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Seven different instruments and measurement methods were used to examine the immersion freezing of bacterial ice nuclei from Snomax® (hereafter Snomax), a product containing ice active protein complexes from non-viable Pseudomonas syringae bacteria. The experimental conditions were kept as similar as possible for the different measurements. Of the participating instruments, some examined droplets which had been made from suspensions directly, and the others examined droplets activated on previously generated Snomax particles, with particle diameters of mostly a few hundred nanometers and up to a few micrometers in some cases. Data were obtained in the temperature range from −2 to −38 °C, and it was found that all ice active protein complexes were already activated above −12 °C. Droplets with different Snomax mass concentrations covering 10 orders of magnitude were examined. Some instruments had very short ice nucleation times down to below 1 s, while others had comparably slow cooling rates around 1 K min−1. Displaying data from the different instruments in terms of numbers of ice active protein complexes per dry mass of Snomax, nm, showed that within their uncertainty the data agree well with each other as well as to previously reported literature results. Two parameterizations were taken from literature for a direct comparison to our results, and these were a time dependent approach based on a contact angle distribution Niedermeier et al. (2014) and a modification of the parameterization presented in Hartmann et~al.~(2013) representing a time independent approach. The agreement between these and the measured data were good, i.e. they agreed within a temperature range of 0.6 K or equivalently a range in nm of a factor of 2. From the results presented herein, we propose that Snomax, at least when carefully shared and prepared, is a suitable material to test and compare different instruments for their accuracy of measuring immersion freezing.
Immersion freezing is the most relevant heterogeneous ice nucleation mechanism through which ice crystals are formed in mixed-phase clouds. In recent years, an increasing number of laboratory experiments utilizing a variety of instruments have examined immersion freezing activity of atmospherically relevant ice nucleating particles (INPs). However, an inter-comparison of these laboratory results is a difficult task because investigators have used different ice nucleation (IN) measurement methods to produce these results. A remaining challenge is to explore the sensitivity and accuracy of these techniques and to understand how the IN results are potentially influenced or biased by experimental parameters associated with these techniques.
Within the framework of INUIT (Ice Nucleation research UnIT), we distributed an illite rich sample (illite NX) as a representative surrogate for atmospheric mineral dust particles to investigators to perform immersion freezing experiments using different IN measurement methods and to obtain IN data as a function of particle concentration, temperature (T), cooling rate and nucleation time. Seventeen measurement methods were involved in the data inter-comparison. Experiments with seven instruments started with the test sample pre-suspended in water before cooling, while ten other instruments employed water vapor condensation onto dry-dispersed particles followed by immersion freezing. The resulting comprehensive immersion freezing dataset was evaluated using the ice nucleation active surface-site density (ns) to develop a representative ns(T) spectrum that spans a wide temperature range (−37 °C < T < −11 °C) and covers nine orders of magnitude in ns.
Our inter-comparison results revealed a discrepancy between suspension and dry-dispersed particle measurements for this mineral dust. While the agreement was good below ~ −26 °C, the ice nucleation activity, expressed in ns, was smaller for the wet suspended samples and higher for the dry-dispersed aerosol samples between about −26 and −18 °C. Only instruments making measurement techniques with wet suspended samples were able to measure ice nucleation above −18 °C. A possible explanation for the deviation between −26 and −18 °C is discussed. In general, the seventeen immersion freezing measurement techniques deviate, within the range of about 7 °C in terms of temperature, by three orders of magnitude with respect to ns. In addition, we show evidence that the immersion freezing efficiency (i.e., ns) of illite NX particles is relatively independent on droplet size, particle mass in suspension, particle size and cooling rate during freezing. A strong temperature-dependence and weak time- and size-dependence of immersion freezing efficiency of illite-rich clay mineral particles enabled the ns parameterization solely as a function of temperature. We also characterized the ns (T) spectra, and identified a section with a steep slope between −20 and −27 °C, where a large fraction of active sites of our test dust may trigger immersion freezing. This slope was followed by a region with a gentler slope at temperatures below −27 °C. A multiple exponential distribution fit is expressed as ns(T) = exp(23.82 × exp(−exp(0.16 × (T + 17.49))) + 1.39) based on the specific surface area and ns(T) = exp(25.75 × exp(−exp(0.13 × (T + 17.17))) + 3.34) based on the geometric area (ns and T in m−2 and °C, respectively). These new fits, constrained by using an identical reference samples, will help to compare IN measurement methods that are not included in the present study and, thereby, IN data from future IN instruments.
Serial quantification of BCR–ABL1 mRNA is an important therapeutic indicator in chronic myeloid leukaemia, but there is a substantial variation in results reported by different laboratories. To improve comparability, an internationally accepted plasmid certified reference material (CRM) was developed according to ISO Guide 34:2009. Fragments of BCR–ABL1 (e14a2 mRNA fusion), BCR and GUSB transcripts were amplified and cloned into pUC18 to yield plasmid pIRMM0099. Six different linearised plasmid solutions were produced with the following copy number concentrations, assigned by digital PCR, and expanded uncertainties: 1.08±0.13 × 106, 1.08±0.11 × 105, 1.03±0.10 × 104, 1.02±0.09 × 103, 1.04±0.10 × 102 and 10.0±1.5 copies/μl. The certification of the material for the number of specific DNA fragments per plasmid, copy number concentration of the plasmid solutions and the assessment of inter-unit heterogeneity and stability were performed according to ISO Guide 35:2006. Two suitability studies performed by 63 BCR–ABL1 testing laboratories demonstrated that this set of 6 plasmid CRMs can help to standardise a number of measured transcripts of e14a2 BCR–ABL1 and three control genes (ABL1, BCR and GUSB). The set of six plasmid CRMs is distributed worldwide by the Institute for Reference Materials and Measurements (Belgium) and its authorised distributors (https://ec.europa.eu/jrc/en/reference-materials/catalogue/; CRM code ERM-AD623a-f).
Myelodysplastic syndromes (MDSs) represent clonal disorders mainly of the elderly that are characterized by ineffective hematopoiesis and an increased risk of transformation into acute myeloid leukemia. The pathogenesis of MDS is thought to evolve from accumulation and selection of specific genetic or epigenetic events. Emerging evidence indicates that MDS is not solely a hematopoietic disease but rather affects the entire bone marrow microenvironment, including bone metabolism. Many of these cells, in particular mesenchymal stem and progenitor cells (MSPCs) and osteoblasts, express a number of adhesion molecules and secreted factors that regulate blood regeneration throughout life by contributing to hematopoietic stem and progenitor cell (HSPC) maintenance, self-renewal and differentiation. Several endocrine factors, such as erythropoietin, parathyroid hormone and estrogens, as well as deranged iron metabolism modulate these processes. Thus, interactions between MSPC and HSPC contribute to the pathogenesis of MDS and associated pathologies. A detailed understanding of these mechanisms may help to define novel targets for diagnosis and possibly therapy. In this review, we will discuss the scientific rationale of "osteohematology" as an emerging research field in MDS and outline clinical implications.
Background: In an earlier study we demonstrated the feasibility to create tissue engineered venous scaffolds in vitro and in vivo. In this study we investigated the use of tissue engineered constructs for ureteral replacement in a long term orthotopic minipig model. In many different projects well functional ureretal tissue was established using tissue engineering in animals with short-time follow up (12 weeks). Therefore urothelial cells were harvested from the bladder, cultured, expanded in vitro, labelled with fluorescence and seeded onto the autologous veins, which were harvested from animals during a second surgery. Three days after cell seeding the right ureter was replaced with the cell-seeded matrices in six animals, while further 6 animals received an unseeded vein for ureteral replacement. The animals were sacrificed 12, 24, and 48 weeks after implantation. Gross examination, intravenous pyelogram (IVP), H&E staining, Trichrome Masson's Staining, and immunohistochemistry with pancytokeratin AE1/AE3, smooth muscle alpha actin, and von Willebrand factor were performed in retrieved specimens.
Results: The IVP and gross examination demonstrated that no animals with tissue engineered ureters and all animals of the control group presented with hydronephrosis after 12 weeks. In the 24-week group, one tissue engineered and one unseeded vein revealed hydronephrosis. After 48 weeks all tissue engineered animals and none of the control group showed hydronephrosis on the treated side. Histochemistry and immunohistochemistry revealed a multilayer of urothelial cells attached to the seeded venous grafts.
Comclusions: Venous grafts may be a potential source for ureteral reconstruction. The results of so far published ureteral tissue engineering projects reveal data up to 12 weeks after implantation. Even if the animal numbers of this study are small, there is an increasing rate of hydronephrosis revealing failure of ureteral tissue engineering with autologous matrices in time points longer than 3 months after implantation. Further investigations have to prove adequate clinical outcome and appropriate functional long-term results.
In this study we show how size-resolved measurements of aerosol particles and cloud condensation nuclei (CCN) can be used to characterize the supersaturation of water vapor in a cloud. The method was developed and applied during the ACRIDICON-Zugspitze campaign (17 September to 4 October 2012) at the high-Alpine research station Schneefernerhaus (German Alps, 2650 m a.s.l.). Number size distributions of total and interstitial aerosol particles were measured with a scanning mobility particle sizer (SMPS), and size-resolved CCN efficiency spectra were recorded with a CCN counter system operated at different supersaturation levels.
During the evolution of a cloud, aerosol particles are exposed to different supersaturation levels. We outline and compare different estimates for the lower and upper bounds (Slow, Shigh) and the average value (Savg) of peak supersaturation encountered by the particles in the cloud. A major advantage of the derivation of Slow and Savg from size-resolved CCN efficiency spectra is that it does not require the specific knowledge or assumptions about aerosol hygroscopicity that are needed to derive estimates of Slow, Shigh, and Savg from aerosol size distribution data. For the investigated cloud event, we derived Slow ≈ 0.07–0.25%, Shigh ≈ 0.86–1.31% and Savg ≈ 0.42–0.68%.
The three-dimensional quantification of small scale processes in the upper troposphere and lower stratosphere is one of the challenges of current atmospheric research and requires the development of new measurement strategies. This work presents first results from the newly developed Gimballed Limb Observer for Radiance Imaging of the Atmosphere (GLORIA) obtained during the ESSenCe and TACTS/ESMVal aircraft campaigns. The focus of this work is on the so-called dynamics mode data characterized by a medium spectral and a very high spatial resolution. The retrieval strategy for the derivation of two- and three-dimensional constituent fields in the upper troposphere and lower stratosphere is presented. Uncertainties of the main retrieval targets (temperature, O3, HNO3 and CFC-12) and their spatial resolution are discussed. During ESSenCe, high resolution two-dimensional cross-sections have been obtained. Comparisons to collocated remote-sensing and in-situ data indicate a good agreement between the data sets. During TACTS/ESMVal a tomographic flight pattern to sense an intrusion of stratospheric air deep into the troposphere has been performed. This filament could be reconstructed with an unprecedented spatial resolution of better than 500 m vertically and 20 km × 20 km horizontally.
In the present work, three different techniques are used to separate ice-nucleating particles (INP) and ice particle residuals (IPR) from non-ice-active particles: the Ice Selective Inlet (ISI) and the Ice Counterflow Virtual Impactor (Ice-CVI), which sample ice particles from mixed phase clouds and allow for the analysis of the residuals, as well as the combination of the Fast Ice Nucleus Chamber (FINCH) and the Ice Nuclei Pumped Virtual Impactor (IN-PCVI), which provides ice-activating conditions to aerosol particles and extracts the activated ones for analysis. The collected particles were analyzed by scanning electron microscopy and energy-dispersive X-ray microanalysis to determine their size, chemical composition and mixing state. Samples were taken during January/February 2013 at the High Alpine Research Station Jungfraujoch. All INP/IPR-separating techniques had considerable abundances (median 20–70%) of contamination artifacts (ISI: Si-O spheres, probably calibration aerosol; Ice-CVI: Al-O particles; FINCH + IN-PCVI: steel particles). Also, potential measurement artifacts (soluble material) occurred (median abundance < 20%). After removal of the contamination particles, silicates and Ca-rich particles, carbonaceous material and metal oxides were the major INP/IPR particle types separated by all three techniques. Minor types include soot and Pb-bearing particles. Sea-salt and sulfates were identified by all three methods as INP/IPR. Lead was identified in less than 10% of the INP/IPR. It was mainly present as an internal mixture with other particle types, but also external lead-rich particles were found. Most samples showed a maximum of the INP/IPR size distribution at 400 nm geometric diameter. In a few cases, a second super-micron maximum was identified. Soot/carbonaceous material and metal oxides were present mainly in the submicron range. ISI and FINCH yielded silicates and Ca-rich particles mainly with diameters above 1 μm, while the Ice-CVI also sampled many submicron particles. Probably owing to the different meteorological conditions, the INP/IPR composition was highly variable on a sample to sample basis. Thus, some part of the discrepancies between the different techniques may result from the (unavoidable) non-parallel sampling. The observed differences of the particles group abundances as well as the mixing state of INP/IPR point to the need of further studies to better understand the influence of the separating techniques on the INP/IPR chemical composition.
Comparing two methods of determining infiltration rates of permeable interlocking concrete pavers
(2014)
Adequate infiltration through Permeable Interlocking Concrete Pavements (PICPs) is critical to their hydraulic performance. Detected by monitoring infiltration performance, reduced infiltration rates can indicate that maintenance is required. Measurement of infiltration rates has previously been problematic on PICPs because of a lack of accepted standard methodologies and the practical difficulties in modifying existing testing methodologies. On large sites, standard methodologies necessitate multiple measurements to achieve accuracy. Standard methods also contend with practical issues such as sealing the rings to the surface to prevent lateral water flow. This study examined the performance of two PICP surface infiltration rate measurement methods: a modified double-ring infiltrometer (DRIT), and a specially designed rainfall simulation infiltrometer (RSIT). A positive correlation (R2 = 0.85) of results was found between the two, demonstrating that the RSIT was comparable to the DRIT. The modified DRIT produced surface infiltration results approximately 60% higher than the RSIT results. The RSIT provided lower variation between tests, requiring fewer measurements in large sites whilst still maintaining accuracy, thereby improving testing efficiency. The new RSIT method also eliminates some of the practical difficulties with existing methodologies such as unrealistic pressure heads artificially increasing infiltration rates, and the use of sealant under test measurement infiltration rings.
Global warming, changes in the hydrological cycle and enhanced marine primary productivity all have been invoked to have contributed to the occurrence of widespread ocean anoxia during the Cenomanian-Turonian Oceanic Anoxic Event (OAE2; ~ 94 Ma), but disentangling these factors on a regional scale has remained problematic. We generated palynological and organic geochemical records that allow the separation of these forcing factors in a core spanning the OAE2 from Wunstorf, Lower Saxony Basin (LSB; North Gemany), which exhibits cyclic black shale–marl alternations related to the orbital precession cycle.
Despite the widely varying depositional conditions complicating the interpretation of the obtained records, TEX86H indicates that sea-surface temperature (SST) evolution in the LSB during OAE2 resembles that of previously studied sites throughout the proto-North Atlantic. Cooling during the so-called Plenus Cold Event interrupted black shale deposition during the early stages of OAE2. However, TEX86 does not vary significantly across marl–black shale alternations, suggesting that temperature variations did not force the formation of the cyclic black shale horizons. Relative (i.e., with respect to marine palynomorphs) and absolute abundances of pollen and spores are elevated during phases of black shale deposition, indicative of enhanced precipitation and run-off. High abundances of cysts from inferred heterotrophic and euryhaline dinoflagellates supports high run-off, which likely introduced additional nutrients to the epicontinental shelf resulting in elevated marine primary productivity.
We conclude that orbitally-forced enhanced precipitation and run-off, in tandem with elevated marine primary productivity, were critical in cyclic black shale formation on the northwest European epicontinental shelf and potentially for other OAE2 sections in the proto-Atlantic and Western Interior Seaway at similar latitudes as well.
The forest, savanna, and grassland biomes, and the transitions between them, are expected to undergo major changes in the future, due to global climate change. Dynamic Global Vegetation Models (DGVMs) are very useful to understand vegetation dynamics under present climate, and to predict its changes under future conditions. However, several DGVMs display high uncertainty in predicting vegetation in tropical areas. Here we perform a comparative analysis of three different DGVMs (JSBACH, LPJ-GUESS-SPITFIRE and aDGVM) with regard to their representation of the ecological mechanisms and feedbacks that determine the forest, savanna and grassland biomes, in an attempt to bridge the knowledge gap between ecology and global modelling. Model outcomes, obtained including different mechanisms, are compared to observed tree cover along a mean annual precipitation gradient in Africa. Through these comparisons, and by drawing on the large number of recent studies that have delivered new insights into the ecology of tropical ecosystems in general, and of savannas in particular, we identify two main mechanisms that need an improved representation in the DGVMs. The first mechanism includes water limitation to tree growth, and tree-grass competition for water, which are key factors in determining savanna presence in arid and semi-arid areas. The second is a grass-fire feedback, which maintains both forest and savanna occurrences in mesic areas. Grasses constitute the majority of the fuel load, and at the same time benefit from the openness of the landscape after fires, since they recover faster than trees. Additionally, these two mechanisms are better represented when the models also include tree life stages (adults and seedlings), and distinguish between fire-prone and shade-tolerant savanna trees, and fire-resistant and shade-intolerant forest trees. Including these basic elements could improve the predictive ability of the DGVMs, not only under current climate conditions but also and especially under future scenarios.
The Tarim River Basin, located in Xinjiang, NW China, is the largest endorheic river basin of China and one of the largest in whole Central Asia. Due to the extremely arid climate with an annual precipitation of less than 100 mm, the water supply along the Aksu and Tarim River solely depends on river water. This applies for anthropogenic activities (e.g. agriculture) as well as for the natural ecosystems so that both compete for water. The on-going increase of water consumption by agriculture and other human activities in this region has been enhancing the competition for water between human needs and nature. Against this background, 11 German and 6 Chinese universities and research institutes formed the consortium SuMaRiO (www.sumario.de), which aims at gaining a holistic picture of the availability of water resources in the Tarim River Basin and the impacts on anthropogenic activities and natural ecosystems caused by the water distribution within the Tarim River Basin. The discharge of the Aksu River, which is the major tributary to the Tarim, has been increasing over the past 6 decades due to enhanced glacier melt. Alone from 1989 to 2011, the area under agriculture more than doubled. Thereby, cotton became the major crop and there was a shift from small-scale farming to large-scale intensive farming. The major natural ecosystems along the Aksu and Tarim River are riparian ecosystems: Riparian (Tugai) forests, shrub vegetation, reed beds, and other grassland. Within the SuMaRiO Cluster the focus was laid on the Tugai forests, with Populus euphratica as dominant tree, because the most productive and species-rich natural ecosystems can be found among those forests. On sites with groundwater distance of less than 7.5 m the annual increments correlated with river runoffs of the previous year. But, the further downstream along the Tarim River, the more the natural river dynamics ceased, which impacts on the recruitment of Populus euphratica. Household surveys revealed that there is a considerable willingness to pay for conservation of those riparian forests with the mitigation of dust and sandstorms considered as the most important ecosystem service. This interdisciplinary project will result in a decision support tool (DST), build on the participation of regional stakeholders and models based on results and field experiments. This DST finally shall assist stakeholders in balancing the water competition acknowledging the major external effects of any water allocation.
Ein "hundertjähriger Krieg"? : über die Bildung einer Friedenskultur aus dem Geist des Krieges
(2014)
Wer nicht direkt Zeitgenosse im Jahre 1914 gewesen ist, kommt [...] nicht ohne Konstrukte und Nacherzählungen aus. Aber nicht nur das: Auch wer Zeitgenosse gewesen ist, mag die späteren Generationen mit Formen von Distanzierung überraschen, wie etwa Kafka mit seiner Tagebucheintragung vom 1. August 1914: "Deutschland hat Russland den Krieg erklärt. Nachmittag Schwimmschule" [...]. Nun wissen wir auch, dass Kafkas Werk einer "furchtbaren Welt" entspricht, indem sie "strukturell der Wirklichkeit, die wir zu erleben gezwungen wurden, unheimlich adäquat ist" [...]. Einer formneutralen Aufzeichnung wie derjenigen Kafkas bräuchte prinzipiell kein weiterer bedeutungsschwerer Charakter beigemessen zu werden. Jedoch könnte eine solche Aufzeichnung auch auf die Dynamik einer Kriegs- bzw. Friedenskultur hindeuten. Diese Dynamik hat nach der hier verfolgten Perspektive einen strukturellen Zusammenhang beider Kulturmuster als Spielarten, die allzu oft nur als Polaritäten, dementsprechend als Kontraste, angesehen werden. [...] Die hier vorgenommene Analyse einer solchen Problematik beinhaltet drei Schritte: 1. Die Auffächerung von Krieg und Frieden als Momente im unvollendeten Prozess der Zivilisation; 2. Thomas Manns retrospektiver Blick auf Kontraste und Spielarten, und 3. Jenseits von "kaltem Krieg", "heißem Frieden" und "blauäugigem" Pazifismus: "Ich will verstehen" oder die Rolle der Zwischenräume.
Der vorliegende Beitrag geht von der Fiktionalisierung des Ersten Weltkrieges in Remarques Erfolgsroman "Im Westen nichts Neues" (1929) aus und erforscht die literarische Funktionalisierung der Kriegsrepräsentation für Friedensdiskurse. "Zeit zu leben und Zeit zu sterben" (1954) enthält pazifistische Indizien, so dass Remarques Poetik des Friedens um die Darstellung der beiden Weltkriege strukturiert ist. In seinem Werk "Der seltsame Krieg" (2000) artikuliert der österreichische Schriftsteller Martin Auer seine Fiktion des Krieges um eine globale Sehnsucht nach Frieden, die auch neue Kriegsformen einschließt. So erhält der Signifikant "Krieg" eine dynamische Sinndeutung in der Konstruktion des Friedensdiskurses. Der Beitrag analysiert die klassischen Repräsentationen des Krieges und erkundet die Grundrisse einer Poetik des Friedens bei Erich Maria Remarque und Martin Auer.
In den Jahren 1912-1914 gelang es dem Deutschen Botschafter Karl Max Lichnowsky (1860-1928) und seiner Gattin, der Schriftstellerin Mechtilde Lichnowsky (1879-1958), die Botschafter-Residenz Carlton House Terrace zu einem Mittelpunkt des damaligen Londoner Kulturlebens und der Avantgarde zu verwandeln. Mechtilde Lichnowsky hatte mit ihrem ersten Buch "Götter, Könige und Tiere in Ägypten" (1913) einiges Aufsehen erregt und arbeitete in der Botschaft an ihrem zweiten Manuskript, dem Drama "Das Spiel mit dem Tod" (1915). Sie war eng mit Roger Fry befreundet und arbeitete in der britischen Avantgarde-Bewegung mit. Karl Max Lichnowsky bemühte sich bis zuletzt, den Krieg auf diplomatischem Wege zu verhindern. Die Mission der beiden Kosmopoliten scheiterte.
Ähnlich wie in anderen Krieg führenden Ländern war gerade die großstädtische Bevölkerung von Kriegseuphorie und einer spontanen Bereitschaft getragen, sich in den Dienst des Kriegs zu stellen. Das bald auch im Krieg florierende Unterhaltungstheater der meisten europäischen Metropolen zeigte geradezu mustergültig diese patriotisch-affirmative Tendenz. Doch in einem Land wie Portugal, in dem wenige Jahre zuvor durch eine vom städtischen liberalen Bürgertum getragene Revolution eine laizistische Republik nach französischem Vorbild installiert wurde, die noch einigermaßen instabil war, folgte die Unterhaltungskultur nicht dieser Art von patriotischer Gleichschaltung sondern bewahrte sich durchaus – besonders im Genre der Revue – satirische und kritische Eigenheiten.
Um Wedekinds politisches Engagement und Denken am Vorabend und während des Ersten Weltkriegs zu verstehen, bedarf es zunächst einer Rückschau, denn so sehr auch individuelle politische Äußerungen sich auf ein aktuelles Tagesgeschehen beziehen, sind sie doch nicht nur allein aus diesem Kontext heraus zu verstehen.
Zu Beginn noch Treffpunkt ausziehender Soldaten, die besonders in den ersten Monaten umjubelt die Städte verließen, wurde der Heimtransport Verwundeter besonders in den Grenzregionen mit zunehmender Dauer alltäglicher. Spätestens mit Kriegsende aber wird die Figur des Kriegsheimkehrers auch in den von der Westfront entfernten Städten wie Hamburg oder Berlin immer präsenter — als körperlich invalider Krüppel, wie auch als äußerlich unverletzter, aber tief traumatisierter Veteran.
Die Arbeit an "Ginster" fällt in die Jahre, in denen Kracauer für die Frankfurter Zeitung arbeitete. Im dortigen Feuilletonteil wurde der Roman 1928 erstmals veröffentlicht. Zugleich ist es jedoch auch eine Zeit, in der auf dem Büchermarkt eine regelrechte Flut von Literatur einsetzt, die sich mit dem Ersten Weltkrieg befasst.
Einen kleinen Ausschnitt der literarisch-künstlerischen Auseinandersetzung mit dem Weltkrieg möchte ich im Folgenden verfolgen, indem ich nachzeichne, wie sich der Erste Weltkriegs in drei Romane einschreibt, die man mit guten Argumenten als zentrale Texte der deutschsprachigen Literatur der Zwischenkriegszeit betrachten kann, sowohl thematisch als auch ästhetisch und programmatisch.
"Welch schamlose Bestie der Krieg ist" : zu Leben und Werk des Schriftstellers Alexander Moritz Frey
(2014)
Der vorliegende Beitrag verfolgt zwei Ziele: Zunächst gewährt eine überblicksartige Zusammenfassung von Freys Vita und seinen autobiografischen Stellungnahmen einen Einblick in seine Bekanntschaft mit Adolf Hitler aus der Zeit des Ersten Weltkriegs und die Gründe für seine Flucht aus Nazi-Deutschland. In einem zweiten, analytischen Teil wird eine Auswahl von Freys Antikriegstexten auf wiederkehrende semantische Relationen hin untersucht, die Aufschluss über das Erzählen vom Krieg geben.
Der Aufsatz beschäftigt sich mit den bisher von der Forschung kaum wahrgenommenen Kriegsschilderungen in E. G. Kolbenheyers Paracelsus-Trilogie (1917-1925), die, historische Analogien nutzend, einen bemerkenswert ambivalenten Blick auf den Ersten Weltkrieg wirft. Dabei beleuchtet sie Kriegseuphorie und mystische Momente des soldatischen Kampferlebnisses ebenso wie die verheerenden gesellschaftlichen Auswirkungen des Totalen Krieges. Ob sie aufgrund dieser, auch auf der Ebene der Darstellung nachweisbaren Vielschichtigkeit noch als antimodern zu bezeichnen ist, soll im Verlauf des Aufsatzes kontextualisierend geklärt werden.
The link between atmospheric radicals and newly formed particles at a spruce forest site in Germany
(2014)
It has been claimed for more than a century that atmospheric new particle formation is primarily influenced by the presence of sulfuric acid. However, the activation process of sulfuric acid related clusters into detectable particles is still an unresolved topic. In this study we focus on the PARADE campaign measurements conducted during August/September 2011 at Mt Kleiner Feldberg in central Germany. During this campaign a set of radicals, organic and inorganic compounds and oxidants and aerosol properties were measured or calculated. We compared a range of organic and inorganic nucleation theories, evaluating their ability to simulate measured particle formation rates at 3 nm in diameter (J3) for a variety of different conditions. Nucleation mechanisms involving only sulfuric acid tentatively captured the observed noon-time daily maximum in J3, but displayed an increasing difference to J3 measurements during the rest of the diurnal cycle. Including large organic radicals, i.e. organic peroxy radicals (RO2) deriving from monoterpenes and their oxidation products, in the nucleation mechanism improved the correlation between observed and simulated J3. This supports a recently proposed empirical relationship for new particle formation that has been used in global models. However, the best match between theory and measurements for the site of interest was found for an activation process based on large organic peroxy radicals and stabilised Criegee intermediates (sCI). This novel laboratory-derived algorithm simulated the daily pattern and intensity of J3 observed in the ambient data. In this algorithm organic derived radicals are involved in activation and growth and link the formation rate of smallest aerosol particles with OH during daytime and NO3 during night-time. Because the RO2 lifetime is controlled by HO2 and NO we conclude that peroxy radicals and NO seem to play an important role for ambient radical chemistry not only with respect to oxidation capacity but also for the activation process of new particle formation. This is supposed to have significant impact of atmospheric radical species on aerosol chemistry and should be taken into account when studying the impact of new particles in climate feedback cycles.
We present the application of Time-of-Flight Mass Spectrometry (TOF MS) for the analysis of halocarbons in the atmosphere, after cryogenic sample preconcentration and gas chromatographic separation. For the described field of application, the Quadrupole Mass Spectrometer (QP MS) is the state-of-the-art detector. This work aims at comparing two commercially available instruments, a QP MS and a TOF MS with respect to mass resolution, mass accuracy, sensitivity, measurement precision and detector linearity. Both mass spectrometers are operated on the same gas chromatographic system by splitting the column effluent to both detectors. The QP MS had to be operated in optimised Single Ion Monitoring (SIM) mode to achieve a sensitivity which could compete with the TOF MS. The TOF MS provided full mass range information in any acquired mass spectrum without losing sensitivity. Whilst the QP MS showed the performance already achieved in earlier tests, the sensitivity of the TOF MS was on average higher than that of the QP MS in the "operational" SIM mode by a factor of up to 3 reaching detection limits of less than 0.2 pg. Measurement precision determined for the whole analytical system was up to 0.2% depending on substance and sampled volume. The TOF MS instrument used for this study displayed significant non-linearities of up to 10% for two third of all analysed substances.
Ongoing and predicted global change makes understanding and predicting species’ range shifts an urgent scientific priority. Here, we provide a synthetic perspective on the so far poorly understood effects of interspecific interactions on range expansion rates. We present theoretical foundations for how interspecific interactions may modulate range expansion rates, consider examples from empirical studies of biological invasions and natural range expansions as well as process-based simulations, and discuss how interspecific interactions can be more broadly represented in process-based, spatiotemporally explicit range forecasts. Theory tells us that interspecific interactions affect expansion rates via alteration of local population growth rates and spatial displacement rates, but also via effects on other demographic parameters. The best empirical evidence for interspecific effects on expansion rates comes from studies of biological invasions. Notably, invasion studies indicate that competitive dominance and release from specialized enemies can enhance expansion rates. Studies of natural range expansions especially point to the potential for competition from resident species to reduce expansion rates. Overall, it is clear that interspecific interactions may have important consequences for range dynamics, but also that their effects have received too little attention to robustly generalize on their importance. We then discuss how interspecific interactions effects can be more widely incorporated in dynamic modeling of range expansions. Importantly, models must describe spatiotemporal variation in both local population dynamics and dispersal. Finally, we derive the following guidelines for when it is particularly important to explicitly represent interspecific interactions in dynamic range expansion forecasts: if most interacting species show correlated spatial or temporal trends in their effects on the target species, if the number of interacting species is low, and if the abundance of one or more strongly interacting species is not closely linked to the abundance of the target species.
Channelrhodopsin-2 (ChR2) is a cation-selective light-gated channel from Chlamydomonas reinhardtii (Nagel G, Szellas T, Huhn W, Kateriya S, Adeishvili N, Berthold P, et al. Channelrhodopsin-2, a directly light-gated cation-selective membrane channel. Proc Natl Acad Sci USA 2003;100:13940-5), which has become a powerful tool in optogenetics. Two-dimensional crystals of the slow photocycling C128T ChR2 mutant were exposed to 473 nm light and rapidly frozen to trap the open state. Projection difference maps at 6Å resolution show the location, extent and direction of light-induced conformational changes in ChR2 during the transition from the closed state to the ion-conducting open state. Difference peaks indicate that transmembrane helices (TMHs) TMH2, TMH6 and TMH7 reorient or rearrange during the photocycle. No major differences were found near TMH3 and TMH4 at the dimer interface. While conformational changes in TMH6 and TMH7 are known from other microbial-type rhodopsins, our results indicate that TMH2 has a key role in light-induced channel opening and closing in ChR2.
Translation fidelity and efficiency require multiple ribosomal (r)RNA modifications that are mostly mediated by small nucleolar (sno)RNPs during ribosome production. Overlapping basepairing of snoRNAs with pre-rRNAs often necessitates sequential and efficient association and dissociation of the snoRNPs, however, how such hierarchy is established has remained unknown so far. Here, we identify several late-acting snoRNAs that bind pre-40S particles in human cells and show that their association and function in pre-40S complexes is regulated by the RNA helicase DDX21. We map DDX21 crosslinking sites on pre-rRNAs and show their overlap with the basepairing sites of the affected snoRNAs. While DDX21 activity is required for recruitment of the late-acting snoRNAs SNORD56 and SNORD68, earlier snoRNAs are not affected by DDX21 depletion. Together, these observations provide an understanding of the timing and ordered hierarchy of snoRNP action in pre-40S maturation and reveal a novel mode of regulation of snoRNP function by an RNA helicase in human cells.
Global warming, changes in the hydrological cycle and enhanced marine primary productivity all have been invoked to have contributed to the occurrence of widespread ocean anoxia during the Cenomanian-Turonian Oceanic Anoxic Event (OAE2; ~ 94 Ma), but disentangling these factors on a regional scale has remained problematic. We generated palynological and organic geochemical records that allow the separation of these forcing factors in a core spanning the OAE2 from Wunstorf, Lower Saxony Basin (LSB; North Gemany), which exhibits cyclic black shale–marl alternations related to the orbital precession cycle.
Despite the widely varying depositional conditions complicating the interpretation of the obtained records, TEX86H indicates that sea-surface temperature (SST) evolution in the LSB during OAE2 resembles that of previously studied sites throughout the proto-North Atlantic. Cooling during the so-called Plenus Cold Event interrupted black shale deposition during the early stages of OAE2. However, TEX86 does not vary significantly across marl–black shale alternations, suggesting that temperature variations did not force the formation of the cyclic black shale horizons. Relative (i.e., with respect to marine palynomorphs) and absolute abundances of pollen and spores are elevated during phases of black shale deposition, indicative of enhanced precipitation and run-off. High abundances of cysts from inferred heterotrophic and euryhaline dinoflagellates supports high run-off, which likely introduced additional nutrients to the epicontinental shelf resulting in elevated marine primary productivity.
We conclude that orbitally-forced enhanced precipitation and run-off, in tandem with elevated marine primary productivity, were critical in cyclic black shale formation on the northwest European epicontinental shelf and potentially for other OAE2 sections in the proto-Atlantic and Western Interior Seaway at similar latitudes as well.
One of the most challenging aspects of RT-qPCR data analysis is the identification of reliable reference genes. Ideally, they should be neither induced nor repressed under different experimental conditions. To date, few reference genes have been adequately studied for sugarcane (Saccharum spp.) using statistical approaches. In this work, six candidate genes (αTUB, GAPDH, H1, SAMDC, UBQ, and 25S rRNA) were tested for gene expression normalization of sugarcane root tissues from drought-tolerant and -sensitive accessions after continuous dehydration (24 h). By undergoing different approaches (GeNorm, NormFinder, and BestKeeper), it was shown that most of them could be used in combinations for normalization purposes, with the exception of SAMDC. Nevertheless three of them (H1, αTUB, and GAPDH) were considered the most reliable reference genes. Their suitability as reference genes validated the expression profiles of two targets (AS and PFPα1), related to SuperSAGE unitags, in agreement with results revealed by previous in silico analysis. The other two sugarcane unitags (ACC oxidase and PIP1-1), after salt stress (100 mM NaCl), presented their expressions validated in the same way. In conclusion, these reference genes will be useful for dissecting gene expression in sugarcane roots under abiotic stress, especially in transcriptomic studies using SuperSAGE or RNAseq approaches.
Atherosclerosis is a chronic inflammatory disease. Lesion progression is primarily mediated by cells of the monocyte/macrophage lineage. IL-17A is a proinflammatory cytokine, which modulates immune cell trafficking and is involved inflammation in (auto)immune and infectious diseases. But the role of IL-17A still remains controversial. In the current study, we investigated effects of IL-17A on advanced murine and human atherosclerosis, the common disease phenotype in clinical care. The 26-wk-old apolipoprotein E–deficient mice were fed a standard chow diet and treated either with IL-17A mAb (n = 15) or irrelevant Ig (n = 10) for 16 wk. Furthermore, essential mechanisms of IL-17A in atherogenesis were studied in vitro. Inhibition of IL-17A markedly prevented atherosclerotic lesion progression (p = 0.001) by reducing inflammatory burden and cellular infiltration (p = 0.01) and improved lesion stability (p = 0.01). In vitro experiments showed that IL-17A plays a role in chemoattractance, monocyte adhesion, and sensitization of APCs toward pathogen-derived TLR4 ligands. Also, IL-17A induced a unique transcriptome pattern in monocyte-derived macrophages distinct from known macrophage types. Stimulation of human carotid plaque tissue ex vivo with IL-17A induced a proinflammatory milieu and upregulation of molecules expressed by the IL-17A–induced macrophage subtype. In this study, we show that functional blockade of IL-17A prevents atherosclerotic lesion progression and induces plaque stabilization in advanced lesions in apolipoprotein E–deficient mice. The underlying mechanisms involve reduced inflammation and distinct effects of IL-17A on monocyte/macrophage lineage. In addition, translational experiments underline the relevance for the human system.
Sudden cardiac death (SCD) remains a daunting problem. It is a major public health issue for several reasons: from its prevalence (20% of total mortality in the industrialized world) to the devastating psycho-social impact on society and on the families of victims often still in their prime, and it represents a challenge for medicine, and especially for cardiology. This text summarizes the discussions and opinions of a group of investigators with a long-standing interest in this field. We addressed the occurrence of SCD in individuals apparently healthy, in patients with heart disease and mild or severe cardiac dysfunction, and in those with genetically based arrhythmic diseases. Recognizing the need for more accurate registries of the global and regional distribution of SCD in these different categories, we focused on the assessment of risk for SCD in these four groups, looking at the significance of alterations in cardiac function, of signs of electrical instability identified by ECG abnormalities or by autonomic tests, and of the progressive impact of genetic screening. Special attention was given to the identification of areas of research more or less likely to provide useful information, and thereby more or less suitable for the investment of time and of research funds.
Ursine bears are a mammalian subfamily that comprises six morphologically and ecologically distinct extant species. Previous phylogenetic analyses of concatenated nuclear genes could not resolve all relationships among bears, and appeared to conflict with the mitochondrial phylogeny. Evolutionary processes such as incomplete lineage sorting and introgression can cause gene tree discordance and complicate phylogenetic inferences, but are not accounted for in phylogenetic analyses of concatenated data. We generated a high-resolution data set of autosomal introns from several individuals per species and of Y-chromosomal markers. Incorporating intraspecific variability in coalescence-based phylogenetic and gene flow estimation approaches, we traced the genealogical history of individual alleles. Considerable heterogeneity among nuclear loci and discordance between nuclear and mitochondrial phylogenies were found. A species tree with divergence time estimates indicated that ursine bears diversified within less than 2 My. Consistent with a complex branching order within a clade of Asian bear species, we identified unidirectional gene flow from Asian black into sloth bears. Moreover, gene flow detected from brown into American black bears can explain the conflicting placement of the American black bear in mitochondrial and nuclear phylogenies. These results highlight that both incomplete lineage sorting and introgression are prominent evolutionary forces even on time scales up to several million years. Complex evolutionary patterns are not adequately captured by strictly bifurcating models, and can only be fully understood when analyzing multiple independently inherited loci in a coalescence framework. Phylogenetic incongruence among gene trees hence needs to be recognized as a biologically meaningful signal.
Donald Siegel's 1971 film entitled "The Beguiled" is compared to Tale 1 of Day 3 from Giovanni Boccaccio’s "The Decameron". Both stories are about a man who arrives in a garden setting and finds nine sexually starved women. In Boccaccio's tale, a male gardener finds himself in a convent occupied by nine nuns with whom he proceeds to have sexual relations to everyone's satisfaction. Siegel's film is about a wounded soldier taken in at a girls' finishing school whose nine female residents become the objects of the hero's amorous attention. While Boccaccio adopts a philogynist tone with respect to the material, "The Beguiled" appears to be a virulently misogynist film projecting its female characters as jealous demons who end up mutilating and then killing their male suitor. Findings from evolutionary psychology pertaining to female jealousy and reproductive strategies are used to consider the respective attitudes toward women in the medieval tale and the twentieth-century film. Conclusions are drawn about the difficulty of placing either of the stories within a clear-cut philogynist or misogynist category.
Es wird die Entwicklung der Brockenvegetation von 1993 bis 2013 aufgezeigt. Von besonderem Interesse ist dabei die Vegetationsentwicklung auf ehemals versiegelten und später renaturierten Flächen. Aber auch den acidiphilen Zwergstrauchheiden galt ein besonderes Augenmerk, da diese bevorzugte Standorte für die Brockenanemone (Pulsatilla alpina ssp. alba) sind.
Über die seit dem Altertum übliche Verwendung der Knollen von Orchis morio und verwandter Arten (Salep) wird aus kulturhistorischer Sicht berichtet. Dabei wird auf die Gewinnung von Salep und seine Bedeutung als Aphrodisiakum, als pharmazeutische Droge und technisches Hilfsmittel eingegangen. Es folgen Ausführungen zur Bestandssituation von Orchis morio im Altmarkreis Salzwedel.
In the article the state of forming of communicative competence of future lawyers in higher education of Ukraine and Germany is analyzed. There is made the comparative description of preparation of the students of law faculty with an accent on forming of communicative competence on the example of the University of modern knowledge (Ukraine) and Frankfort university is named after Goethe (Germany).
It is drawn the conclusion, that the structure of professional preparation of future lawyers is folded educational and cognitive, research constituents, and also productive practice. A main place is taken to conception of communicative preparation of the future lawyers, the essence of it consists in integration of the special courses of the special and professional disciplines, in continuous perfection of skills of the verbal and writing broadcasting, receptions of analytical mental work, that need knowledge. It is also outlined the aim of productive practice of future lawyers in Ukraine that begins from the second course: the forming of professional abilities and skills of acceptance of independent decisions; the education of necessity systematic to proceed the knowledge, to promote a legal culture and professional legal consciousness; to teach to apply knowledge in practical activity. In Germany the practice for future lawyers begins from the first course and lasts two years in legal establishments (from civil cases, court from criminal cases or office of public prosecutor, administrative and managerial establishments, advocacy). The sign line of studies is an active collaboration with the faculties of law of the foreign states. All these factors assist the forming of communicative competence of lawyers.
We show that, under in vitro conditions, the vulnerability of astroglia to hypoxia is reflected by alterations in endothelin (ET)-1 release and capacity of erythropoietin (EPO) to regulate ET-1 levels. Exposure of cells to 24 h hypoxia did not induce changes in ET-1 release, while 48–72 h hypoxia resulted in increase of ET-1 release from astrocytes that could be abolished by EPO. The endothelin receptor type A (ETA) antagonist BQ123 increased extracellular levels of ET-1 in human fetal astroglial cell line (SV-FHAS). The survival and proliferation of rat primary astrocytes, neural precursors, and neurons upon hypoxic conditions were increased upon administration of BQ123. Hypoxic injury and aging affected the interaction between the EPO and ET systems. Under hypoxia EPO decreased ET-1 release from astrocytes, while ETA receptor blockade enhanced the expression of EPO mRNA and EPO receptor in culture-aged rat astroglia. The blockade of ETA receptor can increase the availability of ET-1 to the ETB receptor and can potentiate the neuroprotective effects of EPO. Thus, the new therapeutic use of combined administration of EPO and ETA receptor antagonists during hypoxia-associated neurodegenerative disorders of the central nervous system (CNS) can be suggested.
We enlarge the so-called extended linear Sigma model (eLSM) by including the charm quark according to the global U(4)r × U(4)l chiral symmetry. In the eLSM, besides scalar and pseudoscalar mesons, also vector and axial-vector mesons are present. Almost all the parameters of the model were fixed in a previous study of mesons below 2 GeV. In the extension to the four-flavor case, only three additional parameters (all of them related to the bare mass of the charm quark) appear.We compute the (OZI dominant) strong decays of open charmed mesons. The results are compatible with the experimental data, although the theoretical uncertainties are still large.
The Sahel has been the focus of scientific interest in environmental-human dynamics and interactions. The objective of the present study is to contribute to the recent debate on the re-greening of Sahel. The paper examines the dynamics of barren land in the Sahel of Burkina Faso through analysis of remotely-sensed and rainfall data from 1975–2011. Discussions with farmers and land management staff have helped to understand the anthropogenic efforts toward soil restoration to enable the subsistence farming agriculture. Results showed that area of barren land has been fluctuating during the study period with approximately 10-year cyclicity. Similarly, rainfall, both at national and local levels has followed the same trends. The trends of the area of barren land and rainfall variability suggest that when rainfall increases, the area of barren land decreases and barren land increases when rainfall decreases. This implies that rainfall is one of the main factors driving the change in area of barren land. In addition, humans have contributed positively and negatively to the change by restoring barren lands for agriculture using locally known techniques and by accelerating land degradation through intensive and inappropriate land use practices.
In the framework of an interference setup in which only two outcomes are possible (such as in the case of a Mach–Zehnder interferometer), we discuss in a simple and pedagogical way the difference between a standard, unitary quantum mechanical evolution and the existence of a real collapse of the wavefunction. This is a central and not-yet resolved question of quantum mechanics and indeed of quantum field theory as well. Moreover, we also present the Elitzur–Vaidman bomb, the delayed choice experiment, and the effect of decoherence. In the end, we propose two simple experiments to visualize decoherence and to test the role of an entangled particle.
The term culture of knowledge has become a commonplace today and is circulating with a confusing diversity of meanings throughout various disciplines and fields, like Cultural Studies, Science Studies, History of Science, Epistemology, Sociology and History of Knowledge. This paper investigates the origins of the term culture of knowledge and discusses its various meanings, applications, and misconceptions in Cultural Theory, History of Science, Historical Epistemology and History of Knowledge. Finally, Ludwik Fleck's theory of thought-styles is proposed as an ideal model for describing specific cultures of knowledge.
Bei herbstlichen Temperaturen machten wir uns auf ins Weitmarer Holz zur jährlichen Pilzexkursion, geleitet vom Arbeitskreis Pilzkunde Ruhr (APR). Das Gebiet gilt nicht nur als größtes zusammenhängendes Waldgebiet in Bochum, sondern lockt am frühen Sonntagmorgen offensichtlich auch sämtliche Bochumer Sportler aus den Betten, die das im weniger sportlichen Tempo voranschreitende Exkursionsgrüppchen kritisch beäugten. Neben vielen häufigen Pilzarten, die der Pilzanfänger bereits aus Exkursionen der letzten Jahre kannte und sich dankbar wieder ins Gedächtnis rief, konnte auch die eine oder andere Besonderheit wie der Bittere Schleimkopf (Cortinarius infractus) gefunden werden – ein Neufund für die Region. Die Artenliste ist auf der Homepage des Arbeitskreises Pilzkunde Ruhr (www.pilzkunde-ruhr.de) einzusehen.
"Paccan – Nuss, die mit einem Stein geknackt werden muss", so nannten die Algonkin- Indianer Nordamerikas die Nüsse der Hickory-Bäume, zu denen auch der Pekannussbaum (Carya illinoinensis, oft fälschlich Carya illinoensis geschrieben) gehört. Er ist verwandt mit der Echten Walnuss (Juglans regia). "Carya" leitet sich ab vom griechischen Wort "karyon" und bedeutet Nüsse oder Kerne. Als "Illinois nuts" brachten Pelzhändler die Nüsse an die Atlantikküste und so kamen sie zu ihrem botanischen Namen "illinoinensis", obwohl sie nicht aus Illinois stammten. Pekannüsse sind bei uns regelmäßige Bestandteile des Nusssortiments und werden besonders zur Weihnachtszeit überall angeboten. Lebende Pflanzen gibt es bei uns dagegen nur selten (z. B. in den Botanischen Gärten Bochum, Bonn und Düsseldorf).
Um auf die Problematik der Veränderung von Lebensräumen und ihre Zerstörung aufmerksam zu machen, wird jährlich von den deutschen Arbeitskreisen Heimische Orchideen (AHO) eine "Orchidee des Jahres" gewählt. Für das Jahr 2013 wurde das Purpur-Knabenkraut (Orchis purpurea) ausgewählt. Es steht insbesondere für die Gefährdung von Halbtrockenrasen.
Bei Schnee, Frost um -5 C° und eisigem Ostwind scharrte sich die für diese Verhältnisse bemerkenswert große Exkursionsgruppe um winterliche Bäume und Mauern und grub Moose aus dem Schnee. Diesmal wurde der Bereich der I-Nordstraße von IB-Gebäude bis zum Park zwischen ID und ND aufgesucht. Und der Einsatz wurde belohnt: Die Artenliste der Ruhr-Uni, die durch die Exkursionen der vergangenen Jahre bereits beachtliche Ausmaße annimmt, konnte noch um einige Arten erweitert werden.
Exkursion: Hattingen-Niederbonsfeld, geologisch-geomorphologische Exkursion im Ruhrtal am Isenberg
(2014)
Am steilen Prallhang der Ruhr zwischen Hattingen und Niederwenigern ist die vermutlich längste zusammenhängende Gesteinsfolge des Ruhrgebiets aufgeschlossen, deren südlicher Abschnitt im Rahmen der Exkursion näher betrachtet wurde. Im Mittelpunkt standen die besonders deutlich ausgeprägten Zusammenhänge zwischen der inneren geologischen Struktur des Steinkohlengebirges und dem heutigen Oberflächenrelief mit seinen markanten Bergrücken (Eggen). Die Eggen sind südlich des Ruhrtals zwischen Kettwig und Witten derart bestimmend für das Landschaftsbild, dass die entsprechenden Gebiete im Rahmen der naturräumlichen Gliederung des Ruhrgebiets durch VON KÜRTEN (1970) als Ruhr- Eggenland und Märkisches Eggenland bezeichnet werden.
Stechpalme, Efeu und Misteln gehören zu den heimischen Pflanzen, die in unseren Weihnachtsbräuchen eine wichtige Rolle spielen. Als immergrüne Arten haftet ihnen eine umfassende Symbolik an und sie beleben damit die dunkle Jahreszeit. Der Mistel kommt dabei eine besondere Bedeutung zu, die auf ihrer ungewöhnlichen Lebensweise basiert.
Eine der letzten relativ nährstoffarmen und daher artenreichen Wiesen in Bochum liegt auf dem Kalwes südlich der Fachhochschule Bochum. Sie wird allerdings zunehmend von Norden her aufgebraucht und als Bauland verwendet. Es lohnt sich daher immer wieder, diese Wiese aufzusuchen, solange sie noch existiert.
Aus dem Studentenfutter ist die leckere Cashewnuss nicht wegzudenken und manchmal findet sie sich auch auf dem Weihnachtsteller oder im Weihnachtsgebäck. Weniger bekannt sind jedoch die vielfältigen Nutzungsmöglichkeiten, die sich hinter dem exotischen Cashewbaum (auch Kaschubaum, Acajubaum oder Nierenpflanze) verbergen. Und auch eine Cashewblüte oder den sog. Cashewapfel (Kaschuapfel) bekommt man bei uns kaum einmal zu sehen, denn die Art ist hier nur in Botanischen Gärten zu finden und dort fruchtet sie nur selten.
Der Weihnachtsstern ist im mexikanischen Hochland beheimatet und wächst dort als Strauch von 4 bis 6 m Höhe. J. R. POINSETTE, seinerzeit Botschafter der USA in Mexiko, schickte 1835 Pflanzen nach Hause und begründete damit eine gärtnerische Erfolgsstory. Der Name "Poinsettia" hat sich für den Weihnachtsstern bis heute vor allem im englischen Sprachraum gehalten. Zuerst wurden die Pflanzen überwiegend als Schnittblumen kultiviert.
Der Freeden im Teutoburger Wald ist ein mit Kalk-Buchenwäldern bestandener Bergkamm. Geologisch betrachtet handelt es sich um Kalkgesteine der Oberkreide, die hier am Rand des Münsterländer Kreidebeckens aufgebogen und steil gestellt sind. Von herausragender Bedeutung ist das Naturschutzgebiet aufgrund der Vielzahl von Frühjahrsblühern.
Die Akademie der Arbeit in der Universität a.M. : ein vergessenes Stück Universitätsgeschichte
(2014)
In den Umbruchjahren der Weimarer Republik entwickelte sich in der Goethe-Universität eine Institution, die oft in Vergessenheit gerät: "Die Akademie der Arbeit in der Universität Frankfurt am Main" – so auch der offizielle Titel. Sie war und ist mehr als eine Fortbildungsstätte für Arbeitnehmer. Hier studieren jährlich 40 Arbeitnehmer, aus allen Branchen der Wirtschaft und Verwaltung ausgewählt, um sich auf verantwortliche Tätigkeiten in Unternehmen, Verbänden und öffentlichen Institutionen vorzubereiten.
Kurz nach Hitlers Machtübernahme standen auch in Frankfurt stramme Parteigänger bereit, um wichtige Posten zu übernehmen, alte Rechnungen zu begleichen und ihre jüdischen Kollegen aus den Ämtern zu drängen. Allerdings weist die Frankfurter Universität Besonderheiten auf, die ihr aus Historikerperspektive eine Ausnahmestellung sichern, denn auf ihrer Personalliste standen Namen wie von Verschuer, Mengele und Hirt. Trotz ihrer Bekanntheit ist bis heute vieles um diese Täter rätselhaft geblieben.
"Wie so oft, war es auch in Ihrem Falle leichter, Unrecht zu tun, als dieses Unrecht wieder gutzumachen." Mit dieser bitteren Bemerkung fasste im Oktober 1957 der Dekan der Wirtschafts- und Sozialwissenschaftlichen Fakultät, der Ökonom Prof. Dr. Hans Möller, in einem Entschuldigungsschreiben an Walter Braeuer ein Rehabilitierungsverfahren zusammen, das bereits mehr als zehn Jahre zuvor im Januar 1946 gestartet war.
Graben am Rand der Geschichte : Studierende des Historischen Seminars erinnern an "Verlorene Denker"
(2014)
128 Menschen – Akademiker und Intellektuelle – wurden zwischen 1933 und 1945 von der Universität Frankfurt entlassen. Das waren etwa 36 Prozent des Lehrkörpers. Als angehende Historiker in der Übung "Verlorene Denker – Die Vertreibung jüdischer Professoren an der Goethe-Universität" mit dieser Zahl konfrontiert wurden, waren sie bestürzt und verunsichert. Wie sollten sie mit den vielen Schicksalen umgehen?
Eine Liste mit den Namen von 1.794 Wissenschaftlern, die in Nazideutschland entlassen wurden, steht seit 30 Jahren im Regal des Frankfurter Neurologischen Instituts. Von dort geht die Initiative aus, ihren Urheber wiederzuentdecken: den zu Unrecht in Vergessenheit geratenen Neuropathologen Philipp Schwartz.
Die wahre Beschaffenheit der Dinge bleibt den Menschen oft verborgen. In Falle der hundert Dinge, die wir für die Jubiläumsausstellung des Universitätsarchivs Frankfurt ausgewählt und in "Hundert" für 100 Tage in der Eingangshalle des IG Farben-Hauses sichtbar gemacht haben, ist dieses Dictum Wielands wörtlich zu verstehen: Neben tausenden Blättern, zusammengeschnürt oder gereiht zwischen Aktendeckeln geschützt, um sie für mindestens 500 Jahre vor dem Verfall zu bewahren, liegen Archivboxen mit dreidimensionalen Gegenständen, die genauso einmalig sind wie jedes Stück Papier in unserem Magazin.
Als Howard Carter 1922 zum ersten Mal im Tal der Könige ins Grab von Tutenchamun blickte, sagte er: "Ich sehe wunderbare Dinge". Unbekannte Schatzkammern verbergen sich auch in den Depots, Büros, Archivräumen oder auf den Dachböden der Goethe-Universität und ihrer Kooperationspartner, wo die über 40 Sammlungen lagern. Millionen Objekte aus 4,6 Milliarden Jahren sind in über 100 Jahren Forschung und Lehre entstanden und gesammelt worden.
Der tut nix, der will nur rechnen : wie der Computer Einzug in die Geisteswissenschaften hält
(2014)
Immer mehr Texte, Töne und Bilder liegen in Bits und Bytes vor. Die Methoden der Digital Humanities werden stetig verfeinert und ermöglichen neue, bisher nicht bearbeitbare Fragestellungen. Auch in Frankfurt scheint die "empirische Wende" unaufhaltsam zu sein. Doch was hat es eigentlich mit dem neuen Forschungsgebiet auf sich, und inwiefern macht es uns schlauer oder gar klug?
Folgt der Krise des Finanzmarkts nun eine Krise der Wirtschaftswissenschaften? Die "Frankfurter Allgemeine" titelt im September auf ihrer Seite "Forschung und Lehre": "Offene Revolte in der Volkswirtschaftslehre" – damit scheint der Protest, zu dem die internationalen Studierendeninitiativen für Plurale Ökonomik im Mai aufgerufen hatten, in der Mitte der Gesellschaft angekommen zu sein.
"Ökonomische Modelle und Geschichtswissenschaften gehören zusammen", konstatiert der französische Wissenschaftler Thomas Piketty, dessen Thesen weltweit diskutiert werden, und ergänzt in einem Interview in der "Süddeutschen Zeitung" provokant: "Forscher arbeiten mit hochentwickelten Modellen und anspruchsvoller Mathematik, um Kleinigkeiten zu erklären. Manchmal zeigen diese Modelle auch gar nichts." Der Frankfurter Ökonom Bertram Schefold nimmt die Entwicklung seines Fachs – insbesondere in Frankfurt – unter die Lupe.
Die Welt des Rechts lässt sich heute nicht mehr so leicht in nationale oder internationale Sphären ordnen. Wo Lawmaker als private Akteure in einer globalisierten Ökonomie die Normen häufig nachhaltiger bestimmen als staatliches Recht, da ändern sich auch die Anforderungen an die Rechtswissenschaft.
Mit dem Namen Gerhard Quinkert verbindet man in Frankfurt vor allem die Öffnung der Chemie für die Biologie. Das war damals ein außergewöhnlicher Schritt, der dank einer gezielten Berufungspolitik realisiert wurde. Der Organische Chemiker hat das "Frankfurter Modell" Ende der 1970er Jahre entwickelt.
The ground beetle genus Cymindis is the most species rich amongst genera in the carabid subtribe Cymindidina (tribe Lebiini). Four subgenera are often recognized, i.e. Cymindis (sensu stricto) Latreille, Afrotarus Jeannel, Taridius Chaudoir and Pinacodera Schaum. Cymindis (sensu stricto) has a predominately Holarctic distribution (Hunting 2013) and includes Cymindis alutacea Wollaston, C. dohrnii Wollaston and C. anchomenoides Wollaston (the last one sometimes placed in Tarulus Bedel, either ranked as a genus or a subgenus), all three endemic to the Cape Verde Islands (Geisthardt 1988, 1996).
The abundance of humpback whales occurring around Boa Vista, Cape Verde Islands, was estimated by markrecapture modelling. Photographs of markings on tail flukes of individual whales were collected during the breeding season. Sighting histories were constructed for each individual and an abundance of 171 animals was estimated using a Jolly-Seber mark-recapture model. Correcting for known biases arising due to sex-specific behaviour and temporary emigration insofar as possible, an estimate of 260 whales was obtained. This is significantly higher than the previous estimate of 99 humpback whales from this region. Due to limited survey effort it is not known how representative the study area is of the entire Cape Verde archipelago and this estimate may be considered to be biased low and serves as a minimum estimate. The high recapture probability (0.37) coupled with the low abundance is consistent with a small local population. The low survival rate (0.86) suggests possible emigration and further studies are needed to assess connectivity between humpback whales breeding in Cape Verde and other breeding locations. The amount of exchange between groups of whales breeding in Cape Verde and adjacent areas remains unknown. It is unclear whether the abundance estimate herein applies to part of an isolated population or part of a larger and continuous one.
Black-winged stilt Himantopus himantopus (Linnaeus, 1758) has a wide geographical distribution, including France and southern Iberia to sub-Saharan Africa and Madagascar, and east to central Asia and northern central China, India, Sri Lanka, Indochina and Taiwan (Pierce 1996). On the African mainland, breeding sites nearest to the Cape Verde Islands are in Mauritania and Senegal (Isenmann et al. 2010, Borrow & Demey 2014).
Recent data on status and distribution of resident and migrant birds in the Cape Verde Islands are presented, including records of nine taxa new to the archipelago, viz. Ciconia nigra, Ciconia ciconia, Circus macrourus, Falco naumanni, Chlidonias hybrida, Chlidonias leucopterus, Apus affinis, Ptyonoprogne fuligula and Phylloscopus inornatus. Also presented are data on a number of breeding taxa, including the first record of the endemic Cape Verde purple heron Ardea bournei outside Santiago island. The alarming situation of the magnificent frigatebird Fregata magnificens, of which only three individuals remain in Cape Verde, constituting the entire population in the East Atlantic, remains of great concern. Several species of birds of prey are also highly threatened and have already become extinct in some islands. Following its expansion through Northwest Africa and the Canary Islands, Eurasian collared dove Streptopelia decaocto has now also become established in at least three of the Cape Verde Islands.
The zoogeographic composition of the coastal ichthyofauna of the Cape Verde archipelago shows a predominance of Guinean species, followed by tropical-subtropical (amphi-Atlantic) fishes and several endemic species. Recent taxonomic revisions, new species descriptions, new fish records in the area and recent ecological surveys of intra-specific fish interaction as well as emergent research on seamounts in national waters warrant an up-to-date review of research on the ichthyofauna of Cape Verde. An updated percentage of endemic coastal reef fish of 10.2% attest significant speciation in Cape Verde waters. Almost half of the total cryptobenthic fish species richness in Cape Verde comprises endemic species, some of them newly discovered. Examples of endemism are discussed, notably white seabream Diplodus sargus lineatus, bulldog dentex Dentex (Virididentex) acromegalus, blackfish drummer Girella stuebeli, Lubbock's chromis Chromis lubbocki, Cape Verde damselfish Similiparma hermani and Guinean parrotfish Scarus hoefleri. Cape Verde diverges considerably from the other Macaronesian island groups in terms of its ichthyofauna and its uniqueness warrants special attention by governmental agencies and conservation organizations.
During an entomological survey in Santiago Island, Cape Verde Islands, in November-December 2011 in order to study the bio-ecology and susceptibility to insecticides of Anopheles arabiensis Patton, 1905, Culex tritaeniorhynchus Giles, 1901 was found to be present in the Santa Cruz District. Both adult and immature specimens were collected and a description of both is given. Further confirmation of the taxonomic identity of the specimens was obtained from studying the male genitalia. This is the first known occurrence of Culex tritaeniorhynchus (a primary vector of Japanese encephalitis in eastern and southern Asia and a potential vector of West Nile Virus, Sindbis and Rift Valley Fever Virus) in the Cape Verde Islands.
Fernerkundung und GPS, Massenspektrometrie und Röntgenfluoreszenzanalyse: In der Archäologie gehören diese naturwissenschaftlichen Methoden inzwischen zum Standard-Repertoire. Was macht dies mit einem Fach, das sich selbst als eine der wichtigsten Kulturwissenschaften sieht? Lassen sich Fragen zum Leben unserer Vorfahren heute aus anderen Blickwinkeln beantworten?
"Ach!" würde Goethe vermutlich ausrufen, sähe er die Kleinteiligkeit der heutigen Forschung – und auch sein Faust verzweifelt am gestaltlosen "Wissensqualm". Goethe wehrt sich vehement gegen eine Zersplitterung der Wissenschaft in unzählige Einzelphänomene. Er schätzt die Universalisten, "die das Allgemeine im Auge haben und gern das Besondere an- und einfügen möchten".
Ohne Drittmittel für seine Forschung kommt kaum noch ein Wissenschaftler aus. Immer mehr kostbarer Zeit verbringen Forscher damit, endlose Anträge auszufüllen. Antragsprosa ist längst eine Wissenschaft für sich. Der Jurist Rainer Maria Kiesow hat seine Form des "exzellenten Anschreibens" gefunden – eine Glosse mit spitzer Feder geschrieben.
Die Erfolgsquote von rund 10 Prozent ist gering, der Arbeitseinsatz hoch. Doch weil die Europäische Union Fördersummen in Millionenhöhe ausschüttet, ermutigt die Universität ihre Wissenschaftler, Anträge zu stellen und unterstützt sie dabei. Der Wirtschaftsjournalist Dr. Michael Braun hat die Beteiligten nach den Schlüsseln zum Erfolg gefragt.
Die Nationalsozialisten zerstörten seine Kindheit, raubten ihm die Jugend: Josef Buchmann überlebte die Konzentrationslager. Er gab nie auf, wurde ein erfolgreicher Unternehmer. Nachwuchsforscher und die Wissenschaft zu unterstützen, das sieht er – der selbst nicht studieren konnte – als "sein Lebenswerk" an.
Von den hart umkämpften Anfängen des Frauenstudiums bis heute hat sich viel verändert. Doch Familienplanung und Mobilität sind weiterhin kritische Punkte für weibliche Karrieren in der Forschung. Deswegen sind Wissenschaftlerinnen auch heute noch häufiger kinderlos als ihre männlichen Kollegen. Erst allmählich schärfen Genderprogramme das Bewusstsein für die nicht fachlichen Aspekte der Nachwuchsförderung beider Geschlechter. Und Mentoringprogramme helfen Frauen bei den letzten Schritten zur Professur wie Networking, Auftreten, Bewerben und Verhandeln.
Jetzt, nach Beendigung vieler Jahre der Lehre und Forschung an der Goethe-Universität, kann ich diese Zeit mit einem Abstand überdenken. Der Freiraum für solch nicht zweckgerichtetes Verhalten ist während der praktischen Tätigkeit an der Universität äußerst gering und muss hart erkämpft werden, wie jedes Stück Freiheit. Rückblickend sehe ich, dass der Wunsch, über das Detailwissen hinaus ganzheitliche Zusammenhänge zu betrachten und über die eigene Fachgrenze hinauszugehen, meinen Weg geprägt hat.
Seit 50 Jahren ist Eckhard Henscheid schon Mitglied der "Neuen Frankfurter Schule" – Deutschlands "erfolgreichster Boygroup" (Oliver Maria Schmitt). Doch in welchem Verhältnis steht die "Neue" eigentlich zur "Alten" Frankfurter Schule von Horkheimer, Adorno & Co? Impliziert die Namensgebung (heimlichen) Respekt oder (ironische) Distanz? Hat die "Spaßgesellschaft" der Kritischen Theorie endgültig den Garaus gemacht?
Seit 2010 wetteifern Naturwissenschaftler bei den Science Slams des Physikalischen Vereins darum, wer seine Forschung am unterhaltsamsten erklären kann.
Im Jubiläumsjahr beteiligten sich erstmals auch die Geisteswissenschaftler an dem Format. Jeder Referent hat höchstens zehn Minuten für zündende Ideen, witzige Einlagen und überraschende Pointen. Zum Schluss entscheidet das Publikum, wer Slam-Champion ist.
Im November traten die drei besten Slammer der beiden Vorrunden vom Juli zum großen Finale gegeneinander an. 1.200 Besucher im Audimax des Campus Westend wählten den Informatiker Johannes Schildgen in einem knappen Kopf-an-Kopf-Rennen mit Kai Jäger zum Sieger.
Background: In primary care, patients with multiple chronic conditions are the rule rather than the exception. The Chronic Care Model (CCM) is an evidence-based framework for improving chronic illness care, but little is known about the extent to which it has been implemented in routine primary care. The aim of this study was to describe how multimorbid older patients assess the routine chronic care they receive in primary care practices in Germany, and to explore the extent to which factors at both the practice and patient level determine their views.
Methods: This cross-sectional study used baseline data from an observational cohort study involving 158 general practitioners (GP) and 3189 multimorbid patients. Standardized questionnaires were employed to collect data, and the Patient Assessment of Chronic Illness Care (PACIC) questionnaire used to assess the quality of care received. Multilevel hierarchical modeling was used to identify any existing association between the dependent variable, PACIC, and independent variables at the patient level (socio-economic factors, weighted count of chronic conditions, instrumental activities of daily living, health-related quality of life, graded chronic pain, no. of contacts with GP, existence of a disease management program (DMP) disease, self-efficacy, and social support) and the practice level (age and sex of GP, years in current practice, size and type of practice).
Results: The overall mean PACIC score was 2.4 (SD 0.8), with the mean subscale scores ranging from 2.0 (SD 1.0, subscale goal setting/tailoring) to 3.5 (SD 0.7, delivery system design). At the patient level, higher PACIC scores were associated with a DMP disease, more frequent GP contacts, higher social support, and higher autonomy of past occupation. At the practice level, solo practices were associated with higher PACIC values than other types of practice.
Conclusions: This study shows that from the perspective of multimorbid patients receiving care in German primary care practices, the implementation of structured care and counseling could be improved, particularly by helping patients set specific goals, coordinating care, and arranging follow-up contacts. Studies evaluating chronic care should take into consideration that a patient’s assessment is associated not only with practice-level factors, but also with individual, patient-level factors.
The exact pathophysiology of contrast-induced nephropathy (CIN) is not fully clarified, yet the osmotic characteristics of contrast media (CM) have been a significant focus in many investigations of CIN. Osmotic effects of CM specific to the kidney include transient decreases in blood flow, filtration fraction, and glomerular filtration rate. Potentially significant secondary effects include an osmotically induced diuresis with a concomitant dehydrating effect. Clinical experiences that have compared the occurrence of CIN between the various classes of CM based on osmolality have suggested a much less than anticipated advantage, if any, with a lower osmolality. Recent animal experiments actually suggest that induction of a mild osmotic diuresis in association with iso-osmolar agents tends to offset potentially deleterious renal effects of high viscosity-mediated intratubular CM stagnation.
Carinostoma elegans new to the Slovakian harvestmen fauna (Opiliones, Dyspnoi, Nemastomatidae)
(2014)
A new genus and species of small harvestman was found for the first time in Slovakia – Carinostoma elegans (Sorensen, 1894). One male and two females were collected in the Mlyňany arboretum of the Slovak Academy of Science (western Slovakia). Descriptions and photographs of both sexes of C. elegans are provided. Additional comments, and a map of distribution of all species of this genus, are provided.
Sauron rayi (Simon, 1881) is recorded in Austria for the first time. Male and female specimens of this rare European spider were found in two “Austrian pine forests” in Lower Austria. Data on distribution, habitat, phenology and Red List status from the Austrian localities and from published records in other countries are presented.
Jörg Wunderlich wurde am 19. Dezember 1939 in Berlin geboren. Nach dem zweiten Weltkrieg befand sich seine Familie im Osten des Landes, es gelang ihr aber 1951 nach West-Berlin zu ziehen. Aufgrund der mangelnden schulischen Ausbildung in der Nachkriegszeit und der unterschiedlichen Schulprogramme im Osten (Russisch) und Westen (Latein und Englisch) schloss Jörg die Schule im Alter von 20 Jahren ab.
Danach begann er an der Freien Universität Berlin zunächst Mathematik zu studieren, wechselte aber bald zu Biologie, Geographie, Politikwissenschaften und Philosophie. Insgesamt verbrachte er acht Jahre an der Universität. Währenddessen übernahm er Jobs um sich seinen Lebensunterhalt zu finanzieren. Seine Staatsexamensarbeit an der Freien Universität war eine ökologische Studie über die Zwergspinnenfauna der Pfaueninsel in Berlin, einem Naturschutzgebiet, in dem er über 300 Webspinnenarten in verschiedenen Habitaten nachwies, zwei davon neu für die Wissenschaft (Glyphesis taoplesius, Moebelia berolinensis).
Die Springspinne Evarcha michailovi Logunov, 1992 wird erstmalig für Deutschland von einem ehemaligen Truppenübungsplatz im Süden Mecklenburg-Vorpommerns gemeldet. Gleichzeitig werden Erstnachweise der Springspinnen Evarcha laetabunda (C. L. Koch, 1846), Philaeus chrysops (Poda, 1761) und Sitticus inexpectus Logunov & Kronestedt, 1997, der Haubennetzspinne Crustulina sticta (O. P.-Cambridge, 1861) sowie der Krabbenspinne Heriaeus graminicola (Doleschall, 1852) erbracht.