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Wissen angezapft: unterhaltsam, informativ – und ziemlich schräg : Frankfurter Bürgeruniversität
(2024)
Studieren kann man lernen – so lautet das Motto der »Schlüsselkompetenzen im Studium«. Dieses Angebot hilft Studierenden dabei, die vielen Anforderungen, die das Studieren mit sich bringt, zu meistern. Neben dem bisherigen Workshopangebot können Studierende jetzt auch jederzeit und von überall online auf Selbstlernmaterialien zugreifen, die im Projekt »Erfolgreich Lehren und Lernen – Vielfalt und Internationales im Studium« (ELLVIS) erstellt wurden.
Thomas Bowrey, who was an employee of the British colonial government, visited the Malay-speaking region at the end of the 17th century and published a dictionary of Malay (1701) which consists of 12,683 headwords. It is one of the oldest and largest collections of data on this language, which was the first language of the people he came into contact with while travelling through the Malay Peninsula, spending most of his time in harbours along its west coast. Malay, which was spoken in the various trading centres of this area (e.g. Penang, Malacca), had long previously begun to develop into a form of lingua franca during Bowrey’s stay there due to the fact that traders, especially those from Arabic countries (beginning in the 12th century), China (from the 15th century onwards), Portugal (since 1511), the Netherlands (since 1641), and less so from England, came into contact with Malays speaking their local dialects in the various trading posts in Malaya and probably began to become acquainted with the trade-language variant. Thus, Bowrey must have observed and recorded elements of both.
The data he collected is not limited to Malay variants spoken in coastal areas, but includes material from dialects which he encountered during his travels throughout the Malay Peninsula, though without, however, describing the locations in which he took notes on the lexicon and clauses. Not all of his material was written into manuscript form during his stay in Southeast Asia. A large part of his notes taken in situ were prepared for publication during his long journey home. His notes, which were used to print his dictionary, are in part kept in British libraries. Most of the material accessible to the public was studied during the preparation of this thesis.
Earlier works on this dictionary are quite limited in scope. They deal with very specific aspects such as the meanings of headwords found between the letters A and C (Rahim Aman, 1997 & 1998), and the work of Nor Azizah, who deals with the lexical change found in Bowrey’s dictionary between D and F, and syntactic and sociolinguistic aspects (Mashudi Kader, 2009), and collective nouns by Tarmizi Hasrah (2010). This study will discuss Bowrey’s dictionary as a whole in order to describe its contribution to our knowledge of linguistic and non-linguistic facts in 17th century Malaya. Besides analysing Malay synchronically, this thesis also deals with historical-comparative questions and asks whether Bowrey contributes to our knowledge of the changes to the Malay language between the 17th and 21st centuries.
In order to answer the research questions, this study not only relies on the dictionary in its entirety, but also on the notes found in British libraries as well as other material on early Malay, such as the Pigafetta list (1523), Houtman (1598–1603), and the Wilkinson dictionary (1901) as a complement to Bowrey’s dictionary; at the same time, the Malay Concordance Project (online), the SEAlang Project (online), Kamus Besar Bahasa Indonesia (online), and Kamus Dewan Edisi Keempat (2007) will represent modern Malay. It should be borne in mind that in contrast to the Thomas Bowrey dictionary (TBD), Kamus Dewan Edisi Keempat (KDE4) does not hold information on colloquial forms of Malay, many of which reflect features of lingua franca Malay. This study is divided into two different branches, namely the consideration of synchronic aspects and historical comparative aspects.
Finally, this study concludes that the Malay language in Thomas Bowrey’s dictionary is heavily influenced by both external and internal factors prevalent to the 17th century. The Malay language recorded in the Thomas Bowrey dictionary is very similar to modern Malay. The similarities between the Malay language of the 17th century and the Malay language of today are considerable, even though there are, of course, still some notable variances.
Highlights
• Out of the six edible pumpkin seeds found in Cameroonian C. sativus showed most potent anti-proliferative effects on prostate cells.
• Its oil conserved almost all the effects of raw seeds and prevented benign prostatic hyperplasia (BPH).
• It exhibited potent anti-inflammatory activities in rat with BPH.
Abstract
Pumpkin seeds are claimed to treat prostate tumour/cancer. The in vitro (ability to inhibit cell growth through MTT assay) and in vivo (ability to prevent testosterone-induced BPH in rats at the doses of 125, 250, 500 and 1000 mg/kg BW) of six edible pumpkin seeds found in Cameroonian were assessed. The endpoints were cell growth arrest, prostate mass and volume, prostatic epithelium height, prostatic proteins, prostate specific antigen (PSA) and inflammatory cytokines. In vitro, C. sativus seeds exhibited the most potent antiproliferative effects on DU145 and PC3 prostate cancer cells and its oil conserved almost all the effects of raw seeds. Further, it prevented the increased of prostate relative mass and volume, prostate epithelium height, PSA and testosterone dose-dependently compared to normal rats. This effect is thought to be mediated through antiandrogenic, estrogenic and anti-inflammatory activities, evidenced by a decreased in IL-1β, IL-6 and TNFα level. Overall, this results justify its traditional use.
Metahumans ist ein innovatives Framework für die Unreal Engine, das hochgradig realistische digitale Charaktere zur Verfügung stellt. Metahumans zeichnen sich durch eine vollständige Control Rig aus, die es Entwicklern ermöglicht, vorgefertigte Animationen zu nutzen und sie nach Bedarf anzupassen und zu erweitern.
Im Rahmen dieser wissenschaftlichen Arbeit wird die Anwendung von Metahumans in der virtuellen Umgebung der Unreal Engine 5 untersucht. Das Hauptziel besteht darin, die Fähigkeit eines Metahumans zu untersuchen, mittels eines herkömmlichen Virtual Reality Headsets mithilfe von Motion Tracking gesteuert und animiert zu werden. Dabei wird speziell auf die Verwendung von Inverse Kinematics als Methode zur Erzeugung möglichst natürlicher Bewegungsabläufe eingegangen. Zusätzlich wird angestrebt, die Interaktion zwischen verschiedenen Metahuman-Avataren in einer Online-Sitzung zu ermöglichen.
Um den Einfluss auf das Immersionserlebnis der Benutzerinnen und Benutzer zu analysieren, werden Probandinnen und Probanden eingeladen, ihre Nutzererfahrungen zu evaluieren. Zu diesem Zweck werden zwei vergleichbare Level erstellt: eines in der Unreal Engine mit Metahumans und das andere in Unity mit den Meta Avataren von Oculus.
Diese wissenschaftliche Untersuchung zielt darauf ab, ein umfassendes Verständnis für die Leistungsfähigkeit von Metahumans zu erlangen, insbesondere im Vergleich zu anderen Avatar-Systemen.
Wir untersuchen die regulatorischen Änderungen in der EU, die die Transparenz bei nachhaltigen Investitionen erhöhen sollen. Durch eine Untersuchung der Unterschiede zwischen ESG-Ratingagenturen bewerten wir Herausforderungen für Standardisierung und Konsens von Ratings. Unsere Analyse unterstreicht die Dringlichkeit klarerer ESG-Ratings für eine nachhaltige Invesitionslandschaft.
We delve into the EU's regulatory changes aimed at boosting transparency in sustainable investments. By examining disparities among ESG rating agencies, we assess how these differences challenge standardization and consensus. Our analysis underscores the critical need for clearer ESG assessments to guide the sustainable investment landscape.
Beyond well-established difficulties with working memory in individuals with attention deficit hyperactivity disorder (ADHD), evidence is emerging that other memory processes may also be affected. We investigated, first, which memory processes show differences in adults and adolescents with ADHD in comparison to control participants, focusing on working and short-term memory, initial learning, interference, delayed and recognition memory. Second, we investigated whether ADHD severity, co-occurring depressive symptoms, IQ and physical fitness are associated with the memory performance in the individuals with ADHD.
We assessed 205 participants with ADHD (mean age 25.8 years, SD 7.99) and 50 control participants (mean age 21.1 years, SD 5.07) on cognitive tasks including the digit span forward (DSF) and backward (DSB), the Rey Auditory Verbal Learning Test (RAVLT), and the vocabulary and matrix reasoning subtests of the Wechsler Abbreviated Scale of Intelligence. Participants with ADHD were additionally assessed on ADHD severity, depression symptoms and cardiorespiratory fitness. A series of regressions were run, with sensitivity analyses performed when variables were skewed.
ADHD-control comparisons were significant for DSF, DSB, delayed and recognition memory, with people with ADHD performing less well than the control participants. The result for recognition memory was no longer significant in sensitivity analysis. Memory performance was not associated with greater ADHD or depression symptoms severity. IQ was positively associated with all memory variables except DSF. Cardiorespiratory fitness was negatively associated with the majority of RAVLT variables.
Individuals with ADHD showed difficulties with working memory, short-term memory and delayed memory, as well as a potential difficulty with recognition memory, despite preserved initial learning.
We document the individual willingness to act against climate change and study the role of social norms in a large sample of US adults. Individual beliefs about social norms positively predict pro-climate donations, comparable in strength to universal moral values and economic preferences such as patience and reciprocity. However, we document systematic misperceptions of social norms. Respondents vastly underestimate the prevalence of climate-friendly behaviors and norms. Correcting these misperceptions in an experiment causally raises individual willingness to act against climate change as well as individual support for climate policies. The effects are strongest for individuals who are skeptical about the existence and threat of global warming.
The beetle genus Pharaxonotha Reitter (Coleoptera: Erotylidae: Pharaxonothinae) is found in the cones of cycad genera in the New World, including species of Ceratozamia Brongn., Dioon Lindl., Microcycas (Miq.) A.DC and Zamia L. Its presence and diversity are analyzed for the 17 species of Zamia known to occur in Panama. Nine species are recognized, and five new species are described: Pharaxonotha clarkorum Pakaluk, P. confusa Pakaluk, P. fortunensis Tang, Skelley and Taylor new species, P. holzmani Tang, Skelley and Taylor new species, P. kirschii Reitter, P. manicatae Tang, Skelley and Taylor new species, P. panamensis Tang, Skelley and Taylor new species, P. pseudoparasitica Tang, Skelley and Taylor new species, and P. taylori Skelley and Tang. A key to species of Pharaxonotha in Panama is presented.
ZooBank registration. urn:lsid:zoobank.org:pub:C054B0D4-FD00-4AE7-BBA7-C75A12368561
An overview of the genus Psephenops Grouvelle (Coleoptera: Psephenidae: Psepheninae) is provided with geographic distributions of the species. The taxonomic history of Psephenops smithi Grouvelle, the type species from Grenada and St. Vincent, and junior synonym Xexanchorinus latus Grouvelle from Grenada, is discussed, and lectotypes and paralectotypes are designated for both. Photographs of the type series and a non-type specimen with illustrated male genitalia, along with new distributional information for the species, are provided. The male, female, and associated larva of Psephenops trini Barr and Shepard, new species, are described and illustrated, as is the habitat of this species in Trinidad and Tobago. The Peruvian species Psephenus robacki Spangler is transferred from Psephenus Haldeman to Psephenops as Psephenops robacki (Spangler) new combination. Photographs of the female holotype are included, and possible new distributional records from Peru are reported.
ZooBank registration. urn:lsid:zoobank.org:pub:5C9ECB63-6A77-4FF6-8391-BF0F77BE5674
Pseudococcus longispinus (Targioni-Tozzetti) (Hemiptera: Pseudococcidae) is a widely-distributed pest that feeds on many economically important hosts, particularly tropical fruits and ornamentals. The potential distribution of this mealybug pest in South Korea remains a primary concern because of its high incidence of interceptions screened during inspection. Hence, this species prompted a modelling effort to assess its potential risk of introduction. Potential risk maps were developed for this pest with a CLIMEX model based on occurrence records under environmental data. The potential distribution of these pests in South Korea in the 2020s, 2050s and 2090s was projected based on the RCP 8.5 climate change scenario. Results showed that P. longispinus has little potential for invasion in the outdoor environment of South Korea due to high cold stress in the 2020s. However, some locations in Jejudo were predicted to be marginally suitable under future climate factors. In that respect, the results of this model prediction could be used to prepare a risk-based surveying program that improves the probability of detecting early P. longispinus populations.
ZooBank registration. urn:lsid:zoobank.org:pub:9E0CBFE6-E1AA-4B55-9E58-70B170E0FBD8
A new species, Chlorocoris charluzae Thomas (Hemiptera: Heteroptera: Pentatomidae), is described from Panama. Eludocoris grandis Thomas is reported from Panama for the first time. The distribution of Chlorocoris rufispinus Dallas to include Panama is confirmed. Arawacoris Thomas, described as a subgenus of Chlorocoris Spinola, is elevated to full genus.
ZooBank registration. urn:lsid:zoobank.org:pub:F4E45B6C-5BD8-4B3E-B599-3BB61855B392
Pears, Pyrus pyrifolia (Burm.f.) Nak. (Rosaceae) are one of the most widely grown fruit trees in South Korea. Approximately 11% of the total pear production in 2022 was exported to countries such as the US and Vietnam. Exported pears must be free of pest species that are considered of quarantine importance by the importing countries. Herein, a list of scale insects (Hemiptera: Coccomorpha) associated with pear trees is updated. Additionally, Spilococcus pacificus (Borchsenius) is added to the list of mealybugs affecting pears in South Korea and is briefly diagnosed based on non-type specimens and illustrated using photographs. Information on its distribution and plant hosts are also provided.
ZooBank registration. urn:lsid:zoobank.org:pub:48A93063-EB78-402F-82CE-168540C90FE2
Highlights
• High resolution profile of C. pipiens' sugar diet has been obtained using UHPLC-MS.
• Artificial feeding using ornamental plants provides similar sugar profiles as observed in field collected mosquitoes.
• Metabolomic profiling found secondary metabolites and pollutants of anthropogenic use.
Abstract: Culex pipiens (Linnaeus, 1758) mosquitoes search plant sources of sugars to cope with the energetic demand of various physiological processes. The crop as part of the digestive system is devoted to the storage of sugar-based meal obtained from various nectars sources. The profiling of sugars and metabolites in the Culex pipiens’ crop is scarce, and only few studies used Liquid Chromatography – Mass Spectrometry (LC-MS), which provides broad detection for biomonitoring environmental substances and even contaminants in the sugar diet of mosquitoes populations.
Therefore, sugar and metabolite profiling were performed on crops obtained from mosquitoes exposed to plant nectar under laboratory or natural conditions by Ultra High-Performance LC-MS (UHPLC-MS). This method allowed us a precise quantitative and qualitative identification of sugar diet and associated environmental compounds in the crop of the mosquito C. pipiens. Under laboratory condition, mosquitoes were allowed to feed on either glucose solution, commercially-available flowers or field collected flowers. In addition, we collected mosquitoes from the field to compare those crop metabolomes with metabolome patterns occurring after nectar feeding in the lab.
The sugar quantities and quality obtained from the crops of mosquitoes collected in the field were similar to those crops obtained from mosquitoes that fed on commercially-available flowers and from field collected flowers with a limit of detection of 10 μg/L for sucrose, glucose and sucrose. Next to sugar compounds, we identified 2 types of amino acids, 12 natural products, and 9 pesticides.
Next to the diversity of sugar compounds, we could confirm that secondary metabolites and environmental pollutants are typically up taken from floral nectar sources by C. pipiens. The in-depth knowledge on mosquito–plant interactions may inspire the development and further optimization of mosquito trap systems and arboviral surveillance systems.
The subgenus Indonthophagus Kabakov, 2006 of Onthophagus Latreille, 1802 (Coleoptera: Scarabaeidae: Scarabaeinae: Onthophagini) is reviewed. A morphological definition of it is provided. A diagnosis, based both on external and internal characters, of the seven species deemed to belong to the group according to literature, is supplied. As a result, Onthophagus spinifex (Fabricius, 1781), previously placed with some uncertainty in the subgenus, is definitively excluded. A key to Indonthophagus species is also provided, as well as images of male, aedeagus and endophallus for each species. New country records of Onthophagus turbatus Walker, 1858 for Pakistan, Nepal and Bhutan are given.
ZooBank registration. urn:lsid:zoobank.org:pub:9D0CE9F2-35CF-449D-8984-1B4C722762F7
Members of the genus Centris Fabricius (Hymenoptera: Apoidea: Anthophila) constitute a significant component of the Neotropical (including insular) bee fauna, exhibiting high species richness, a moderate to large body size, and extensive interactions with various important plant groups. Females of most species possess specialized morphology adapted for collecting oils from flowers. This study documents the presence of the genus in Cuba, recognizing six species: C. aethiops Cresson, C. cornuta Cresson, C. fulviventris Cresson, C. poecila Lepeletier, C. taina Genaro and Breto new species, and C. tarsata F. Smith. Detailed information is provided for each species, encompassing a diagnosis, natural history, floral associations, seasonal occurrence, and distribution. Centris taina new species is described from Cuba, based on both sexes, which were previously misidentified as C. versicolor (Fabr.) for females and C. fasciatus F. Smith for males due to sexual dimorphism. Centris tarsata is reported as a new national record for Cuba, possibly introduced by humans from South America and now established and widely distributed across the entire island. A key to differentiate the Cuban species of Centris is presented.
ZooBank registration. urn:lsid:zoobank.org:pub:257916DF-2129-4694-876C-49C858046BF6
The two-particle momentum correlation functions between charm mesons (D∗± and D±) and charged light-flavor mesons (π± and K±) in all charge-combinations are measured for the first time by the ALICE Collaboration in high-multiplicity proton-proton collisions at a center-of-mass energy of s√=13 TeV. For DK and D∗K pairs, the experimental results are in agreement with theoretical predictions of the residual strong interaction based on quantum chromodynamics calculations on the lattice and chiral effective field theory. In the case of Dπ and D∗π pairs, tension between the calculations including strong interactions and the measurement is observed. For all particle pairs, the data can be adequately described by Coulomb interaction only, indicating a shallow interaction between charm and light-flavor mesons. Finally, the scattering lengths governing the residual strong interaction of the Dπ and D∗π systems are determined by fitting the experimental correlation functions with a model that employs a Gaussian potential. The extracted values are small and compatible with zero.
U.S. port of entry interception data revealed that Frankliniella Karny (Thysanoptera: Thripidae) was the most frequently intercepted genus of Thripidae. No published identification resource for intercepted Frankliniella is available to USDA port of entry entomology identifiers. A morphological review of intercepted species was conducted. A dichotomous key for the identification of intercepted slide mounted adult females was created. Morphological diagnosis, description of each species with their geographic region(s) of origin and frequency of interception is provided.
ZooBank registration. urn:lsid:zoobank.org:pub:403B362E-9A7F-4385-A0F1-9DB87FE09AD2
Here, we introduce racoon_clip, a sustainable and fully automated pipeline for the complete processing of iCLIP and eCLIP data to extract RNA binding signal at single-nucleotide resolution. racoon_clip is easy to install and execute, with multiple pre-settings and fully customizable parameters, and outputs a conclusive summary report with visualizations and statistics for all analysis steps.
We prove that the projectivized strata of differentials are not contained in pointed Brill-Noether divisors, with only a few exceptions. For a generic element in a stratum of differentials, we show that many of the associated pointed Brill-Noether loci are of expected dimension. We use our results to study the Auel-Haburcak Conjecture: We obtain new non-containments between maximal Brill-Noether loci in Mg. Our results regarding quadratic differentials imply that the quadratic strata in genus 6 are uniruled.
For genus g=r(r+1)2+1, we prove that via the forgetful map, the universal Prym-Brill-Noether locus Rrg has a unique irreducible component dominating the moduli space Rg of Prym curves.
Can prediction error explain predictability effects on the N1 during picture-word verification?
(2024)
Do early effects of predictability in visual word recognition reflect prediction error? Electrophysiological research investigating word processing has demonstrated predictability effects in the N1, or first negative component of the event-related potential (ERP). However, findings regarding the magnitude of effects and potential interactions of predictability with lexical variables have been inconsistent. Moreover, past studies have typically used categorical designs with relatively small samples and relied on by-participant analyses. Nevertheless, reports have generally shown that predicted words elicit less negative-going (i.e., lower amplitude) N1s, a pattern consistent with a simple predictive coding account. In our preregistered study, we tested this account via the interaction between prediction magnitude and certainty. A picture-word verification paradigm was implemented in which pictures were followed by tightly matched picture-congruent or picture-incongruent written nouns. The predictability of target (picture-congruent) nouns was manipulated continuously based on norms of association between a picture and its name. ERPs from 68 participants revealed a pattern of effects opposite to that expected under a simple predictive coding framework.
The hippocampal-dependent memory system and striatal-dependent memory system modulate reinforcement learning depending on feedback timing in adults, but their contributions during development remain unclear. In a 2-year longitudinal study, 6-to-7-year-old children performed a reinforcement learning task in which they received feedback immediately or with a short delay following their response. Children’s learning was found to be sensitive to feedback timing modulations in their reaction time and inverse temperature parameter, which quantifies value-guided decision-making. They showed longitudinal improvements towards more optimal value-based learning, and their hippocampal volume showed protracted maturation. Better delayed model-derived learning covaried with larger hippocampal volume longitudinally, in line with the adult literature. In contrast, a larger striatal volume in children was associated with both better immediate and delayed model-derived learning longitudinally. These findings show, for the first time, an early hippocampal contribution to the dynamic development of reinforcement learning in middle childhood, with neurally less differentiated and more cooperative memory systems than in adults.
Isothermal titration calorimetry (ITC) is a widely used technique for the characterization of protein-protein and protein-ligand interactions. It provides information on the stoichiometry, affinity, and the thermodynamic driving forces of interactions. This chapter exemplifies the use of ITC to investigate interactions between human autophagy modifiers (LC3/GABARAP proteins) and their interaction partners, the LIR motif containing sequences. The purpose of this report is to present a detailed protocol for the production of LC3/GABARAP-interacting LIR peptides using E. coli expression systems. In addition, we outline the design of ITC experiments using the LC3/GABARAP:peptide interactions as an example. Comprehensive troubleshooting notes are provided to facilitate the adaptation of these protocols to different ligand-receptor systems. The methodology outlined for studying protein-ligand interactions will help to avoid common errors and misinterpretations of experimental results.
Looking beyond ESG preferences: The role of sustainable finance literacy in sustainable investing
(2024)
We assess how sustainable finance literacy affects people’s sustainable investment behavior, using a pre-registered experiment. We find that an increase in sustainable finance literacy leads to a 4 to 5% increase in the probability of investing sustainably. This effect is moderated by sustainability preferences. In the absence of moderate sustainability preferences, any additional increase in sustainable finance literacy is at minimum irrelevant, and we find some evidence that it might even reduce sustainable investments. Our findings underscore the role of knowledge in shaping sustainable investment decisions, highlighting the importance of factors beyond sustainability preferences.
The lipid content of skin plays a determinant role in its barrier function with a particularly important role attributed to linoleic acid and its derivatives. Here we explored the consequences of interfering with the soluble epoxide hydrolase (sEH) on skin homeostasis. sEH; which converts fatty acid epoxides generated by cytochrome P450 enzymes to their corresponding diols, was largely restricted to the epidermis which was enriched in sEH-generated diols. Global deletion of the sEH increased levels of epoxides, including the linoleic acid-derived epoxide; 12,13-epoxyoctadecenoic acid (12,13-EpOME), and increased basal keratinocyte proliferation. sEH deletion (sEH-/- mice) resulted in thicker differentiated spinous and corneocyte layers compared to wild-type mice, a hyperkeratosis phenotype that was reproduced in wild-type mice treated with a sEH inhibitor. sEH deletion made the skin sensitive to inflammation and sEH-/- mice developed thicker imiquimod-induced psoriasis plaques than the control group and were more prone to inflammation triggered by mechanical stress with pronounced infiltration and activation of neutrophils as well as vascular leak and increased 12,13-EpOME and leukotriene (LT) B4 levels. Topical treatment of LTB4 antagonist after stripping successfully inhibited inflammation and neutrophil infiltration both in wild type and sEH-/- skin. While 12,13-EpoME had no effect on the trans-endothelial migration of neutrophils, like LTB4, it effectively induced neutrophil adhesion and activation. These observations indicate that while the increased accumulation of neutrophils in sEH-deficient skin could be attributed to the increase in LTB4 levels, both 12,13-EpOME and LTB4 contribute to neutrophil activation. Our observations identify a protective role of the sEH in the skin and should be taken into account when designing future clinical trials with sEH inhibitors.
Microbial rhodopsins are omnipresent on Earth, however the vast majority of them remain uncharacterized. Here we describe a new rhodopsin clade from cold-adapted organisms and cold environments, such as glaciers, denoted as CryoRhodopsins (CryoRs). Our data suggest that CryoRs have photosensory activity. A distinguishing feature of the clade is the presence of a buried arginine residue close to the cytoplasmic face of its members. Combining single-particle cryo-electron microscopy and X-ray crystallography with the rhodopsin activation by light, we demonstrate that the arginine stabilizes a strongly blue-shifted intermediate of an extremely slow CryoRhodopsin photocycle. Together with extensive spectroscopic characterization, our investigations on CryoR1 and CryoR2 proteins reveal mechanisms of photoswitching in the newly identified clade and demonstrate principles of the adaptation of these rhodopsins to low temperatures.
Die Bibliographie nennt alle in der Deutschen Nationalbibliothek vorhandenen Bücher Grete Fischers. Die Titel wurden mit Ausnahme der drei 1945/46 in Glasgow erschienenen Bücher autoptisch überprüft. Als Verlagslektorin hat sie durch mehrere Jahrzehnte an deutschen und englischen Übersetzungen mitgewirkt, die sich bisher jedoch bibliographisch nicht nachweisen ließen.
This paper studies whether Eurosystem collateral eligibility played a role in the portfolio choices of euro area asset managers during the “dash-for-cash” episode of 2020. We find that asset managers reduced their allocation to ECB-eligible corporate bonds, selling them in order to finance redemptions, while simultaneously increasing their cash holdings. These findings add nuance to previous studies of liquidity strains and price dislocations in the corporate bond market during the onset of the Covid-19 pandemic, indicating a greater willingness of dealers to increase their inventories of corporate bonds pledgeable with the ECB. Analysing the price impact of these portfolio choices, we also find evidence pointing to price pressure for both ECB-eligible and ineligible corporate bonds. Bonds that were held to a larger extent by investment funds in our sample experienced higher price pressure, although the impact was lower for ECB-eligible bonds. We also discuss broader implications for the related policy debate about how central banks could mitigate similar types of liquidity shocks.
The two-particle momentum correlation functions between charm mesons (D∗± and D±) and charged light-flavor mesons (π± and K±) in all charge-combinations are measured for the first time by the ALICE Collaboration in high-multiplicity proton–proton collisions at a center-of-mass energy of √s = 13 TeV. For DK and D∗K pairs, the experimental results are in agreement with theoretical predictions of the residual strong interaction based on quantum chromodynamics calculations on the lattice and chiral effective field theory. In the case of Dπ and D∗π pairs, tension between the calculations including strong interactions and the measurement is observed. For all particle pairs, the data can be adequately described by Coulomb interaction only, indicating a shallow interaction between charm and light-flavor mesons. Finally, the scattering lengths governing the residual strong interaction of the Dπ and D∗π systems are determined by fitting the experimental correlation functions with a model that employs a Gaussian potential. The extracted values are small and compatible with zero.
Measurement of beauty-quark production in pp collisions at √s = 13 TeV via non-prompt D mesons
(2024)
The pT-differential production cross sections of non-prompt D0, D+, and D+s mesons originating from beauty-hadron decays are measured in proton−proton collisions at a centre-of-mass energy s√ of 13 TeV. The measurements are performed at midrapidity, |y|<0.5, with the data sample collected by ALICE from 2016 to 2018. The results are in agreement with predictions from several perturbative QCD calculations. The fragmentation fraction of beauty quarks to strange mesons divided by the one to non-strange mesons, fs/(fu+fd), is found to be 0.114±0.016 (stat.)±0.006 (syst.)±0.003 (BR)±0.003 (extrap.). This value is compatible with previous measurements at lower centre-of-mass energies and in different collision systems in agreement with the assumption of universality of fragmentation functions. In addition, the dependence of the non-prompt D meson production on the centre-of-mass energy is investigated by comparing the results obtained at s√=5.02 and 13 TeV, showing a hardening of the non-prompt D-meson pT-differential production cross section at higher s√. Finally, the bb¯¯¯ production cross section per unit of rapidity at midrapidity is calculated from the non-prompt D0, D+, D+s, and Λ+c hadron measurements, obtaining dσ/dy=75.2±3.2 (stat.)±5.2 (syst.)+12.3−3.2 (extrap.) μb.
Measurements of the pT-dependent flow vector fluctuations in Pb-Pb collisions at sNN−−−√=5.02 TeV using azimuthal correlations with the ALICE experiment at the LHC are presented. A four-particle correlation approach [1] is used to quantify the effects of flow angle and magnitude fluctuations separately. This paper extends previous studies to additional centrality intervals and provides measurements of the pT-dependent flow vector fluctuations at sNN−−−√=5.02 TeV with two-particle correlations. Significant pT-dependent fluctuations of the V⃗ 2 flow vector in Pb-Pb collisions are found across different centrality ranges, with the largest fluctuations of up to ∼15% being present in the 5% most central collisions. In parallel, no evidence of significant pT-dependent fluctuations of V⃗ 3 or V⃗ 4 is found. Additionally, evidence of flow angle and magnitude fluctuations is observed with more than 5σ significance in central collisions. These observations in Pb-Pb collisions indicate where the classical picture of hydrodynamic modeling with a common symmetry plane breaks down. This has implications for hard probes at high pT, which might be biased by pT-dependent flow angle fluctuations of at least 23% in central collisions. Given the presented results, existing theoretical models should be re-examined to improve our understanding of initial conditions, quark--gluon plasma (QGP) properties, and the dynamic evolution of the created system.
The intense photon fluxes from relativistic nuclei provide an opportunity to study photonuclear interactions in ultraperipheral collisions. The measurement of coherently photoproduced π+π−π+π− final states in ultraperipheral Pb-Pb collisions at sNN−−−√=5.02 TeV is presented for the first time. The cross section, dσ/dy, times the branching ratio (ρ→π+π+π−π−) is found to be 47.8±2.3 (stat.)±7.7 (syst.) mb in the rapidity interval |y|<0.5. The invariant mass distribution is not well described with a single Breit-Wigner resonance. The production of two interfering resonances, ρ(1450) and ρ(1700), provides a good description of the data. The values of the masses (m) and widths (Γ) of the resonances extracted from the fit are m1=1385±14 (stat.)±3 (syst.) MeV/c2, Γ1=431±36 (stat.)±82 (syst.) MeV/c2, m2=1663±13 (stat.)±22 (syst.) MeV/c2 and Γ2=357±31 (stat.)±49 (syst.) MeV/c2, respectively. The measured cross sections times the branching ratios are compared to recent theoretical predictions.