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Annihilation dynamics plays a fundamental role in the baryon−antibaryon interaction (B−B¯¯¯¯) at low-energy and its strength and range are crucial in the assessment of possible baryon bound states. Experimental data on annihilation cross sections are available for the p−p¯¯¯ system but not in the low relative momentum region. Data regarding the BB¯¯¯¯ interaction with strange degrees of freedom are extremely scarce or absent, hence the modeling of the annihilation contributions is mainly based on nucleon−antinucleon (N−N¯¯¯¯) results, when available. In this letter we present a measurement of the p−p¯¯¯, p−Λ¯¯¯¯⊕p¯¯¯−Λ and Λ−Λ¯¯¯¯ interaction using correlation functions in the relative momentum space in high-multiplicity triggered pp collisions at s√=13 TeV recorded by ALICE at the LHC. In the p−p¯¯¯ system the couplings to the mesonic channels in different partial waves are extracted by adopting a coupled-channel approach with recent χEFT potentials. The inclusion of these inelastic channels provides good agreement with the data, showing a significant presence of the annihilation term down to zero momentum. Predictions obtained using the Lednický−Lyuboshits formula and scattering parameters obtained from heavy-ion collisions, hence mainly sensitive to elastic processes, are compared with the experimental p−Λ¯¯¯¯⊕p¯¯¯−Λ and Λ−Λ¯¯¯¯ correlations. The model describes the Λ−Λ¯¯¯¯ data and underestimates the p−Λ¯¯¯¯⊕p¯¯¯−Λ data in the region of momenta below 200 MeV/c. The observed deviation indicates a different contribution of annihilation channels to the two systems containing strange hadrons.
Background: To compare severe infectious complication rates after transrectal prostate biopsies between cephalosporins and fluoroquinolones for antibiotic monoprophylaxis.
Material and Methods: In the multi-institutional cohort, between November 2014 and July 2020 patients received either cefotaxime (single dose intravenously), cefpodoxime (multiple doses orally) or fluoroquinolones (multiple-doses orally or single dose intravenously) for transrectal prostate biopsy prophylaxis. Data were prospectively acquired and retrospectively analyzed. Severe infectious complications were evaluated within 30 days after biopsy. Logistic regression models predicted biopsy-related infectious complications according to antibiotic prophylaxis, application type and patient- and procedure-related risk factors.
Results: Of 793 patients, 132 (16.6%) received a single dose of intravenous cefotaxime and were compared to 119 (15%) who received multiple doses of oral cefpodoxime and 542 (68.3%) who received fluoroquinolones as monoprophylaxis. The overall incidence of severe infectious complications was 1.0% (n=8). No significant differences were observed between the three compared groups (0.8% vs. 0.8% vs. 1.1%, p=0.9). The overall rate of urosepsis was 0.3% and did not significantly differ between the three compared groups as well.
Conclusion: Monoprophylaxis with third generation cephalosporins was efficient in preventing severe infectious complications after prostate biopsy. Single intravenous dose of cefotaxime and multiday regimen of oral cefpodoxime showed a low incidence of infectious complications <1%. No differences were observed in comparison to fluoroquinolones.