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A global synonymical checklist of the species and higher taxa of the insect order Megaloptera is provided. The checklist includes both extant and extinct taxa, and recognizes 2 families, 4 subfamilies, 48 genera, 425 species, and 6 subspecies. Both families (Corydalidae and Sialidae), and three of the four subfamilies (Corydalinae, Chauliodinae, and Sialinae) are known from both extant and extinct species; the Sharasialinae (Sialidae) is entirely extinct. Country-level geographic distribution data are provided for all species and subspecies. Synoptic type data are provided for taxa in the family and genus groups. Summary data are given for the numbers of megalopteran species currently known to occur in each of the major biogeographical regions of the world, and for the world fauna. Increase of knowledge about the diversity of the world Megaloptera fauna is summarized in counts of valid species described per decade and in a global taxonomic description curve. An updated set of keys to the world families, subfamilies, and genera of the Megaloptera is also provided.
“Shades” of Postmortem Personal Identity: ψυχή καὶ εἴδωλον in the Dream Passage (Il. 23.103-104)
(2013)
In a recent contribution entitled, “Homer’s Challenge to Philosophical Psychology,” Fred Miller proposes an “aporetic approach” to the Homeric poems. That is to say, a close reading of the epics reveals “serious aporiai,” at least insofar as philosophical consistency is concerned. Homeric readers, ancient and modern alike, have found irreconcilably-different answers to our perennial questions about humanity and divinity, fate and free will. To his credit, Miller rightly relieves Homer of an undue burden – viz., that of addressing the philosophical problems of later generations. “The analysis of concepts and the resolution of aporiai”: these are, as Miller notes, definitively not the priorities of an epic bard. Instead, such poets, working freely within the parameters of their oral traditions, understandably use language in ways not strictly-philosophical. Ultimately, Miller wants to argue that the ambiguities of Homer’s poetic language hastened Greece’s philosophical awakening...
Research on collective resilience processes still lacks a detailed understanding of psychological mechanisms at work when groups cope with adverse conditions, i.e., long-term processes, and how such mechanisms affect physical and mental well-being. As collective resilience will play a crucial part in facing looming climate change-related events such as floods, it is important to investigate these processes further. To this end, this study takes a novel holistic approach by combining resilience research, social psychology, and an archeological perspective to investigate the role of social identity as a collective resilience factor in the past and present. We hypothesize that social identification buffers against the negative effects of environmental threats in participants, which increases somatic symptoms related to stress, in a North Sea region historically prone to floods. A cross-sectional study (N = 182) was conducted to analyze the moderating effects of social identification on the relations between perceived threat of North Sea floods and both well-being and life satisfaction. The results support our hypothesis that social identification attenuates the relationship between threat perception and well-being, such that the relation is weaker for more strongly identified individuals. Contrary to our expectations, we did not find this buffering effect to be present for life satisfaction. Future resilience studies should further explore social identity as a resilience factor and how it operates in reducing environmental stress put on individuals and groups. Further, to help communities living in flood-prone areas better cope with future environmental stress, we recommend implementing interventions strengthening their social identities and hence collective resilience.
In this contribution I shall be interested, among other things, in finding a place for the European phenomenon of the ›Speculum humanae salvationis‹ within German literary history, which will inescapably involve revisiting the unfashionable discussion of date and origins. I also intend to ask about the place of this text in the ‘didactic’ literature of the Middle Ages. Is a religious text structured according to sacred history didactic? Much didactic poetry is in the vernacular: What does it mean that the ›Speculum‹ was composed in Latin? And what place should be accorded to its vernacular reception? The ›Speculum‹ is inscribed within a set of oppositions that would appear to be recurrent in the didactic literature of the later Middle Ages: Latin and vernacular, verse and prose, words and pictures, religious and profane, moral
teaching and devotion, clerical and lay. In view of its exceptionally broad transmission in the German lands, both in Latin and in vernacular reworkings, is it possible to describe this text so that it takes a place within a larger picture? In some respects it may stand at a threshold in the history of European didacticism.
Retournement or turning of the aedeagus about its longitudinal axis through about 180o during development is known in Chrysomeloidea (Coleoptera). This change in the orientation of the organ may be observed during the postembryonic development. This change produces certain morphological effects. By observing these morphological features in the imago the retournement may be inferred. Such morphological features in Curculionidae (Coleoptera) are here recorded. From this it has been inferred not only that retournement of the aedeagus is included in the ontogeny of curculionids, but also that the change of orientation of the organ occurs by the same mechanism as in Chrysomeloidea. These inferences attest the notion of a close phyletic relationship between the superfamilies Curculionoidea and Chrysomeloidea.
ϕ-meson production in In–In collisions at Elab=158A GeV: Evidence for relics of a thermal phase
(2010)
Yields and transverse mass distributions of the ϕ-mesons reconstructed in the ϕ→μ+μ− channel in In+In collisions at Elab=158A GeV are calculated within an integrated Boltzmann+hydrodynamics hybrid approach based on the Ultrarelativistic Quantum Molecular Dynamics (UrQMD) transport model with an intermediate hydrodynamic stage. The analysis is performed for various centralities and a comparison with the corresponding NA60 data in the muon channel is presented. We find that the hybrid model, that embeds an intermediate locally equilibrated phase subsequently mapped into the transport dynamics according to thermal phase-space distributions, gives a good description of the experimental data, both in yield and slope. On the contrary, the pure transport model calculations tend to fail in catching the general properties of the ϕ meson production: not only the yield, but also the slope of the mT spectra, compare poorly with the experimental observations at top SPS energies.
The first study of ϕ-meson production in p–Pb collisions at forward and backward rapidity, at a nucleon–nucleon centre-of-mass energy √sNN=5.02 TeV, has been performed with the ALICE apparatus at the LHC. The ϕ-mesons have been identified in the dimuon decay channel in the transverse momentum (pT) range 1<pT<7 GeV/c, both in the p-going (2.03<y<3.53) and the Pb-going (−4.46<y<−2.96) directions — where y stands for the rapidity in the nucleon–nucleon centre-of-mass — the integrated luminosity amounting to 5.01±0.19 nb−1 and 5.81±0.20 nb−1, respectively, for the two data samples. Differential cross sections as a function of transverse momentum and rapidity are presented. The forward–backward ratio for ϕ-meson production is measured for 2.96<|y|<3.53, resulting in a ratio ∼0.5 with no significant pT dependence within the uncertainties. The pT dependence of the ϕ nuclear modification factor RpPb exhibits an enhancement up to a factor 1.6 at pT=3–4 GeV/c in the Pb-going direction. The pT dependence of the ϕ-meson cross section in pp collisions at √s=2.76 TeV, which is used to determine a reference for the p–Pb results, is also presented here for 1<pT<5 GeV/c and 2.5<y<4, for a 78±3 nb−1 integrated luminosity sample.
The current status of research related to the behavior of the ϕ meson in nuclear matter is reviewed. First, recent theoretical works based of QCD sum rules and effective theory approaches are discussed. Next, preliminary results of transport simulations of pA reactions, with the goal of reproducing the dilepton spectra of the KEK E325 experiment are presented.
ϕ meson measurements provide insight into strangeness production, which is one of the key observables for the hot medium formed in high-energy heavy-ion collisions. ALICE measured ϕ production through its decay in muon pairs in Pb–Pb collisions at sNN−−−√=2.76 TeV in the intermediate transverse momentum range 2<pT<5 GeV/c and in the rapidity interval 2.5<y<4. The ϕ yield was measured as a function of the transverse momentum and collision centrality. The nuclear modification factor was obtained as a function of the average number of participating nucleons. Results were compared with the ones obtained via the kaon decay channel in the same pT range at midrapidity. The values of the nuclear modification factor in the two rapidity regions are in agreement within uncertainties.
Inclusive ϒ(1S) and ϒ(2S) production have been measured in Pb–Pb collisions at the centre-of-mass energy per nucleon–nucleon pair √sNN = 5.02 TeV, using the ALICE detector at the CERN LHC. The ϒ mesons are reconstructed in the centre-of-mass rapidity interval 2.5 < y < 4 and in the transversemomentum range pT < 15 GeV/c, via their decays to muon pairs. In this Letter, we present results on the inclusive ϒ(1S) nuclear modification factor RAA as a function of collision centrality, transverse momentum and rapidity. The ϒ(1S) and ϒ(2S) RAA, integrated over the centrality range 0–90%, are 0.37± 0.02(stat) ± 0.03(syst) and 0.10 ± 0.04(stat) ± 0.02(syst), respectively, leading to a ratio Rϒ(2S) AA /Rϒ(1S) AA of 0.28±0.12(stat)±0.06(syst). The observed ϒ(1S) suppression increases with the centrality of the collision and no significant variation is observed as a function of transverse momentum and rapidity.
Inclusive Υ(1S) and Υ(2S) production have been measured in Pb-Pb collisions at the centre-of-mass energy per nucleon-nucleon pair sNN−−−√=5.02 TeV, using the ALICE detector at the CERN LHC. The Υ mesons are reconstructed in the centre-of-mass rapidity interval 2.5<y<4 and in the transverse-momentum range pT<15 GeV/c, via their decays to muon pairs. In this Letter, we present results on the inclusive Υ(1S) nuclear modification factor RAA as a function of collision centrality, transverse momentum and rapidity. The Υ(1S) and Υ(2S) RAA, integrated over the centrality range 0-90%, are 0.37±0.02(stat)±0.03(syst) and 0.10±0.04(stat)±0.02(syst), respectively, leading to a ratio RΥ(2S)AA/RΥ(1S)AA of 0.28±0.12(stat)±0.06(syst). The observed Υ(1S) suppression increases with the centrality of the collision and no significant variation is observed as a function of transverse momentum and rapidity.
Inclusive Υ(1S) and Υ(2S) production have been measured in Pb-Pb collisions at the centre-of-mass energy per nucleon-nucleon pair sNN−−−√=5.02 TeV, using the ALICE detector at the CERN LHC. The Υ mesons are reconstructed in the centre-of-mass rapidity interval 2.5<y<4 and in the transverse-momentum range pT<15 GeV/c, via their decays to muon pairs. In this Letter, we present results on the inclusive Υ(1S) nuclear modification factor RAA as a function of collision centrality, transverse momentum and rapidity. The Υ(1S) and Υ(2S) RAA, integrated over the centrality range 0-90%, are 0.37±0.02(stat)±0.03(syst) and 0.10±0.04(stat)±0.02(syst), respectively, leading to a ratio RΥ(2S)AA/RΥ(1S)AA of 0.28±0.12(stat)±0.06(syst). The observed Υ(1S) suppression increases with the centrality of the collision and no significant variation is observed as a function of transverse momentum and rapidity.
ϒ production in p–Pb interactions is studied at the centre-of-mass energy per nucleon–nucleon collision √sNN = 8.16 TeV with the ALICE detector at the CERN LHC. The measurement is performed reconstructing bottomonium resonances via their dimuon decay channel, in the centre-of-mass rapidity intervals 2.03 < ycms < 3.53 and −4.46 < ycms < −2.96, down to zero transverse momentum. In this work, results on the ϒ(1S) production cross section as a function of rapidity and transverse momentum are presented. The corresponding nuclear modification factor shows a suppression of the ϒ(1S) yields with respect to pp collisions, both at forward and backward rapidity. This suppression is stronger in the low transverse momentum region and shows no significant dependence on the centrality of the interactions. Furthermore, the ϒ(2S) nuclear modification factor is evaluated, suggesting a suppression similar to that of the ϒ(1S). A first measurement of the ϒ(3S) has also been performed. Finally, results are compared with previous ALICE measurements in p–Pb collisions at √sNN = 5.02 TeV and with theoretical calculations.
Υ production in p-Pb interactions is studied at the centre-of-mass energy per nucleon-nucleon collision sNN−−−√ = 8.16 TeV with the ALICE detector at the CERN LHC. The measurement is performed reconstructing bottomonium resonances via their dimuon decay channel, in the centre-of-mass rapidity intervals 2.03<ycms<3.53 and −4.46<ycms<−2.96, down to zero transverse momentum. In this work, results on the inclusive Υ(1S) production cross section as a function of rapidity and transverse momentum are presented. The corresponding nuclear modification factor shows a suppression of the Υ(1S) yields with respect to pp collisions, both at forward and backward rapidity. This suppression is stronger in the low transverse momentum region and shows no significant dependence on the centrality of the interactions. Furthermore, the Υ(2S) nuclear modification factor is also evaluated, suggesting a suppression similar to that of the Υ(1S). A first measurement of the Υ(3S) has also been performed. Finally, results are compared with previous measurements performed by ALICE in p-Pb collisions at sNN−−−√ = 5.02 TeV and with theoretical calculations.
Υ production in p-Pb interactions is studied at the centre-of-mass energy per nucleon-nucleon collision sNN−−−√ = 8.16 TeV with the ALICE detector at the CERN LHC. The measurement is performed reconstructing bottomonium resonances via their dimuon decay channel, in the centre-of-mass rapidity intervals 2.03<ycms<3.53 and −4.46<ycms<−2.96, down to zero transverse momentum. In this work, results on the inclusive Υ(1S) production cross section as a function of rapidity and transverse momentum are presented. The corresponding nuclear modification factor shows a suppression of the Υ(1S) yields with respect to pp collisions, both at forward and backward rapidity. This suppression is stronger in the low transverse momentum region and shows no significant dependence on the centrality of the interactions. Furthermore, the Υ(2S) nuclear modification factor is also evaluated, suggesting a suppression similar to that of the Υ(1S). A first measurement of the Υ(3S) has also been performed. Finally, results are compared with previous measurements performed by ALICE in p-Pb collisions at sNN−−−√ = 5.02 TeV and with theoretical calculations.
ϒ production and nuclear modification at forward rapidity in Pb–Pb collisions at √sNN = 5.02TeV
(2021)
The production of ϒ mesons in Pb–Pb collisions at a centre-of-mass energy per nucleon pair √sNN = 5.02 TeV is measured with the muon spectrometer of the ALICE detector at the LHC. The yields as well as the nuclear modification factors are determined in the forward rapidity region 2.5 < y < 4.0, as a function of rapidity, transverse momentum and collision centrality. The results show that the production of the ϒ(1S) meson is suppressed by a factor of about three with respect to the production in proton–proton collisions. For the first time, a significant signal for the ϒ(2S) meson is observed at forward rapidity, indicating a suppression stronger by about a factor 2–3 with respect to the ground state. The measurements are compared with transport, hydrodynamic, comover and statistical hadronisation model calculations.
ϒ production and nuclear modification at forward rapidity in Pb–Pb collisions at √sNN = 5.02 TeV
(2021)
The production of Υ mesons in Pb-Pb collisions at a centre-of-mass energy per nucleon pair sNN−−−√ = 5 TeV is measured with the muon spectrometer of the ALICE detector at the LHC. The yields as well as the nuclear modification factors are determined in the forward rapidity region 2.5<y<4.0, as a function of rapidity, transverse momentum and collision centrality. The results show that the production of the Υ(1S) meson is suppressed by a factor of about three with respect to the production in proton-proton collisions. For the first time, a significant signal for the Υ(2S) meson is observed at forward rapidity, indicating a suppression stronger by about a factor 2-3 with respect to the ground state. The measurements are compared with transport, hydrodynamic, comover and statistical hadronisation model calculations.
ϒ production and nuclear modification at forward rapidity in Pb–Pb collisions at √sNN = 5.02 TeV
(2020)
The production of Υ mesons in Pb-Pb collisions at a centre-of-mass energy per nucleon pair sNN−−−√ = 5 TeV is measured with the muon spectrometer of ALICE at the LHC. The yields as well as the nuclear modification factors are determined in the forward rapidity region 2.5<y<4.0, as a function of rapidity, transverse momentum and collision centrality. The results show that the production of Υ(1S) is suppressed by a factor of about three with respect to the production in proton-proton collisions. For the first time, a significant Υ(2S) signal is observed at forward rapidity, indicating a suppression stronger by about a factor 2-3 with respect to the ground state. The measurements are compared with transport, hydrodynamic, comover and statistical hadronisation model calculations.
Results are presented on Omega production in central Pb+Pb collisions at 40 and 158 AGeV beam energy. Given are transverse-mass spectra, rapidity distributions, and total yields for the sum Omega+Antiomega at 40 AGeV and for Omega and Antiomega separately at 158 AGeV. The yields are strongly under-predicted by the string-hadronic UrQMD model and are in better agreement with predictions from a hadron gas models. PACS numbers: 25.75.Dw
ω-Azido fatty acids as probes to detect fatty acid biosynthesis, degradation, and modification
(2014)
FAs play a central role in the metabolism of almost all known cellular life forms. Although GC-MS is regarded as a standard method for FA analysis, other methods, such as HPLC/MS, are nowadays widespread but are rarely applied to FA analysis. Here we present azido-FAs as probes that can be used to study FA biosynthesis (elongation, desaturation) or degradation (β-oxidation) upon their uptake, activation, and metabolic conversion. These azido-FAs are readily accessible by chemical synthesis and their matization with high sensitivity by HPLC/MS, contributing a powerful tool to FA analysis, and hence, lipid analysis in general.
The transverse mass spectra of J/psi and psi' mesons and Omega hyperons produced in central Au+Au collisions at RHIC energies are discussed within a statistical model used successfully for the interpretation of the SPS results. The comparison of the presented model with the future RHIC data should serve as a further crucial test of the hypothesis of statistical production of charmonia at hadronization. Finally, in case of validity, the approach should allow to estimate the mean transverse flow velocity at the quark gluon plasma hadronization.
The transverse mass spectra of J/ψ and ψ′ mesons and Ω hyperons produced in central Au+Au collisions at RHIC energies are discussed within a statistical model used successfully for the interpretation of the SPS results. The comparison of the presented model with the future RHIC data should serve as a further crucial test of the hypothesis of statistical production of charmonia at hadronization. Finally, in case of validity, the approach should allow to estimate the mean transverse flow velocity at the quark–gluon plasma hadronization.
The transverse mass spectra of Omega, J/psi and psi' in Pb+Pb collisions at 158 AGeV are studied within a hydrodynamical model of the quark gluon plasma expansion and hadronization. The model reproduces the existing data with the common hadronization parameters: temperature T=T_H = 170 MeV and average collective transverse velocity v_T = 0.2.
The first measurement of ϕ-meson production in p-Pb collisions at a nucleon-nucleon centre-of-mass energy sNN−−−√ = 5.02 TeV has been performed with the ALICE apparatus at the LHC. The ϕ-mesons have been identified in the dimuon decay channel in the transverse momentum (pT) range 1<pT<7 GeV/c, both in the p-going (2.03<y<3.53) and the Pb-going (−4.46<y<−2.96) directions, where y stands for the rapidity in the nucleon-nucleon centre-of-mass. Differential cross sections as a function of transverse momentum and rapidity are presented. The forward-backward asymmetry for ϕ-meson production is measured for 2.96<|y|<3.53, resulting in a factor ∼0.5 with no significant pT dependence within the uncertainties. The pT dependence of the ϕ nuclear modification factor RpPb exhibits an enhancement up to a factor 1.6 at pT = 3-4 GeV/c in the Pb-going direction. The pT dependence of the ϕ-meson cross section in pp collisions at s√ = 2.76 TeV, which is used to determine a reference for the p-Pb results, is also presented here for 1<pT<5 GeV/c and 2.5<y<4.
The first study of ϕ-meson production in p-Pb collisions at forward and backward rapidity, at a nucleon-nucleon centre-of-mass energy sNN−−−√=5.02~TeV, has been performed with the ALICE apparatus at the LHC. The ϕ-mesons have been identified in the dimuon decay channel in the transverse momentum (pT) range 1<pT<7 GeV/c, both in the p-going (2.03<y<3.53) and the Pb-going (−4.46<y<−2.96) directions, where y stands for the rapidity in the nucleon-nucleon centre-of-mass, the integrated luminosity amounting to 5.01±0.19~nb−1 and 5.81±0.20~nb−1, respectively, for the two data samples. Differential cross sections as a function of transverse momentum and rapidity are presented. The forward-backward ratio for ϕ-meson production is measured for 2.96<|y|<3.53, resulting in a ratio ∼0.5 with no significant pT dependence within the uncertainties. The pT dependence of the ϕ nuclear modification factor RpPb exhibits an enhancement up to a factor 1.6 at pT = 3-4 GeV/c in the Pb-going direction. The pT dependence of the ϕ-meson cross section in pp collisions at s√ = 2.76 TeV, which is used to determine a reference for the p-Pb results, is also presented here for 1<pT<5 GeV/c and 2.5<y<4 for a 78±3~nb−1 integrated luminosity sample.
The first study of ϕ-meson production in p-Pb collisions at forward and backward rapidity, at a nucleon-nucleon centre-of-mass energy sNN−−−√=5.02~TeV, has been performed with the ALICE apparatus at the LHC. The ϕ-mesons have been identified in the dimuon decay channel in the transverse momentum (pT) range 1<pT<7 GeV/c, both in the p-going (2.03<y<3.53) and the Pb-going (−4.46<y<−2.96) directions, where y stands for the rapidity in the nucleon-nucleon centre-of-mass, the integrated luminosity amounting to 5.01±0.19~nb−1 and 5.81±0.20~nb−1, respectively, for the two data samples. Differential cross sections as a function of transverse momentum and rapidity are presented. The forward-backward ratio for ϕ-meson production is measured for 2.96<|y|<3.53, resulting in a ratio ∼0.5 with no significant pT dependence within the uncertainties. The pT dependence of the ϕ nuclear modification factor RpPb exhibits an enhancement up to a factor 1.6 at pT = 3-4 GeV/c in the Pb-going direction. The pT dependence of the ϕ-meson cross section in pp collisions at s√ = 2.76 TeV, which is used to determine a reference for the p-Pb results, is also presented here for 1<pT<5 GeV/c and 2.5<y<4 for a 78±3~nb−1 integrated luminosity sample.
ϕ meson measurements provide insight into strangeness production, which is one of the key observables for the hot medium formed in high-energy heavy-ion collisions. ALICE measured ϕ production through its decay in muon pairs in Pb-Pb collisions at sNN−−−√ = 2.76 TeV in the intermediate transverse momentum range 2<pT<5 GeV/c and in the rapidity interval 2.5<y<4. The ϕ yield was measured as a function of the transverse momentum and collision centrality. The nuclear modification factor was obtained as a function of the average number of participating nucleons. Results were compared with the ones obtained via the kaon decay channel in the same pT range at midrapidity. The values of the nuclear modification factor in the two rapidity regions are in agreement within uncertainties.
ϕ meson measurements provide insight into strangeness production, which is one of the key observables for the hot medium formed in high-energy heavy-ion collisions. ALICE measured ϕ production through its decay in muon pairs in Pb-Pb collisions at sNN−−−√ = 2.76 TeV in the intermediate transverse momentum range 2<pT<5 GeV/c and in the rapidity interval 2.5<y<4. The ϕ yield was measured as a function of the transverse momentum and collision centrality. The nuclear modification factor was obtained as a function of the average number of participating nucleons. Results were compared with the ones obtained via the kaon decay channel in the same pT range at midrapidity. The values of the nuclear modification factor in the two rapidity regions are in agreement within uncertainties.
The production of Σ0 baryons in the nuclear reaction p (3.5 GeV) + Nb (corresponding to sNN=3.18 GeV) is studied with the detector set-up HADES at GSI, Darmstadt. Σ0s were identified via the decay Σ0→Λγ with subsequent decays Λ→pπ− in coincidence with a e+e− pair from either external (γ→e+e−) or internal (Dalitz decay γ⁎→e+e−) gamma conversions. The differential Σ0 cross section integrated over the detector acceptance, i.e. the rapidity interval 0.5<y<1.1, has been extracted as ΔσΣ0=2.3±(0.2)stat±(−0.6+0.6)sys±(0.2)norm mb, yielding the inclusive production cross section in full phase space σΣ0total=5.8±(0.5)stat±(−1.4+1.4)sys±(0.6)norm±(1.7)extrapol mb by averaging over different extrapolation methods. The Λall/Σ0 ratio within the HADES acceptance is equal to 2.3±(0.2)stat±(−0.6+0.6)sys. The obtained rapidity and momentum distributions are compared to transport model calculations. The Σ0 yield agrees with the statistical model of particle production in nuclear reactions. Keywords: Hyperons, Strangeness, Proton, Nucleus.
Hadronic resonances are used to probe the hadron gas produced in the late stage of heavy-ion collisions since they decay on the same timescale, of the order of 1 to 10 fm/c, as the decoupling time of the system. In the hadron gas, (pseudo)elastic scatterings among the products of resonances that decayed before the kinetic freeze-out and regeneration processes counteract each other, the net effect depending on the resonance lifetime, the duration of the hadronic phase, and the hadronic cross sections at play. In this context, the Σ(1385)± particle is of particular interest as models predict that regeneration dominates over rescattering despite its relatively short lifetime of about 5.5 fm/c. The first measurement of the Σ(1385)± resonance production at midrapidity in Pb-Pb collisions at sNN−−−√=5.02 TeV with the ALICE detector is presented in this Letter. The resonances are reconstructed via their hadronic decay channel, Λπ, as a function of the transverse momentum (pT) and the collision centrality. The results are discussed in comparison with the measured yield of pions and with expectations from the statistical hadronization model as well as commonly employed event generators, including PYTHIA8/Angantyr and EPOS3 coupled to the UrQMD hadronic cascade afterburner. None of the models can describe the data. For Σ(1385)±, a similar behaviour as K∗(892)0 is observed in data unlike the predictions of EPOS3 with afterburner.
Hadronic resonances are used to probe the hadron gas produced in the late stage of heavy-ion collisions since they decay on the same timescale, of the order of 1 to 10 fm/c, as the decoupling time of the system. In the hadron gas, (pseudo)elastic scatterings among the products of resonances that decayed before the kinetic freeze-out and regeneration processes counteract each other, the net effect depending on the resonance lifetime, the duration of the hadronic phase, and the hadronic cross sections at play. In this context, the Σ(1385)± particle is of particular interest as models predict that regeneration dominates over rescattering despite its relatively short lifetime of about 5.5 fm/c. The first measurement of the Σ(1385)± resonance production at midrapidity in Pb-Pb collisions at sNN−−−√=5.02 TeV with the ALICE detector is presented in this Letter. The resonances are reconstructed via their hadronic decay channel, Λπ, as a function of the transverse momentum (pT) and the collision centrality. The results are discussed in comparison with the measured yield of pions and with expectations from the statistical hadronization model as well as commonly employed event generators, including PYTHIA8/Angantyr and EPOS3 coupled to the UrQMD hadronic cascade afterburner. None of the models can describe the data. For Σ(1385)±, a similar behaviour as K∗(892)0 is observed in data unlike the predictions of EPOS3 with afterburner.
Hadronic resonances are used to probe the hadron gas produced in the late stage of heavy-ion collisions since they decay on the same timescale, of the order of 1 to 10 fm/c, as the decoupling time of the system. In the hadron gas, (pseudo)elastic scatterings among the products of resonances that decayed before the kinetic freeze-out and regeneration processes counteract each other, the net effect depending on the resonance lifetime, the duration of the hadronic phase, and the hadronic cross sections at play. In this context, the Σ(1385)± particle is of particular interest as models predict that regeneration dominates over rescattering despite its relatively short lifetime of about 5.5 fm/c. The first measurement of the Σ(1385)± resonance production at midrapidity in Pb-Pb collisions at sNN−−−√=5.02 TeV with the ALICE detector is presented in this Letter. The resonances are reconstructed via their hadronic decay channel, Λπ, as a function of the transverse momentum (pT) and the collision centrality. The results are discussed in comparison with the measured yield of pions and with expectations from the statistical hadronization model as well as commonly employed event generators, including PYTHIA8/Angantyr and EPOS3 coupled to the UrQMD hadronic cascade afterburner. None of the models can describe the data. For Σ(1385)±, a similar behaviour as K∗(892)0 is observed in data unlike the predictions of EPOS3 with afterburner.
An invariant differential cross section measurement of inclusive π0 and η meson production at mid-rapidity in pp collisions at s√=8 TeV was carried out by the ALICE experiment at the LHC. The spectra of π0 and η mesons were measured in transverse momentum ranges of 0.3<p T <35 GeV/c and 0.5<p T <35 GeV/c , respectively. Next-to-leading order perturbative QCD calculations using fragmentation functions DSS14 for the π0 and AESSS for the η overestimate the cross sections of both neutral mesons, although such calculations agree with the measured η/π0 ratio within uncertainties. The results were also compared with PYTHIA 8.2 predictions for which the Monash 2013 tune yields the best agreement with the measured neutral meson spectra. The measurements confirm a universal behavior of the η/π0 ratio seen for NA27, PHENIX and ALICE data for pp collisions from s√=27.5 GeV to s√=8 TeV within experimental uncertainties. A relation between the π0 and η production cross sections for pp collisions at s√=8 TeV is given by m T scaling for p T >3.5 GeV/c . However, a deviation from this empirical scaling rule is observed for transverse momenta below p T <3.5 GeV/c in the η/π0 ratio with a significance of 6.2σ.
An invariant differential cross section measurement of inclusive π0 and η meson production at mid-rapidity in pp collisions at s√=8 TeV was carried out by the ALICE experiment at the LHC. The spectra of neutral mesons π0 and η were measured in transverse momentum ranges of 0.3<pT<35 GeV/c and 0.5<pT<35 GeV/c, respectively. Next-to-leading order perturbative QCD calculations using fragmentation functions DSS14 for π0 and AESSS for η overestimate the cross sections of both neutral mesons, but agree with the measured η/π0 ratio within uncertainties. The results are also compared with PYTHIA~8.2 predictions for which the Monash~2013 tune yields the best agreement with the measured neutral meson spectra. The measurements confirm a universal behavior of the η/π0 ratio seen for NA27, PHENIX and ALICE data for pp collisions from s√=27.5 GeV to s√=8 TeV within experimental uncertainties. A relation between the π0 and η production cross sections for pp collisions at s√=8 TeV is given by mT scaling for pT>3.5 GeV/c. However, a deviation from this empirical scaling law is observed for transverse momenta below pT<3.5 GeV/c in the η/π0 ratio with a significance of 6.2σ.
An invariant differential cross section measurement of inclusive π0 and η meson production at mid-rapidity in pp collisions at s√=8 TeV was carried out by the ALICE experiment at the LHC. The spectra of π0 and η mesons were measured in transverse momentum ranges of 0.3<pT<35 GeV/c and 0.5<pT<35 GeV/c, respectively. Next-to-leading order perturbative QCD calculations using fragmentation functions DSS14 for the π0 and AESSS for the η overestimate the cross sections of both neutral mesons, although such calculations agree with the measured η/π0 ratio within uncertainties. The results were also compared with PYTHIA~8.2 predictions for which the Monash~2013 tune yields the best agreement with the measured neutral meson spectra. The measurements confirm a universal behavior of the η/π0 ratio seen for NA27, PHENIX and ALICE data for pp collisions from s√=27.5 GeV to s√=8 TeV within experimental uncertainties. A relation between the π0 and η production cross sections for pp collisions at s√=8 TeV is given by mT scaling for pT>3.5 GeV/c. However, a deviation from this empirical scaling rule is observed for transverse momenta below pT<3.5 GeV/c in the η/π0 ratio with a significance of 6.2σ.
We study odd parity J=1/2 and J=3/2 Ξc resonances using a unitarized coupled-channel framework based on a SU(6)lsf×HQSS-extended Weinberg–Tomozawa baryon–meson interaction, while paying a special attention to the renormalization procedure. We predict a large molecular ΛcK¯ component for the Ξc(2790) with a dominant 0− light-degree-of-freedom spin configuration. We discuss the differences between the 3/2− Λc(2625) and Ξc(2815) states, and conclude that they cannot be SU(3) siblings, whereas we predict the existence of other Ξc-states, one of them related to the two-pole structure of the Λc(2595). It is of particular interest a pair of J=1/2 and J=3/2 poles, which form a HQSS doublet and that we tentatively assign to the Ξc(2930) and Ξc(2970), respectively. Within this picture, the Ξc(2930) would be part of a SU(3) sextet, containing either the Ωc(3090) or the Ωc(3119), and that would be completed by the Σc(2800). Moreover, we identify a J=1/2 sextet with the Ξb(6227) state and the recently discovered Σb(6097). Assuming the equal spacing rule and to complete this multiplet, we predict the existence of a J=1/2 Ωb odd parity state, with a mass of 6360 MeV and that should be seen in the ΞbK¯ channel.
Using the NA49 main TPC, the central production of hyperons has been measured in CERN SPS Pb - Pb collisions at 158 GeV c-1. The preliminary ratio, studied at 2.0 < y < 2.6 and 1 < pT < 3 GeV c-1, equals ~ (13 ± 4)% (systematic error only). It is compatible, within errors, with the previously obtained ratios for central S + S [1], S + W [2], and S + Au [3] collisions. The fit to the transverse momentum distribution resulted in an inverse slope parameter T of 297 MeV. At this level of statistics we do not see any noticeable enhancement of hyperon production with the increased volume (and, possibly, degree of equilibration) of the system from S + S to Pb + Pb. This result is unexpected and counterintuitive, and should be further investigated. If confirmed, it will have a significant impact on our understanding of mechanisms leading to the enhanced strangeness production in heavy-ion collisions.
Ongoing brain activity has been implicated in the modulation of cortical excitability. The combination of electroencephalography (EEG) and transcranial magnetic stimulation (TMS) in a real-time triggered setup is a novel method for testing hypotheses about the relationship between spontaneous neuronal oscillations, cortical excitability, and synaptic plasticity. For this method, a reliable real-time extraction of the neuronal signal of interest from scalp EEG with high signal-to-noise ratio (SNR) is of crucial importance. Here we compare individually tailored spatial filters as computed by spatial-spectral decomposition (SSD), which maximizes SNR in a frequency band of interest, against established local C3-centered Laplacian filters for the extraction of the sensorimotor μ-rhythm. Single-pulse TMS over the left primary motor cortex was synchronized with the surface positive or negative peak of the respective extracted signal, and motor evoked potentials (MEP) were recorded with electromyography (EMG) of a contralateral hand muscle. Both extraction methods led to a comparable degree of MEP amplitude modulation by phase of the sensorimotor μ-rhythm at the time of stimulation. This could be relevant for targeting other brain regions with no working benchmark such as the local C3-centered Laplacian filter, as sufficient SNR is an important prerequisite for reliable real-time single-trial detection of EEG features.
The first measurements of the scattering parameters of ΛK pairs in all three charge combinations (ΛK+, ΛK−, and ΛK0S) are presented. The results are achieved through a femtoscopic analysis of ΛK correlations in Pb-Pb collisions at sNN−−−√ = 2.76 TeV recorded by ALICE at the LHC. The femtoscopic correlations result from strong final-state interactions, and are fit with a parametrization allowing for both the characterization of the pair emission source and the measurement of the scattering parameters for the particle pairs. Extensive studies with the THERMINATOR 2 event generator provide a good description of the non-femtoscopic background, which results mainly from collective effects, with unprecedented precision. Furthermore, together with HIJING simulations, this model is used to account for contributions from residual correlations induced by feed-down from particle decays. The extracted scattering parameters indicate that the strong force is repulsive in the ΛK+ interaction and attractive in the ΛK− interaction. The data hint that the and ΛK0S interaction is attractive, however the uncertainty of the result does not permit such a decisive conclusion. The results suggest an effect arising either from different quark-antiquark interactions between the pairs (ss¯ in ΛK+ and uu¯¯¯ in ΛK−) or from different net strangeness for each system (S = 0 for ΛK+, and S = −2 for ΛK−). Finally, the ΛK systems exhibit source radii larger than expected from extrapolation from identical particle femtoscopic studies. This effect is interpreted as resulting from the separation in space-time of the single-particle Λ and K source distributions.
The first measurements of the scattering parameters of ΛK pairs in all three charge combinations (ΛK+, ΛK−, and ΛK0S) are presented. The results are achieved through a femtoscopic analysis of ΛK correlations in Pb-Pb collisions at sNN−−−√ = 2.76 TeV recorded by ALICE at the LHC. The femtoscopic correlations result from strong final-state interactions, and are fit with a parametrization allowing for both the characterization of the pair emission source and the measurement of the scattering parameters for the particle pairs. Extensive studies with the THERMINATOR 2 event generator provide a good description of the non-femtoscopic background, which results mainly from collective effects, with unprecedented precision. Furthermore, together with HIJING simulations, this model is used to account for contributions from residual correlations induced by feed-down from particle decays. The extracted scattering parameters indicate that the strong force is repulsive in the ΛK+ interaction and attractive in the ΛK− interaction. The data hint that the and ΛK0S interaction is attractive, however the uncertainty of the result does not permit such a decisive conclusion. The results suggest an effect arising either from different quark-antiquark interactions between the pairs (ss¯ in ΛK+ and uu¯¯¯ in ΛK−) or from different net strangeness for each system (S = 0 for ΛK+, and S = −2 for ΛK−). Finally, the ΛK systems exhibit source radii larger than expected from extrapolation from identical particle femtoscopic studies. This effect is interpreted as resulting from the separation in space-time of the single-particle Λ and K source distributions.
The first measurements of the scattering parameters of ΛK pairs in all three charge combinations (ΛK+, ΛK−, and ΛK0S) are presented. The results are achieved through a femtoscopic analysis of ΛK correlations in Pb-Pb collisions at sNN−−−√ = 2.76 TeV recorded by ALICE at the LHC. The femtoscopic correlations result from strong final-state interactions, and are fit with a parametrization allowing for both the characterization of the pair emission source and the measurement of the scattering parameters for the particle pairs. Extensive studies with the THERMINATOR 2 event generator provide a good description of the non-femtoscopic background, which results mainly from collective effects, with unprecedented precision. Furthermore, together with HIJING simulations, this model is used to account for contributions from residual correlations induced by feed-down from particle decays. The extracted scattering parameters indicate that the strong force is repulsive in the ΛK+ interaction and attractive in the ΛK− and ΛK0S interactions. The results suggest an effect arising either from different quark-antiquark interactions between the pairs (ss¯ in ΛK+ and uu¯¯¯ in ΛK−) or from different net strangeness for each system (S = 0 for ΛK+, and S = −2 for ΛK−). Finally, the ΛK systems exhibit source radii larger than expected from extrapolation from identical particle femtoscopic studies. This effect is interpreted as resulting from the separation in space-time of the single-particle Λ and K source distributions.
The pT-differential production cross section of prompt Λ+c charmed baryons was measured with the ALICE detector at the Large Hadron Collider (LHC) in pp collisions at s√=7 TeV and in p-Pb collisions at sNN−−−√=5.02 TeV at midrapidity. The Λ+c and Λ¯¯¯¯−c were reconstructed in the hadronic decay modes Λ+c→pK−π+, Λ+c→pK0S and in the semileptonic channel Λ+c→e+νeΛ (and charge conjugates). The measured values of the Λ+c/D0 ratio, which is sensitive to the c-quark hadronisation mechanism, and in particular to the production of baryons, are presented and are larger than those measured previously in different colliding systems, centre-of-mass energies, rapidity and pT intervals, where the Λ+c production process may differ. The results are compared with the expectations obtained from perturbative Quantum Chromodynamics calculations and Monte Carlo event generators. Neither perturbative QCD calculations nor Monte Carlo models reproduce the data, indicating that the fragmentation of heavy-flavour baryons is not well understood. The first measurement at the LHC of the Λ+c nuclear modification factor, RpPb, is also presented. The RpPb is found to be consistent with unity and with that of D mesons within the uncertainties, and consistent with a theoretical calculation that includes cold nuclear matter effects and a calculation that includes charm quark interactions with a deconfined medium.
The pT-differential production cross section of prompt Λ+c charmed baryons was measured with the ALICE detector at the Large Hadron Collider (LHC) in pp collisions at s√=7 TeV and in p-Pb collisions at sNN−−−√=5.02 TeV at midrapidity. The Λ+c and Λ¯¯¯¯−c were reconstructed in the hadronic decay modes Λ+c→pK−π+, Λ+c→pK0S and in the semileptonic channel Λ+c→e+νeΛ (and charge conjugates). The measured values of the Λ+c/D0 ratio, which is sensitive to the c-quark hadronisation mechanism, and in particular to the production of baryons, are presented and are larger than those measured previously in different colliding systems, centre-of-mass energies, rapidity and pT intervals, where the Λ+c production process may differ. The results are compared with the expectations obtained from perturbative Quantum Chromodynamics calculations and Monte Carlo event generators. Neither perturbative QCD calculations nor Monte Carlo models reproduce the data, indicating that the fragmentation of heavy-flavour baryons is not well understood. The first measurement at the LHC of the Λ+c nuclear modification factor, RpPb, is also presented. The RpPb is found to be consistent with unity and with that of D mesons within the uncertainties, and consistent with a theoretical calculation that includes cold nuclear matter effects and a calculation that includes charm quark interactions with a deconfined medium.
The pT-differential production cross section of prompt Λ +c charmed baryons was measured with the ALICE detector at the Large Hadron Collider (LHC) in pp collisions at s√=7 TeV and in p-Pb collisions at sNN−−−√=5.02 TeV at midrapidity. The Λ +c and Λ¯¯¯¯c¯¯¯ were reconstructed in the hadronic decay modes Λ +c → pK−π+, Λ +c → pK 0S and in the semileptonic channel Λ +c → e+νeΛ (and charge conjugates). The measured values of the Λ +c/D0 ratio, which is sensitive to the c-quark hadronisation mechanism, and in particular to the production of baryons, are presented and are larger than those measured previously in different colliding systems, centre-of-mass energies, rapidity and pT intervals, where the Λ +c production process may differ. The results are compared with the expectations obtained from perturbative Quantum Chromodynamics calculations and Monte Carlo event generators. Neither perturbative QCD calculations nor Monte Carlo models reproduce the data, indicating that the fragmentation of heavy-flavour baryons is not well understood. The first measurement at the LHC of the Λ +c nuclear modification factor, RpPb, is also presented. The RpPb is found to be consistent with unity and with that of D mesons within the uncertainties, and consistent with a theoretical calculation that includes cold nuclear matter effects and a calculation that includes charm quark interactions with a deconfined medium.
The production cross section of prompt Λ+c charmed baryons was measured with the ALICE detector at the LHC at midrapidity in proton-proton (pp) and proton-lead (p-Pb) collisions at a centre-of-mass energy per nucleon pair of sNN−−−√=5.02 TeV. The Λ+c and Λ¯¯¯¯−c baryons were reconstructed in the hadronic decay channels Λ+c→pK−π+ and Λ+c→pK0S and respective charge conjugates. The measured differential cross sections as a function of transverse momentum (pT) and the pT-integrated Λ+c production cross section in pp and in p-Pb collisions are presented. The Λ+c nuclear modification factor (RpPb), calculated from the cross sections in pp and in p-Pb collisions, is presented and compared with the RpPb of D mesons. The Λ+c/D0 ratio is also presented and compared with the light-flavour baryon-to-meson ratios p/π and Λ/K0S, and measurements from other LHC experiments. The results are compared to predictions from model calculations and Monte Carlo event generators.
The production cross section of prompt Λ+c charm baryons was measured with the ALICE detector at the LHC at midrapidity in proton-proton (pp) and proton-lead (p-Pb) collisions at a centre-of-mass energy per nucleon pair of sNN−−−√=5.02 TeV. The Λ+c and Λ¯¯¯¯−c baryons were reconstructed in the hadronic decay channels Λ+c→pK−π+ and Λ+c→pK0S and respective charge conjugates. The measured differential cross sections as a function of transverse momentum (pT) and the pT-integrated Λ+c production cross section in pp and in p-Pb collisions are presented. The Λ+c nuclear modification factor (RpPb), calculated from the cross sections in pp and in p-Pb collisions, is presented and compared with the RpPb of D mesons. The Λ+c/D0 ratio is also presented and compared with the light-flavour baryon-to-meson ratios p/π and Λ/K0S, and measurements from other LHC experiments. The results are compared to predictions from model calculations and Monte Carlo event generators.
The production cross section of prompt Λ+c charm baryons was measured with the ALICE detector at the LHC at midrapidity in proton-proton (pp) and proton-lead (p-Pb) collisions at a centre-of-mass energy per nucleon pair of sNN−−−√=5.02 TeV. The Λ+c and Λ¯¯¯¯−c baryons were reconstructed in the hadronic decay channels Λ+c→pK−π+ and Λ+c→pK0S and respective charge conjugates. The measured differential cross sections as a function of transverse momentum (pT) and the pT-integrated Λ+c production cross section in pp and in p-Pb collisions are presented. The Λ+c nuclear modification factor (RpPb), calculated from the cross sections in pp and in p-Pb collisions, is presented and compared with the RpPb of D mesons. The Λ+c/D0 ratio is also presented and compared with the light-flavour baryon-to-meson ratios p/π and Λ/K0S, and measurements from other LHC experiments. The results are compared to predictions from model calculations and Monte Carlo event generators.
The production cross section of prompt Λ+c charmed baryons was measured with the ALICE detector at the LHC at midrapidity in proton-proton (pp) and proton-lead (p-Pb) collisions at a centre-of-mass energy per nucleon pair of sNN−−−√=5.02 TeV. The Λ+c and Λ¯¯¯¯−c baryons were reconstructed in the hadronic decay channels Λ+c→pK−π+ and Λ+c→pK0S and respective charge conjugates. The measured differential cross sections as a function of transverse momentum (pT) and the pT-integrated Λ+c production cross section in pp and in p-Pb collisions are presented. The Λ+c nuclear modification factor (RpPb), calculated from the cross sections in pp and in p-Pb collisions, is presented and compared with the RpPb of D mesons. The Λ+c/D0 ratio is also presented and compared with the light-flavour baryon-to-meson ratios p/π and Λ/K0S, and measurements from other LHC experiments. The results are compared to predictions from model calculations and Monte Carlo event generators.
A measurement of the production of prompt +c baryons in Pb–Pb collisions at √sNN = 5.02 TeV with the ALICE detector at the LHC is reported. The +c and − c were reconstructed at midrapidity (|y| < 0.5) via the hadronic decay channel +c → pK0 S (and charge conjugate) in the transverse momentum and centrality intervals 6 < pT < 12 GeV/c and 0–80%. The +c /D0 ratio, which is sensitive to the charm quark hadronisation mechanisms in the medium, is measured and found to be larger than the ratio measured in minimum-bias pp collisions at √s = 7 TeV and in p–Pb collisions at √sNN = 5.02 TeV. In particular, the values in p–Pb and Pb–Pb collisions differ by about two standard deviations of the combined statistical and systematic uncertainties in the common pT interval covered by the measurements in the two collision systems. The + c /D0 ratio is also compared with model calculations including different implementations of charm quark hadronisation. The measured ratio is reproduced by models implementing a pure coalescence scenario, while adding a fragmentation contribution leads to an underestimation. The + c nuclear modification factor, RAA, is also presented. The measured values of the RAA of + c , D+ s and non-strange D mesons are compatible within the combined statistical and systematic uncertainties. They show, however, a hint of a hierarchy (RD0 AA < RD+ s AA < R+ c AA ), conceivable with a contribution from coalescence mechanisms to charm hadron formation in the medium.
A measurement of the production of prompt Λ+c baryons in Pb-Pb collisions at sNN−−−√=5.02 TeV with the ALICE detector at the LHC is reported. The Λ+c and Λ¯¯¯¯−c were reconstructed at midrapidity (|y|<0.5) via the hadronic decay channel Λ+c→pK0S (and charge conjugate) in the transverse momentum and centrality intervals 6<pT<12 GeV/c and 0-80%. The Λ+c/D0 ratio, which is sensitive to the charm quark hadronisation mechanisms in the medium, is measured and found to be larger than the ratio measured in minimum-bias pp collisions at s√=7 TeV and in p-Pb collisions at sNN−−−√=5.02 TeV. In particular, the values in p-Pb and Pb-Pb collisions differ by about two standard deviations of the combined statistical and systematic uncertainties in the common pT interval covered by the measurements in the two collision system. The Λ+c/D0 ratio is also compared with model calculations including different implementations of charm quark hadronisation. The measured ratio is reproduced by models implementing a pure coalescence scenario, while adding a fragmentation contribution leads to an underestimation. The Λ+c nuclear modification factor, RAA, is also presented. The measured values of the RAA of Λ+c, Ds and non-strange D mesons are compatible within the combined statistical and systematic uncertainties. They show, however, a hint of a hierarchy (RD0AA<RDsAA<RΛ+cAA), conceivable with a contribution of recombination mechanisms to charm hadron formation in the medium.
A measurement of the production of prompt Λ+c baryons in Pb-Pb collisions at sNN−−−√=5.02 TeV with the ALICE detector at the LHC is reported. The Λ+c and Λ¯¯¯¯−c were reconstructed at midrapidity (|y|<0.5) via the hadronic decay channel Λ+c→pK0S (and charge conjugate) in the transverse momentum and centrality intervals 6<pT<12 GeV/c and 0-80%. The Λ+c/D0 ratio, which is sensitive to the charm quark hadronisation mechanisms in the medium, is measured and found to be larger than the ratio measured in minimum-bias pp collisions at s√=7 TeV and in p-Pb collisions at sNN−−−√=5.02 TeV. In particular, the values in p-Pb and Pb-Pb collisions differ by about two standard deviations of the combined statistical and systematic uncertainties. The Λ+c/D0 ratio is also compared with model calculations including different implementations of charm quark hadronisation. The measured ratio is reproduced by models implementing a pure coalescence scenario, while adding a fragmentation contribution leads to an underestimation. The Λ+c nuclear modification factor, RAA, is also presented. The measured values of the RAA of Λ+c, Ds and non-strange D mesons are compatible within the combined statistical and systematic uncertainties. They show, however, a hint of a hierarchy (RD0AA<RDsAA<RΛ+cAA), conceivable with a contribution of recombination mechanisms to charm hadron formation in the medium.
Λ+c production and baryon-to-meson ratios in pp and p–Pb collisions at √sNN = 5.02 TeV at the LHC
(2021)
The prompt production of the charm baryon Λ+c and the Λ+c/D0 production ratios were measured at midrapidity with the ALICE detector in pp and p-Pb collisions at sNN−−−√=5.02TeV. These new measurements show a clear decrease of the Λ+c/D0 ratio with increasing transverse momentum (pT) in both collision systems in the range 2<pT<12 GeV/c, exhibiting similarities with the light-flavour baryon-to-meson ratios p/π and Λ/K0S. At low pT, predictions that include additional colour-reconnection mechanisms beyond the leading-colour approximation; assume the existence of additional higher-mass charm-baryon states; or include hadronisation via coalescence can describe the data, while predictions driven by charm-quark fragmentation processes measured in e+e− and e−p collisions significantly underestimate the data. The results presented in this letter provide significant evidence that the established assumption of universality (colliding-system independence) of parton-to-hadron fragmentation is not sufficient to describe charm-baryon production in hadronic collisions at LHC energies.
Λ+c production and baryon-to-meson ratios in pp and p–Pb collisions at √sNN = 5.02 TeV at the LHC
(2021)
The prompt production of the charm baryon Λ+c and the Λ+c/D0 production ratios were measured at midrapidity with the ALICE detector in pp and p-Pb collisions at sNN−−−√=5.02TeV. These new measurements show a clear decrease of the Λ+c/D0 ratio with increasing transverse momentum (pT) in both collision systems in the range 2<pT<12 GeV/c, exhibiting similarities with the light-flavour baryon-to-meson ratios p/π and Λ/K0S. At low pT, predictions that include additional colour-reconnection mechanisms beyond the leading-colour approximation; assume the existence of additional higher-mass charm-baryon states; or include hadronisation via coalescence can describe the data, while predictions driven by charm-quark fragmentation processes measured in e+e− and e−p collisions significantly underestimate the data. The results presented in this letter provide significant evidence that the established assumption of universality (colliding-system independence) of parton-to-hadron fragmentation is not sufficient to describe charm-baryon production in hadronic collisions at LHC energies.
Λ+c production and baryon-to-meson ratios in pp and p–Pb collisions at √sNN = 5.02 TeV at the LHC
(2021)
The prompt production of the charm baryon Λ+c and the Λ+c/D0 production ratios were measured at midrapidity with the ALICE detector in pp and p-Pb collisions at sNN−−−√=5.02TeV. These new measurements show a clear decrease of the Λ+c/D0 ratio with increasing transverse momentum (pT) in both collision systems in the range 2<pT<12 GeV/c, exhibiting similarities with the light-flavour baryon-to-meson ratios p/π and Λ/K0S. At low pT, predictions that include additional colour-reconnection mechanisms beyond the leading-colour approximation; assume the existence of additional higher-mass charm-baryon states; or include hadronisation via coalescence can describe the data, while predictions driven by charm-quark fragmentation processes measured in e+e− and e−p collisions significantly underestimate the data. The results presented in this letter provide significant evidence that the established assumption of universality (colliding-system independence) of parton-to-hadron fragmentation is not sufficient to describe charm-baryon production in hadronic collisions at LHC energies.
Λ+c production and baryon-to-meson ratios in pp and p–Pb collisions at √sNN = 5.02 TeV at the LHC
(2020)
The prompt production of the charmed baryon Λ+c and the Λ+c/D0 production ratios were measured at midrapidity with the ALICE detector in pp and p-Pb collisions at sNN−−−√=5.02TeV. These new measurements show a clear decrease of the Λ+c/D0 ratio with increasing transverse momentum (pT) in both collision systems in the range 2<pT<12 GeV/c, exhibiting similarities with the light-flavour baryon-to-meson ratios p/π and Λ/K0S. At low pT, predictions that include additional colour-reconnection mechanisms beyond the leading-colour approximation; assume the existence of additional higher-mass charmed-baryon states; or include hadronisation via coalescence can describe the data, while predictions driven by charm-quark fragmentation processes measured in e+e− and e−p collisions significantly underestimate the data. The results presented in this letter provide significant evidence that the established assumption of universality (colliding-system independence) of parton-to-hadron fragmentation is not sufficient to describe charmed-baryon production in hadronic collisions at LHC energies.
In April and May 2012 data on Au+Au collisions at beam energies of Ekin = 1.23A GeV were recorded with the High Acceptance Di-Electron Spectrometer, which is located at the GSI Helmholtz Center for Heavy Ion Research in Darmstadt, Germany. At this beam energy all hadrons containing strangeness are produced below their elementary production threshold. The required energy is not available in binary NN collisions but must be provided by the system e.g. through multi-particle interactions or medium effects like a modified in-medium potential (e.g. KN/ΛN potential). Thus, a high sensitivity to these medium effects is expected in the investigated system.
The baryon-dominated systems created in relativistic heavy-ion collisions (HIC) at SIS18 energies reach densities of about 2-3 times ground state density p0 and may be similar to the properties of matter expected in the inner core of neutron stars. It is in particular the behavior of hadrons containing strangeness, i.e. kaons and hyperons, and their potentials in the dense medium which may have severe implications on astrophysical objects and processes. As ab-initio calculations of quantum chromodynamics (QCD) cannot be performed rigorously on the lattice at finite baryo-chemical potentials due to the fermion sign problem, effective descriptions have to be used in order to model properties of dense systems and the involved particles. The only way to access the in-medium potential of strange hadrons above nuclear ground state density p0 is by comparing data from relativistic HIC to such effective microscopic models. Up to now, not much data on neutral kaons and Λ hyperons are available from heavy collision systems close to their NN production threshold. These two electromagnetically uncharged strange hadrons are in particular well suited to study their potential in a dense nucleon-dominated environment as their kinematic spectra are not affected by Coulomb interactions.
Purpose: Recent studies demonstrated a contribution of adrenoceptors (ARs) to osteoarthritis (OA) pathogenesis. Several AR subtypes are expressed in joint tissues and the β2-AR subtype seems to play a major role during OA progression. However, the importance of β2-AR has not yet been investigated in knee OA. Therefore, we examined the development of knee OA in β2-AR-deficient (Adrb2-/-) mice after surgical OA induction.
Methods: OA was induced by destabilization of the medial meniscus (DMM) in male wildtype (WT) and Adrb2-/- mice. Cartilage degeneration and synovial inflammation were evaluated by histological scoring. Subchondral bone remodeling was analyzed using micro-CT. Osteoblast (alkaline phosphatase - ALP) and osteoclast (cathepsin K - CatK) activity were analyzed by immunostainings. To evaluate β2-AR deficiency-associated effects, body weight, sympathetic tone (splenic norepinephrine (NE) via HPLC) and serum leptin levels (ELISA) were determined. Expression of the second major AR, the α2-AR, was analyzed in joint tissues by immunostaining.
Results: WT and Adrb2-/- DMM mice developed comparable changes in cartilage degeneration and synovial inflammation. Adrb2-/- DMM mice displayed elevated calcified cartilage and subchondral bone plate thickness as well as increased epiphyseal BV/TV compared to WTs, while there were no significant differences in Sham animals. In the subchondral bone of Adrb2-/- mice, osteoblasts activity increased and osteoclast activity deceased. Adrb2-/- mice had significantly higher body weight and fat mass compared to WT mice. Serum leptin levels increased in Adrb2-/- DMM compared to WT DMM without any difference between the respective Shams. There was no difference in the development of meniscal ossicles and osteophytes or in the subarticular trabecular microstructure between Adrb2-/- and WT DMM as well as Adrb2-/- and WT Sham mice. Number of α2-AR-positive cells was lower in Adrb2-/- than in WT mice in all analyzed tissues and decreased in both Adrb2-/- and WT over time.
Conclusion: We propose that the increased bone mass in Adrb2-/- DMM mice was not only due to β2-AR deficiency but to a synergistic effect of OA and elevated leptin concentrations. Taken together, β2-AR plays a major role in OA-related subchondral bone remodeling and is thus an attractive target for the exploration of novel therapeutic avenues.
No disease modifying therapy is currently available for Parkinson’s disease (PD), the second most common neurodegenerative disease. The long non-motor prodromal phase of PD is a window of opportunity for early detection and intervention. However, we lack the pathophysiological understanding to develop selective biomarkers and interventions. By developing a mutant α-synuclein selective-overexpression mouse model of prodromal PD, we identified a cell-autonomous selective Kv4 channelopathy in dorsal motor nucleus of the vagus (DMV) neurons. This functional remodeling of intact DMV neurons leads to impaired pacemaker function in vitro and in vivo, which in turn reduces gastrointestinal motility which is a common, very early symptom of prodromal PD. We show for the first time a causal chain of events from α-synuclein via a biophysical dysfunction of specific neuronal populations to a clinically relevant prodromal symptom. These findings can facilitate the rational design of clinical biomarkers to identify people at risk for PD.
α-ketoglutarate dehydrogenase inhibition counteracts breast cancer-associated lung metastasis
(2018)
Metastasis formation requires active energy production and is regulated at multiple levels by mitochondrial metabolism. The hyperactive metabolism of cancer cells supports their extreme adaptability and plasticity and facilitates resistance to common anticancer therapies. In spite the potential relevance of a metastasis metabolic control therapy, so far, limited experience is available in this direction. Here, we evaluated the effect of the recently described α-ketoglutarate dehydrogenase (KGDH) inhibitor, (S)-2-[(2,6-dichlorobenzoyl) amino] succinic acid (AA6), in an orthotopic mouse model of breast cancer 4T1 and in other human breast cancer cell lines. In all conditions, AA6 altered Krebs cycle causing intracellular α-ketoglutarate (α-KG) accumulation. Consequently, the activity of the α-KG-dependent epigenetic enzymes, including the DNA demethylation ten-eleven translocation translocation hydroxylases (TETs), was increased. In mice, AA6 injection reduced metastasis formation and increased 5hmC levels in primary tumours. Moreover, in vitro and in vivo treatment with AA6 determined an α-KG accumulation paralleled by an enhanced production of nitric oxide (NO). This epigenetically remodelled metabolic environment efficiently counteracted the initiating steps of tumour invasion inhibiting the epithelial-to-mesenchymal transition (EMT). Mechanistically, AA6 treatment could be linked to upregulation of the NO-sensitive anti-metastatic miRNA 200 family and down-modulation of EMT-associated transcription factor Zeb1 and its CtBP1 cofactor. This scenario led to a decrease of the matrix metalloproteinase 3 (MMP3) and to an impairment of 4T1 aggressiveness. Overall, our data suggest that AA6 determines an α-KG-dependent epigenetic regulation of the TET–miR200–Zeb1/CtBP1–MMP3 axis providing an anti-metastatic effect in a mouse model of breast cancer-associated metastasis.
Es werden Schwingkreismodelle angegeben, deren Säkulargleichungen mit denen formal identisch sind, die sich bei der Anwendung der Methode der Moleküleigenfunktionen auf das Problem der π -Elektronenzustände in Molekülen ungesättigter und aromatischer Kohlenwasserstoffe ergeben. Damit ergibt sich die Möglichkeit, die quantenmechanischen Säkularprobleme durch Messung der Eigenfrequenzen der Modelle zu bestimmen.
1. Electron micrographs of ultra-thin sections of Staphylococcus aureus and Micrococcus lysodeikticus in Vestopal as embedding medium disclose a multiplicity of DNA containing threads with varying interparticular distances.
2. The diameter of these threads is about one tenth of the average optimal section thickness.
3. This section thickness inevitably is implicated in the visualization of the internal distances between the threads as well as in some common trends in the DNA pool, a fact that has to be accounted for in the analysis of the macromolecules.
4. By spreading lysozyme protoplasts of M. lysodeikticus on a water-air interface in a Langmuir trough and by transferring this surface layer to carbon supported Formvar films, two-dimensional systems can be demonstrated which as a thread of constant width comprise the total DNA content of one microorganism each.
5. Such a macromolecular system shows equally shaped, coiled loops in a peripheral zone and many crossings towards the center. Branching of threads never has been observed so far.
From this evidence we conlude:
a) Intracellular DNA in these bacteria seems to exist in one pool as a “woolen ball” which is centered in the cytoplasm as a more or less dense object.
b) This “woolen ball“ embodies the total amount of DNA most probably as one single threadlike unit.
6. Partial destruction of the thread system of protoplasts will result upon changing optimal spreading conditions.
7. The same kind of destruction is shown upon isolation of the DNA from protoplasts, the length of the threads being an inverse function of the number of precipitation steps showing purification.
ß-Hydroxybutyrate (BHB) is a ketone body formed in high amounts during lipolysis and fasting. Ketone bodies and the ketogenic diet were suggested as neuroprotective agents in neurodegenerative disease. In the present work, we induced transient ischemia in mouse brain by unilaterally occluding the middle cerebral artery for 90 min. BHB (30 mg/kg), given immediately after reperfusion, significantly improved the neurological score determined after 24 h. In isolated mitochondria from mouse brain, oxygen consumption by the complexes I, II and IV was reduced immediately after ischemia but recovered slowly over 1 week. The single acute BHB administration after reperfusion improved complex I and II activity after 24 h while no significant effects were seen at later time points. After 24 h, plasma and brain BHB concentrations were strongly increased while mitochondrial intermediates (citrate, succinate) were unchanged in brain tissue. Our data suggest that a single administration of BHB may improve mitochondrial respiration for 1–2 days but not for later time points. Endogenous BHB formation seems to complement the effects of exogenous BHB administration.
Alzheimer’s Disease (AD) is the most common neurodegenerative disorder marked by progressive loss of memory and cognitive ability. The pathology of AD is characterised by the presence of amyloid plaques, intracellular neurofibrillary tangles and pronounced cell death. The aim of this thesis was to investigate pathways involved in the Aß cascade of neurodegeneration. Since novel findings indicate that already this Aß species exerts neurotoxic effects long before hyperphosphorylated tau, neurofibrillary tangles and extracellular Aß plaques appear, the investigations were accomplished with specific regard to the effects of intracellular Aß. The Swedish double mutation in the APP gene results in six- to eightfold increased Aß production of both Aß1-40 and Aß1-42 compared to human wildtype APP cells (APPwt). Data obtained from PC12 cells indicate that it is possible to specifically increase the Aß load without enhancing APP expression levels. On the basis of these findings, it seemed possible to investigate dose-dependent effects of Aß in multiple experimental designs. These assay designs were created in order to mimick different in-vivo situations that are discussed to occur in AD patients: APPsw PC12 cells exhibit low physiological concentrations of Aß within picomolar range in contrast to APPsw HEK cells, expressing Aß levels within the nanomolar range. Of note, the APPsw HEK cells showed a specific and highly significant increase in the intracellular accumulation of insoluble Aß1-42. Moreover, an intracellular accumulation of Aß and APP was found in the mitochondria of the HEK APPsw cells suggesting a direct impact on mitochondrial function on these cells. This effect might finally lead to disturbances in the energy metabolism of the cell or to increased cell death. Furthermore, baseline g- and ß-secretase activity was assessed since these enzymes represent promising therapeutic targets to slow or halt the disease process. As expected, ß-secretase activity was significantly elevated in all APPsw cell lines. This might be due to the proximity of the Swedish double mutation next to the N-terminus of the Aß sequence. Interestingly, g-secretase activity was similarly increased in PC12 APPsw cells. In addition, the toxicity of different Aß species was investigated in SY5Y and PC12 cells with regard to their effect on cellular viability mirrored by mitochondrial activity using MTT assay. Here, it turned out that not monomers, but already dimers are neurotoxic correlates. Fibrillar Aß species showed the highest toxicity. In the next step, SY5Y cells forming endogenous, dimeric APP and Aß were investigated. In accordance with previous findings, these cells showed a decreased MTT reduction potential in comparison to APPwt and control SY5Y cells reflecting a decrease of cellular viability. The impaired energy metabolism of the cells was even more drastically mirrored by reduced baseline ATP levels. In the second part of this thesis, the expression and intracellular distribution of Bcl-2 family proteins and pro-apoptotic mitochondrial factors under baseline conditions and during oxidative stress were analyzed in the APPwt and APPsw bearing cells. The most prominent finding was the reduction of expression levels of the anti-apoptotic factor Bcl-xL in the cytosolic fractions of APPwt and APPsw PC12 cells. This might indicate that a lack of anti-apoptotic factors or their altered intracellular distribution, rather than an increase in caspase-dependent pro-apoptotic factors, could be responsible for the increased vulnerability of APPwt- and APPsw-transfected PC12 cells against oxidative stress. Since total Bcl-xL expression was unaffected in PC12 cells, in contrast to APPwt and APPsw-expressing SY5Y and HEK cells revealing significantly decreased Bcl-xL expression levels. Thus, alterations in Bcl-xL distribution seem to be an early event in the disease process. Increasing Bcl-xL expression might potentially be one promising strategy for AD modification. PC12 and HEK cells bearing APPsw or APPwt were treated with the potent g-secretase inhibitor DAPT. Of note, DAPT did not only efficiently block Aß production, but additionally led to an elevation of the MTT reduction potential, reflecting an increase in cellular viability. As another disease-modifying strategy, several efforts are undertaken to ameliorate AD-relevant symptoms by the treatment with nerve growth factor (NGF). Generally, it is known that substituted pyrimidines have modest growth-promoting effects. Here, KP544, a novel substituted pyrimidine, was characterised. This drug increased MTT reduction potential in terminally differentiated and undifferentiated PC12 cells. Furthermore, treatment with KP544 led to a reduction in Aß1-40 secretion. Thus, one may conclude that the target of KP544, GSK-3ß, represents a connecting link between the two main pathological hallmarks of AD and might thus be a very promising therapeutic target for AD.
In 2014, 56 localities in four provinces of Lesser Himalaya in Pakistan were studied. A total of 28 species have been recorded. A female of the data deficient, threatened species Coeliccia vacca was recorded from Charhaan. The record of Drepanosticta carmichaeli is a new addition to the list of Odonata of Pakistan, and expand the range of this species further to the west. The taxonomical status of Ischnura aurora aurora – considered common in Pakistan, following baseline literature of Fraser (1933) – now turns out to be Ischnura aurora rubilio.
Zvi Keren: his contribution to Israel's music scene : an interview in honor of his 85th birthday
(2002)
It is with great pride that I introduce a new section in this issue of Min-Ad: Israel Studies in Musicology, dedicated to interviews with musicians who have made major contributions to Israel’s music life. I am particularly pleased to inaugurate this section with an interview with our esteemed colleague (and in my case, teacher), Zvi Keren, a major figure in the development of Israel´s contemporary, jazz and light music. This interview is conducted by Alona Keren-Sagee, Zvi Keren´s daughter.
The Polyzoa discussed or described in this paper are all from fresh or brackish water. The majority are from the Tale Sap in the north-eastern part of the Malay Peninsula} but a few come from the Tai-Hu in the Kiangsu Province of China. I have also included notes on one Indian form. The following species are to be considered: ENTOPROCTA. Chitaspis athleticus, gen. et sp. nov., from the Tale Sap. CTENOSTOMATA. Alcyonidium mytili, Dalyell, from Indian estuaries, etc. Triticella pediceltata (Alder), from the Tale Sap. Bowerbankiacaudata, Hincks, from the Tale Sap and Perak. Paludicella elongata, Leidy, from the Tai-Hu. Paludicella pentagonalis, sp. nov., from the Tale Sap. Victorelta bengalensis, Annandale, from the Tale Sap. Hislopia cambodgiensis (Jullien), from the Tai-Hu. Hislopia malayensis. sp. nov., from Jalor in the Malay Peninsula. It will be as well to defer consideration of the biology and distribution of these species until I have been able to deal systematically with the Phylactolaemata and Cheilostomata collected on my tour. All that need be said here is that while the species of Paludicella and Hislopia are from fresh water, the others. on the list are from brackish water.
The genus Rhagovelia is revised for the region comprising Borneo, Celebes, and the Moluccas. Redescriptions are given for species previously described from the area, and 26 new species are described. Figures of the dorsal habitus and key characters are provided for all species, accompanied by a key to species and distribution maps. Species occurring in the region are divided into eight monophyletic intrageneric species groups, some of which also contain members outside the region, based primarily on wing venation, thoracic morphology, and genitalia. A zoogeographic analysis is presented based on the distribution of these groups within the Malay Archipelago and surrounding regions. We conclude that the present Rhagovelia fauna of the Malay Archipelago is derived from species which originated in continental Southeast Asia, Australia, and New Caledonia. Distinct lineages have entered the region from each of these three source areas, penetrating the archipelago with differing degrees of success and contributing to the fauna of each individual island to varying extents. Species groups of Asian origin do not extend beyond Celebes and the Lesser Sunda islands, while species groups of Papuan origin are absent in the Lesser Sundas and do not extend west of Borneo. Endemic species groups have also arisen on New Guinea, the Philippines, the north Moluccas, and Borneo. A section on ecology and behavior is provided, dealing in particular with the altitudinal segregation of species on individual islands. The following new Rhagovelia species are described: bacanensis, borneensis, celebensis, christenseni, grayi, hamdjahi, incognita, lorelinduana, meikdelyi, melanopsis, minahasa, obi, pruinosa, ranau, sabela, samardaca, samarinda, sarawakensis, silau, simulata, sondaica, sulawesiana, tawau, lebakang, unica, and wallacei. Rhagovelia mindanaoensis Hungerford and Matsuda 1961 is synonymized with Rhagovelia orientalis Lundblad 1937 (new synonymy).
Four species of mole crickets (Orthoptera: Gryllotalpidae) are known from the West Indies: Neocurtilla hexadactyla (Perty), Scapteriscus abbreviatus Scudder, S. didactylus (Latreille), and S. imitatus Nickle and Castner. All are adventive (not native). We document their distributions in West Indian islands/countries by use of records from the literature and examination of specimens. Scapteriscus abbreviatus has been suggested to have arrived in, and been transported about the West Indies in ship ballast (immigration). Based on records of arrival in various parts of the West Indies and the species’ inability to fly, this suggestion seems reasonable. Scapteriscus imitatus pparently was released in Puerto Rico as a result of mistaken identification (introduction – arriving with assistance from humans – although inadvertent), and has not expanded its range in the West Indies. Although the principal mode of dispersal for the other two species also has been suggested to be ship ballast, we present an alternative based on flight which would seem at least equally as plausible. We suggest that S. didactylus could have dispersed by flight from South America through the Lesser Antilles; likewise N. hexadactyla probably from the Yucatan Peninsula to Cuba, and from South America northward through the Lesser Antilles, in at least some localities assisted by wind. Our zoogeographical alternative, if correct, means that the natural range expansions of these latter two species began very long ago and without human assistance – they were not introduced recently to the West Indies.
Zinc finger proteins (ZNF) are a large group of transcription factors with diverse functions. We recently discovered that endothelial cells harbour a specific mechanism to limit the action of ZNF354C, whose function in endothelial cells is unknown. Given that ZNF354C has so far only been studied in bone and tumour, its function was determined in endothelial cells. ZNF354C is expressed in vascular cells and localises to the nucleus and cytoplasm. Overexpression of ZNF354C in human endothelial cells results in a marked inhibition of endothelial sprouting. RNA-sequencing of human microvascular endothelial cells with and without overexpression of ZNF354C revealed that the protein is a potent transcriptional repressor. ZNF354C contains an active KRAB domain which mediates this suppression as shown by mutagenesis analysis. ZNF354C interacts with dsDNA, TRIM28 and histones, as observed by proximity ligation and immunoprecipitation. Moreover, chromatin immunoprecipitation revealed that the ZNF binds to specific endothelial-relevant target-gene promoters. ZNF354C suppresses these genes as shown by CRISPR/Cas knockout and RNAi. Inhibition of endothelial sprouting by ZNF354C is dependent on the amino acids DV and MLE of the KRAB domain. These results demonstrate that ZNF354C is a repressive transcription factor which acts through a KRAB domain to inhibit endothelial angiogenic sprouting.
The following pages, initially prepared for limited circulation in 1961, contain brief extracts and summaries of those parts of Eugen ZintgraffÍs book Nord-Kamerun (1895), of most interest concerning the colonial Bamenda and Wum Division. ZintgraffÍs book, the first by a European about the Grassfields, has not been translated and is hard to get second-hand. In using these notes the following points should be borne in mind: ZintgraffÍs knowdie;ledge of Bali (Mungaka) and Hausa was very slight, and his discussions of character, motives and political institutions are consequently superficial and open to criticisms. He had no means of checking what he was told, or thought he was told. He had no previous knowledge of any similar culture and no training in ethnographical method. He was, however, a good observer, and his descriptions of tools, dress, weapons and the like, can be regarded as fairly reliable. Finally, it must be remembered that Zintgraff wrote the book to justify his own actions and to support that small but influential section of public opinion in Germany which favoured rapid imperial expansion. A full account of the actions and motives of ZintgraffÍs opponents in the Kamerun Governdie;ment and in the Colonial Bureau of the German Foreign Office has not been written: we only have one side of the story. But there are some suggestive points made in RudinÍs Germans in the Cameroons and others referred to in these notes. What is perhaps most striking about ZintgraffÍs account is the fact that the people of the Western Grassfields were not so isolated from one another or their neighbours as might be thought. A network of trade-friendships covered the country and big men exchanged gifts over long distances. These links must be set beside the insedie;curity due to raids and slave-catching, and are well worth investigation.
Iron deficiency (ID) is a common manifestation of inflammatory bowel disease (IBD), arising primarily due to chronic inflammation and/or blood loss. There is no gold standard for ID diagnosis, which is often complicated by concomitant inflammation. Zinc protoporphyrin (ZnPP) correlates with parameters of iron homeostasis and has been identified as a promising marker for ID, irrespective of inflammation. We investigated the diagnostic performance of ZnPP in ID, iron deficiency anemia, anemia of chronic disease and mixed anemia in a cross-sectional study in 130 patients with IBD. Different parameters were compared by receiver operator characteristic (ROC) analysis as detectors of iron-restricted erythropoiesis (IRE). IRE was detected in 91 patients (70.0%); fifty-nine (64.8%) had absolute ID and 23 (25.4%) functional ID. When inflammation was present, ZnPP was a more reliable sole biomarker of IRE than MCV, transferrin saturation (TSAT) or ferritin (AUC; 0.855 vs. 0.763, 0.834% and 0.772, respectively). The specificity of TSAT was significantly lower than ZnPP when inflammation was present (38% vs. 71%, respectively). We conclude that ZnPP is a reliable biomarker of functional ID in patients with IBD and more dependable than ferritin or TSAT, which are influenced by chronic inflammation. We propose that ZnPP may also have utility in patients with other chronic diseases.
The traffic AAA-ATPase PilF is essential for pilus biogenesis and natural transformation of Thermus thermophilus HB27. Recently, we showed that PilF forms hexameric complexes containing six zinc atoms coordinated by conserved tetracysteine motifs. Here we report that zinc binding is essential for complex stability. However, zinc binding is neither required for pilus biogenesis nor natural transformation. A number of the mutants did not exhibit any pili during growth at 64 °C but still were transformable. This leads to the conclusion that type 4 pili and the DNA translocator are distinct systems. At lower growth temperatures (55 °C) the zinc-depleted multiple cysteine mutants were hyperpiliated but defective in pilus-mediated twitching motility. This provides evidence that zinc binding is essential for the role of PilF in pilus dynamics. Moreover, we found that zinc binding is essential for complex stability but dispensable for ATPase activity. In contrast to many polymerization ATPases from mesophilic bacteria, ATP binding is not required for PilF complex formation; however, it significantly increases complex stability. These data suggest that zinc and ATP binding increase complex stability that is important for functionality of PilF under extreme environmental conditions.
Poetry is fragments of music thrown into the air. The primary job and aim of a poet is to create these musical notes, to play these musical notes, and the wind will take these fragment notes, sounds, musics into the ears of listeners. Zimbolicious Poetry Anthology, Volume 2 is one of those winds among many others. As we all are aware of, when the wind travels it has no boundaries, it collects, it deposits, it mixes things up; you never know where that leaf you see the wind carrying will eventually be deposited, is there another wind, another element that is going to move that leaf to another place... We firmly believe it is a good wind. It will be able to push our poetry making in Zimbabwe into other frontiers. Zimbolicious Poetry Anthology, Volume 2 continues from where we left off with the first Zimbolicious Poetry Anthology we created in 2016. In this Volume 2, we have 77 poems from 30 poets and translators, which include among others; experienced poets, academic poets, street poets, emergent poets, beginning poets, all telling stories associated with what all these poets refer to as home, that is, Zimbabwe. It is an ongoing debate on what is Zimbabwe, what we want our Zimbabwe to be socially, culturally, politically, thus we allowed every opinion space in this anthology, whether us editors agree with them or not. We have poets tackling issues to do with poetry, writing in general, art, place, identity, tradition, struggle, culture, gender, collective understanding, religion, individual, human rights and love, among others.
Zimbabwe: The Urgency of Now
(2015)
Zimbabwe: The Urgency of Now, is a follow-up creative non-fiction book to Zimbabwe: The Blame Game. It goes further than The Blame Game and focuses on Zimbabwe in the GNU entity, the 2013 elections, post elections and post GNU Zimbabwe, and Now. They are a myriad number of problems, issues, limitations that still unbundles Zimbabwe's push towards multiparty democracy, social justice, economic sanity and growth, and The Urgency of Now focuses on the solutions to these. It also tackles the land reform in South Africa, how this could be its biggest problem going forward. It goes further and tackles the larger Africa problem toward democracy, growth, stability and unity, and why the progress towards the United States of Africa has been moribund.
Zimbabwe: The Blame Game
(2013)
The Blame Game is a cycle of creative non-fiction pieces, pulling the readers through the politics of modern day Zimbabwe. Like in any game, there are players in this game, opposing each other. The game is told through the eyes of one of the players, thus it is subjective. It centres on truthfully trying to find who to blame for Zimbabwe's problems, and how to undo all these problems. Finding who to blame should be the beginning for the search of solutions. It encourages talking to each other, maybe about the wrongs we have done to each other, and genuinely trying to embrace and forgive each other. In trying to undo the problems in Zimbabwe, it also offers insight or solutions on a larger platform - Africa: particularly South Africa; that it might learn from other African countries that have imploded before it, how to solve its own problems.
Three years after the advent of Zimbabwe's Inclusive Government in February 2009, the country still awaits the elections that people hope will lead to a more enduring political settlement. Zimbabwe: Mired in Transition reviews the experience of recent years assesses the progress that has been made. What is the public mood, and how has it changed? What steps have been taken to reform the media? How important is a new constitution. Although the economy has stabilised to some extent with the adoption of a multi-currency regime, industrial and agricultural production are depressed, and investment inflows are limited; what spaces exist for fiscal reform? Are local authority structures and the state bureaucracy equipped to handle the tasks that will ne asked of them? In terms of two important areas, the book extends its analysis further back than 2009. First, is the issue of emigration. Estimates of the number of Zimbabweans in the diaspora range from three to four million; what impact us this having on national development, and to what extent might the trend of migration be reversed? The second concerns young people, the chapter on which concludes: 'We already have a 'lost generation' - those who were once called the 'born frees'. Unless positive changes are made, we will still have another'. This collection of eleven essays examines in detail some of the pressing questions which Zimbabweans must ask as they chart a way forward.
At Independence in 1980, Julius Nyerere called Zimbabwe 'the jewel of Africa', and cautioned its new leaders not to tarnish it. Tragically, they paid no heed to Africa's esteemed elder statesmen. Arguably - and only if one ignores the carnage of Gukurahundi - the first decade was a developmental one, with resources being used prudently to benefit the formerly disadvantaged majority population. However, the 1990s witnessed a transition from a developmental to a predatory leadership which saw Zimbabwe cross the millennial line in crisis, where it has remained ever since. While many African countries have moved forward over the last three decades, Zimbabwe has gone relentlessly backwards, save for the four-year interregnum of the tripartite coalition government, 2009-2013. Virtually all development indicators point in the wrong direction and the crisis of poverty, unemployment, and the erosion of health. education and other public goods continues unabated. The imperatives of political survival and power politics supersede those of sound economics and public welfare. Moreover, unless good politics are conjoined with a sound people-first policy, the country will continue sliding downhill. Zimbabwe's Trajectory tells the story of the country's post-independence dynamics and its recent descent into becoming one of the three most unhappy countries in the world.
The ongoing crisis in Zimbabwe has led to an unprecedented exodus of over a million desperate people from all strata of Zimbabwean society. The Zimbabwean diaspora is now truly global in extent. Yet rather than turning their backs on Zimbabwe, most maintain very close links with the country, returning often and remitting billions of dollars each year. Zimbabwe's Exodus. Crisis, Migration, Survival is written by leading migration scholars many from the Zimbabwean diaspora. The book explores the relationship between Zimbabwe's economic and political crisis and migration as a survival strategy. The book includes personal stories of ordinary Zimbabweans living and working in other countries, who describe the hotility and xenophobia they often experience.
Zimbabwe's Cultural Heritage
(2005)
' Zimbabwe's Cultural Heritage won first prize in the Zimbabwe Book Publishers Association Awards in 2006 for Non-fiction: Humanities and Social Sciences. It is a collection of pieces of the culture of the Ndebele, Shona, Tonga, Kalanga, Nambiya, Xhosa and Venda. The book gives the reader an insight into the world view of different peoples, through descriptions of their history and life events such as pregnancy, marriage and death. ''...the most enduring book ever on Zimbabwean history. This book will help people change their attitude towards each other in Zimbabwe.'' - Zimbabwe Book Publishers Association Awards citation'
Zimbabwe Will Never be a Colony Again! : Sanctions and Anti-Imperialist Struggles in Zimbabwe
(2019)
This is a thought-provoking original book, based on a wealth of empirical case studies of how Zimbabwe experienced illegal economic sanctions. It is a study of how the humanly constructed obstructions - from external remittances/finance flows into the country to finance embargos or total financial blockages - are deliberately created by so-called 'powerful' governments to deal with an 'errand' country. The infamous Zimbabwe Democracy Economic Recovery Act of 2001 (ZDERA) is part of a raft of punitive measures and discourses that the USA, UK and Europe used to make the economy, in the words of US's Chester Crooker 'scream'. It is the same 'powerful' countries who allow their Multinational Corporations to loot while they impose sanctions against African governments and their peoples to make them scream. The book is an insightful contribution on Africa's contemporary post-colonial liberation politics of development economics. It focuses on Zimbabwe as a synthesis of microcosmic study that provides accessible in-depth analysis of key aspects of sanctions as a weapon of control wielded by the so-called 'powerful' governments of the Global North. Zimbabwe was clobbered with post-independence economic sanctions after its land reform programme, which benefitted its mostly colonially dispossessed African citizens. The land reform was intended as a reversal of colonial injustice and a counter restitutive measure against imperialism. The book invites the reader to see power differently: as compassion and the capacity to right past wrongs by protecting all and sundry from inequality and poverty. Sanctions, even when called targeted, are non-discriminatory as they affect ordinary citizens with the same ferocity and savagery as against intended target, albeit often missing the target. Sanctions are lethal. Sanctions are a graveyard for the poor, weak and vulnerable. This is an idea of power that the Global North failed to grasp when they decided to punish the Mugabe government for daring to contemplate justice and restitution.
Zhero
(2011)
An inspiring and intriguing tale of heroism, Zhero's quest for education and self-worth takes him from the rustic village of Amabra to the cities of Port Harcourt and Lagos. Armed with a determination to succeed against all odds, his quest unearths a malignant problem in the society, which is the degradation and loss of human values. Vincent Egbuson's book is compendium of issues pervading contemporary Nigerian society. It beckons on its readers to emulate acts of kindness and self-sacrifice.
Background The synchrony hypothesis postulates that precise temporal synchronization of different pools of neurons conveys information that is not contained in their firing rates. The synchrony hypothesis had been supported by experimental findings demonstrating that millisecond precise synchrony of neuronal oscillations across well separated brain regions plays an essential role in visual perception and other higher cognitive tasks [1]. Albeit, more evidence is being accumulated in favour of its role as a binding mechanism of distributed neural responses, the physical and anatomical substrate for such a dynamic and precise synchrony, especially zero-lag even in the presence of non-negligible delays, remains unclear. Here we propose a simple network motif that naturally accounts for zero-lag synchronization for a wide range of temporal delays [3]. We demonstrate that zero-lag synchronization between two distant neurons or neural populations can be achieved by relaying the dynamics via a third mediating single neuron or population. Methods We simulated the dynamics of two Hodgkin-Huxley neurons that interact with each other via an intermediate third neuron. The synaptic coupling was mediated through alpha-functions. Individual temporal delays of the arrival of pre-synaptic potentials were modelled by a gamma distribution. The strength of the synchronization and the phase-difference between each individual pairs were derived by cross-correlation of the membrane potentials. Results In the regular spiking regime the two outer neurons consistently synchronize with zero phase lag irrespective of the initial conditions. This robust zero-lag synchronization naturally arises as a consequence of the relay and redistribution of the dynamics performed by the central neuron. This result is independent on whether the coupling is excitatory or inhibitory and can be maintained for arbitrarily long time delays (see Fig. 1). Conclusion We have presented a simple and extremely robust network motif able to account for the isochronous synchronization of distant neural elements in a natural way. As opposed to other possible mechanisms of neural synchronization, neither inhibitory coupling, gap junctions nor precise tuning of morphological parameters are required to obtain zero-lag synchronized neuronal oscillation.
Some requirements for a VERBMOBIL system capable of processing Japanese dialogue input have been explored. Based on a pilot study in the VERBMOBIL domain, dialogues between 2 participants and a professional Japanese interpreter have been analyzed with respect to a very typical and frequent feature: zero pronouns. Zero pronouns in Japanese texts or dialogues as well as overt pronouns in English texts or dialogues are an important element of discourse coherence. As to translation, this difference in the use of pronouns is a case of translation mismatch: information not explicitly expressed in the source language is needed in the target language. (Verb argument positions, normally obligatory in English, are rather frequently omitted in Japanese. Furthermore, verbs in Japanese are not marked with respect to features necessary for pronoun selection in English.)
Zero Point Soldier
(2019)
It took two years for this collection of poems to see the light of day. Two years. Two whole years. But two whole years of thinking, feeling and working through and from one of the strangest and certainly most torturous facts of life on Earth, and one of the least explored themes in the world of the modern woman of Africa, or my world, at least. This is the fact of Death. But not the fact of the death of all. Not the fact of the death of any. It is that of the modern man, the man, of Africa.
The dynamical quantum Zeno effect is studied in the context of von Neumann algebras. It is shown that the Zeno dynamics coincides with the modular dynamics of a localized subalgebra. This relates the modular operator of that subalgebra to the modular operator of the original algebra by a variant of the Kato-Lie-Trotter product formula.
Presentation at the Università di Pisa, Pisa, Itlay 3 July 2002, the conference on Irreversible Quantum Dynamics', the Abdus Salam ICTP, Trieste, Italy, 29 July - 2 August 2002, and the University of Natal, Pietermaritzburg, South Africa, 14 May 2003. Version of 24 April 2003: examples added; 16 December 2002: revised; 12 Sptember 2002. See the corresponding papers "Zeno Dynamics of von Neumann Algebras", "Zeno Dynamics in Quantum Statistical Mechanics" and "Mathematics of the Quantum Zeno Effect"
We study the quantum Zeno effect in quantum statistical mechanics within the operator algebraic framework. We formulate a condition for the appearance of the effect in W*-dynamical systems, in terms of the short-time behaviour of the dynamics. Examples of quantum spin systems show that this condition can be effectively applied to quantum statistical mechanical models. Furthermore, we derive an explicit form of the Zeno generator, and use it to construct Gibbs equilibrium states for the Zeno dynamics. As a concrete example, we consider the X-Y model, for which we show that a frequent measurement at a microscopic level, e.g. a single lattice site, can produce a macroscopic effect in changing the global equilibrium. PACS - Klassifikation: 03.65.Xp, 05.30.-d, 02.30. See the corresponding papers: Schmidt, Andreas U.: "Zeno Dynamics of von Neumann Algebras" and "Mathematics of the Quantum Zeno Effect" and the talk "Zeno Dynamics in Quantum Statistical Mechanics" - http://publikationen.ub.uni-frankfurt.de/volltexte/2005/1167/