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Nach der Wiedervereinigung der beiden deutschenStaaten im Jahr 1990 wurde in den neuen Bundesländern der weitgehend verstaatlichte Grund undBoden in Privateigentum zurücküberführt. Da in derDDR eine Wiedergutmachung nationalsozialistischenUnrechts weitgehend ausgeblieben war, wurde dieRestitutionsregelung auf die Eigentumsentziehungenbis 1933 ausgedehnt.Die wenig erforschte «Arisierung» des Grundeigentums während des Nationalsozialismus gewann damitan erneuter Aktualität. Die «Arisierung» als Teilder nationalsozialistischen Judenverfolgung bedeuteteeine vollständige Verdrängung der Juden aus der Wirtschaft und damit auch aus dem Immobilienbereich.Das Ergebnis der «Arisierung» war «eine der grösstenBesitzumschichtungen der Neuzeit».Ziel des Artikels ist es, einen Überblick über die rechtlichen Regelungen und den Ablauf der «Arisierung»des Grundeigentums zu geben und mit einer Fallstudiediesen Prozess für ein konkretes Quartier im OstteilBerlins darzustellen.
The constitution and regulation of effector repertoires shape host–microbe interactions. Ustilago maydis and Sporisorium reilianum are two closely related smut fungi, which both infect maize but cause distinct disease symptoms. Understanding how effector orthologs are regulated in these two pathogens can therefore provide insights into the evolution of different infection strategies. We tracked the infection progress of U. maydis and S. reilianum in maize leaves and used two distinct infection stages for cross-species RNA-sequencing analyses. We identified 207 of 335 one-to-one effector orthologs as differentially regulated during host colonization, which might reflect the distinct disease development strategies. Using CRISPR-Cas9-mediated gene conversion, we identified two differentially expressed effector orthologs with conserved function between two pathogens. Thus, differential expression of functionally conserved genes might contribute to species-specific adaptation and symptom development. Interestingly, another differentially expressed orthogroup (UMAG_05318/Sr10075) showed divergent protein function, providing a possible case for neofunctionalization. Collectively, we demonstrated that the diversification of effector genes in related pathogens can be caused both by alteration on the transcriptional level and through functional diversification of the encoded effector proteins.
The four novels of Cătălin Dorian Florescu (Wunderzeit, Der kurze Weg nach Hause, Der blinde Masseur, Zaira) analysed here are interpreted in relation to the chronotope, a term developed by Michail Bachtin meaning the connectedness of time and space in narrative. Space knows two opposite dimensions in Florescu’s works: the West (Switzerland, USA) and the East (Romania). The Romanian space is represented by three different images corresponding to three different periods: Romania between the two world wars, during the communist period and after 1989. The main characters are Romanians who leave their country of origin during the communist period, hoping that they will find a better life in the West. After the revolt in 1989, the characters return to the space of their childhood, where they could find themselves and happiness once again. There are analyzed different aspects of the aesthetic space Romania: exotic space, space of discovery of oneself, spiritual space of traditions, but also space of disappointment and of perils. Space is in close connection with movement, the movement of the protagonists from one dimension to another, which is also the basis of the plot.
This paper explores the context and reasons for the extensive translation of legal texts from German into Romanian in Bukovina during the Habsburg period (1775–1918) and immediately following the unification with the Romanian Kingdom. The Austrian civil code from 1811 was translated in the three important periods of translation, corresponding to the major administrative changes in the province. The paper analyses the different translations and their impact on the Romanian legislation, legal terminology and juridical style.
Der Große Eichenbock (Cerambyx cerdo L.) wird in der früheren forstwirtschaftlichen Literatur wegen der durch ihn verursachten großen Holzentwertung als erheblicher Schädling bezeichnet (z. B. Eschrich 1923 und Rudnew 1936). Heute ist er nach der Roten Liste der gefährdeten Tiere und Pflanzen der Bundesrepublik Deutschland (1984) eine vom Aussterben bedrohte Tierart. Aktuelle Angaben zur Bestandssituation des Großen Eichenbocks für das Gebiet der ehemaligen DDR existieren nur von Neumann und Kühnel (1980) und von Neumann (1985). Nach diesen Angaben stellt das Mittelelbegebiet einen der wenigen Verbreitungsschwerpunkte im Osten Deutschlands dar.
Ein Lachs in der Mulde
(2005)
Am 11.12.2004 fing ein Angler aus Dessau in der Mulde unterhalb des Stadtwehres Dessau einen Lachs (Salmo salar). Bei diesem 70 cm langen Fisch handelt es sich um ein laichreifes Tier, das sich offensichtlich in die Mulde verirrt hatte und am Dessauer Wehr am Weiteraufstieg gehindert wurde. Es ist der erste Nachweis dieser Fischart in der unteren Mulde, nachdem sie in der zweiten Hälfte des 19. Jahrhunderts durch den Bau großer massiver Wehranlagen in der gesamten Mulde ausstarb.
Bei einer Fischarten-Erfassung an der Elbe zwischen Arneburg und Sandau fanden Dipl.-Biol. J. Huth, G. Belkner und der Verfasser am 14.10.2004 in der Nähe des rechten Ufers zwischen Strom-km 409 und 410 an einem etwa 10 cm langen Barsch (Perca fluviatilis) ein etwa 2 cm langes Krebstier, das wie eine kleine Garnele aussah. Die Determination dieses Fundtieres durch Frau Dipl.-Biol. U. Michels ergab Atyaephyra desmaresti, die einzige in Deutschland vorkommende Süßwassergarnele.
Da in Sachsen-Anhalt alle vorkommenden Branchiopodenarten (= Blatt- oder Kiemenfüßer) in ihrer Existenz gefährdet sind (Neumann & Heinze 2004), erscheint eine verstärkte Aufmerksamkeit gegenüber ihren Vorkommen angebracht. Auch die beeindruckende Tatsache, dass diese Tiere in fast unveränderter Form bereits vor rund 500 Millionen Jahren auf der Erde lebten, die ihnen auch den Namen „Urzeitkrebse“ eingebracht hat, rechtfertigt diese gebotene Aufmerksamkeit. Da auch Engelmann & Hahn (2004) im Ergebnis ihrer umfangreichen Recherche über das Vorkommen der Branchiopodenarten in Deutschland „ermutigen, bekannte und potentielle Vorkommen … publik und behördenzugänglich zu machen“, soll hier das Ergebnis einer Suche nach dem Blattfußkrebs Lepidurus apus in der Umgebung von Lutherstadt Wittenberg dargelegt werden.
Das 358,75 ha große Naturschutzgebiet „Alte Elbe bei Bösewig“ liegt etwa 20 km südöstlich von Lutherstadt Wittenberg zwischen dem Hochwasserdeich und der Elbe, unmittelbar östlich der Ortschaft Bösewig. Vom Deich bei Bösewig bietet sich ein Blick auf den inmitten von Überflutungsgrünland gelegenen Mäanderbogen der Elbe, der mit seinem Umland aus überwiegend avifaunistischen Gründen zum Naturschutzgebiet erklärt wurde (LAU 1997). Das Gebiet dient als "Mauser-, Übersommerungs-, Rast- und Überwinterungsgebiet" zahlreicher Vogelarten, zu denen auch der Kranich (Grus grus) zählt.
Am 25.06.2004 fand R. Scharapenko in einer Wasserpfütze in der Teucheler Heide nördlich von Wittenberg „Kiemenfüße“. Der Verfasser konnte am 26.06.04 vor Ort in einer nur ca. 50 x 50 cm großen und ca. 5-10 cm tiefen, lehmigen Pfütze auf einem Weg zwischen zahlreichen Kreuzkrötenlarven (Bufo calamita) ebenfalls viele Kiemenfüße erkennen. Sie erreichten eine Länge von ca. 20 mm. Unter dem Binokular waren die an der Basis durch eine Naht getrennten Frontalanhänge gut zu erkennen, so dass die Artdiagnose Branchipus schaefferi Fischer, 1834, gesichert ist. Somit handelt es sich um den ersten Nachweis dieses Kiemenfußkrebses (Anostraca) für den Kreis Wittenberg.
Bei einer im Auftrag des Wasser- und Schiffahrtsamtes Dresden durchgeführten Befischung der Eibe bei Coswig (Sachsen-Anhalt) im Biosphärenreservat "Mittlere Eibe" mit einem Elektrofischfanggerät zur Arterfassung der Fischfauna konnte am 19.10.1999 mit dem Weißflossengründling (Gobio albipinnatus Lukasch, 7933) eine für Sachsen-Anhalt neue Fischart nachgewiesen werden. Angeregt durch den Hinweis von GAUMERT (1998), der in der sächsischen Eibe diese bisher nur aus dem Donau-Einzugsgebiet sowie dem Wolga- und Donbecken bekannte Gründlingsart nachweisen konnte, wurden die bei der oben angeführten Befischung gefangenen 134 Gründlinge besonders aufmerksam gemustert.
Beim herbstlichen Abfischen des Großen Lausiger Teiches im Naturschutzgebiet (NSG) "Lausiger Teiche und Ausreißerteich" (LK Wittenberg) am 28.10.2000 durch Fischer Jörg FLEMMIG fiel dem Verfasser auf dem Sortiertisch ein Kleinfisch auf, den er als Blaubandgründling (Pseudorasbora parva [SCHLEGEL, 1842]) bestimmte. Der etwa 7 cm lange Fisch war grünlich-grau gefärbt, wobei die untere Körperhälfte silbrig schimmmerte und die Schuppen dunkel umrandet waren. In der Körpermitte verlief von den Kiemen bis zur Mitte des Schwanzansatzes ein breiter dunkler Streifen. Der Kopf mit dem leicht oberständigen Maul lief spitz aus.
Der Steinbeißer (Cobitis taenia L.) ist eine Fischart, die in allen deutschen Bundesländern als selten gilt und in den "Roten Listen" als gefährdete Art eingestuft ist. Zurückgeführt wird diese Situation überwiegend auf die Einschränkung des Lebensraumes dieser spezialisierten Fischart, der in der Literatur übereinstimmend als "klare Gewässer mit Sandgrund" angegeben wird.
Dr. Wolfram Jakobs gestorben
(1997)
Nach langer schwerer Krankheit starb am 8. August 1996 im Alter von 60 Jahren der im Naturschutz des Kreises Wittenberg aktive und besonders bei den Herpetologen und Libellenfreunden wohlbekannte Dr. Wolfram Jakobs. Trotz des Wissens um die unheilbare Krankheit kam sein Tod für viele seiner Freunde und Mitstreiter unverhofft, hatte er doch bis zum Ende seinen Lebensmut behalten. Noch zwei Wochen vor seinem Tod bestimmte er, obwohl bettlägerig, die ihm vorgelegten Libellen.
Vorkommen und Verbreitung der Fischarten im südlichen Sachsen-Anhalt und ihre Schutzsituation
(1993)
Die Verbreitung der Wirbeltierarten in Deutschland ist im Wesentlichen bekannt. Nur die Kenntnis über die Fischarten ist nach wie vor sehr lückenhaft, obwohl die Fische seit altersher das Interesse der Menschen fanden. Allerdings war dieses Interesse stark nutzungsorientiert, so dass es fast unbemerkt blieb, dass die wirtschaftlich und angelsportlich uninteressanten Arten - besonders die sogenannten "Kleinfische" - immer seltener wurden. Für das Gebiet der ehemaligen DDR musste Paepke bereits 1981 ca. 70% der nachgewiesenen Arten als verschollen, stark gefährdet oder gefährdet einstufen. Die in der Bundesrepublik Deutschland (Bless; Lelek 1984) und in allen alten Bundesländern erstellten "Roten Listen" (Bless 1989) belegen, dass auch im westlichen Deutschland der gleiche Anteil der autochthonen Fischarten bedroht ist.
Bei einer für den Verein Dübener Heide e.V. im Herbst 2003 durchgeführten Fischartenerfassung mittels Elektrobefischung im Fliethbach zwischen Reinharz und Reuden (Lkrs. Wittenberg) im FFH-Gebiet "Fliethbach-System zwischen Dübener Heide und Elbe" wurden die Auswirkungen der Besiedlung des Gebietes durch den Biber (Castor fiber) auf die Ichthyozönose des Baches sichtbar. Daraus ergibt sich ein Konflikt zwischen mehreren Schutzzielen der FFH-Richtlinie, der auch an anderen kleinen Fließgewässern zumindest visuell erfasst wurde.
Bei einer Fischarten-Erfassung in der Elbe zwischen Arneburg und Sandau (Landkreis Stendal) am 06.07.2005 fingen J. Huth, M. Reuter und der Verfasser am linken Ufer bei Strom-km 410 auf einer flach überströmten Kiesbank im Buhnenfeld drei Nasen (Chondrostoma nasus) von je etwa 15 cm Länge. Die Fischart Nase wird in der Roten Liste Sachsen-Anhalts (Kammerad et al. 2004) in der Gefährdungskategorie 1 geführt. Damit gilt sie hier als vom Aussterben bedroht.
Trotz einer geringen Gewässernetzdichte von 0,4–1,7 km/km2 sind Fließ- und Stillgewässer in der Dübener Heide stellenweise landschaftsprägende Strukturen, die neben ihrer landschaftsvernetzenden Funktion und landschaftsästhetischen Wirkung auch eine hohe ökologische Bedeutung haben. Sowohl die von den Erhebungen der Altmoränenlandschaft in ehemaligen Schmelzwasserabflussrinnen der Elbe oder Mulde zufließenden Fließgewässer als auch die durch Anstau oder Abgrabungen durch Menschenhand geschaffenen Stillgewässer sind entsprechend ihrer Beschaffenheit wichtige Lebensräume für aquatische und amphibische Lebensgemeinschaften.
In der gewässerarmen Landschaft des Roßlau-Wittenberger Vorflämings sind Feldsölle wichtige aquatische Lebensräume. Einige dieser Feldsölle im Raum Rahnsdorf- Klebitz nördlich von Zahna (Lkr. Wittenberg), die nach der Klassifizierung von Klafs et al. (1973) als „Pseudosölle“ ausgebildet sind, wurden 1983 als FND ausgewiesen (RdK WB 1987) und nunmehr als FFH-Gebiet „Klebitz-Rahnsdorfer Feldsölle“ (FFH0234LSA) in das Schutzgebietssystem NATURA 2000 des Landes Sachsen-Anhalt integriert (Haslbeck 2010).
Die Schwarze Elster ist ein anschauliches Beispiel dafür, wie schnell ein biologisch total verödeter Fluss (Erfurt 2007) nach Wegfall ehemals ungehemmter Einleitung von stark verunreinigtem Abwasser wieder zu einem völlig intakten Fließgewässer regeneriert. Bereits 1992 wurden wieder 16, 1994 bereits 23 sowie 1997 und 2002 sogar jeweils 26 Fischarten nachgewiesen (Zuppke 2010). Mit Barbe, Döbel, Hasel, Schmerle, Zope, Rapfen, Gründling, Aland und Quappe kommen auch wieder rheophile Arten vor, also auf Strömung angewiesene Arten, bei denen entweder der gesamte Lebenszyklus oder zumindest große Lebensabschnitte im Fließgewässer verlaufen.
Bei einer Fischarten-Erfassung in der Schwarzen Elster bei Schweinitz (Lkr. Wittenberg) am 13.4.2012 durch H. Zuppke, L. Reichhoff und U. Zuppke konnte durch den Fang einer Zährte (Vimba vimba [Linnaeus, 1758]) eine weitere strömungsliebende Fischart nachgewiesen und zugleich der Erstnachweis dieser Art für diesen Flussabschnitt erbracht werden.
Die im Gewässergrund verborgene Lebensweise des Steinbeißers (Cobitis taenia Linnaeus, 1758) brachte es mit sich, dass die Kenntnis über die Verbreitung dieser Fischart große Lücken aufweist. Bei der Erarbeitung der Roten Liste der Fische und Rundmäuler Sachsen-Anhalts im Jahre 1992 (Zuppke et al. 1992) lagen nur sehr wenige Nachweise des Steinbeißers vor, so dass er damals in die Kategorie 1 „vom Aussterben bedroht“ eingestuft werden musste. Erst durch den Einsatz von Elektrofischfanggeräten verdichteten sich die Hinweise. Bei der Aktualisierung der Roten Liste 2004 (Kammerad et al. 2004) zeigte die nun vorhandene erweiterte Datenlage, dass der Steinbeißer doch nicht so selten ist und eine Rückstufung in die Kategorie 2 „stark gefährdet“ vorgenommen werden konnte. Insgesamt ist der Steinbeißer in Deutschland und darüber hinaus in seinem gesamten europäischen Verbreitungsgebiet, das von den Pyrenäen bis zum Ural mit Ausnahme von Nordskandinavien, Irland, Schottland und dem südlichen Balkan reicht, durch seine Bindung an bestimmtes Bodensubstrat gefährdet, so dass er in den Anhang II der FFH-Richtlinie aufgenommen wurde.
Im soeben erschienenen Handbuch der FFH-Gebiete Sachsen-Anhalts (Jentzsch & Reichhoff 2013) wird für das FFH-Gebiet "Feuchtwiese bei Dobien" (FFH0250LSA) angegeben, dass keine Kenntnisse zur Fauna vorliegen. Daher erscheint es angebracht, über das dortige Vorkommen einer gefährdeten Tagfalterart zu informieren. Herrn Dr. Hünefeld (UNB Wittenberg) gebührt Dank für die Überlassung von Informationen aus unveröffentlichten Berichten der Behörde.
Eines der 193 bereits im Jahre 2000 gemeldeten FFH-Gebiete (Fauna-Flora-Habitat) des Schutzgebietssystems NATURA 2000 des Landes Sachsen- Anhalt ist die „Untere Muldeaue“ (Nr. 129). In ihm kommen mit dem Unterlauf der Mulde der Lebensraumtyp 3260 „Fließgewässer der planaren bis montanen Stufe mit Vegetation des Ranunculion fluitantis“ nach Anhang I der FFH-Richtlinie und neben Säugetier-, Lurch- und Insektenarten auch vier Fischarten nach Anhang II der FFH-Richtlinie vor (NATURA 2000). Diese Landschaft ist gleichzeitig als Naturschutzgebiet und als Bestandteil des Biosphärenreservats Mittlere Elbe und des Landschaftsschutzgebietes Mittlere Elbe und Mittelelbe geschützt.
Das Meerneunauge gehört zur Familie der Petromyzonidae (Neunaugen). Es wird 50 – 80 cm lang, ist graugrün gefärbt mit einer dunklen Marmorierung auf der Oberseite, hat einen langgestreckten, aalähnlichen Körper und eine zweigeteilte Rückenflosse (GEBHARDT & NESS 1997). Seine Mundscheibe ist durch zahlreiche, ringförmige Reihen von Hornzähnchen gekennzeichnet (MUUS & DAHLSTRÖM 1993).
Der publizierte Nachweis von Lepidurus apus (L.) in der Elbtalaue bei Rühstädt (Bulow 1992) gibt Anlass, auf das Vorkommen dieses Blattfußkrebses (Phyllopoda) im Mittelelbegebiet bei Wittenberg hinzuweisen, da diese Art von Heidecke und Neumann (1987) wegen ihres erdgeschichtlichen Alters und ihrer ökologischen Spezialisierung als "Naturschutzobjekt" bezeichnet wird.
Das Flussneunauge (Lampetra fluviatilis Linnaeus, 1758), das im Anhang II der FFH-Richtlinie als Tierart „von gemeinschaftlichem Interesse“ aufgeführt ist, lebt in den Küstenregionen europäischer Meere und wandert als erwachsenes Tier zum Laichen in die einmündenden Flüsse. Daher kommt bzw. kam es in Sachsen-Anhalt nur in der Elbe und größeren Nebenflüssen wie der Havel, Mulde, Saale und Schwarzen Elster vor (Kammerad et al. 1997). Hier war es aber durch die starke Abwasserbelastung und den Bau des Elbewehres in Geesthacht (Niedersachsen) ausgestorben. Erst nach der Verbesserung der Wassergüte und der Errichtung von funktionsfähigen Fischaufstiegsanlagen in Geesthacht konnte es wieder in der Elbe aufsteigen. Am 1.5.2002 gelang der erste Nachweis für den erfolgreichen Aufstieg dieser Art in den Bereich der Mittelelbe durch den Fang von 34 Flussneunaugen am Stadtwehr Dessau (Gaumert & Zuppke 2003).
Tierwelt der Muldeaue
(1997)
Dem Gebiet der unteren Mulde bietet mit seinem vielfältigen Habitatangebot einer artenreichen Tierwelt Lebensraum. In der Flussaue mit ihren Auenwäldern, Wiesen, Großseggenrieden, Hochstaudenfluren, Röhrichten und Gewässern leben 46 Säugetierarten, wovon 24 Arten [56 %) einer Gefährdungskategorie der Roten Liste Sachsen-Anhalts (Teil 1 , 1992) zugeordnet ist. Der naturnahe Lauf der Mulde mit seiner Vielgestaltigkeit der Ufer, seinen Altwässern sowie der Weichholzaue bietet dem Elbebiber (Castor fiber albicus) ideale Lebensbedingungen, die sein Überleben in den Zeiten des stärksten Bestandsrückganges ermöglichten. Der engagierten Betreuungstätigkeit ehrenamtlicher Mitarbeiter des Arbeitskreises Biberschutz ist eine lückenlose Dokumentation zur Bestandsentwicklung des Elbebibers zu verdanken. 1981 wurde die Höchstzahl von 92 Bibern ermittelt. Doch in den folgenden Jahren setzte infolge starker Uferdevastierung durch Weidevieh und durch Abwasserbelastung eine Bestandshalbierung ein. NOLET, DIJKSTRA und HEIDECKE [71) ermittelten in den Nieren der Biber an der Mulde extrem hohe Cadmiumbelastungen [durchschnittlich 467 g Cd/ g Trockengewicht, die höchsten jemals bei Pflanzenfressern festgestellten Werte. Mit dem Einstellen der Weidewirtschaft und der Verbesserung der Wasserqualität der Mulde erholte sich der Biberbestand wieder. Im Winter 1995/96 wurden 76 Biber ermittelt, so dass der Bestand zunächst als gesichert erscheint.
Im Gegensatz zu den anderen Wirbeltieren spielt sich das Leben der Fische ausschließlich im Wasser ab und bleibt den Blicken des Menschen verborgen. Systematische Arterfassungen werden erst seit jüngerer Zeit durchgeführt, aber jede Methode der Bestandserfassung liefert nur ein unvollkommenes Bild. Daher blieb es auch lange Zeit unbekannt, dass etliche Fischarten nur noch in geringen Restbeständen vorkommen, einige sogar völlig verschwunden sind. Als diese Situation bekannt wurde (Paepke 1981), erregte sie kaum Aufmerksamkeit. Erst in den 1980er Jahren begannen auch im heutigen Sachsen-Anhalt Fischkundler mit der systematischen Erfassung der Vorkommen von Fischen und Rundmäulern (Engelke 1988, Wüstemann 1989, Zuppke 1986). Nach 1990 wurden diese Bemühungen dank der Verfügbarkeit effektiverer Fanggeräte intensiviert.
Background: Berotralstat (BCX7353) is an oral, once-daily inhibitor of plasma kallikrein in development for the prophylaxis of hereditary angioedema (HAE) attacks.
Objective: Our aim was to determine the efficacy, safety, and tolerability of berotralstat in patients with HAE over a 24-week treatment period (the phase 3 APeX-2 trial).
Methods: APeX-2 was a double-blind, parallel-group study that randomized patients at 40 sites in 11 countries 1:1:1 to receive once-daily berotralstat in a dose of 110 mg or 150 mg or placebo (Clinicaltrials.gov identifier NCT03485911). Patients aged 12 years or older with HAE due to C1 inhibitor deficiency and at least 2 investigator-confirmed HAE attacks in the first 56 days of a prospective run-in period were eligible. The primary efficacy end point was the rate of investigator-confirmed HAE attacks during the 24-week treatment period.
Results: A total of 121 patients were randomized; 120 of them received at least 1 dose of the study drug (n = 41, 40, and 39 in the 110-mg dose of berotralstat, 150-mg of dose berotralstat, and placebo groups, respectively). Berotralstat demonstrated a significant reduction in attack rate at both 110 mg (1.65 attacks per month; P = .024) and 150 mg (1.31 attacks per month; P < .001) relative to placebo (2.35 attacks per month). The most frequent treatment-emergent adverse events that occurred more with berotralstat than with placebo were abdominal pain, vomiting, diarrhea, and back pain. No drug-related serious treatment-emergent adverse events occurred.
Conclusion: Both the 110-mg and 150-mg doses of berotralstat reduced HAE attack rates compared with placebo and were safe and generally well tolerated. The most favorable benefit-to-risk profile was observed at a dose of 150 mg per day.
This paper presents some results from a wider study which aims to define the features of German medical textbooks from a diachronic perspective. The medical textbook is presented here as a genre-class (Textsortenklasse) subsuming all texts written for didactic purposes in the field of medicine, i.e. texts aiming to present the theoretical and practical background required in this particular specialist professional field. Since the lingua franca of academic communication was Latin until the 18th century, the corpus used for this study mainly comprises surgery textbooks. The paper focuses solely on structural aspects of textbooks, seeking to show how these aspects functionally contribute to the realization of the general textual function and thereby constitute a historically established conventionalized scheme underlying genres. However, a thorough and effective description of a genre-class requires a much more extensive approach including more interrelated levels of analysis.
ATP-binding cassette (ABC) systems translocate a wide range of solutes across cellular membranes. The thermophilic Gram-negative eubacterium Thermus thermophilus, a model organism for structural genomics and systems biology, discloses ∼46 ABC proteins, which are largely uncharacterized. Here, we functionally analyzed the first two and only ABC half-transporters of the hyperthermophilic bacterium, TmrA and TmrB. The ABC system mediates uptake of the drug Hoechst 33342 in inside-out oriented vesicles that is inhibited by verapamil. TmrA and TmrB form a stable heterodimeric complex hydrolyzing ATP with a Km of 0.9 mm and kcat of 9 s−1 at 68 °C. Two nucleotides can be trapped in the heterodimeric ABC complex either by vanadate or by mutation inhibiting ATP hydrolysis. Nucleotide trapping requires permissive temperatures, at which a conformational ATP switch is possible. We further demonstrate that the canonic glutamate 523 of TmrA is essential for rapid conversion of the ATP/ATP-bound complex into its ADP/ATP state, whereas the corresponding aspartate in TmrB (Asp-500) has only a regulatory role. Notably, exchange of this single noncanonic residue into a catalytic glutamate cannot rescue the function of the E523Q/D500E complex, implicating a built-in asymmetry of the complex. However, slow ATP hydrolysis in the newly generated canonic site (D500E) strictly depends on the formation of a posthydrolysis state in the consensus site, indicating an allosteric coupling of both active sites.
In the insect brain, the mushroom body is a higher order brain area that is key to memory formation and sensory processing. Mushroom body (MB) extrinsic neurons leaving the output region of the MB, the lobes and the peduncle, are thought to be especially important in these processes. In the honeybee brain, a distinct class of MB extrinsic neurons, A3 neurons, are implicated in playing a role in learning. Their MB arborisations are either restricted to the lobes and the peduncle, here called A3 lobe connecting neurons, or they provide feedback information from the lobes to the input region of the MB, the calyces, here called A3 feedback neurons. In this study, we analyzed the morphology of individual A3 lobe connecting and feedback neurons using confocal imaging. A3 feedback neurons were previously assumed to innervate each lip compartment homogenously. We demonstrate here that A3 feedback neurons do not innervate whole subcompartments, but rather innervate zones of varying sizes in the MB lip, collar, and basal ring. We describe for the first time the anatomical details of A3 lobe connecting neurons and show that their connection pattern in the lobes resemble those of A3 feedback cells. Previous studies showed that A3 feedback neurons mostly connect zones of the vertical lobe that receive input from Kenyon cells of distinct calycal subcompartments with the corresponding subcompartments of the calyces. We can show that this also applies to the neck of the peduncle and the medial lobe, where both types of A3 neurons arborize only in corresponding zones in the calycal subcompartments. Some A3 lobe connecting neurons however connect multiple vertical lobe areas. Contrarily, in the medial lobe, the A3 neurons only innervate one division. We found evidence for both input and output areas in the vertical lobe. Thus, A3 neurons are more diverse than previously thought. The understanding of their detailed anatomy might enable us to derive circuit models for learning and memory and test physiological data.
Grass savannas on lateritic crusts are characteristic landscape elements of the Sudanian savannas. In the W National Park and its surroundings in SE-Burkina Faso, plant diversity of savannas on and adjacent to bowé was assessed by a survey of 19 bowal areas with relevés along transects in each of these. The vegetation structure and species composition of the herb and shrub strata, soil depth, particle size and the concentration of Na+, K+, Mg2+, Ca2+, H+, C and N were recorded on each bowal and its surroundings. Our results show that soils on lateritic crusts are rather shallow and acidic compared to the surrounding savanna woodlands. Nutrient availability is hence comparatively low. The observed flora comprises 130 species mainly belonging to the families Combretaceae, Cyperaceae, Leguminosae and Poaceae with a predominance of therophytes and a comparatively high share of C4 species. In the pastures surrounding the National Park a higher species richness was found than inside the Park due to the occurrence of pioneers, ruderal and unpalatable plants. Savannas on lateritic crusts exhibit due to their extreme edaphic and hydrological conditions a specific flora distinct from their surroundings.
This article examines whether autonomy as an educational aim should be defended at the global scale. It begins by identifying the normative issues at stake in global autonomy education by distinguishing them from the problems of autonomy education in multicultural nation-states. The article then explains why a planet-wide expansion of the ideal of autonomy is conceivable on the condition that the concept of autonomy is widened in a way that renders its precise meaning flexibly adjustable to a variety of distinct social and cultural contexts. A context-transcendent, core meaning of autonomy remains in place, however, according to which a person is only autonomous if she relates to the values and goals that direct her life in a way so that she sees them as her own and is able to identify and critically assess her principal reasons for action. Finally, the article addresses two challenges to the global expansion of autonomy education: the objection that autonomy is presently not the most important educational aim and the objection that global autonomy education is a form of cultural imperialism. It finds both objections wanting.
Highlights
• Artificial intelligence systems for mechanically ventilated patients are increasing.
• The clinical and financial impact of these models are often unexamined.
• We developed a generic health-economic model for artificial intelligence systems.
• This model assesses the cost-effectiveness for many different scenarios.
• The developed framework is easily adjustable to other (clinical) situations.
Abstract
Purpose: The health and economic consequences of artificial intelligence (AI) systems for mechanically ventilated intensive care unit patients often remain unstudied. Early health technology assessments (HTA) can examine the potential impact of AI systems by using available data and simulations. Therefore, we developed a generic health-economic model suitable for early HTA of AI systems for mechanically ventilated patients.
Materials and methods: Our generic health-economic model simulates mechanically ventilated patients from their hospitalisation until their death. The model simulates two scenarios, care as usual and care with the AI system, and compares these scenarios to estimate their cost-effectiveness.
Results: The generic health-economic model we developed is suitable for estimating the cost-effectiveness of various AI systems. By varying input parameters and assumptions, the model can examine the cost-effectiveness of AI systems across a wide range of different clinical settings.
Conclusions: Using the proposed generic health-economic model, investors and innovators can easily assess whether implementing a certain AI system is likely to be cost-effective before an exact clinical impact is determined. The results of the early HTA can aid investors and innovators in deployment of AI systems by supporting development decisions, informing value-based pricing, clinical trial design, and selection of target patient groups.
Social identification has been shown to be a protective resource for mental health. In this study, the relationships between social identification and emotional, as well as cognitive symptoms of test anxiety are investigated. Participants were university students diagnosed with test anxiety (N = 108). They completed questionnaires regarding a range of psychopathologic stress symptoms, and their social identification with fellow students and with their study program. Results reveal negative relations between social identification and almost all investigated emotional and cognitive symptoms of test anxiety. Based on this study, interventions could be developed that strengthen the social identity of university students.
Der evolutionäre Erfolg der Pterygoten macht Fluginsekten auch in Binnengewässern zur nach Arten- und Individuenzahl dominierenden Gruppe. In unseren Gewässern, in denen Großmuscheln und Großkrebse ihre ursprüngliche Rolle nicht mehr spielen, stehen sie auch der Biomasse nach an der Spitze der Wirbellosen. Limnologen, die die Lebensgemeinschaft der Gewässer bearbeiten wollen, müssen darum gute Entomologen in ihren Reihen haben, denn die präzise Identifizierung der Organismen ist eine Grundvoraussetzung für sinnvolle ökologische Studien, welche das eigentliche Anliegen der Limnologen sind. Ende der vierziger Jahre wurde das ehrgeizige Vorhaben der limnologischen Gesamtbearbeitung des einzigen in ganzer Länge in den Westzonen liegenden größeren Flusssystems, Fulda und Weser, von fünf Göttinger Studenten in Angriff genommen. Das Schwergewicht der Arbeiten lag auf der 220 km langen Fulda in Osthessen, deren Erforschung seit der Gründung der Limnologischen Fluss-Station in Schlitz 1951 unter Leitung von Joachim Illies von Schlitz aus betrieben wurde. Ihm bot die Formenvielfalt der Wasserinsekten eine hervorragende Handhabe zur Abgrenzung...
Desafios à tradução do texto satírico : alguns exemplos de "Dritte Walpurgisnacht" de Karl Kraus
(2012)
Último texto de fôlego de Kraus, "Dritte Walpurgisnacht" ("Terceira noite de Valpúrgis") foi a reação do satirista à tomada do poder por Hitler. Do ponto de vista tradutório, oferece grande variedade de problemas, visto que o autor faz um uso exuberante de citações, trocadilhos, aliterações, neologismos e variações de ditos, provérbios, máximas e lugarescomuns. Este artigo apresenta alguns desses problemas e discute possibilidades para sua solução, não sem antes definir uma abordagem teórica.
Proton pumping respiratory complex I (NADH:ubiquinone oxidoreductase) is a major component of the oxidative phosphorylation system in mitochondria and many bacteria. In mammalian cells it provides 40% of the proton motive force needed to make ATP. Defects in this giant and most complicated membrane-bound enzyme cause numerous human disorders. Yet the mechanism of complex I is still elusive. A group exhibiting redox-linked protonation that is associated with iron-sulfur cluster N2 of complex I has been proposed to act as a central component of the proton pumping machinery. Here we show that a histidine in the 49-kDa subunit that resides near iron-sulfur cluster N2 confers this redox-Bohr effect. Mutating this residue to methionine in complex I from Yarrowia lipolytica resulted in a marked shift of the redox midpoint potential of iron-sulfur cluster N2 to the negative and abolished the redox-Bohr effect. However, the mutation did not significantly affect the catalytic activity of complex I and protons were pumped with an unchanged stoichiometry of 4 H+/2e−. This finding has significant implications on the discussion about possible proton pumping mechanism for complex I.
apl. Prof. Dr. Jörg W. Busch (Goethe Uni Frankfurt) hat bisher 2 Vorträge in Trebur gehalten. Der erste am 14. Oktober 2004 mit dem Titel "Trebur ein Königshof am Mittelrhein" und am 6. Oktober 2005 mit dem Titel "Die Pfalz Trebur unter Heinrich IV. vom Schauplatz großer Politik zum gemiedenen Ort" ...
Orientation: The purpose of this editorial was to provide an introduction and a general overview of the special issue on Open Science Practices: A Vision for the Future of SAJIP, as hosted in the 45th edition of the South African Journal of Industrial Psychology (SAJIP). Specifically, the aim was to provide a viable, practical and implementable strategy for enhancing the scientific credibility, transparency and international stature of SAJIP.
Rezension zu: Psychology of Retention:Theory, Research and Practice / Melinde Coetzee, Ingrid L. Potgieter and Nadia Ferreira (Eds.), ISBN:978-3-319-98919-8 Publisher:Springer Nature, 2018, R1600 (Preis SA)
The strengths use scale: psychometric properties, longitudinal invariance and criterion validity
(2021)
Strengths use is an essential personal resource to consider when designing higher-educational programs and interventions. Strengths use is associated with positive outcomes for both the student (e.g., study engagement) and the university (e.g., academic throughput/performance). The Strengths Use Scale (SUS) has become a popular psychometric instrument to measure strengths use in educational settings, yet its use has been subjected to limited psychometric scrutiny outside of the U.S. Further, its longitudinal stability has not yet been established. Given the wide use of this instrument, the goals of this study were to investigate (a) longitudinal factorial validity and the internal consistency of the scale, (b) its equivalence over time, and (c) criterion validity through its relationship with study engagement over time. Data were gathered at two-time points, 3 months apart, from a sample of students in the Netherlands (n = 360). Longitudinal confirmatory factor analyses showed support for a two-factor model for overall strengths use, comprised of Affinity for Strengths and Strengths Use Behaviors. The SUS demonstrated high levels of internal consistency at both the lower- and upper bound limits at both time points. Further, strict longitudinal measurement invariance was established, which confirmed the instrument's temporal stability. Finally, criterion validity was established through relating strengths use to study engagement at different time stamps. These findings support the use of the SUS in practice to measure strengths use and to track the effectiveness of strengths use interventions within the higher education sector.
Orientation: The work of industrial/organisational (I/O) psychologists presents an interesting and relevant context for studying meaning and engagement as components of happiness. Research purpose: The aim of this study was to determine how I/O psychologists experience the meaning of their work and to investigate the relationships between their experiences of work-role fit, meaning of work, psychological meaningfulness and work engagement, utilising the happiness framework proposed by Seligman (2002). Motivation for the study: I/O psychologists spend more than 88% of their working day with people, and they are primary role models for happiness in the workplace. Information about their work engagement and experiences of meaning is therefore needed. Research design, approach and method: A survey design was used. A convenience sample (n = 106) was taken of I/O psychologists in South Africa. A biographical questionnaire, the Work-Role Fit Scale, the Work-Life Questionnaire, the Psychological Meaningfulness Scale, the Work Engagement Scale and a survey measuring the actual and desired time spent on six broad categories of work were administered. Main findings: Work-role fit predicted psychological meaningfulness and work engagement. The calling orientation to work predicted both psychological meaningfulness and work engagement. Work-role fit mediated the relationship between the meaning of work and psychological meaningfulness. Work-role fit partially mediated the relationship between a calling orientation to work and work engagement. Practical implications: A calling orientation to work should be fostered in I/O psychologists because it contributes to experiences of work-role fit, psychological meaningfulness and work engagement. Contribution/value-add: The results of this study contribute to scientific knowledge about work-role fit, engagement and meaning as components of happiness of I/O psychologists.
Despite its popularity in practice, the Grit-O Scale has shown inconsistent factorial structures and differing levels of internal consistency in samples outside the USA. The validity of the Grit-O Scale in different contexts is, therefore, questionable. As such, the purpose of this paper was to determine whether the Grit-O Scale could be used as a valid and reliable measure to compare grit across different nations. Specifically, the aim was to investigate the factorial validity, reliability, and concurrent validity of the Grit-O Scale and to investigate measurement invariance across three national cohorts (Europe, the USA, and Hong Kong). Data were gathered from 1888 respondents stemming from one USA- (n = 471), two Hong Kong- (n = 361) and four European (n = 1056) universities. A series of traditional CFA and less restrictive ESEM models were estimated and systematically compared to determine the best factorial form of the Grit-O Scale. The results showed that a bifactor ESEM model, with one general factor of overall grit and two specific factors (consistency of interest and perseverance of effort), fitted the data best, showed strong measurement invariance across the three samples, and showed itself to be a reliable measure. Furthermore, concurrent validity was established by showing that the three grit factors were directly and positively related to task performance. Meaningful latent comparisons between the three cultural cohorts could therefore be made. The results imply that cross-national comparisons of grit may only be problematic when traditional CFA approaches are favoured. In contrast, ESEM modelling approaches may compensate for cross-national differences in understanding grit and control for differences in the interpretation of the scale’s items. Therefore, the bifactor ESEM approach may be more appropriate for cross-cultural and cross-national comparison studies, as it allows for these differences to be meaningfully captured, modelled, and controlled for.
Problematisation: The credibility and transparency of industrial and organisational psychological (IOP) research within South Africa was recently challenged by Efendic and Van Zyl (2019). The authors briefly showed inconsistencies in statistical results reported by authors of the South African Journal of Industrial Psychology (SAJIP), that various studies were insufficiently powered, that best-practice guidelines for the reporting of results were mostly only partially followed and that no transparency exists with regard to the research process. They demonstrated that authors of the SAJIP may knowingly or unknowingly be engaging in questionable research practices, which directly affects the credibility of both the discipline and the journal. Furthermore, they suggested practical guidelines for both authors and the SAJIP on how this could be managed.
Implications: Based on these suggestions, the authors invited prominent members of the IOP scientific community to provide scholarly commentary on their paper in order to aid in the development of ‘a clear strategy on how [the confidence crisis in IOP] could be managed, what the role of SAJIP is in this process and how SAJIP and its contributors could proactively engage to address these issues’. Seven members of the editorial board and two international scholars provided commentaries in an attempt to further the debate about the nature, causes, consequences and management of the credibility crisis within the South African context.
Purpose: The purpose of this final rebuttal article was to summarise and critically reflect on the commentaries of the nine articles to advance the debate on the confidence crisis within the South African IOP discipline.
Recommendations: All SAJIP’s stakeholders (authors, editors, reviewers, the publication house, universities and the journal) can play an active role in enhancing the credibility of the discipline. It is suggested that SAJIP should develop a clear and structured strategy to promote credible, transparent and ethical research practices within South Africa.
Academic self-efficacy (ASE) refers to a student’s global belief in his/her ability to master the various academic challenges at university and is an essential antecedent of wellbeing and performance. The five-item General Academic Self-Efficacy Scale (GASE) showed promise as a short and concise measure for overall ASE. However, of its validity and reliability outside of Scandinavia is limited. Therefore, this paper aimed to investigate the psychometric properties, longitudinal invariance, and criterion validity of the GASE within a sample of university students (Time 1: n = 1056 & Time 2: n = 592) in the USA and Western Europe. The results showed that a unidimensional factorial model of overall ASE fitted the data well was reliable and invariant across time. Further, criterion validity was established by finding a positive relationship with task performance at different time stamps. Therefore, the GASE can be used as a valid and reliable measure for general ASE.
Orientation: Lack in congruence amongst industrial and organisational psychologists (IOPs) as to the conceptualisation of its profession poses a significant risk as to the relevance, longevity and professional identity of the profession within the South African context. Research purpose: This study aimed to explore the professional identity of IOPs within the South African context. Specifically, the aim of this study was four-fold: (1) to develop a contemporary definition for IOP, (2) to investigate IOP roles, (3) to determine how the profession should be labelled and (4) to differentiate IOP from human resource management (HRM) from IOPs’ perspectives within South Africa. Motivation for the study: IOPs do not enjoy the same benefits in stature or status as other professions such as medicine, finances and engineering in the world of work. IOPs need to justify its relevance within organisational contexts as a globally shared understanding of ‘what it is’, ‘what it does’ and ‘what makes it different from other professions’, which is non-existent. In order to enhance its perceived relevance, clarity as to IOPs professional identity is needed. Research design, approach and method: A post-positivistic qualitative content analytic and descriptive research design was employed in this study. Data from practising industrial and organisational psychology (IOP) within South Africa (N = 151) were gathered through an electronic web-based survey and were analysed through thematic content analysis. Main findings: The results indicate that IOP in South Africa seeks to optimise the potential of individuals, groups, organisations and the community by implementing scientific processes to support both individual and organisational wellness and sustainability. ‘Work Psychology’ was considered a more fitting professional designation or label than industrial and/or organisational psychology. The industrial psychologist’s major roles related to the well-being and development of employees. A clear distinction between a more dynamic, pro-active approach of IOP compared to a more transactional approach of HRM was also evident. IOP within South Africa appears to have a community development function. Practical/managerial implications: The longevity, relevance and impact of IOP as a profession requires alignment amongst practitioners as to shared common professional identity. Contribution/value-add: This study provides a contemporary understanding of the roles, functions, labels and unique value proposition of industrial and organisational psychology within the South African context.
The purpose of this study was to examine the psychometric properties (i.e., factorial validity, measurement invariance, and reliability) of the Grit-Original scale (Grit-O) within the Netherlands. The Grit-O scale was subjected to a competing measurement modeling strategy that sequentially compared both independent cluster model confirmatory factor analytical- and exploratory structural equation modeling approaches. The results showed that both a two first order, bi-factor structure as well as a less restrictive two factor ESEM factorial structure best-fitted the data. The instrument showed to be reliable at both a lower- (Cronbach’s alpha) and upper-level (composite reliability) limit. However, measurement invariance between genders could only be established for the B-ICM-CFA model. Finally, concurrent validity was established through relating the GRIT-O to task performance. The linear use of the Grit-O scale should therefore carefully be considered.
The information and communication technology (ICT) sector within the Netherlands is a major driver of globalization, the country’s economic growth and innovation. The Dutch ICT sector’s performance is increasingly becoming dependent upon employee driven innovations in order to address the needs of the sectors they service. In other words, the ICT sector within the Netherlands is largely dependent upon the performance and innovative capacity of its employees; both of which are functions of employee engagement. Given the high demand, and low supply of talent within this sector, ICT organizations need to develop innovative ways to enhance the performance capacities of its people. Developing an engaged and highly innovative workforce seems to be an efficient way to activate employees’ performance. As such, the aim of this paper was to investigate the mediating function of employee driven innovative work behaviors in the relationship between work engagement and task performance within the a Dutch ICT consulting firm. A cross-sectional survey-based research design, employing a census-based sampling method, was employed to obtain data from a global ICT consulting firm within the Netherlands (n = 232). The Utrecht Work Engagement Scale, the Innovative Work Behavior Scale and the Task Performance Scale was used to assess the associative subjective experiences of ICT employees. The results showed that work engagement is a significant driver for innovative work behaviors, which in turn affects the task performance of employees. Further, innovative work behaviors are therefore important to translate the engaging energies of employees into performance. This paper discusses the theoretical and practical implications of these findings.
Despite the popularity of the term Positive Psychological Coaching within the literature, there is no consensus as to how it should be defined (framed) or what the components of a positive coaching “model” should include. The aim of this systematic review was to define positive psychological coaching and to construct a clear demarcated positive psychological coaching model based on the literature. A systematic literature review led to the extraction of 2,252 records. All records were screened using specific inclusion/exclusion criteria, which resulted in the exclusion of records based on duplicates (n = 1,232), titles (n = 895), abstracts (n = 78), and criteria violations (n = 23). Twenty-four academic, peer-reviewed publications on positive psychological coaching were included. Data relating to conceptual definitions and coaching models/phases/frameworks were extracted and processed through thematic content analysis. Our results indicate that positive psychological coaching can be defined as a short to medium term professional, collaborative relationship between a client and coach, aimed at the identification, utilization, optimization, and development of personal strengths and resources in order to enhance positive states, traits and behaviors. Utilizing Socratic goal setting and positive psychological evidence-based approaches to facilitate personal growth, optimal functioning, enhanced wellbeing, and the actualization of people's potential. Further, eight critical components of a positive psychological coaching model were identified and discussed. The definition and coaching process identified in this study will provide coaches with a fundamental positive psychological framework for optimizing people's potential.
Editorial: Positive organizational interventions: contemporary theories, approaches and applications
(2020)
The purpose of this study was to identify distinctive mental health profiles for industrial psychologists based on the Mental Health Continuum. Further, it aimed to determine how these profiles differ with respect to work-role fit, meaningfulness and work engagement. It also aimed to investigate whether industrial psychologists within managerial or specialist differ in respect of different types of mental health. An online cross-sectional survey design was employed to draw a census sample (n = 274) from all South African industrial psychologists. A biographical questionnaire, the Work-Role Fit Scale, the Psychological Meaningfulness Scale, the Work Engagement Scale, and the Mental Health Continuum–Short Form were administered. Descriptive statistics, correlations, latent profile analysis, MANOVAs and ANOVAs were computed. Three mental health profiles for industrial psychologists were identified: languishing, moderately mentally healthy and flourishing. Significant differences between the three mental health profiles and experiences of meaningful work-role fit and work engagement were found, but not between experiences of managerial roles. The results show that individuals with different mental health profiles, experience work and its related outcomes, differently. Therefore, in order to enhance meaningful work-role fit and work engagement of industrial psychologists, a one-size-fits-all model may not be appropriate.
The COVID-19 lockdown has significantly disrupted the higher education environment within the Netherlands and led to changes in available study-related resources and study demands of students. These changes in study resources and study demands, the uncertainty and confusion about educational activities, the developing fear and anxiety about the disease, and the implementation of the COVID-19 lockdown measures may have a significant impact on the mental health of students. As such, this study aimed to investigate the trajectory patterns, rate of change, and longitudinal associations between study resources–demands and mental health of 141 university students from the Netherlands before and during the COVID-19 lockdown. The present study employed a longitudinal design and a piecewise latent growth modeling strategy to investigate the changes in study resources and mental health over a 3 month period. The results showed that moderate levels of student resources significantly decreased before, followed by a substantial rate of increase during, lockdown. In contrast, study demands and mental health were reported to be moderate and stable throughout the study. Finally, the growth trajectories of study resources–demands and mental health were only associated before the lockdown procedures were implemented. Despite growing concerns relating to the negative psychological impact of COVID-19 on students, our study shows that the mental health during the initial COVID-19 lockdown remained relatively unchanged.
Die Weißtanne (Abies alba) – Symbol für naturnahe Waldwirtschaft – ist im Bayerischen Wald beheimatet. Die Tanne ist dort neben Fichte und Buche das prägende Element der Bergmischwälder auf Höhen von 600 bis 1250 m. Einstmals war sie mit etwa 20 % (ROTHE & BORCHERT 2003) am Waldaufbau beteiligt. Seit rund 150 Jahren ist jedoch ein drastischer Rückgang der Tanne - nicht nur im Bayerischen Wald – zu verzeichnen. Die Ursachen für den Rückgang der Tanne sind überwiegend anthropogen bedingt. In erster Linie ist hier die Forstwirtschaft zu erwähnen, die bestrebt ist durch waldbauliche Maßnahmen den Fichtenanteil anzuheben. An zweiter Stelle stehen die neuartigen Waldschäden, welche, bedingt durch Schadstoffimmissionen in den 70er und 80er Jahren des letzten Jahrhunderts, zu verstärktem Absterben der Tanne führten. Noch heute ist die Tanne die am stärksten geschädigte Baumart in Bayern (BAYSTMLF 2002). Ein weiterer nicht zu vergessender Faktor für den Rückgang der Tanne sind die z.T. hohen Wildbestände, durch deren Verbiss und Schälen junger Tannen das Heranwachsen einer neuen Generation verhindert wird. Mit dem Rückgang der Tanne verändert sich jedoch nicht nur die Baumartenzusammensetzung, sondern auch Tier- und Pflanzenarten sind direkt und indirekt betroffen. Die Arthropodenfauna der bisher kaum untersuchten Tanne wird als relativ artenarm beschrieben (BRÄNDLE & BRANDL 2001), jedoch gibt es wenige spezielle Untersuchungen an dieser Baumart (MÜLLER & GOßNER 2004).
hallmark of ageing is the redistribution of body fat. Particularly, subcutaneous fat decreases paralleled by a decrease of skin collagen I are typical for age-related skin atrophy. In this paper, we hypothesize that collagen I may be a relevant molecule stimulating the differentiation of adipose-derived stem cells (ASCs) into adipocytes augmenting subcutaneous fat. In this context lipogenesis, adiponectin, and collagen I receptor expression were determined. Freshly isolated ASCs were characterized by stemness-associated surface markers by FACS analysis and then transdifferentiated into adipocytes by specific medium supplements. Lipogenesis was evaluated using Nile Red staining and documented by fluorescence microscopy or quantitatively measured by using a multiwell spectrofluorometer. Expression of adiponectin was measured by real-time RT-PCR and in cell-free supernatants by ELISA, and expression of collagen I receptors was observed by western blot analysis. It was found that supports coated with collagen I promote cell adhesion and lipogenesis of ASCs. Interestingly, a reverse correlation to adiponectin expression was observed. Moreover, we found upregulation of the collagen receptor, discoidin domain-containing receptor 2; receptors of the integrin family were absent or downregulated. These findings indicate that collagen I is able to modulate lipogenesis and adiponectin expression and therefore may contribute to metabolic dysfunctions associated with ageing.
Background: The treatment of different skin conditions with spa waters is a long tradition dating back to at least late Hellenism. Interestingly, independent scientific examinations studying the effect of spa waters are scarce.
Objective: In the present in vitro study, we compared the effect of culture media supplemented with (a) thermal spa waters (La Roche-Posay, Avène) and (b) two natural mineral drinking waters (Heppinger, Adelholzener) on physiological parameters in HaCaT keratinocytes.
Methods: The different medium preparations were investigated with regard to cell proliferation and cell damage. Moreover, the impact on inflammation parameters with and without ultraviolet B (UVB) irradiation was examined.
Results: Two popular thermal spring waters were found to suppress cell proliferation and cell damage. Moreover, these waters reversed the induction of interleukin-6, as measured using enzyme-linked immunosorbent assay and promoter transactivation, and the formation of reactive oxygen species after UVB stimulation. Of note, the two natural mineral waters, which are distributed as drinking waters, had some effect on the above-mentioned parameters but to a lesser extent.
Conclusion: In summary, our results show that spa waters, and particularly those derived from thermal springs, reduce parameters associated with inflammation. It seems likely that trace elements such as selenium and zinc are critical for the observed effects.
Stress-induced cell surface expression of MHC class I-related glycoproteins of the MIC and ULBP families allows for immune recognition of dangerous “self cells” by human cytotoxic lymphocytes via the NKG2D receptor. With two MIC molecules (MICA and MICB) and six ULBP molecules (ULBP1–6), there are a total of eight human NKG2D ligands (NKG2DL). Since the discovery of the NKG2D–NKG2DL system, the cause for both redundancy and diversity of NKG2DL has been a major and ongoing matter of debate. NKG2DL diversity has been attributed, among others, to the selective pressure by viral immunoevasins, to diverse regulation of expression, to differential tissue expression as well as to variations in receptor interactions. Here, we critically review the current state of knowledge on the poorly studied human NKG2DL ULBP4. Summarizing available facts and previous studies, we picture ULBP4 as a peculiar ULBP family member distinct from other ULBP family members by various aspects. In addition, we provide novel experimental evidence suggesting that cellular processing gives rise to mature ULBP4 glycoproteins different to previous reports. Finally, we report on the proteolytic release of soluble ULBP4 and discuss these results in the light of known mechanisms for generation of soluble NKG2DL.
A systematic review on the burden of illness in individuals with tuberous sclerosis complex (TSC)
(2020)
Objective: This review will summarize current knowledge on the burden of illness (BOI) in tuberous sclerosis complex (TSC), a multisystem genetic disorder manifesting with hamartomas throughout the body, including mainly the kidneys, brain, skin, eyes, heart, and lungs.
Methods: We performed a systematic analysis of the available literature on BOI in TSC according to the PRISMA guidelines. All studies irrespective of participant age that reported on individual and societal measures of disease burden (e.g. health care resource use, costs, quality of life) were included.
Results: We identified 33 studies reporting BOI in TSC patients. Most studies (21) reported health care resource use, while 14 studies reported quality of life and 10 studies mentioned costs associated with TSC. Only eight research papers reported caregiver BOI. Substantial BOI occurs from most manifestations of the disorder, particularly from pharmacoresistant epilepsy, neuropsychiatric, renal and skin manifestations. While less frequent, pulmonary complications also lead to a high individual BOI. The range for the mean annual direct costs varied widely between 424 and 98,008 International Dollar purchasing power parities (PPP-$). Brain surgery, end-stage renal disease with dialysis, and pulmonary complications all incur particularly high costs. There is a dearth of information regarding indirect costs in TSC. Mortality overall is increased compared to general population; and most TSC related deaths occur as a result of complications from seizures as well as renal complications. Long term studies report mortality between 4.8 and 8.3% for a follow-up of 8 to 17.4 years.
Conclusions: TSC patients and their caregivers have a high burden of illness, and TSC patients incur high costs in health care systems. At the same time, the provision of inadequate treatment that does not adhere to published guidelines is common and centralized TSC care is received by no more than half of individuals who need it, especially adults. Further studies focusing on the cost effectiveness and BOI outcomes of coordinated TSC care as well as of new treatment options such as mTOR inhibitors are necessary.
Background: Tuberous sclerosis complex (TSC) is a monogenetic, multisystem disorder characterized by benign growths due to TSC1 or TSC2 mutations. This German multicenter study estimated the costs and related cost drivers associated with organ manifestations in adults with TSC.
Methods: A validated, three-month, retrospective questionnaire assessed the sociodemographic and clinical characteristics, organ manifestations, direct, indirect, out-of-pocket (OOP), and nursing care-level costs among adult individuals with TSC throughout Germany from a societal perspective (costing year: 2019).
Results: We enrolled 192 adults with TSC (mean age: 33.4 ± 12.7 years; range: 18–78 years, 51.6% [n = 99] women). Reported TSC disease manifestations included skin (94.8%) and kidney and urinary tract (74%) disorders, epilepsy (72.9%), structural brain defects (67.2%), psychiatric disorders (50.5%), heart and circulatory system disorders (50.5%), and lymphangioleiomyomatosis (11.5%). TSC1 and TSC2 mutations were reported in 16.7% and 25% of respondents, respectively. Mean direct health care costs totaled EUR 6452 (median EUR 1920; 95% confidence interval [CI] EUR 5533–7422) per patient over three months. Medication costs represented the major direct cost category (77% of total direct costs; mean EUR 4953), and mechanistic target of rapamycin (mTOR) inhibitors represented the largest share (68%, EUR 4358). Mean antiseizure drug (ASD) costs were only EUR 415 (6%). Inpatient costs (8%, EUR 518) and outpatient treatment costs (7%; EUR 467) were important further direct cost components. The mean care grade allowance as an approximator of informal nursing care costs was EUR 929 (median EUR 0; 95% CI EUR 780–1083) over three months. Mean indirect costs totaled EUR 3174 (median EUR 0; 95% CI EUR 2503–3840) among working-age individuals (< 67 years in Germany). Multiple regression analyses revealed mTOR inhibitor use and persistent seizures as independent cost-driving factors for total direct costs. Older age and disability were independent cost-driving factors for total indirect costs, whereas epilepsy, psychiatric disease, and disability were independent cost-driving factors for nursing care costs.
Conclusions: This three-month study revealed substantial direct healthcare, indirect healthcare, and medication costs associated with TSC in Germany. This study highlights the spectrum of organ manifestations and their associated treatment needs in the German healthcare setting. Trial registration: DRKS, DRKS00016045. Registered 01 March 2019, http://www.drks.de/DRKS00016045.
The National Institutes of Health Stroke Scale (NIHSS) score is the most frequently used score worldwide for assessing the clinical severity of a stroke. Prior research suggested an association between acute symptomatic seizures after stroke and poorer outcome. We determined the frequency of acute seizures after ischemic stroke in a large population-based registry in a central European region between 2004 and 2016 and identified risk factors for acute seizures in univariate and multivariate analyses. Additionally, we determined the influence of seizures on morbidity and mortality in a matched case–control design. Our analysis of 135,117 cases demonstrated a seizure frequency of 1.3%. Seizure risk was 0.6% with an NIHSS score at admission <3 points and increased up to 7.0% with >31 score points. Seizure risk was significantly higher in the presence of acute non-neurological infections (odds ratio: 3.4; 95% confidence interval: 2.8–4.1). A lower premorbid functional level also significantly increased seizure risk (OR: 1.7; 95%CI: 1.4–2.0). Mortality in patients with acute symptomatic seizures was almost doubled when compared to controls matched for age, gender, and stroke severity. Acute symptomatic seizures increase morbidity and mortality in ischemic stroke. Their odds increase with a higher NIHSS score at admission.
Recent data have suggested that performing recanalizing therapies in ischemic stroke might lead to an increased risk of acute symptomatic seizures. This applies to both intravenous thrombolysis and mechanical thrombectomy. We therefore determined the frequency of acute symptomatic seizures attributable to these two recanalization therapies using a large, population-based stroke registry in Central Europe. We performed two matched 1:1 case–control analyses. In both analyses, patients were matched for age, stroke severity on admission and pre-stroke functional status. The first analysis compared patients treated with intravenous thrombolysis to a non-recanalization control group. To isolate the effect of mechanical thrombectomy, we compared patients with both mechanical thrombectomy and intravenous thrombolysis to those with only intravenous thrombolysis treatment in a second analysis. From 135,117 patients in the database, 13,356 patients treated with only intravenous thrombolysis, and 1013 patients treated with both intravenous thrombolysis and mechanical thrombectomy were each matched to an equivalent number of controls. Patients with intravenous thrombolysis did not suffer from clinically apparent acute symptomatic seizures significantly more often than non-recanalized patients (treatment = 199; 1.5% vs. control = 237; 1.8%, p = 0.07). Mechanical thrombectomy in addition to intravenous thrombolysis also was not associated with an increased risk of acute symptomatic seizures, as the same number of patients suffered from seizures in the treatment and control group (both n = 17; 1.7%, p = 1). In a large population-based stroke registry, the frequency of clinically apparent acute symptomatic seizures was not increased in patients who received either intravenous thrombolysis alone or in conjunction with mechanical thrombectomy.
Hintergrund
In Anbetracht ihres bedeutenden Potenzials zur Verbesserung der medizinischen Versorgung wird Telemedizin weiterhin zu wenig genutzt. Trotz einiger erfolgreicher Pilotprojekte in den vergangenen Jahren ist insbesondere über die Hindernisse der Etablierung und Verstetigung von Telemedizin wenig bekannt. Diese Studie hatte das Ziel, die Einstellung niedergelassener Neurologen hinsichtlich der Nutzung von Telemedizin in der Epileptologie und resultierende Hinderungsgründe zu verstehen. Gleichzeitig werden mögliche Lösungsansätze präsentiert.
Methoden
Mithilfe eines individuell erstellten 14-Item-Fragebogens befragten wir prospektiv alle Neurologen, die zuvor die Teilnahme an einem transregionalen Telemedizinpilotprojekt im Bereich der Epileptologie abgelehnt oder keine Rückmeldung gegeben hatten, zu Gründen für und gegen den generellen Einsatz von bzw. die Teilnahme an Telemedizin.
Ergebnisse
Von 58 kontaktierten Neurologen antworteten 33 (57 %). Die häufigsten Gründe für die fehlende Nutzung der Telemedizin waren ein vermuteter Zeitmangel oder ein vermuteter zu großer organisatorischer Aufwand (49 %). Zudem wurden Bedenken bezüglich der technischen Ausstattung (30 %) und eine Präferenz für alternative Wege der intersektoralen Kommunikation (30 %) angegeben. Befürchtete Probleme in Bezug auf die Kostenerstattung für telemedizinische Leistungen waren für 27 % ein Hindernis. Neurologen in ländlichen Gebieten waren signifikant häufiger bereit, zunächst eine telemedizinische Konsultation anzufordern, bevor sie eine Überweisung ausstellen (p = 0,006).
Schlussfolgerungen
Die flächendeckende Etablierung von Telemedizinstrukturen ist immer noch durch Hindernisse erschwert, die meist im organisatorischen Bereich liegen. Die bestehenden Herausforderungen im Gesundheitswesen in ländlichen Gebieten sind eine besondere Chance für die Implementierung von Telemedizin. Die meisten Probleme der Telemedizin können gelöst werden, sollten aber bereits bei der Konzeptionierung von Projekten mitbedacht werden, um ihre Verstetigung zu erleichtern.
Background and purpose: Transient splenial oedema, also known as reversible splenial lesion syndrome (RESLES), is a rare magnetic resonance imaging (MRI) finding that presents as a round or ovoid focal oedema in the posterior corpus callosum, and is associated with a wide range of clinical conditions. The aetiology of RESLES is not fully clear. We aimed to investigate conflicting pathophysiological hypotheses by measuring local glucose metabolism in patients with RESLES.
Methods: We retrospectively analysed patients with RESLES after reductions in antiseizure medications during in-hospital video electroencephalography monitoring. We measured local glucose uptake using positron emission tomography/computed tomography and compared matched cohorts of patients with and without MRI evidence of RESLES using nonparametric tests.
Results: Local glucose metabolism in the splenium of seven patients with RESLES was not significantly different from the glucose metabolism of the seven patients in the matched cohort. This was true using both regular and normalized standardized glucose uptake value calculation methods (p = 0.902 and p = 0.535, respectively).
Conclusion: We found no evidence of local glucose hypometabolism in RESLES, which supports previous pathophysiological considerations that suggest that RESLES is an intercellular, intramyelinic oedema rather than a typical intracellular cytotoxic oedema, which is not reversible.
Background: Through the rapid development in DNA sequencing methods and tools, microbiome studies on a various number of species were performed during the last decade. This advance makes it possible to analyze hundreds of samples from different species at the same time in order to obtain a general overview of the microbiota. However, there is still uncertainty on the variability of the microbiota of different animal orders and on whether certain bacteria within a species are subject to greater fluctuations than others. This is largely due to the fact that the analysis in most extensive comparative studies is based on only a few samples per species or per study site. In our study, we aim to close this knowledge gap by analyzing multiple individual samples per species including two carnivore suborders Canoidea and Feloidea as well as the orders of herbivore Perissodactyla and Artiodactyla held in different zoos. To assess microbial diversity, 621 fecal samples from 31 species were characterized by sequencing the V3–V4 region of the 16S rRNA gene using Illumina MiSeq.
Results: We found significant differences in the consistency of microbiota composition and in fecal microbial diversity between carnivore and herbivore species. Whereas the microbiota of Carnivora is highly variable and inconsistent within and between species, Perissodactyla and Ruminantia show fewer differences across species boundaries. Furthermore, low-abundance bacterial families show higher fluctuations in the fecal microbiota than high-abundance ones.
Conclusions: Our data suggest that microbial diversity is significantly higher in herbivores than in carnivores, whereas the microbiota in carnivores, unlike in herbivores, varies widely even within species. This high variability has methodological implications and underlines the need to analyze a minimum amount of about 10 samples per species. In our study, we found considerable differences in the occurrence of different bacterial families when looking at just three and six samples. However, from a sample number of 10 onwards, these within-species fluctuations balanced out in most cases and led to constant and more reliable results.
Die hier vorgestellte Studie entwickelt eine Theorie 'lyrischer Selbstentwürfe' und leistet eine kritische Bestandsaufnahme und Evaluation diesbezüglicher Forschungspositionen. Entgegen verbreiteter literaturwissenschaftlicher Grundannahmen wird die These vertreten, dass lyrische Texte faktual sein und auf Autor:innen referieren können. Für solche Fälle liefert die Studie ein begriffliches Instrumentarium, das sie an Beispielanalysen erprobt.
The Tanaidacea are ubiquitous and amongst the most abundant taxa in the deep sea. However, their diversity in submarine canyons remains largely unknown. Here, two new species and a new genus of Paratanaoidea are described. Paranarthrura cousteaui sp. nov. is distinguished by the combination of the following characters: post-cheliped sclerites not fused, presence of one seta in the maxilliped endite, one long midventral seta in cheliped, one penicillate seta in the basis of pereopods 4–6, uropod endopod bi-articulated and uropod exopod shorter than endopod article 1. This species was found at the upper reaches of three Portuguese canyons, Cascais, Setúbal and Nazaré Canyons, and the adjacent open slope, between 897 and 1001 m water depths. Tirana vallis gen. et sp. nov. presents a combination of the characters that define the other two genera of Paranarthrurellidae, Paranarthrurella and Armatognathia, but also unique characters within the family: the antenna, cheliped and uropod are more elongate than the rest of the species; the pereopods 4–6 carpus spines reach at least half of the length of the propodus and the propodus of pereopods 4–6 have ramified subdistal spines. This species was found at the middle reaches of Setúbal Canyon (3214–3219 m water depth).
Reconstructing the evolution of baleen whales (Mysticeti) has been problematic because morphological and genetic analyses have produced different scenarios. This might be caused by genomic admixture that may have taken place among some rorquals. We present the genomes of six whales, including the blue whale (Balaenoptera musculus), to reconstruct a species tree of baleen whales and to identify phylogenetic conflicts. Evolutionary multilocus analyses of 34,192 genome fragments reveal a fast radiation of rorquals at 10.5 to 7.5 million years ago coinciding with oceanic circulation shifts. The evolutionarily enigmatic gray whale (Eschrichtius robustus) is placed among rorquals, and the blue whale genome shows a high degree of heterozygosity. The nearly equal frequency of conflicting gene trees suggests that speciation of rorqual evolution occurred under gene flow, which is best depicted by evolutionary networks. Especially in marine environments, sympatric speciation might be common; our results raise questions about how genetic divergence can be established.
Die Sprechfertigkeit ist ein Phänomen, das in fremdsprachlichen Lehr- und Lernprozessen sowohl al Mittel (Vermittlungssprache des Lehrenden) als auch als Zielfertigkeit (die es zu erreichen gilt) an Bedeutung gewinnt. Die Sprechfertigkeit, die zu den sprachlichen Fertigkeiten gehört, ist eine schwer zu entwickelnde Fähigkeit, deren Förderung im Unterricht psychologische und kognitive Mühe erfordert. In dieser Arbeit wird betont, dass es möglich ist, die Sprechfertigkeit im universitären Kontext im Rahmen der Deutschlehrerausbildung "so natürlich wie möglich, so künstlich wie nötig!" zu entwickeln; dies berücksichtigend wurde mit Beispielen erwähnt, dass das Rollenspiel und die Dramatisierungstechniken auf die Förderung der Sprechfertigkeit positiv einwirken. Diese Techniken tragen besonders dazu bei, dass der angehende Deutschlehrer einerseits seine eigene Sprechfertigkeit erweitert und andererseits methodisch-didaktische Vorbildimpulse bekommt, die er in seiner beruflichen Laufbahn als Lehrtechnik effektiv anwenden kann.
Im Jahre 1864 haben die Türken angefangen, die deutsche Sprache in den Schulen zu erteilen, nach der Ausrufung der Republik Türkei in 1923 wurde Deutsch als Fremdsprache außerhalb von Ankara, Istanbul und Izmir auch in den Provinzstädten Kastamonu und Sivas als Fachunterricht eingeführt. In der Universität Istanbul wurde im Jahre 1933 durch Mitglieder des Lehrkörpers Einwanderer aus Deutschland die Abteilung für Deutsche Sprache und Literatur an der Philosophischen Fakultät eröffnet. Die vielfältigen Beziehungen zwischen Deutschland und der Türkei sind von großer Bedeutung und haben Einfluss auf die Entwicklung des Deutschen als Fremdsprache in den Lehrplänen. Seit dem Studienjahr 2001-2002 nimmt das Deutsche als zweites Pflichtfach in den Gymnasien seinen Platz ein. Der Fernunterricht geht seit 1728 kontinuierlich weiter und die Bürger in den Entwicklungsländern profitieren von den Vorteilen des Fernunterrichts. in der Geschichte geht der Fernunterricht in der Türkei zurück bis 1927. In diesem Artikel werden die Möglichkeiten für das Lernen des Deutschen als Fremdsprache durch Fernunterricht erklärt.
The relations between Turkey and Germany have a long history that involves collaboration and partnership in many areas. After 1960s, this relationship gained a new dimension as hundreds of thousands of Turkish workers immigrated to Germany. This paper presents a brief history of the relations between the two countries, and the cultural and language-related problems experienced by Turkish people in Germany. More specifically, it focuses on the background and current state of the Turkish Language and Culture course taught to the Turkish youth in German schools. Problems regarding the implementation of this course are discussed with reference to official statistics. Finally, suggestions are offered to address the challenges faced to improve the Turkish Language and Culture course so that Turkish children can successfully learn their origin-language, and eventually achieve competence in both Turkish and German in their academic studies.
Bundan 61 yıl önce, 1959 yılında Eskişehir Maarif Koleji binasında Milli Eğitim Bakanlığı'na bağlı olarak gece eğitimi vermek üzere üç yıllık bir Yabancı Diller Yüksekokulu (MEB YDYO) kuruldu. Okul İngilizce Bölümü'nden müteşekkildi. Yüksekokulun müdürlüğünü de İngilizce öğretmeni Ahmet Cemal AŞAN yapıyordu. Onun yardımcılığına da Almanca öğretmeni Okt. Recep GÖK atanmıştı. 1980-1981 eğitim öğretim yılında ilk öğrencilerini alan Almanca Bölümü'nde Almanca öğretmeni Seyyare DUMAN ve Ali GÜLTEKİN de öğretim görevlisi olarak ders veriyorlardı.
Plagiognathus ozgurkocaki sp. nov. is described based on a long series of specimens from Karaman, Turkey. The new species is remarkable among its congeners in Palearctic Region due to the combination of following characters: remarkably small size, dense and unicolorous pale yellow vestiture, darkened cuneus and yellow first antennal segment with a basal ring and pre-apical dots. The new species is associated with the endemic Phlomis leucophracta P.H.Davis & Hub.-Mor. (Lamiaceae) which makes it unique among all its congeners. Additionally, Plagiognathus bipunctatus albicans (Reuter, 1901) and Plagiognathus marivanensis Linnavuori, 2010 are recorded from Karaman, former constitutes a new record for Turkey.
Research on the Heteroptera fauna of Turkey has not been extensive enough to illustrate its true diversity. Although several factors contribute to this, the lack of an up-to-date and comprehensive review is a basic factor. To address this issue, we compiled a list of all the Heteroptera species recorded from Turkey in the literature and iNaturalist. In addition, we re-examined several specimens preserved in the Lodos Entomological Museum, İzmir, Turkey (LEMT). Consequently, we excluded 24 species from the checklist of Heteroptera fauna of Turkey, and proposed a new synonymy: Psallus (Psallus) pardalis Seidenstücker, 1966 = Psallus (Psallus) oenderi Wagner, 1976 syn. nov. Furthermore, we recorded following six species from Turkey for the first time: Blissus hirtulus Burmeister, 1835 (Blissidae), Loricula (Loricula) pselaphiformis Curtis, 1833 (Microphysidae), Globiceps (Globiceps) coryli V.G. Putshkov, 1970, Heterocordylus (Heterocordylus) cytisi Josifov, 1958, Mesopsallus fagi (Drapolyuk, 1990) and Psallus (Psallus) helenae Josifov, 1969 (Miridae); and described following six species as new for science: Orthonotus efei Çerçi & Koçak sp. nov., Orthotylus (Parapachylops) oenderi Çerçi, Tezcan & Koçak sp. nov., Orthotylus (Pinocapsus) girayi Çerçi & Tezcan sp. nov., Psallus (Psallus) eceae Çerçi & Koçak sp. nov., Psallus (Psallus) pehlivani Çerçi & Tezcan sp. nov. and Ribautocapsus tezcani Çerçi sp. nov. Altogether, 1668 species of Heteroptera have been recorded from Turkey (664 species in the European part and 1633 species in the Anatolian part) until now, out of them, the presence of 37 species needs confirmation. We determined the chorotypical composition of species as follows: Mediterranean (399 spp., 23.9%), European (380 spp., 22.8%), Local (280 spp., 16.8%), Widespread (182 spp., 10.9%), Endemic (128 spp., 7.7%), Turanian (127 spp., 7.5%), Turano-Mediterranean (89 spp., 5.3%), Europeo-Mediterranean (68 spp., 4.1%) and Alien (12 spp., 0.7%). We showed that provinces in the Eastern Anatolian, Southeastern Anatolian, and Black Sea regions had lower numbers of species recorded, compared to the provinces in the remaining regions. Finally, we underlined that 109 species, absent from Turkey, were recorded from three or more neighboring countries of Turkey. In summary, our findings emphasize that despite the abundant research devoted over the last 150 years to the Heteroptera fauna of Turkey, our understanding of it remains incomplete in the majority, if not in all, of the regions. Our findings strongly encourage further research, particularly in regions with small numbers of recorded species. This endeavor will undoubtedly lead to numerous novel discoveries and provide a better understanding of the true Heteroptera diversity in Turkey.
Bu çalışma Ankara Üniversitesi Yabancı Diller Yüksekokulu Almanca hazırlık sınıfı öğrencilerinin yazılı anlatımlarında yaptıkları yanlışların kaynaklarının yanlış çözümlemesi yöntemi uygulanarak tespit edilmesi ve böylece yazma eğitiminde iyileştirici uygulamaların belirlenmesi amacını taşıyan betimsel bir çalışmadır.
Bu çalışmada öğrencilerden iki öğretim yılı boyunca yazma dersinde belirli zaman aralıklarıyla yazılı dilde veriler alınmış, alınan bu veriler belirli başlıklar altında sınıflandırılıp yorumlanmıştır. Bu veriler toplanırken veya yıl boyunca devam eden yabancı dil öğrenme süresince ders işleme tekniği ve materyal bakımından araştırmacıların herhangi bir müdahalesi olmamıştır. Alınan verilerin hepsi öğrencinin kendi dil bilgisini yansıtmaktadır. Elde edilen veriler SPSS İstatiksel Analiz Programı ile değerlendirilerek, bulguların yüzdelik oranları ve yorumlanması yapılmıştır.
Elde edilen verilerin sonuçlarına göre, yanlışların genellikle ana dilden yapılan yanlış aktarımlardan kaynaklandığı tespit edilmiştir. Bu nedenle kaynağı kesin belli olan problemli noktaların yanlış çözümlemesi yoluyla çözümlenmesiyle tamamlayıcı öğretim ile iyileştirilmesi amaçlanmaktadır.
Das Ziel dieses Beitrags besteht darin, am Beispiel der türkischen Germanistikstudenten an der Ege Universität die Merkmale und Entwicklung der pragmatisch-diskursiven Fähigkeit als eine Teilkompetenz der fremdsprachlichen Gesprächskompetenz zu untersuchen. Die Arbeit gliedert sich in zwei Abschnitte: Der erste Teil befasst sich mit der ausführlichen Beschreibung der Gesprächskompetenz als fremdsprachliche Kompetenz im Deutschen als Fremdsprache, der Bewertung der fremdsprachlichen Gesprächskompetenz als sprachproduktive Leistung und der Vorstellung von Subkategorien der pragmatisch-diskursiven Fähigkeit anhand der Beispiele aus dem Arbeitskorpus. Im zweiten Teil wird das Untersuchungsdesign und die Analyseergebnisse ausführlich dargestellt.
This paper presents new data, characteristic features, standard body measurements and illustrations of the rare European linyphiid spider Glyphesis taoplesius Wunderlich, 1969; which is recorded here for the first time in Slovakia. The species was found with high abundance in pitfall traps exposed in a floodplain forest near a water reservoir in the lowland Podunajská rovina.
Language planning for the Irish language in the Republic of Ireland has featured prominently in international language policy and planning literature over the years. Researchers in the field may not be up to date, however, with recent developments in the area of Irish language planning and their impact on the language ecology. This monograph describes the language planning situation in the Republic of Ireland in its historical and social contexts as well as delineating language policy and planning for the Irish language implemented over the past number of years, showing developments in education, community, media, religion and local politics.
Dieser Beitrag verhandelt die poetische Bildlichkeit in Eichendorffs Märchennovelle "Die Zauberei im Herbste". Dabei werden verschiedene Ebenen der Bildlichkeit voneinander unterschieden. Zum einen die Ebene einer rhetorischen Bildlichkeit, die sich in dem erfüllt, was Theodor W. Adorno mit antiökonomische Entgrenzung umschrieben hat. Als "zweite Natur" eröffnet Eichendorffs Sprache eine Dimension des Sinnlichen, die sich aus der Gegenüberstellung stereotypisierter Bildelemente ergibt. Neben dieser rhetorischen Ebene lässt sich eine Ebene der bildlichen Textur ausmachen, die einmal zur bildererzeugenden Tätigkeit des Unbewussten der agierenden Personen ins Verhältnis gesetzt und schließlich in einem poetologischen Ausgriff auf die Selbstreflexivität romantischer Kunstproduktion bezogen wird.
Dieser Beitrag zu Goethes "Wahlverwandtschaften" geht von der Prämisse aus, dass dem Roman ein ausgeklügeltes System szenischer, bildlicher und narrativer Rahmungen zugrunde liegt. Im Mittelpunkt der Überlegungen stehen die Tableaux vivants, die als in Szene gesetzte Ein-Bildungen Umgruppierungen der auf der Handlungsebene entworfenen Konfigurationen von Handeln, Lieben und Wissen vornehmen. Der Fokus der Argumentation richtet sich auf die selbstreflexive Funktion dieser ‚lebenden Bilder’: in ihnen spiegelt und reflektiert sich der mediale Zuschnitt der Zeichen, aus denen sich die Begehrens- und Wissensordnungen des Romans konstituieren. Obwohl die Tableaux vivants den "erfüllten Augenblick" in der Stillstellung der Zeit zu verwirklichen vorgeben, überantworten sie diesen doch einer Repräsentationslogik der Mortifikation.
"Fürstin, wissen Sie, daß ich eine einzige Sehnsucht hätte: nach Toledo zu reisen. Diese Nacht bildete ich mir plötzlich ein, wir thätens, halb dachte ichs, halb träumte ichs und ließ mich in Beidem recht weit gehen".
In dieser Passage eines Briefes, den Rainer Maria Rilke am 27. September 1911 aus Paris an seine mütterliche Freundin und Mäzenin Marie von Thurn und Taxis schreibt, artikuliert sich ein Wunschtraum des Verfassers, der nicht nur bald schon in Erfüllung gehen sollte: seine imaginäre, ja visionäre Ausrichtung ist es vor allem, die Rilkes Spanienreise strukturell bestimmen wird.
Rilkes Sehnsucht nach Toledo, die Vision einer Stadt, deren Anblick Leben und Schaffen grundlegend zu ändern in der Lage sein könnte, geht auf seine intensive Beschäftigung mit Gemälden El Grecos zurück, welche schon lange vor seinem endgültigen Aufbruch nach Spanien einsetzt. Wenn nun Rilke schon vor seiner Reise aus seiner Bildbetrachtung Vorstellungen entwickelt, die er auf Spanien projiziert, heben sich im Blick des Betrachters die Unterscheidung von Kunst und Lebenswirklichkeit auf. Die spanische Landschaft konstituiert sich als Kunst-Landschaft erst im Akt des gestaltenden Sehens, welches vorgegebenen ikonographischen Mustern, hier solchen El Grecos, folgt. Jede Begegnung mit der Außenwelt wird dem Künstler dort zum deja-vu-Erlebnis, wo das Sichtbare eine spiegelbildliche Reproduktion seines imaginären Landschaftsentwurfs darstellt. Der vorliegende Beitrag will den poetologischen und wahrnehmungsästhetischen Implikationen einer solchen Betrachterperspektive nachgehen.
Seit Beginn der 2000er Jahre hat sich in den Kulturwissenschaften die so genannte Dingforschung etabliert, die nach dem Stellenwert materieller Güter und der Materialisierung von kulturellem Wissen fragt. Mit diesem methodischen Trend verbinden sich nähere Aufschlüsse über symbolische Prozesse kultureller Wissensgenerierung. Aber nicht nur die symbolische Funktion und Qualität von Dingen wurde diskutiert, sondern immer stärker deren pure materielle Existenz mit ihrer Wirkung auf soziale Kommunikation und Handlungsabläufe. Die Dingforschung erhielt im Wesentlichen von der Ethnologie Impulse, bis heute ist ein Boom an Publikationen über Dinge (des Alltags) zu verzeichnen. Auch für die Literaturwissenschaften gewann der Ding-Begriff an Popularität. Das Spektrum der Beschäftigung reicht von der literarischen Auseinandersetzung mit der Materialität von Dingen bis zu Reflexionen über ihren Gebrauchswert, von ihrer phänomenologischen Erscheinungsweise bis zu ihrer poetologischen Funktion in Texten. Der vorliegende Beitrag fragt nach der Valenz der in Texten von Adalbert Stifter, Francis Ponge und W.G. Sebald dargestellten und beschriebenen Dinge. Die drei genannten Autoren interessieren besonders, da sie eine offenkundige Aufmerksamkeit für kleine Dinge aufbringen und diese unabhängig von deren Gebrauchs- und Nützlichkeitswert aufwerten. Welche Rolle spielen hier alltägliche, nebensächliche Dinge? Übernehmen sie eine spezifische Bedeutung im Prozess kultureller Sinnstiftung? Eignet ihnen etwas Widerständiges, ein kritisches, vielleicht sogar ein erkenntnisleitendes Potenzial, sodass man sogar von einer Ethik kleiner Dinge sprechen könnte? Sind kleine Dinge dazu im Stande, herkömmliche Ordnungen des Verhältnisses von Mensch und Objektwelt und die damit verbundenen Implikationen von Macht und Verfügungsgewalt umzustülpen? Mit Adalbert Stifter, Francis Ponge und W.G. Sebald wird eine Konstellation gewählt, die auf den ersten Blick disparater nicht sein könnte und doch bei aller Unterschiedlichkeit Gemeinsamkeiten aufweist.
Aus den angestellten Untersuchungen dürften folgende allgemeine Schlüsse gezogen werden können: Der Hydrodiffusionskoeffizient steigt bei allen untersuchten Elektrolyten mit der Verdünnung von einer gewisssn Normalität an, ungleich für ungleiche Substanzen. Er steigt auch mit zunehmender Konzentration und wird daher ein Minimum durchlaufen, falls Bildungen von Molekülkomplexen bei höhern Konzentrationsgraden nicht den Diffusionsverlauf stören. Der Diffusionstemperaturkoeffizient hat ungleiche Werte für verschiedene Substanzen und ist gleich der Summe der Temperaturkoeffizienten des osmotischen Druckes und des elektrolytischen Leitvermögens. Nernsts Theorie und Formel für Berechnung der Koeffizienten bei unendlicher Verdünnung und Arrhenius´ Hypothese über den Gang der Diffusiollskurve bei Elektrolyten sind durch die Versuche bestätigt worden. Die innere Reibung f´ des Moleküls ist etwas kleiner als die Summe der Reibungen von dessen Ionen f, und das Verhältnis f´/f wird desto grösser, je höher das elektrolytische Leitvermögen des Salzes ist.
Adler ve Freud'un da işaret ettiği gibi babalar kızlarıyla, anneler de oğullarıyla iyi ilişkiler kurabilmektedir. Gerçek yaşamla ilgili bu saptama, çağdaş Alman yazarlarından Karl-Heinz Ott'un 1998 yılında yayımlanmış ve "Ins Offene" adını taşıyan romanının kurmaca dünyasında, bu sefer anne-oğul ilişkisi bazında, tersine işlemektedir.
Çalışmada, anne ve babanın birlikte yaşamamaları, yani aralarında evliliğin gerçekleşmemesi, anne ve oğlunun farklı karakterde olmaları, annenin oğluna olan aşırı bağımlılığı ve kırsal ataerkil toplum bu ilişkiyi sorunlu hale getiren ana etmenler olarak belirlenmiştir.
Önümüzdeki çalışma, Türkçe Çeviriler Bibliyografyası adlı çalışmada yer alan bilgiler ışığında Türkiye Cumhuriyeti’nin kuruluşundan 2016 yılına kadar Türkçeye çevrilmiş ve/ veya Türkiye’de yayımlanmış Alman edebi eserlerini raporlamayı amaçlamaktadır. Bu amaçla öncelikle, Türkçe Çeviriler Bibliyografyası kaynak kitabında da belirtildiği gibi çeşitli basılı ve elektronik kaynaklar (http://www.toplukatalog.gov.tr; https://kasif.mkutup.gov.tr ve http://koha.ekutuphane.gov.tr) taranarak bir veri tabanı oluşturulmuştur. Önümüzdeki çalışmada bu bilgilerden yola çıkılarak aşağıdaki soruların yanıtları aranmıştır: 1. Yıllara göre Almancadan Türkçeye çevrilen eserler belirlendiğinde karşımıza nasıl bir tablo çıkacaktır? 2. Her edebi türden toplam kaç kitap yayımlanmıştır? 3. En çok hangi yazarların eserleri Türkçeye çevrilmiştir? 4. Almancadan Türkçeye çevrilen eserler en çok hangi yayınevi tarafından basılmıştır? 5. En çok hangi çevirmenler Almancadan Türkçeye eserler kazandırmıştır? Bu soruların yanıtlarına istinaden niceliksel değerlere dayanan grafikler hazırlanmıştır. Daha sonra ise hazırlanan bu grafikler niteliksel olarak değerlendirilerek eserler Türkçeye çevrilirken hangi ölçütlerin esas alındığı, çeviri tercihlerinin- dönemine veya çevirmenine göre- nasıl yapıldığı tartışılmaktadır.
Çeviri faaliyeti, 18. yüzyılda Osmanlı Devleti'nin batılılaşması ve modernleşmesinde önemli bir yere sahipti. Bu amaca yönelik olarak çeviri eylemi, Osmanlı döneminde aydınlanma çağındaki fikirlerin yayılması ile birlikte siyasal ve bilimsel fikirlerin yerleşmesinde de çok etkili olmuştur. Bu durum Türkiye Cumhuriyeti'nin kuruluş yıllarında da devam etmiştir. Bu çeviri faaliyetini gerçekleştiren "gizli kahramanlar", yani çevirmenler, Türk diline ve edebiyatına yaptıkları katkılara nazaran pek tanınmazlar ve bilinmezler. Peki, bu çevirmenler kimlerdi? Kimlerin eserleri hangi dilden ve ne zaman çevrilip, hangi yayınevleri tarafından yayımlanmıştır? Türkçe Çevirmenler Sözlüğü'nde Türk edebiyatına katkıda bulunan ve Türk edebiyatının çeviri yoluyla zenginleşmesinde katkı sağlayan çevirmenlerin listelerini oluşturmak amaçlanmıştır. Ege Üniversitesi ile Johannes Gutenberg Üniversitesi Germersheim-Mainz (Almanya) mütercim tercümanlık bölümlerinin ortak yürüttükleri GIP (Germanistische Institutspartnerschaft) projesi bağlamında Türkçe Çeviriler Bibliyografyası kitap çalışması fikri de ortaya çıkmıştır. Uzun bir yöntem arayışından sonra başta Ege Üniversitesi Kütüphanesi, Hacettepe Üniversitesi Kütüphanesi, İstanbul Üniversitesi Kütüphanesi, Boğaziçi Üniversitesi Kütüphanesi ve Milli Kütüphane kayıtlarını barındıran ve T.C. Kültür ve Turizm Bakanlığı Kütüphaneler ve Yayımlar Genel Müdürlüğü ve TÜBİTAK ULAKBİM'in Ulusal Toplu Katalog veri tabanından yararlanılarak yabancı dilden Türkçeye aktarılan eserler ele alınmıştır. Çalışmada Cumhuriyetin ilk yıllarından 2016 yılına kadar Türkçeye aktarılan dil ve edebiyatların nesir, nazım ve tiyatro gibi edebi türlerine göre çevirileri incelenmiştir. Toplam 18.741 eser ve 6.006 çevirmen kaydına ulaşılmıştır.
Lexikalische Merkmale der türkischen Rechtssprache : am Beispiel des neuen Strafgesetzbuches (YTCK)
(2019)
Ziel dieser Studie ist es, die Besonderheiten von Rechtstexten in türkischer Sprache am Beispiel des neuen türkischen Strafgesetzbuches (YTCK) zu analysieren. In der Arbeit soll untersucht werden, inwieweit das YTCK vom alten türkischen Strafgesetzbuch von 1926 (ETCK) abweicht. Im Fokus des Forschungsinteresses steht die lexikalische Struktur des YTCK. Diese Studie erfordert einen interdisziplinär ausgerichteten Ansatz, der Rechts- und Sprachwissenschaften integriert. Der Schwerpunkt liegt auf der lexikalischen Analyse der Fachsprache des Rechts.
The methylene-tetrahydrofolate reductase (MTHFR) is a key enzyme in acetogenic CO2 fixation. The MetVF-type enzyme has been purified from four different species and the physiological electron donor was hypothesized to be reduced ferredoxin. We have purified the MTHFR from Clostridium ljungdahlii to apparent homogeneity. It is a dimer consisting of two of MetVF heterodimers, has 14.9 ± 0.2 mol iron per mol enzyme, 16.2 ± 1.0 mol acid-labile sulfur per mol enzyme, and contains 1.87 mol FMN per mol dimeric heterodimer. NADH and NADPH were not used as electron donor, but reduced ferredoxin was. Based on the published electron carrier specificities for Clostridium formicoaceticum, Thermoanaerobacter kivui, Eubacterium callanderi, and Clostridium aceticum, we provide evidence using metabolic models that reduced ferredoxin cannot be the physiological electron donor in vivo, since growth by acetogenesis from H2 + CO2 has a negative ATP yield. We discuss the possible basis for the discrepancy between in vitro and in vivo functions and present a model how the MetVF-type MTHFR can be incorporated into the metabolism, leading to a positive ATP yield. This model is also applicable to acetogenesis from other substrates and proves to be feasible also to the Ech-containing acetogen T. kivui as well as to methanol metabolism in E. callanderi.
Die am Ende des 19. Jahrhunderts in Frankreich entstandene Décadence hatte einen wichtigen Einfluss auf europäische Literaturen. Charles Baudelaire, Paul Bourget, Hermann Bahr und Friedrich Nietzsche sind unter den Vertretern dieser literarischen Bewegung aufzuzählen. Die Wirkung der Décadence auf derzeitige türkische Literatur ist aus vielen Werken erkennbar. Yakup Kadris frühe Werke tragen auch klare Spuren der 'Décadence'. In seinem Roman 'Yaban' – obwohl es ein realistischer Roman ist – sind viele dekadente Eigenschaften zu betrachten. Der große Abgrund zwischen den türkischen Intellektuellen und den Dörfern ist ein wichtiges Thema des Werkes. Der Protagonist Ahmet Celâl beschließt nach dem Ersten Weltkrieg in einem kleinen Dorf Anatoliens zu leben. Durch seine Erfahrungen und Beziehungen mit den Dörflern treten zahlreiche dekadente Eigenschaften der Dörfler und des Protagonisten in Vordergrund. Ahmet Celâl konfrontiert die Einsamkeit, Krankheiten, Hilflosigkeit, Entfremdung und allerart soziokulturellen Verfall im Dorf, was die dekadente Seite des Dorfes zeigt. Andererseits sind seine dekadenten Haltungen wie Zurückgezogenheit, Übertreibung der Hässlichkeit und Schönheit, Widrigkeit, Verschönerung des Todes und Pessimismus im Werk zu sehen. In dieser Arbeit wird eine kurze Information über die Dekadenz und deren Vertreter vermittelt. Anhand der Décadence-Auffassungen von Nietzsche, Bourget und Bahr werden dekadente Motive in Yakup Kadris Roman Yaban dargestellt.
Türkiye ile Almanya arasında siyasi, ekonomik, bilimsel, ticari, kültürel ve daha birçok alanda yoğun bir işbirliği söz konusudur. Ayrıca Almanya’da yaklaşık üç milyon Türkiye vatandaşı yaşamakta ve Türkiye'ye uzun yıllardır en fazla yabancı turist Almanya'dan gelmektedir. Bütün bu nedenlerden dolayı Almanca konuşabilmek Türkiye'de farklı sektörlerden birçok iş kolunda çalışanlarda aranan bir nitelik haline gelmiştir. Turizm bu sektörlerin başında gelmektedir. Turizm çalışanlarının ihtiyaçları doğrultusunda kurslarda, ilgili fakülte ve yüksekokullarda mesleki Almanca dersleri verilmektedir. Mesleki Almanca öğretimi için bilinen dil öğretim yöntemleri kullanılmakla birlikte, ilgili meslek kolunun gerektirdiği dilsel beceriler göz ününde bulundurularak farklı yöntem ve tekniklerden de yararlanılmaktadır. Bu çalışmada turizm mesleki dili tanımlanıp, örneklerle açıklanmış ve yabancı dil öğretim yöntemlerinin özellikleri açıklanarak, turizm için mesleki Almanca bilgi ve becerilerini kazandırmadaki yeterliliği üzerine bir tartışma yürütülmüştür. Çalışmada herhangi bir örneklem grubu üzerinde deney veya gözlem yapılmaksızın, konuyla ilgili yapılan çalışmalar, öğretmen ve öğrenci görüşleri dikkate alınmıştır.
Çeviri yaparken her iki dile, kültüre yeterince hâkim olmamak bir dizi çeviri hatalarına yol açabilir. Bu noktada kaynak ve erek dilde yeterli kelime hazinesine sahip olmanın yanı sıra kelimelerin kullanım alanlarını, kurallarını, edim bilimsel etkilerini, sözdizimsel kuralları vs. de iyi bilmek gerekir. Humboldt ve Saussure'ün dil hakkındaki düşüncelerinden etkilenen Trier'in ortaya attığı sözlüksel alan teorisinin metin anlama ve anlatma edinci kapsamında etkilerinin neler olabileceği ve çeviribilimin sözlüksel alan teorisinden nasıl yararlanabileceği konusu irdelenmeye çalışılacaktır.
Trier'e (1973:5) göre bir sözcüğün anlaşılabilmesi için, sözlüksel alanın tamamının bilinmesi gerekir ve ancak sözlüksel alana hâkim isek o sözcüğü doğru anlayabiliriz. Anlam sadece ve sadece sözlüksel alan sayesinde vardır. Sözlüksel alan yoksa anlam da yoktur. Anlatılmak istenen düşünceye veya olguya dair bir kelimenin belli bir dilde bulunmaması bu düşüncenin veya olgunun o dilde olmadığı anlamına gelmez. Hayata dair genel kültür bilgimize ve tecrübelerimize dayanarak bu yeni kavramı anlayabiliriz.
Çeviri yaparken her iki dile, kültüre yeterince hâkim olmamak bir dizi çeviri hatalarına yol açabilir. Bu noktada kaynak ve erek dilde yeterli kelime hazinesine sahip olmanın yanı sıra kelimelerin kullanım alanlarını, kurallarını, edim bilimsel etkilerini, sözdizimsel kuralları vs. de iyi bilmek gerekir. Humboldt ve Saussure’ün dil hakkındaki düşüncelerinden etkilenen Trier’in ortaya attığı sözlüksel alan teorisinin metin anlama ve anlatma edinci kapsamında etkilerinin neler olabileceği ve çeviribilimin sözlüksel alan teorisinden nasıl yararlanabileceği konusu irdelenmeye çalışılacaktır. Trier’e (1973:5) göre bir sözcüğün anlaşılabilmesi için, sözlüksel alanın tamamının bilinmesi
gerekir ve ancak sözlüksel alana hâkim isek o sözcüğü doğru anlayabiliriz. Anlam sadece ve sadece sözlüksel alan sayesinde vardır. Sözlüksel alan yoksa anlam da yoktur. Anlatılmak istenen düşünceye veya olguya dair bir kelimenin belli bir dilde bulunmaması bu düşüncenin veya olgunun o dilde olmadığı anlamına gelmez. Hayata dair genel kültür bilgimize ve tecrübelerimize dayanarak bu yeni kavramı
anlayabiliriz.