Refine
Year of publication
Language
- English (512)
Has Fulltext
- yes (512)
Is part of the Bibliography
- no (512)
Keywords
- BESIII (19)
- e +-e − Experiments (16)
- Branching fraction (12)
- Particle and Resonance Production (8)
- Quarkonium (7)
- Charm Physics (6)
- Spectroscopy (6)
- Hadronic decays (5)
- Branching fractions (4)
- Charmonium (4)
- Exotics (4)
- Heavy-ion collisions (4)
- Lepton colliders (4)
- Charmed mesons (3)
- Diffraction (3)
- Electroweak interaction (3)
- Initial state radiation (3)
- QCD (3)
- e+-e− Experiments (3)
- Absolute branching fraction (2)
- Beam Energy Scan (2)
- Bhabha (2)
- Charm physics (2)
- Chiral Magnetic Effect (2)
- Collectivity (2)
- Correlation (2)
- Cross section (2)
- Elastic scattering (2)
- Electroweak Interaction (2)
- Flavour Physics (2)
- Hadronic cross section (2)
- Leptonic, semileptonic & radiative decays (2)
- Muon anomaly (2)
- Particle decays (2)
- Pion form factor (2)
- Radiative decay (2)
- Shear viscosity (2)
- decays (2)
- Angular distribution (1)
- Annihilation (1)
- Atherosclerosis (1)
- Autophagic cell death (1)
- B-slope (1)
- BESIII detector (1)
- Beam energy scan (1)
- Biochemical simulations (1)
- Bipolar disorder (1)
- Born cross section (1)
- Born cross section measurement (1)
- Branching fraction measurement (1)
- Bromodomänen (1)
- CP violation (1)
- Canonical suppression (1)
- Cardiovascular diseases (1)
- Charged-particle multiplicity (1)
- Charm quark spatial diffusion coefficient (1)
- Charm vector (1)
- Charmed baryon (1)
- Charmonium (-like) (1)
- Chemische Sonden (1)
- Chiral magnetic effect (1)
- Circadian (1)
- Coalescence (1)
- Cold nuclear matter effects (1)
- Covariance matrix (1)
- Critical point (1)
- Cross section measurements (1)
- D meson (1)
- D0 and D+ mesons (1)
- Dalitz decay (1)
- Dark photon (1)
- Dark sector (1)
- Denosumab (1)
- Deuteron production (1)
- Di-hadron correlations (1)
- D⁰ meson (1)
- Effective form factor (1)
- Electromagnetic amplitude (1)
- Electromagnetic form factor (1)
- Electromagnetic form factors (1)
- Elliptic flow (1)
- Epigenetik (1)
- Experimental nuclear physics (1)
- Experimental particle physics (1)
- Extension study (1)
- FOS: Physical sciences (1)
- FREEDOM (1)
- Flavor changing neutral currents (1)
- Flavor symmetries (1)
- Form factors (1)
- Forward physics (1)
- Free energy (1)
- Germany (1)
- Groomed jet radius (1)
- Hadron-Hadron scattering (experiments) (1)
- Hadronization (1)
- Hadrons (1)
- Health risk analysis (1)
- Heavy Ion Experiments (1)
- Heavy Quark Production (1)
- Heavy ion collisions (1)
- Heavy-Ion Collision (1)
- Heavy-flavor decay electron (1)
- Helicity amplitude analysis (1)
- High Energy Physics - Experiment (hep-ex) (1)
- Higher moments (1)
- Hyperons (1)
- Inclusive branching fraction (1)
- Interference fragmentation function (1)
- Invisible decays (1)
- Italy (1)
- J/ψ suppression (1)
- Jet substructure (1)
- K0S (1)
- Medizinische Chemie (1)
- Membrane fusion (1)
- Membrane structures (1)
- Molecular dynamics (1)
- Multiple parton interactions (1)
- Myocardial infarction (1)
- Neolithic (1)
- Net-charge correlations (1)
- Net-charge fluctuations (1)
- Neutrinos (1)
- Osteoporosis (1)
- Particle and resonance production (1)
- Particle phenomena (1)
- Particle production (1)
- Phase (1)
- Polarization (1)
- Proton (1)
- Proton-proton collisions (1)
- Proton–proton collisions (1)
- Psychiatry (1)
- Quantum chromodynamics (1)
- Quark–gluon plasma (1)
- R value (1)
- RHIC (1)
- Rare decays (1)
- Resonances (1)
- STAR (1)
- Seasonal variation (1)
- Selection bias (1)
- Semi-leptonic decays (1)
- SoftDrop (1)
- Solar insolation (1)
- Splitting function (1)
- Strangeness enhancement (1)
- Stroke (1)
- Strong amplitude (1)
- Strukturbasiertes Design (1)
- Suicide (1)
- Sunlight (1)
- Sweden (1)
- Techniques Electromagnetic calorimeters (1)
- Thermal model (1)
- Threshold effect (1)
- Transversity (1)
- Triple quarkonia (1)
- Vesicle fusion (1)
- Vesicles (1)
- W-exchange (1)
- Y (4260) (1)
- Y states (1)
- branching fractions (1)
- bromodomains (1)
- center-of-mass energy (1)
- charmed baryon (1)
- charmonium-like states (1)
- chemical probes (1)
- decay (1)
- dimuon (1)
- diphoton (1)
- domestication (1)
- e+e − annihilation (1)
- e+e⁻ − Experiments (1)
- e+e− Experiments (1)
- e+e− annihilation (1)
- electron-positron collision (1)
- epigenetics (1)
- evolution (1)
- gene flow (1)
- hadron spectroscopy (1)
- hadronic events (1)
- heavy-ion collisions (1)
- helicity amplitude analysis (1)
- inclusive J/ψ decays (1)
- luminosity (1)
- medicinal chemistry (1)
- number of J/ψ events (1)
- p+p collisions (1)
- structure-based design (1)
- tetraquark (1)
- trigger efficiency (1)
- Λ+c baryon (1)
- Λc⁺ (1)
- Σ hyperon (1)
- Υ suppression (1)
- ψ(3686) (1)
Institute
- Physik (399)
- Frankfurt Institute for Advanced Studies (FIAS) (101)
- Medizin (6)
- Institut für Ökologie, Evolution und Diversität (1)
- Kulturwissenschaften (1)
- Pharmazie (1)
- Psychologie (1)
Background: Pythium ultimum (P. ultimum) is a ubiquitous oomycete plant pathogen responsible for a variety of diseases on a broad range of crop and ornamental species. Results: The P. ultimum genome (42.8 Mb) encodes 15,290 genes and has extensive sequence similarity and synteny with related Phytophthora species, including the potato blight pathogen Phytophthora infestans. Whole transcriptome sequencing revealed expression of 86% of genes, with detectable differential expression of suites of genes under abiotic stress and in the presence of a host. The predicted proteome includes a large repertoire of proteins involved in plant pathogen interactions although surprisingly, the P. ultimum genome does not encode any classical RXLR effectors and relatively few Crinkler genes in comparison to related phytopathogenic oomycetes. A lower number of enzymes involved in carbohydrate metabolism were present compared to Phytophthora species, with the notable absence of cutinases, suggesting a significant difference in virulence mechanisms between P. ultimum and more host specific oomycete species. Although we observed a high degree of orthology with Phytophthora genomes, there were novel features of the P. ultimum proteome including an expansion of genes involved in proteolysis and genes unique to Pythium. We identified a small gene family of cadherins, proteins involved in cell adhesion, the first report in a genome outside the metazoans. Conclusions: Access to the P. ultimum genome has revealed not only core pathogenic mechanisms within the oomycetes but also lineage specific genes associated with the alternative virulence and lifestyles found within the pythiaceous lineages compared to the Peronosporaceae.
Aims: Carotid intima media thickness (CIMT) predicts cardiovascular (CVD) events, but the predictive value of CIMT change is debated. We assessed the relation between CIMT change and events in individuals at high cardiovascular risk.
Methods and results: From 31 cohorts with two CIMT scans (total n = 89070) on average 3.6 years apart and clinical follow-up, subcohorts were drawn: (A) individuals with at least 3 cardiovascular risk factors without previous CVD events, (B) individuals with carotid plaques without previous CVD events, and (C) individuals with previous CVD events. Cox regression models were fit to estimate the hazard ratio (HR) of the combined endpoint (myocardial infarction, stroke or vascular death) per standard deviation (SD) of CIMT change, adjusted for CVD risk factors. These HRs were pooled across studies.
In groups A, B and C we observed 3483, 2845 and 1165 endpoint events, respectively. Average common CIMT was 0.79mm (SD 0.16mm), and annual common CIMT change was 0.01mm (SD 0.07mm), both in group A. The pooled HR per SD of annual common CIMT change (0.02 to 0.43mm) was 0.99 (95% confidence interval: 0.95–1.02) in group A, 0.98 (0.93–1.04) in group B, and 0.95 (0.89–1.04) in group C. The HR per SD of common CIMT (average of the first and the second CIMT scan, 0.09 to 0.75mm) was 1.15 (1.07–1.23) in group A, 1.13 (1.05–1.22) in group B, and 1.12 (1.05–1.20) in group C.
Conclusions: We confirm that common CIMT is associated with future CVD events in individuals at high risk. CIMT change does not relate to future event risk in high-risk individuals.