Hector A. Cabrera-Fuentes, Julian Aragones, Jürgen Bernhagen, Andreas Boening, William A. Boisvert, Hans E. Bøtker, Heerajnarain Bulluck, Stuart Cook, Fabio Di Lisa, Felix B. Engel, Bernd Engelmann, Fulvia Ferrazzi, Peter Ferdinandy, Alan Fong, Ingrid Fleming, Erich Gnaiger, Sauri Hernández-Reséndiz, Siavash Beikoghli Kalkhoran, Moo Hyun Kim, Sandrine Lecour, Elisa A. Liehn, Michael S. Marber, Manuel Mayr, Tetsuji Miura, Sang-Bing Ong, Karlheinz Peter, Daniel Sedding, Manvendra K. Singh, M. Saadeh Suleiman, Hans J. Schnittler, Rainer Schulz, Winston Shim, Daniel Tello, Carl-Wilhelm Vogel, Malcolm Walker, Qilong Oscar Yang Li, Derek M. Yellon, Derek J. Hausenloy, Klaus T. Preissner
- In this meeting report, particularly addressing the topic of protection of the cardiovascular system from ischemia/reperfusion injury, highlights are presented that relate to conditioning strategies of the heart with respect to molecular mechanisms and outcome in patients’ cohorts, the influence of co-morbidities and medications, as well as the contribution of innate immune reactions in cardioprotection. Moreover, developmental or systems biology approaches bear great potential in systematically uncovering unexpected components involved in ischemia–reperfusion injury or heart regeneration. Based on the characterization of particular platelet integrins, mitochondrial redox-linked proteins, or lipid-diol compounds in cardiovascular diseases, their targeting by newly developed theranostics and technologies opens new avenues for diagnosis and therapy of myocardial infarction to improve the patients’ outcome.
Metadaten| Verfasserangaben: | Hector A. Cabrera-Fuentes, Julian Aragones, Jürgen BernhagenGND, Andreas Boening, William A. Boisvert, Hans E. Bøtker, Heerajnarain Bulluck, Stuart Cook, Fabio Di Lisa, Felix B. EngelORCiDGND, Bernd Engelmann, Fulvia Ferrazzi, Peter Ferdinandy, Alan Fong, Ingrid FlemingORCiDGND, Erich Gnaiger, Sauri Hernández-Reséndiz, Siavash Beikoghli Kalkhoran, Moo Hyun Kim, Sandrine Lecour, Elisa A. Liehn, Michael S. Marber, Manuel Mayr, Tetsuji Miura, Sang-Bing Ong, Karlheinz Peter, Daniel Sedding, Manvendra K. Singh, M. Saadeh Suleiman, Hans J. Schnittler, Rainer Schulz, Winston Shim, Daniel Tello, Carl-Wilhelm Vogel, Malcolm Walker, Qilong Oscar Yang Li, Derek M. Yellon, Derek J. Hausenloy, Klaus T. PreissnerGND |
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| URN: | urn:nbn:de:hebis:30:3-427376 |
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| DOI: | https://doi.org/10.1007/s00395-016-0586-x |
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| ISSN: | 1435-1803 |
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| Titel des übergeordneten Werkes (Englisch): | Basic research in cardiology |
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| Verlag: | Springer |
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| Verlagsort: | Heidelberg |
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| Dokumentart: | Wissenschaftlicher Artikel |
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| Sprache: | Englisch |
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| Jahr der Fertigstellung: | 2016 |
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| Datum der Erstveröffentlichung: | 14.10.2016 |
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| Veröffentlichende Institution: | Universitätsbibliothek Johann Christian Senckenberg |
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| Datum der Freischaltung: | 31.01.2017 |
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| Freies Schlagwort / Tag: | Cardiomyocyte signaling pathways; Cardioprotection; Cardiovascular disease; Comorbidities; Drug targeting; Endothelial permeability; Extracellular RNA (eRNA); Heart regeneration; Induced pluripotent stem cells; Ischemia–reperfusion injury; Lipid metabolism; MicroRNAs (miRNAs); Mitochondria; Remote ischemic conditioning |
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| Jahrgang: | 111 |
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| Ausgabe / Heft: | 69 |
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| Seitenzahl: | 13 |
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| Erste Seite: | 1 |
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| Letzte Seite: | 13 |
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| Bemerkung: | This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
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| HeBIS-PPN: | 451941292 |
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| Institute: | Medizin / Medizin |
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| DDC-Klassifikation: | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
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| Sammlungen: | Universitätspublikationen |
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| Lizenz (Deutsch): |  Creative Commons - Namensnennung 4.0 |
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Creative Commons - Namensnennung 4.0