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Neuartige, metabolisch aktive Organellen in eukaryotischen Zellen

  • Microbial production of chemicals is a sustainable alternative to conventional industrial processes. However, the implementation of exogenous metabolic pathways is hampered by slow diffusion rates, competing pathways, or secretion of intermediates. Pre-existing organelles have been harnessed to overcome these problems, but these approaches suffer from interference with endogenous pathways. We have developed a new concept for the compartmentalization of enzymatic pathways in ER-derived vesicles.

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Author:Joanna TrippORCiDGND, Igor-Mislav OrebORCiDGND, Eckhard BolesORCiD
URN:urn:nbn:de:hebis:30:3-694865
DOI:https://doi.org/10.1007/s12268-022-1777-7
ISSN:1868-6249
Parent Title (German):Biospektrum
Publisher:Spektrum
Place of publication:Heidelberg
Document Type:Article
Language:German
Date of Publication (online):2022/06/09
Date of first Publication:2022/06/09
Publishing Institution:Universitätsbibliothek Johann Christian Senckenberg
Release Date:2023/05/11
Volume:28
Issue:4
Page Number:3
First Page:397
Last Page:399
Note:
Open Access funding enabled and organized by Projekt DEAL.
Note:
Die Autoren danken dem Bundesministerium für Bildung und Forschung (FKZ: 031A542 und 031B0218) für die finanzielle Unterstützung ihrer Arbeiten zur künstlichen Kompartimentierung.
Institutes:Biowissenschaften
Dewey Decimal Classification:5 Naturwissenschaften und Mathematik / 57 Biowissenschaften; Biologie / 570 Biowissenschaften; Biologie
Sammlungen:Universitätspublikationen
Licence (German):License LogoCreative Commons - CC BY - Namensnennung 4.0 International