposure (1)
- Occupational medicine (1)
- Oceanic boundlessness (1)
- Ocular findings (1)
- Ocular trauma (1)
- Ocular tuberculosis (1)
- Oesophageal cancer (1)
- Oesophagogastric cancer oxaliplatin (1)
- Off-pump surgery (1)
- Okinawa (1)
- Okinawa diet (1)
- Older adult (1)
- Older adults (1)
- Older patient (1)
- Older patients (1)
- Oldest-old (1)
- Olfactory diagnostics (1)
- Olfactory groove meningioma (1)
- Oligodendroglioma (1)
- Oligometastatic (1)
- Omega lipids (1)
- Omicron variant BA.1 (1)
- Omics (1)
- Omphalocele (1)
- Oncogenes (1)
- Oncologic surgery (1)
- Oncolytic adenovirus (1)
- Oncolytic virus (1)
- Oncotargets (1)
- One health (1)
- One-leg stand (1)
- Online Survey (1)
- Online education (1)
- Online-Magazine (1)
- Opacity (1)
- Open Science (1)
- Open abdomen (1)
- Open pulmonary tuberculosis (1)
- Open source concept (1)
- Operation/Chirurgie (1)
- Ophthalmoplegia (1)
- Opiatrezeptor (1)
- Opinion (1)
- Opioid system (1)
- Oposterior urethral valve (1)
- Oppositional defant disorder (1)
- Oppositional defiant disorder (1)
- Opsoclonus-myoclonus syndrome (1)
- Optic nerve atrophy (1)
- Optical coherence tomography angiography (1)
- Optical lenses (1)
- Oral Health Impact Profile (OHIP) (1)
- Oral and maxillofacial surgery (1)
- Oral and maxillofacial trauma (1)
- Oral food challenge (1)
- Oral immunotherapy (OIT) (1)
- Oral implantology (1)
- Oral therapy (1)
- Orbital fracture (1)
- Organ allocation (1)
- Organ failure (1)
- Organ injury (1)
- Organ motion (1)
- Organ rinse (1)
- Organ shortage (1)
- Organ support (1)
- Organ-confined (1)
- Organoids (1)
- Organs at Risk (1)
- Oroantral communication (1)
- Orphan disease (1)
- Orthodontic tooth movement (1)
- Orthodontist (1)
- Orthopaedics (1)
- Oryctolagus cuniculus (1)
- Oscillating saws (1)
- Osimertinib (1)
- Osmosensing (1)
- OspE (1)
- Ossifying fibroma (1)
- Osteocalcin (1)
- Osteoinduction (1)
- Osteonecrosis (1)
- Osteoporosis diagnosis (1)
- Oswestry Disability Score (1)
- Otorhinolaryngological (1)
- Outcome assessment [MeSH] (1)
- Ovale (1)
- Ovarian cancer treatment (1)
- Ovarian carcinoma (1)
- Over-the-scope clip (1)
- Overall survival (1)
- Overweight (1)
- Overwintering (1)
- Oxa1/YidC/Alb3 Membrane Insertases (1)
- Oxaliplatin (1)
- Oxidative phosphorylation (1)
- Oxidativer Stress (1)
- Oxygen (1)
- Oxygen consumption (1)
- Oxygen extraction fraction (1)
- Oxygen uptake (1)
- Oxygen-derived free radicals (1)
- P-gp (1)
- P1NP (1)
- PAC-1 (1)
- PAD-test (1)
- PAH (1)
- PAI-1 (1)
- PAM (1)
- PAPR (1)
- PAR (1)
- PARK4 (1)
- PARK6 (1)
- PARK7 (1)
- PARP (1)
- PATZ1 (1)
- PAX3/FOXO1 (1)
- PBBM (1)
- PBMC (peripheral blood mononuclear cells) (1)
- PBPK simulation (1)
- PBSC (1)
- PBX (1)
- PBX1 (1)
- PC12 cells (1)
- PC12 neuronal differentiation (1)
- PCA (1)
- PCP (1)
- PCSK9 protein (1)
- PCV (1)
- PD-1 inhibitor (1)
- PD1/ PDL1 (1)
- PDCD4 (1)
- PDD - Assessment - Screening (1)
- PDE inhibition (1)
- PDE‐5‐inhibitor (1)
- PDI (1)
- PDK1 (1)
- PDPK1 (1)
- PD‑L1 (1)
- PEA-15 (1)
- PEGylated PLGA (PLGA-PEG) (1)
- PEI (1)
- PELICAN (1)
- PEM-technology (1)
- PF-06273340 (1)
- PFL (1)
- PFOA (1)
- PFOS (1)
- PGC-1α (1)
- PGE2 (1)
- PHR1 (1)
- PI3K inhibitor (1)
- PI3K/mTor inhibition (1)
- PID prevalence (1)
- PIF pocket (1)
- PKA (1)
- PKCε (1)
- PKD (1)
- PKD/IC (1)
- PLAGL1 (1)
- PLGA (1)
- PLK1 (1)
- PLK1 inhibitors (1)
- PLX4032 (1)
- PLX4720 (1)
- PM (1)
- PMA (1)
- PMF (1)
- PMI (1)
- PMMA (1)
- POCT (1)
- POLG (1)
- POR (1)
- PPAR (1)
- PPAR-γ (1)
- PPARγ (1)
- PPTC7 (1)
- PRF (1)
- PRG-1 (1)
- PRG5 (1)
- PRLTS3 (1)
- PROM (1)
- PROMISE (1)
- PRRT (1)
- PRRT2 (1)
- PRoMPT (1)
- PTCH (1)
- PTCH-1 (1)
- PTDM (1)
- PTEN inducible kinase 1 (1)
- PTK2B (1)
- PTM (1)
- PTSD (1)
- PUMA (1)
- PV (1)
- PV loop (1)
- PWI (1)
- PXA (1)
- PYGL (1)
- PacBio SMRT sequencing (1)
- Paediatric Investigation Plan (1)
- Paediatric cancer (1)
- Paediatric oncology (1)
- Paediatric research (1)
- Paediatric trauma patients (1)
- Paediatrics (1)
- Pain scale MWA (1)
- Pain sensation (1)
- Palacos reaction (1)
- Palliative Care [MeSH] (1)
- Pancreas transplantation (1)
- Pancreatic islet (1)
- Pancreatic neuroendocrine tumor (1)
- Pancreatic surgery (1)
- Pancreatitis (1)
- Pancreatoduodenectomy (1)
- Pandemie (1)
- Panel testing (1)
- Panic disorder (1)
- Papillon-Lefèvre syndrome (1)
- Par-4 (1)
- Paracetamol (1)
- Paracoccus denitrificans (1)
- Parainfluenza (1)
- Paraneoplastic neurological syndromes (1)
- Paraneoplastic syndrome (1)
- Parapneumonic pleural effusion (1)
- Parasympathetic (1)
- Parcellation (1)
- Parent support (1)
- Parkinson diagnosis (1)
- Parkinsons disease (1)
- Particle load reduction (1)
- Particle number size distribution (1)
- Particle size distribution (1)
- Particle toxicity (1)
- Particles (1)
- Particulates (1)
- Patellofemoral Joint (1)
- Pathogen reduction (1)
- Pathogenicity (1)
- Pathogens (1)
- Pathologic changes (1)
- Pathological complete response (1)
- Pathologists (1)
- Pathology Section (1)
- Pathophysiology (1)
- Patient Blood Management (1)
- Patient Outcome Assessment (1)
- Patient Outcome Assessment [MeSH] (1)
- Patient Reported Outcome Measures [MeSH] (1)
- Patient and public Involvement (1)
- Patient care (1)
- Patient care planning (1)
- Patient education (1)
- Patient information (1)
- Patient information materials (1)
- Patient isolation (1)
- Patient knowledge (1)
- Patient outcome assessment (1)
- Patient participation (1)
- Patient perspective (1)
- Patient preferences (1)
- Patient reported outcomes (1)
- Patient satisfaction (1)
- Patient*inneninformation (1)
- Patient-Reported Outcomes Version of the Common Terminology Criteria for Adverse Events (1)
- Patient-centered care (1)
- Patient-centred care (1)
- Patient-reported outcomes (1)
- Patientenverfügung (1)
- Pattern recognition receptors (1)
- Pause (1)
- Pdgfrβ (1)
- Pediatric fracture (1)
- Pediatric neuroimaging (1)
- Pediatric oncology (1)
- Pediatric sarcoma (1)
- Pediatric stem cell transplantation (1)
- Pediatric surgery (1)
- Pediatrics (1)
- Pediatrics [MeSH] (1)
- Peer teaching (1)
- Peer-feedback (1)
- Peer-teaching (1)
- Peg3 (1)
- Pegylated liposomal doxorubicin (1)
- Pelargonium sidoides questionable hepatotoxicity (1)
- Pelvic (1)
- Pentaglobin (1)
- Pentose Pathway (1)
- Peptides and proteins (1)
- Per1−/−-mice (1)
- Perceived stigma (1)
- Percutaneous (1)
- Percutaneous endoscopic gastrostomy (1)
- Percutaneous pinning (1)
- Percutaneous ultrasound (1)
- Performing Artists (1)
- Peri-implant disease (1)
- Pericardial effusion (1)
- Pericarditis (1)
- Perilymph (1)
- Perimesencephalic (1)
- Periodic (1)
- Periodontal disease (1)
- Periodontal diseases (1)
- Periodontal therapy (1)
- Periodontal trauma (1)
- Periodontitis grades B and C (1)
- Peripheral blood smears (1)
- Peripheral vascular disease (1)
- Periprocedural anticoagulation (1)
- Peritoneal macrophages (1)
- Peritumoural oedema (1)
- Peri‑implantitis (1)
- Peroxidase (1)
- Perrault syndrome (1)
- Persistence SARS-CoV-2 antibodies (1)
- Persistent organic pollutants (1)
- Personal medicine (1)
- Personal protective equipment (1)
- Personal stigma (1)
- Personalised medicine (1)
- Personalisierte translationale Therapie (1)
- Personality (1)
- Personality disorder (1)
- Personality inventory (1)
- Personalized Medicine (1)
- Pertussis (1)
- Pessar (1)
- Peutz–Jeghers syndrome (1)
- Pfannenstiel (1)
- Pgrmc1 (1)
- Phakic (1)
- Phalangeal fractures (1)
- Phantom study (1)
- Phantoms (imaging) (1)
- Pharm-fMRI (1)
- Pharmaco-nutrition (1)
- Pharmacodynamic (1)
- Pharmacokinetics (1)
- Pharmacological treatment (1)
- Pharmacometrics (1)
- Pharmacotherapy (1)
- Pharmacovigilance (1)
- Pharmacy setting (1)
- Pharyngeal reflex (1)
- Phase 2 (1)
- Phase 3 (1)
- Phase 3 trial (1)
- Phase I clinical trial (1)
- Phase I trials (1)
- Phase II trial (1)
- Phase rotors (1)
- Phase-IV research (1)
- Phase-reset (1)
- Phenotypic plasticity (1)
- Phenylketonuria (PKU) (1)
- Philadelphia Chromosome (1)
- Philadelphia Chromosome-positive leukemia (1)
- Philadelphia chromosome-positive acute leukemia (1)
- Phlyctenule (1)
- Phospho-soda (1)
- Phospho-tau (1)
- Phosphohydrolases (1)
- Phospholipids (1)
- Photoaffinity Labeling (1)
- Physical and mental health (1)
- Physical comorbidities (1)
- Physical fitness (1)
- Physical self-perception (1)
- Physical therapist (1)
- Physician report (1)
- Physician-assisted suicide (1)
- Physics (1)
- Physiotherapy (1)
- Phytochemicals (1)
- Pierre Robin sequence (1)
- Pill Count (1)
- PillCamColon2 (1)
- Pilocytic astrocytoma (1)
- Pim-1 (1)
- Pinhole IOL (1)
- Pink esthetic score (1)
- Piriform cortex (1)
- Placental growth factor (1)
- Placental organoids (1)
- Planning target volume (1)
- Plasma fibronectin (1)
- Plasma transfusion (1)
- Plasma usage (1)
- Plasmacytoid dendritic cell (1)
- Plasmapheresis (1)
- Plasminogen (1)
- Plastic endoprosthesis (1)
- Plastic pollution (1)
- Plastics (1)
- Platelet (1)
- Platelet dysfunction (1)
- Platelet lysate (1)
- Platelet releasate (1)
- Platzierung (1)
- Play (1)
- Pleasure (1)
- Plectin (1)
- Pleural empyema (1)
- Plk1 (1)
- Plus-end (1)
- Pneumococcal conjugate vaccine (1)
- Point of care (1)
- Point-of-care wound diagnostics (1)
- Polarity index (1)
- Police (1)
- Poliomyelitis (1)
- Polo-like kinase 3 (1)
- Poly-Pore (1)
- PolySUMOylation (1)
- Polygenic risk score (1)
- Polyhexanide (1)
- Polymerase Chain Reaction (PCR) (1)
- Polyposis syndrome (1)
- Polyps (1)
- Polysomnography (1)
- Polyunsaturated fatty acid mediators (1)
- Polyunsaturated fatty acids (1)
- Política de Saúde (1)
- Ponatinib (1)
- Pooling (1)
- Poor solubility (1)
- Population dynamics (1)
- Population-based screening (1)
- Porin regulation (1)
- Portal (1)
- Portugal (1)
- Portuguese population (1)
- Posaconazole serum level (1)
- Position paper (1)
- Positron-emission tomography (1)
- Post mortem examination (1)
- Post mortem interval (1)
- Post surgery pain (1)
- Post treatment (1)
- Post-cesarean (1)
- Post-mortem genetic screening (1)
- Post-offence drinking (1)
- Post-processing (1)
- Post-thaw recovery (1)
- Post-transplant (1)
- Post-traumatic stress disorder (1)
- Posterior Cerebral (1)
- Posterior cruciate ligament (1)
- Postmortem (1)
- Postmortem interval (1)
- Postoperative anatomy (1)
- Postoperative infections (1)
- Postoperative nutritional management (1)
- Posttranslational modification (1)
- Posttraumatische Belastungsstörung (1)
- Postural sway (1)
- Posture (1)
- Potassium channel Kir2.1 (1)
- Potassium iodide (1)
- Powered air-purifying respirator (1)
- Practical training (1)
- Practice (1)
- Practice-based research network (1)
- Praeklampsie (1)
- Pre-economic effects (1)
- Pre-emptive immunotherapy (1)
- Pre-operative radiotherapy (1)
- Pre-treatment drug resistance mutations (1)
- PreS1 deletion (1)
- Precision (1)
- Precision medicine (1)
- Precision oncology (1)
- Preclinical (1)
- Preclinical drug development (1)
- Precompetitive development (1)
- Prediction of locoregional recurrence (1)
- Predictive Modeling (1)
- Predictive medicine (1)
- Predictive model (1)
- Predictive processing (1)
- Predictors (1)
- Prenatal ultrasonographic detection rate (1)
- Preoperative diagnostics (1)
- Preoperative radiochemotherapy (1)
- Prepontine (1)
- Presbyopia (1)
- Pressure distribution (1)
- Pressure measuring plate (1)
- Pressure pain (1)
- Presynaptic vesicles (1)
- Pre‐Ligand Assembly Domain (PLAD) (1)
- Primary Care Health Centre (1)
- Primary breast lymphoma (1)
- Primary health care [MeSH] (1)
- Primary molars (1)
- Primary prophylaxis (1)
- Primary sclerosing cholangitis (1)
- Primärversorgung (1)
- Principal component analysis (1)
- Procedural skills (1)
- Produkte zur Desinfektion (1)
- Professional dance (1)
- Professions (1)
- Proficiency testing (1)
- Profiling Transthiolation Activity (1)
- Profilometry (1)
- Progesteron (1)
- Progesterone (1)
- Prognosefaktoren (1)
- Prognostic biomarker (1)
- Prognostic models (1)
- Programming languages (1)
- Promoters (1)
- Propensity score matching (1)
- Proposal (1)
- Prospective randomized Analysis (1)
- Prostaglandin (1)
- Prostaglandin D2 (1)
- Prostaglandin E2 (1)
- Prostate Cancer (1)
- Prostate cancer cell lines (1)
- Prostate-specific membrane antigen (1)
- Prosthetic rehabilitation (1)
- Protease activity (1)
- Proteasomes (1)
- Protective factors (1)
- Protein (1)
- Protein Domains (1)
- Protein Expression (1)
- Protein Folding (1)
- Protein Kinase Inhibitors (1)
- Protein Motifs (1)
- Protein Structure (1)
- Protein Targeting (1)
- Protein aggregates (1)
- Protein complex (1)
- Protein degradation (1)
- Protein domains (1)
- Protein interactions (1)
- Protein kinase (1)
- Protein purify derivative (1)
- Protein tyrosine modification (1)
- Protein-Lipid Interaction (1)
- Protein-Tyrosin-Kinasen (1)
- Protein-translocation (1)
- Proteinkinase (1)
- Proteins (1)
- Proteomic analysis (1)
- Proteostasis (1)
- Protestantism (1)
- Prothrombin complex concentrate (1)
- Prothrombinmutation (1)
- Protocol (1)
- Proton density (1)
- Prototypes (1)
- Proximal (1)
- Proximal humeral fracture (1)
- Prädiktivfaktoren (1)
- Pseudarthrosis (1)
- Pseudo HE-images (1)
- Pseudophakia (1)
- Pseudoprogression (1)
- Psoriasis vulgaris (1)
- Psoriatic arthritis (1)
- Psychiatric traits (1)
- Psychiatrie (1)
- Psychiatry (1)
- Psycho-oncology (1)
- Psychodynamic psychotherapy (1)
- Psychological stress (1)
- Psychometric evaluation (1)
- Psychometrics (1)
- Psychopathologie (1)
- Psychopathology (1)
- Psychophysics (1)
- Psychosocial (1)
- Pteridine (1)
- Public and occupational health (1)
- Publication (1)
- Publication output (1)
- Pulmonary artery pressure (1)
- Pulmonary disease, chronic obstructive (1)
- Pulmonary edema (1)
- Pulmonary failure (1)
- Pulmonary hypoplasia (1)
- Pulse contour analysis (1)
- Pulse pressure variation (1)
- Pulsed SILAC (1)
- Pulswellengeschwindigkeit (1)
- Pumpkin seeds (1)
- Pupillometry (1)
- Purdue Pegboard (1)
- Pustulosis (1)
- Pyogenic (1)
- Pyogenic spondylodiscitis (1)
- Pyruvate (1)
- Python (1)
- QOL (1)
- QT measurement (1)
- Qb-Test (1)
- QbTest® (1)
- Qualitative Research [MeSH] (1)
- Qualitative research [MeSH] (1)
- Qualitative study (1)
- Quality control (1)
- Quality indicators (1)
- Quality management (1)
- Quality of Health Care [MeSH] (1)
- Quality of health care [MeSH] (1)
- Quality, performance, safety and outcomes (1)
- Quantitative (q)T2 mapping (1)
- Quantitative Imaging (1)
- Quantitative features (1)
- Quantitative magnetic resonance imaging (1)
- Quantitative research (1)
- Quantitative sensory testing (1)
- Quantitative trait (1)
- Quantitative trait loci (1)
- Quantra (1)
- Quarantine (1)
- Quasi-longitudinal study (1)
- Questionnaire - Psychometrics - Diagnostics (1)
- Quinine (1)
- Quinolinate phosphoribosyltransferase (1)
- Quinolinic acid (1)
- Quinolones (1)
- R (1)
- R programming language (1)
- R software (1)
- RAD001 (1)
- RAF (1)
- RARP (1)
- RAS (1)
- RAS pathway (1)
- RBC (1)
- RBC-depletion (1)
- RBFOX1 (1)
- RCC (1)
- RD cells (1)
- REM sleep (1)
- REMS (1)
- RESLES (1)
- RET (1)
- RGAG1 (1)
- RH30 cells (1)
- RIP (1)
- RIP1 (1)
- RIPK1 (1)
- RNA Biology (1)
- RNA chaperone (1)
- RNA extraction (1)
- RNA polymerase (1)
- RNA polymerase inhibitors (1)
- RNA processing (1)
- RNA processing machinery (1)
- RNA sequencing (1)
- RNA stability (1)
- RNA turnover (1)
- RNA virus (1)
- RNA viruses (1)
- RNA, long noncoding (1)
- RNA-binding protein (1)
- RNA-templated DNA repair (1)
- RNA/MicroRNA (1)
- RNAP II (1)
- RNActive (1)
- RNAi (1)
- RNAi and CRISPR screens (1)
- RNAseq analysis (1)
- RND (1)
- ROC analyses (1)
- ROC analysis (1)
- ROC-Analysen (1)
- ROS generation (1)
- ROS/RNS (1)
- RPE65 (1)
- RT-PCR-detection (1)
- RT-qPCR (1)
- RTS (1)
- RUFY (1)
- RUNX1/ETO (1)
- Rab proteins (1)
- Rabbit (1)
- Rac1 (1)
- Race (1)
- Radial artery (1)
- Radiation Oncology (1)
- Radiation exposure (1)
- Radiation induced diarrhoea (1)
- Radiation necrosis (1)
- Radical cystectomy (1)
- Radical nephrectomy (1)
- Radiofrequency (1)
- Radiofrequency ablation (1)
- Radioiodine therapy (1)
- Radioiodine uptake test (1)
- Radiology (1)
- Radiology and imaging (1)
- Radiosurgery (1)
- Radiyal arter (1)
- Ragulator complex (1)
- Ramadan (1)
- Raman spectroscopy (1)
- Ramucirumab (1)
- Ramón y Cajal (1)
- Randomisation (1)
- Randomised controlled trial (1)
- Randomised trial (1)
- Randomized (1)
- Randomized Controlled Trial (1)
- Randomized trial (1)
- RapL (1)
- Rapamycin (1)
- Rapid diagnostic test (1)
- Rapid eye movement sleep behavior disorder (1)
- Rare Diseases (1)
- Rare disease (1)
- Rational use (1)
- Rcf1 (1)
- Re-exploration (1)
- Re-exposure (1)
- Re-injury (1)
- Reactogenicity (1)
- Readmission (1)
- Ready-made mouthguard (1)
- Real world (1)
- Real world study (1)
- Real-time MRI (1)
- Real-time phase contrast (1)
- Real-time polymerase chain reaction (PCR) tests (1)
- Real-world data (1)
- Real-world evidence (1)
- RealTime (1)
- Rearing temperature (1)
- Recall rate (1)
- Receptor physiology (1)
- Receptors/Nuclear (1)
- Reconstructed human epidermis (1)
- Reconstruction (1)
- Rectal neoplasms (1)
- Recurrent episodes (1)
- Red blood cells (1)
- Red yeast rice (1)
- Red-lipped arboreal alligator lizard (1)
- Redox (1)
- Redox dependent epigenetic modifications (1)
- Redox modification (1)
- Redox-sensitive GFP (1)
- Redox-sensitive transcription factor (1)
- Redundancy (1)
- Reference (1)
- Referral (1)
- Refractive changes (1)
- Refractive lense exchange (1)
- Refractory AML (1)
- RegJoint™ (1)
- Regenerative medicine (1)
- Region (1)
- Regret (1)
- Regulatory T cells (1)
- Regulatory agencies. (1)
- Regulatory framework (1)
- Regulatory networks (1)
- Rehabilitation outcome (1)
- Rehabilitationsergebnis (1)
- Rehospitalization (1)
- Reintervention (1)
- Rejection (1)
- Relapse (1)
- Relapse surveillance (1)
- Relapsed ALL (1)
- Relative quantification (1)
- Release of mtDNA and mtRNA (1)
- Remote ischemic conditioning (1)
- Remote monitoring (1)
- Renal cancer (1)
- Renal function (1)
- Renal lesions (1)
- Renal replacement therapy (1)
- Renal vein thrombus (1)
- Repatriation of corpses (1)
- Reperfusion (1)
- Replication study (1)
- Repositioning drugs (1)
- Representative survey (1)
- Reproducibility/stability (1)
- Research data (1)
- Research design (1)
- Research investment (1)
- Research patterns (1)
- Research trends (1)
- Research validity (1)
- Resection (1)
- Reservoir function (1)
- Residential care (1)
- Residual myometrial thickness (1)
- Resilience (1)
- Resin composites (1)
- Resource competition (1)
- Respimat® Soft Mist™ Inhaler (1)
- Respiratory Syncytial Virus (1)
- Respiratory signs and symptoms (1)
- Respiratory syncytial virus (1)
- Respiratory tract diseases (1)
- Response (1)
- Response control (1)
- Response criteria (1)
- Responsibility of healthcare policy (1)
- Resting state (1)
- Restricted posture (1)
- Resuscitation (1)
- Reticulon (1)
- Retina (1)
- Retinal degeneration (1)
- Retinal diseases (1)
- Retinoic acid (1)
- Retro-IDEAL (1)
- Retrospective studies (1)
- Retrospective study (1)
- Return to play (1)
- Return to sports (1)
- Return to work (1)
- Reverse electron transfer (1)
- Reverse transcription polymerase chain reaction (1)
- Review (1)
- Reward anticipation (1)
- Reward system (1)
- Rh Antigens (1)
- Rhabdomyoma (1)
- Rheumatology (1)
- Rho GTPases (1)
- Rho-kinase (1)
- Rho/Rho-kinase (1)
- RhoA (1)
- RhoGTPases (1)
- Ribosomal RNA (1)
- Ribosomal S6 phosphorylation (1)
- Ribosomal translation (1)
- Ribosomes (1)
- Richtlinie (1)
- Ridge preservation (1)
- Riftia pachyptila (1)
- Right hemisphere (1)
- Risikofaktoren (1)
- Risikokommunikation (1)
- Risk communication (1)
- Risk prediction (1)
- Risk reduction (1)
- Risk-stratification (1)
- Robotic Radiosurgery (1)
- Robotic tracking (1)
- Robotic-assisted radical prostatectomy (1)
- Rodents (1)
- Roe deer (1)
- Rolandic Spikes (1)
- Roma women (1)
- Rora (1)
- Roughness (1)
- Round window membrane (1)
- Roussel Uclaf Causality Assess- ment Method (RUCAM) (1)
- Routinely Collected Health Data [MeSH] (1)
- Roux-en-Y gastric bypass (1)
- Rtn3 (1)
- Ruijs-Aalfs syndrome (1)
- Rush (1)
- Rush protocol (1)
- Rush-SIT (1)
- Ruxolitinib (1)
- Ryanodine (1)
- S. cerevisiae (1)
- S100 calcium‑binding protein B (1)
- S100b (1)
- S1P1 receptor (1)
- S1P1–5 (1)
- S1P5 (1)
- S1PR1 (1)
- S1PR4 (1)
- S1PR5 (1)
- S63845 (1)
- SAGE (1)
- SAH (1)
- SAH close (1)
- SAMHD1 knockout mouse (1)
- SAMHD1 phosphorylation (1)
- SAP (1)
- SARS CoV 2 (1)
- SARS-COV-2 (1)
- SARS-CoV (1)
- SARS-CoV-2 Pneumonia (1)
- SARS-CoV-2-specific T cells (1)
- SARS-CoV2 (1)
- SARS-CoV‑2 (1)
- SAVI (1)
- SCA2 (1)
- SCA34 (1)
- SCA38 (1)
- SCD14 (1)
- SCMR (1)
- SCN5A (1)
- SCT (1)
- SDF-1 (1)
- SDH (1)
- SDS (1)
- SEAP (1)
- SEC (1)
- SEC-ICP-DRC-MS (1)
- SEER (1)
- SELEX (1)
- SENP6 (1)
- SERS (1)
- SF-12 (1)
- SGPL1 (1)
- SGPL1 knockout cell line (1)
- SH- (S-S)-Groups (1)
- SH-SY5Y neuroblastoma cells (1)
- SHH (1)
- SIADH (1)
- SIDS (1)
- SILAC (1)
- SIRPalpha (1)
- SKALE score (1)
- SKI II (1)
- SLAM-seq (1)
- SLC20A1 (1)
- SLC6a3 (1)
- SLC7A11 (1)
- SLP-76 (1)
- SLUG (1)
- SMAD (1)
- SMAD signaling (1)
- SMOC1 (1)
- SNORD95 (1)
- SNP (1)
- SOCS (1)
- SOFA (1)
- SPARTAN (1)
- SPG8 (1)
- SPPL3 (1)
- SPRTN (1)
- SPSS (1)
- SR protein (1)
- SR-BI (1)
- SRSF3 (1)
- SRSF7 (1)
- SSTI (1)
- ST2L (1)
- STAMPE2 (1)
- STAT5 (1)
- STDP (1)
- STIR (1)
- SUD (1)
- SUDEP (1)
- SUMO chains (1)
- SUMO1-3 (1)
- SUMOylation (1)
- SUN1 (1)
- SUN2 (1)
- SUV (1)
- SW480 Cell (1)
- SW480 cells (1)
- SWATH (1)
- Saccades (1)
- Saccadometry (1)
- Safety culture (1)
- Safety equipment (1)
- Safety learning (1)
- Safety perspectives (1)
- Salivary gland cancer (1)
- Salivary gland carcinoma (1)
- Salivary gland diseases (1)
- Salmonella choleraesuis (1)
- Salmonella infection (1)
- Salt inducible kinase 2 (SIK2) (1)
- Salvage therapy (1)
- Sampling protocol (1)
- Sandfly (1)
- Sanger Sequencing (1)
- Sapacitabine (1)
- Sarcoidosis (1)
- Sarcomas (1)
- Sarcopenia (1)
- Sarcophagidae (1)
- Satisfaction (1)
- Saudi Arabia (1)
- Scalp defect (1)
- ScanWatch (1)
- Scanner models (1)
- Scedosporium spp. (1)
- Scheduling of radiotherapy (1)
- Schizophrenie (1)
- School support (1)
- Schwangerschaft (1)
- Science structure (1)
- Scientifi c competence (1)
- Scientific community (1)
- Scientific publishing (1)
- Scientometria (1)
- Scientometric analysis (1)
- Scientometrics (1)
- Scientometry (1)
- Sclerostin (1)
- Sclerotic glomeruli (1)
- Screening guidelines (1)
- Screening-ELISA (1)
- Screeningfragebogen (1)
- Scrofulous keratitis (1)
- Seasonal variation (1)
- Seattle heart failure model (1)
- Second donation (1)
- Second stage of labor (1)
- Second-line treatment (1)
- Secondary injury cascades (1)
- Secondary prevention (1)
- Secretion (1)
- Sedation (1)
- Sedatives (1)
- Seizures (1)
- Selection bias (1)
- Selective autophagy (1)
- Selenium (1)
- Selenium administration in gynecologic radiation oncology (1)
- Selenoproteins (1)
- Self-assessment (1)
- Self-efficacy (1)
- Self-esteem (1)
- Self-expandable TAVI (1)
- Self-expandable metal stent (SEMS) (1)
- Self-expandable metal stents (1)
- Self-expandable metal stents complications (1)
- Self-management support (1)
- Self-myofascial release (1)
- Self-report (1)
- Semicontinuous (1)
- Semitendinosus tendon autograft (1)
- Sensorimotor processing (1)
- Sensorimotor training (1)
- Sensory Neuroscience (1)
- Sensory neuron (1)
- Sensory perception (1)
- Sensory systems (1)
- Separation of ADP-Binding Enzymes (1)
- Sepsis-bundle (1)
- Septic shock (1)
- Sequelae (1)
- Sequence (1)
- Sequence alignment (1)
- Sequence motif analysis (1)
- Sequencing (1)
- Sequential (1)
- Seribantumab (1)
- Serine proteases (1)
- Serious injured children (1)
- Seroconverter (1)
- Seroepidemiology (1)
- Serology (1)
- Seroprevalence (1)
- Serotype 3 (1)
- Serum Susceptibility (1)
- Serum biomarker (1)
- Severe Acute Respiratory Syndrome (1)
- Severe bacterial infection (1)
- Severe blood loss (1)
- Severe malaria (1)
- Severity of illness index (1)
- Sexual Dysfunctions (1)
- Sexual child abuse (1)
- Sexual violence (1)
- Sexualmedizin (1)
- Sexuelle Dysfunktionen (1)
- Sexuelle Gewalt (1)
- Sexuelle Revolution (1)
- Sexueller Kindesmissbrauch (1)
- Shannon index (1)
- Shared information (1)
- Sharp injuries (1)
- Sharpin (1)
- Shinisaurus crocodilurus (1)
- Sholl analysis (1)
- Shone’s complex (1)
- Shoulder joint (1)
- Shoulder luxation (1)
- Shunt (1)
- Sickle Cell Disease (1)
- Side effect (1)
- Side effects (1)
- Siderosis (1)
- Signal Recognition Particle (1)
- Signal Transduction (1)
- Signal intensity (1)
- Signal transduction (1)
- Signaling ROS (1)
- Signaling pathway (1)
- Signs and symptoms (1)
- Silicosis (1)
- Silver diamine fluoride (1)
- Silver in situ hybridization (1)
- Simulation and modeling (1)
- Simultaneous (1)
- Single nucleotide polymorphism (1)
- Single positive core biopsy (1)
- Single-Molecule Localization Microscopy (SMLM) (1)
- Single-cell RNA sequencing (1)
- Single-cell RNA-seq (1)
- Single-cell RNA-sequencing (1)
- Single-leg hop for distance (1)
- Single-treatment (1)
- Sistemas de Saúde (1)
- Skeletal health (1)
- Skeletal joints (1)
- Skeletal muscle (1)
- Skeletal muscles (1)
- Skills training (1)
- Skin fibroblast (1)
- Skin irritation test (1)
- Skin manifestation (1)
- Skin morphology (1)
- Skp (1)
- Skull base (1)
- Slc11a2 (1)
- Slc25a37 (1)
- Sleep deprivation (1)
- Slow Cortical Potentials, SCP (1)
- Smac mimetic (1)
- Smac mimetics (1)
- Smad (1)
- Small Leucine-rich Proteoglycan (SLRP) (1)
- Small RNA analysis (1)
- Small aperture IOL (1)
- Small bowel atresia (1)
- Small bowel endoscopy (1)
- Small molecules (1)
- Small vessel disease (1)
- Small- and medium-sized enterprises (1)
- Small-bowel endoscopy (1)
- Small-cell lung cancer (1)
- Smart nebulizer (1)
- Smartwatch (1)
- Smooth muscle (1)
- Smooth muscle cell (1)
- Smooth muscle cells (1)
- Snakebite (1)
- Social Media (1)
- Social Phobia (1)
- Social brain (1)
- Social cognition (1)
- Social communication (1)
- Social decision-making (1)
- Social determinants (1)
- Social differences (1)
- Social information processing (1)
- Social neuroscience (1)
- Social phobia (1)
- Social research (1)
- Social sciences (1)
- Social skills training (1)
- Social support (1)
- Sociocognitive predictors (1)
- Sociodemographic characteristics (1)
- Socioeconomic analysis (1)
- Socioeconomic indices (1)
- Socket healing (1)
- Socket preservation (1)
- Sodium chloride (1)
- Soft tissue healing (1)
- Soft tissue infection (1)
- Soft tissue sarcoma (1)
- Soft-tissue sarcoma (1)
- Software (1)
- Software tool (1)
- Software tools (1)
- Solar insolation (1)
- Solidworks 2015 (1)
- SoloSTAR (1)
- Solomon Island skink (1)
- Soluble epoxide hydrolase (1)
- Somatization (1)
- Sonography (1)
- Source reconstruction (1)
- Soziale Ungleichheit (1)
- Sozialpsychiatrischer Dienst (1)
- Spa water (1)
- Spanish National Health System (1)
- Sparse models (1)
- Spatial Attention (1)
- Species identification (1)
- Speciesidentification (1)
- Specific Synthesis (1)
- Specimen preparation and treatment (1)
- Spectral library (1)
- Spectraldomain OCTA (1)
- Spectrin (1)
- Speech discrimination (1)
- Speech signal processing (1)
- Sphere Formation Assay (1)
- Sphingolipid (1)
- Sphingolipidstoffwechsel (1)
- Sphingosine 1-phosphate (1)
- Sphingosine-1-phosphate (1)
- Sphk1 (1)
- Sphk2 (1)
- Spinal fractures (1)
- Spinal injuries (1)
- Spinal surgery (1)
- Spine Register (1)
- Spine care (1)
- Spine density (1)
- Spine fractures (1)
- Spine infection (1)
- Spinocerebellar ataxia (1)
- Spinocerebellar ataxia type 2 (1)
- Splanchnic Hemodynamics (1)
- Spleen (1)
- Splenic dendritic cell (1)
- Splice variants (1)
- Spondylitis (1)
- Spondyloarthritis (1)
- Spondylodiscitis (1)
- Spondylolisthesis (1)
- Spontaneous bacterial peritonitis (1)
- Sports (1)
- Spot sign (1)
- Sprachverstehen (1)
- Spread of Excitation (1)
- Sputum smear-negative (1)
- StUbL (1)
- Stability (1)
- Stage at presentation (1)
- Stakeholder participation (1)
- Standard dataset (1)
- Standard reference values (1)
- Standard risk (1)
- Standardized operating procedures (1)
- Standards of care (1)
- Standardverfahren (1)
- Staphylococcus aureus (1)
- Starvation (1)
- Static MRI (1)
- Statin (1)
- Stationäre Krankenhausfälle (1)
- Statistical analysis (1)
- Statistical methods (1)
- Stavudine (1)
- Steatosis (1)
- Stem cell dose (1)
- Stem cell enumeration (1)
- Stenosis (1)
- Stenotrophomonas maltophilia (1)
- Stentoplasty (1)
- Sterblichkeit (1)
- Stereotactic ablative body radiotherapy (1)
- Stereotactic radiosurgery (1)
- Steroid (1)
- Sterols (1)
- Stigma (1)
- Stigma scale (1)
- Stimulant (1)
- Stimulation experiments (1)
- Stimulus-secretion coupling (1)
- Sting challenge (1)
- Stoma (1)
- Stoppa approach (1)
- Streptomyces hydrogenans (1)
- Stress and resilience (1)
- Stress resilience (1)
- Stress vulnerability/resilience genes (1)
- Stringed bow player (1)
- Stroke Risk (1)
- Stroke genetics (1)
- Stroke prevention (1)
- Stroke unit (1)
- Stroke volume variation (1)
- Stromal cell (1)
- Structural MRI (1)
- Structural genomics (1)
- Structured reporting (1)
- Structured written feedback (1)
- Strukturwandel der Sexualität (1)
- Students (1)
- Sub-segmentation (1)
- Sub-zero exposure (1)
- Subacute cerebellar degeneration (1)
- Subarachnoid Hemorrhage (1)
- Subcutaneous (1)
- Subependymal giant cell astrocytoma (1)
- Subgroup identification (1)
- Subjective effects (1)
- Subpopulation (1)
- Subregions (1)
- Substances for disinfection (1)
- Subterranean (1)
- Subventricular zone (1)
- Sudden Cardiac Death (SCD) (1)
- Sudden infant death syndrome (1)
- Sugar feeding (1)
- Suicidal behavior (1)
- Suicidal ideation (1)
- Suicidal thoughts (1)
- Suicidality (1)
- Suicide attempt (1)
- Sulfasalazine (1)
- Sulfhydryl Groups (1)
- Sulfhydryl-reactivity (1)
- Sulfur metabolism (1)
- Sulphoraphane (1)
- Sunlight (1)
- Superinfection (1)
- Supplemental parenteral nutrition (1)
- Supplementation (1)
- Support vector machine (1)
- Supportivtherapie (1)
- Supraglottic Airway Devices (1)
- Supraspinatus tendon (1)
- Supratentorial (1)
- Supraventricular arrhythmias (1)
- Surface (1)
- Surgical ICU (1)
- Surgical blood loss (1)
- Surgical education (1)
- Surgical risk (1)
- Surgical site infection (1)
- Surgical site occurrence (1)
- Surgical therapy (1)
- Surrogate endpoint (1)
- Survey (1)
- Surveys (1)
- Survival data (1)
- Suspension (1)
- Sustainable Development (1)
- Sustained attention (1)
- Sustained virologic response (1)
- Sustained virological response (1)
- Sustained virological response (SVR) (1)
- Swallowing (1)
- Sweat osmolality (1)
- Sweat secretion rate (1)
- Swept-source OCTA (1)
- Switzerland (1)
- Sycamore (1)
- Syk Kinase (1)
- Syllables (1)
- Symmetrical blocked occlusion (1)
- Sympathetic (1)
- Sympathetic nervous system (1)
- Sympathicolysis (1)
- Symptome (1)
- Symptoms (1)
- Synapse (1)
- Synapses (1)
- Synaptic dysfunction (1)
- Synaptic organizer (1)
- Synaptopodin (1)
- Synaptosomal preparation (1)
- Syncope (1)
- Syndecan-1 (1)
- Synergy (1)
- Synovial inflammation (1)
- Synthetic (1)
- Synthetic biology (1)
- Syrian hamster (1)
- Systemic inflammatory response (1)
- Systemic lupus erythematosus (1)
- Systemic treatment (1)
- Systems & Computational Biology (1)
- Systems biology (1)
- Systems medicine (1)
- T Cell Biology (1)
- T Cells (1)
- T cell receptor (1)
- T cell receptors (1)
- T cell response (1)
- T cell/histiocyte rich large B cell lymphoma (1)
- T helper 17 cells (1)
- T helper cell differentiation (1)
- T-ALL (1)
- T-DM1 (1)
- T-bet (1)
- T-cell development (1)
- T-cell homeostasis (1)
- T-cell homing (1)
- T-cell niche (1)
- T-cell receptor (TCR) (1)
- T-cell targeting (1)
- T-lymphocytes (1)
- T-tubule system (1)
- T-wave alternans (1)
- T1 (1)
- T1 and T2 mapping (1)
- T1 mapping (1)
- T2 (1)
- T84 colon carcinoma cells (1)
- TALE-homdomain protein (1)
- TAM (1)
- TAMs (1)
- TAPSE (1)
- TAVR (1)
- TAX1BP1 (1)
- TB-therapy (1)
- TBI (1)
- TC stenosis (1)
- TCR signaling cascade (1)
- TDAG8 (1)
- TEER (1)
- TEM (1)
- TEPT (1)
- TEVAR (1)
- TG-186 (1)
- TG-43 (1)
- TGF-beta (1)
- TGF-α (1)
- TGFB-induced factor homeobox 1 (1)
- TGIF (1)
- TGR(mREN2)27 (1)
- THRLBCL (1)
- THV (1)
- TIA-1 (1)
- TIC10 (1)
- TIGAR (1)
- TILs (1)
- TIM23 (1)
- TIMP2 (1)
- TIRADS (1)
- TL AOSIS (1)
- TLR (1)
- TLR2/6 (1)
- TLR4 (1)
- TLR7 (1)
- TLR8 (1)
- TMC435 (1)
- TME (1)
- TMEM126B (1)
- TMS (1)
- TMS-EEG (1)
- TNF (1)
- TNF inhibitors (1)
- TNF-α (1)
- TNFR1 (1)
- TOR inhibitor (1)
- TOR signalling (1)
- TOR1A (1)
- TP53 (1)
- TP53 mutation status (1)
- TP53-induced glycolysis and apoptosis regulator (1)
- TPR (1)
- TRAPP (1)
- TRIM25 (1)
- TRIMs (1)
- TRP Channels (1)
- TRP2 (1)
- TRPM8 (1)
- TRPV4 (1)
- TSC-associated neuropsychiatric disorders (1)
- TSC22D3 (1)
- TSP-4 (1)
- TTFields (1)
- TTW nodules (1)
- TUR-P (1)
- TURP (1)
- TVT (1)
- TWINKLE (1)
- TWNK (1)
- Taekwondoka (1)
- Tagging (1)
- Tailored medicine (1)
- Tailored therapy (1)
- Takotsubo Syndrome (1)
- Tamoxifen (1)
- Tamponade (1)
- Tar (1)
- Targeted delivery (1)
- Targeted sequencing (1)
- Targeted tumor therapy (1)
- Tas2r126 (1)
- Tas2r135 (1)
- Tas2r143 (1)
- Tattoo (1)
- Tau (1)
- Tau acetylation (1)
- Tax effect (1)
- Taxane (1)
- Taxonomy (1)
- Tea (1)
- Technical data (1)
- Technicians (1)
- Technique (1)
- Telomere length (1)
- Telomeres (1)
- Tempo-parietal junction (1)
- Temporal lobe epilepsy (1)
- Temporomandibular joint (1)
- Temporomandibular joint dysfunction (1)
- Temsirolimus (1)
- Tendon incontinence repair (1)
- Tendon transplantation (1)
- Term birth (1)
- Terminal ileitis (1)
- Test assay (1)
- Testing (1)
- Testosterone (1)
- Tet-inducible system (1)
- Tetanus (1)
- Tetrahydrobiopterin (1)
- Texture analysis (1)
- Tfrc (1)
- Tgfβ (1)
- Th1 polarization (1)
- Thalidomide (1)
- Theorie der Sexualität (1)
- Therapeutic adherence (1)
- Therapeutic anticoagulation (1)
- Therapeutic competence (1)
- Therapeutics (1)
- Therapie (1)
- Therapies (1)
- Therapy response (1)
- Thermal spring water (1)
- Thermodilution (1)
- Thermogenesis (1)
- Thermoplasma (1)
- Thermoplasma acidophilum Membranes; Tetraetherlipids (1)
- Thiol redox modification (1)
- Thoracic aortic aneurysm (1)
- Thorax (1)
- Three-dimensional back scan (1)
- Three-dimensional echocardiography (1)
- Thrombophilie (1)
- Thrombose (1)
- Thrombosis/hypercoagulable states (1)
- Thrombotic microangiopathy (1)
- Thromboxane (1)
- Thumb carpometacarpal joint osteoarthritis (1)
- Thymocytes (1)
- Thymus (1)
- Thyroid Cancer Cells (1)
- Thyroid disease (1)
- Tick-Borae (1)
- Tick-Born Diseases (1)
- Tick-Borne diseases (1)
- Tick-borne diseases (1)
- Tick-borne encephalitis (1)
- Ticks (1)
- Time in therapeutic range (TTR) (1)
- Time of death (1)
- Time optimization (1)
- Time series (1)
- Time to treatment failure (1)
- Time trend (1)
- Timing (1)
- Tinnitus (1)
- Tissue expander (1)
- Tissue microarray (1)
- Tissue microarray (TMA) (1)
- Tissue stiffness (1)
- Tissue-specificity (1)
- Tobacco (1)
- Tocilizumab (1)
- Toll-like Receptor (TLR) (1)
- Toll-like receptor (TLR) 6 (1)
- Toll-like receptors (1)
- Toll-like-Rezeptoren (1)
- Toluidine blue (1)
- Tomosynthese (1)
- Tonsil (1)
- Tools and ressources (1)
- Tooth Development (1)
- Tooth segmentation (1)
- Tooth transplantation (1)
- Topoisomerase (1)
- Total colonoscopy (1)
- Total elbow arthroplasty (1)
- Total hip arthroplasty (1)
- Total hip replacement (1)
- Total operating room time (1)
- Touchscreen (1)
- Toxic liver disease (1)
- Toxicology (1)
- Toxins (1)
- Tozasertib (1)
- Tracheal Intubation (1)
- Traditional Chinese Medicine (TCM) (1)
- Traditional Indian Medicine (1)
- Trafficking (1)
- Trail (1)
- Traits of medical students (1)
- Trajectories (1)
- Tranexamic acid (1)
- Transcatheter Aortic Valve Implantation (1)
- Transcatheter based aortic valve implantation (1)
- Transcatheter stage 1 (1)
- Transcranial direct current stimulation (1)
- Transcription factor (1)
- Transcription regulation (1)
- Transcriptional control (1)
- Transcriptional regulatory elements (1)
- Transcriptome (1)
- Transcriptome analysis (1)
- Transcriptome microarray (1)
- Transcriptomics (1)
- Transdifferentiation (1)
- Transduction (1)
- Transesophageal echocardiography (1)
- Transfer learning (1)
- Transfer model (1)
- Transferases (1)
- Transformation (1)
- Transfusion practice (1)
- Transgender (1)
- Transgenic SK-2 mice (1)
- Transgenic mice (1)
- Transient (1)
- Transient elastography (1)
- Transient ischemic attack (1)
- Transition invariant (1)
- Transitional cell carcinoma (1)
- Transitional fractures 3D printing (1)
- Transjugular Intrahepatic Portosystemic Shunt (1)
- Transjugular intrahepatic portosystemic shunt (1)
- Translation (1)
- Translation initiation (1)
- Translation proteomics (1)
- Translational (1)
- Translationsregulation (1)
- Transmembrane communication (1)
- Transplant logistics (1)
- Transplantation (1)
- Transplantation Centers (1)
- Transportation (1)
- Transurethral resection of the prostate (1)
- Trastuzumab (1)
- Trauma centre (1)
- Trauma surgery (1)
- TraumaRegister DGU® (1)
- TraumaRegister DGU® (TR-DGU) (1)
- Traumatic dental injury (1)
- Traumatology (1)
- Travel regulations (1)
- Travel times (1)
- Travellers (1)
- Treatment effectiveness (1)
- Treatment management (1)
- Treatment modification (1)
- Treatment protocol (1)
- Treatment rates (1)
- Treatment response (1)
- Trees (1)
- Triamcinolone acetonide (1)
- Trichuris suis ova (1)
- Trimeric autotransporter adhesins (1)
- Triple negative (1)
- Triple therapy (1)
- Triple-negative breast cancer (1)
- Trisomy 21 (1)
- Trk (1)
- TrkC (1)
- Trousseau’s syndrome (1)
- Trueness (1)
- Truncating mutation (1)
- Truncus arteriosus (1)
- Tuberous sclerosis complex (1)
- Tubers (1)
- Tularemia (1)
- Tumor cell (1)
- Tumor growth (1)
- Tumor heterogeneity (1)
- Tumor infiltrating lymphocytes (1)
- Tumor interstitial fluid pressure (1)
- Tumor obstruction (1)
- Tumor subtype (1)
- Tumor suppressor protein (1)
- Tumor therapy (1)
- Tumor volume (1)
- Tumorsphere Formation (1)
- Tumour biomarkers (1)
- Turkish (1)
- Tween20 (1)
- Twist (1)
- Two-hit hypothesis (1)
- Type 1 diabetes (1)
- Type 2 Diabetes mellitus (1)
- Type three hypersensitivity (1)
- Tyrosine kinase inhibitor (1)
- Tyrosine kinase inhibitor (TKI) (1)
- Tyrosine kinase inhibitor mTOR inhibition (1)
- Tyrosine kinases (1)
- Tyrosinemia (1)
- T‑DM1 (1)
- U-87MG (1)
- UBA domain (1)
- UDP-glucose ceramide glycosyltransferase (1)
- UHPLC-MS (1)
- ULBP4 (1)
- UPPS (1)
- UPR (1)
- USA (1)
- USP28 (1)
- USP32 (1)
- USP9X (1)
- UTUC (1)
- UVA (1)
- UWB diagnostics (1)
- Ubiquitin (1)
- Ubiquitin kinase PINK1 (1)
- Ubiquitin ligase (1)
- Ubiquitin signaling (1)
- Ubiquitin-binding module (1)
- Ulixertinib (1)
- Ultra microscopy (1)
- Ultra-rush protocol (1)
- Ultraschall (1)
- Ultrasonic nebulizer (1)
- Ultrasound imaging (1)
- Umbilical cord (1)
- Uncertainty (1)
- Underfeeding (1)
- Undergraduate (1)
- Undergraduate education (1)
- Undergraduate training (1)
- Undergraduates (1)
- Understanding (1)
- Undiagnosed patients (1)
- Ungleichheit (1)
- Unilateral hip osteoarthritis (1)
- Unique information (1)
- United States (1)
- União Européia (1)
- Upgrading (1)
- Upper airway infection (1)
- Upper respiratory tract infection (1)
- Urachal cancer (1)
- Urachus carcinoma (1)
- Urban (1)
- Ureter (1)
- Urinary continence (1)
- Urinary incontinence (1)
- Urine (1)
- Urologic tumors (1)
- Urological oncology (1)
- Urothelial cancer (1)
- Urothelial carcinoma (1)
- Urothelial cells (1)
- Urticaria (1)
- Usutu virus (1)
- Uterus (1)
- Uveal melanoma (1)
- VARGADO (1)
- VASP (1)
- VBM (1)
- VE-cadherin (1)
- VEGF receptor 2 internalization and signaling (1)
- VEGFA (1)
- VEGFR (1)
- VEGFR-2 (1)
- VEGFR-3 (1)
- VF (1)
- VGAT-ChR2 (1)
- VHH (1)
- VHL (1)
- VIM (1)
- VIP (1)
- VIP1 (1)
- VIS (1)
- VISTA (1)
- VLA4 (1)
- VPA-analogues (1)
- VPAC1 (1)
- VT (1)
- VUS (1)
- VX-2 (1)
- VX680 (1)
- Vaccination breakthrough (1)
- Vaccine breakthrough (1)
- Vacuoles (1)
- Vaginal breech delivery (1)
- Vaginal delivery (1)
- Vagus nerve (1)
- Vagus nerve stimulation (1)
- Value-added effect (1)
- Valvular cardiomyopathy (1)
- Variant of concern (1)
- Variceal bleeding (1)
- Vascular biology (1)
- Vascular cognitive disorder (VCD) – Paranoid hallucinatory syndrome – Late-onset trauma-related symptoms – Depression – Assertive community treatment (ACT) (1)
- Vascular disease (1)
- Vascular emergencies (1)
- Vascular endothelial growth factor A (1)
- Vascular endothelial growth factor receptor 2 (1)
- Vascular permeability (1)
- Vasculogenesis (1)
- Vasospasm (1)
- Vector mosquito (1)
- Vector-borne infections (1)
- Vein (1)
- Veino-lymphatic separation (1)
- Vemurafenib (1)
- Venous Thromboembolism (1)
- Venous thromboembolism (1)
- Venous thrombosis (1)
- Ventilators (1)
- Ventricular arrhythmia (1)
- Ventricular arrhythmias (1)
- Ventricular tachyarrhythmia (1)
- Ventricular tachyarrhythmic event (1)
- Venöse Thrombose/Genetik (1)
- VeroE6‐eGFP cells (1)
- Versorgungsstruktur (1)
- Versorgungsstrukturen (1)
- Vertebral augmentation (1)
- Vertebral body (1)
- Vertebral body stenting (1)
- Vertebral fracture (1)
- Vertigo (1)
- Vespid venom allergy (1)
- Vibroarthrography (1)
- Victimization (1)
- Video rasterstereography (1)
- Video-oculography (1)
- Videolaryngoscopy (1)
- Videorasterstereography (1)
- Vincristine (1)
- VirB (1)
- Viral Load (1)
- Viral core (1)
- Viral hepatitis (1)
- Viral oncology (1)
- Viral replication (1)
- Virchow-Robin Spaces (1)
- Virological Failure (1)
- Virological Response (1)
- Virological failure (1)
- Virological testing (1)
- Virologie (1)
- Virology (1)
- Virotherapy (1)
- Virtual implant planning (1)
- Virtual noncalcium reconstructions (1)
- Virtual patients (1)
- Virulence (1)
- Virus trapping (1)
- Virusisolierung (1)
- Viruslast (1)
- Visual Perception (1)
- Visual impairments (1)
- Visual system (1)
- Visual-field localizer (1)
- Vitamin (1)
- Vitamin K antagonists (1)
- Vitreous opacity (1)
- Vitreous samples (1)
- Voltage attenuation (1)
- Volume overload (1)
- Volume reduction of thyroid nodules (1)
- Volumetric analysis (1)
- Volumetric indexes (1)
- Volunteer donor (1)
- Von Hippel–Landau (1)
- Voriconazole (1)
- Voxel-based morphometry (1)
- WASH complex subunit 5 (1)
- WIPI2 (1)
- WIPI2b (1)
- WNT (1)
- WRNIP1 (1)
- WT1 (1)
- WYE-354 (1)
- Wait and see (1)
- Wakefulness (1)
- Wastewater-based epidemiology (WBE) (1)
- Water chemistry (1)
- Water contamination (1)
- Watertight Dural closure (1)
- Weak bases (1)
- Wearable cardioverter‐defibrillator (1)
- Web 2.0 (1)
- Weight distribution (1)
- Weight loss (1)
- West Nile fever (1)
- West Nile neuroinvasive disease (1)
- West Nile virus (1)
- Western Blotting (1)
- Western blot (1)
- Western diet (1)
- Westphal-Paradigm (1)
- White matter hyperintensity (1)
- Whole genome association (1)
- Whole slide images (1)
- Wilms tumor (1)
- Wilson disease (WD) (1)
- Wing morphometry (1)
- Winter survival (1)
- Withings (1)
- WoMo score (1)
- Women in medicine (1)
- Women in science (1)
- Work shadowing (1)
- Working memory capacity (1)
- Workplace (1)
- Workstation comparison (1)
- Wound healing potential (1)
- Wounds and injuries (1)
- X-ray Crystallography (1)
- X-ray computed (1)
- XCL1/XCR1 axis (1)
- XL probe (1)
- XS52 (1)
- Xenorhabdus (1)
- YB-1 (1)
- YK-4-279 (1)
- YM155 (1)
- YWHAE (1)
- YWHAZ (1)
- Yamane (1)
- Yarrowia lipolytica (1)
- Yarrowia lipolytica mitochondrial genome complex I NADH: ubiquinoneoxidoreductase (1)
- Yeast-2-Hybrid (1)
- Yellow fluorescent protein (1)
- Yoga (1)
- Zeckenübertragene Erkrankungen (1)
- Zentrifugalanalysator (1)
- Zervixverkürzung (1)
- Zika (1)
- Zika Virus (1)
- Zika vaccine (1)
- Zirconia (1)
- Zuckerkandl’s tubercle (1)
- Zwangseinweisungen (1)
- Zymosan-induced peritonitis (1)
- [18F]FET PET (1)
- a disintegrin and metalloprotease 10 (ADAM10) (1)
- aGVHD (1)
- abdominal aortic aneurysm (1)
- abdominal imaging (1)
- abemaciclib (1)
- ablation techniques (1)
- abnormal tumor vasculature (1)
- abscisic acid (1)
- abscopal effect (1)
- abuso (1)
- academic (1)
- academic medicine (1)
- acarboxyprothrombin (1)
- acceptable change limit (1)
- accidental falls [MeSH] (1)
- accidents (1)
- acetabular fracture (1)
- acetylation (1)
- acetylcholine binding protein (1)
- acetylcholine receptors (1)
- acetylcholinesterase (1)
- acetylcholinesterase (AChE) inhibition (1)
- acetylcholinesterase inhibition (1)
- acid dentine lysate (1)
- acid sphingomyelinase (ASMase; Smpd1) (1)
- acne inversa (1)
- acneiform skin toxicity (1)
- acoustic radiation force impulse (1)
- acoustic radiation force impulse imaging (1)
- acquired LQT syndrome (1)
- acquired drug resistance (1)
- acriflavine (1)
- actin cytoskeleton (1)
- actin dynamics (1)
- action (1)
- action sounds (1)
- action-effect association (1)
- activated clotting time measurement (1)
- activated factor XIII (1)
- activation receptors (1)
- active/deactive transition (1)
- activities of daily life (1)
- activity-based benefits (1)
- actography (1)
- acupuncture (1)
- acute and chronic graft versus host disease (a/c GVHD) (1)
- acute attacks (1)
- acute cholecystitis (1)
- acute chronic inflammation (1)
- acute decompensation of cirrhosis (1)
- acute exacerbations of COPD (1)
- acute infections (1)
- acute inflammation (1)
- acute leukemia (1)
- acute liver failure (1)
- acute liver injury (1)
- acute lung injury (ALI) (1)
- acute lymphatic leukemia (1)
- acute lymphoblastic leukaemia (1)
- acute myeloid leukemia (AML) (1)
- acute pain (1)
- acute stroke (1)
- acute stroke care (1)
- acute-on-chronic liver failure (ACLF) (1)
- acute‐on‐chronic liver failure (1)
- adaptation plan (1)
- adaptive cardiac remodelling (1)
- adaptive immune escape (1)
- adaptive immunity (1)
- additive manufacturing (1)
- adeno-associated virus (1)
- adenocarcinoma (1)
- adenomatous polyposis (1)
- adenosine receptors (1)
- adeno‐associated virus (1)
- adiabatic saturation (1)
- adiponectin (1)
- adipose tissue (1)
- adipose tissue-derived stem cell (1)
- adipose-derived mesenchymal stem/stromal cells (1)
- adipose-derived stem cells (1)
- adipose-derived stem cells (ASCs) (1)
- adiposity (1)
- adjustment disorder (1)
- adjuvant radiotherapy (1)
- adolescent (1)
- adolescentes (1)
- adolescents’ health (1)
- adoptive cell therapy (1)
- adoptive immunotherapy (1)
- adrenal insuffciency (1)
- adrenergic therapy (1)
- adrenoceptors (1)
- adult and elderly patients (1)
- adult attention deficit/hyperactivity disorder (adult ADHD) (1)
- adult congenital heart disease (1)
- advance directive (1)
- advanced (1)
- advanced breast cancer (1)
- advanced glycation end products (1)
- advanced melanoma (1)
- adverse effects (1)
- adversity (1)
- aerobic exercise (1)
- aerodynamics (1)
- aerosol (1)
- aesthetics (1)
- affective disorder (1)
- affective disorders (1)
- affinity purification (1)
- affordance (1)
- aftercare structures (1)
- aged [MesH] (1)
- agent-based modeling (1)
- agent-based models (1)
- aggressiveness (1)
- agility (1)
- agonists (1)
- agreeableness (1)
- air abrasive (1)
- air pollution (1)
- air pouch (1)
- airborne bacteria (1)
- airway (1)
- airway remodeling (1)
- alcohol dehydrogenase (ADH) (1)
- alcohol metabolism (1)
- alcoholic fatty liver disease (1)
- alcoholic hepatitis (1)
- alcoholic liver injury (1)
- aligners (1)
- aliphatic halogenated hydrocarbons (1)
- alkaloid (1)
- all-ceramic (1)
- alleles (1)
- allergen immunotherapy (1)
- allergic rhinitis (1)
- allergy (1)
- alloHSCT (1)
- allocation (1)
- allogeneic (1)
- allogeneic donor (1)
- allogeneic hematological stem cell transplantation (1)
- allogeneic hematopoietic stem cell transplantation (aHSCT) (1)
- allogeneic stem cell transplant (1)
- allogeneic transplantation (1)
- allostasis (1)
- allosteric inhibition (1)
- allosteric regulation (1)
- alpelisib (1)
- alpha peak (1)
- alpha receptor (1)
- alpha-fetoprotein (1)
- alpha-galactosidase A deficiency (1)
- alpha7 nicotinic acetylcholine receptor (1)
- alphaSynuclein (1)
- alpharetroviral vector (1)
- alpinia zerumbet (1)
- alteplase (1)
- alternative 3′ end processing (1)
- alternative matrices (1)
- alternative oxidase (1)
- alternative splicing (1)
- alveolar macrophages (1)
- alzheimer disease (1)
- ambiguity (1)
- amblyopia (1)
- ameloblastoma (1)
- amide proton transfer (1)
- amino acid PET (1)
- amisulpride (1)
- amlexanox (1)
- amoeboid (1)
- amoxicillin/metronidazole (1)
- amygdala (1)
- amygdalin (1)
- amyloid beta-peptides (1)
- amyotrophic lateral sclerosis (1)
- anaemia walk-in clinic (1)
- anaesthesia in orthopaedics (1)
- anaesthetics (1)
- anal carcinoma (1)
- analgesia based sedation (1)
- anaphylactic reactions (1)
- anastomotic leakage (1)
- anatomy (1)
- anatomy and histology (1)
- anesthesia (1)
- anesthesiology (1)
- aneurysm (1)
- angio-immunogenic switch (1)
- angioedema control test (1)
- angiokeratoma diffuse (1)
- angioplasty (1)
- angiopoietin-2 (1)
- angiopoietin-like 3 (ANGPTL3) (1)
- angiopoietins (1)
- angiostasis (1)
- animal host (1)
- anisotropy (1)
- annual bleeding rate (1)
- anorectal malformation (1)
- anoxygenic phototrophic sulfur bacteria (1)
- antenatal characteristics (1)
- antenatalne značilnosti (1)
- anterior chamber depth changes (1)
- anti-CD3 antibody (1)
- anti-EGFR therapy (1)
- anti-GD2 immunotherapy (1)
- anti-HBc (1)
- anti-bacterial agents (1)
- anti-cancer therapy (1)
- anti-chronic myeloid leukemia (1)
- anti-citrullinated protein antibodies (1)
- anti-diabetes (1)
- anti-epileptic drug (1)
- anti-idiotypes (1)
- anti-inflammatory (1)
- anti-inflammatory agent (1)
- anti-inflammatory agents (1)
- anti-inflammatory drug (1)
- anti-inflammatory effects (1)
- anti-neural autoantibodies (1)
- anti-retroviral agents (1)
- anti-skin aging (1)
- anti-tumor activity (1)
- antiadhesive composites (1)
- antiangiogenic therapy (1)
- antiangiogenic therapy resistance (1)
- antibacterial composites (1)
- antibacterial therapy (1)
- antibiotic (1)
- antibiotic prophylactic therapy (1)
- antibiotic prophylaxis (1)
- antibiotic treatment (1)
- antibiotics (1)
- antibody (1)
- antibody tests (1)
- anticancer agents (1)
- anticholinergic burden (1)
- anticipation (1)
- anticoagulant (1)
- anticoagulants (1)
- anticonvulsant (1)
- anticonvulsant activity (1)
- antidepressants (1)
- antifibrotic therapy (1)
- antifungal activity (1)
- antifungal agents (1)
- antifungal combination therapy (1)
- antifungal host response (1)
- antifungal management (1)
- antifungal prophylaxis (1)
- antigen (1)
- antigen detection (1)
- antigenic variation (1)
- antigens of infectious origin (1)
- antihelix shaping (1)
- antihormone therapy (1)
- antimicrobial activity (1)
- antimicrobial stewardship (1)
- antioxidant activity (1)
- antioxidant defense (1)
- antiproliferative activity (1)
- antireflux surgery (1)
- antiresorptive agents (1)
- antiseizure (1)
- antisense oligonucleotides (1)
- antisynthetase antibodies (1)
- antisynthetase syndrome (1)
- antitumor immunity (1)
- antiviral agents (1)
- antiviral peptide (1)
- antiviral signaling (1)
- anxiety disorders (1)
- aortic aneurysm (1)
- aortic root replacement (1)
- aortic valve repair (1)
- aortic valve-sparing (1)
- apex (1)
- aphrodisin (1)
- apical constriction (1)
- apical junction (1)
- apical polarity (1)
- apigenin (1)
- apixaban (1)
- apolipoprotein B (1)
- apoptotic cells (1)
- apparent diffusion constant (1)
- apparent motion (1)
- apps (1)
- aprotinin (1)
- aptamer modeling (1)
- aquaporin 1 (1)
- aquaporin-4 (AQP4) antibody (1)
- arachidonate 12/15-lipoxygenase (Alox12/15) (1)
- arachidonate 15-lipoxygenase (1)
- arachidonic acid (AA) (1)
- arbeitsbedingte Infektionen (1)
- archaea (1)
- archaeosomes (1)
- architecture (1)
- arm (1)
- aromatics (1)
- arsenic trioxide (1)
- arterial hypertension (1)
- arterial stiffness (1)
- artery (1)
- artesunate (ART) (1)
- articular cartilage (1)
- articular chondrocytes (1)
- articulatory motor cortex (1)
- artifacts (1)
- artificial feeding (1)
- artificial intelligence (AI) (1)
- artificial neural networks (1)
- aryl hydrocarbon receptor (1)
- asparaginyl endopepdidase (AEP) (1)
- aspiration (1)
- assay development (1)
- assembly (1)
- assembly factor (1)
- associative memory (1)
- asthma phenotypes (1)
- astrocyte (1)
- astrocyte heterogeneity (1)
- astroglia (1)
- asymmetric hearing (1)
- asymptomatic (1)
- asymptomatic temporal encephaloceles (1)
- at-risk mental state (1)
- ataxia (1)
- ataxia score (1)
- athletes (1)
- athletic training (1)
- atomic power (1)
- atopic dermatitis (1)
- atopy (1)
- atrial septostomy (1)
- atrophy (1)
- attachment (1)
- attention deficit hyperactivity disorder (1)
- attention modulation (1)
- attention-deficit/hyperactivity disorder (1)
- attention-deficit/hyperactivity disorder (ADHD) (1)
- attention-deficit/hyperactivitydisorder (1)
- attractiveness (1)
- atypical EGFR mutations (1)
- audition (1)
- auditory (1)
- auditory development (1)
- auditory fMRI (1)
- auditory language processing (1)
- auditory prediction (1)
- augmentation materials (1)
- authentication (1)
- authorship (1)
- autistic disorder (1)
- auto-structure (1)
- autoantigen (1)
- autobiographical memories (1)
- autogenous tooth roots (1)
- autograft (1)
- autoimmune encephalitis (1)
- autoimmune encephalomyelitis (1)
- autoimmune polyglandular syndrome type 2 (1)
- autoimmune thyroiditis (1)
- autoimmune-mediated psychosis (1)
- automated patch-clamp (1)
- automatic environmental tobacco smoke emitter (1)
- automatic handwriting analysis (1)
- automatic scene classification (1)
- autophagic cell death (1)
- autophagy inhibition (1)
- autophagy-dependent cell death (1)
- autopsy (1)
- autoreactivity (1)
- autovaccine (1)
- avelumab (1)
- aviscumine (1)
- awake surgery (1)
- axon (1)
- azacitidine (1)
- azaindole (1)
- azoospermia (1)
- b-cell lymphomas (1)
- back pain (1)
- back scan (1)
- bacteremia (1)
- bacterial leakage (1)
- bacterial translocation (1)
- bacterial viability (1)
- bacteriophages (1)
- bacterium (1)
- baicalein (1)
- balanced state (1)
- ball (1)
- ballet (1)
- balloon pulmonary angioplasty (1)
- bariatric surgery (1)
- baroreflex (1)
- barriers to implementation (1)
- basal cell carcinoma (1)
- basal insulin (1)
- basic leucine zipper transcription factor ATF-like (1)
- basic mechanisms (1)
- basilar artery occlusion (BAO) (1)
- basonuclin 2 (1)
- bats (1)
- beads (1)
- beam quality correction factors (1)
- behavioral adverse events (1)
- behavioral inhibition (1)
- behavioral performance (1)
- behavioural rhythms (1)
- belimumab (1)
- benchmarking (1)
- bendamustine (1)
- benfooxythiamine (1)
- berotralstat (1)
- best medical treatment (1)
- beta band (1)
- beta blockade (1)
- beta-band activity (1)
- beta-blocker (1)
- beta-lactamases (1)
- beta2-adrenoceptor (1)
- betamethasone dipropionate (1)
- beta‐trace protein (1)
- bicuspid aortic valve (1)
- biglycan (1)
- bilateral (1)
- bile (1)
- bile acids (1)
- bile duct stenosis (1)
- biliary cirrhosis (1)
- binary search procedure (1)
- binaural cochlear implants (1)
- binding (1)
- binocular vision (1)
- bio-absorbable mesh (1)
- bioacoustics (1)
- bioactive lipids (1)
- bioactive phospholipids (1)
- bioactive phytochemicals (1)
- bioactivity (1)
- bioavailability (1)
- biobank (1)
- biochanin A (1)
- biochemical recurrence (1)
- biochemical relapse free survival (1)
- biochemistry (1)
- bioequivalence (1)
- bioimaging (1)
- biological maturation (1)
- biological mesh (1)
- biological transport (1)
- biological treatments (1)
- biologically inspired computing (1)
- biologicals (1)
- biologization (1)
- biomarker study (1)
- biomechanics (1)
- biomolecular analysis (1)
- biopsy naïve (1)
- biorelevant dissolution (1)
- biotin deficiency (1)
- bipolar disorders (1)
- birch pollen allergoid (1)
- bistable (1)
- bladder cancer (BCa) (1)
- bladder dose (1)
- bladder exstrophy-epispadias complex (1)
- bladder neck stenosis (1)
- blastic plasmacytoid dendritic cell neoplasm (1)
- bleomycin (1)
- blinatumomab (1)
- blood borne infection (1)
- blood cell mutations (1)
- blood coagulation (1)
- blood coagulation factor XIII (1)
- blood concentrates (1)
- blood consumption (1)
- blood culture (1)
- blood donor (1)
- blood donor screening (1)
- blood flow recovery (1)
- blood hiv rna (1)
- blood loss (1)
- blood safety (1)
- blood-cerebrospinal fluid barrier (1)
- bloodborne viruses (1)
- bloodstream infections (1)
- blow flies (1)
- blow fly (1)
- blutübertragbare Infektionskrankheiten (1)
- bmal1 (1)
- body dysmorphic disorder (1)
- body posture (1)
- body sway (1)
- body weight distribution (1)
- bone augmentation (1)
- bone barrow (1)
- bone chips (1)
- bone damage (1)
- bone loss (1)
- bone marrow (1)
- bone marrow derived mononuclear cells (1)
- bone marrow metastasis (1)
- bone marrow mononuclear cells (1)
- bone morphogenetic protein-2 (1)
- bone morphogenetic proteins (BMPs) (1)
- bone substitute material (1)
- bone substitutes (1)
- bone tissue (1)
- bone tissue engineering (1)
- bone tissue regeneration (1)
- bone-marrow (1)
- bone-regeneration (1)
- bone‐screw (1)
- bone–implant interface (1)
- booster (1)
- borrelia mayonii (1)
- bottom-up (1)
- bowel dysfunction (1)
- bowel management (1)
- brachytherapy imaging methods (1)
- brain (1)
- brain anatomy (1)
- brain disorders (1)
- brain infection (1)
- brain injury (1)
- brain oscillations (1)
- brain phosphorylome (1)
- brain shift (1)
- brain signal complexity (1)
- brain structure (1)
- brainmass (1)
- brainsize (1)
- branched-chain amino acids (BCAA) (1)
- breakpoint cluster region (1)
- breast (1)
- breast cancer diagnosis (1)
- breast cancer systemic therapy (1)
- breast cancer treatment (1)
- breast tumor (1)
- breech (1)
- broad-range qPCR (1)
- broadly neutralizing antibodies (1)
- bromodomain and extraterminal (BET) protein (1)
- bronchial allergen challenge (1)
- bronchial allergen provocation (1)
- bronchial epithelium (1)
- bronchiolitis obliterans syndrome (1)
- bronchodilator (1)
- buccal mucosa (1)
- buccal mucosal graft urethroplasty (1)
- bullying (1)
- bundle (1)
- buparlisib (1)
- burden of disease (1)
- burkholderia (1)
- burkholderia cepacia complex infections (1)
- burns (1)
- butyrylcholinesterase (1)
- bypass (1)
- c-MET (1)
- c-MYC (1)
- c-kit (1)
- c1orf124 (1)
- cBioPortal (1)
- cFLIP (1)
- cGAS-STING (1)
- cHL (1)
- cIAP1 (1)
- cIAP1 BIR (1)
- cIAP1/2 (1)
- cabazitaxel (1)
- cadherin (1)
- caesarean scar (1)
- caesarean section (1)
- calbindin (1)
- calcification score (1)
- calcipotriol (1)
- calcium handling (1)
- calcium-independent phospholipase A2β (1)
- calcium-phosphate-product (1)
- calcium-sensor (1)
- caloric restriction (1)
- calretinin-knock out (1)
- cancer and drug vulnerabilities (1)
- cancer care (1)
- cancer care providers (1)
- cancer cell malignancy (1)
- cancer cells (1)
- cancer drug (1)
- cancer immunobiology (1)
- cancer information (1)
- cancer metastases (1)
- cancer patients (1)
- cancer screening (1)
- cancer surveillance (1)
- candidate genes (1)
- candidemia (1)
- cannabidiol (1)
- cannabinoid receptor type 1 (1)
- cannabinoid receptors (1)
- cannabinoids (1)
- canonical (1)
- canonical/non-canonical (1)
- cap-dependent translation (1)
- car indoor (1)
- carbapenem-resistant Gram-negative bacteria (CRGN) (1)
- carbon oxides (COx) (1)
- carbon tetrachloride (1)
- carboxyfluorescein (1)
- carcinoma (1)
- cardiac I/R injury (1)
- cardiac arrest (1)
- cardiac autonomic regulation (1)
- cardiac differentiation (1)
- cardiac events (1)
- cardiac ischaemia‐reperfusion (1)
- cardiac magnetic (1)
- cardiac magnetic resonance (1)
- cardiac myocytes (1)
- cardiac regeneration (1)
- cardiac rehabilitation (1)
- cardiac remodeling (1)
- cardiac reprogramming (1)
- cardiocerebral resuscitation (1)
- cardiomegaly (1)
- cardiomyocyte apoptosis (1)
- cardiomyocyte proliferation (1)
- cardiomyocytes (1)
- cardiomyopathy (1)
- cardiopulmonary resuscitation (1)
- cardiothoracic surgery (1)
- cardiovascular diseases (1)
- cardiovascular magnetic resonance (1)
- cardiovascular management (1)
- cardiovascular pharmacology (1)
- cardiovascular precision medicine (1)
- cardiovascular risk factors (1)
- cardiovascular system (1)
- career promotion (1)
- carnitine supplementation (1)
- carotid (1)
- carpal tunnel syndrome (1)
- carrion (1)
- cartilage oligomeric matrix protein (1)
- cartilage trauma (1)
- case reports (1)
- case study (1)
- case-control study (1)
- casein kinase 2 (1)
- caspase 8 (1)
- castration resistance (1)
- cataract surgery workflow (1)
- catecholamine excess (1)
- cathepsin L inhibitor (1)
- catheter (1)
- catheter removal (1)
- catheterization/diagnostic interventional (1)
- causality assessment (1)
- cd4 count determination procedure (1)
- cdk (1)
- cdk2/cyclin A (1)
- ceRNA (1)
- celery (1)
- celiac desease (1)
- cell adhesion (1)
- cell and focal adhesion (1)
- cell barrier integrity (1)
- cell culture (1)
- cell cycle arrest (1)
- cell cycling (1)
- cell differentiation (1)
- cell fate (1)
- cell fusion (1)
- cell growth (1)
- cell heterogeneity (1)
- cell identity (1)
- cell line (1)
- cell lines (1)
- cell proliferation regulating inhibitor of protein phosphatase 2A (1)
- cell salvage (1)
- cell signaling (1)
- cell survival (1)
- cell survival mechanisms (1)
- cell transplantation (1)
- cellular heterogeneity (1)
- cellular immunology (1)
- cellular inflammatory response (1)
- cellular reaction (1)
- cellular response (1)
- cellular signalling (1)
- cellular therapies (1)
- cellular therapy (1)
- cellular toxicity (1)
- centenarians (1)
- central nervous system infection (1)
- central spasticity (1)
- centrifugation (1)
- ceramide synthase (1)
- ceramide synthase (CERS2/CERS1) (1)
- cerclage (1)
- cerebellar mutism (1)
- cerebello-dentato-thalamo-cortical pathway (1)
- cerebral imaging (1)
- cerebral infarct (1)
- cerebral ischemia (1)
- cerebral metastasis (1)
- cerebral palsy (1)
- cerebral pseudoprogression (1)
- cerebral radiation necrosis (1)
- cerebral sinus and vein thrombosis (CVT) (1)
- cerebral vasospasm (CVS) (1)
- ceritinib (1)
- cerumen (1)
- cervical shortening (1)
- cervical spine (1)
- cervico-thoracic junction (1)
- cetuximab (1)
- cetuximab-bevacizumab therapy sequence (1)
- ch14.18/CHO (1)
- chamomile (1)
- changes immune activation (1)
- channelrhodopsin (1)
- chaperone-mediated autophagy (1)
- chaperones (1)
- characterization (1)
- charged particles (1)
- checklist (1)
- checkpoint inhibition (1)
- checkpoint proteins (1)
- chelation therapy (1)
- chelator (1)
- chemical-induced proximity (1)
- chemoattractant (1)
- chemoconvulsant (1)
- chemoembolization (1)
- chemogenomic set (1)
- chemokine (1)
- chemokine receptor 4 (1)
- chemokine receptors (1)
- chemokines: CYP2D6 model (1)
- chemoprevention (1)
- chemoprotection (1)
- chemorefractory metastatic colorectal cancer (1)
- chemosensory cells (1)
- chemotherapeutic drug resistance (1)
- chemotherapeutics (1)
- chemotherapeutics-treated (1)
- chemotherapy regimen (1)
- chemotherapy-resistance (1)
- chernobyl (1)
- chest injury (1)
- child abuse and neglect (1)
- child maltreatment (1)
- child psychiatry (1)
- childhood (1)
- childhood abuse (1)
- childhood epilepsy (1)
- chimeric antigen receptor (CAR) (1)
- chimeric antigen receptor t-cell therapy (1)
- chimeric antigen receptors (1)
- chinese medicine (1)
- chloroplasts (1)
- cholecystectomy (1)
- cholestasis (1)
- cholinergic system (1)
- cholinesterase (1)
- chondrocyte (1)
- chondrocytes (1)
- chromaffin cell (1)
- chromatin (1)
- chromatin immunoprecipitation (1)
- chromosomal breaks (1)
- chromosomal instability (1)
- chromosomal integration (1)
- chromosomal translocations (1)
- chromosome alignment (1)
- chromosome instability (1)
- chromosome segregation (1)
- chronic (1)
- chronic care (1)
- chronic colitis (1)
- chronic coronary artery disease (1)
- chronic hypoxia (1)
- chronic illness (1)
- chronic infection (1)
- chronic infections (1)
- chronic kidney disease (CKD) (1)
- chronic liver disease (1)
- chronic liver disease (CLD) (1)
- chronic myeloid leukemia (CML) (1)
- chronic total occlusion (1)
- chronic viral hepatitis (1)
- chronobiology (1)
- chronotype (1)
- cigarette smoke (1)
- cigarette strength (1)
- cigarettes (1)
- cigarillos (1)
- cilia (1)
- circadian variation (1)
- circulating miRNA (1)
- circulation (1)
- cisplatin sensitivity (1)
- classical conditioning (1)
- classification (1)
- classification of bone defects (1)
- clean room (1)
- clear cell renal cell carcinoma (1)
- clear cell sarcoma (1)
- clear lens exchange (1)
- clear or almost clear skin (1)
- climate change genomics (1)
- clindamycin (1)
- clinical (1)
- clinical cases (1)
- clinical competency (1)
- clinical decision support (1)
- clinical decision-making (1)
- clinical features (1)
- clinical high at-risk mental state (1)
- clinical history (1)
- clinical management (1)
- clinical node positive (1)
- clinical outcome (1)
- clinical pathways (1)
- clinical practice (1)
- clinical relevance (1)
- clinical stage (1)
- clinical teaching (1)
- clinical tool (1)
- clinically relevant dissolution specifications (1)
- cloacae (1)
- cloacal malformation (1)
- clonal dominance (1)
- clonal haematopoiesis (1)
- clonal hematopoiesis (1)
- clonal transfer (1)
- clopidogrel (1)
- cluster analysis (1)
- cluster of differentiation 4 (CD4) (1)
- cluster-randomized controlled trial (1)
- clusteranalysis (1)
- cluttering (1)
- co-crystallization (1)
- coaching (1)
- coagulation (1)
- coauthor ship (1)
- cocaine (1)
- cochlear implants (1)
- coffee (1)
- cognitive ability (1)
- cognitive aging (1)
- cognitive control (1)
- cognitive decline (1)
- cognitive deficits (1)
- cognitive fluency (1)
- cognitive functions (1)
- cognitive impairment (CI) (1)
- cognitive interventions (1)
- cognitive models (1)
- cognitive states (1)
- cognitively stimulating leisure activities (1)
- cohort study (1)
- cold atmospheric plasma (1)
- cold induced pain (1)
- cold tolerance (1)
- colitis (1)
- collaborative feedback (1)
- collagen I (1)
- collagen VI (1)
- collagen adhesion (1)
- collagen degradation marker (1)
- collagen membranes (1)
- collagen type I (1)
- collagen-based biomaterial (1)
- collagen-based matrix (1)
- collateral growth (1)
- collateral sprouting (1)
- collective cell migration (1)
- collective dynamics (1)
- colloid (1)
- colon cancer cells (1)
- colon carcinoma (1)
- colonization (1)
- colony formation (1)
- colorectal cancer liver metastases (CRLM) (1)
- column chromatography (1)
- combination (1)
- combination immunotherapy (1)
- combination therapies (1)
- combination treatment (1)
- combined immunodeficiency (1)
- combined modality therapy (1)
- common genetic variation (1)
- common neighbor (1)
- common variant (1)
- common variants (1)
- communication (1)
- community violence exposure (1)
- compaction (1)
- comparative pathology (1)
- comparative study (1)
- competitive peptide (1)
- complement dependent cytotoxicity (1)
- complement; patients (1)
- complementary information (1)
- complementary psychosocial care (1)
- complementary/alternative medicine (CAM) (1)
- complete response (1)
- complex I deficiency (1)
- complex coronary interventions (1)
- complexity theory (1)
- compound screen (1)
- comprehensive care (1)
- computational biology (1)
- computational functional genomics (1)
- computational intelligence (1)
- computational knowledge-discovery (1)
- computational modeling (1)
- computational models (1)
- computational neuroimaging (1)
- computational pathology (1)
- computational techniques (1)
- computer tomography (1)
- computer vision (1)
- computer-assisted drug therapy (1)
- concentric (1)
- concurrent (1)
- concurrent TMS--fMRI (1)
- conditioning (1)
- conduit (1)
- cone-beam computed tomography (CBCT) (1)
- cone-beam computer tomography (1)
- confidence (1)
- congenic mice (1)
- congenital deafness (1)
- congenital disorders of autophagy (1)
- congenital duodenal obstruction (1)
- congruency (1)
- conical coupling (1)
- connectional fingerprint (1)
- connective tissue graft (1)
- connective tissue growth factor (1)
- conometric connection (1)
- conotoxin (1)
- consciousness (1)
- consensus classification (1)
- consensus data set (1)
- consensus paper (1)
- conservative dentistry (1)
- consolidation treatment (1)
- contact heat evoked potentials (CHEPS) (1)
- contact lens solution (1)
- contamination (1)
- continuing education (1)
- continuity of care (1)
- continuous glucose monitoring (1)
- contraception (1)
- contralateral delay activity (1)
- control of menstrual bleeding (1)
- controlled nuclear import (1)
- conventional laparoscopic (1)
- conventional/traditional transarterial chemoembolization (cTACE) (1)
- convolution neural network (1)
- cooling deactivation (1)
- cooling period (1)
- coordination (1)
- copeptin (1)
- copper free strain-promoted azide alkyne cycloaddition (SPAAC) (1)
- copy number polymorphism (1)
- cord clamping (1)
- core expression (1)
- cornea donor (1)
- corneas (1)
- coronally advanced flap (1)
- coronary (1)
- coronary artery bypass surgery (1)
- coronary calcium (1)
- coronary computed-tomography angiography (CCTA) (1)
- coronary disease (1)
- coronary imaging (1)
- coronary plaques (1)
- coronavirus disease 2019 (1)
- correlation (1)
- corrosion (1)
- cortex, gray matter (1)
- cortex-based alignment (1)
- cortical folding (1)
- cortical impact (1)
- cortical layers and areas (1)
- cortical malformation (1)
- cortical network (1)
- cortical networks (1)
- cortical slices (1)
- cortical thickness (1)
- corticomuscular coherence (CMC) (1)
- corticospinal tracts (1)
- corticosteroid drugs (1)
- corticosteroids (1)
- cost analysis (1)
- cost containment (1)
- cost of illness (1)
- cost-of-illness (1)
- costimulation (1)
- costs (1)
- counseling (1)
- counselling (1)
- coupling (1)
- courting behavior (1)
- covalent drugs (1)
- cranberry (1)
- crestal bone loss (1)
- crime scene (1)
- crista junction (1)
- cristae (1)
- criteria (1)
- critical care unit (1)
- critical ill patients (1)
- critical periods (1)
- critical-size defect (1)
- cross reactivity (1)
- cross-border (1)
- cross-communication (1)
- cross-frequency coupling (1)
- cross-linking (1)
- cross-modal (1)
- cross-modal plasticity (1)
- cross-sectional study (1)
- crowns (1)
- cryoelectron microscopy (1)
- cryogenic electron microscopy (1)
- cryotherapy (1)
- crystalloid (1)
- culpa asociada a trauma (1)
- cultural and social transformation of sexuality (1)
- cumulative dose (1)
- curriculum (1)
- cutaneous T cell lymphoma (1)
- cuticular hydrocarbons (1)
- cyclic depsipeptide (1)
- cyclic nucleotide analogues (1)
- cyclic nucleotide binding proteins (1)
- cyclin D1 (1)
- cyclin Y (1)
- cycling (1)
- cyclins (1)
- cyclooxygenase 1 (COX-1) (1)
- cyclooxygenase 2 (1)
- cyclooxygenase 2 (COX-2) (1)
- cyclooxygenase-2 (1)
- cyclopentenone prostaglandins (1)
- cyclophilin A (1)
- cyclophosphamide (1)
- cyclosporine (1)
- cys-loop receptor (1)
- cystatin C (1)
- cytarabin (1)
- cytarabine dose (1)
- cytochrome P450 (1)
- cytochrome P450 enzymes (1)
- cytochrome P450 reductase (1)
- cytochrome c oxidase (complex IV) (1)
- cytochrome c oxidase I (COI) (1)
- cytokine gene expression (1)
- cytokine release syndrome (1)
- cytokine storm (1)
- cytokine(s) (1)
- cytokine, angiogenesis (1)
- cytoskeleton (1)
- cytosolic free calcium (1)
- cytotoxic T lymphocyte (1)
- cytotoxic immunotherapy (1)
- cytotoxic lymphocytes (1)
- dNTP pools (1)
- dabigatran (1)
- daily activity protocols (1)
- damage associated molecular pattern (1)
- damage-associated molecular pattern (1)
- dance teacher (1)
- dapagliflozin (1)
- data analysis (1)
- data management (1)
- data modeling (1)
- data quality (1)
- data quality check (1)
- data repositories (1)
- data sharing (1)
- day clinic (1)
- de novo transcription (1)
- deaf white cat (1)
- death (1)
- death rates (1)
- death receptor (1)
- debridement (1)
- debris (1)
- decision aids (1)
- decision support systems (1)
- decision tree (1)
- decision-making (1)
- declaration of tobacco ingredients (1)
- decomposition (1)
- decompressive craniectomy (1)
- deconvolution (1)
- decorin (1)
- decorrelation (1)
- dedifferentiation (1)
- deep learning (1)
- deep mutational scanning (1)
- deep neural network (1)
- deep sedation (1)
- deep vein thrombosis (1)
- default mode network (1)
- defect configuration (1)
- deferred treatment (1)
- degradation (1)
- delayed auditory feedback (1)
- delayed cerebral ischemia (DCI) (1)
- delayed cholecystectomy (1)
- delayed diagnosis (1)
- delayed treatment (1)
- delayed wound healing (1)
- deletion 5q (1)
- delivery mode (1)
- delta (1)
- delta-9-tetrahydrocannabinol (1)
- demineralized bone matrix (1)
- dendrite (1)
- dendrite morphogenesis (1)
- dendritic cell (1)
- dendritic cell–tumor cell fusion (1)
- dendritic inhibition (1)
- denervation (1)
- dengue vector (1)
- density equalizing mapping (1)
- dental abutment (1)
- dental academic degrees (1)
- dental educationcation (1)
- dental emergency treatment (1)
- dental health professional (1)
- dental school (1)
- dental treatment concept (1)
- dentin adhesives (1)
- dentistry (1)
- dentist’s chair design (1)
- depolymerization (1)
- depressive symptoms (1)
- depressive symptoms clusters (1)
- deprivation (1)
- deproteinized bovine bone matrix (DBBM) (1)
- depth perception (1)
- dermatology (1)
- dermatomes (1)
- desmoplastic small round cell tumor (1)
- desmoplastic stroma (1)
- deswelling (1)
- detection task (1)
- deubiquitinating enzyme (1)
- deubiquitinating enzymes (1)
- deubiquitylation (deubiquitination) (1)
- devastated bladder outlet (1)
- device handling (1)
- diabetes complication (1)
- diabetes therapy (1)
- diabetic macular edema (1)
- diabetic neuropathy (1)
- diagnostic biomarkers (1)
- diagnostic imaging (1)
- diagnostic method (1)
- diagnostic test (1)
- diagnostic window (1)
- diagnostisches Fenster (1)
- dialysis (1)
- diaphragm development (1)
- diarrhoeal disease (1)
- diastolic function (1)
- diclofenac (1)
- differential expression (1)
- differentiated thyroid carcinoma (1)
- diffuse large B cell lymphoma (1)
- diffuse low-grade glioma (1)
- diffuse marrow involvement (1)
- diffusion MRI (1)
- diffusion microstructure (1)
- diffusion tensor imaging (DTI) (1)
- diffusion-weighted magnetic resonance imaging (1)
- digestive tract (1)
- digital age determination (1)
- digital decision-support (1)
- digital one-piece casting (1)
- digital pathology (1)
- digital pressing technology (1)
- digital workflow (1)
- dihydrocannabidiol (1)
- dihydroceramides (1)
- dimethylfumarate (1)
- dipeptide (1)
- diphtheria toxin (1)
- diplopia (1)
- direct antiviral (1)
- direct antiviral agents (1)
- direct-acting antiviral (DAA) treatment (1)
- direct-acting antivirals (DAAs) (1)
- directed disulfide bond formation (1)
- directed forgetting (1)
- directly acting antiviral agents (1)
- disasters (1)
- discoidin domain-containing receptor (1)
- discomfort/pain (1)
- discontinuation (1)
- discontinuous dose dependency (1)
- disease modelling (1)
- disease outbreaks (1)
- disease vectors (1)
- disease-free survival (1)
- disease-modifying antirheumatic drugs (1)
- disease-modifying therapy (1)
- disordered iron metabolism (1)
- disposable insulin pens (1)
- disruptive behaviour disorder (1)
- dissemination (1)
- dissimilatory sulfite reductase (1)
- distal pronephric outlet obstruction (1)
- distraction (1)
- distributed analysis (1)
- distributed computation (1)
- diuretics (1)
- diurnal (1)
- dobutamine stress (1)
- docetaxel (DX) resistance (1)
- docking studies (1)
- doctoral degrees (1)
- dog study (1)
- donor deferral (1)
- donor recruitment (1)
- donor retention (1)
- donor safety (1)
- dopamine transporter (1)
- doppler (1)
- dorsal attention network (1)
- dorsal auditory stream (1)
- dose response curve (1)
- dosimetry (1)
- dosing accuracy (1)
- double immune checkpoint inhibition (1)
- double inversion recovery (DIR) (1)
- double negative (1)
- double orifice mitral valve (1)
- double-pigtail stents (1)
- doublecortin (1)
- downgrading (1)
- drilling tool design (1)
- drinking (1)
- drospirenone (1)
- drug (1)
- drug abstinence (1)
- drug delivery (1)
- drug hepatotoxicity (1)
- drug interaction (1)
- drug metabolism and distribution (1)
- drug repurposing (1)
- drug resistance and invasiveness (1)
- drug screening (1)
- drug targets (1)
- drug therapy (1)
- drug-coated balloon (1)
- drug-eluting balloon (1)
- drug-eluting beads TACE (DEB-TACE) (1)
- drug-induced liver injury (DILI) (1)
- druggable genome (1)
- drugs (1)
- drug‐resistant epilepsy (1)
- drug–drug interactions (1)
- drug–gene interactions (1)
- drug–g–gene interactions (1)
- dsr genes (1)
- dual antiplatelet therapy (1)
- dual bronchodilators (1)
- dual-energy (1)
- dynamic 18F-FDG PET/CT (1)
- dynamic causal modeling (1)
- dynamic connectivity (1)
- dynamic stimuli (1)
- dynamic system (1)
- dysbetalipoproteinemia (1)
- dysbiosis (1)
- dysferlin (1)
- dysferlinopathy (1)
- dysfibrinogenemia (1)
- dyssynchrony analysis (1)
- e-Health (1)
- e-Learning (1)
- e-scooter (1)
- eLearning (1)
- eNOS (1)
- eNPP2 (1)
- ePTFE membrane (1)
- early cholecystectomy (1)
- early continence (1)
- early detection (1)
- early epilepsy (1)
- early infection (1)
- early loss (1)
- early myocardial damage (EMD) (1)
- early onset (1)
- early recognition (1)
- early tumor stages (1)
- early-onset prostate cancer (1)
- eccentric (1)
- echo planar imaging (1)
- economy (1)
- ectopic pregnancy (1)
- edema (1)
- edentulous (1)
- editorials (1)
- edoxaban (1)
- educational cases (1)
- educational measurement (1)
- educational theory (1)
- effect mechanism (1)
- effective lens position (1)
- effectiveness (1)
- efferocytosis (1)
- efficiency (1)
- efflux pump (1)
- egg sampling (1)
- egr-1 (1)
- eicosanoid (1)
- eight disorders (1)
- ejection fraction (EF) (1)
- elastin (1)
- electric scooter (1)
- electrical coupling (1)
- electrical stimulation (1)
- electroanatomical mapping (1)
- electroconvulsive therapy (1)
- electrode design (1)
- electroencephalography (EEG) (1)
- electroencephalography (EEG), EEG reference choices, event-related potentials (ERP), independent component analysis (ICA), pain research, contact heat evoked potentials (CHEPS) (1)
- electromagnetic navigation bronchoscopy (EMN, ENB) (1)
- electron transfer (1)
- electron transfer chain (1)
- electronic adherence measurement (1)
- electronic diaries (1)
- electronic pen (1)
- electrophiles (1)
- electrophilic fatty acids (1)
- electrophoresis (1)
- element speciation (1)
- eligibility (1)
- elite athlete (1)
- elite athletes (1)
- eltrombopag (1)
- embodiment (1)
- embolization (1)
- emergence (1)
- emergent self-organizing maps (1)
- emicizumab (1)
- emotion (1)
- emotional climate (1)
- emotional information processing (1)
- empagliflozin (1)
- empowerment (1)
- emulsion diffusion (1)
- enamel matrix derivatives (1)
- encephalopathy (1)
- encoding strategies (1)
- end of life care (1)
- endocarditis (1)
- endodontic curriculum (1)
- endodontic education (1)
- endodontics (1)
- endogenous clock (1)
- endometrial cancer (1)
- endometriosis (1)
- endophytes (1)
- endoscopic retrograde cholangiography (1)
- endoscopy (1)
- endothelial activation (1)
- endothelial barrier (1)
- endothelial dysfunction (1)
- endothelial function (1)
- endothelial nitric-oxide synthase (1)
- endothelial receptor expression (1)
- endothelial to mesenchymal transition (1)
- endothelin (1)
- endothelin receptor type A antagonist (1)
- endothelium (1)
- endotoxemia (1)
- endotoxins (1)
- endourology (1)
- endovascular recanalization (1)
- endovascular thrombectomy (1)
- enforced viral replication (1)
- english (1)
- ensemble cNN (1)
- enterobacter infections; pseudomonas aeruginosa; epidemiology (1)
- enterocytes (1)
- enterovirus (1)
- entomological evidence (1)
- envelope technique (1)
- environment (1)
- enzyme activity assay (1)
- eosinophil cationic protein (1)
- eosinophilic cholangitis (1)
- eosinophils (1)
- epidermis (1)
- epididymitis (1)
- epidural (1)
- epigenetic memory (1)
- epigenome (1)
- epigenomics (1)
- epilepsy surgery (1)
- epileptic encephalopathies (1)
- epiregulin (1)
- episodic memory (1)
- epithelial cells (1)
- epithelial mesenchymal transition (1)
- epithelial-to-mesenchymal transition (EMT) (1)
- epithelial‐mesenchymal transition (1)
- epitope mapping (1)
- epoxyeicosatrienoic acid (1)
- ergometry (1)
- erosions (1)
- erythropoiesis (1)
- erythropoietin (1)
- erythropoietin (EPO) (1)
- escape mutations (1)
- essential thrombocythemia (ET) (1)
- essential tremor (1)
- esterification (1)
- estrogen (1)
- ethanol (1)
- ethical trade-off (1)
- ethnicity (1)
- ethyl pyruvate (1)
- eutheria (1)
- evaluation practice (1)
- event logs (1)
- event-based (1)
- event-related potential (1)
- event-related potentials (ERP) (1)
- everyday life (1)
- everyday tasks (1)
- evidence-based guideline (1)
- evoked response (1)
- ex vivo expansion (1)
- ex vivo model (1)
- ex vivo stimulation (1)
- ex-Gaussian analysis (1)
- excess fluid volume (1)
- excitability (1)
- exclusion of very low profiles (1)
- executive control (1)
- executive functions (1)
- exercise on prescription (1)
- exercise physiology (1)
- exercise testing (1)
- exercise training (1)
- exome sequencing (1)
- exosome (1)
- experimental human pain models (1)
- experimental pain models (1)
- expert review (1)
- expert witness statement (1)
- explainable AI (1)
- exponential model (1)
- exposure (1)
- expressed emotion (1)
- expression studies (1)
- extensive surgery (1)
- extensively drug-resistant (1)
- external fixation (1)
- external joint moments (1)
- extracellular chromatin (1)
- extracellular signal-regulated kinase (1)
- extracting solvents (1)
- extraction socket healing (1)
- extraskeletal (1)
- extremity (1)
- eye movement (1)
- eye movements (1)
- eye tracking (1)
- eye tracking (ET) (1)
- eye-tracking (1)
- fMLP (1)
- face (1)
- face inversion effect (1)
- face-name association task (1)
- facial EMG (1)
- facial emotion recognition (1)
- facial expressions of emotion (1)
- facial muscle activity (1)
- facial nerve functional outcome (1)
- facial prosthesis (1)
- factor IX (1)
- factor V Leiden mutation (1)
- factor VIII (1)
- factor VIII (FVIII) (1)
- factor XIII (1)
- faecal microbiota transfer (1)
- falls (1)
- false memory (1)
- familial amyloid nephropathy with urticaria and deafness (1)
- familial colorectal cancer (1)
- familial infantile epilepsy (1)
- family-friendly universities (1)
- famotidine (1)
- fasting insulin (1)
- fat (1)
- fat grafting (1)
- fat pad resection (1)
- fatty acid (1)
- fatty acid elongase (Elovl1/4/5) (1)
- fatty acid synthesis (1)
- fatty acids (1)
- fear conditioning (1)
- fear extinction (1)
- fear generalization (1)
- fear learning (1)
- feasibility study (1)
- febrile neutropenia (1)
- fecal incontinence (1)
- fecal microbiota transfer (1)
- fecal occult blood test (1)
- federated feasibility queries (1)
- feedback control (1)
- feeder cells (1)
- feeding (1)
- female health (1)
- females (1)
- femoropopliteal segment (1)
- ferret (1)
- ferric derisomaltose (1)
- ferritin (1)
- ferritinophagy (1)
- ferroportin (1)
- ferumoxytol (1)
- fetal loss (1)
- fetal weight estimation (1)
- fiber orientations (1)
- fibre tracking (1)
- fibrin (1)
- fibrin-glue-spray technique (1)
- fibroblast (1)
- fibrocytes (1)
- fibrogenesis (1)
- fibromodulin (1)
- fibronectin (1)
- fibrosarcoma (1)
- fibrosis imaging (1)
- fibrotest (1)
- fidaxomicin (1)
- fimaporfin (1)
- finger tapping (1)
- fingolimod (1)
- first-line chemotherapy (1)
- first-time shoulder dislocation (1)
- fitness (1)
- fixation (1)
- fixed partial dentures (1)
- fizička aktivnost; (1)
- flavivirus entry factor (1)
- fluid (1)
- fluid shear stress (1)
- fluocinolone acetonide (1)
- fluorescence (1)
- fluorescence in situ hybridization (FISH) (1)
- fluorescent dye (1)
- fluorine (1)
- focal adhesion kinase (1)
- focal cortical dysplasia (1)
- focal cortical dysplasia (FCD) (1)
- focal seizures (1)
- follow‑up (1)
- fondaparinux (1)
- fondaparinux sodium (1)
- foreign body reaction (1)
- forensics (1)
- formalin-fixed and paraffin-embedded tissue (FFPE) (1)
- formalin-fixed paraffin-embedded (FFPE) samples (1)
- formula diet (1)
- fortgeschritten (1)
- fourth (1)
- fractional anisotropy (1)
- fractionation (1)
- fracture strength (1)
- fracture strength equation (1)
- fragile-X-associated tremor-ataxia syndrome (1)
- fragment screening (1)
- fragment-size analyses (ACE2; CQ11) (1)
- free flap (1)
- free gingival graft (1)
- free leptin index (FLI) (1)
- freeze avoidance (1)
- frequency of attacks (1)
- fresh frozen plasma (1)
- frontal cortex (1)
- fronto-temporal lobar dementia (1)
- fronto-temporal-lobar-dementia (1)
- frontotemporal dementia (1)
- frontotemporal lobar degeneration (1)
- full-arch restoration (1)
- full-contour crown restorations (1)
- full-contour zirconia (1)
- fully human (1)
- fumonisin B1 (1)
- function (1)
- function, sorting (1)
- functional MRI (1)
- functional connectome acute (1)
- functional imaging (1)
- functional magnetic resonance imaging (fMRI) (1)
- fundoplication (1)
- fungal infection (1)
- fungal pathogens (1)
- fungal sinusitis (1)
- fungal sugar (1)
- fungi (1)
- fungus (1)
- furcation involvement (1)
- further education (1)
- fusion kinase (1)
- fäkaler okkulter Stuhltest (1)
- gRNA library (1)
- gadobutrol (1)
- gadolinium (1)
- gadolinium enhancing lesion (1)
- gadolinium‐based contrast agent (1)
- gait symmetry (1)
- galactography (1)
- galactomannan (1)
- galactomosynthesis (1)
- gallbladder cancer (1)
- gallbladder cancer xenografts (1)
- gallstone disease (1)
- galunisertib monohydrate (LY2157299) (1)
- gangliosides (1)
- gap junction protein alpha 4-genotype (1)
- gargle lavage (1)
- gas chromatography-mass spectrometry (1)
- gasotransmitters (1)
- gastric (1)
- gastric surgery (1)
- gastro-oesophageal junction cancer (1)
- gastroesophageal reflux (1)
- gastrointestinal (1)
- gastrointestinal stromal tumours (1)
- gastrointestinal tract (1)
- gefitinib (1)
- gel (1)
- gel spacer injection (1)
- gemcitabine (1)
- gender difference (1)
- gender differences (1)
- gender dysphoria (1)
- gender equality (1)
- gender equality plan (1)
- gender studies (1)
- gender-affirming hormone therapy (1)
- gene delivery (1)
- gene expression analysis (1)
- gene expression profiling (1)
- gene expression profiling (GEP) (1)
- gene vectors (1)
- general anaesthesia (1)
- general practitioner (1)
- general practitioners (1)
- generic preparedness (1)
- genes (1)
- genetic generalized epilepsy (1)
- genetic markers (1)
- genetic model (1)
- genetic phenotypes (1)
- genetic polymorphisms (1)
- genetic predisposition (1)
- genetic rearrangements (1)
- genetic variability (1)
- genetic variants (1)
- genetically caused iron imbalance (1)
- genetics and genomics (1)
- gene×environment interactions (1)
- genome editing (1)
- genome-wide (1)
- genome-wide association study (1)
- genomic classifiers (1)
- genomic instability (1)
- genotype (1)
- genotype G (1)
- genotype determination (1)
- geriatric medicine (1)
- geriatric patients (1)
- geriatrics (1)
Institute
- Medizin (5376) (remove)
Highlights
• A proteomic analysis of the mandibular glands of Shinisaurius crocodilurus and Corucia zebrata, was performed.
• Scanning electron microscopy of S. crocodilurus' teeth revealed a sharp ridge on the anterior surface, but no grooves.
• Scanning electron microscopy of C. zebrata teeth showed a flattened crown with a pointed cusp.
• Proteomic analysis of gland extracts of S. crocodilurus and C. zebrata showed absence of venom-derived peptides or proteins.
• Our results strongly support the non-venomous character of both S. crocodilurus and C. zebrata.
Abstract
Based on its phylogenetic relationship to monitor lizards (Varanidae), Gila monsters (Heloderma spp.), and the earless monitor Lanthanotus borneesis, the Chinese crocodile lizard, Shinisaurus crocodilurus, has been assigned to the Toxicofera clade, which comprises venomous reptiles. However, no data about composition and biological activities of its oral secretion have been reported. In the present study, a proteomic analysis of the mandibular gland of S. crocodilurus and, for comparison, of the herbivorous Solomon Island skink Corucia zebrata, was performed. Scanning electron microscopy (SEM) of the teeth from S. crocodilurus revealed a sharp ridge on the anterior surface, but no grooves, whereas those of C. zebrata possess a flattened crown with a pointed cusp. Proteomic analysis of their gland extracts provided no evidence of venom-derived peptides or proteins, strongly supporting the non-venomous character of these lizards. Data are available via ProteomeXchange with identifier PXD039424.
Highlights
• Proteomic analyses of submandibular gland extracts of two alligator lizards of the Anguidae family are reported.
• A conserved set of putative toxins was found in the submandibular gland extracts of Abronia lythrochila and A. graminea.
• Toxins evolved in oral secretions of paleo- and neoanguimorpha over more than 100 million years of Anguimorpha cladogenesis.
• Electron microscopy of pleurodont teeth of A. lythrochila showed no sign of groove, external opening or striations.
• Assessing the role toxins play in the ecology of extant anguimorph lizards deserves functional studies in natural prey.
Abstract
A useful approach to deepen our knowledge about the origin and evolution of venom systems in Reptilia has been exploring the vast biodiversity of this clade of vertebrates in search of orally produced proteins with toxic actions, as well as their corresponding delivery systems. The occurrence of toxins in anguimorph lizards has been demonstrated experimentally or inferred from reports of the toxic effects of the oral secretions of taxa within the Varanidae and Helodermatidae families. In the present study, we have focused on two alligator lizards of the Anguidae family, the Mexican alligator lizard, Abronia graminea, and the red-lipped arboreal alligator lizard, A. lythrochila. In addition, the fine morphology of teeth of the latter species is described. The presence of a conserved set of proteins, including B-type natriuretic peptides, cysteine-rich secretory proteins, group III phospholipase A2, and kallikrein, in submandibular gland extracts was demonstrated for both Abronia species. These proteins belong to toxin families found in oral gland secretions of venomous reptile species. This finding, along with previous demonstration of toxin-producing taxa in both paleo- and neoanguimorpha clades, provides further support for the existence of a handful of conserved toxin families in oral secretions across the 100+ million years of Anguimorpha cladogenesis.
Introduction: Patients undergoing left atrial appendage closure (LAAC) are often severly anemic and close to the transfusion threshold. The aim was to investigate the prevalence of severe anemia in this cohort and if procedural safety is compromised compared with non-anemic patients.
Methods and results: Comparison of severly anemic patients (Hb < 80 g/l) vs. non-severly anemic patients in the prospective, multicentre observational LAARGE registry of patients undergoing LAAC. A total of 638 patients (anemia 22.3% vs non-anemic 77.7%) were included. Anemic patients were older (77.1 years ± 7.9 vs 75.6 years ± 7.9, p = 0.014), had more comorbidities, higher CHA2DS2-VASc (4.8 vs 4.4, p = 0.017) and higher HAS-BLED (4.3 vs 3.8, p < 0.001) scores. Implant success was not influenced by anemia (99.3% vs 97.2%). Severe in-hospital (0.7% vs 5.6%, p = 0.01) and overall complications (8.5% vs 13.7%, p = 0.11) were less common in patients with anemia, driven by fewer pericardial effusions. Mortality was higher in anemic patients and associated with an increased hazard ratio, albeit not significantly (16.0% vs 10.3%, HR 1.61 (95%-CI: 0.97–2.67), p = 0.06). In the one-year follow-up, composite outcome of death, stroke or systemic embolism occurred in 22/142 anemic and in 54/496 non-anemic patients with an adjusted HR of 1.04 (95%-CI 0.62–1.73, p = 0.89).
Conclusion: Severe anemia close to the transfusion threshold is common in patients undergoing LAAC. However, this does not influence in-hospital complications or implant success. One-year mortality is higher in anemic patients, mainly driven by co-morbidities.
Key Teaching Points
• Wearables such as smartwatches can monitor beyond heart rate and heart rhythm.
• Specific smartwatches provide reliable measurements of electrocardiographic intervals (eg, QT interval).
• Correct analysis and interpretation of the QT interval in an individual with previously unknown long QT syndrome facilitated the diagnosis.
Aim: The aim of this study was to evaluate the relationship between coronary artery calcification (CAC) assessed by multi-detector computed tomography (MDCT) and myocardial perfusion assessed by cardiac magnetic resonance imaging (CMR) in a group of symptomatic patients.
Method: Retrospective analysis of 120 patients (age 65.1 ± 8.9 years, 88 males) who presented with atypical chest pain to Bethanien Hospital, Frankfurt, Germany, between 2007 and 2010 and who underwent CAC scoring using MDCT, CMR, and conventional coronary angiography. Patients were divided into those with high-grade (HG) stenosis (n = 67, age 65.1 ± 9.4 years) and those with no-HG stenosis (n = 53, age 65.1 ± 8.6 years).
Results: There were more males with HG stenosis (82.1% vs. 62.3%, p = 0.015), in whom the percentage and number of abnormal perfusion segments were higher at rest (37.3% vs. 17%, p = 0.014) but not different with stress (p = 0.83) from those with no-HG stenosis. Thirty-four patients had myocardial perfusion abnormalities at rest and 26 patients developed perfusion defects with stress. Stress-induced myocardial perfusion defects were 22.4% sensitive and 79.2% specific for detecting HG stenosis. The CAC score was lower in patients with no-HG stenosis compared to those with HG stenosis (p < 0.0001). On the ROC curve, a CAC score of 293 had a sensitivity of 71.6% and specificity of 83% in predicting HG stenosis [(AUC 0.80 (p < 0.0001)]. A CAC score of 293 or the presence of at least 1 segment myocardial perfusion abnormality was 74.6% sensitive and 71.7% specific in detecting HG stenosis, the respective values for the 2 abnormalities combined being 19.4% and 90.6%. The severity of CAC correlated with the extent of myocardial perfusion in the patient group as a whole with stress (r = 0.22, p = 0.015), particularly in those with no-HG stenosis (r = 0.31, p = 0.022). A CAC score of 293 was 31.6% sensitive and 87.3% specific in detecting myocardial perfusion abnormalities.
Conclusion: In a group of patients with exertional angina, coronary calcification is more accurate in detecting high-grade luminal stenosis than myocardial perfusion defects. In addition, in patients with no stenosis, the incremental relationship between coronary calcium score and the extent of myocardial perfusion suggests coronary wall hardening as an additional mechanism for stress-induced angina other than luminal narrowing. These preliminary findings might have a clinical impact on management strategies of these patients other than conventional therapy.
Rationale and Objectives: Lumbar disk degeneration is a common condition contributing significantly to back pain. The objective of the study was to evaluate the potential of dual-energy CT (DECT)-derived collagen maps for the assessment of lumbar disk degeneration.
Patients and Methods: We conducted a retrospective analysis of 127 patients who underwent dual-source DECT and MRI of the lumbar spine between 07/2019 and 10/2022. The level of lumbar disk degeneration was categorized by three radiologists as follows: no/mild (Pfirrmann 1&2), moderate (Pfirrmann 3&4), and severe (Pfirrmann 5). Recall (sensitivity) and accuracy of DECT collagen maps were calculated. Intraclass correlation coefficient (ICC) was used to evaluate inter-reader reliability. Subjective evaluations were performed using 5-point Likert scales for diagnostic confidence and image quality.
Results: We evaluated a total of 762 intervertebral disks from 127 patients (median age, 69.7 (range, 23.0–93.7), female, 56). MRI identified 230 non/mildly degenerated disks (30.2%), 484 moderately degenerated disks (63.5%), and 48 severely degenerated disks (6.3%). DECT collagen maps yielded an overall accuracy of 85.5% (1955/2286). Recall (sensitivity) was 79.3% (547/690) for the detection of no/mild lumbar disk degeneration, 88.7% (1288/1452) for the detection of moderate disk degeneration, and 83.3% (120/144) for the detection of severe disk degeneration (ICC = 0.9). Subjective evaluations of DECT collagen maps showed high diagnostic confidence (median 4) and good image quality (median 4).
Conclusion: The use of DECT collagen maps to distinguish different stages of lumbar disk degeneration may have clinical significance in the early diagnosis of disk-related pathologies in patients with contraindications for MRI or in cases of unavailability of MRI.
Highlights
• Early reconstruction of injured cruciate ligaments improves functional outcomes.
• Modern CT imaging can be used to rapidly identify patients with injury to the cruciate ligaments and streamline therapeutic pathways.
• Dual-energy CT demonstrates superior diagnostic accuracy compared to single-energy CT.
Abstract
Background: This study aimed to evaluate the clinical utility of modern single and dual-energy computed tomography (CT) for assessing the integrity of the cruciate ligaments in patients that sustained acute trauma.
Methods: Patients who underwent single- or dual-energy CT followed by 3 Tesla magnetic resonance imaging (MRI) or knee joint arthroscopy between 01/2016 and 12/2022 were included in this retrospective, monocentric study. Three radiologists specialized in musculoskeletal imaging independently evaluated all CT images for the presence of injury to the cruciate ligaments. An MRI consensus reading of two experienced readers and arthroscopy provided the reference standard. Diagnostic accuracy parameters and area under the receiver operator characteristic curve (AUC) were the primary metrics for diagnostic performance.
Results: CT images of 204 patients (median age, 49 years; IQR 36 – 64; 113 males) were evaluated. Dual-energy CT yielded significantly higher diagnostic accuracy and AUC for the detection of injury to the anterior (94% [240/255] vs 75% [266/357] and 0.89 vs 0.66) and posterior cruciate ligaments (95% [243/255] vs 87% [311/357] and 0.90 vs 0.61) compared to single-energy CT (all parameters, p <.005). Diagnostic confidence and image quality were significantly higher in dual-energy CT compared to single-energy CT (all parameters, p <.005).
Conclusions: Modern dual-energy CT is readily available and can serve as a screening tool for detecting or excluding cruciate ligament injuries in patients with acute trauma. Accurate diagnosis of cruciate ligament injuries is crucial to prevent adverse outcomes, including delayed treatment, chronic instability, or long-term functional limitations.
Highlights
• Assessment of coronary artery plaque burden according to the CAC-DRS Score correlated well with pulmonary involvement of SARS-CoV-2 pneumonia (min. r=0.81, 95% CI 0.76 to 0.86).
• Visual and quantitative CAC-DRS Score of coronary artery plaque burden provided independent prognostic information on all-cause mortality in patients with SARS-CoV-2 pneumonia (p=0.0016 and p<0.0001, respectively).
• Incorporating CAC-DRS Score and pulmonary involvement into clinical decision making revealed great potential to discriminate patients with fatal outcomes from a mild course of disease (AUC 0.938, 95% CI 0.89 to 0.97) and the need for intensive care treatment (AUC 0.801, 95% CI 0.77 to 0.83).
Purpose: To assess and correlate pulmonary involvement and outcome of SARS-CoV-2 pneumonia with the degree of coronary plaque burden based on the CAC-DRS classification (Coronary Artery Calcium Data and Reporting System).
Methods: This retrospective study included 142 patients with confirmed SARS-CoV-2 pneumonia (58 ± 16 years; 57 women) who underwent non-contrast CT between January 2020 and August 2021 and were followed up for 129 ± 72 days. One experienced blinded radiologist analyzed CT series for the presence and extent of calcified plaque burden according to the visual and quantitative HU-based CAC-DRS Score. Pulmonary involvement was automatically evaluated with a dedicated software prototype by another two experienced radiologists and expressed as Opacity Score.
Results: CAC-DRS Scores derived from visual and quantitative image evaluation correlated well with the Opacity Score (r=0.81, 95% CI 0.76-0.86, and r=0.83, 95% CI 0.77-0.89, respectively; p<0.0001) with higher correlation in severe than in mild stage SARS-CoV-2 pneumonia (p<0.0001). Combined, CAC-DRS and Opacity Scores revealed great potential to discriminate fatal outcomes from a mild course of disease (AUC 0.938, 95% CI 0.89-0.97), and the need for intensive care treatment (AUC 0.801, 95% CI 0.77-0.83). Visual and quantitative CAC-DRS Scores provided independent prognostic information on all-cause mortality (p=0.0016 and p<0.0001, respectively), both in univariate and multivariate analysis.
Conclusions: Coronary plaque burden is strongly correlated to pulmonary involvement, adverse outcome, and death due to respiratory failure in patients with SARS-CoV-2 pneumonia, offering great potential to identify individuals at high risk.
Background: Dual-energy CT (DECT)-derived bone mineral density (BMD) of the distal radius and other CT-derived metrics related to bone health have been suggested for opportunistic osteoporosis screening and risk evaluation for sustaining distal radius fractures (DRFs).
Methods: The distal radius of patients who underwent DECT between 01/2016 and 08/2021 was retrospectively analyzed. Cortical Hounsfield Unit (HU), trabecular HU, cortical thickness, and DECT-based BMD were acquired from a non-fractured, metaphyseal area in all examinations. Receiver-operating characteristic (ROC) analysis was conducted to determine the area under the curve (AUC) values for predicting DRFs based on DECT-derived BMD, HU values, and cortical thickness. Logistic regression models were then employed to assess the associations of these parameters with the occurrence of DRFs.
Results: In this study, 263 patients (median age: 52 years; interquartile range: 36–64; 132 women; 192 fractures) were included. ROC curve analysis revealed a higher area under the curve (AUC) value for DECT-derived BMD compared to cortical HU, trabecular HU, and cortical thickness (0.91 vs. 0.61, 0.64, and 0.69, respectively; p <.001). Logistic regression models confirmed the association between lower DECT-derived BMD and the occurrence of DRFs (Odds Ratio, 0.83; p <.001); however, no influence was observed for cortical HU, trabecular HU, or cortical thickness.
Conclusions: DECT can be used to assess the BMD of the distal radius without dedicated equipment such as calibration phantoms to increase the detection rates of osteoporosis and stratify the individual risk to sustain DRFs. In contrast, assessing HU-based values and cortical thickness does not provide clinical benefit.
Rationale and Objectives: Bone non-union is a serious complication of distal radius fractures (DRF) that can result in functional limitations and persistent pain. However, no accepted method has been established to identify patients at risk of developing bone non-union yet. This study aimed to compare various CT-derived metrics for bone mineral density (BMD) assessment to identify predictive values for the development of bone non-union.
Materials and Methods: CT images of 192 patients with DRFs who underwent unenhanced dual-energy CT (DECT) of the distal radius between 03/2016 and 12/2020 were retrospectively identified. Available follow-up imaging and medical health records were evaluated to determine the occurrence of bone non-union. DECT-based BMD, trabecular Hounsfield unit (HU), cortical HU and cortical thickness ratio were measured in normalized non-fractured segments of the distal radius.
Results: Patients who developed bone non-union were significantly older (median age 72 years vs. 54 years) and had a significantly lower DECT-based BMD (median 68.1 mg/cm3 vs. 94.6 mg/cm3, p < 0.001). Other metrics (cortical thickness ratio, cortical HU, trabecular HU) showed no significant differences. ROC and PR curve analyses confirmed the highest diagnostic accuracy for DECT-based BMD with an area under the curve (AUC) of 0.83 for the ROC curve and an AUC of 0.46 for the PR curve. In logistic regression models, DECT-based BMD was the sole metric significantly associated with bone non-union.
Conclusion: DECT-derived metrics can accurately predict bone non-union in patients who sustained DRF. The diagnostic performance of DECT-based BMD is superior to that of HU-based metrics and cortical thickness ratio.
Highlights
• Piriform cortex and amgydala can be separated based on their distinct structural connectivity.
• Similar to histological findings, the connectivity of the piriform cortex suggests posterior frontal and temporal subregions.
• Subregions of the piriform cortex have distinct connectivity profiles.
• Anterior PC extended into ventrotemporal PC posteriorly, which has not been described before, requiring further investigation.
• All parcellations were made publicly available.
Abstract
The anatomy of the human piriform cortex (PC) is poorly understood. We used a bimodal connectivity-based-parcellation approach to investigate subregions of the PC and its connectional differentiation from the amygdala.
One hundred (55 % female) genetically unrelated subjects from the Human Connectome Project were included. A region of interest (ROI) was delineated bilaterally covering PC and amygdala, and functional and structural connectivity of this ROI with the whole gray matter was computed. Spectral clustering was performed to obtain bilateral parcellations at granularities of k = 2–10 clusters and combined bimodal parcellations were computed. Validity of parcellations was assessed via their mean individual-to-group similarity per adjusted rand index (ARI).
Individual-to-group similarity was higher than chance in both modalities and in all clustering solutions. The amygdala was clearly distinguished from PC in structural parcellations, and olfactory amygdala was connectionally more similar to amygdala than to PC. At higher granularities, an anterior and ventrotemporal and a posterior frontal cluster emerged within PC, as well as an additional temporal cluster at their boundary. Functional parcellations also showed a frontal piriform cluster, and similar temporal clusters were observed with less consistency. Results from bimodal parcellations were similar to the structural parcellations. Consistent results were obtained in a validation cohort.
Distinction of the human PC from the amygdala, including its olfactory subregions, is possible based on its structural connectivity alone. The canonical fronto-temporal boundary within PC was reproduced in both modalities and with consistency. All obtained parcellations are freely available.
Purpose: To describe a novel surgical technique of a combined implantation of an artificial iris and a scleral fixated intraocular lens (IOL) using flanged IOL haptics (“Yamane” technique).
Observations: The suturelessly implanted artificial iris-IOL-sandwich was stable with good functional as well as aesthetic results. However, our case showed a postoperative intraocular pressure rise.
Conclusions: The presented case demonstrates that a visual as well as cosmetical rehabilitation seems to be possible even after severe, penetrating ocular trauma with profound iris defects.
Importance: The sutureless IOL scleral fixation technique can also be used in combination with a sutureless artificial iris implantation. Further studies are needed to evaluate the long-term safety profile and rates of postoperative complications.
Purpose: The IC-8® Apthera™ (AcuFocus Inc.™, Irvine, California, USA) is the first small aperture intraocular lens (IOL) to receive FDA approval for presbyopia correction in the summer of 2022. It is a single-piece hydrophobic acrylic monofocal lens, which is placed in the capsular bag. In its center it carries a black circular mask (FilterRing™) with a diameter of 3.23 mm consisting of polyvinylidene fluoride and carbon black nanoparticles. In the center of this mask sits a 1.36 mm wide aperture. Thanks to this pinhole effect the IC-8® serves as an extended-depth-of-focus (EDOF) IOL and can be used in presbyopia correction.
This report describes the case of a patient with an IC-8® implant who underwent Nd:YAG laser capsulotomy for posterior capsule opacification (PCO). The post laser checkup showed a dark central optical change within the IOL and the patient described optical phenomena as well as blurred central vision, which is why he received IOL exchange. The explanted IC-8® was sent to the Intermountain Ocular Research Center at the University of Utah for further analysis.
Observations: A 56-year-old male underwent cataract surgery with implantation of a non-diffractive EDOF-IOL on the right and the IC-8® small aperture IOL on the left eye. On the left eye, the patient had received penetrating keratoplasty seven years prior to the cataract operation due to posttraumatic corneal scarring. The early checkups after cataract surgery showed a corrected distance visual acuity (CDVA) in the left eye of +0.1 logMAR in the first month. About 5 months after the operation, PCO was first described on the left eye leading to a decrease in visual acuity to +0.4 logMAR (CDVA). Due to PCO, Nd:YAG laser capsulotomy was conducted 5 months after the cataract operation on the left eye. 12 shots were applied at 2.7 mJ. The following appointments showed a continuously reduced visual acuity of +1.3 logMAR (uncorrected) on the left eye and the patient described blurry and ‘swirled’ central vision. By slightly tilting his head and thus not using the center of his optic axis, he would be able to see sharper. Slit lamp examination showed a small optical change inside the IC-8® IOL not resembling a pit but believed to be a small pocket of air. Due to the ongoing symptoms as well as the reduced VA, the seemingly damaged small aperture IOL was exchanged for a three-piece hydrophobic acrylic monofocal lens, which was also placed in the posterior chamber. The explanted IC-8® was sent to the Intermountain Ocular Research Center at the University of Utah for further analysis. Results from gross and light microscopic analysis showed that the change caused by the Nd:YAG laser application consisted of a localized optical area containing carbon black nanoparticles used for the circular mask within the IOL.
Conclusions and importance: When dealing with PCO and performing Nd:YAG laser capsulotomy in eyes with an IC-8® IOL implant, the laser shots should be applied either inside the aperture or outside of the black circular mask of the IOL. Otherwise, the Nd:YAG laser can lead to bursts of carbon nanoparticles within the IOL which may cause optical phenomena as well as decreased visual acuity possibly resulting in an IOL exchange.
Ferroptosis is a regulated form of cell death which is considered an oxidative iron-dependent process. The lipid hydroperoxidase glutathione peroxidase 4 prevents the iron (Fe2+)-dependent formation of toxic lipid reactive oxygen species. While emerging evidence indicates that inhibition of glutathione peroxidase 4 as a hallmark of ferroptosis in many cancer cell lines, the involvement of this biochemical pathway in neuronal death remains largely unclear. Here, we investigate, first whether the ferroptosis key players are involved in the neuronal cell death induced by erastin. The second objective was to examine whether there is a cross talk between ferroptosis and autophagy. The third main was to address neuron response to erastin, with a special focus on ferritin and nuclear receptor coactivator 4-mediated ferritinophagy. To test this in neurons, erastin (0.5–8 µM) was applied to hippocampal HT22 neurons for 16 hours. In addition, cells were cultured with the autophagy inhibitor, 3-methyladenin (10 mM) and/or ferroptosis inhibitors, ferrostatin 1 (10–20 µM) or deferoxamine (10–200 µM) before exposure to erastin. In this study, we demonstrated by immunofluorescence and western blot analysis, that erastin downregulates dramatically the expression of glutathione peroxidase 4, the sodium-independent cystine-glutamate antiporter and nuclear receptor coactivator 4. The protein levels of ferritin and mitochondrial ferritin in HT22 hippocampal neurons did not remarkably change following erastin treatment. In addition, we demonstrated that not only the ferroptosis inhibitor, ferrostatin1/deferoxamine abrogated the ferroptotic cell death induced by erastin in hippocampal HT22 neurons, but also the potent autophagy inhibitor, 3-methyladenin. We conclude that (1) erastin-induced ferroptosis in hippocampal HT22 neurons, despite reduced nuclear receptor coactivator 4 levels, (2) that either nuclear receptor coactivator 4-mediated ferritinophagy does not occur or is of secondary importance in this model, (3) that ferroptosis seems to share some features of the autophagic cell death process.
In the basal, proliferative layer of healthy skin, the mTOR complex 1 (mTORC1) is activated, thus regulating proliferation while preventing differentiation. When cells leave the proliferative, basal compartment, mTORC1 signaling is turned off, which allows differentiation. Under inflammatory conditions, this switch is hijacked by cytokines and prevents proper differentiation. It is currently unknown how mTORC1 is regulated to mediate these effects on keratinocyte differentiation. In other tissues, mTORC1 activity is controlled through various pathways via the tuberous sclerosis complex (TSC). Thus, we investigated whether the TS complex is regulated by proinflammatory cytokines and contributes to the pathogenesis of psoriasis. TNF-α as well as IL-1β induced the phosphorylation of TSC2, especially on S939 via the PI3-K/AKT and MAPK pathway. Surprisingly, increased TSC2 phosphorylation could not be detected in psoriasis patients. Instead, TSC2 was strongly downregulated in lesional psoriatic skin compared to non-lesional skin of the same patients or healthy skin. In vitro inflammatory cytokines induced dissociation of TSC2 from the lysosome, followed by destabilization of the TS complex and degradation. Thus, we assume that in psoriasis, inflammatory cytokines induce strong TSC2 phosphorylation, which in turn leads to its degradation. Consequently, chronic mTORC1 activity impairs ordered keratinocyte differentiation and contributes to the phenotypical changes seen in the psoriatic epidermis.
The culture of primary intestinal epithelia cells is not possible in a normal culture system. In 2009 a three-dimensional culture system of intestinal stem cells was established that shows many of the physiological features of the small intestine, such as crypt-villus structure, stem cell niche and all types of differentiated intestinal epithelial cells. These enteroids can be used to analyze biology of intestinal stem cells, gut homeostasis and the development of diseases. They also give the possibility to reduce animal numbers, as enteroids can be cryo-conserved and cultivated for many passages. To investigate the influence of genes such as NADPH oxidases on the gut homeostasis, transgenic approached are the method of choice. The generation of enteroids from knockout mice allows real-time observations of knockout effects. Often conditional knockout or overexpression strategies using inducible Cre recombinase are applied to avoid effects of adaption to the knockout. However, the Cre recombinase has many known caveats from unspecific binding and its endonuclease activity. In this study, we show that although NADPH oxidases are important for in vivo differentiation and proliferation of the intestine, their expression is drastically reduced in the organoid system. Activation of Cre recombinase by 4-hydroxy tamoxifen in freshly isolated enteroids, independently of floxed genes, leads to decreased diameter of organoids. This effect is concentration-dependent and is caused by reduced cell proliferation and induction of apoptosis and DNA damage. In contrast, constitutive expression of Cre has no impact on the enteroids. Therefore, reduction of tamoxifen concentration and treatment duration should be carefully titrated, and appropriate controls are necessary.
Purpose
To assess the diagnostic value of different imaging modalities in distinguishing systemic vasculitis from other internal and immunological diseases.
Methods
This retrospective study included 134 patients with suspected vasculitis who underwent ultrasound, magnetic resonance imaging (MRI), or 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) between 01/2010 and 01/2019, finally consisting of 70 individuals with vasculitis. The main study parameter was the confirmation of the diagnosis using one of the three different imaging modalities, with the adjudicated clinical and histopathological diagnosis as the gold standard. A secondary parameter was the morphological appearance of the vessel affected by vasculitis.
Results
Patients with systemic vasculitis had myriad clinical manifestations with joint pain as the most common symptom. We found significant correlations between different imaging findings suggestive of vasculitis and the final adjudicated clinical diagnosis. In this context, on MRI, vessel wall thickening, edema, and diameter differed significantly between vasculitis and non-vasculitis groups (p < 0.05). Ultrasound revealed different findings that may serve as red flags in identifying patients with vasculitis, such as vascular occlusion or halo sign (p = 0.02 vs. non-vasculitis group). Interestingly, comparing maximal standardized uptake values from PET/CT examinations with vessel wall thickening or vessel diameter did not result in significant differences (p > 0.05).
Conclusions
We observed significant correlations between different imaging findings suggestive of vasculitis on ultrasound or MRI and the final adjudicated diagnosis. While ultrasound and MRI were considered suitable imaging methods for detecting and discriminating typical vascular changes, 18F-FDG PET/CT requires careful timing and patient selection given its moderate diagnostic accuracy.
Purpose:
The purpose of the study was to provide a consensus definition of the infrarenal sealing zone and develop an algorithm to determine when and if adjunctive procedure(s) or reintervention should be considered in managing patients undergoing endovascular aortic repair (EVAR) for infrarenal abdominal aortic aneurysm (AAA).
Methods:
A European Advisory Board (AB), made up of 11 vascular surgeons with expertise in EVAR for AAA, was assembled to share their opinion regarding the definition of preoperative and postoperative infrarenal sealing zone. Information on their current clinical practice and level of agreement on proposed reintervention paths was used to develop an algorithm. The process included 2 virtual meetings and 2 rounds of online surveys completed by the AB (Delphi method). Consensus was defined as reached when ≥ 8 of 11 (73%) respondents agreed or were neutral.
Results:
The AB reached complete consensus on definitions and measurement of the pre-EVAR target anticipated sealing zone (TASZ) and the post-EVAR real achieved sealing zone (RASZ), namely, the shortest length between the proximal and distal reference points as defined by the AB, in case of patients with challenging anatomies. Also, agreement was achieved on a list of 4 anatomic parameters and 3 prosthesis-/procedure-related parameters, considered to have the most significant impact on preoperative and postoperative sealing zones. Furthermore, the agreement was reached that in the presence of visible neck-related complications, both adjunctive procedure(s) and reintervention should be contemplated (100% consensus). In addition, adjunctive procedure(s) or reintervention can be considered in the following cases (% consensus): insufficient sealing zone on completion imaging (91%) or on the first postoperative computed tomography (CT) scan (91%), suboptimal sealing zone on completion imaging (73%) or postoperative CT scan (82%), and negative evolution of the actual sealing zone over time (91%), even in the absence of visible complications.
Conclusions:
AB members agreed on definitions of the pre- and post-EVAR infrarenal sealing zone, as well as factors of influence. Furthermore, a clinical decision algorithm was proposed to determine the timing and necessity of adjunctive procedure(s) and reinterventions.
Background
Musclin is an activity‐stimulated and cardioprotective myokine that attenuates pathological cardiac remodeling. Musclin deficiency, in turn, results in reduced physical endurance. The aim of this study was to assess the prognostic value of circulating musclin as a novel, putative biomarker to identify patients undergoing transcatheter aortic valve implantation (TAVI) who are at a higher risk of death.
Methods and Results
In this study, we measured systemic musclin levels in 368 patients undergoing TAVI who were at low to intermediate clinical risk (median EuroSCORE [European System for Cardiac Operative Risk Evaluation] II: 3.5; quartile 1–quartile, 2.2%–5.3%), whereby 209 (56.8%) patients were at low and 159 (43.2%) were at intermediate risk. Median preprocedural musclin levels were 2.7 ng/mL (quartile 1–quartile 3, 1.5–4.6 ng/mL). Musclin levels were dichotomized in low (<2.862 ng/mL, n=199 [54.1%]) or high (≥ 2.862 ng/mL, n=169 [45.9%]) groups using cutoff values determined by classification and regression tree analysis. The primary end point was 1‐year overall survival. Patients with low circulating musclin levels exhibited a significantly higher prevalence of frailty, low albumin values, hypertension, and history of stroke as well as higher N‐terminal pro‐B‐type natriuretic peptide. Low musclin levels significantly predicted risk of death in univariable (hazard ratio, 1.81; 95% CI, 1.00–3.53 [P=0.049]) and multivariable (adjusted hazard ratio, 2.45; 95% CI, 1.06–5.69 [P=0.037]) Cox regression analyses. Additionally, low musclin levels in combination with conventional EuroSCORE II suggested improved risk stratification in patients undergoing TAVI who were at low to intermediate clinical risk into subgroups with reduced 1‐year survival rates by log‐rank test (P for trend=0.003).
Conclusions
Circulating musclin is an independent predictor of 1‐year overall survival in patients undergoing TAVI. Combined with EuroSCORE II, circulating musclin might help to improve prediction of mortality in patients undergoing TAVI who are at low to intermediate clinical risk.
Infection with the SARS (Severe Acute Respiratory Syndrome)-associated coronavirus results in respiratory failure probably by immunological mechanisms in 10% of patients. Laboratory markers that predict subsequent respiratory failure would therefore be useful in patient management.
We describe the clinical course, hematologic parameters, lymphocyte subpopulations and markers of inflammation in two patients with SARS, i.e., one man with diabetes mellitus and one pregnant woman, infected by the same viral isolate.
The patient with underlying diabetes mellitus developed respiratory failure after admission in the second week of the illness while the second patient developed only a mild disease without respiratory failure. Subsequent respiratory dysfunction was associated with lown umbers of Natural Killer (NK) cells at presentation and elevated CRP levels during the illness.
NK cells and CRP levels at the end of the first week of the disease might be related to subsequent respiratory dysfunction and may link underlying conditions to disease severity.
The transcription factor hypoxia-inducible factor 1 (HIF1) is an important driver of cancer and is therefore an attractive drug target. Acriflavine (ACF) has been suggested to inhibit HIF1, but its mechanism of action is unknown. Here we investigated the interaction of ACF with DNA and long non-coding RNAs (lncRNAs) and its function in human endothelial cells. ACF promoted apoptosis and reduced proliferation, network formation, and angiogenic capacity. It also induced changes in gene expression, as determined by RNA sequencing (RNA-seq), which could not be attributed to specific inhibition of HIF1. A similar response was observed in murine lung endothelial cells. Although ACF increased and decreased a similar number of protein-coding genes, lncRNAs were preferentially upregulated under normoxic and hypoxic conditions. An assay for transposase accessibility with subsequent DNA sequencing (ATAC-seq) demonstrated that ACF induced strong changes in chromatin accessibility at lncRNA promoters. Immunofluorescence showed displacement of DNA:RNA hybrids. Such effects might be due to ACF-mediated topoisomerase inhibition, which was indeed the case, as reflected by DNA unwinding assays. Comparison with other acridine derivatives and topoisomerase inhibitors suggested that the specific function of ACF is an effect of acridinium-class compounds. This study demonstrates that ACF inhibits topoisomerases rather than HIF specifically and that it elicits a unique expression response of lncRNAs.
Objectives
To identify the main problem areas in the applicability of the current TNM staging system (8th ed.) for the radiological staging and reporting of rectal cancer and provide practice recommendations on how to handle them.
Methods
A global case-based online survey was conducted including 41 image-based rectal cancer cases focusing on various items included in the TNM system. Cases reaching < 80% agreement among survey respondents were identified as problem areas and discussed among an international expert panel, including 5 radiologists, 6 colorectal surgeons, 4 radiation oncologists, and 3 pathologists.
Results
Three hundred twenty-one respondents (from 32 countries) completed the survey. Sixteen problem areas were identified, related to cT staging in low-rectal cancers, definitions for cT4b and cM1a disease, definitions for mesorectal fascia (MRF) involvement, evaluation of lymph nodes versus tumor deposits, and staging of lateral lymph nodes. The expert panel recommended strategies on how to handle these, including advice on cT-stage categorization in case of involvement of different layers of the anal canal, specifications on which structures to include in the definition of cT4b disease, how to define MRF involvement by the primary tumor and other tumor-bearing structures, how to differentiate and report lymph nodes and tumor deposits on MRI, and how to anatomically localize and stage lateral lymph nodes.
Conclusions
The recommendations derived from this global survey and expert panel discussion may serve as a practice guide and support tool for radiologists (and other clinicians) involved in the staging of rectal cancer and may contribute to improved consistency in radiological staging and reporting.
While in large clinical laboratories the implementation of total laboratory automation is continuously proceeding, this concept is mostly not suitable for small- and middle-sized laboratories or for testing laboratories of blood donation services due to costs and required space. For these facilities, however, a rational level of automation can be achieved by the installation of stand-alone work cells for pre-analytical and selected analytical processes. In this review, the features of some automated pre-analytical sample processing systems and automated systems for the serological testing for infectious diseases are described exemplarily and compared with each other. The major advantages of automated systems, compared to a solely manual workflow, are described. Essential factors which have to be considered for making the choice for an appropriate automated system are pointed out.
Purpose: Discordance between pre-operative biopsy and final pathology for Upper Tract Urothelial Carcinoma (UTUC) is high and optimal management remains controversial. The aim of this study is to evaluate the accuracy of pre-operative biopsy, to identify prognostic factors and to evaluate the effect of adjuvant chemotherapy on survival and oncologic outcome in UTUC.
Methods: We analyzed records of patients receiving surgical treatment for UTUC. Pathology of pre-operative biopsy was compared to surgical specimen. We used Kaplan-Meier method to estimate survival probabilities and Cox's proportional hazards models to estimate the association between covariates and event times. Primary endpoint was overall survival (OS). A matched-pair analysis was performed to evaluate the effect of adjuvant chemotherapy.
Results: 151 patients underwent surgical treatment (28% open, 36% laparoscopic, 17% robotic radical nephroureterectomy; 14% segmental ureteral resections and 5% palliative nephrectomy) for UTUC and were included in the analysis. Upstaging from <pT1 in endoscopic biopsy to ≥pT1 in final pathology occurred in 61% of patients and upgrading from low-grade to high-grade occurred in 30% of patients. Five-year OS was 59.5%. In the univariate Cox-regression model pathological stage, grade, lymphovascular invasion and positive surgical margins were associated with OS. Matched pair analysis for stage (<pT3; ≥pT3; pN+) and age revealed a significant survival benefit for adjuvant chemotherapy (HR 0.40, 0.14–0.77, p < 0.018) in this cohort.
Conclusion: UTUC is often underestimated in pre-operative biopsy, and it is associated with significant mortality. Pathological stage and grade, lymphovascular invasion and lymph node metastases are predictors of oncologic outcome and survival.
Congenital diaphragmatic hernia (CDH) is a relatively common and life-threatening birth defect, characterized by an abnormal opening in the primordial diaphragm that interferes with normal lung development. As a result, CDH is accompanied by immature and hypoplastic lungs, being the leading cause of morbidity and mortality in patients with this condition. In recent decades, various animal models have contributed novel insights into the pathogenic mechanisms underlying CDH and associated pulmonary hypoplasia. In particular, the generation of genetically modified mouse models, which show both diaphragm and lung abnormalities, has resulted in the discovery of multiple genes and signaling pathways involved in the pathogenesis of CDH. This article aims to offer an up-to-date overview on CDH-implicated transcription factors, molecules regulating cell migration and signal transduction as well as components contributing to the formation of extracellular matrix, whilst also discussing the significance of these genetic models for studying altered lung development with regard to the human situation.
Background
Photochemical internalization (PCI) is a novel technology for light-induced enhancement of the local therapeutic effect of cancer drugs, utilizing a specially designed photosensitizing molecule (fimaporfin). The photosensitizing molecules are trapped in endosomes along with macromolecules or drugs. Photoactivation of fimaporfin disrupts the endosomal membranes so that drug molecules are released from endosomes inside cells and can reach their therapeutic target in the cell cytosol or nucleus. Compared with photodynamic therapy, the main cytotoxic effect with PCI is disruption of the endosomal membrane resulting in delivery of chemotherapy drug, and not to the photochemical reactions per se. In this study we investigated the effect of PCI with gemcitabine in patients with inoperable perihilar cholangiocarcinoma (CCA).
Methods
The in vitro cytotoxic effect of PCI with gemcitabine was studied on two CCA-derived cell lines. In a fimaporfin dose-escalation phase I clinical study, we administered PCI with gemcitabine in patients with perihilar CCA (n = 16) to establish a safe and tolerable fimaporfin dose and to get early signals of efficacy. The patients enrolled in the study had tumors in which the whole length of the tumor could be illuminated from the inside of the bile duct, using an optical fiber inserted via an endoscope (Fig. 1). Fimaporfin was administered intravenously at day 0; gemcitabine (i.v.) and intraluminal biliary endoscopic laser light application on day 4; followed by standard gemcitabine/cisplatin chemotherapy.
Results
Preclinical experiments showed that PCI enhanced the effect of gemcitabine. In patients with CCA, PCI with gemcitabine was well tolerated with no dose-limiting toxicities, and no unexpected safety signals. Disease control was achieved in 10 of 11 evaluable patients, with a clearly superior effect in the two highest dose groups. The objective response rate (ORR) was 42%, including two complete responses, while ORR at the highest dose was 60%. Progression-free survival at 6 months was 75%, and median overall survival (mOS) was 15.4 months, with 22.8 months at the highest fimaporfin dose.
Conclusion
Photochemical internalization with gemcitabine was found to be safe and resulted in encouraging response and survival rates in patients with unresectable perihilar CCA.
The long-term effect of protection by two doses of SARS-CoV-2 vaccination in patients receiving chronic intermittent hemodialysis (CIHD) is an urging question. We investigated the humoral and cellular immune response of 42 CIHD patients who had received two doses of SARS-CoV-2 vaccine, and again after a booster vaccine with mRNA-1273 six months later. We measured antibody levels and SARS-CoV-2-specific surrogate neutralizing antibodies (SNA). Functional T cell immune response to vaccination was assessed by quantifying interferon-γ (IFN-γ) and IL-2 secreting T cells specific for SARS-CoV-2 using an ELISpot assay. Our data reveal a moderate immune response after the second dose of vaccination, with significantly decreasing SARS-CoV-2-specific antibody levels and less than half of the study group showed neutralizing antibodies six months afterwards. Booster vaccines increased the humoral response dramatically and led to a response rate of 89.2% for antibody levels and a response rate of 94.6% for SNA. Measurement in a no response/low response (NR/LR) subgroup of our cohort, which differed from the whole group in age and rate of immunosuppressive drugs, indicated failure of a corresponding T cell response after the booster vaccine. We strongly argue in favor of a regular testing of surrogate neutralizing antibodies and consecutive booster vaccinations for CIHD patients to provide a stronger and persistent immunity.
Abstract
The co-occurrence of insulin resistance (IR)-related metabolic conditions with neuropsychiatric disorders is a complex public health challenge. Evidence of the genetic links between these phenotypes is emerging, but little is currently known about the genomic regions and biological functions that are involved. To address this, we performed Local Analysis of [co]Variant Association (LAVA) using large-scale (N=9,725-933,970) genome-wide association studies (GWASs) results for three IR-related conditions (type 2 diabetes mellitus, obesity, and metabolic syndrome) and nine neuropsychiatric disorders. Subsequently, positional and expression quantitative trait locus (eQTL)-based gene mapping and downstream functional genomic analyses were performed on the significant loci. Patterns of negative and positive local genetic correlations (|rg|=0.21-1, pFDR<0.05) were identified at 109 unique genomic regions across all phenotype pairs. Local correlations emerged even in the absence of global genetic correlations between IR-related conditions and Alzheimer’s disease, bipolar disorder, and Tourette’s syndrome. Genes mapped to the correlated regions showed enrichment in biological pathways integral to immune-inflammatory function, vesicle trafficking, insulin signalling, oxygen transport, and lipid metabolism. Colocalisation analyses further prioritised 10 genetically correlated regions for likely harbouring shared causal variants, displaying high deleterious or regulatory potential. These variants were found within or in close proximity to genes, such as SLC39A8 and HLA-DRB1, that can be targeted by supplements and already known drugs, including omega-3/6 fatty acids, immunomodulatory, antihypertensive, and cholesterol-lowering drugs. Overall, our findings underscore the complex genetic landscape of IR-neuropsychiatric multimorbidity, advocating for an integrated disease model and offering novel insights for research and treatment strategies in this domain.
Highlights
Local genetic correlations found even in the absence of global correlations.
Both positive and negative local correlations found for IR-neuropsychiatric pairs.
Enrichment for immune, and insulin signalling pathways, among others.
Pinpointed shared likely causal variants within 10 genomic regions.
Identified therapeutic targets, e.g., SLC39A8 and HLA-DRB1, for drug repurposing.
Background: For rheumatoid arthritis (RA), the treat-to-target concept suggests attaining remission or at least low disease activity (LDA) after 12 weeks.
Objectives: This German, prospective, multicenter, non-interventional study aimed to determine the proportion of patients with RA who achieved their treat-to-target aim after 12 and 24 weeks of etanercept (ETN) treatment in a real-life setting, as opposed to patients achieving their therapeutic target at a later timepoint (week 36 or 52).
Methods: A total of 824 adults with a confirmed diagnosis of RA without prior ETN treatment were included. Remission and LDA were defined as DAS28 < 2.6 and DAS28 ≤ 3.2, respectively.
Results: The proportion of patients achieving remission was 24% at week 12 and 31% at week 24. The proportion of patients achieving LDA was 39% at week 12 and 45% at week 24. The proportion of patients achieving remission or LDA further increased beyond week 24 up to week 52. Improvement in pain and reduction in concomitant glucocorticoid treatment were observed. Improvements in patient-reported outcomes were also seen in patients who did not reach remission or LDA. No new safety signals were detected.
Conclusions: A considerable proportion of patients with RA attained the target of remission or LDA after 12 weeks of ETN treatment. Even beyond that timepoint, the proportion of patients achieving treatment targets continued to increase up to week 52.
Trial Registration
ClinicalTrials.gov Identifier: NCT02486302.
Plain Language Summary
Physicians measure response to treatment of rheumatoid arthritis using a disease activity score (DAS28). People with a DAS28 of less than 2.6 have very few to no symptoms (also called remission). People with a DAS28 of 3.2 or less, called low disease activity, may experience mild symptoms. When people do not respond to treatment after 12 weeks, it is usually recommended to prescribe a different treatment. Researchers do not know how many people who do not respond after 12 weeks would respond if treatment were continued. A total of 824 German people with rheumatoid arthritis who received a drug called etanercept for up to 52 weeks took part in this study. Researchers wanted to know how many people had remission or low disease activity after 12 weeks and 24 weeks of treatment.
After 12 weeks, 24 in 100 people had remission; this increased to 31 in 100 people after 24 weeks. Thirty-nine in 100 people had low disease activity after 12 weeks; this increased to 45 in 100 people after 24 weeks. The number of people with remission or low disease activity increased with longer treatment (up to 52 weeks). People needed less additional treatment with a type of drug called glucocorticoids. The people in this study experienced side effects that were similar to those reported by people who took etanercept in previous studies.
The researchers concluded that a considerable proportion of people responded to treatment with etanercept after 12 weeks. This proportion increased when treatment was continued for longer than 12 weeks.
Porous tantalum trabecular metal biomaterial has a similar structure to trabecular bone, and was recently added to titanium dental implants as a surface enhancement. The purpose of this prospective pilot study was to describe 5-year survival results and crestal bone level changes around immediately-provisionalized Trabecular Metal Dental Implants. Eligible patients were adults in need of ≥1 implants in the posterior jaw. A non-occluding single acrylic provisional crown was in place for up to 14 days before final restoration. Clinical evaluations with radiographs were conducted at each follow-up visit (1 month, 3 months, 6 months, and 1 to 5 years). The primary endpoint was implant survival, characterized using the Kaplan-Meier method. The secondary endpoint was changes in crestal bone level, evaluated using a paired t-test to compare mean crestal bone levels between the baseline, 6-month, and annual follow-up values. In total, 30 patients (37 implants) were treated. Mean patient age was 45.5 years, and 63% were female. There was one implant failure; cumulative survival at 5 years was 97.2%. After the initial bone loss of 0.40 mm in the first 6 months, there were no statistically significant changes in crestal bone level over time up to 5 years of follow-up.
Objective: Liver stiffness measurement (LSM) is a tool used to screen for significant fibrosis and portal hypertension. The aim of this retrospective multicentre study was to develop an easy tool using LSM for clinical outcomes in advanced chronic liver disease (ACLD) patients.
Design: This international multicentre cohort study included a derivation ACLD patient cohort with valid two-dimensional shear wave elastography (2D-SWE) results. Clinical and laboratory parameters at baseline and during follow-up were recorded. LSM by transient elastography (TE) was also recorded if available. The primary outcome was overall mortality. The secondary outcome was the development of first/further decompensation.
Results: After screening 2148 patients (16 centres), 1827 patients (55 years, 62.4% men) were included in the 2D-SWE cohort, with median liver SWE (L-SWE) 11.8 kPa and a model for end stage liver disease (MELD) score of 8. Combination of MELD score and L-SWE predict independently of mortality (AUC 0.8). L-SWE cut-off at ≥20 kPa combined with MELD ≥10 could stratify the risk of mortality and first/further decompensation in ACLD patients. The 2-year mortality and decompensation rates were 36.9% and 61.8%, respectively, in the 305 (18.3%) high-risk patients (with L-SWE ≥20 kPa and MELD ≥10), while in the 944 (56.6%) low-risk patients, these were 1.1% and 3.5%, respectively. Importantly, this M10LS20 algorithm was validated by TE-based LSM and in an additional cohort of 119 patients with valid point shear SWE-LSM.
Conclusion: The M10LS20 algorithm allows risk stratification of patients with ACLD. Patients with L-SWE ≥20 kPa and MELD ≥10 should be followed closely and receive intensified care, while patients with low risk may be managed at longer intervals.
Rationale: Studies have suggested mental health improvements following the use of the psychotropic plant concoction ayahuasca in non-clinical and clinical samples.
Objectives: The present observational study assessed depressive symptomatology in 20 clinically depressed patients (symptom score > 13 on the Beck’s Depression Inventory) before attendance of an ayahuasca ceremony and 1 month and 1 year after. Secondary measures included ratings of altered states of consciousness and ego dissolution during the ayahuasca ceremony as well as global measures of mindfulness, satisfaction with life, depression, anxiety, and stress.
Results: Twenty participants completed baseline and 1-day follow-up, 19 completed measures at 1-month follow-up, and 17 completed measures at 1-year follow-up. BDI scores reduced from baseline (M = 22.7) to all post-ceremony measures (Ms 11.45, 12.89, and 8.88, for 1-day, 1-month, and 1-year follow-up, respectively). After 1 day, 12/20 participants were in remission (BDI < 13). Remission rates after 1 month and 1 year were 13/19 and 12/17, respectively. Three participants remained mildly depressed (BDI 14–19) at the 1-month and 1-year follow-up. Two participants did not respond and remained at a moderate/severe level of depression at 1-year follow-up. Reductions on the secondary mental health measures and increases in mindfulness and satisfaction with life were found up to 1 year post-ceremony. Improvements in clinical depression and mental health correlated with levels of experienced ego dissolution and oceanic boundlessness during the ceremony up to 1 month after the ceremony. Engagement in additional mental health treatments or use of another psychedelic during study participation may have contributed to improved mental health ratings at 1-year follow-up.
Conclusion: Ayahuasca produces long-term mental health improvements in clinically depressed patients, which highlights its therapeutic potential.
Glecaprevir/pibrentasvir, a pangenotypic, direct-acting antiviral combination approved for chronic hepatitis C virus treatment, has limited real-world evidence supporting 8-week therapy in compensated cirrhosis. We investigated effectiveness and safety of 187 hepatitis C virus-infected, treatment-naïve, patients with compensated cirrhosis receiving 8-week glecaprevir/pibrentasvir therapy in the German Hepatitis C-Registry between 2 August 2017 and 1 January 2020. Sustained virologic response was 98.4% (127/129) in the per-protocol analysis (excluding patients lost to follow-up or who discontinued treatment due to compliance) and was 85.8% (127/148) in patients with data available in an intention-to-treat analysis. Nineteen patients were lost to follow-up; nine genotype 3 patients, nine nongenotype 3 patients and one mixed genotype patient. One patient relapsed, and one died, unrelated to treatment. Adverse events (>5%) were fatigue and headache. Two serious adverse events occurred; no adverse events resulted in drug discontinuation. An 8-week glecaprevir/pibrentasvir therapy was effective and well-tolerated in this real-world analysis.
Understanding how epigenetic variation in non-coding regions is involved in distal gene-expression regulation is an important problem. Regulatory regions can be associated to genes using large-scale datasets of epigenetic and expression data. However, for regions of complex epigenomic signals and enhancers that regulate many genes, it is difficult to understand these associations. We present StitchIt, an approach to dissect epigenetic variation in a gene-specific manner for the detection of regulatory elements (REMs) without relying on peak calls in individual samples. StitchIt segments epigenetic signal tracks over many samples to generate the location and the target genes of a REM simultaneously. We show that this approach leads to a more accurate and refined REM detection compared to standard methods even on heterogeneous datasets, which are challenging to model. Also, StitchIt REMs are highly enriched in experimentally determined chromatin interactions and expression quantitative trait loci. We validated several newly predicted REMs using CRISPR-Cas9 experiments, thereby demonstrating the reliability of StitchIt. StitchIt is able to dissect regulation in superenhancers and predicts thousands of putative REMs that go unnoticed using peak-based approaches suggesting that a large part of the regulome might be uncharted water.
Highlights
• Single nucleotide variants (SNVs) may affect transcription factor (TF) binding
• Fast statistical approach to assess significance of differential TF binding for SNVs
• Validate new approach on in vitro and in vivo TF binding assays
• Applications on GWAS SNVs and large eQTL studies illustrate utility
Summary
Non-coding variants located within regulatory elements may alter gene expression by modifying transcription factor (TF) binding sites, thereby leading to functional consequences. Different TF models are being used to assess the effect of DNA sequence variants, such as single nucleotide variants (SNVs). Often existing methods are slow and do not assess statistical significance of results. We investigated the distribution of absolute maximal differential TF binding scores for general computational models that affect TF binding. We find that a modified Laplace distribution can adequately approximate the empirical distributions. A benchmark on in vitro and in vivo datasets showed that our approach improves upon an existing method in terms of performance and speed. Applications on eQTLs and on a genome-wide association study illustrate the usefulness of our statistics by highlighting cell type-specific regulators and target genes. An implementation of our approach is freely available on GitHub and as bioconda package.
Purpose: To assess the diagnostic precision of three different workstations for measuring thoracic aortic aneurysms (TAAs) in vivo and ex vivo using either pre-interventional computed tomography angiography scans (CTA) or a specifically designed phantom model.
Methods: This retrospective study included 23 patients with confirmed TAA on routinely performed CTAs. In addition to phantom tube diameters, one experienced blinded radiologist evaluated the dimensions of TAAs on three different workstations in two separate rounds. Precision was assessed by calculating measurement errors. In addition, correlation analysis was performed using Pearson correlation.
Results: Measurements acquired at the Siemens workstation deviated by 3.54% (range, 2.78–4.03%; p = 0.14) from the true size, those at General Electric by 4.05% (range, 1.46–7.09%; p < 0.0001), and at TeraRecon by 4.86% (range, 3.22–6.45%; p < 0.0001). Accordingly, Siemens provided the most precise workstation at simultaneously most fluctuating values (scattering of 4.46%). TeraRecon had the smallest fluctuation (scattering of 2.83%), but the largest deviation from the true size of the phantom. The workstation from General Electric showed a scattering of 2.94%. The highest overall correlation between the 1st and 2nd rounds was observed with measurements from Siemens (r = 0.898), followed by TeraRecon (r = 0.799), and General Electric (r = 0.703). Repetition of measurements reduced processing times by 40% when using General Electric, by 20% with Siemens, and by 18% with TeraRecon.
Conclusions: In conclusion, all three workstations facilitated precise assessment of dimensions in the majority of cases at simultaneously high reproducibility, ensuring accurate pre-interventional planning of thoracic endovascular aortic repair.
Background: Opsoclonus-myoclonus syndrome (OMS) is a rare, immune-mediated neurological disorder. In adults, the pathogenesis can be idiopathic, post-infectious or paraneoplastic, the latter etiology belonging to the ever-expanding group of defined paraneoplastic neurological syndromes (PNS). In contrast to other phenotypes of PNS, OMS cannot be ascribed to a single pathogenic autoantibody. Here, we report the first detailed case of paraneoplastic, antibody-negative OMS occurring in association with a pancreatic neuroendocrine tumor (pNET).
Case presentation: A 33-year-old female presented with a two-week history of severe ataxia of stance and gait, dysarthria, head tremor, myoclonus of the extremities and opsoclonus. Her past medical history was notable for a metastatic pancreatic neuroendocrine tumor, and she was subsequently diagnosed with paraneoplastic opsoclonus-myoclonus syndrome. Further workup did not reveal a paraneoplastic autoantibody. She responded well to plasmapheresis, as she was refractory to the first-line therapy with corticosteroids.
Conclusions: This case expands current knowledge on tumors associated with paraneoplastic opsoclonus-myoclonus syndrome and the age group in which it can occur. It further adds evidence to the effectiveness of plasmapheresis in severe cases of opsoclonus-myoclonus syndrome with a lack of response to first-line therapy.
Structured management programs have been developed for single diseases but rarely for patients with multiple medications. We conducted a qualitative study to investigate the views of stakeholders on the development and implementation of a polypharmacy management program in Germany. Overall, we interviewed ten experts in the fields of health policy and clinical practice. Using content analysis, we identified inclusion criteria for the selection of suitable patients, the individual elements that should make up such a program, healthcare providers and stakeholders that should be involved, and factors that may support or hinder the program’s implementation. All stakeholders were well aware of polypharmacy-related risks and challenges, as well as the urgent need for change. Intervention strategies should address all levels of care and include all concerned patients, caregivers, healthcare providers and stakeholders, and involved parties should agree on a joint approach.
Objectives: To assess the impact of noise-optimised virtual monoenergetic imaging (VMI+) on image quality and diagnostic evaluation in abdominal dual-energy CT scans with impaired portal-venous contrast.
Methods: We screened 11,746 patients who underwent portal-venous abdominal dual-energy CT for cancer staging between 08/2014 and 11/2019 and identified those with poor portal-venous contrast.
Standard linearly-blended image series and VMI+ image series at 40, 50, and 60 keV were reconstructed. Signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) of abdominal organs and vascular structures were calculated. Image noise, image contrast and overall image quality were rated by three radiologists using 5-point Likert scale.
Results: 452 of 11,746 (4%) exams were poorly opacified. We excluded 190 cases due to incomplete datasets or multiple exams of the same patient with a final study group of 262. Highest CNR values in all abdominal organs (liver, 6.4 ± 3.0; kidney, 17.4 ± 7.5; spleen, 8.0 ± 3.5) and vascular structures (aorta, 16.0 ± 7.3; intrahepatic vein, 11.3 ± 4.7; portal vein, 15.5 ± 6.7) were measured at 40 keV VMI+ with significantly superior values compared to all other series. In subjective analysis, highest image contrast was seen at 40 keV VMI+ (4.8 ± 0.4), whereas overall image quality peaked at 50 keV VMI+ (4.2 ± 0.5) with significantly superior results compared to all other series (p < 0.001).
Conclusions: Image reconstruction using VMI+ algorithm at 50 keV significantly improves image contrast and image quality of originally poorly opacified abdominal CT scans and reduces the number of non-diagnostic scans.
Advances in knowledge: We validated the impact of VMI+ reconstructions in poorly attenuated DECT studies of the abdomen in a big data cohort.
Measurements of vertical velocity from vertically pointing Doppler lidars are used to derive the profiles of vertical velocity variance. Observations were taken during the FESSTVaL (Field Experiment on Submesoscale Spatio-Temporal Variability in Lindenberg) campaign during the warm seasons of 2020 and 2021. Normalized by the square of convective velocity scale, the average vertical velocity variance profile follows the universal profile of Lenschow et al. (1980), however, daily profiles still show a high day-to-day variability. We found that moisture transport and the content of moisture in the boundary layer could explain the remaining variability of the normalized vertical velocity variance. The magnitude of the normalized vertical velocity variance is highest on clear-sky days, and decreases as the relative humidity increase and surface latent heat flux decrease in cloud-topped and rainy days. This suggests that moisture content and moisture transport are limiting factors for the intensity of turbulence in the convective boundary layer. We also found that the intensity of turbulence decreases with an increase in boundary layer cloud fraction during FESSTVaL, while the latent heating in the cloud layer was not a relevant source of turbulence in this case. We conclude that a new vertical velocity scale has to be defined that would take into account the moist processes in the convective boundary layer.
Measurements of vertical velocity from vertically pointing Doppler lidars are used to derive the profiles of normalized vertical velocity variance. Observations were taken during the FESSTVaL (Field Experiment on Submesoscale Spatio-Temporal Variability in Lindenberg) campaign during the warm seasons of 2020 and 2021. Normalized by the square of the convective velocity scale, the average vertical velocity variance profile follows the universal profile of Lenschow et al. (1980). However, daily profiles still show a high day-to-day variability. We found that moisture transport and the content of moisture in the boundary layer could explain the remaining variability of the normalized vertical velocity variance. The magnitude of the normalized vertical velocity variance is highest on clear-sky days and decreases as the absolute humidity increases and surface latent heat flux decreases on cloud-topped days. This suggests that moisture content and moisture transport are limiting factors for the intensity of turbulence in the convective boundary layer. We also found that the intensity of turbulence decreases with an increase in the boundary layer cloud fraction during FESSTVaL, while the latent heating in the cloud layer was not a relevant source of turbulence in this case. We conclude that a new vertical velocity scale has to be defined that would take into account the moist processes in the convective boundary layer.
Background: In the Computer Tomography imaging, examinations for the diagnosis of lesions of the upper abdomen currently use water-soluble, iodinated, non-ionic contrast agents with low molecular weight. One possibility to reduce the time of the examination and X-ray exposure is to increase the injection rate. However, higher injections rates lead to increased hypersensitivity reactions and extravasation rates. Furthermore, cardiac pump function does not always allow for the transportation of such a large volume within one heartbeat. With a contrast agent of higher iodine concentration, the injection rate may be reduced without decreasing the iodine delivery rate while reducing the volume load of the heart.
Aim: to compare the performance and image quality of two injection protocols of contrast medium for multiphasic CT imaging of malignant hepatic lesions; one using Imeron 300 at an injection rate of 5 ml/ sec and the second using Imeron 400 at an injection rate of 3,7 ml/ sec, for multiphasic CT imaging of malignant hepatic lesions, in order to optimise the iodine concentration and injection rate of the contrast agent Imeron in the Multislice Spiral-CT of the upper abdomen.
Materials and methods: the current prospective, single centre, double-blinded, randomised and interindividual comparison study included 50 patients (29 males and 21 females) with a mean age of 63,3 years. Patients were randomised to one of the two injection protocols. Image evaluation included qualitative assessment (technical quality, presence of artefacts and overall contrast quality) and quantitative assessment (measuring the difference in HU between the lesion and the surrounding hepatic tissue). The difference between both protocols was tested for statistical significance using the Wilcoxon-Mann-Whitney test and the Two-Sample t-test.
Results: there was no statistically significant difference between both protocols regarding the technical quality of images, both in the AP (p = 0,46) and in the venous phase (p = 0,48). Additionally, no statistically significant difference was found regarding the presence of artefacts related to the contrast medium, both in the AP (p = 0,46) and in the venous phase (p = 0,46), as well as regarding the overall contrast quality of images both in the AP (p = 0,50) and in the venous phase (p = 0,48). Quantitative assessment showed no statistically significant difference regarding the difference in HU measurement between the hepatic lesion and the surrounding hepatic tissue, both in the AP (p = 0,36) and in the venous phase (p = 0,92).
Conclusion: in the multiphasic CT imaging of the liver, reducing the injection rate of the contrast medium Imeron from 5 ml/ sec to 3,7 ml/ sec while increasing the iodine strength of the agent from 300 to 400 mg/ml, respectively, and thus keeping the iodine injection flow rate constant, produces similar signal intensities and results in similar technical, image and overall contrast qualities..
Keywords: Contrast-medium, injection rate, iodine concentration, hepatic malignancy, multiphasic CT
Beside mosquitoes, ticks are well-known vectors of different human pathogens. In the Northern Hemisphere, Lyme borreliosis (Eurasia, LB) or Lyme disease (North America, LD) is the most commonly occurring vector-borne infectious disease caused by bacteria of the genus Borrelia which are transmitted by hard ticks of the genus Ixodes. The reported incidence of LB in Europe is about 22.6 cases per 100,000 inhabitants annually with a broad range depending on the geographical area analyzed. However, the epidemiological data are largely incomplete, because LB is not notifiable in all European countries. Furthermore, not only differ reporting procedures between countries, there is also variation in case definitions and diagnostic procedures. Lyme borreliosis is caused by several species of the Borrelia (B.) burgdorferi sensu lato (s.l.) complex which are maintained in complex networks including ixodid ticks and different reservoir hosts. Vector and host influence each other and are affected by multiple factors including climate that have a major impact on their habitats and ecology. To classify factors that influence the risk of transmission of B. burgdorferi s.l. to their different vertebrate hosts as well as to humans, we briefly summarize the current knowledge about the pathogens including their astonishing ability to overcome various host immune responses, regarding the main vector in Europe Ixodes ricinus, and the disease caused by borreliae. The research shows, that a higher standardization of case definition, diagnostic procedures, and standardized, long-term surveillance systems across Europe is necessary to improve clinical and epidemiological data.
The sympathetic nervous system (SNS) is a major regulatory mediator connecting the brain and the immune system that influences accordingly inflammatory processes within the entire body. In the periphery, the SNS exerts its effects mainly via its neurotransmitters norepinephrine (NE) and epinephrine (E), which are released by peripheral nerve endings in lymphatic organs and other tissues. Depending on their concentration, NE and E bind to specific α- and β-adrenergic receptor subtypes and can cause both pro- and anti-inflammatory cellular responses. The co-transmitter neuropeptide Y, adenosine triphosphate, or its metabolite adenosine are also mediators of the SNS. Local pro-inflammatory processes due to injury or pathogens lead to an activation of the SNS, which in turn induces several immunoregulatory mechanisms with either pro- or anti-inflammatory effects depending on neurotransmitter concentration or pathological context. In chronic inflammatory diseases, the activity of the SNS is persistently elevated and can trigger detrimental pathological processes. Recently, the sympathetic contribution to mild chronic inflammatory diseases like osteoarthritis (OA) has attracted growing interest. OA is a whole-joint disease and is characterized by mild chronic inflammation in the joint. In this narrative article, we summarize the underlying mechanisms behind the sympathetic influence on inflammation during OA pathogenesis. In addition, OA comorbidities also accompanied by mild chronic inflammation, such as hypertension, obesity, diabetes, and depression, will be reviewed. Finally, the potential of SNS-based therapeutic options for the treatment of OA will be discussed.
Autism Spectrum Disorder (ASD) is a neurodevelopmental condition with an onset in early development. ASD has varying degrees of severity and thus affects people differently throughout their lives. Early diagnosis of ASD is essential to provide children with individually-tailored support.8 Eye-tracking may contribute to an earlier diagnosis: Several studies showed differences in eye movements between people with autism spectrum disorder (ASD) and typically developing controls (TD). Different eye movements may contribute to different visual perception that perpetuates to problems in attention, communication and social interaction.
Eye movements are divided into: (1) Fixations (2) Saccades (fast and short eye movements) and (3) Smooth Pursuit Eye Movements (SPEM). SPEM follow the target in a continuous manner. The latter are the subject of the present thesis. SPEM consist of two phases: the open loop phase (= phase of initiation, first 50- 100ms) and the closed loop phase (= phase of maintenance, after about 100ms). SPEM are usually measured by a gain index. It is defined as the ratio of smooth pursuit velocity and visual target velocity and ideally equals to 1.2
In young children, corneal-reflection (CR) eye-tracking is usually applied to quantify eye movement. It allows precise measurements without the use of potentially intrusive devices.
Studies in ASD reported deficits in open loop and closed loop pursuit in children and adults with a mean age of 19.32 (TD) and 20.04 (ASD) years. However, SPEM in preschoolers with ASD remain understudied, although this developmental phase is crucial to the development of non-social and social attentional abilities.
In the present study 66 toddlers and preschoolers (18 to 72 months; ASD: n = 33, TD: n = 33) with matched cognitive abilities and sex were assessed. The main objective was to compare the gain index (Smooth Pursuit Gain = SPG). SPEM were compared between groups with gain index as a dependent measure. We hypothesized that participants with ASD show lower average gain compared to the control group.
We could show a significant group influence on the gain when considering interactions between target velocity and group (p = 0.041). The TD group showed a greater dependence on the increasing object speed than the ASD group with a trend of -0.30 ± 0.11 in the TD group and a trend of -0.13 ± 0.12 in the ASD group. Across groups, the gain decreased with increasing target velocity and dropped faster in vertical than in horizontal trials. Additionally, participants showed a lower SPG in vertical sequences than in horizontal sequences. This supports the general validity of the measure.
Toddlers and preschoolers represent a group that has been subject of little research to date. In addition, there has been only a limited number of studies analyzing SPEM in ASD. To check for a possible group difference without interactions a study with a larger sample size at fixed target velocity and target direction should follow.