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Medium modification of the shape of small-radius jets in central Pb–Pb collisions at √sNN = 2.76 TeV
(2019)
We present the measurement of a new set of jet shape observables for track-based jets in central Pb-Pb collisions at sNN−−−√=2.76 TeV. The set of jet shapes includes the first radial moment or angularity, g; the momentum dispersion, pTD; and the difference between the leading and sub-leading constituent track transverse momentum, LeSub. These observables provide complementary information on the jet fragmentation and can constrain different aspects of the theoretical description of jet-medium interactions. The jet shapes were measured for a small resolution parameter R=0.2 and were fully corrected to particle level. The observed jet shape modifications indicate that in-medium fragmentation is harder and more collimated than vacuum fragmentation as obtained by PYTHIA calculations, which were validated with the measurements of the jet shapes in proton-proton collisions at s√=7 TeV. The comparison of the measured distributions to templates for quark and gluon-initiated jets indicates that in-medium fragmentation resembles that of quark jets in vacuum. We further argue that the observed modifications are not consistent with a totally coherent energy loss picture where the jet loses energy as a single colour charge, suggesting that the medium resolves the jet structure at the angular scales probed by our measurements (R=0.2). Furthermore, we observe that small-R jets can help to isolate purely energy loss effects from other effects that contribute to the modifications of the jet shower in medium such as the correlated background or medium response.
As its fundamental function, the brain processes and transmits information using populations of interconnected nerve cells alias neurons. The communication between these neurons occurs via discrete electric impulses called spikes. A core challenge in neuroscience has been to quantify how much information about relevant stimuli or signals a neuron transports in its spike sequences, or spike trains. The recently introduced correlation method allows to determine this so-called mutual information in terms of a neuron’s temporal spike correlations under certain stationarity assumptions. Based on the correlation method, I address several open questions regarding neural information encoding in the cortex.
In the first part (chapter 2), I investigate the role of temporal spike correlations for neural information transmission. Temporal correlations in neuronal spike trains diminish independence in the information that is transmitted by the different spikes and hence introduce redundancy to stimulus encoding. However, exact methods to describe how such spike correlations impact information transmission quantitatively have been lacking. Here, I provide a general measure for the information carried by spike trains of neurons with correlated rate modulations only, neglecting other spike correlations, and use it to investigate the effect of rate correlations on encoding redundancy. I derive it analytically by calculating the mutual information between a time correlated, rate-modulating signal and the resulting spikes of Poisson neurons. Whereas this information is determined by spike autocorrelations only, the redundancy in information encoding due to rate correlations depends on both the distribution and the autocorrelation of the rate histogram. I further demonstrate that, at very small signal strengths, the information carried by rate correlated spikes becomes identical to that of independent spikes, in effect measuring the rate modulation depth. In contrast, a vanishing signal correlation time maximizes information transmission but does not generally yield the information of independent spikes.
In the second part (chapter 3), I analyze the information transmission capabilities of two particular schemes of encoding stimuli in the synaptic inputs using integrate-and-fire neuron models. Specifically, I calculate the exact information contained in spike trains about signals which modulate either the mean or the variance of the somatic currents in neurons, as is observed experimentally. I show that the information content about mean modulating signals is generally substantially larger than about variance modulating signals for biological parameters. This result provides evidence, by means of exact calculations of the mutual information, against the potential benefit of variance encoding that had been suggested previously.
Another analysis reveals that higher information transmission is generally associated with a larger proportion of nonlinear signal encoding. Moreover, I show that a combination of signal-dependent mean and variance modulations of the input current can synergistically benefit information transmission through a nonlinear coupling of both channels. On a more general level, I identify what was previously considered an upper bound as the exact, full mutual information. Furthermore, by analyzing the statistics of the spike train Fourier coefficients, I identify the means of the Fourier coefficients as information-carrying features.
Overall, this work contributes answers to central questions of theoretical neuroscience concerning the neural code and neural information transmission. It sheds light on the role of signal-induced temporal correlations for neural coding by providing insight into how signal features shape redundancy and by establishing mathematical links between existing methods and providing new insights into the spike train statistics in stationary situations. Moreover, I determine what fraction of the mutual information is linearly decodable for two specific signal encoding schemes.
Mechanism of the electroneutral sodium/proton antiporter PaNhaP from transition-path shooting
(2019)
Na+/H+ antiporters exchange sodium ions and protons on opposite sides of lipid membranes. The electroneutral Na+/H+ antiporter NhaP from archaea Pyrococcus abyssi (PaNhaP) is a functional homolog of the human Na+/H+ exchanger NHE1, which is an important drug target. Here we resolve the Na+ and H+ transport cycle of PaNhaP by transition-path sampling. The resulting molecular dynamics trajectories of repeated ion transport events proceed without bias force, and overcome the enormous time-scale gap between seconds-scale ion exchange and microseconds simulations. The simulations reveal a hydrophobic gate to the extracellular side that opens and closes in response to the transporter domain motion. Weakening the gate by mutagenesis makes the transporter faster, suggesting that the gate balances competing demands of fidelity and efficiency. Transition-path sampling and a committor-based reaction coordinate optimization identify the essential motions and interactions that realize conformational alternation between the two access states in transporter function.
We present the first measurements of femtoscopic correlations between the K0 S and K± particles in pp collisions at √s = 7 TeV measured by the ALICE experiment. The observed femtoscopic correlations are consistent with final-state interactions proceeding solely via the a0(980) resonance. The extracted kaon source radius and correlation strength parameters for K0 SK− are found to be equal within the experimental uncertainties to those for K0 SK+. Results of the present study are compared with those from identical-kaon femtoscopic studies also performed with pp collisions at √s = 7 TeV by ALICE andwith a K0 SK± measurement in Pb–Pb collisions at √sNN = 2.76 TeV. Combined with the Pb–Pb results, our pp analysis is found to be compatible with th e interpretation of the a0(980) having a tetraquark structure instead of that of a diquark.
We present the first measurements of femtoscopic correlations between the K0S and K± particles in pp collisions at s√=7 TeV measured by the ALICE experiment. The observed femtoscopic correlations are consistent with final-state interactions proceeding solely via the a0(980) resonance. The extracted kaon source radius and correlation strength parameters for K0SK− are found to be equal within the experimental uncertainties to those for K0SK+. Results of the present study are compared with those from identical-kaon femtoscopic studies also performed with pp collisions at s√=7 TeV by ALICE and with a K0SK± measurement in Pb-Pb collisions at sNN−−−√=2.76 TeV. Combined with the Pb-Pb results, our pp analysis is found to be compatible with the interpretation of the a0(980) having a tetraquark structure instead of that of a diquark.
Measurements of the π±, K±, and proton double differential yields emitted from the surface of the 90-cm-long carbon target (T2K replica) were performed for the incoming 31 GeV/c protons with the NA61/SHINE spectrometer at the CERN SPS using data collected during 2010 run. The double differential π± yields were measured with increased precision compared to the previously published NA61/SHINE results, while the K± and proton yields were obtained for the first time. A strategy for dealing with the dependence of the results on the incoming proton beam profile is proposed. The purpose of these measurements is to reduce significantly the (anti)neutrino flux uncertainty in the T2K long-baseline neutrino experiment by constraining the production of (anti)neutrino ancestors coming from the T2K target.
Using 𝑒+𝑒−→Λ+𝑐¯Λ−𝑐 production from a 567 pb−1 data sample collected by BESIII at 4.6 GeV, a full angular analysis is carried out simultaneously on the four decay modes of Λ+𝑐→𝑝𝐾0𝑆, Λ𝜋+, Σ+𝜋0, and Σ0𝜋+. For the first time, the Λ+𝑐 transverse polarization is studied in unpolarized 𝑒+𝑒− collisions, where a nonzero effect is observed with a statistical significance of 2.1𝜎. The decay asymmetry parameters of the Λ+𝑐 weak hadronic decays into 𝑝𝐾0𝑆, Λ𝜋+, Σ+𝜋0 and Σ0𝜋+ are measured to be 0.18±0.43(stat)±0.14(syst), −0.80±0.11(stat)±0.02(syst), −0.57±0.10(stat)±0.07(syst), and −0.73±0.17(stat)±0.07(syst), respectively. In comparison with previous results, the measurements for the Λ𝜋+ and Σ+𝜋0 modes are consistent but with improved precision, while the parameters for the 𝑝𝐾0𝑆 and Σ0𝜋+ modes are measured for the first time.
GSI High Energy Beam Transfer lines (HEST) link the SIS18 synchrotron with two storage rings (Experimental Storage Ring and Cryring) and six experimental caves. The recent upgrades to HEST beam instrumentation enables precise measurements of beam properties along the lines and allow for faster and more precise beams setup on targets. Preliminary results of some of the measurements performed during runs in 2018 and 2019 are presented here. The focus is on response matrix measurements and quadrupole scans performed on HADES beam line. The errors and future improvements are discussed.
Transverse-momentum (pT) differential yields of electrons from semileptonic heavy-flavour hadron decays have been measured in the most central (0-10%) and in semi-central (20-40%) Pb-Pb collisions at sNN−−−√=2.76 TeV. The corresponding production cross section in pp collisions has been measured at the same energy with substantially reduced systematic uncertainties with respect to previously published results. The modification of the yield in Pb-Pb collisions with respect to the expectation from an incoherent superposition of nucleon-nucleon collisions is quantified at mid-rapidity (|y| < 0.8) in the pT interval 0.5-3 GeV/c via the nuclear modification factor, RAA. This paper extends the pT reach of the RAA measurement towards significantly lower values with respect to a previous publication. In Pb-Pb collisions the pT-differential measurements of yields at low pT are essential to investigate the scaling of heavy-flavour production with the number of binary nucleon-nucleon collisions. Heavy-quark hadronization, a collective expansion and even initial-state effects, such as the nuclear modification of the Parton Distribution Functions, are also expected to have a significant effect on the measured distribution.
This article reports measurements of the pT-differential inclusive jet cross-section in pp collisions at s√ = 5.02 TeV and the pT-differential inclusive jet yield in Pb-Pb 0-10% central collisions at sNN−−−√ = 5.02 TeV. Jets were reconstructed at mid-rapidity with the ALICE tracking detectors and electromagnetic calorimeter using the anti-kT algorithm. For pp collisions, we report jet cross-sections for jet resolution parameters R=0.1−0.6 over the range 20<pT,jet<140 GeV/c, as well as the jet cross-section ratios of different R, and comparisons to two next-to-leading-order (NLO)-based theoretical predictions. For Pb-Pb collisions, we report the R=0.2 and R=0.4 jet spectra for 40<pT,jet<140 GeV/c and 60<pT,jet<140 GeV/c, respectively. The scaled ratio of jet yields observed in Pb-Pb to pp collisions, RAA, is constructed, and exhibits strong jet quenching and a clear pT-dependence for R=0.2. No significant R-dependence of the jet RAA is observed within the uncertainties of the measurement. These results are compared to several theoretical predictions.