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Background: In the Computer Tomography imaging, examinations for the diagnosis of lesions of the upper abdomen currently use water-soluble, iodinated, non-ionic contrast agents with low molecular weight. One possibility to reduce the time of the examination and X-ray exposure is to increase the injection rate. However, higher injections rates lead to increased hypersensitivity reactions and extravasation rates. Furthermore, cardiac pump function does not always allow for the transportation of such a large volume within one heartbeat. With a contrast agent of higher iodine concentration, the injection rate may be reduced without decreasing the iodine delivery rate while reducing the volume load of the heart.
Aim: to compare the performance and image quality of two injection protocols of contrast medium for multiphasic CT imaging of malignant hepatic lesions; one using Imeron 300 at an injection rate of 5 ml/ sec and the second using Imeron 400 at an injection rate of 3,7 ml/ sec, for multiphasic CT imaging of malignant hepatic lesions, in order to optimise the iodine concentration and injection rate of the contrast agent Imeron in the Multislice Spiral-CT of the upper abdomen.
Materials and methods: the current prospective, single centre, double-blinded, randomised and interindividual comparison study included 50 patients (29 males and 21 females) with a mean age of 63,3 years. Patients were randomised to one of the two injection protocols. Image evaluation included qualitative assessment (technical quality, presence of artefacts and overall contrast quality) and quantitative assessment (measuring the difference in HU between the lesion and the surrounding hepatic tissue). The difference between both protocols was tested for statistical significance using the Wilcoxon-Mann-Whitney test and the Two-Sample t-test.
Results: there was no statistically significant difference between both protocols regarding the technical quality of images, both in the AP (p = 0,46) and in the venous phase (p = 0,48). Additionally, no statistically significant difference was found regarding the presence of artefacts related to the contrast medium, both in the AP (p = 0,46) and in the venous phase (p = 0,46), as well as regarding the overall contrast quality of images both in the AP (p = 0,50) and in the venous phase (p = 0,48). Quantitative assessment showed no statistically significant difference regarding the difference in HU measurement between the hepatic lesion and the surrounding hepatic tissue, both in the AP (p = 0,36) and in the venous phase (p = 0,92).
Conclusion: in the multiphasic CT imaging of the liver, reducing the injection rate of the contrast medium Imeron from 5 ml/ sec to 3,7 ml/ sec while increasing the iodine strength of the agent from 300 to 400 mg/ml, respectively, and thus keeping the iodine injection flow rate constant, produces similar signal intensities and results in similar technical, image and overall contrast qualities..
Keywords: Contrast-medium, injection rate, iodine concentration, hepatic malignancy, multiphasic CT
A search for a massless dark photon 𝛾′ is conducted using 4.5 fb−1 of 𝑒+𝑒− collision data collected at center-of-mass energies between 4.600 and 4.699 GeV with the BESIII detector at BEPCII. No significant signal is observed, and the upper limit on the branching fraction ℬ(Λ+𝑐→𝑝𝛾′) is determined to be 8.0×10−5 at 90% confidence level.
A search for a massless dark photon γ′ is conducted using 4.5 fb−1 of e+e− collision data collected at center-of-mass energies between 4.600 and 4.699 GeV with the BESIII detector at BEPCII. No significant signal is observed, and the upper limit on the branching fraction B(Λ+c→pγ′) is determined to be 8.0×10−5 at 90% confidence level.
A search for a massless dark photon γ′ is conducted using 4.5 fb−1 of e+e− collision data collected at center-of-mass energies between 4.600 and 4.699 GeV with the BESIII detector at BEPCII. No significant signal is observed, and the upper limit on the branching fraction B(Λ+c→pγ′) is determined to be 8.0×10−5 at 90% confidence level.
Measurement of the absolute branching fraction of the singly Cabibbo suppressed decay Λc⁺ → pη′
(2022)
The singly Cabibbo suppressed decay Λ+c→pη′ is measured using 4.5 fb−1 of e+e− collision data collected at center-of-mass energies between 4.600 and 4.699 GeV with the BESIII detector at BEPCII. Evidence for Λ+c→pη′ with a statistical significance of 3.6σ is reported with a double-tag approach. The Λ+c→pη′ absolute branching fraction is determined to be (5.62+2.46−2.04±0.26)×10−4, where the first and second uncertainties are statistical and systematic, respectively. Our result is consistent with the branching fraction obtained by the Belle collaboration within the uncertainty of 1σ.
Measurement of the absolute branching fraction of the singly Cabibbo suppressed decay Λc⁺ → pη′
(2022)
The singly Cabibbo suppressed decay Λ+c→pη′ is measured using 4.5 fb−1 of e+e− collision data collected at center-of-mass energies between 4.600 and 4.699 GeV with the BESIII detector at BEPCII. Evidence for Λ+c→pη′ with a statistical significance of 3.6σ is reported with a double-tag approach. The Λ+c→pη′ absolute branching fraction is determined to be (5.62+2.46−2.04±0.26)×10−4, where the first and second uncertainties are statistical and systematic, respectively. Our result is consistent with the branching fraction obtained by the Belle collaboration within the uncertainty of 1σ.
Measurement of the absolute branching fraction of the singly Cabibbo suppressed decay Λc⁺ → pη′
(2022)
The singly Cabibbo suppressed decay Λ+𝑐→𝑝𝜂′ is measured using 4.5 fb−1 of 𝑒+𝑒− collision data collected at center-of-mass energies between 4.600 and 4.699 GeV with the BESIII detector at BEPCII. Evidence for Λ+𝑐→𝑝𝜂′ with a statistical significance of 3.6𝜎 is reported with a double-tag approach. The Λ+𝑐→𝑝𝜂′ absolute branching fraction is determined to be (5.62+2.46−2.04±0.26)×10−4, where the first and second uncertainties are statistical and systematic, respectively. Our result is consistent with the branching fraction obtained by the Belle collaboration within the uncertainty of 1𝜎.
Based on e+e− collision data collected at center-of-mass energies from 2.000 to 3.080 GeV by the BESIII detector at the BEPCII collider, a partial wave analysis is performed for the process e+e−→K0SK0Lπ0. The results allow the Born cross sections of the process e+e−→K0SK0Lπ0, as well as its subprocesses e+e−→K∗(892)0K¯0 and K∗2(1430)0K¯0 to be measured. The Born cross sections for e+e−→K0SK0Lπ0 are consistent with previous measurements by BaBar, but with substantially improved precision. The Born cross section lineshape of the process e+e−→K∗(892)0K¯0 is consistent with a vector meson state around 2.2 GeV with a significance of 3.2σ. A Breit-Wigner fit determines its mass as MY=(2164.7±9.1±3.1) MeV/c2 and its width as ΓY=(32.4±21.0±1.8) MeV.
Using a data sample of (1.0087±0.0044)×1010 J/ψ decay events collected with the BESIII detector at the center-of-mass energy of s√=3.097 GeV, we present a search for the hyperon semileptonic decay Ξ0→Σ−e+νe which violates the ΔS=ΔQ rule. No significant signal is observed, and the upper limit on the branching fraction B(Ξ0→Σ−e+νe) is determined to be 1.6×10−4 at the 90% confidence level. This result improves the previous upper limit result by about one order of magnitude.
Utilizing the data set corresponding to an integrated luminosity of 3.19 fb−1 collected by the BESIII detector at a center-of-mass energy of 4.178 GeV, we perform an amplitude analysis of the 𝐷+
𝑠→𝜋+𝜋−𝜋+ decay. The sample contains 13,797 candidates with a signal purity of ∼80%. The amplitude and phase of the contributing 𝜋𝜋 𝒮 wave are measured based on a quasi-model-independent approach, along with the amplitudes and phases of the 𝒫 and 𝒟 waves parametrized by Breit-Wigner models. The fit fractions of different intermediate decay channels are also reported.