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Dendritic spines are crucial for excitatory synaptic transmission as the size of a spine head correlates with the strength of its synapse. The distribution of spine head sizes follows a lognormal-like distribution with more small spines than large ones. We analysed the impact of synaptic activity and plasticity on the spine size distribution in adult-born hippocampal granule cells from rats with induced homo- and heterosynaptic long-term plasticity in vivo and CA1 pyramidal cells from Munc-13-1-Munc13-2 knockout mice with completely blocked synaptic transmission. Neither induction of extrinsic synaptic plasticity nor the blockage of presynaptic activity degrades the lognormal-like distribution but changes its mean, variance and skewness. The skewed distribution develops early in the life of the neuron. Our findings and their computational modelling support the idea that intrinsic synaptic plasticity is sufficient for the generation, while a combination of intrinsic and extrinsic synaptic plasticity maintains lognormal like distribution of spines.
The discovery of superconductivity in layered vanadium-based kagome metals AV3Sb5 (A: K, Rb, Cs) has added a new family of materials to the growing class of possible unconventional superconductors. However, the nature of the superconducting pairing in these materials remains elusive. We present a microscopic theoretical study of the leading superconducting instabilities on the kagome lattice based on spin- and charge-fluctuation mediated Cooper pairing. The applied methodology includes effects of both on-site and nearest-neighbor repulsive Coulomb interactions. Near the upper van Hove filling -- relevant for the AV3Sb5 materials -- we find a rich phase diagram with several pairing symmetries being nearly degenerate. In particular, while a substantial fraction of the phase diagram is occupied by a spin-singlet order parameter transforming as a two-dimensional irreducible representation of the point group, several nodal spin-triplet pairing states remain competitive. We compute the band and interaction parameter-dependence of the hierarchy of the leading superconducting instabilities, and determine the detailed momentum dependence of the resulting preferred gap structures. Crucially, for moderate values of the interaction parameters, the individual pairing states depend strongly on momentum and exhibit multiple nodes on the Fermi surface. We discuss the properties of these superconducting gap structures in light of recent experimental developments of the AV3Sb5 materials.
The properties of the outer crust of non-accreting cold neutron stars are studied by using modern nuclear data and theoretical mass tables updating in particular the classic work of Baym, Pethick and Sutherland. Experimental data from the atomic mass table from Audi, Wapstra, and Thibault of 2003 is used and a thorough comparison of many modern theoretical nuclear models, relativistic and non-relativistic ones, is performed for the first time. In addition, the influences of pairing and deformation are investigated. State-of-the-art theoretical nuclear mass tables are compared in order to check their differences concerning the neutron dripline, magic neutron numbers, the equation of state, and the sequence of neutron-rich nuclei up to the dripline in the outer crust of non-accreting cold neutron stars.
We discuss the phase diagram of moderately dense, locally neutral three-flavor quark matter using the framework of an effective model of quantum chromodynamics with a local interaction. The phase diagrams in the plane of temperature and quark chemical potential as well as in the plane of temperature and lepton-number chemical potential are discussed.
We study the effect of neutrino trapping on the phase diagram of dense, locally neutral three-flavor quark matter within the framework of a Nambu--Jona-Lasinio model. In the analysis, dynamically generated quark masses are taken into account self-consistently. The phase diagrams in the plane of temperature and quark chemical potential, as well as in the plane of temperature and lepton-number chemical potential are presented. We show that neutrino trapping favors two-flavor color superconductivity and disfavors the color-flavor-locked phase at intermediate densities of matter. At the same time, the location of the critical line separating the two-flavor color-superconducting phase and the normal phase of quark matter is little affected by the presence of neutrinos. The implications of these results for the evolution of protoneutron stars are briefly discussed. PACS numbers: 12.39.-x 12.38.Aw 26.60.+c
We study the phase diagram of dense, locally neutral three-flavor quark matter within the framework of the Nambu--Jona-Lasinio model. In the analysis, dynamically generated quark masses are taken into account self-consistently. The phase diagram in the plane of temperature and quark chemical potential is presented. The results for two qualitatively different regimes, intermediate and strong diquark coupling strength, are presented. It is shown that the role of gapless phases diminishes with increasing diquark coupling strength.
We study the phase diagram of dense, locally neutral three-flavor quark matter as a function of the strange quark mass, the quark chemical potential, and the temperature, employing a general nine-parameter ansatz for the gap matrix. At zero temperature and small values of the strange quark mass, the ground state of matter corresponds to the color-flavor-locked (CFL) phase. At some critical value of the strange quark mass, this is replaced by the recently proposed gapless CFL (gCFL) phase. We also find several other phases, for instance, a metallic CFL (mCFL) phase, a so-called uSC phase where all colors of up quarks are paired, as well as the standard two-flavor color-superconducting (2SC) phase and the gapless 2SC (g2SC) phase.
Hadron lists based on experimental studies summarized by the Particle Data Group (PDG) are a crucial input for the equation of state and thermal models used in the study of strongly-interacting matter produced in heavy-ion collisions. Modeling of these strongly-interacting systems is carried out via hydrodynamical simulations, which are followed by hadronic transport codes that also require a hadronic list as input. To remain consistent throughout the different stages of modeling of a heavy-ion collision, the same hadron list with its corresponding decays must be used at each step. It has been shown that even the most uncertain states listed in the PDG from 2016 are required to reproduce partial pressures and susceptibilities from Lattice Quantum Chromodynamics with the hadronic list known as the PDG2016+. Here, we update the hadronic list for use in heavy-ion collision modeling by including the latest experimental information for all states listed in the Particle Data Booklet in 2021. We then compare our new list, called PDG2021+, to Lattice Quantum Chromodynamics results and find that it achieves even better agreement with the first principles calculations than the PDG2016+ list. Furthermore, we develop a novel scheme based on intermediate decay channels that allows for only binary decays, such that PDG2021+ will be compatible with the hadronic transport framework SMASH. Finally, we use these results to make comparisons to experimental data and discuss the impact on particle yields and spectra.
We studied oscillatory mechanisms of memory formation in 48 younger and 51 older adults in an intentional associative memory task with cued recall. While older adults showed lower memory performance than young adults, we found subsequent memory effects (SME) in alpha/beta and theta frequency bands in both age groups. Using logistic mixed effect models, we investigated whether interindividual differences in structural integrity of key memory regions could account for interindividual differences in the strength of the SME. Structural integrity of inferior frontal gyrus (IFG) and hippocampus was reduced in older adults. SME in the alpha/beta band were modulated by the cortical thickness of IFG, in line with its hypothesized role for deep semantic elaboration. Importantly, this structure–function relationship did not differ by age group. However, older adults were more frequently represented among the participants with low cortical thickness and consequently weaker SME in the alpha band. Thus, our results suggest that differences in the structural integrity of the IFG contribute not only to interindividual, but also to age differences in memory formation.