Long term seizure freedom on perampanel in highly drug-resistant epilepsy caused by bilateral periventricular nodular heterotopia: a case report
- Highlights • NMDA-receptor subunit expression of NR2A and NR2B is downregulated in heterotopias. • Glutamatergic transmission in the hyperexcitability of nodular heterotopias is implicated. • Mechanisms in PVNH to establish etiology specific therapies are still to be defined.
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| Author: | Makoto KiyoseGND, Marlies WagnerORCiDGND, Annika Männer, Sarah ReitzORCiDGND, Karl Martin KleinORCiD, Adam StrzelczykORCiDGND, Sebastian BauerORCiDGND, Felix RosenowORCiDGND |
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| URN: | urn:nbn:de:hebis:30:3-775004 |
| DOI: | https://doi.org/10.1016/j.ebcr.2019.01.009 |
| ISSN: | 2213-3232 |
| Parent Title (English): | Epilepsy & behavior case reports |
| Publisher: | Elsevier |
| Place of publication: | Amsterdam |
| Document Type: | Article |
| Language: | English |
| Date of Publication (online): | 2019/02/25 |
| Date of first Publication: | 2019/02/13 |
| Publishing Institution: | Universitätsbibliothek Johann Christian Senckenberg |
| Release Date: | 2024/06/03 |
| Volume: | 11 |
| Page Number: | 4 |
| First Page: | 99 |
| Last Page: | 102 |
| HeBIS-PPN: | 519157842 |
| Institutes: | Medizin |
| Dewey Decimal Classification: | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
| Sammlungen: | Universitätspublikationen |
| Licence (German): |  Creative Commons - CC BY-NC-ND - Namensnennung - Nicht kommerziell - Keine Bearbeitungen 4.0 International |
