- Highlights
• Short- and long-delay memory consolidation is less robust in children than in young adults.
• Short-delay brain profile comprised of hippocampal, cerebellar, and neocortical brain regions.
• Long-delay brain profile comprised of neocortical and selected hippocampal brain regions.
• Brain profiles differ between children and young adults.
Abstract
From early to middle childhood, brain regions that underlie memory consolidation undergo profound maturational changes. However, there is little empirical investigation that directly relates age-related differences in brain structural measures to memory consolidation processes. The present study examined memory consolidation of intentionally studied object-location associations after one night of sleep (short delay) and after two weeks (long delay) in normally developing 5-to-7-year-old children (n = 50) and young adults (n = 39). Behavioural differences in memory retention rate were related to structural brain measures. Our results showed that children, in comparison to young adults, retained correctly learnt object-location associations less robustly over short and long delay. Moreover, using partial least squares correlation method, a unique multivariate profile comprised of specific neocortical (prefrontal, parietal, and occipital), cerebellar, and hippocampal head and subfield structures in the body was found to be associated with variation in short-delay memory retention. A different multivariate profile comprised of a reduced set of brain structures, mainly consisting of neocortical (prefrontal, parietal, and occipital), hippocampal head, and selective hippocampal subfield structures (CA1–2 and subiculum) was associated with variation in long-delay memory retention. Taken together, the results suggest that multivariate structural pattern of unique sets of brain regions are related to variations in short- and long-delay memory consolidation across children and young adults.
MetadatenAuthor: | Iryna SchommartzORCiDGND, Philip F. LembckeORCiD, Francesco PupilloORCiD, Henriette Schuetz, Nina Wald de ChamorroORCiDGND, Martin BauerORCiD, Angela M. KaindlORCiDGND, Claudia BußORCiDGND, Yee Lee ShingORCiDGND |
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URN: | urn:nbn:de:hebis:30:3-787920 |
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DOI: | https://doi.org/10.1016/j.dcn.2022.101192 |
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ISSN: | 1878-9293 |
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Parent Title (English): | Developmental cognitive neuroscience |
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Publisher: | Elsevier |
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Place of publication: | Amsterdam |
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Document Type: | Article |
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Language: | English |
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Date of Publication (online): | 2022/12/23 |
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Date of first Publication: | 2022/12/23 |
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Publishing Institution: | Universitätsbibliothek Johann Christian Senckenberg |
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Release Date: | 2024/06/03 |
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Tag: | Episodic memory; Hippocampal subfields; Memory consolidation; Neocortex; Object-scene associations; Partial least square correlation; Prefrontal cortex |
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Volume: | 59.2023 |
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Issue: | 101192 |
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Article Number: | 101192 |
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Page Number: | 14 |
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HeBIS-PPN: | 519156110 |
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Institutes: | Psychologie und Sportwissenschaften / Psychologie |
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Dewey Decimal Classification: | 1 Philosophie und Psychologie / 15 Psychologie / 150 Psychologie |
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| 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
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Sammlungen: | Universitätspublikationen |
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Licence (German): | Creative Commons - CC BY-NC-ND - Namensnennung - Nicht kommerziell - Keine Bearbeitungen 4.0 International |
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