Medizin
Refine
Year of publication
Has Fulltext
- yes (541) (remove)
Is part of the Bibliography
- no (541)
Keywords
- inflammation (29)
- macrophage (13)
- glioblastoma (10)
- cancer (9)
- SARS-CoV-2 (8)
- hypoxia (8)
- prostate cancer (8)
- apoptosis (7)
- data science (7)
- macrophages (7)
- pain (7)
- epilepsy (6)
- macrophage polarization (6)
- miRNA (6)
- microRNA (6)
- COVID-19 (5)
- Cirrhosis (5)
- autophagy (5)
- breast cancer (5)
- curcumin (5)
- differentiation (5)
- environmental tobacco smoke (5)
- lipocalin-2 (5)
- multiple sclerosis (5)
- neurodegeneration (5)
- particulate matter (5)
- prevalence (5)
- proliferation (5)
- stroke (5)
- Aspergillus (4)
- B cells (4)
- Gene expression (4)
- Hemorrhage (4)
- Labor and delivery (4)
- Liver diseases (4)
- MSD (4)
- NKG2D (4)
- Pregnancy (4)
- ataxia telangiectasia (4)
- biomarker (4)
- bipolar disorder (4)
- bladder cancer (4)
- child (4)
- children (4)
- endothelial cells (4)
- epidemiology (4)
- immunotherapy (4)
- infection (4)
- integrins (4)
- iron (4)
- mTOR (4)
- machine learning (4)
- mesenchymal stromal/stem cells (4)
- migration (4)
- obesity (4)
- outcome (4)
- polytrauma (4)
- psoriasis (4)
- radical prostatectomy (4)
- sphingosine-1-phosphate (4)
- sulforaphane (4)
- thymus (4)
- tumor microenvironment (4)
- Acute myeloid leukemia (3)
- Cancer treatment (3)
- DNA methylation (3)
- Death rates (3)
- EEG microstates (3)
- Evaluation (3)
- Gender (3)
- General practice (3)
- Hepatocellular carcinoma (3)
- Inflammation (3)
- Kinematic analysis (3)
- Knees (3)
- Legs (3)
- Macrophages (3)
- Magnetic resonance imaging (3)
- Medical risk factors (3)
- Morbidity (3)
- Multimorbidity (3)
- Multivariate analysis (3)
- Musculoskeletal system (3)
- NK cells (3)
- NoxO1 (3)
- PCR (3)
- Pain (3)
- Polypharmacy (3)
- acetaminophen (3)
- aging (3)
- angiogenesis (3)
- bevacizumab (3)
- caspase-2 (3)
- ceramides (3)
- cirrhosis (3)
- colorectal cancer (3)
- complement (3)
- cytokines (3)
- dental profession (3)
- dentate gyrus (3)
- dentist (3)
- drug resistance (3)
- electrolytic cleaning (3)
- entropy (3)
- exercise (3)
- flow cytometry (3)
- glioma (3)
- growth (3)
- immunity (3)
- information theory (3)
- innate immunity (3)
- invasion (3)
- invasive fungal disease (3)
- meningioma (3)
- metabolism (3)
- metastasis (3)
- mitochondria (3)
- monocytes (3)
- mortality (3)
- mutual information (3)
- natural killer cell (3)
- neuroblastoma (3)
- neuropathic pain (3)
- osteoarthritis (3)
- p21 (3)
- periimplantitis (3)
- preeclampsia (3)
- proteomics (3)
- public health (3)
- quality of life (3)
- questionnaire (3)
- reactive oxygen species (3)
- regeneration (3)
- systematic biopsy (3)
- trauma (3)
- tumor progression (3)
- vitamin D (3)
- working memory (3)
- ADHD (2)
- ATM (2)
- ATP-citrate lyase (2)
- Angiogenesis (2)
- Angiography (2)
- Asphyxia (2)
- Ataxia telangiectasia (2)
- BCL6 (2)
- BPH (2)
- Biomarker (2)
- Birth weight (2)
- Blood (2)
- Borrelia (2)
- Brain metastasis (2)
- Breast cancer (2)
- Breast tumors (2)
- C-reactive protein (2)
- CC16 (2)
- CD44 (2)
- CDKN1A (2)
- CIK cells (2)
- CLP (2)
- COMP (2)
- CUELA (2)
- Cancer chemotherapy (2)
- Candida (2)
- Cell binding (2)
- Cell differentiation (2)
- Cesarean section (2)
- Chemotherapy (2)
- Citation analysis (2)
- Cohort studies (2)
- Crohn's disease (2)
- Crohn’s disease (2)
- Cuela (2)
- Cytokines (2)
- Density equalizing mapping (2)
- Dentist (2)
- Depression (2)
- Diagnostic medicine (2)
- Ears (2)
- G2A (2)
- GPCR (2)
- HDAC (2)
- HIV (2)
- Holmes tremor (2)
- IBD (2)
- Inflammatory bowel disease (2)
- Intensive care units (2)
- Ischemia (2)
- Jaw (2)
- LSCC (2)
- Lesions (2)
- MICA (2)
- Malaria (2)
- Markovianity (2)
- Medical education (2)
- Mental health and psychiatry (2)
- Messenger RNA (2)
- Methicillin-resistant Staphylococcus aureus (2)
- Mouse models (2)
- Musculoskeletal disorder (2)
- Myalgia (2)
- NADH dehydrogenase (2)
- NADPH oxidase (2)
- NAFLD (2)
- NASH (2)
- NK cells (2)
- Neonates (2)
- Neutropenia (2)
- Normal distribution (2)
- Nox1 (2)
- OXA-48 (2)
- Obstetrics and gynecology (2)
- Patients (2)
- Physicians (2)
- Portal hypertension (2)
- Portal veins (2)
- Postural control (2)
- Preterm birth (2)
- Prognosis (2)
- Protease inhibitor therapy (2)
- Psychology (2)
- Quality of life (2)
- Questionnaire (2)
- RNF4 (2)
- ROS (2)
- Regression analysis (2)
- Reliability (2)
- Research architecture (2)
- Surgery (2)
- T cell (2)
- T cells (2)
- Torque (2)
- Transcription factors (2)
- Treg cell (2)
- Ulcerative colitis (2)
- Vitamin D (2)
- acetyl-CoA (2)
- additives (2)
- adhesion (2)
- adipose-derived mesenchymal stem cells (2)
- air flow (2)
- alcohol (2)
- anaemia (2)
- anal cancer (2)
- anticonvulsants (2)
- antiviral therapy (2)
- ascites (2)
- atherosclerosis (2)
- augmentation (2)
- bibliometrics (2)
- bibliometry (2)
- bio imaging (2)
- bioluminescence (2)
- blood (2)
- borrelia (2)
- calretinin (2)
- cancer stem cells (2)
- carbapenemases (2)
- cardiac surgery (2)
- cell cycle (2)
- cervical cancer (2)
- chemotherapy (2)
- chemotherapy resistance (2)
- cholesterol (2)
- classical Hodgkin lymphoma (2)
- coagulopathy (2)
- cochlear implant (2)
- colon cancer (2)
- colon carcinoma cells (2)
- colorectal carcinoma (2)
- complications (2)
- concordance (2)
- corona virus (2)
- coronavirus (2)
- cyclosporin A (2)
- dance (2)
- dendritic cells (2)
- dental assistants (2)
- dental education (2)
- dental implant (2)
- dentists (2)
- depression (2)
- disintegration (2)
- elderly (2)
- encoding (2)
- exosomes (2)
- extracellular vesicles (2)
- fMRI (2)
- female subjects (2)
- fibroblasts (2)
- forensic entomology (2)
- functional genomics (2)
- fusion (2)
- fusion biopsy (2)
- gender (2)
- gene expression (2)
- gene regulation (2)
- histology (2)
- histone acetylation (2)
- human genomics (2)
- imaging (2)
- immune evasion (2)
- immunohistochemistry (2)
- inflammatory bowel disease (2)
- integrin (2)
- interleukin-4 (2)
- iron deficiency (2)
- iron metabolism (2)
- irradiation (2)
- knowledge discovery (2)
- layer-specificity (2)
- lipoxygenase (2)
- liver damage (2)
- liver fibrosis (2)
- liver transplantation (2)
- lung cancer (2)
- lyme disease (2)
- maintenance (2)
- methylprednisolone (2)
- miR-181 (2)
- mouse (2)
- mucormycetes (2)
- multinucleated giant cells (2)
- musculoskeletal (2)
- mycophenolic acid (2)
- natural killer cells (2)
- neurogenesis (2)
- next generation sequencing (NGS) (2)
- occupational health (2)
- olfaction (2)
- oxidative phosphorylation (2)
- oxidative stress (2)
- palatal tremor (2)
- patient (2)
- patients (2)
- perforant path transection (2)
- phagocytes (2)
- physical activity (2)
- plasmid (2)
- primary care (2)
- primary cilium (2)
- primary immunodeficiency (2)
- proteome (2)
- qRT-PCR (2)
- quantitative MRI (2)
- re-osseointegration (2)
- regulatory T cell (2)
- renal cell cancer (2)
- renal cell carcinoma (2)
- renal tubular epithelial cells (2)
- respiratory chain (2)
- schizophrenia (2)
- second-hand smoke (2)
- secretion (2)
- seizure (2)
- selection (2)
- sex (2)
- signal transduction (2)
- sound-induced flash illusion (2)
- sphingosine 1-phosphate (2)
- sphingosine 1-phosphate receptor (2)
- spirochetes (2)
- standard value (2)
- starvation (2)
- stationarity (2)
- surgery (2)
- survivin (2)
- tissue engineering (2)
- total hip replacement (2)
- toxicity (2)
- tracking (2)
- transfusion (2)
- trophoblast (2)
- trophoblasts (2)
- tumor growth (2)
- tumor-associated macrophages (2)
- uteroglobin (2)
- (novel) brominated flame retardants ((N)BFR) (1)
- 16 segment AHA model (1)
- 16p11.2 (1)
- 17-AAG (1)
- 2-deoxyglucose (2-DG) (1)
- 3D gait analysis (1)
- 5' UTR (1)
- A-FFIP (1)
- AB-serum (1)
- ABCB1 (1)
- ABCC1 (1)
- ACLF (1)
- ADGRE1 (1)
- ADHD differential diagnosis (1)
- AICAR (1)
- AKT signaling (1)
- ALD (1)
- AML – acute myeloid leukemia (1)
- AMPK (1)
- APRI (1)
- ASAP (1)
- ASD-specific (1)
- AU-rich element (1)
- Acute Myeloid Leukemia (1)
- Addison’s disease (1)
- Adenocarcinoma (1)
- Adenylyl cyclase (1)
- Adhesion (1)
- Adverse drug reaction (1)
- Ag-RDT (1)
- Aging (1)
- Akaike information criterion (AIC) (1)
- Allergic asthma (1)
- Amitriptyline (1)
- Amniotic fluid (1)
- Anal cancer (1)
- Anesthesia, Intravenous (1)
- Aneurysms (1)
- Animal wings (1)
- Anosmia (1)
- Anterior cruciate ligament reconstruction (1)
- Anticholinergic (1)
- Anticoagulant therapy (1)
- Anticoagulants [MeSH] (1)
- Anticoagulation (1)
- Antiplatelet therapy (1)
- Antiretroviral therapy (1)
- Antiviral therapy (1)
- Anxiety (1)
- Aortic stiffness (1)
- Arms (1)
- Aromatase Inhibitors (1)
- Ascites (1)
- Aspergillus fumigatus (1)
- Aspergillus species (1)
- Ataxia-telangiectasia (1)
- Atherosclerosis (1)
- Atm (1)
- Atrial fibrillation (1)
- Attention-deficit / hyperactivity disorder (1)
- Attitude (1)
- Audio equipment (1)
- Audio signal processing (1)
- Audiology (1)
- Aurora A (1)
- Australia (1)
- Autism (1)
- Autism spectrum disorder (1)
- Automated Tube Potential Selection (1)
- Automatic Environmental Tobacco Smoke Emitter (1)
- B cell subpopulations (1)
- B-cell antigen receptor (1)
- B.1.1.7 (1)
- B.1.617.1 (1)
- B.1.617.2 (1)
- BIRC5 (1)
- BMNC (1)
- BNT2b2 (1)
- BPO (1)
- BRAF (1)
- BRUCE (1)
- Bayesian inference (1)
- Bee venom allergy (1)
- Benefit (1)
- Bibliometric analysis (1)
- Big five (1)
- Birth (1)
- Bleeding (1)
- Blood groups (1)
- Blood plasma (1)
- Bloodstream infections (1)
- Body limbs (1)
- Bone marrow (1)
- Borrelia miyamotoi (1)
- Bradycardia (1)
- Bright light therapy (1)
- Bronchial inflammation (1)
- C. elegans (1)
- CAD/CAM (1)
- CD19 (1)
- CD271 (1)
- CD3/CD19 depletion (1)
- CD36 (1)
- CD41 (1)
- CD45RA naïve lymphocytes (1)
- CD62P (1)
- CD74 (1)
- CD8+ T lymphocytes (1)
- CD8+ tumor infiltrating lymphocytes (1)
- CDK2 (1)
- CHA2DS2-VASc-score (1)
- CPE (1)
- CPT1A (1)
- CRISPR/Cas9 (1)
- CRM (1)
- CRM1 (1)
- CRP (1)
- CRPC (1)
- CSC marker (1)
- CT pulmonary angiography (1)
- CT radiation exposure (1)
- Caco-2 cells (1)
- Canada (1)
- Cancer (1)
- Cancer Staging (1)
- Cancer detection and diagnosis (1)
- Cannabis (1)
- Carcinoma, Ductal, Breast (1)
- Cardiovascular epidemiology (1)
- Cardiovascular magnetic resonance (1)
- Case management (1)
- Case management [MeSH] (1)
- Cell distribution (1)
- Cell motility (1)
- Cell signalling (1)
- Cell staining (1)
- Cellular stress responses (1)
- Central nervous system (1)
- Cerebrospinal fluid (1)
- Chemoradiotherapy (1)
- Child adiposity (1)
- Chondral Lesion (1)
- Chronic disease [MeSH] (1)
- Chronic hepatitis (1)
- Chronic intestinal failure (1)
- Chronic kidney disease (1)
- Citation (1)
- Clincial pharmacology (1)
- Co-morbidity (1)
- Cognitive impairment (1)
- Cognitive neurology (1)
- Colchicum (1)
- Cold hardiness (1)
- Cold tolerance (1)
- Colorectal cancer (1)
- Computed axial tomography (1)
- Computed tomography pulmonary angiography (CTPA) (1)
- Computer hardware (1)
- Computer software (1)
- Computers (1)
- Conservative treatment (1)
- Constrained posture (1)
- Coronary artery disease (1)
- Cost-effectiveness analysis (1)
- Cre-recombinase (1)
- Critical care (1)
- Cryptococcus (1)
- CspA (1)
- CspZ (1)
- Cyp46a1 (1)
- Cytogenetics (1)
- Cytoplasm (1)
- Cytoplasmic staining (1)
- Cytoreductive nephrectomy (1)
- Cytoskeletal proteins (1)
- D-dimer (1)
- DBS (1)
- DC-NK cell interaction (1)
- DHA (1)
- DNA Damage (1)
- DNA damage (1)
- DNA damage response (1)
- DNA-binding proteins (1)
- DOMS (1)
- DST (1)
- Data processing (1)
- Data science (1)
- Deletion mutation (1)
- Dengue (1)
- Dengue fever (1)
- Density equalizing (1)
- Dental education (1)
- Dental implants (1)
- Dental phobia (1)
- Dental practice (1)
- Dental students (1)
- Dental training (1)
- Diabetes mellitus (1)
- Diagnostic error (1)
- Diagnostic markers (1)
- Digestive system procedures (1)
- Digital workshops (1)
- Disabilities (1)
- Discs large (1)
- Distance to water (1)
- Distribution limits (1)
- Double-blind placebo-controlled trial (1)
- Drug susceptibility testing (1)
- Drug therapy (1)
- Dual-Source CT (1)
- D’Amico classification (1)
- ECMO (1)
- EGFR (1)
- EGFRvIII mutation (1)
- EMR1 (1)
- EPA (1)
- ERK3/MAPK6 (1)
- ERM (1)
- Early intervention (1)
- Economic analysis (1)
- Economic benchmarks (1)
- Education (1)
- Elderly (1)
- Elevation (1)
- Ellipsoids (1)
- Emotional recognition (1)
- Emotions (1)
- EndMT (1)
- Endocrine cancer (1)
- Endometriosis (1)
- Endothelial cell (EC) (1)
- Endothelial cells (1)
- England (1)
- Enterobacterales (1)
- Enterobacteriaceae (1)
- Enzyme regulation (1)
- Epidemiology (1)
- Epidermal growth factor receptor (1)
- Epidural abscess (1)
- Epidural block (1)
- Epileptic seizures (1)
- Epsilon (1)
- Ergonomics (1)
- Erythropoiesis (1)
- Estrogen Receptor Modulators (1)
- Etiology (1)
- Evidence based medicine (1)
- Evidence-based dentistry (1)
- Evidence-based medicine (1)
- Exercise (1)
- Exercise challenge (1)
- Exercise-induced asthma (1)
- Exhaled nitric oxide (1)
- Extracorporeal membrane oxygenation (1)
- Exudates and transudates (1)
- F4/80 (1)
- FFLU (1)
- FFPE (1)
- FIB-4 (1)
- FOXO3 (1)
- FOXO3a (1)
- Factor H (1)
- Factor analysis (1)
- Feasibility studies (1)
- Feedback (1)
- Fevers (1)
- Finevo (1)
- Five-Konzept (1)
- Flow cytometry (1)
- Forced expiratory volume in 1 s (1)
- Forensics (1)
- Francisella tularensis (1)
- Francisella tularensis subspecies holarctica (1)
- Functional clustering (1)
- Functional electrical stimulation (1)
- Functional mitral regurgitation (1)
- Fusarium (1)
- GABA (1)
- GMP (1)
- GPR4 (1)
- GRK2 (1)
- GSK3α (1)
- GSK3β (1)
- Gait analysis (1)
- Galleria mellonella (1)
- Gastric cancer (1)
- Gastrointestinal tract (1)
- Gender analysis (1)
- Gene prediction (1)
- General dental practice (1)
- Genetics (1)
- Genome annotation (1)
- Geographically weighted regression (GWR) (1)
- German people (1)
- Germany (1)
- Gestational diabetes (1)
- Gleason Score (1)
- Gleason score (1)
- Gleason upgrading (1)
- Glioblastoma (1)
- Global health (1)
- Glucose Transporter Type 1 (1)
- Goserelin (1)
- Gram negative bacteria (1)
- GvHD (1)
- HBV (1)
- HBV reactivation (1)
- HCC (1)
- HCV treatment (1)
- HLA class II (1)
- HLA peptidome (1)
- HNSCC (1)
- HOD (1)
- HODE (1)
- HOLEP (1)
- HPV (1)
- HSCT (1)
- HSV (1)
- HSV-1 (1)
- HSV-2 (1)
- HUVEC (1)
- Hashimoto’s thyroiditis (1)
- HbA1c (1)
- HeLa cells (1)
- Health care (1)
- Health economics (1)
- Health services research [MeSH] (1)
- Heart failure (1)
- Hedgehog (1)
- Hematopoietic stem cell transplantation (1)
- Hepatitis C virus (1)
- Hip (1)
- Histology (1)
- Hmox1 (1)
- HoLEP (1)
- Hodgkin lymphoma (1)
- Hospitals (1)
- Hsp90 inhibitor (1)
- HuR (1)
- Human (1)
- Human olfaction (1)
- Hydrocephalus (1)
- Hymenoptera venom immunotherapy (1)
- Hypertension (1)
- IFN-β (1)
- IHC (1)
- IKKε (1)
- IL-15 (1)
- IL-18BP (1)
- IL-1β (1)
- IL-21 (1)
- IL-27 cytokine (1)
- IL-33 (1)
- IL-6 (1)
- INR (1)
- IPS e.max system (1)
- IPSS (1)
- IRES translation (1)
- ISR (1)
- Image analysis (1)
- Immune cells (1)
- Immune suppression (1)
- Immunohistochemistry techniques (1)
- Immunology (1)
- Impella (1)
- Imrt (1)
- IncL (1)
- IncX (1)
- Incidence rate (1)
- Induced sputum (1)
- Infarction (1)
- Infectious disease epidemiology (1)
- Inferior vena cava thrombus (1)
- Inflammatory diseases (1)
- Injury Severity Score (ISS) (1)
- International normalized ratio (1)
- Internet (1)
- Intersectoral care (1)
- Interspecific competition (1)
- Intervention development (1)
- Intestinal failure-associated liver disease (1)
- Intravenous injections (1)
- Ireb2 (1)
- Iron Overload (1)
- Iron chelation (1)
- Joint loading (1)
- Jumping (1)
- K-homology RNA-binding domain (1)
- KAP (1)
- KCNQ1 (1)
- KPS (1)
- Kappa (1)
- Karyotypes (1)
- Keap1-Nrf2 (1)
- Ketogenic Diet (1)
- Ki-67 (1)
- Kidney transplant recipients (1)
- Kinematic posture analysis (1)
- Knowledge (1)
- Kupffer cells (1)
- Kynurenine (1)
- LAMTOR2 (1)
- LC3 I/II (1)
- LCH (1)
- LC–MS/MS (1)
- LDL (1)
- LIR interaction, (1)
- LIVIN (1)
- LM11A 31 (1)
- LQTS (1)
- Laboratory techniques and procedures (1)
- Lafora disease (1)
- Langerhans cell histiocytosis (1)
- Lecture (1)
- Left hemisphere (1)
- Leigh syndrome (1)
- Light sheet fluorescence microscopy (1)
- Linear regression analysis (1)
- Liver fibrosis (1)
- Liver transplantation (1)
- Livestock (1)
- LncRNA - long noncoding RNA (1)
- Local climate (1)
- Longchain polyunsaturated fatty acids (1)
- Luciferase (1)
- Lyme disease (1)
- Lymphangioleiomyomatosis (1)
- Lymphoma (1)
- M. Intracellulare (1)
- M. avium (1)
- M. avium complex (1)
- M. chimaera (1)
- MAGGIC score (1)
- MAIT cell (1)
- MCAO (1)
- MCI (1)
- MEDIC (1)
- MEIS (1)
- MEIS2 (1)
- MMP14 (1)
- MMP2 (1)
- MRI (1)
- MRI patterns of gliomas (1)
- MRP4 (1)
- Machine learning (1)
- Machine learning algorithms (1)
- Machine-learning (1)
- Mammalian target of rapamycin (1)
- Mapping (1)
- Marker genes (1)
- Mastoiditis (1)
- Mechanisms of disease (1)
- Meckel’s diverticulum (1)
- Medical communication (1)
- Medical ethics (1)
- Medical research (1)
- Medical traineeship (1)
- Medication changes (1)
- Medicine and health sciences (1)
- Membrane staining (1)
- Meta-analysis (1)
- Metabolism, Inborn Errors (1)
- Metalloproteases (1)
- Metastasis (1)
- Metastatic renal cell carcinoma (1)
- Metastatic tumors (1)
- Methods (1)
- Michael acceptor (1)
- Micro-CT (1)
- Microalgae (1)
- Microglial cells (1)
- Microphones (1)
- MitraClip (1)
- Molecular medicine (1)
- Molecular neuroscience (1)
- Monocytes and macrophages (1)
- Monosaccharide Transport Proteins (1)
- Morphometry (1)
- Mortality (1)
- Mucomaix® matrix (1)
- Multi-modal feedback (1)
- Multidetector Computed Tomography (1)
- Multimedication (1)
- Multiplate (1)
- Multiple chronic conditions (1)
- Multiple-indication review (1)
- Musculoskeletal mechanics (1)
- Mycobacteria (1)
- Mycobacterium avium complex (1)
- Myocardial perfusion (1)
- Myocardial revascularization (1)
- Myocardial segmentation (1)
- Myocarditis (1)
- N2 (1)
- N501Y (1)
- NADPH oxidase 4 (1)
- NDBI (1)
- NF-ĸB (1)
- NF-κB pathway (1)
- NF-кB (1)
- NIRS (1)
- NK cell (1)
- NK receptors (1)
- NK-92 (1)
- NKT cell (1)
- NLRP3 inflammasomes (1)
- NS3 protease inhibitor (1)
- NTM (1)
- Native T1 mapping (1)
- Necrosis (1)
- Negative staining (1)
- Nek1 (1)
- Neoplasms (1)
- Neuroendocrine cancer (1)
- Neuroimaging (1)
- Neurons (1)
- Neuropathic pain (1)
- Neuropsychological testing (1)
- Neuropsychology (1)
- Next-generation sequencing (1)
- Niche differentiation (1)
- Nimotuzumab (1)
- Non-small cell lung cancer (1)
- Non-tuberculous mycobacteria (1)
- Non-urothelial (1)
- Nontuberculous mycobacteria (1)
- Nordic questionnaire (1)
- Notch (1)
- Nrf2 (1)
- OGR1 (1)
- OGTT (1)
- OHIP-G14 (1)
- OHRQoL (1)
- OSA (1)
- OXA-484 (1)
- Obesity (1)
- Older adults (1)
- Olfactory diagnostics (1)
- Opportunistic infections (1)
- Optogenetics (1)
- Oral and maxillofacial surgery (1)
- Oral anticoagulation (1)
- Ordinary least squares (OLS) (1)
- Orthodontist (1)
- OspE (1)
- Osteoarthritis (1)
- Outpatients (1)
- Overwintering (1)
- PBX (1)
- PBX1 (1)
- PD-L1 (1)
- PEI (1)
- PF-06273340 (1)
- PINK1 (1)
- PKA (1)
- PKCε (1)
- PML (1)
- POCT (1)
- PSA (1)
- PTM (1)
- PYGL (1)
- Paediatric research (1)
- Parenteral nutrition (1)
- Parkinson’s disease (1)
- Patellofemoral Joint (1)
- Patient and public Involvement (1)
- Patient education (1)
- Patient knowledge (1)
- Patient participation (1)
- Patient safety (1)
- Patient satisfaction (1)
- Patterns of care (1)
- Peer-feedback (1)
- Per1−/−-mice (1)
- Percutaneous coronary intervention (1)
- Personality (1)
- Pgrmc1 (1)
- Pharm-fMRI (1)
- Pharmacometrics (1)
- Pharyngeal reflex (1)
- Phenotypic plasticity (1)
- Phospholipids (1)
- Phylogenetic analysis (1)
- Physical environment (1)
- Platelet-rich fibrin (1)
- Platelets (1)
- Point-of-care testing (1)
- Poly-Pore (1)
- PolySUMOylation (1)
- Post-traumatic stress disorder (1)
- Practice (1)
- Prediction (1)
- Prevalence (1)
- Primary care (1)
- Primary health care (1)
- Primary health care [MeSH] (1)
- Probability density (1)
- Probability distribution (1)
- Professional dance (1)
- Prostaglandin (1)
- Prostate cancer (1)
- Prosthetic rehabilitation (1)
- Protein translation (1)
- Prototypes (1)
- Psychological stress (1)
- Public and occupational health (1)
- Public health (1)
- Publication (1)
- Publication output (1)
- QbTest® (1)
- Quantitative features (1)
- Quantra (1)
- Quinolinate phosphoribosyltransferase (1)
- Quinolinic acid (1)
- RITA (1)
- RNA (1)
- RNA binding proteins (1)
- RNA chaperone (1)
- RNA extraction (1)
- RNA isolation (1)
- RNA sequencing (1)
- RNA therapeutics (1)
- RNA therapy (1)
- RNA-binding protein (1)
- RNAi and CRISPR screens (1)
- ROC analysis (1)
- Radiation exposure (1)
- Rainfall (1)
- Randomised trial (1)
- Rare Diseases (1)
- Reactive oxygen species (1)
- Regret (1)
- Regulatory networks (1)
- Renal vein thrombus (1)
- Research design (1)
- Resource competition (1)
- Respiratory Syncytial Virus (1)
- Respiratory infections (1)
- Restricted posture (1)
- Ribosomes (1)
- Risk assessment (1)
- Rural area (1)
- Rush protocol (1)
- S1P (1)
- S1P lyase (1)
- S1P1–5 (1)
- S1PR1 (1)
- SARS-COV-2 (1)
- SCA2 (1)
- SENP6 (1)
- SF-36 (1)
- SGPL1 knockout cell line (1)
- SH-SY5Y neuroblastoma cells (1)
- SKALE score (1)
- SLC6a3 (1)
- SLC7A11 (1)
- SMOC1 (1)
- SNORD95 (1)
- ST2L (1)
- STAMPE2 (1)
- STAT3 (1)
- STIR (1)
- SUD (1)
- SUMO (1)
- SUMO chains (1)
- SW480 cells (1)
- Sarcopenia (1)
- Science structure (1)
- Scientists (1)
- Scientometric analysis (1)
- Scientometrics (1)
- Scientometry (1)
- Seattle heart failure model (1)
- Sensory perception (1)
- Sequence alignment (1)
- Sequence motif analysis (1)
- Serum biomarker (1)
- Sholl analysis (1)
- Short bowel syndrome (1)
- Side effects (1)
- Simulated patients (1)
- Skeletal joints (1)
- Slc11a2 (1)
- Slc25a37 (1)
- Smart nebulizer (1)
- Social research (1)
- Social sciences (1)
- Software tool (1)
- Software tools (1)
- Specimen preparation and treatment (1)
- Speech signal processing (1)
- Spinocerebellar ataxia type 2 (1)
- Sport (1)
- Sports and exercise medicine (1)
- Squamous cell carcinoma (1)
- StUbL (1)
- Stakeholder participation (1)
- Statistical analysis (1)
- Statistical data (1)
- Stenotrophomonas maltophilia (1)
- Stereotactic radiosurgery (1)
- Strength training (1)
- Stress and resilience (1)
- Stroke (1)
- Sub-segmentation (1)
- Sub-zero exposure (1)
- Suicide (1)
- Sumatra (1)
- Superoxide (1)
- Surgical and invasive medical procedures (1)
- Surgical education (1)
- Surgical oncology (1)
- Survey (1)
- Surveys (1)
- Survivin (1)
- Systematic reviews (1)
- T cell receptor (1)
- T-cell development (1)
- T-cell receptor (1)
- T-cell receptor (TCR) (1)
- T-lymphocytes (1)
- TACE (1)
- TALE-homdomain protein (1)
- TAPSE (1)
- TBK1 (1)
- TDAG8 (1)
- TGF-β1 (1)
- TGR(mREN2)27 (1)
- TIMP2 (1)
- TLR (1)
- TNF inhibitors (1)
- TNF-α (1)
- TP53 (1)
- TP53-induced glycolysis and apoptosis regulator (1)
- TRIM25 (1)
- TRIMs (1)
- TRPM8 (1)
- TSP-4 (1)
- TURP (1)
- Targeted therapy (1)
- Tet-inducible system (1)
- Tfrc (1)
- Thrombosis (1)
- Thromboxane (1)
- Total hip arthroplasty (1)
- Toxicity (1)
- Transcription (1)
- Transcriptional control (1)
- Translation initiation (1)
- Transportation (1)
- Trk (1)
- TrkC (1)
- Tubers (1)
- Tularemia (1)
- Tumor infiltrating lymphocytes (1)
- ULBP4 (1)
- Ultra microscopy (1)
- Ultra-rush protocol (1)
- Ultrasonic nebulizer (1)
- Umbilical cord (1)
- Uncertainty (1)
- Undergraduate training (1)
- United States (1)
- Urethral cancer (1)
- VIM (1)
- Vacuoles (1)
- Validation (1)
- Validity (1)
- Variant histology (1)
- Vasculogenesis (1)
- Veins (1)
- Vespid venom allergy (1)
- Viral load (1)
- Virtual patients (1)
- Vitamin D deficiency (1)
- Vmem (1)
- Volumetric analysis (1)
- Warburg effect (1)
- Water chemistry (1)
- Western diet (1)
- White blood cells (1)
- Winter survival (1)
- Work shadowing (1)
- Wound healing (1)
- XIAP (1)
- YM155 (1)
- Yellow fluorescent protein (1)
- Zoonosis (1)
- Zoopotentation (1)
- Zooprophylaxis (1)
- Zymosan-induced peritonitis (1)
- academic (1)
- accident (1)
- acetylation (1)
- acetylcholinesterase (1)
- acoustic radiation force impulse imaging (1)
- acquired drug resistance (1)
- actin dynamics (1)
- activities of daily life (1)
- acute inflammation (1)
- acute kidney injury (1)
- acute lung injury (1)
- acute lung injury (ALI) (1)
- acute lymphoblastic leukemia (1)
- acute pain (1)
- acute respiratory distress syndrome (1)
- acute-on-chronic liver failure (1)
- acute-on-chronic liver failure (ACLF) (1)
- adenosine (1)
- adenosine receptors (1)
- adipocytes (1)
- adiponectin (1)
- adipose-derived mesenchymal stem/stromal cells (1)
- adipose-derived stem cells (1)
- adipose-derived stromal/stem cells (1)
- adoptive cancer immunotherapy (1)
- adoptive immunotherapy (1)
- adrenal insuffciency (1)
- adult neurogenesis (1)
- adverse reaction (1)
- affective disorder (1)
- affective disorders (1)
- aged (1)
- ageing (1)
- agent-based models (1)
- air pollution (1)
- airborne bacteria (1)
- albumin (1)
- alcoholic hepatitis (1)
- algorithm (1)
- allergy (1)
- allogeneic stem cell transplantation (1)
- alpha-synuclein (1)
- alpharetroviral vector (1)
- amlexanox (1)
- amyotrophic lateral sclerosis (ALS) (1)
- analgesics (1)
- anaplastic large cell lymphoma (1)
- anemia (1)
- angioedema control test (1)
- angiography (1)
- animal model (1)
- anti-angiogenic therapy (1)
- anti-cancer therapy (1)
- anti-tumor activity (1)
- antiadhesive composites (1)
- antibacterial composites (1)
- antibiotic therapy (1)
- antibodies (1)
- antifibrotic therapy (1)
- antifungal activity (1)
- antifungal combination therapy (1)
- antifungal host response (1)
- antifungal therapy (1)
- antimicrobial stewardship (1)
- antireflux surgery (1)
- antiviral (1)
- antiviral drugs (1)
- apical constriction (1)
- apical junction (1)
- apical polarity (1)
- arachidonate 12/15-lipoxygenase (Alox12/15) (1)
- arachidonate 15-lipoxygenase (1)
- arachidonic acid (1)
- architecture (1)
- aromatics (1)
- articular cartilage (1)
- aspiration (1)
- aspirin (1)
- assembly (1)
- assembly factor (1)
- associative memory (1)
- asthma (1)
- astrocytes (1)
- astrocytoma (1)
- ataxia score (1)
- atopy (1)
- attachment (1)
- attention (1)
- attention deficit hyperactivity disorder (1)
- auditory (1)
- authorship (1)
- autoimmunity (1)
- automatic environmental tobacco smoke emitter (1)
- automatic scene classification (1)
- autopsy (1)
- back scan (1)
- bacterial translocation (1)
- bacterial viability (1)
- bacterium (1)
- ball (1)
- ballet (1)
- basal cell carcinoma (1)
- basilar artery occlusion (BAO) (1)
- best medical treatment (1)
- beta-band activity (1)
- beta-lactamases (1)
- binary search procedure (1)
- bioactive lipids (1)
- bioactivity (1)
- bioavailability (1)
- biofilm (1)
- biologics (1)
- biologization (1)
- biomarkers (1)
- biomolecular analysis (1)
- biopsy (1)
- biopsy naïve (1)
- bladder neck stenosis (1)
- blood concentrates (1)
- blood culture (1)
- blood pressure (1)
- blood-brain barrier (1)
- blow fly (1)
- body mass index (1)
- body posture (1)
- body sway (1)
- body weight distribution (1)
- bone damage (1)
- bone healing (1)
- bone marrow mononuclear cells (1)
- bone tissue (1)
- bone-regeneration (1)
- bone–implant interface (1)
- borrelia mayonii (1)
- brain imaging (1)
- brain infection (1)
- brain phosphorylome (1)
- brain shift (1)
- brain tumor (1)
- brainstem (1)
- burden of disease (1)
- butyrylcholinesterase (1)
- bypass (1)
- cAMP (1)
- cIAP1/2 (1)
- cadherin (1)
- calbindin (1)
- calcitriol (1)
- cancer and drug vulnerabilities (1)
- cancer cell metabolism (1)
- cancer immunobiology (1)
- cancer metastases (1)
- cancer-associated fibroblasts (1)
- cancer-specific survival (1)
- canonical (1)
- car indoor (1)
- carbapenem resistance (1)
- carbon oxides (COx) (1)
- carcinoma (1)
- cardiac differentiation (1)
- cardiac regeneration (1)
- cardiac reprogramming (1)
- cardiomyocyte apoptosis (1)
- cardiomyocyte proliferation (1)
- cardiothoracic surgery (1)
- cardiovascular disease (1)
- case reports (1)
- caspase 8 (1)
- caspase-8 (1)
- castration resistance (1)
- catheter removal (1)
- cdk (1)
- cell adhesion (1)
- cell and focal adhesion (1)
- cell culture (1)
- cell cycle arrest (1)
- cell cycling (1)
- cell fusion (1)
- cell growth (1)
- cell motility (1)
- cell proliferation (1)
- cell survival (1)
- cell survival mechanisms (1)
- cellular reaction (1)
- cellular response (1)
- cellular therapies (1)
- central nervous system (1)
- central spasticity (1)
- centrifugation (1)
- ceramide (1)
- cerebellum (1)
- cerebral imaging (1)
- cerebral radiation necrosis (1)
- chaperone-mediated autophagy (1)
- chaperones (1)
- chelation therapy (1)
- chemokine (1)
- chemokine receptors (1)
- chemoprotection (1)
- chemoradiotherapy (1)
- chemoresistance (1)
- chemotaxis (1)
- chemotherapeutic drug resistance (1)
- chest injury (1)
- chest trauma (1)
- chimeric antigen receptor (1)
- chloroplasts (1)
- cholangiocarcinoma (1)
- cholinesterase (1)
- chronic granulomatous disease (1)
- chronic hepatitis C (1)
- chronic inflammation (1)
- cigarette smoke (1)
- cigarette strength (1)
- citation (1)
- classification (1)
- classification of bone defects (1)
- clinical research (1)
- clinical trial (1)
- clopidogrel (1)
- cluster analysis (1)
- cluster-randomized controlled trial (1)
- cluttering (1)
- coagulation (1)
- cochlear implants (1)
- cognitive deficits (1)
- cognitive functions (1)
- cognitively stimulating leisure activities (1)
- collagen (1)
- collagen I (1)
- collagen-based biomaterial (1)
- collagen-based matrix (1)
- collective cell migration (1)
- colon (1)
- colorectal cancer (CRC) (1)
- combined immunodeficiency (1)
- comorbidity (1)
- complex systems (1)
- complexity theory (1)
- complexome profiling (1)
- computational functional genomics (1)
- computational knowledge-discovery (1)
- computational techniques (1)
- confinement (1)
- congenital diaphragmatic hernia (1)
- connective tissue (1)
- connectivity (1)
- contamination (1)
- continuous performance test (1)
- contralateral delay activity (1)
- controlled nuclear import (1)
- cooling period (1)
- coronary (1)
- coronavirus disease 2019 (1)
- cortex, gray matter (1)
- covalent drugs (1)
- crime scene (1)
- critical care (1)
- critical-size defect (1)
- criticality (1)
- cryopreservation (1)
- cuticular hydrocarbons (1)
- cyclin D1 (1)
- cyclin Y (1)
- cyclins (1)
- cyclophosphamide (1)
- cystic fibrosis (1)
- cytarabin (1)
- cytokine storm (1)
- cytokine, angiogenesis (1)
- cytotoxic lymphocytes (1)
- cytotoxicity (1)
- daily activity protocols (1)
- dance teacher (1)
- data repositories (1)
- death rates (1)
- death receptor (1)
- debris (1)
- declaration of tobacco ingredients (1)
- decompensated liver cirrhosis (1)
- deep sedation (1)
- deferred treatment (1)
- delayed treatment (1)
- delta (1)
- dementia (1)
- demineralized bone matrix (1)
- dendrite morphogenesis (1)
- density equalizing mapping (1)
- dental assistant (1)
- dental health professional (1)
- desensitization (1)
- development (1)
- dexamethasone (1)
- diabetes (1)
- diabetes mellitus (1)
- diabetes therapy (1)
- diagnostics (1)
- diet (1)
- differentiated thyroid carcinoma (1)
- diffusion tensor imaging (1)
- digital age determination (1)
- dihydrocannabidiol (1)
- dihydroceramides (1)
- dimethylfumarate (1)
- diphtheria toxin (1)
- direct-acting antivirals (1)
- discoidin domain-containing receptor (1)
- disease-free survival (1)
- disordered iron metabolism (1)
- dissemination (1)
- diuretics (1)
- dog study (1)
- dopamine transporter (1)
- doublecortin (1)
- downgrading (1)
- doxycycline (1)
- drug (1)
- drug screening (1)
- drug–drug interactions (1)
- drug–gene interactions (1)
- drug–g–gene interactions (1)
- dual antiplatelet therapy (1)
- dynamic causal modeling (1)
- dysphagia (1)
- eNPP2 (1)
- early continence (1)
- early detection (1)
- early loss (1)
- early onset (1)
- ectopic pregnancy (1)
- efferocytosis (1)
- efficacy (1)
- eicosanoids (1)
- electrode design (1)
- electron transfer (1)
- electrophilic fatty acids (1)
- electrophysiology (1)
- eligibility (1)
- elite athletes (1)
- eltrombopag (1)
- emergency care (1)
- emergent self-organizing maps (1)
- endocannabinoids (1)
- endoplasmic reticulum (1)
- endothelial cell (1)
- endothelial nitric-oxide synthase (1)
- endourology (1)
- endovascular treatment (1)
- enterobacter infections; pseudomonas aeruginosa; epidemiology (1)
- entomological evidence (1)
- epidemics (1)
- epidermis (1)
- epigenetics (1)
- epileptic encephalopathies (1)
- epithelial-to-mesenchymal transition (EMT) (1)
- erastin (1)
- essential tremor (1)
- euthymic (1)
- everolimus (1)
- everyday life (1)
- ex vivo expansion (1)
- ex-Gaussian analysis (1)
- experimental pain models (1)
- expertise (1)
- exponential model (1)
- extracellular matrix (1)
- face-name association task (1)
- factor H (1)
- falls (1)
- false memory (1)
- fatigue (1)
- feeder cells (1)
- female health (1)
- ferroportin (1)
- ferroptosis (1)
- fibrinolysis (1)
- fibrosis (1)
- fibrotest (1)
- fingolimod (1)
- first-line chemotherapy (1)
- fitness (1)
- fixed partial dentures (1)
- follow-up (1)
- forensics (1)
- fractional anisotropy (1)
- fractionation (1)
- fragile-X-associated tremor-ataxia syndrome (1)
- frequency of attacks (1)
- fresh frozen plasma (1)
- fronto-temporal lobar dementia (1)
- fronto-temporal-lobar-dementia (1)
- full-contour crown restorations (1)
- function (1)
- functional connectivity (1)
- functional magnetic resonance imaging (1)
- fundoplication (1)
- fungi (1)
- fungus (1)
- gadolinium enhancing lesion (1)
- galactomannan (1)
- gastroesophageal reflux (1)
- gender differences (1)
- gene expression analysis (1)
- gene signature (1)
- gene therapy (1)
- general anaesthesia (1)
- general practitioner (1)
- genetic diversity (1)
- genetic predisposition (1)
- genetics (1)
- geriatric patients (1)
- glial activation (1)
- glioma microenvironment (1)
- glucose metabolism (1)
- glycolysis (1)
- glycoproteins (1)
- graft-versus-host disease (1)
- graft-versus-tumor effect (1)
- granulomas (1)
- granulomatous inflammation (1)
- graph theory (1)
- growth inhibition (1)
- haploidentical (1)
- head and neck squamous cell carcinoma (1)
- head-and-neck cancer (1)
- healthcare workers (1)
- heart failure (1)
- heat (1)
- heat stress (1)
- hedgehog signaling (1)
- hedgehog signaling pathway (1)
- hematopoiesis (1)
- hematopoietic cell transplantation (1)
- hematopoietic stem and progenitor cells (1)
- hematopoietic stem cell transplantation (1)
- hemorrhagic transformation (1)
- hepatic steatosis (1)
- hepatic stellate cells (1)
- hepatitis B virus (1)
- hepatitis C virus (1)
- hepatitis E virus (1)
- hepatoblastoma (1)
- hepatocellular cancer (1)
- hereditary angioedema (1)
- heterogeneity (1)
- high molecular weight plasticizer (1)
- high throughput (1)
- high-dimensional data sets (1)
- high-throughput nucleotide sequencing (1)
- hippocampus (1)
- histological outcomes (1)
- histomorphometry (1)
- histone deacetylase (1)
- home visit (1)
- homeodomain protein (1)
- host cell interaction (1)
- host cell response (1)
- host-pathogen interaction (1)
- host-targeting antivirals (1)
- hostpathogen interaction (1)
- human Natural Killer cell (1)
- human antigen R (HuR) (1)
- human cytomegalovirus (1)
- human decellularized dermis (1)
- human subjects (1)
- humans (1)
- humectant agents (1)
- hybrid abutment (1)
- hydrogen peroxide (1)
- hyperglycemia (1)
- hyperlipidemia (1)
- hypoxia-induced cell death (1)
- hypoxia-inducible factor (1)
- idiopathic dystonia (1)
- image analysis (1)
- image-guided tissue acquisition (1)
- immune cells (1)
- immune checkpoint (1)
- immune defense (1)
- immune deficiency (1)
- immune host defense (1)
- immune infiltration (1)
- immune response (1)
- immunoglobulin superfamily (1)
- immunological research (1)
- immunosuppressive agent (1)
- immunosuppressive drug (1)
- in vitro models (1)
- in vivo dosimetry (1)
- in-cabin exposure (1)
- indoor air pollution (1)
- induced membrane (1)
- inducible gene expression (1)
- inducible nitric oxide synthase (1)
- inertial motion capture (1)
- infection control (1)
- infection model (1)
- infectivity (1)
- infiltration (1)
- inhibitor (1)
- inhibitor of apoptosis protein family (1)
- inhibitors (1)
- inosine (1)
- inositol signaling (1)
- insertion (1)
- insulin resistance (1)
- insurance data (1)
- integration (1)
- interferon (1)
- interferon type III (1)
- interleukin-1 (1)
- interleukin-18 (1)
- interleukin-22 (1)
- internal ribosomal entry site (IRES) (1)
- internet (1)
- interstitial multicatheter brachytherapy (1)
- intervention study (1)
- intestinal barrier (1)
- intoxication (1)
- intravenous iron therapy (1)
- intrinsic apoptosis (1)
- intrinsic drug resistance (1)
- invasive fungal infection (1)
- invasive growth (1)
- inverse stage migration (1)
- inflammation (1)
- ionomycin (1)
- iron chelation (1)
- iron chelator (1)
- iron chelators (1)
- iron deficiency anemia (1)
- iron homeostasis (1)
- iron overload versus deprivation (1)
- iron-trafficking (1)
- isocaloric ketogenic diet (1)
- jejunoileal atresia (1)
- joint contact forces (1)
- junctional adhesion molecule (1)
- juvenile myoclonic epilepsy (1)
- keratinocytes (1)
- kinematics (1)
- knee adduction moment (1)
- laceration (1)
- lentiviral vector (1)
- leukemia (1)
- leukocytes (1)
- leukopenia (1)
- levetiracetam (1)
- lichen extracts (1)
- light irradiation (1)
- linoleic acid metabolites (1)
- lipid mediator (1)
- lipid metabolism (1)
- lipids (1)
- lipids inflammatory pain (1)
- lipofuscin (1)
- lipopolyplex (1)
- lipoxin A4 (1)
- liquid PRF (1)
- liquid-PRF (1)
- live cell imaging (1)
- live/dead staining (1)
- liver X receptor (1)
- liver cirrhosis (1)
- liver disease (1)
- liver injury (1)
- liver steatosis (1)
- lncRNA (1)
- local control (1)
- local recurrence (1)
- location (1)
- locator (1)
- long-term follow-up (1)
- long-term potentiation (1)
- long-term prophylaxis (1)
- longevity (1)
- low speed centrifugation concept (1)
- low-dose imaging (1)
- lung (1)
- lung disease (1)
- luteolin (1)
- lymphangiogenesis (1)
- lymphocyte (1)
- mGluR3 (1)
- mGluR5 (1)
- mRNA stability (1)
- mRNA1273 (1)
- mTOR inhibition (1)
- mTORC1 (1)
- machine learning (ML) (1)
- machine-learning (1)
- magnetoencephalography (1)
- major depression (1)
- major depression (MD) (1)
- major depressive disorder (1)
- major depressive disorder (MDD) (1)
- malignancy (1)
- malignant glioma (1)
- mammary cancer (1)
- mammary carcinoma (1)
- markovianity (1)
- mass spectrometry (1)
- mast cells (1)
- maternal tobacco smoke (1)
- mathematical modeling (1)
- matrix metalloproteinase (1)
- matrix metalloproteinases (1)
- mean diffusivity (1)
- mechanism of action (1)
- medical error (1)
- medical risk factors (1)
- medication (1)
- medication review (1)
- medulloblastoma resection (1)
- melanoma (1)
- membrane potential (1)
- membrane-less organelles (1)
- membranous urethral stricture (1)
- memebrane (1)
- memory (1)
- menthol (1)
- merkel cell carcinoma (1)
- mesenchymal stem cell (1)
- mesenchymal stromal cell (1)
- mesenchymal stromal cells (1)
- meta-analysis (1)
- metabolic cancer therapy (1)
- metabolic liver disease (1)
- metabolic syndrome (1)
- metamorphosis (1)
- metastatic colorectal cancer (1)
- metastatic prostate cancer (1)
- metastatic urethral cancer (1)
- metformin (1)
- methacarn (1)
- methylation profiling (1)
- miR (1)
- miR-122 (1)
- miR-142-3p (1)
- miR-21 (1)
- miR-375 (1)
- mice (1)
- microbiome (1)
- microenvironment (1)
- microglia (1)
- microlesions (1)
- microsatellite instability (1)
- microtubular cytoskeleton (1)
- middle-aged (1)
- migration and invasion (1)
- mitochondrial disease (1)
- mobile air quality study (1)
- mold (1)
- molecular surveillance (1)
- monoclonal antibodies (1)
- monocyte chemotactic protein 1 (MCP-1) (1)
- monotype abutment (1)
- monsoon (1)
- morbidity (1)
- morphogenesis (1)
- morphometry (1)
- mortality analysis (1)
- motility (1)
- motor functions (1)
- mouse model (1)
- movement disorders (1)
- mpMRI (1)
- mtor (1)
- mucormycete (1)
- mucosal inflammation (1)
- multi-scale models (1)
- multidrug resistance (1)
- multifocal (1)
- multimorbidity (1)
- multisensory integration (1)
- multivoxel pattern analysis (1)
- musculoskeletal disorders (1)
- musculoskeletal inflammation (1)
- musculoskeletal modeling (1)
- musculoskeletal pain (1)
- musculoskeletal system (1)
- myelodysplastic syndrome (1)
- myeloid cells (1)
- natural cytotoxicity (1)
- natural killer T cells (1)
- natural selection (1)
- naturalistic sample (1)
- ncRNA (1)
- neonate (1)
- nerve-sparing (1)
- network (1)
- neurexin (1)
- neuroimaging (1)
- neuronal avalanches (1)
- neuronal maturation (1)
- neuropsychological impairment (1)
- neurotrophins (1)
- next generation sequencing (1)
- next-generation sequencing (1)
- nitroalkylation (1)
- nitrogen oxides (NOx) (1)
- nodular sclerosis (1)
- noise intervention measures (1)
- non-aneurysmal SAH (1)
- non-canonical (1)
- non-classical adhesion molecule (1)
- non-coding RNA (1)
- non-invasive fibrosis assessment (1)
- non-linear dynamics (1)
- non-malignant hematological diseases (1)
- non-sensory bias (1)
- nonnucleoside polymerase inhibitor (1)
- nucleolus (1)
- nucleoredoxin (1)
- nucleotide metabolism (1)
- nursery schools (1)
- nutrient deprivation (1)
- nutrient endocytosis (1)
- occupational factors (1)
- older people (1)
- olfactory testing (1)
- omega-3 fatty acids (1)
- oncogenes (1)
- oncogenic signaling (1)
- one health (1)
- open field behavior (1)
- open-source (1)
- oral health (1)
- oral health burden (1)
- ordinary differential equations (ODE) (1)
- organisation of health services (1)
- organophosphate flame retardants (OFR) (1)
- organotypic culture (1)
- orientation (1)
- orthodontist (1)
- osteogenic sarcoma cells (1)
- ostium (1)
- ouabain (1)
- outside-in signaling (1)
- overall survival (1)
- overdenture (1)
- oxaliplatin (1)
- p-eIF2α (1)
- p14 (1)
- p21Cip1/CDKN1A (1)
- p47phox (1)
- p53 (1)
- p62 (1)
- p75 (1)
- paediatric (1)
- pain genetics (1)
- pain intensity (1)
- pain medication (1)
- particle size distribution (1)
- particulate matter (PM) (1)
- passive smoke (1)
- pathogen (1)
- patient blood management (1)
- patient preference (1)
- patient safety (1)
- patients' experience (1)
- patient’s decree (1)
- pediatric (1)
- pediatric epilepsy (1)
- pentose phosphate pathway (1)
- perineurium (1)
- perio-prosthetic joint infection (1)
- peritoneal macrophages (1)
- peritumoral edema (1)
- peritumoral edema zone (1)
- peroxisome proliferator-activated receptor (1)
- phage display (1)
- phagocytosis (1)
- pharmacist (1)
- pharmacodynamics (1)
- pharmacoepigenetics (1)
- pharmacogenetics (1)
- pharmacogenomics (1)
- pharmacokinetics (1)
- pharmacological data science (1)
- pharmacological plasticity (1)
- pharmacoresistance (1)
- phenoconversion (1)
- phenylephrine (1)
- phosphatases (1)
- pig (1)
- pilot study (1)
- pitch (1)
- pitch perception (1)
- placenta (1)
- planimetric measurement (1)
- plasma (1)
- plasminogen (1)
- platelet lysate (1)
- platelet-rich fibrin (1)
- platelet-rich-fibrin (1)
- platelets (1)
- point of care (1)
- point shear wave elastography (1)
- polarization (1)
- polo-like kinase 3 (1)
- poly(A)-tail (1)
- polyethylenimine (1)
- polymerase chain reaction (1)
- polyomavirus (MCPyV) (1)
- polypharmacy (1)
- polyunsaturated fatty acid (1)
- porcine (1)
- portal hypertension (1)
- post-exercise hypotension (1)
- post-transcriptional regulation (1)
- post-translational modifications (1)
- posterior circulation (1)
- posterior fossa masses (1)
- posterior fossa tumor (1)
- postmonsoon (1)
- postnatal neurogenesis (1)
- postoperative delirium (1)
- posttranslational modification (1)
- potassium channel (1)
- ppi1 (1)
- pre-emptive allogeneic hematopoietic stem cell transplantation (1)
- pre-professional (1)
- preconditioning (1)
- prediabetes (1)
- predictive coding (1)
- pretreatment (1)
- prevention (1)
- primary health care (1)
- primary prostate cancer (1)
- production (1)
- professional dance (1)
- prognosis (1)
- prognostic marker (1)
- progressive myoclonus epilepsy (1)
- prostaglandins (1)
- prostate neoplasm (1)
- proteasome (1)
- protein complexes (1)
- protein phosphorylation (1)
- protein–protein interaction (1)
- proton density (1)
- proton pump inhibitors (1)
- proton pumping (1)
- proton-sensing GPCR (1)
- proximal tubule cells (1)
- pseudomonas aeruginosa (1)
- psoriatic arthritis (1)
- psychological distress (1)
- pteridine (1)
- publication output (1)
- pulse-spreading harmonic complex (1)
- qPCR (1)
- qRT-PCR detection (1)
- qualitative research (1)
- quantitative magnetic resonance imaging (1)
- quantitative proteomics (1)
- quantum biology (1)
- quantum neurobiology (1)
- quiescence (1)
- radiation (1)
- radiation dosage (1)
- radiation dosimetry (1)
- radiation protection (1)
- radiation-induced (1)
- radical oxygen species (1)
- radical prostatecomy (1)
- radioimmunotherpay (1)
- radiosensitization (1)
- radiotherapy (1)
- radiotherapy resistance (1)
- radixin (1)
- rapamycin (1)
- rat (1)
- rat femur critical size defect (1)
- real-world data (1)
- recovery (1)
- red blood cells (1)
- reference values (1)
- regenerative medicine (1)
- regenerative therapy (1)
- regorafenib (1)
- regorafenib csf concentration (1)
- regulatory T helper cells (1)
- relaxometry (1)
- remodeling (1)
- renal failure (1)
- repeat biopsy (1)
- reperfusion injury (1)
- reproduction biology (1)
- resistance (1)
- resolution (1)
- resolution of inflammation (1)
- respiratory failure (1)
- rest period (1)
- resting‐state (1)
- reverberation (1)
- rheumatoid arthritis (1)
- ribavirin (1)
- risk factor (1)
- risk management (1)
- room simulation (1)
- rosetting T cells (1)
- rotational thromboelastometry (1)
- running (1)
- salvage mastectomy (1)
- sarcopenia (1)
- schizophrenia spectrum (1)
- sciatic nerve (1)
- scoping review (1)
- screening (1)
- screening routine (1)
- screening test (1)
- searchlight analysis (1)
- secondary cancer (1)
- secondary data analysis (1)
- secretome (1)
- segmentation (1)
- seizures (1)
- selectin (1)
- selective autophagy receptor (1)
- selfish genetic element (1)
- semiquinone (1)
- sensory organ development (1)
- sepsis (1)
- serum (1)
- severe acute respiratory syndrome coronavirus 2 (1)
- severe congenital neutropenia (1)
- severely injured (1)
- shedding (1)
- short bowel (1)
- short linear motifs (SLiMs) (1)
- siRNA delivery (1)
- siRNA/RNAi (1)
- sickle cell anemia (1)
- signal transducer and activator of transcription-1 (1)
- signaling (1)
- silk fibroin (1)
- simulation (1)
- simulation training (1)
- single-sided deafness (1)
- sirtuin1 (1)
- size of cigarettes (1)
- skin diseases (1)
- small bowel (1)
- smoking in pregnancy (1)
- socio-economic influences (1)
- soluble MICA (1)
- sonic hedgehog signaling (1)
- sorafenib (1)
- sound analyses (1)
- spatial (1)
- spatial learning (1)
- specialized pro-resolving lipid mediators (SPMs) (1)
- species differences (1)
- speech perception (1)
- sphinganine 1-phosphate (1)
- sphingolipid (1)
- sphingolipids (1)
- sphingosine 1-phoshate (1)
- sphingosine 1-phosphate antagonistst/inhibitors (1)
- sphingosine 1-phosphate metabolism (1)
- sphingosine 1-phosphate signaling (1)
- sphingosine kinase (1)
- spike mutation (1)
- spinal infection (1)
- spirochete (1)
- splicing (1)
- split-mouth (1)
- sport (1)
- spreading (1)
- statin treatment (1)
- statistical parametric mapping (1)
- steatosis (1)
- stem cell niche (1)
- stem cell transplantation (1)
- stem cells (1)
- sterol regulatory element binding protein-2 (1)
- stoma (1)
- stress granules (1)
- stress period (1)
- stretching (1)
- structure (1)
- stuttering (1)
- subcutaneous fat (1)
- subpopulation (1)
- subventricular zone (1)
- success rate (1)
- survival (1)
- survival rate (1)
- swallowing (1)
- symptoms (1)
- synaptic plasticity (1)
- synaptic signaling (1)
- synoviocytes (1)
- synuclein (1)
- systemic inflammation (1)
- t-distributed stochastic neighbor embedding (1)
- tandem mass spectrometry (1)
- targeted biopsy (1)
- tauopathies (1)
- tauopathy (1)
- temozolomide (1)
- temsirolimus (1)
- test protocol (1)
- testosterone (1)
- tetracycline (1)
- tetrahydrocannabinol (1)
- thalassemia (1)
- therapy (1)
- therapy monitoring (1)
- therapy resistance (1)
- thiazolidine and perhydrothiazine derivatives of aldophosphamide and I-aldophosphamide (1)
- thrombectomy (1)
- thrombin (1)
- thrombolysis (1)
- thrombolysis (tPA) (1)
- thrombopenia (1)
- thrombopietin receptor agonist (1)
- thrombosis (1)
- thymic selection (1)
- tick (1)
- tissue mechanics (1)
- tobacco control (1)
- tobacco products (1)
- tobacco taxation (1)
- toc64 (1)
- toll-like receptor (1)
- topical agent (1)
- tractography (1)
- traffic emissions (1)
- trafficking (1)
- training program (1)
- transcription factors (1)
- transcriptional profiling (1)
- transcriptome analysis (1)
- transfer entropy (1)
- transferrin (1)
- transient elastography (1)
- transient receptor potential channels (1)
- transjugular intrahepatic portosystemic shunt (TIPS) (1)
- transketolase-like protein 1 (1)
- translational medical research (1)
- translational study (1)
- translocon (1)
- transmission (1)
- transrectal prostate biopsy (1)
- transverse axis (1)
- trauma registry (1)
- traumaticbraininjury(TBI) (1)
- treatment (1)
- triathlon (1)
- trophoblast organoids (1)
- trophoblastic cell lines (1)
- tumor adhesion (1)
- tumor immune evasion (1)
- tumor metabolism (1)
- tumor migration (1)
- tumor pain (1)
- tumor proliferation (1)
- tumor stroma (1)
- tumor-associated macrophages (TAM) (1)
- type B (1)
- type I interferon (1)
- tyrosine hydroxylase (1)
- tyrosine kinase receptor signaling (1)
- ubiquitin ligase (1)
- ulcerative colitis (1)
- ultrasonic cleaning (1)
- ultrasound (1)
- unconventional T cell (1)
- unilateral hip osteoarthritis (1)
- upgrading (1)
- urethal stricture (1)
- urethroplasty (1)
- ustekinumab (1)
- vaccination (1)
- valproic acid (1)
- vasoconstriction (1)
- vasodilation (1)
- vemurafenib (1)
- ventilation modes (1)
- ventralis intermedius nucleus (1)
- vertical transmission (1)
- vertigo (1)
- vestibular function (1)
- viability (1)
- viral tracing (1)
- virulence (1)
- virus (1)
- vismodegib (GDC-0449) (1)
- vitamin D deficiency (1)
- vitamin D metabolites (1)
- vitamin D receptor (1)
- vocational (1)
- volatile organic compounds (VOC) (1)
- volatile sedation (1)
- waiting time (1)
- walking (1)
- wheezing (1)
- whole-genome sequencing (1)
- wild animals (1)
- workplace health promotion (1)
- wound healing (1)
- xenograft (1)
- zinc protoporphyrin (1)
- zirconia (1)
- ß-D-glucan (1)
- ß-amyloid (1)
- β-lactamases (1)
- γδT cell (1)
- fibrogenesis (1)
- fingolimod (1)
- flow cytometry (1)
Institute
- Medizin (541) (remove)
Background: The aim of this meta-analysis was to evaluate efficacy and safety of first-line chemotherapy with or without a monoclonal antibody in elderly patients ( ≥ 70 years) with metastatic colorectal cancer (mCRC), since they are frequently underrepresented in clinical trials.
Results: Individual data from 10 studies were included. From a total of 3271 patients, 604 patients (18%) were ≥ 70 years (median 73 years, range 70–88). Of these, 335 patients were treated with a bevacizumab-based first-line regimen and 265 were treated with chemotherapy only. The median PFS was 8.2 vs. 6.5 months and the median OS was 16.7 vs. 13.0 months in patients treated with and without bevacizumab, respectively. The safety profile of bevacizumab in combination with first-line chemotherapy did not differ from published clinical trials.
Materials and Methods: PubMed and Cochrane Library searches were performed on 29 April 2013 and studies published to this date were included. Authors were contacted to request progression-free survival (PFS), overall survival (OS) data, patient data on treatment regimens, age, sex and potential signs of toxicity in patients ≥ 70 years of age.
Conclusions: This meta-analysis suggests that the addition of bevacizumab to standard first-line chemotherapy improves clinical outcome in elderly patients with mCRC and is well tolerated.
Myomas, also known as fibroids, are a specific characteristic of the human species. No other primates develop fibroids. At a cellular level, myomas are benign hyperplastic lesions of uterine smooth muscle cells. There are interesting theoretical concepts that link the development of myomas in humans with the highly specific process of childbirth from an upright position and the resulting need for greatly increased “expulsive” forces during labor. Myomas might be the price our species pays for our bipedal and highly intelligent existence. Myomas affect, with some variability, all ethnic groups and approximately 50% of all women during their lifetime. While some remain asymptomatic, myomas can cause significant and sometimes life-threatening uterine bleeding, pain, infertility, and, in extreme cases, ureteral obstruction and death. Traditionally, over 50% of all hysterectomies were performed for fibroids, leading to a significant healthcare burden. In this article, we review the developments of the past 20 years with regard to multiple new treatment strategies that have evolved during this time.
Aim: NADPH oxidases are important sources of reactive oxygen species (ROS). Several Nox homologues are present together in the vascular system but whether they exhibit crosstalk at the activity level is unknown. To address this, vessel function of knockout mice for the cytosolic Nox organizer proteins p47phox, NoxO1 and a p47phox-NoxO1-double knockout were studied under normal condition and during streptozotocin-induced diabetes.
Results: In the mouse aorta, mRNA expression for NoxO1 was predominant in smooth muscle and endothelial cells, whereas p47phox was markedly expressed in adventitial cells comprising leukocytes and tissue resident macrophages. Knockout of either NoxO1 or p47phox resulted in lower basal blood pressure. Deletion of any of the two subunits also prevented diabetes-induced vascular dysfunction. mRNA expression analysis by MACE (Massive Analysis of cDNA ends) identified substantial gene expression differences between the mouse lines and in response to diabetes. Deletion of p47phox induced inflammatory activation with increased markers of myeloid cells and cytokine and chemokine induction. In contrast, deletion of NoxO1 resulted in an attenuated interferon gamma signature and reduced expression of genes related to antigen presentation. This aspect was also reflected by a reduced number of circulating lymphocytes in NoxO1-/- mice.
Innovation and conclusion: ROS production stimulated by NoxO1 and p47phox limit endothelium-dependent relaxation and maintain blood pressure in mice. However, NoxO1 and p47phox cannot substitute each other despite their similar effect on vascular function. Deletion of NoxO1 induced an anti-inflammatory phenotype, whereas p47phox deletion rather elicited a hyper-inflammatory response.
The dentate gyrus (DG) is a unique structure of the hippocampus that is distinguished by ongoing neurogenesis throughout the lifetime of an organism. The development of the DG, which begins during late gestation and continues during the postnatal period, comprises the structural formation of the DG as well as the establishment of the adult neurogenic niche in the subgranular zone (SGZ). We investigated the time course of postnatal maturation of the DG in male C57BL/6J mice and male Sprague-Dawley rats based on the distribution patterns of the immature neuronal marker doublecortin (DCX) and a marker for mature neurons, calbindin (CB). Our findings demonstrate that the postnatal DG is marked by a substantial maturation with a high number of DCX-positive granule cells (GCs) during the first two postnatal weeks followed by a progression toward more mature patterns and increasing numbers of CB-positive GCs within the subsequent 2 weeks. The most substantial shift in maturation of the GC population took place between P7 and P14 in both mice and rats, when young, immature DCX-positive GCs became confined to the innermost part of the GC layer (GCL), indicative of the formation of the SGZ. These results suggest that the first month of postnatal development represents an important transition phase during which DG neurogenesis and the maturation course of the GC population becomes analogous to the process of adult neurogenesis. Therefore, the postnatal DG could serve as an attractive model for studying a growing and functionally maturing neural network. Direct comparisons between mice and rats revealed that the transition from immature DCX-positive to mature CB-positive GCs occurs more rapidly in the rat by approximately 4–6 days. The remarkable species difference in the speed of maturation on the GC population level may have important implications for developmental and neurogenesis research in different rodent species and strains.
The nervous system is a non-linear dynamical complex system with many feedback loops. A conventional wisdom is that in the brain the quantum fluctuations are self-averaging and thus functionally negligible. However, this intuition might be misleading in the case of non-linear complex systems. Because of an extreme sensitivity to initial conditions, in complex systems the microscopic fluctuations may be amplified and thereby affect the system’s behavior. In this way quantum dynamics might influence neuronal computations. Accumulating evidence in non-neuronal systems indicates that biological evolution is able to exploit quantum stochasticity. The recent rise of quantum biology as an emerging field at the border between quantum physics and the life sciences suggests that quantum events could play a non-trivial role also in neuronal cells. Direct experimental evidence for this is still missing but future research should address the possibility that quantum events contribute to an extremely high complexity, variability and computational power of neuronal dynamics.
Invasive fungal infections are still an important cause of morbidity and mortality in immunocompromised patients such as patients suffering from hematological malignancies or patients undergoing hematopoietic stem cell transplantion. In addition, other populations such as human immunodeficiency virus-patients are at higher risk for invasive fungal infection. Despite the availability of new antifungal compounds and better supportive care measures, the fatality rate of invasive fungal infection remained unacceptably high. It is therefore of major interest to improve our understanding of the host–pathogen interaction to develop new therapeutic approaches such as adoptive immunotherapy. As experimental methodologies have improved and we now better understand the complex network of the immune system, the insight in the interaction of the host with the fungus has significantly increased. It has become clear that host resistance to fungal infections is not only associated with strong innate immunity but that adaptive immunity (e.g., T cells) also plays an important role. The antifungal activity of natural killer (NK) cells has been underestimated for a long time. In vitro studies demonstrated that NK cells from murine and human origin are able to attack fungi of different genera and species. NK cells exhibit not only a direct antifungal activity via cytotoxic molecules but also an indirect antifungal activity via cytokines. However, it has been show that fungi exert immunosuppressive effects on NK cells. Whereas clinical data are scarce, animal models have clearly demonstrated that NK cells play an important role in the host response against invasive fungal infections. In this review, we summarize clinical data as well as results from in vitro and animal studies on the impact of NK cells on fungal pathogens.
Immunosuppression is a typical hallmark of cancer and frequently includes perturbations of the NKG2D tumor recognition system as well as impaired signaling by other activating NK cell receptors. Several in vitro studies suggested that sustained engagement of the NKG2D receptor, as it is occurring in the tumor microenvironment, not only impairs expression and function of NKG2D but also impacts signaling by other activating NK receptors. Here, we made use of a transgenic mouse model of ubiquitous NKG2D ligand expression (H2-Kb-MICA mice) to investigate consequences of chronic NKG2D engagement in vivo for functional responsiveness by other activating NK receptors such as NKp46 and Ly49D. Unexpectedly, we found no evidence for an impairment of NKp46 expression and function in H2-Kb-MICA mice, as anticipated from previous in vitro experiments. However, we observed a marked downregulation and dysfunction of the activating receptor Ly49D in activated NK cells from H2-Kb-MICA mice. Ly49D shares the adaptor proteins DAP10 and DAP12 with NKG2D possibly explaining the collateral impairment of Ly49D function in situations of chronic NKG2D engagement. Altogether, our results demonstrate that persistent engagement of NKG2D in vivo, as often observed in tumors, can selectively impair functions of unrelated NK receptors and thereby compromise NK responsiveness to third-party antigens.
Carcinogenesis is a multistep process. Besides somatic mutations in tumor cells, stroma-associated immunity is a major regulator of tumor growth. Tumor cells produce and secrete diverse mediators to create a local microenvironment that supports their own survival and growth. It is becoming apparent that iron acquisition, storage, and release in tumor cells is different from healthy counterparts. It is also appreciated that macrophages in the tumor microenvironment acquire a tumor-supportive, anti-inflammatory phenotype that promotes tumor cell proliferation, angiogenesis, and metastasis. Apparently, this behavior is attributed, at least in part, to the ability of macrophages to support tumor cells with iron. Polarization of macrophages by apoptotic tumor cells shifts the profile of genes involved in iron metabolism from an iron sequestering to an iron-release phenotype. Iron release from macrophages is supposed to be facilitated by ferroportin. However, lipid mediators such as sphingosine-1-phosphate, released form apoptotic tumor cells, upregulate lipocalin-2 (Lcn-2) in macrophages. This protein is known to bind siderophore-complexed iron and thus, may participate in iron transport in the tumor microenvironment. We describe how macrophages handle iron in the tumor microenvironment, discuss the relevance of an iron-release macrophage phenotype for tumor progression, and propose a new role for Lcn-2 in tumor-associated macrophages.
Objective: About 2% of all pregnancies are complicated by the implantation of the zygote outside the uterine cavity and termed ectopic pregnancy. Whereas a multitude of guidelines exists and related research is constantly growing, no thorough assessment of the global research architecture has been performed yet. Hence, we aim to assess the associated scientific activities in relation to geographical and chronological developments, existing research networks and socioeconomic parameters.
Design: Retrospective, descriptive study.
Setting: On the basis of the NewQIS platform, scientometric methods were combined with novel visualising techniques such as density-equalising mapping to assess the scientific output on ectopic pregnancy. Using the Web of Science, we identified all related entries from 1900 to 2012.
Results: 8040 publications were analysed. The USA and the UK were dominating the field in regard to overall research activity (2612 and 723 publications), overall citation numbers and country-specific H-Indices (US: 80, UK: 42). Comparison to economic power of the most productive countries demonstrated that Israel invested more resources in ectopic pregnancy-related research than other nations (853.41 ectopic pregnancy-specific publications per 1000 billlion US$ gross domestic product (GDP)), followed by the UK (269.97). Relation to the GDP per capita index revealed 49.3 ectopic pregnancy-specific publications per US$1000 GDP per capita for the USA in contrast to 17.31 for the UK. Semiqualitative indices such as country-specific citation rates ranked Switzerland first (24.7 citations per ectopic pregnancy-specific publication), followed by the Scandinavian countries Finland and Sweden. Low-income countries did not exhibit significant research activities.
Conclusions: This is the first in-depth analysis of global ectopic pregnancy research since 1900. It offers unique insights into the global scientific landscape. Besides the USA and the UK, Scandinavian countries and Switzerland can also be regarded as leading nations with regard to their relative socioeconomic input.
Being the most aggressive type of brain tumor, glioblastoma is estimated to be diagnosed in about 12,400 new cases in 2017. The diagnosis is dramatic to patients and relatives and leaves open many unanswered questions for them. One is the big question why there is no cure as in other tumors. This review illustrates the US and global research efforts that have been made over the past century. It demonstrates the great magnitude of energy invested by US clinicians and scientists but undoubtedly, more research is needed and funding by NIH and other sources should be continued on the same level.