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We report measurements of Xi and Xi-bar hyperon absolute yields as a function of rapidity in 158 GeV/c Pb+Pb collisions. At midrapidity, dN/dy = 2.29 +/- 0.12 for Xi, and 0.52 +/- 0.05 for Xi-bar, leading to the ratio of Xi-bar/Xi = 0.23 +/- 0.03. Inverse slope parameters fitted to the measured transverse mass spectra are of the order of 300 MeV near mid-rapidity. The estimated total yield of Xi particles in Pb+Pb central interactions amounts to 7.4 +/- 1.0 per collision. Comparison to Xi production in properly scaled p+p reactions at the same energy reveals a dramatic enhancement (about one order of magnitude) of Xi production in Pb+Pb central collisions over elementary hadron interactions.
The directed and elliptic flow of protons and charged pions has been observed from the semi-central collisions of a 158 GeV/nucleon Pb beam with a Pb target. The rapidity and transverse momentum dependence of the flow has been measured. The directed flow of the pions is opposite to that of the protons but both exhibit negative flow at low pt. The elliptic flow of both is fairly independent of rapidity but rises with pt. PACS numbers: 25.75.-q, 25.75.Ld
Using the NA49 main TPC, the central production of hyperons has been measured in CERN SPS Pb - Pb collisions at 158 GeV c-1. The preliminary ratio, studied at 2.0 < y < 2.6 and 1 < pT < 3 GeV c-1, equals ~ (13 ± 4)% (systematic error only). It is compatible, within errors, with the previously obtained ratios for central S + S [1], S + W [2], and S + Au [3] collisions. The fit to the transverse momentum distribution resulted in an inverse slope parameter T of 297 MeV. At this level of statistics we do not see any noticeable enhancement of hyperon production with the increased volume (and, possibly, degree of equilibration) of the system from S + S to Pb + Pb. This result is unexpected and counterintuitive, and should be further investigated. If confirmed, it will have a significant impact on our understanding of mechanisms leading to the enhanced strangeness production in heavy-ion collisions.
Preliminary data on phi production in central Pb + Pb collisions at 158 GeV per nucleon are presented, measured by the NA49 experiment in the hadronic decay channel phi - K+K-. At mid-rapidity, the kaons were separated from pions and protons by combining dE/dx and time-of-flight information; in the forward rapidity range only dE/dx identification was used to obtain the rapidity distribution and a rapidity-integrated mt-spectrum. The mid-rapidity yield obtained was dN/dy = 1.85 ± 0.3 per event; the total phi multiplicity was estimated to be 5.0 ± 0.7 per event. Comparison with published pp data shows a slight, but not very significant strangeness enhancement.
The large acceptance TPCs of the NA49 spectrometer allow for a systematic multidimensional study of two-particle correlations in different part of phase space. Results from Bertsch-Pratt and Yano-Koonin-Podgoretskii parametrizations are presented differentially in transverse pair momentum and pair rapidity. These studies give an insight into the dynamical space-time evolution of relativistic Pb+Pb collisions, which is dominated by longitudinal expansion.
Lambda and Antilambda reconstruction in central Pb+Pb collisions using a time projection chamber
(1997)
The large acceptance time projection chambers of the NA49 experiment are used to record the trajectory of charged particles from Pb + Pb collisions at 158 GeV per nucleon. Neutral strange hadrons have been reconstructed from their charged decay products. To obtain distributions of Λ, and Ks0 in discrete bins of rapidity, y, and transverse momentum, pT, calculations have been performed to determine the acceptance of the detector and the efficiency of the reconstruction software as a function of both variables. The lifetime distributions obtained give values of cτ = 7.8 ± 0.6 cm for Λ and cτ = 2.5 ± 0.3 cm for Ks0, consistent with data book values.
The bile acid activated transcription factor farnesoid X receptor (FXR) regulates numerous metabolic processes and is a rising target for the treatment of hepatic and metabolic disorders. FXR agonists have revealed efficacy in treating non-alcoholic steatohepatitis (NASH), diabetes and dyslipidemia. Here we characterize imatinib as first-in-class allosteric FXR modulator and report the development of an optimized descendant that markedly promotes agonist induced FXR activation in a reporter gene assay and FXR target gene expression in HepG2 cells. Differential effects of imatinib on agonist-induced bile salt export protein and small heterodimer partner expression suggest that allosteric FXR modulation could open a new avenue to gene-selective FXR modulators.
Der Ursprung der Masse bekannter Teilchen und der Einschlu der Quarks in Hadronen ist einer der grundlegendsten Fragestellungen der modernen Physik. Die Kenntnis des Verhaltens von Kernmaterie unter extremen Bedingungen ist unabdingbar zum Verstandnis der Evolution des Universums und zur Theoriebildung von stellaren Objekten wie Neutronensternen und schwarzen Löchern. Einen experimentellen Zugang zur Untersuchung dieser Problematik stellt die Erzeugung heier und dichter Kernmaterie in ultrarelativistischen Schwerionenkollisionen dar. Hierzu untersucht das NA49 Experiment seit Herbst 1994 am 208-Pb-Strahl des CERN-SPS Pb+Pb Kollisionen bei 158 GeV pro Nukleon. Ein Schwerpunkt des Forschungsprogrammes liegt in der Untersuchung des Zustandes der Materie in der frühen Phase der Reaktion. Nach gegenwartem Stand der Theorie wird bei genugent hoher Energiedichte der Einschlu der Quarks in Hadronen aufgebrochen und ein Zustand der Materie erzeugt, in welchen die eektiven Freiheitsgrade von Hadronen und Hadronen-Resonanzen in die von Quarks und Gluonen übergehen - das sogenannte Quark-Gluon-Plasma (QGP). Die Honung ist nun, da sich die Formation eines solchen QGP im hadronischen Endzustand wiederspiegelt. Es wird erwartet, da die Seltsamkeitsproduktion in einem QGP sich in ihrer Rate und ihren Gleichgewichtswerten von der in einem hadronischen Feuerball-Szenario unterscheidet und sich somit als Signatur fur die Erzeugung eines GQP eignet. Von besonderen Interesse ist hier die Produktion von Hyperonen. Schwerpunkt dieser Arbeit ist die Untersuchung der Produktion von doppelt seltsamen geladenen -Hyperonen in zentralen Pb+Pb Kollisionen. Zu diesem Zweck wurden 58000 zentrale Pb+Pb Ereignisse der im Herbst 1995 aufgezeichneten Reaktionen untersucht. Die Analyse der Daten wurde auschlielich mit der zweiten Spurendriftkammer (VTPC2) durchgeführt. Zur Rekonstruktion der -Hyperonen muten Verfahren entwickelt werden, um die typischen Zerfalls-Topologien der doppelt seltsamen Hyperonen aus der Vielzahl von ca. 700 in der Vertex-TPC gemessenen geladenen Teilchenspuren herauszulösen. Aus den in der kombinatorischen Analyse rekonstruierten 720 und 138 + - Hyperonen konnten Spektren des Transversalimpulses und Rapiditatsverteilungen ermittelt werden. Die gewonnene Phasenraum-Akzeptanz fur die in der VTPC2 gemessenen und + - Hyperonen beträgt ....