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We show examples of the impact of the Maxwellian averaged capture cross sections determined at n_TOF over the past 20 years on AGB stellar nucleosynthesis models. In particular, we developed an automated procedure to derive MACSs from evaluated data libraries, which are subsequently used as input to stellar models computed by means of the FuNS code. In this contribution, we present a number of s-process abundances obtained using different data libraries as input to stellar models, with a focus on the role of n_TOF data.
Objective: Deep brain stimulation (DBS) of the ventral intermediate nucleus (VIM) is a mainstay treatment for severe and drug-refractory essential tremor (ET). Although stimulation-induced dysarthria has been extensively described, possible impairment of swallowing has not been systematically investigated yet. Methods: Twelve patients with ET and bilateral VIM-DBS with self-reported dysphagia after VIM-DBS were included. Swallowing function was assessed clinically and using by flexible endoscopic evaluation of swallowing in the stim-ON and in the stim-OFF condition. Presence, severity, and improvement of dysphagia were recorded. Results: During stim-ON, the presence of dysphagia could be objectified in all patients, 42% showing mild, 42% moderate, and 16 % severe dysphagia. During stim-OFF, all patients experienced a statistically significant improvement of swallowing function. Interpretation: VIM-DBS may have an impact on swallowing physiology in ET-patients. Further studies to elucidate the prevalence and underlying pathophysiological mechanisms are warranted.
Ischemic lesion location based on the ASPECT score for risk assessment of neurogenic dysphagia
(2020)
Dysphagia is common in patients with middle cerebral artery (MCA) infarctions and associated with malnutrition, pneumonia, and mortality. Besides bedside screening tools, brain imaging findings may help to timely identify patients with swallowing disorders. We investigated whether the Alberta stroke program early CT score (ASPECTS) allows for the correlation of distinct ischemic lesion patterns with dysphagia. We prospectively examined 113 consecutive patients with acute MCA infarctions. Fiberoptic endoscopic evaluation of swallowing (FEES) was performed within 24 h after admission for validation of dysphagia. Brain imaging (CT or MRI) was rated for ischemic changes according to the ASPECT score. 62 patients (54.9%) had FEES-proven dysphagia. In left hemispheric strokes, the strongest associations between the ASPECTS sectors and dysphagia were found for the lentiform nucleus (odds ratio 0.113 [CI 0.028–0.433; p = 0.001), the insula (0.275 [0.102–0.742]; p = 0.011), and the frontal operculum (0.280 [CI 0.094–0.834]; p = 0.022). A combination of two or even all three of these sectors together increased relative dysphagia frequency up to 100%. For right hemispheric strokes, only non-significant associations were found which were strongest for the insula region. The distribution of early ischemic changes in the MCA territory according to ASPECTS may be used as risk indicator of neurogenic dysphagia in MCA infarction, particularly when the left hemisphere is affected. However, due to the exploratory nature of this research, external validation studies of these findings are warranted in future.
Background: While swallowing disorders are frequent sequela following posterior fossa tumor (PFT) surgery in children, data on dysphagia frequency, severity, and outcome in adults are lacking. The aim of this study was to investigate dysphagia before and after surgical removal of PFT. Additionally, we tried to identify clinical predictors for postsurgical swallowing disorders. Furthermore, this study explored the three-month outcome of dysphagic patients.
Methods: In a cohort of patients undergoing PFT surgery, dysphagia was prospectively assessed pre- and postoperatively using fiberoptic endoscopic evaluation of swallowing. Patients with severe dysphagia at discharge were re-evaluated after three months. Additionally, clinical and imaging data were collected to identify predictors for post-surgical dysphagia. Results: We included 26 patients of whom 15 had pre-operative swallowing disorders. After surgery, worsening of pre-existing dysphagia could be noticed in 7 patients whereas improvement was observed in 2 and full recovery in 3 subjects. New-onset dysphagia after surgery occurred in a minority of 3 cases. Postoperatively, 47% of dysphagic patients required nasogastric tube feeding. Re-evaluation after three months of follow-up revealed that all dysphagic patients had returned to full oral intake.
Conclusion: Dysphagia is a frequent finding in patients with PFT already before surgery. Surgical intervention can infer a deterioration of impaired swallowing function placing affected patients at temporary risk for aspiration. In contrast, surgery can also accomplish beneficial results resulting in both improvement and full recovery. Overall, our findings show the need of early dysphagia assessment to define the safest feeding route for the patient.
Tragosoma soror (Coleoptera: Cerambycidae: Prioninae), a new Nearctic species, is described and compared to its North American congeners. Tragosoma harrisii LeConte, revised status, and Tragosoma spiculum Casey, revised status are both resurrected from synonymy and considered valid species distinct from T. depsarium (Linnaeus). The Mexican T. nigripenne Bates is confi rmed as a valid species. Tragosoma chiricahuae Linsley, new synonym, is placed in synonymy under T. spiculum Casey, and T. sodale Casey, new synonym, T. parvicolle Casey, new synonym, and T. repens Casey new synonym are placed in synonymy under T. harrisii. Tragosoma repens is a junior objective synonym of T. parvicolle. A lectotype is designated for T. sodale. An updated synonymical and distributional checklist of Tragosoma of the world is provided.
Since the mid-1970's, the question of whether or not a verb agreement system1 (VAS) should be reconstructed for Proto-Tibeto-Bunnan (PTB) has been a controversial topic, but because of the large amount of work published arguing in favor of reconstructing a VAS for PTB, especially by James J. Bauman (1974, 1975a, 1975b, 1979) and Scott DeLancey (1980, 1983, 1988, 1989, to appear), many people have begun to accept the existence of a VAS in PTB as received knowledge. In a recent paper on verb agreement systems in Tibeto-Burman, Scott DeLancey states that 'There can no longer be any serious doubt that a system of verb agreement must be attributed to Proto-Tibeto-Bunnan (PTB)' (DeLancey 1988: 1). Though the number of papers supporting this position is quite large, I would like to raise several serious doubts about the theoretical and methodological basis for reconstructing a VAS for PTB' and at the same time argue for the use of functionally and typologically based theories of grammar, as exemplified by the head-marking/dependent-marking distinction developed in Nichols 1986, in diachronic syntax and syntactic reconstruction.
In attempting to reconstruct the morphosyntax of Proto-Sino-Tibetan, one of the most basic questions to be answered is what was the unmarked word order of the proto-language? Chinese, Bai, and Karen are verb-medial languages, while all of the Tibeto-Burman languages except for Bai and Karen have verb-final word order. lf these languages are all related, as we can assume from lexical correspondences, then either Chinese, Bai and Karen changed from verb-final to verb-medial word order, or the other Tibeto-Burman languages changed trom verb-medial to verb-final order. How we answer the question of which languages changed their word would then give us the answer to the question of word order in Proto-Sino-Tibetan.
This paper is an inductive look at the constituents found in a randomly selected Tagalog text, Bob Ong’s Alamat ng Gubat (Makati City, MM: Visual Print Enterprises, 2004). The analysis is based on the full text, but we will only be able to go through the first few lines of the text here, which we will do one by one, and discuss the structures found in each line of the text in bullet format after the relevant line. At the end of the paper we will bring up some important questions about the structures found in Tagalog based on this text.