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Species’ functional traits set the blueprint for pair-wise interactions in ecological networks. Yet, it is unknown to what extent the functional diversity of plant and animal communities controls network assembly along environmental gradients in real-world ecosystems. Here we address this question with a unique dataset of mutualistic bird–fruit, bird–flower and insect–flower interaction networks and associated functional traits of 200 plant and 282 animal species sampled along broad climate and land-use gradients on Mt. Kilimanjaro. We show that plant functional diversity is mainly limited by precipitation, while animal functional diversity is primarily limited by temperature. Furthermore, shifts in plant and animal functional diversity along the elevational gradient control the niche breadth and partitioning of the respective other trophic level. These findings reveal that climatic constraints on the functional diversity of either plants or animals determine the relative importance of bottom-up and top-down control in plant–animal interaction networks.
The etiology of many diseases results from the dysregulation of inflammation. Understanding the molecular mechanisms controlling the inflammatory response is essential to formulate therapeutic strategies for the treatment of inflammatory conditions. In fact, substantial research has unveiled important aspects of the inflammatory machinery, both at the cellular and molecular levels. Recently, sphingolipids (Sph) have emerged as signaling molecules that regulate many cell functions, and ample evidence emphasizes their role in the regulation of inflammatory responses. ...
The thesis deals with the analysis and modeling of point processes emerging from different experiments in neuroscience. In particular, the description and detection of different types of variability changes in point processes is of interest.
A non-stationary rate or variance of life times is a well-known problem in the description of point processes like neuronal spike trains and can affect the results of further analyses requiring stationarity. Moreover, non-stationary parameters might also contain important information themselves. The goal of the first part of the thesis is the (further) development of a technique to detect both rate and variance changes that may occur in multiple time scales separately or simultaneously. A two-step procedure building on the multiple filter test (Messer et al., 2014) is used that first tests the null hypothesis of rate homogeneity allowing for an inhomogeneous variance and that estimates change points in the rate if the null hypothesis is rejected. In the second step, the null hypothesis of variance homogeneity is tested and variance change points are estimated. Rate change points are used as input. The main idea is the comparison of estimated variances in adjacent windows of different sizes sliding over the process. To determine the rejection threshold functionals of the Brownian motion are identified as limit processes under the null of variance homogeneity. The non-parametric procedure is not restricted to the case of at most one change point. It is shown in simulation studies that the corresponding test keeps the asymptotic significance level for a wide range of parameters and that the test power is remarkable. The practical applicability of the procedure is underlined by the analysis of neuronal spike trains.
Point processes resulting from experiments on bistable perception are analyzed in the second part of the thesis. Visual illusions allowing for than more possible perception lead to unpredictable changes of perception. In the thesis data from (Schmack et al., 2015) are used. A rotating sphere with switching perceived rotation direction was presented to the participants of the study. The stimulus was presented continuously and intermittently, i.e., with short periods of „blank display“ between the presentation periods. There are remarkable differences in the response patterns between the two types of presentation. During continuous presentation the distribution of dominance times, i.e., the intervals of constant perception, is a right-skewed and unimodal distribution with a mean of about five seconds. In contrast, during intermittent presentation one observes very long, stable dominance times of more than one minute interchanging with very short, unstable dominance times of less than five seconds, i.e., an increase of variability.
The main goal of the second part is to develop a model for the response patterns to bistable perception that builds a bridge between empirical data analysis and mechanistic modeling. Thus, the model should be able to describe both the response patterns to continuous presentation and to intermittent presentation. Moreover, the model should be fittable to typically short experimental data, and the model should allow for neuronal correlates. Current approaches often use detailed assumptions and large parameter sets, which complicate parameter estimation.
First, a Hidden Markov Model is applied. Second, to allow for neuronal correlates, a Hierarchical Brownian Model (HBM) is introduced, where perception is modeled by the competition of two neuronal populations. The activity difference between these two populations is described by a Brownian motion with drift fluctuating between two borders, where each first hitting time causes a perceptual change. To model the response patterns to intermittent presentation a second layer with competing neuronal populations (coding a stable and an unstable state) is assumed. Again, the data are described very well, and the hypothesis that the relative time in the stable state is identical in a group of patients with schizophrenia and a control group is rejected. To sum up, the HBM intends to link empirical data analysis and mechanistic modeling and provides interesting new hypotheses on potential neuronal mechanisms of cognitive phenomena.
Die Tagung rief dazu auf, die Verbindlichkeit von Versprechen als allgemeines Phänomen zu untersuchen, also zu ergründen, inwiefern man unabhängig von ihrer Ausgestaltung in konkreten Rechtsordnungen oder anderen Normensystemen von einer "vor-rechtlichen" Verbindlichkeit sprechen kann. Literarische Texte aller Zeiten bis hin zu den Mythen bezeugen die Bindung an das Wort als Urerfahrung, die von jeder gesellschaftlichen Konvention unabhängig erscheint. Ebenso kennen sie aber Verrat und offenen oder verdeckten Wortbruch, deren Folgen sie thematisieren. Strukturelle Verwandtschaften einerseits und gegenseitige Beeinflussung andererseits der literarischen und der rechtlichen Auseinandersetzung mit dem Versprechen sollten untersucht werden.
The standard implementation of the HRG model has been shown to be unable to describe all the available data on QCD matter. Here we show the balance of repulsive and attractive hadronic interactions on QCD thermodynamics through observables both calculated by lattice simulations and measured in experiment. Attractive interactions are mediated by resonance formation, which are here implemented through extra states predicted by the Quark Model, while repulsive interactions are modelled by means of Excluded Volume (EV) effects. Informations on flavour dependent effective sizes are extracted. It is found that EV effects are present in lattice QCD thermodynamics, and are essential for a comprehensive description of higher order fluctuations of conserved charges.
Background: Intracerebral haemorrhage growth is associated with poor clinical outcome and is a therapeutic target for improving outcome. We aimed to determine the absolute risk and predictors of intracerebral haemorrhage growth, develop and validate prediction models, and evaluate the added value of CT angiography.
Methods: In a systematic review of OVID MEDLINE—with additional hand-searching of relevant studies' bibliographies— from Jan 1, 1970, to Dec 31, 2015, we identified observational cohorts and randomised trials with repeat scanning protocols that included at least ten patients with acute intracerebral haemorrhage. We sought individual patient-level data from corresponding authors for patients aged 18 years or older with data available from brain imaging initially done 0·5–24 h and repeated fewer than 6 days after symptom onset, who had baseline intracerebral haemorrhage volume of less than 150 mL, and did not undergo acute treatment that might reduce intracerebral haemorrhage volume. We estimated the absolute risk and predictors of the primary outcome of intracerebral haemorrhage growth (defined as >6 mL increase in intracerebral haemorrhage volume on repeat imaging) using multivariable logistic regression models in development and validation cohorts in four subgroups of patients, using a hierarchical approach: patients not taking anticoagulant therapy at intracerebral haemorrhage onset (who constituted the largest subgroup), patients taking anticoagulant therapy at intracerebral haemorrhage onset, patients from cohorts that included at least some patients taking anticoagulant therapy at intracerebral haemorrhage onset, and patients for whom both information about anticoagulant therapy at intracerebral haemorrhage onset and spot sign on acute CT angiography were known.
Findings: Of 4191 studies identified, 77 were eligible for inclusion. Overall, 36 (47%) cohorts provided data on 5435 eligible patients. 5076 of these patients were not taking anticoagulant therapy at symptom onset (median age 67 years, IQR 56–76), of whom 1009 (20%) had intracerebral haemorrhage growth. Multivariable models of patients with data on antiplatelet therapy use, data on anticoagulant therapy use, and assessment of CT angiography spot sign at symptom onset showed that time from symptom onset to baseline imaging (odds ratio 0·50, 95% CI 0·36–0·70; p<0·0001), intracerebral haemorrhage volume on baseline imaging (7·18, 4·46–11·60; p<0·0001), antiplatelet use (1·68, 1·06–2·66; p=0·026), and anticoagulant use (3·48, 1·96–6·16; p<0·0001) were independent predictors of intracerebral haemorrhage growth (C-index 0·78, 95% CI 0·75–0·82). Addition of CT angiography spot sign (odds ratio 4·46, 95% CI 2·95–6·75; p<0·0001) to the model increased the C-index by 0·05 (95% CI 0·03–0·07).
Interpretation: In this large patient-level meta-analysis, models using four or five predictors had acceptable to good discrimination. These models could inform the location and frequency of observations on patients in clinical practice, explain treatment effects in prior randomised trials, and guide the design of future trials.
Funding: UK Medical Research Council and British Heart Foundation.
Three-dimensional (3D) nanomagnetism, where spin configurations extend into the vertical direction of a substrate plane allow for more complex, hierarchical systems and the design of novel magnetic effects. As an important step towards this goal, we have recently demonstrated the direct-write fabrication of freestanding ferromagnetic 3D nano-architectures of ferromagnetic CoFe in shapes of nano-tree and nano-cube structures by means of focused electron beam induced deposition. Here, we present a comprehensive characterization of the magnetic properties of these structures by local stray-field measurements using a high-resolution micro-Hall magnetometer. Measurements in a wide range of temperatures and different angles of the externally applied magnetic field with respect to the surface plane of the sensor are supported by corresponding micromagnetic simulations, which explain the overall switching behavior of in part rather complex magnetization configurations remarkably well. In particular, the simulations yield coercive and switching fields that are in good quantitative correspondence with the measured coercive and switching fields assuming a bulk metal content of 100 at % consisting of bcc Co 3 Fe. We show that thermally-unstable magnetization states can be repetitively prepared and their lifetime controlled at will, a prerequisite to realizing dynamic and thermally-active magnetic configurations if the building blocks are to be used in lattice structures.
Sömürgeciliğin farklı bakış açılarıyla sorunsallaştırıldığı postkolonyal düşünce, kimi yazarları derin bir etki altına alarak söz konusu yaklaşımlara ilişkin düşüncelerini yazınsal yapıtlarında yansıtma olarak açığa çıkmıştır. Bu yazarlardan biri olan çağdaş Alman Edebiyatının en önemli isimlerinden Uwe Timm, 1978 yılında kaleme aldığı ve 1904-1907 yılları arasında geçen sürede Almanya'nın söz konusu dönemde sömürgesi olan Güney Afrika'da yaşamakta olan yerliler ile Almanlar arasındaki mücadelenin konulaştırıldığı Morenga adlı tarihsel romanında kurguladığı Gottschalk karakterinin "Beyaz Kıta"dan "Kara Kıta"ya gelişiyle birlikte kişisel ve sosyal yaşamına ilişkin yaşadığı değişimleri gözler önüne sermiştir. Polonya asıllı İngiliz yazar Joseph Conrad ise, 1899 yılında yazdığı Karanlığın Yüreği adlı yapıtında, "Kara Kıta"ya bir iş için görevlendirilen Marlow'un kıtanın derinliklerinde beyazların yerlilere uyguladığı işkencelerle birlikte deneyimlediklerini anlatılaştırır. Bu bağlamda, postkolonyal kuram ışığında karşılaştırmalı ve metin içkin yöntemle irdelenecek olan söz konusu çalışmada öncelikle postkolonyalizmin bir kuram olarak ortaya çıkışı ve postkolonyal edebiyatın sınırlarına değinilecek, söz konusu iki yapıtta, Afrika topraklarına görevlendirilen başkahramanların kıtada kaldıkları süre boyunca geçirdiği değişim irdelenecek, bir sonuç değerlendirmesi yapılarak çalışma sonlandırılacaktır.
'Leutnant Gustl' als eine repräsentative Figur für die
Identitätsdefizite in der Gesellschaft
(2018)
In vorliegender Arbeit haben wir den Versuch unternommen, die Novelle mit dem Titel "Leutnant Gustl" von Arthur Schnitzler im Lichte der wissenschaftlichen Literatur mit dem deskriptiven Verfahren zu analysieren. Es geht darin um einen Konflikt zwischen der inneren Welt des kleinbürgerlichen Protagonisten der k.u.k. Monarchie der Jahrhundertwende, und der Gesellschaft, in der er lebt. Hier wird vorwiegend die Identitätskrise der Figur Leutnant Gustl, die mit seiner Umgebung zu tun hat, und die sich mit der Überwindung derselben auseinandergesetzt. Bei der Analyse wird nicht zuletzt auf die Fragen eingegangen, worin die Identitätsprobleme liegen, wie der Protagonist aus diesen Problemen herauszukommen versucht.
Lion Feuchtwanger (1884-1958) schrieb zahlreiche Gegenwartsromane, aber seinen Ruhm begründete er mit der historischen Dichtung, die er für die Aktivierung von Vernunft und Rationalität einsetzt. Sei es im Exil oder in der inneren Emigration, es war für Schriftsteller nicht einfach das Phänomen des "Nationalsozialismus" und vor allem Hitler als eine literarische Figur darzustellen. Um eine größere Leserzahl zu erreichen bevorzugte Lion Feuchtwanger historische und biographische Romane. In dem Roman "Der falschen Nero" übt er mittels Satire politische Kritik gegenüber den aktuellen Begebenheiten seiner Zeit aus.
Das Ziel dieser Studie ist, den Beitrag der Nachrichtentexte in den DaF-Lehrwerken zum Leseverstehen im Deutschen im Hinblick auf die Grammatik und Textlinguistik zu beschreiben. In dieser Studie wurde diese Frage beantwortet: Im GER befindet sich die Niveaustufe A1 mit bestimmten Semantisierungen. Wie ist diese Niveaustufe A1 jedoch als Wiederaufnahmestruktur aufgebaut? Dazu wurde ein Nachrichtentext aus DaF-Lehrwerken ausgewählt, die der Niveaustufe A1 entsprechen. Die Analyse der Wiederaufnahmestruktur wurde unter Berücksichtigung von Brinkers Kriterien (2010) durchgeführt, während die grammatischen Merkmale der Texte nach Laveau (1985) untersucht wurden. Die Wiederaufnahmestruktur des Textes wurde durch schematische Darstellungsform und Grafik gezeigt, die grammatische Struktur je nach Deklinationsform des Nomens. Der Nachrichtentext auf der Niveaustufe A1, der einer von den bei unserer Magisterarbeit in jeder Niveaustufe untersuchten Nachrichtentexten ist, wurde in dieser Studie repräsentativ behandelt. Die erhaltenen Befunde wurden im Hinblick auf das Leseverstehen im DaF-Unterricht ausgewertet. Den Ergebnissen nach ist der Nachrichtentext auf der Niveaustufe A1 grammatisch ein einfach strukturierter und textlinguistisch ein gut strukturierter Text. Darüber hinaus wurde nach der Analyse der Wiederaufnahmestruktur des Textes auf der Niveaustufe A1 festgestellt, dass die sprachliche Struktur "es" in der Aufgabe zum Leseverstehen eine wiederaufnehmende Funktion eingenommen hat, weil diese sprachliche Struktur auf den ganzen vorhergehenden Textabschnitt verweist. Es wird erwartet, dass ein Student über ein textlinguistisches Wissen verfügen müsste, um die Wiederaufnahme der Struktur "es" im Text verstehen zu können. In dieser Studie wurde vorgeschlagen, dass im DaF-Unterricht beim Leseverstehen die Textlinguistik und darauf bezogen die Wiederaufnahmestruktur thematisiert werden sollte, genau wie es bei den grammatischen Strukturen der Fall ist.
Traditional latency-limited trigger architectures typical for conventional experiments are inapplicable for the CBM experiment. Instead, CBM will ship and collect time-stamped data into a readout buffer in a form of a time-slice of a certain length and deliver it to a large computer farm, where online event reconstruction and selection will be performed. Grouping measurements into physical collisions must be performed in software and requires reconstruction not only in space, but also in time, the so-called 4-dimensional track reconstruction and event building. The tracks, reconstructed with 4D Cellular Automaton track finder, are combined into event-corresponding clusters according to the estimated time in the target position and the errors, obtained with the Kalman Filter method. The reconstructed events are given as inputs to the KF Particle Finder package for short-lived particle reconstruction. The results of time-based reconstruction of simulated collisions in CBM are presented and discussed in details.
Targeting for rare observables, the CBM experiment will operate at high interaction rates of up to 10 MHz, which is unprecedented in heavy-ion experiments so far. It requires a novel free-streaming readout system and a new concept of data processing. The huge data rates of the CBM experiment will be reduced online to the recordable rate before saving the data to the mass storage. Full collision reconstruction and selection will be performed online in a dedicated processor farm. In order to make an efficient event selection online a clean sample of particles has to be provided by the reconstruction package called First Level Event Selection (FLES).
The FLES reconstruction and selection package consists of several modules: track finding, track fitting, event building, short-lived particles finding, and event selection. Since detector measurements contain also time information, the event building is done at all stages of the reconstruction process. The input data are distributed within the FLES farm in a form of time-slices. A time-slice is reconstructed in parallel between processor cores. After all tracks of the whole time-slice are found and fitted, they are collected into clusters of tracks originated from common primary vertices, which then are fitted, thus identifying the interaction points. Secondary tracks are associated with primary vertices according to their estimated production time. After that short-lived particles are found and the full event building process is finished. The last stage of the FLES package is a selection of events according to the requested trigger signatures. The event reconstruction procedure and the results of its application to simulated collisions in the CBM detector setup are presented and discussed in detail.
Çeviri, birer eyleyen olarak çevirmenlerin yönlendirdiği bir eylemdir. Bu gerçek, bilgi teknolojilerinin bu uygulama sahasında varlıklarını yoğun biçimde hissettirdikleri günümüz çeviri dünyası içinde de geçerliliğini korumaktadır. İnsanın merkezde bulunduğu her uygulama sahasında olduğu gibi çeviri alanında da nesnel ölçütlerin bulunup uygulanabilmesi, beklenen ve arayışında olunan bir konu olagelmiştir.
Bugün özerk bir araştırma alanı olarak çeviribilim, salt araştırma alanında (pure research) çeviri olgusuna dâhil bütün boyutları betimlemeye ve buradan üst ilkelere ulaşmaya çalışırken, uygulamalı araştırma alanında (applied research) ise çeviri edimi ile ilgili nesnel ölçütler üretmeyi denemektedir. Bu yönüyle çeviribilimciler, çeviri eleştirisi, çeviri politikası, çeviri araçları alanlarında olduğu gibi akademik çeviri eğitiminde de nesnel ölçütleri aramaktadır.
Konu somut olarak çeviri uygulamalarının yaptırıldığı derslere indirgenirse, çeviri derslerinde metin seçiminin, bugün öznel gerekçelere dayandığı söylenebilir. Bu durum, bu çalışmada seçilen konunun sorunsallaştırılmasını önemli hale getirmektedir. Bu çalışmanın temel amacı, çeviri derslerinde metin seçiminin ölçütlerini saptamaya çalışmaktır.
With the change to one scientific name for pleomorphic fungi, generic names typified by sexual and asexual morphs have been evaluated to recommend which name to use when two names represent the same genus and thus compete for use. In this paper, generic names in Pucciniomycotina and Ustilaginomycotina are evaluated based on their type species to determine which names are synonyms. Twenty-one sets of sexually and asexually typified names in Pucciniomycotina and eight sets in Ustilaginomycotina were determined to be congeneric and compete for use. Recommendations are made as to which generic name to use. In most cases the principle of priority is followed. However, eight generic names in the Pucciniomycotina, and none in Ustilaginomycotina, are recommended for protection: Classicula over Naiadella, Gymnosporangium over Roestelia, Helicobasidium over Thanatophytum and Tuberculina, Melampsorella over Peridermium, Milesina over Milesia, Phragmidium over Aregma, Sporobolomyces over Blastoderma and Rhodomyces, and Uromyces over Uredo. In addition, eight new combinations are made: Blastospora juruensis, B. subneurophyla, Cronartium bethelii, C. kurilense, C. sahoanum, C. yamabense, Milesina polypodii, and Prospodium crusculum combs. nov.
Millions of Ghanaians live with diabetes, hypertension, stroke, cancers and other major chronic diseases. Millions more are at risk of getting these conditions. Individuals living with chronic conditions experience many disruptions, especially at the early stages of diagnosis and adjustment. The disruptions are physical (medical complications), psychological (depression), material (impoverishment), social (stigma) and spiritual (struggles with faith and trust). These experiences have an impact on family life and resources, with primary caregivers bearing similar disruptions to their chronically ill loved ones. While chronic conditions cannot be cured, many individuals hope for a cure. This hope drives healthcare seeking across different sectors of Ghanas vibrant pluralistic health system. When hope for a cure meets claims to cure within the herbalist and faith healing sectors, especially, the outcomes for individuals and their families can be catastrophic. The Ghanaian situation is mirrored in many African countries. It is estimated that African chronic non-communicable disease (NCD) prevalence, morbidity and mortality rates will rise faster than rates in Asia and Latin America over the coming decades. The long term and costly nature of NCDs has major implications for individuals, communities, health systems and governments. In this inaugural lecture, Professor Ama de-Graft Aikins discusses the psychology of chronic disease risk, experience and care in Africa. She makes a case for why the problem of NCDs needs to be examined through a psychological lens. She draws on her independent and collaborative work on diabetes representations and experiences among Ghanaians in Ghana and Europe, and the broader African and global health literature, to highlight the complex multi-level context of chronic disease risk, experience and care. She presents a synthesis of the evidence through the concepts of physical ills and ideological ills, arguing that both are interconnected and, as a result, must be addressed through interdisciplinary approaches. She concludes by offering practical solutions for reducing chronic disease risk and improving the quality of long-term experience and care in Ghana, using examples from countries that have implemented successful NCD interventions.
Kaum jemand hat sich in den 1950er und 1960er Jahre ähnlich intensiv für die strafrechtliche, aber auch die zivilgesellschaftliche Aufarbeitung der nationalsozialistischen Gewaltverbrechen eingesetzt wie Fritz Bauer. Dessen 50. Todestag am 1. Juli 2018 nahm das Fritz Bauer Institut zum Anlass, seinem Namensgeber zwei große Veranstaltungen zu widmen.
During a survey of the fishes in the region of the Wonga-Wongué Presidential Reserve, 14 new populations of the subgenus Chromaphyosemion Myers, 1924 were found. These observations extend the previously known distribution range of the subgenus 120 kilometres southward. None of these populations could be related to any described species. Based on the colouration of the males and females, together with a genetic marker (mitochondrial DNA cytochrome b sequences), the populations studied are grouped into six new species which are described in this article, all close to Aphyosemion alpha Huber, 1998 with which they share the presence of a black alpha-shaped mark on the pre- and post-opercular region. The group composed of A. alpha and the six new species is referred to here as the A. alpha species group. All the new species, A. aurantiacum Chirio, Legros & Agnèse sp. nov., A. barakoniense Chirio, Legros & Agnèse sp. nov., A. flammulatum Chirio, Legros & Agnèse sp. nov., A. flavocyaneum Chirio, Legros & Agnèse sp. nov., A. pusillum Chirio, Legros & Agnèse sp. nov. and A. rubrogaster Chirio, Legros & Agnèse sp. nov., are further unambiguously diagnosed by unique combinations of colour patterns, making it possible to generate an identification key for the A. alpha species group. It is likely that the coastal dunes of Wonga-Wongué that form a sandy relief, could have led to the fragmentation and then isolation of the hydrographical networks that flow into the Atlantic Ocean, making possible a significant number of allopatric speciations.