Gesche M. Voigt, Dominik Thiele, Martin Wetzke, Jürgen Weidemann, Patricia‐Maria Parpatt, Tobias Welte, Jürgen Seidenberg, Christian Vogelberg, Holger Köster, Gernot Gerhard Ulrich Rohde, Christoph Härtel, Gesine Hansen, Matthias Kopp
- Although chest radiograph (CXR) is commonly used in diagnosing pediatric community acquired pneumonia (pCAP), limited data on interobserver agreement among radiologists exist. PedCAPNETZ is a prospective, observational, and multicenter study on pCAP. N = 233 CXR from patients with clinical diagnosis of pCAP were retrieved and n = 12 CXR without pathological findings were added. All CXR were interpreted by a radiologist at the site of recruitment and by two external, blinded pediatric radiologists. To evaluate interobserver agreement, the reporting of presence or absence of pCAP in CXR was analyzed, and prevalence and bias-adjusted kappa (PABAK) statistical testing was applied. Overall, n = 190 (82%) of CXR were confirmed as pCAP by two external pediatric radiologists. Compared with patients with pCAP negative CXR, patients with CXR-confirmed pCAP displayed higher C-reactive protein levels and a longer duration of symptoms before enrollment (p < .007). Further parameters, that is, age, respiratory rate, and oxygen saturation showed no significant difference. The interobserver agreement between the onsite radiologists and each of the two independent pediatric radiologists for the presence of pCAP was poor to fair (69%; PABAK = 0.39% and 76%; PABAK = 0.53, respectively). The concordance between the external radiologists was fair (81%; PABAK = 0.62). With regard to typical CXR findings for pCAP, chance corrected interrater agreement was highest for pleural effusions, infiltrates, and consolidations and lowest for interstitial patterns and peribronchial thickening. Our data show a poor interobserver agreement in the CXR-based diagnosis of pCAP and emphasized the need for harmonized interpretation standards.
MetadatenAuthor: | Gesche M. Voigt, Dominik ThieleORCiD, Martin WetzkeGND, Jürgen WeidemannORCiD, Patricia‐Maria Parpatt, Tobias WelteORCiDGND, Jürgen SeidenbergGND, Christian VogelbergGND, Holger KösterGND, Gernot Gerhard Ulrich RohdeORCiDGND, Christoph HärtelGND, Gesine HansenORCiDGND, Matthias KoppORCiDGND |
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URN: | urn:nbn:de:hebis:30:3-639790 |
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DOI: | https://doi.org/10.1002/ppul.25528 |
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ISSN: | 1099-0496 |
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Parent Title (English): | Pediatric pulmonology |
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Publisher: | Wiley-Liss |
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Place of publication: | New York, NY |
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Document Type: | Article |
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Language: | English |
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Date of Publication (online): | 2021/06/02 |
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Date of first Publication: | 2021/06/02 |
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Publishing Institution: | Universitätsbibliothek Johann Christian Senckenberg |
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Release Date: | 2023/02/10 |
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Tag: | antibiotic therapy; imaging; infections: pneumonia, TB, viral |
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Volume: | 56 |
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Issue: | 8 |
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Page Number: | 10 |
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First Page: | 2676 |
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Last Page: | 2685 |
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Note: | This project was supported by the German Center for Lung Research (DZL) by funding for biosampling and infrastructure |
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Note: | The clinical trial was funded by the CAP-Net foundation and supported by the German Center for Lung Research (DZL). |
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HeBIS-PPN: | 507182995 |
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Institutes: | Medizin / Medizin |
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Dewey Decimal Classification: | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
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Sammlungen: | Universitätspublikationen |
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Licence (German): | Creative Commons - CC BY-ND - Namensnennung - Keine Bearbeitungen 4.0 International |
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