WOME : theory-based working memory training — a placebo-controlled, double-blind evaluation in older adults

  • Background: Scientifically evaluated cognitive intervention programs are essential to meet the demands of our increasingly aging society. Currently, one of the “hottest” topics in the field is the improvement of working memory function and its potential impact on overall cognition. The present study evaluated the efficacy of WOME (WOrking MEmory), a theory-based working memory training program, in a double-blind, placebo-controlled, and randomized controlled trial (www.drks.de, DRKS00013162). Methods: N = 60 healthy older adults were allocated to (1) the WOME intervention, (2) an active low-level intervention, or (3) a passive control group. Overall, the intervention groups practiced twelve sessions of 45 min within 4 weeks of their respective training. Transfer effects were measured via an extensive battery of neuropsychological tests and questionnaires both pre-/post-training and at a 3-month follow-up. Results: WOME led to a significant improvement in working memory function, demonstrated on a non-trained near transfer task and on two different composite scores with moderate to large effect sizes. In addition, we found some indication of relevant impact on everyday life. The effects were short-term rather than stable, being substantially diminished at follow-up with only little evidence suggesting long-term maintenance. No transfer effects on other cognitive functions were observed. Conclusion: WOME is an appropriate and efficient intervention specifically targeting the working memory system in healthy older adults. Trial Registration: German Clinical Trials Register (DRKS), Identifier: DRKS00013162.

Download full text files

Export metadata

Author:Juliane Weicker, Nicole Hudl, Stefan Frisch, Jöran Lepsien, Karsten Mueller, Arno Villringer, Angelika Thöne-Otto
Pubmed Id:https://pubmed.ncbi.nlm.nih.gov/30154713
Parent Title (English):Frontiers in aging neuroscience
Publisher:Frontiers Research Foundation
Place of publication:Lausanne
Contributor(s):Lutz Jäncke
Document Type:Article
Year of Completion:2018
Date of first Publication:2018/08/14
Publishing Institution:Universitätsbibliothek Johann Christian Senckenberg
Release Date:2018/10/25
Tag:aging; cognitive decline; cognitive training; mild cognitive impairment; neuropsychology; plasticity; rehabilitation; working memory training
Issue:Art. 247
Page Number:14
First Page:1
Last Page:14
Copyright © 2018 Weicker, Hudl, Frisch, Lepsien, Mueller, Villringer and Thöne-Otto. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
Institutes:Psychologie und Sportwissenschaften / Psychologie
Dewey Decimal Classification:1 Philosophie und Psychologie / 15 Psychologie / 150 Psychologie
Licence (German):License LogoCreative Commons - Namensnennung 4.0