Virtual non-calcium dual-energy CT: clinical applications

  • Dual-energy CT (DECT) has emerged into clinical routine as an imaging technique with unique postprocessing utilities that improve the evaluation of different body areas. The virtual non-calcium (VNCa) reconstruction algorithm has shown beneficial effects on the depiction of bone marrow pathologies such as bone marrow edema. Its main advantage is the ability to substantially increase the image contrast of structures that are usually covered with calcium mineral, such as calcified vessels or bone marrow, and to depict a large number of traumatic, inflammatory, infiltrative, and degenerative disorders affecting either the spine or the appendicular skeleton. Therefore, VNCa imaging represents another step forward for DECT to image conditions and disorders that usually require the use of more expensive and time-consuming techniques such as magnetic resonance imaging, positron emission tomography/CT, or bone scintigraphy. The aim of this review article is to explain the technical background of VNCa imaging, showcase its applicability in the different body regions, and provide an updated outlook on the clinical impact of this technique, which goes beyond the sole improvement in image quality.

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Author:Tommaso D’AngeloORCiD, Moritz Hans Ernst AlbrechtORCiDGND, Danilo Caudo, Silvio MazziottiORCiD, Thomas J. VoglORCiDGND, Julian WichmannORCiDGND, Simon MartinORCiDGND, Ibrahim YelORCiDGND, Giorgio Ascenti, Vitali KochORCiDGND, Giuseppe Cicero, Alfredo Blandino, Christian BoozORCiDGND
Parent Title (English):European radiology experimental
Publisher:Springer International Publishing
Place of publication:[Cham]
Document Type:Article
Date of Publication (online):2021/09/03
Date of first Publication:2021/09/03
Publishing Institution:Universitätsbibliothek Johann Christian Senckenberg
Release Date:2022/06/01
Tag:Algorithms; Bone marrow; Calcium; Edema; Tomography (x-ray computed)
Issue:art. 38
Page Number:13
First Page:1
Last Page:13
Open Access funding enabled and organized by Projekt DEAL.
Dewey Decimal Classification:6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit
Licence (German):License LogoCreative Commons - Namensnennung 4.0